388
Reagent Guide8th Edition
Bioscience& Analytical Science
We have reviewed our product line-ups and organized them according to the research areas of bioscience and analytical science. We hope that this reagent guide will be of assistance to your research and development laboratories.However, this guide is not an inclusive list of all the reagents we deal in. Please be sure to look up our catalog and visit our website as well to remain updated on the latest information in the various fi elds of your interest.
www.TCIchemicals.com
Bioscience
Nucleosides, Nucleotides, Nucleic Acids Nucleosides, Nucleotides, Nucleic Acids ...................1Amino Acids, Peptides, Proteins Amino Acids .................................................................. 17 Peptides ......................................................................... 52 Enzymes ........................................................................ 62Sugars Sugars ............................................................................ 63 Lectin, Fucose Specifi c ............................................... 96 An Enzyme that Adds Whole Sugar Chains without Breaking Down Products .......................................... 97
An Enzyme Transfers the Intact Oligosaccharides ...................................................................................100 Anti-Glyco Antibodies ................................................103Lipids Lipids ............................................................................106Other Natural Products and Derivatives Terpenes ......................................................................114 Steroids ........................................................................126 Phenylpropanoids & Aromatic Polyketides .............136 Alkaloids ......................................................................148 Polyamines ..................................................................157 Porphyrins ....................................................................163 Vitamins .......................................................................165Pharmacology, Medicinal Chemistry Pharmaceutical Ingredients for Research and Experimental Use ....................................................170
Drug Delivery System (DDS) ....................................212 Preparing Animal Disease Model ............................217Cell Biology, Regenerative Medicine Epigenetics ..................................................................220 Regenerative Medicine Research ............................222 Reactive Oxygen Species (ROS), Reactive Nitrogen Species (RNS), Oxidative/Nitrosative Stress Research ...................................................................225
Inhibitors ......................................................................233Biochemistry, Molecular Biology Bioconjugation ............................................................234 Fluorometry & Fluorescent Imaging .........................241 Antibodies ....................................................................247 Staining ........................................................................254 Substrates for Enzymatic Detection ........................257 Reagents for Electrophoresis ...................................261 Surfactants ..................................................................264 Protein Denaturation Reagents ................................265 Non-detergent Sulfobetaines (NDSB) .....................266 Preservatives ...............................................................267 Buff ers ..........................................................................268Phytochemistry Plant Hormones ..........................................................270 Phytochemicals ..........................................................274
Analytical Science
GC GC Derivatizing Reagents ........................................276 Standard Materials for GC ........................................279HPLC Labeling Reagents for HPLC ....................................281 Ion-Pair Reagents for HPLC .....................................290 Solvents for HPLC & Spectrophotometry ...............293 Chromatography Columns for HPLC .......................294TLC TLC Stains ..................................................................301NMR NMR Spectrometry .....................................................302 Enantiomer Excess & Absolute Confi guration Determination ...304MS Derivatization Reagents for Mass Spectrometry ...311 Standards for Mass Spectrometry & Matrix Materials ....316ESR ESR Spectrometry ......................................................318Indicator pH Indicators ...............................................................320 Ion Association ...........................................................322 Chelating Reagents ....................................................323Reference/Standard Substances Food Colors by Food Sanitation Law in Japan .....329 Food Color Testing Solutions ...................................330 Reference Materials Certifi ed by The Japan Petroleum Institute ..................................................332
Abbreviations ................................................................334The physical properties of the typical organic solvents / Freezing mixtures .................................................338
Preparation of Reagents and Solutions ...................339Parent Structures & Biosynthesis of Natural Products ....341
INDEX ...........................................................................357
TCI International Offi ces .............................................368TCI Distributors ............................................................369
If you are looking for products in the fi eld of Synthetic Organic Chemistry & Materials Chemistry, please see below.
Reagent Guide8th EditionSynthetic Organic Chemistry & Materials ChemistrySynthetic Organic ChemistryExample :Asymmetric Organocatalysts / Cross-coupling Reaction Using Transition Metal Catalysts / Condensation & Active Esterifi cation etc.Materials ChemistryExample :Reagents for Solar Cell Research / Photochromic Compounds / OLED Materialsetc.
