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Autism spectrum disorder and mental health Autism spectrum disorder: a lifespan perspective To be published, Jessica Kingsley, 2010 Can the world afford autistic spectrum disorder? Published Jessica Kingsley, 2009 www. dilemmas.org
Digby Tantam, Universities of Cambridge and Sheffield Dilemma Consultancy
9.30 Introduction 9.45 to 10.15 where I work, what I am looking for from the day 10.15 to 10.45 common mental health problems in ASD/ how to
recognize them/ risks 10.45-11 break 11.00 common emotional and externalizing problems in ASD/ how
to recognize them/ psychological/ medical treatments 12.30-1.15 Lunch. 1.15-1.45 work in small groups, select one challenging case where
there was never an additional diagnosis, what mental health diagnosis or category might have been applicable, consider how this would have changed management (if at all)
1.45-3 How do these mental health problems link with ASD 3-3.15 break. 3.15-4.15 answer questions and feedback
Disorder (Seedat et al, 2009) %affected (95% confidence
interval)
Social anxiety 29.2% (13.2% to 45.1%)
ADHD 28.2% (13.3% to 43%)
Opposi>onal defiant disorder 28.1% (13.9% to 42.2%)
Tic disorder, tricho>llomania,
enuresis, encopresis
Mini-SPIN (Connor et al, 2001)
• ‘‘Fear of embarrassment causes me to avoid doing things or speaking to people,’’
• ‘‘I avoid activities in which I am the center of attention,’’
• ‘‘Being embarrassed or looking stupid are among my worst fears.’’
Not at all Extremely 0 1 2 3 4 5
WHO screening questions for ADHD
• How often does he/she have trouble finishing a task or project once the challenging parts have been done?
• How often does he/she have difficulty getting things in order when he/she has to do a task requiring organisation?
• How often does he/she have problems remembering appointments or obligations?
• When he/she has a task that requires a lot of thought, how often does he/she avoid or delay getting started?
• How often does he/she fidget or squirm with his/her hands or feet when sitting down for a long time?
• How often does he/she seem to be overly active and compelled to do things, like he/she was being driven by a motor?
1. Rarely 2. Occasionally 3. Frequently as a child 4. Frequently as a child
• as a child but has now stopped and still persists
% people with ASD and with this disorder
Hu5on et al N=135
My clinic sample N=490
Balfe et al N=78
Hofvander et al N=122
Weighted mean %
ADHD 43 43.00 Anxiety 16 42 47 50 39.40 Depression 25 30 17.68 Obsessive-‐compulsive disorder 4 14 8.97 Substance misuse 4 16 4.74 Somatoform disorder 41 5 4.62 Bipolar disorder 1 3.2 8 3.25 Panic disorder 30 2.84
Brief psychosis 3.4 2 2.32 Schizophrenia 3 3 2.23 EaSng disorder 5 0.74 Catatonia 1 0.59 Delusional disorder 1 0.15
OCD
• Obsession: recurrent, intrusive thought. Not simply worry. anxiety
• Compulsion: Action. anxiety • Person realizes irrationality. Ego-dystonic
experience. Attempt at thought supression • Lifetime prevalence: 2.5% in all cultures
OCD: Course
• 75% have both obsessions and compulsions • Sudden onset after stress • 1/3 worsen; 1/3 improve; 1/3 stay ill • 1/3 have Major Depression • Suicide risk
PTSD
• Must experience extreme trauma • Re-experience trauma • Avoid reminders • Numbing • Persistent hyper-arousal • Dissociation
Psychosis: illness features • Positive symptoms"
• Hallucinations"• Disorganized thinking"• Delusions"• Movement disorder"
• Negative symptoms in schizophrenia"• Decline in social and occupational functioning "• Reduction of nonverbal expression (ʻflattening of
affectʼ)"• Partial mutism (poverty of speech)"
Psychosis: the affected person may: "
• Talk to himself "• See things"• Gesture to himself "
Psychosis: the affected person may: "
• Become confused in their speaking"• Appear muddled"• Dress in layers in any weather "• Fail to bathe and get a haircut "• Gain an odd interest in ordinary things (like
religion) "
Psychosis: the affected person may: "
• May even believe he is God "• See things"• Feel people are out to get them "• Believe in all sorts of conspiracies "• Have ideas that no amount of evidence to
the contrary can dislodge
Psychosis: the affected person may: "
• May become restless and over-active for no reason"
• Become slowed, and sometimes immobile for long periods with long pauses in speaking"
• Limbs may seem as if made of soft bendable metal
Psychosis: the affected person may: "
• Be unable to work "• Stop talking or greatly reduce conversation "• Appear lazy, unmotivated and uninterested "• May look like he has dementia "• Lose the ability to get and keep friends "• Be tense
• Are voices always hallucinations? • Are weird ideas always delusions? • Is incoherent speech always thought
disorder? • When is thought insertion, rumination?
