PureHeartTM

Barry W. Ritz, PhDInstitute for Functional Medicine

May 30, 2013

Screening + Supplements = SuccessTM

“Beyond Lipids”• Underlying factors

• Lipid balance• Blood flow, vascular

function• CoQ10 status• Glucose metabolism• Oxidative stress

• Co-support• Medications• Supplements• Lifestyle

www.pureheartprotocol.com

Cleveland HeartLab Roadmap

Step 1 Step 2 Step 3Contact

Cleveland HeartLab®

Determine Clinical Goals-algorithms

www.pureheartprotocol.com

Choose from Pure

Encapsulations® Supplements

Retest after 3-6 months

Step 1 Step 2 Step 3Contact Cleveland

HeartLab®Determine Clinical

GoalsChoose from Pure Encapsulations®

Supplements

Myeloperoxidase (MPO): Proprietary marker for arterial wall health.

≥ 480 pmol/L

Support healthy glucose metabolism*

Alpha Lipoic Acid w/GlucophenolTM, Metabolic Xtra

Support healthy CoQ10 levels*

SR-CoQ10 w/PQQ or Ubiquinol VESIsorb®

Support antioxidant defense*

ResCu-SRTM or Resveratrol VESIsorb®

*These statements have not been reviewed by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

Cleveland HeartLab Roadmap

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Pure Encapsulations® Supplements•R

esearch-based•P

rofessionally dosed•H

ypoallergenic•F

ormulated for sensitive individuals•A

voiding:

Common allergens, coatings, shellacs, binders, fillers, excipients, artificial flavors, artificial sweeteners, or colors

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Healthy glucose metabolism*

• Berberine HCl, alpha-lipoic acid, resVida (trans-resveratrol), Zychome (Cr dinicocysteinate)

• Insulin receptor function (AMPK, SIRT1) and glucose homeostasis*

Metabolic Xtra

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Healthy glucose metabolism*

Alpha Lipoic Acid w/ Glucophenol

Insulin sensitivity and glucose clearance*

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Healthy glucose metabolism**

*

Glu

cose

Up

take

Infl

amm

atio

n

Res

po

nse

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Healthy CoQ10 levels*

• Microactive® slow release CoQ10• PQQ (pyrroloquinoline quinone)• Complementary mechanisms in

cardioprotection and cognitive/neuronal health*

Extended Release

Pla

sma

Co

Q10

(m

cg/m

L)

SR-CoQ10 with PQQ

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Healthy CoQ10 levels*

• Ubiquinol- Active antioxidant form of CoQ10

• Self-assembling colloidal delivery system for maximum absorption

Ubiquinol VESIsorb

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Healthy CoQ10 levels*

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Antioxidant defense*• Microactive® high

bioavailability, sustained release resveratrol and curcumin- consistent delivery

• Exclusive, proprietary formula

ResCu-SRTM

Resveratrol

Curcumin

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Antioxidant defense*

Payette C et al. Sex differences in postprandial plasma tumor necrosis factor-α, interleukin-6, and C-reactive protein concentrations. Metab Clin Exp (2009) 58:1593-1601

Res

Cu

-SR

TM

Screening + Supplements = SuccessTM

•Easy as 1-2-3

•Please visit our microsite for more information

•ResCu-SR

www.PureHeartProtocol.com