Contents
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
1This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
Nucleosides, Nucleotides, Nucleic Acids
Genetic information is stored in DNA as combinatorial codes held in nucleosides and nucleotides, in which form it is passed from parents to their off spring. Analogs of nucleosides and nucleotides are used clinically as medicinal agents such as reverse transcriptase inhibitors. Therefore, the preparation and development of these species as eff ective, selective and nontoxic antiviral and antitumor agents has been the subject of intense research.1)In addition to this, the development of Polymerase Chain Reaction (PCR) methodology has brought a dramatic change and rapid development in studies of DNA. At the current time the draft version in decoding and mapping human genome has been almost completed, and the functional analyses of genome and analyses of Single Nucleotide Polymorphism (SNP) are being vigorously pursued. Discovery of the RNAi process has facilitated the fast progression of studies of RNA. At the same time, chemically synthesized oligoDNA and oligoRNA have been studied as potential antisense DNAs, siRNAs and DNA aptamers, as oligonucleotide therapeutic agents, primers for PCR method, and elements of DNA computers.
Nucleosides and their AnalogsNucleosides are glycosylamines made by attaching a nucleobase to a ribose or 2'-deoxyribose, which can be phosphorylated producing nucleotides. Nucleoside analogues are an established class of clinically useful medicinal agents possessing a wide range of antiviral and anticancer activities. Consequently, extensive modifications have been made to both the heterocyclic base and the sugar moiety. Some representative examples of these are 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) developed by Elion in 1977, which shows antiviral activity; 3'-azido-3'-deoxythymidine (AZT) discovered by Mitsuya et al. in 1985 and used for the treatment of HIV infection; and cytosine -D-arabinofuranoside (cytarabine) approved by the FDA in 1969 and which has been shown to display a range anticancer activities. In addition, modifi ed nucleosides such as 2'-deoxy-5-methylcytidine are ubiquitous in living systems, and their functions have received due attention from the scientifi c community.2)Protected nucleosides, in which reactive amino and hydroxyl groups have been masked, e.g. N 6-
benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine (Bz-DMT-dA), have been used for chemical synthesis of DNA and RNA.
Pyrimidine Nucleosides
