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Psychiatry -Delirium, Dementia and Amnestic Disorders (Dr.sundiang)

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    Delirium, Dementia andAmnestic Disorders

    Second Year Psychiatry

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    CognitionThe mental process of knowing.

    Includes awareness, perception,reasoning, judgment, memory,language, orientation, conducting

    personal relationships,performing actions and problemsoling.

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    Cognitie !isorders!isruptions in the acts andprocesses inoled in cognition.

    "sually associated withbehaioral symptoms.

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    #istorical $ackground"sed to be classi%ed under&organic mental disorder'.

    "nder !S()I*)T+, classi%edunder

    !elirium, !ementia andmnestic

    and other Cognitie !isorders

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    #istorical $ackgroundIn !S()*, under -eurocognitie

    !isorders

    !elirium retained

    !ementia replace with major and

    minor neurocognitie disordermphasis on decline in functioningrather than memory disturbance

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    reas of Primary

    !isturbance!elirium / leel of consciousnesswith associated impairments in

    memory, judgment, orientationand attention

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    reas of Primary

    !isturbance!ementia / impairment inmemory, language and intellect

    mnestic !isorder / impairmentin memory in the absence ofclouded consciousness andde%cits in other areas ofcognition

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    !eliriumcute onset of disturbance inleel of consciousness and

    0uctuating cognitieimpairments.

    +e0ects response to widespreadaltered cerebral functions.

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    !S()I*)T+ Classi%cation of !elirium!elirium due to a general medicalcondition 1indicate the condition2

    Substance into3ication delirium

    Substance withdrawal delirium

    !elirium due to multipleetiologies 1indicate the etiologies2

    !elirium not otherwise speci%ed

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    pidemiology !elirium#igher prealence and incidencein

    lderly

    (ultiple medical problems

    #ospitali4ed patients especially

    critically ill patients

    Terminally ill patients

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    Clinical 5eatures of

    !eliriumPrimary feature )diminished clarity of

    awareness of the enironment

    1disturbance of consciousness26anguage and other cognitie changes

    Perceptual disturbances

    !isturbance in sleep and wakefulness!isturbance in orientation

    !isturbance in arousal leel

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    Clinical 5eatures of

    !elirium!eelops oer a short period oftime 1hours or days2

    Tends to 0uctuate oer the courseof a day

    5rom history, P or laboratorythere is7are identi%ed condition7sor substance7s as a likely etiology

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    Causes of !eliriumInfections

    (etabolic and endocrine abnormalities

    Intracranial states#ypoperfusion states

    Substance into3ication7withdrawal

    Postoperatie states

    Sensory and enironmental changes

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    aluation of !elirium

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    aluation of !elirium

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    aluation of !elirium

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    (anagement of !elirium5ind cause7s

    Correct or eliminate cause7s

    Supportie therapy,enironmental control

    Pharmacologic agents

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    Course and Prognosis !eliriumfter cause7s remoed symptomsusually recede oer 8 to 9 days.

    Seldom persist beyond : weeks ifcausatie factors are reersibleand remoed.

    ;lder patients and longer durationof delirium longer time to resole

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    !ementia progressie impairment ofmultiple cognitie functions

    occurring in an indiidual withclear consciousness

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    !S()I*)T+ Classi%cation of

    !emential4heimer=s Type

    *ascular !ementia

    !ue to ;ther

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    pidemiology of

    !ementia>? years and older / ?@

    A? years and older / :B@ to B@

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    Causes

    of !ementiaStructural central nervoussystem factors

    *ascular factors#ead traumaSubdural hematoma-ormal)pressure hydrocephalus(ultiple sclerosis

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    Potentially +eersible Causes of

    !ementiaPsychiatric illnesses

    (ajor depressionSubstance dependence

    Systemic/metabolic factors7infectious diseases #ypothyroidism

    #ypercalcemia#ypoglycemia

    Thiamine, niacin, $D:

    de%ciency

    +enal failure#epatic failure(edications

    C-S infections

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    Clinical 5eatures of

    !ementia(ultiple cognitie de%cits

    )memory impairment / inability to learn

    and recall ) apra3ia / impaired ability to carry out

    motor functions

    )agnosia / inability to recogni4e or identify

    objects

    )disturbance in e3ecutie functioning /planning, organi4ing, seEuencing,

    abstracting

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    Clinical 5eatures of

    !ementia!ecline from a higher leel offunctioning

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    aluation of !ementia

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    Treatment and (anagement of

    !ementiaIdenti%cation and correction of

    possible cause

    nironmental manipulation toreorient patient

    (ultiple interentions inoling

    family and patientPharmacological management when

    appropriate

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    Course and Prognosis of !ementia5actors which in0uence course and

    prognosis

    )etiology )time span between onset and start of

    treatment

    )presence of comorbid psychiatric

    symptoms

    )leel of psychosocial support

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    !elirium s. !ementia

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    !epression s. !ementia

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    mnestic !isordercharacteri4ed by a lost ofmemory due to eFects of a

    general medical condition orpersisting eFects of a substance

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    !S()I-)T+ Classi%cation of

    mnestic !isorderamnestic disorder due to a general

    medical condition

    substance)induced persistingamnestic disorder

    not otherwise speci%ed

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    Clinical 5eatures of mnestic

    !isorderdeelopment of memory impairment

    manifested by inability to learn newinformation and to recall preiously learned

    informationrepresents a decline from a preious leel of

    functioning

    does not occur e3clusiely in the course of adelirium or dementia

    presence of a general medical condition ofeidence of persisting eFect of a substance

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    Causes of mnestic

    !isorder

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    Treatment and (anagement of

    mnestic !isorder!irected at identifying andcorrecting underlying cause

    Psychosocial interention

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    Course and Prognosis of

    mnestic !isorders!epends on underlying cause

    Transient global amnesia and

    amnestic disorder due to headtrauma hae better outcomes

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    +eferenceSadock $G, Sadock, *. . In Haplan and

    Sadock=s Synopsis of Psychiatry. Philadelphia,P 6JJK :BB9, 8DL)8?B.

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    (+(I-< S6(TMMM


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