Business growth over the past 26 years has

allowed over 1,300 PSL installations worldwide.

1989 PSL founded in Liverpool, UK

1991 PSL achieved extreme containment

1992PSL project leaders (acting on behalf of UNICEF) developed a solution to eliminate goitre in children in Bangladesh.

1999 Duke of Westminster Award & Queen’s Award for Export Achievement

2001 HRH Prince Andrew visited PSL UK

2004 PSL Filter Dryer redesigned to achieve 2.5ppm reflux cleaning

2009 PSL pioneering CakeStand Tray Dryer design launched

2010 Launch of the Glass Filter Dryer (GFD®)

2013 Pioneering MicroSphere RefinerTM design launched

2013 Best Pharma Technology Provider @ Asia Manufacturing Awards

2014 New addition to GFD range with Stainless Steel Vessel

2014 Best Pharma Technology Provider @ Asia Manufacturing Awards

2014 Best Manufacturing Business @ E3 Business Awards

2015 Best International Business @ NW Entrepreneur Awards

2015 Liverpool Lord Mayor visited PSL UK

2015 Nominated for Exported by Britain by constituency’s MP

2015 Winner of the ACHEMA Innovation Award, Mechanical Processes

2016 Export Champion from the UK Trade & Investment

Worldwide

PSL continues to increase its number of global offices, agents and distributors to aid the smooth distribution

of its equipment to any part of the world.

Supporting global pharmaceutical, biopharmaceutical, chemical and laboratory

industries since 1989.

See PSL’s Customers Testimonials: http://www.powdersystems.com/testimonials.html

Full Scale Ergonomic Mock-upDetailed 3D Modeling …Up to Complete Installation

PSL’s Approach: ‘Solution Efficiency’

PSL takes client’s vision and translates it into their project, providing complete solution efficiency.

From lab and R&D to production and complex full process systems.

• Agitated Nutsche Filter Dryers

• Nano-Containment Isolators

Products

• Vacuum Tray Dryers

• Microsphere Formulation

Quality Insurance

PSL operates to the highest level of Good Manufacturing Practice (cGMP) and complies with

global regulatory bodies:

ISO 9001:2008 | cGMP | GAMP | CE | ATEX | ASME| PED | UL

Full Process Solutions1) Raw Materials

(Dispensing/Sampling/Charging)

2) Reaction/

Fermentation

3) Filtration/

Drying4) Conditioning

5) Formulation

Dispensing and Sampling

Nano-Containment

PSL’s isolators are designed for Laboratories, Clinical Trials

and Production facilities.

• Accommodate all sizes of pharmaceutical

containers

• Achieve high containment levels

• Versatile Solutions

• Powder handling through split valves,

airlocks, rapid transfer ports (RTPs) and

bag out ports

• Completely integrated design: including

hoists, weigh systems, transfer devices,

CIP and safety

Containment

Charging

• FIBC reactor direct charging

• Compact small-scale charging isolator

• Slurry vessel charging

• Reactor charging with pressure rated plug

Filter Dryers

PSL’s filter dryers are designed for washing and isolating solids with or without integrated

containment systems.

Laboratory (GFD®) Kilo Laboratory Pilot Plant Commercial Production

0.002m2 to 0.05m2 0.03m2 to 0.125m2 0.3m2 to 0.6m2 1m2 to 4m2

• Highly efficient drying including direct underplate heating

with no air gap between the base and filtration media

• Minimum gap design

• Reflux cleaning at 2.5ppm to none detectable

• Special agitator design

• Minimum solvent volumes beneath mesh

• Pioneers of direct heal recovery system

Filter Dryers

Laboratory Glass Filter Dryers

is a miniature version of a PSL production filter dryer for easy lab-scale filtration and drying.

0.002m2 0.01m2 0.05m2

Laboratory Glass Filter Dryers

Lab scale filtration and drying with the same reliability and

benefits as full size PSL filter dryer products:

• Batch homogeneity

• Improved yield

• Reduced product exposure

• Minimum process disruption

• Easy cleaning

• Process visibility

• Removable filter basket

Lab scale filtration and drying with metallic vessel for higher pressure requirement and

direct scale up.