Product No. Product Name Unit SizeA2528 Acadesine 50mgA2073 1-(3,5-Anhydro-2-deoxy--D-threo-pentofuranosyl)thymine 5g 25gA2431 2,2'-O-Anhydro-5-methyluridine 1gA2356 1--D-Arabinofuranosyluracil 1g 5gA2033 5-Azacytidine 100mg 1gA2232 5-Aza-2'-deoxycytidine 20mg 100mgA0559 6-Azauridine 10mgA2052 Azidothymidine 1g 5gB3094 N 4-Benzoylcytidine 1g 5gB3102 N 4-Benzoyl-2'-deoxycytidine 100mg 1gB3087 N 4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine 1g 5gB3631 N 4-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine 1g 5gB3404 Brivudine 100mg 1gB1575 5-Bromo-2'-deoxyuridine 1g 5gB0666 5-Bromouridine 100mg 1gC2878 Capecitabine 1g 5gC2207 2,2'-O-Cyclocytidine Hydrochloride 1g 5gC2208 2,2'-O-Cyclouridine 5g 25gC2035 Cytarabine 5gC0522 Cytidine 1g 5g 25gC0525 Cytidine Sulfate 100mg 1gD3583 2'-Deoxycytidine 1g 5gD0048 2'-Deoxycytidine Hydrochloride 5g 25gD3614 2'-Deoxy-2'-fl uorocytidine Hydrate 1gD3642 2'-Deoxy-5-fl uorocytidine 1g 5gD4342 5'-Deoxy-5-fl uorocytidine 1g 5g
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical S
cience
2 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Nucleosides, Nucleotides, Nucleic Acids
Product No. Product Name Unit SizeD3615 2'-Deoxy-2'-fl uorouridine 1g 5gD2235 2'-Deoxy-5-fl uorouridine 100mg 500mg 1gD3579 5'-Deoxy-5-fl uorouridine 1g 5gD4220 2'-Deoxy-5-(hydroxymethyl)cytidine 50mg 200mgD3610 2'-Deoxy-5-methylcytidine 100mg 500mg 5gD0060 2'-Deoxyuridine 1g 5g 25gD3566 5'-O-(4,4'-Dimethoxytrityl)thymidine 5g 25gE1057 5-Ethynyl-2'-deoxyuridine 50mg 200mgD4200 Fialuridine 10mgF0534 5-Fluorocytidine 1gF0636 5-Fluorouridine 1g 5gG0367 Gemcitabine Hydrochloride 100mg 1gI0258 Idoxuridine 1g 5g 25gI0882 5-Iodo-2'-deoxycytidine 1gL0217 Lamivudine 100mg 1gM1931 5-Methylcytidine 1gM2317 2'-O-Methylcytidine 200mg 1gM1405 5-Methyluridine 1g 5g 25gM2290 2'-O-Methyluridine 1g 5gM2399 Mizoribine 50mg 250mgR0077 Ribavirin 100mg 500mgD3580 Stavudine 1g 5gF0635 Tegafur 5g 25gT0233 Thymidine 1g 5g 25gT2549 2',3',5'-Tri-O-acetyluridine 5g 25gT2511 Trifl uorothymidine 100mg 1gU0020 Uridine 5g 25gD3581 Zalcitabine 1gZ0022 Zebularine 200mg 1g
A2528
O
OH
NHO
OH
NC NH2
O
NH2
A2073
O
NO
HN
O
O
CH3
A2431
O
OH
HO N
N
O
O
CH3
A2356
O
OH
HONHO
HN
O
O
A2033
O
OH
NHO
OH
NN
O
NH2
A2232
O
OH
NHO
NN
NH2
O
A0559
O
OH
NHO
OH
N
HN
O
O
A2052
O
N3
NHO
HN
O
O
CH3
B3094
O
OH
HO N
N
NH C
O
O
OH
B3102
O
OH
HO N
N
NH C
O
O
B3087
O
OH
O N
N
NH C
O
C
OCH3
OCH3O
B3631
O
O
NO
OH
N
O
NH CO
SiOSi
(CH3)2CH CH(CH3)2
(CH3)2CH(CH3)2CH
B3404
O
OH
NHO
HN
O
O
Br
B1575
O
OH
NHO
HN
O
O
Br
B0666
O
OH
NHO
OH
HN
O
O
Br
C2878
O
OH
H3C N
N
NH
O
F
OH
C O(CH2)4CH3
O
C2207
O
OH
HO N
N
NH
HCl.
O
C2208
O
OH
HO N
N
O
O
C2035
O
OH
HONHO
N
O
NH2
C0522
O
OH
HO N
N
NH2
O
OH
Bioscience
Analytical Science
3This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
Nucleosides, Nucleotides, Nucleic Acids
C0525
O
OH
HO N
N
NH2
O
OH
H2SO4.
2
D3583
O
HO N
N
NH2
O
OH
D0048
O
OH
HO N
N
NH2
O
HCl.
D3614
O
OH
HO N
N
NH2
O
F
xH2O.
