History of Genetics
Father of modern genetics
Studied pea plants
Found that plants that were true-breeding (able to pollinate themselves) produced offspring identical to themselves
Found that when plants reproduced (crosspollination) with other plants that offspring showed a mix of characteristics of both parents
Gregor Mendel
Seed Shape
Flower Position
Seed Coat
ColorSeed Color
Pod Color
Plant Height
Pod
Shape
Round
Wrinkled
Round
Yellow
Green
Gray
White
Smooth
Constricted
Green
Yellow
Axial
Terminal
Tall
Short
Yellow Gray Smooth Green Axial Tall
Section 11-1
Figure 11-3 Mendel’s Seven F1
Crosses on Pea Plants
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Section:
Mendel’s Principles Inheritance of biological characteristics is
determined by genes. Genes are passed from
parents to offspring.
Some forms of a gene may be dominant and
others may be recessive.
Organisms have 2 alleles for each gene
(1 from each parent). These alleles will
segregate during gamete formation.
Alleles for different genes usually
segregate independently from one another.
Mendel’s Laws of InheritanceLaw of Dominance: In heterozygous genotypes,
dominant alleles (capital letters) hide recessive alleles
(lowercase letters) when both are inherited by an
organism. (Yy means the dominant trait will show up
in the phenotype)
Mendel’s Laws of Inheritance
The Law of
Segregation
(separation):
Each organism
has 2 alleles for
a gene. Only
one allele from
each gene pair
will be passed on
to the offspring.
Polygenic Traits
Traits that are controlled by more than 1
gene.
Ex. Human eye color (at least 6 genes)
Ex. Human skin color (at least 4 genes)
Causes a wide variety of phenotypes.
In the case of skin color, this is what
causes the great variety of skin tones.
Genotype vs. Phenotype Genotype
The combination of alleles for a given trait
(the genetic make up)
Ex. TT, Tt, tt
Phenotype
The physical appearance caused by the
interaction of alleles
In general, if a dominant allele is present
then the dominant condition will be shown
Ex. Tall, Short
Genotype vs. Phenotype
Rr
Red color
Wavy hair
bb
Tall
Genotype
Phenotype
Phenotype
Genotype
Phenotype
Alleles
Homozygous = individual with 2 of the
same allele for a given trait
Ex. TT, RR (homozygous dominant)
tt, rr (homozygous recessive)
Heterozygous = individual with 2
different alleles for a given trait
Ex. Tt, Rr, Ww
Allele Practice
TT
Rr
Ww
AA
jj
Homozygous dominant
Heterozygous
Heterozygous
Homozygous dominant
Homozygous recessive
Punnett Squares
A Punnett square illustrates how the
parents’ alleles might combine in
offspring.
The top of the Punnett Square are
usually the male’s alleles, the side of the
Punnett square shows the female’s
alleles for the trait
Punnett Squares Examples
1. Cross a homozygous
dominant tall plant
with a homozygous
recessive short plant.
What letters would
you use to represent
this cross?
Dominant trait = tall
Recessive trait = short
T =
t =
tallshort
What is the genotype of a homozygous
dominant tall plant?
Genotype
% TT
% Tt
% tt
TT
TT x tt
What is the genotype of a homozygous
recessive short plant? tt
t t
T
T
Phenotype
% tall
% shortTt Tt
Tt Tt
0
100
0
0
100
2. Cross a heterozygous brown haired rabbit with a homozygous white haired rabbit.
What letters would you use to represent this
cross?
Dominant trait = brown hair
Recessive trait = white hair
B =
b =
brown
white
What is the genotype of a heterozygous
brown haired rabbit?
Genotype
% BB
% Bb
% bb
Bb
Bb x bb
What is the genotype of a homozygous
white haired rabbit? bb
b b
B
b
Phenotype
% brown
% whitebb bb
Bb Bb
0
50
50
50
50
3. Cross a homozygous dominant longhaired guinea pig with a heterozygous guinea pig.
What letters would you use to represent this
cross?
Dominant trait = long hair
Recessive trait = short hair
L =
l =
long
short
Now, you try this one!
What is the genotype of a homozygous
dominant long haired guinea pig? LL
What is the genotype of a heterozygous
long haired guinea pig? Ll
What is the phenotype of the
heterozygous guinea pig?
long hair