• physical agitation and/or anger • expressed intent to kill or take revenge • identification of specific victim(s) • psychotic symptoms, especially 2nd person
command hallucinations to commit violence • persecutory delusions • disinhibition caused by traumatic brain injuries
and other central nervous system dysfunctions • current use of alcohol or other drug
• living under circumstances of violence • environmental access to guns or other lethal
weapons • membership of violent peer group • poor impulse control; risk taking or reckless
behaviour • statements to others of intent to inflict harm • History of violence or antisocial acts
Type of medication
Ratio of improved
to no effect or worse
Number of children
trying this treatment (% of
sample)
Miscellaneous GI medication 4.00 10 (2%)
Miscellaneous herbal medication 3.33 13 (2.7%)
Atypical antipsychotics 2.08 80 (16.7%)
Anxiolytics 2.00 12 (2.5%)
Stimulants 1.80 172 (35.9%)
Mood stabilizers 1.80 70 (14.6%)
Chelation 1.60 32 (6.7%)
GF and/or CF dietb 1.52 155 (32.4%)
Antidepressants 1.31 136 (28.4%)
Other dietc 1.19 54 (11.3%)
Miscellaneous other medication 1.17 13 (2.7%)
Type of intervention
Ratio of improved to
no effect or worse
Number of children trying this
treatment (% of sample)
Applied behavior analysis (ABA) 3.76 225 (47.0%)
Social skills training 3.05 244 (50.9%)
Picture exchange system (PECS) 2.88 231 (48.2%)
TEACCH 2.86 88 (18.4%)
Positive behavioral support 2.82 233 (48.6%)
Sensory Integration 2.79 255 (53.2%)
Occupational therapy 2.77 361 (75.4%)
Physical therapy 2.68 146 (30.5%)
Speech therapy 2.53 403 (84.1%)
Early intervention services 2.39 331 (69.1%)
Social stories 2.33 197 (41.1%)
Floor time 2.10 129 (26.9%)
What are the real drug effects? • Reducing severe depression:
Antidepressants • Reducing positive symptoms:
• Antipsychotics • Reducing anxiety
• ?SSRIs
• Reducing over-activity and increasing response control: • Stimulants
• Reducing mood fluctuations • Lithium and anticonvulsants
Choose a drug with least side effects
Psychological treatments
• Some specific anxiety reduction with cognitive methods
• Some specific improvement of mood with behavioural activation
• Otherwise there is no difference in modalities except
• Flavour and values • Main outcome determinant is focus
Parental or informal carer involvement
• Reduces depression, and therefore critical comments, and hostility
• Reduces externalizing behaviour in client • ‘oppositional behaviour’ • Conduct disorder • Bloody mindedness
WHAT IS ASD?
• Impaired nonverbal communication (expression and interpretation) is the sine qua non • There is a low bandwidth ‘interbrain connection’ • Often associated with other learning difficulties and disconnection problems • People with AS are more susceptible to bullying, to emotional disorder, and therefore have worse quality of life than others with ASD • Understanding the experience of having ASD is key to more successful coping strategies
Enmeshment
• Anxious attachment • Caused by threat • Identity threat to family system and work with
it, and not against it • Define hostility as frustration • Rage and anger as fear
The power of power
• The rage that conceals impotence, or incapacity is inversely proportional to popularity and ‘social influencing power’
• Outrage conceals this • In men, anger often conceals shame
Sacar, Bradford 22 Oct 09
From The autistic spectrum OpenLearn LabSpace
Sacar, Bradford 22 Oct 09
Features of nonverbal inexpressiveness
• Reduction of expression or occasionally idiosyncratic expressions such as unusual prosody, facial mannerisms
• Affects all channels • Voluntary signals e.g. social smiles
unaffected • Is not the commonest cause of gaze
avoidance, in fact may result in staring
Sacar, Bradford 22 Oct 09
Feature of nonverbal inexpressiveness
• Reduction of expression or occasionally idiosyncratic expressions such as unusual prosody, facial mannerisms
• Affects all channels • Voluntary signals e.g. social smiles
unaffected
Sacar, Bradford 22 Oct 09
Atypical Asperger syndrome: a disorder of nonverbal interpretation
• Primary abnormality is lack of empathy, partly due to failure of non-verbal interpretation (‘face blindness’)
• Ability to make relationships but not to keep them
• Lack of empathy may lead to antisocial behaviour, but greater problem is lack of persuasiveness and ‘social influencing power’
Picture from the film, “Ripley’s game” starring Matt Damon as Ripley
Sacar, Bradford 22 Oct 09
Knowing about the world using non-verbal cues
Who is being shot?
Terrorists or partisans?
Sacar, Bradford 22 Oct 09
Is Asperger syndrome the future?
Bram Cohen, founder BitTorrent, and self diagnosed Aspie
Owen Thor Walker apointed to TelstraClear, who previously wrote code enabling a hacker group to steal £13.9M from bank accounts