D3642
O
OH
HO N
N
NH2
O
F
D4342
O
OH
H3C N
N
NH2
O
F
OH
D3615
O
OH
HO N
HN
O
O
F
D2235
O
OH
HO N
HN
O
O
F
D3579
O
OH
H3C N
HN
O
O
F
OH
D4220
O
OH
NHO
NCH2OH
O
NH2
D3610
O
OH
HO N
N
NH2
O
CH3
D0060
O
OH
HO N
HN
O
O
D3566
O
OH
O N
HN
O
C
OCH3
O
CH3
CH3O
E1057
O
OH
NHO
HNC
O
O
CH
D4200
O
OH
F NHO
HN
O
O
I
F0534
O
OH
HO N
N
NH2
O
OH
F
F0636
O
OH
HO N
HN
O
O
OH
F
G0367
O
OH
FHO
N
N
F
HCl.O
NH2
I0258
O
OH
NHO
HN
O
I
O
I0882
O
OH
HO N
N
NH2
O
I
L0217
S
O
OHN
N
O
NH2
M1931
O
OH
NHO
OH
N
O
NH2
CH3
M2317
O
OH
NHO
N
O
NH2
OCH3
M1405
O
OH
NHO
OH
HNCH3
O
O
M2290
O
OH
NHO
HN
O
O
OCH3
M2399
O
OH
NHO
OH
NC NH2
O
OH
R0077
O
OH
NHO
OH
N
NC NH2
O
D3580
O
HO N
HN
O
O
CH3
F0635
O
N
HN
O
O
F
T0233
O
OH
NHO
HN
O
O
CH3
T2549
O
OAc
NAcO
HN
O
OAc
O
T2511
O
OH
NHO
HN
O
CF3
O
U0020
O
OH
NHO
OH
HN
O
O
D3581
O
HO N
N
NH2
O
Z0022
O
OH
NHO
N
O
OH
Purine Nucleosides
Product No. Product Name Unit SizeA1915 Acyclovir 1g 5g 25gA2414 Adefovir Dipivoxil 100mg 1g
Bioscience
Analytical S
cience
4 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Product No. Product Name Unit SizeA0152 Adenosine 5g 25g 100gA2135 2-Aminoadenosine 5g 25gA2054 2-Amino-6-chloropurine Riboside 1g 5gA2739 9--D-Arabinofuranosylguanine Hydrate 10mg 50mgB3093 N 6-Benzoyladenosine Hydrate 1g 5gB3101 N 6-Benzoyl-2'-deoxyadenosine Hydrate 100mg 1gB3103 N 6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine 100mg 1gB4001 8-Bromo-2'-deoxyguanosine 200mg 1gB4002 8-Bromoguanosine Hydrate 1g 5gC2192 2-Chloroadenosine Hydrate 100mg 1gC2206 6-Chloropurine Riboside 1g 5gC2499 Cladribine 50mgC2500 Clofarabine 20mg 100mgC2815 Cordycepin Hydrate 25mg 100mgC2689 Cordycepin 25mgD4137 2'-Deoxyadenosine Anhydrous 5gD0046 2'-Deoxyadenosine Monohydrate 5g 25gD0052 2'-Deoxyguanosine Hydrate 1g 5g 25gD3584 2'-Deoxyinosine 1g 5gB3460 N 6-Dibenzoyladenosine 2',3'-Dibenzoate 100mg 1gD4228 N 6,2'-O-Dibutyryladenosine 3',5'-Cyclic Monophosphate Sodium Salt 25mgD4292 5,6-Dichlorobenzimidazole 1--D-Ribofuranoside 100mg 1gD3066 Didanosine 100mg 500mgD3065 2',3'-Dideoxyadenosine 100mgD4256 Diethyl [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonate 1g 5gF0842 Famciclovir 500mg 5gF0656 2-Fluoroadenosine 200mg 1gG0315 Ganciclovir Hydrate 5g 25gG0171 Guanosine 5g 25g 100gH1290 9-(2-Hydroxyethyl)adenine 5g 25gI0037 Inosine 25g 500gI0759 2-Iodoadenosine 200mg 1g 5gI0700 N 2-Isobutyryl-2'-deoxyguanosine 100mg 1gI0697 N 2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine 1g 5gI0699 N 2-Isobutyrylguanosine Monohydrate 100mg 1gI0702 2',3'-O-Isopropylideneadenosine 5g 25gI0703 2',3'-O-Isopropylideneguanosine 5gI0704 2',3'-O-Isopropylideneinosine 5gM2291 2'-O-Methyladenosine 1gM2318 2'-O-Methylguanosine Hydrate 200mg 1gO0401 8-Oxoadenosine 200mg 1gP2164 Penciclovir 200mg 1gT2690 2',3',5'-Tri-O-acetyl-2-amino-6-chloropurine Riboside 1gT2691 2',3',5'-Tri-O-acetyl-6-chloro-2-iodopurine Riboside 1g 5gT2692 2',3',5'-Tri-O-acetylguanosine 1g 5gV0111 Valacyclovir Hydrochloride Hydrate 100mg 1gV0098 Vidarabine Monohydrate 1g 5gX0008 Xanthosine Dihydrate 100mg
A1915
HN
N N
N
O
H2N
CH2OCH2CH2OH
A2414
N
N N
N
CH2CH2OCH2
NH2
P
OOCH2O
OCH2O
C
C
O
C(CH3)3
O
C(CH3)3
A0152
O
OH
HO
OH
N
N N
N
NH2
A2135
O
OH
NHO
OH
N
N
N
NH2
NH2
A2054
O
OH
NHO
OH
N
N
N
NH2
Cl
A2739
O
OH
HONHO
N
N
NH
O
NH2
xH2O.