Laboratory Filter Dryers

Pilot Plant Simple Filter Dryer

• Heated jacket for drying

• Different filtration media

• Vessel discharge hatch

• Nitrogen purged GloveBag with airlock

• Contained sampling

Kilo Laboratory Filter Dryers

• Contained discharge, heel removal and sampling

• Available as mobile solution

• Contained discharge

• Fully scalable solution

• Maximum product yield

0.05m² - 0.125m²

Small Scale Production Filter Dryers

0.3m² to 0.6m²

Large Scale Production Filter Dryers

• High containment heel and product recovery system available

1m² to 5m²

Laboratory (GFD® FilterBox) Kilo Laboratory FilterBox Pilot Plant FilterBox

0.002m2 & 0.01m2 0.05m2 0.125m2 to 0.4m2

High Containment Filter Dryers

Contained filtration and drying through a fully integrated lab to production filter dryer inside a

high containment glove box.

Tray Dryer

Tray Dryers

PSL tray dryers can operate in

down flow booths, clean rooms or

in conjunction with PSL

containment isolators.

• Uniform direct tray heating

• Total ease of cleaning

• Enhanced ergonomics

MicroSphere Refiner

PSL developed the unique Refiner technology for microsphere formulation from small scale

processes up to production.

Microsphere Scalping & Refiner Range

R&D Scale Production Scale

0.002m2 to 0.01m2 0.03m² & 0.05m² 0.125m2 to 0.3m2 Filtration Area

10 to 100 grams 100g to 4.5Kgs > 4.5Kgs Quantity

Non – Sterile Sterile & Non-Sterile Sterile Sterility

R&D and Small Scale Microsphere Refiners

0.03m² and 0.05m²

CIP and SIP capabilities

Tiltable discharge

Large Scale Microsphere Refiner

0.125m² and 0.3m²

• Gas lift-off mechanical seals

• Unique off-loading designs

• CIP and SIP capabilities

Containment

Offloading

PSL’s FlowBox is a single drum filling glovebox

with single/multiple contained glovebox levels for

handling powders of varying potency.

PSL analyse accuracy requirements - delivering

precise weights and catch weights or volumetric

• Fully contained product discharge

• Contained sampling & Heel Recovery system

• Continuous Liner Systems

Containment

Milling and Micronizing

Our contained micronizer mill/air jet mill glovebox

are innovatively designed by expert process

engineers for size reduction of active ingredients.

• Milling process assessment including types of mill,

feeders and product collection

• Full safety review including nitrogen protection

system for dust explosion risks

• Sampling method evaluation including integration

of online particle size analysers

Containment

Sieving & Blending

PSL’s sieving isolators are designed and manufactured to maximum containment standards down to

nanogram level.

• Material flows analysis including drum sizes, weights and transfers

• Half suit design available providing ergonomic advantage

• Can be engineered alone or with integrated process equipment: mills and micronizers, blenders and weighing scales

Containment

Tablets and Capsules

Bespoke high containment retrofit systems for existing capsule filling

machines and tablet presses.

• Swing-out doors with safety interlocks

• Special gloveport retainers

• Contained de-dusting and internal vacuum cleaning system

High Containment Micro Dosing Xcelodose® (from Capsugel):

the Xceloprotect™

Small Scale Acrylic Isolator

Laboratory or QA process steps can be contained within a simple

acrylic glovebox for enhanced visibility and cost-effectiveness

Total Process Solutions

Multiple process steps can be contained

within a single isolator providing a complete

synthesis or formulation suite.

Complete Turn-Key Solution

Containment Testing and Validation

PSL uses a third party industrial hygienist to monitor testing and generate a final OEL test report.

In conjunction with our clients, PSL defines OEL parameters and generate an OEL test protocol

following industry best practice guidelines such as ISPE.

Complete Turn-Key Solution

Glove Integrety Testing System

PSL offers solutions to test and validate the glove integrity of high containment isolators and

gloveboxes.

The new PSL Glove Testing System provides a quick, safe and easy method to test fitted pharma

gloves.

• Easy to use, just unpack, insert and start

the automated measurement

• Superior hole detection

• Manual to fully automated measurement,

with WiFi remote control and RFiD built-in

technology

• Customizable in size and shape, tailored

to any glove type and detection

requirements

PSL Serve

• Aftercare Service

• Preventative maintenance contracts

• Worldwide emergency call out

• Spare parts including standard consumables and recommended spares

Our reputation for reliability is synonymous with the quality of service that we offer.

FILTRATION, DRYING & HIGH CONTAINMENTPOWDER HANDLING SOLUTIONS