Psoriasis: The New SkinParis Fears

Queens University of CharlotteSPAEP I Pittsburgh, PA

Psoriasis

•‘Psora’ means to itch in Greek

•Gain an understanding of the disease, Psoriasis

IntroductionWhat is Psoriasis

BackgroundEpidemiology

Genetics Physiology

Quality of LifeTreatmentsConclusion Questions

Table of Contents

Psoriasis

•Psoriasis, a chronic non-infectious immune-mediated inflammatory skin condition that causes thick red and flaky patches of skin

•Natural Course•5 common types

Questions

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusionQuestionsReferences

Table of Contents

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusion QuestionsReferences

Table of Contents

Psoriasis

•Psoriasis, a chronic non-infectious immune-mediated imflammatory skin condition that causes thick red and flaky patches of skin

•Natural Course•5 common type

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusionQuestions

References

Table of Contents

Plaque*-basic dry, itchy, red skin in common sites Guttate- proceeds after strep throat; numerous red scaly bumpsInverse*- occurs in excess skin folds and soft tissuePustular- small pus filled bumps on whole body or hands and feetErythrodermic- aggressive plaque with pain and wide patches on entire body

Psoriasis

•Mistoken for 150 years• 1700’s to 1800’s Robert

Willian and Jacob Plenck•1841 Ferdinand von

Hebra

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusionQuestionsReferences

Table of Contents

Psoriasis

•7.5-8.5 million •125 million •150,000•<400, >400•Everyone is at risk

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusion QuestionsReferences

Table of Contents

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusionQuestions

References

Table of Contents

•40% increase in risk of contracting Psoriasis with "familial tendency"   •Identical Twins incidence

Psoriasis•Psoriasis triggers•Stress•Little Sun Light•Injury to skin•Medication•Immune system

deficiencies

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusionQuestionsReferences

Table of Contents

PsoriasisIntroduction

What is PsoriasisBackground

EpidemiologyGenetics

PhysiologyQuality of Life

TreatmentsConclusionQuestions

References

Table of Contents

PsoriasisIntroduction

What is PsoriasisBackground

EpidemiologyGenetics

PhysiologyQuality of Life

TreatmentsConclusionQuestionsReferences

Table of Contents

Psoriasis•$1.6 billion to $4.3 billion

dollars•75% believe in negative

impact•Comorbidities

• HIV

• CVD

• Obesity and Alcohol Abuse

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusionQuestions

References

Table of Contents

Psoriasis•Controlled not Cured•Topical treatments•Home remedies•Pills•Alternative treatments

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusionQuestions

References

Table of Contents

Summary• Prevalent in all genders races,

and ages 3-95

• Effects about 125 million people worldwide

• Complex auto-immune inflammatory skin condition which includes, white scaly and raised red lesions

• Triggers include anything from bacterial and viral infection to stress

• The exact schematics to cure this disease are still a mystery

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusionQuestions

References

Table of Contents

QUESTIONS?

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusionQuestionsReferences

Table of Contents

IntroductionWhat is Psoriasis

BackgroundEpidemiology

GeneticsPhysiology

Quality of LifeTreatmentsConclusionQuestions

References

Table of Contents References

• Babu, Hanish. "History of Psoriasis.” General Medicine (suite 101) (2008): n. pag. Web. 17 Jul 2011. http://www.suite101.com/content/history-of-psoriasis-a85546. • Bhosle, Monali J, Amit Kulkarni, Steven R Feldman,

and Rajesh Balkrishnan. "Quality of life in patients with psoriasis." Health and Quality of Life Outcomes 4.35 (2006): Web. 17 Jul 2011. http://www.hqlo.com/content/4/1/35>. • Kurian, Anil, and Benjamin Barankin. "Current

Effective Topical Therapies in the Management of Psoriasis." Skin Therapy Letter 16.1 (2011): 4-7. Web. 26 Jun 2011.http://www.skintherapyletter.com/2011/16.1/2.html.• Schön, Michael P, and W.-Henning Boehncke.

"Psoriasis." N Engl J Med 352. (2005): n. pag. Web. 17 Jul 2011. http://www.nejm.org/doi/full/10.1056/NEJMra041320#t=article.