B3093
O
OH
HO
OH
N
N N
N
NH C
O
xH2O.
B3101
O
OH
HO
N
N N
N
NH C
O
xH2O.
B3103
O
OH
O
N
N N
N
NH
C
OCH3
CH3O
C
O
B4001
O
OH
NHO
N
N
NH
O
NH2Br
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical Science
5This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
B4002
O
OH
NHO
N
N
NH
O
NH2Br
OHxH2O.
C2192
O
OH
HO
OH
N
N N
N
NH2
xH2O.
Cl
C2206
O
OH
HO
OH
N
N N
N
Cl
C2499
O
OH
HO
N
N N
N
Cl
NH2
C2500
O
OH
FHO
N
N N
N
NH2
Cl
C2815
O
HO
OH
N
N N
N
NH2
xH2O.
C2689D4137
O
OH
NHO
N
N
N
NH2D0046D0052
O
OH
HO
N
N N
NH
O
NH2
xH2O.
D3584
O
OH
HO
N
N N
NH
O
B3460
O
OBz
HO
N
N N
N
NBz2
OBz
D4228
O
O
NO
N
N
N
HN
O
CH3
O
O
CH3POONa
D4292
O
OH
NHO
OH
N
Cl
Cl
D3066
O
HO
N
N N
NH
O
D3065
O
HO
N
N N
N
NH2
D4256
N
N N
N
CH2CH2OCH2
NH2
P
OOCH2CH3
OCH2CH3
F0842
N
N N
N
CH2CH2CH
H2NCH2O
CH2O
C
C
O
CH3
O
CH3
F0656
O
OH
HO
OH
N
N
N
N
NH2
F
G0315
HN
N N
N
O
H2N
CH2OCHCH2OHCH2OH
xH2O.
G0171
O
OH
HO N
OH
N
N
NH
O
NH2
H1290
N
N N
N
CH2CH2OH
NH2
I0037
O
OH
NHO
OH
N
N
NH
O
I0759
O
OH
HO
OH
N
N N
N
NH2
I
I0700
O
OH
NHO
N
N
NH
O
NH
CCH
OCH3CH3
I0697
O
OH
NOC
OCH3
OCH3
N
N
NH
O
CCH
OCH3CH3
NH
I0699
O
OH
NHO
OH
N
N
NH
O
NH
C CH
OCH3CH3
H2O.
I0702
O
O
NHO
O
CH3 CH3
N
N
N
NH2
I0703
O
O
NHO
O
CH3 CH3
N
N
NH
NH2
O
I0704
O
O
NHO
O
CH3 CH3
N
N
NH
O
M2291
O
OH
NHO
N
N
N
NH2
OCH3
M2318
O
OH
NHO
N
N
NH
O
OCH3
NH2
xH2O.
O0401
O
OH
NHO
HN
N
N
NH2
O
OH
P2164
HN
N N
N
O
H2N
CH2CH2CHCH2OH
CH2OH
T2690
O
OAc
AcO
OAc
N
N N
N
Cl
NH2
T2691
O
OAc
AcO
OAc
N
N N
N
Cl
I
T2692
O
OAc
AcO
OAc
N
N N
NH
O
NH2
V0111
HN
N N
N
H2N
O
OO
O
NH2CH3
CH3
HCl. xH2O.
V0098
O
OH
HONHO
N
N
N
NH2
H2O.
X0008
O
OH
NHO
OH
N
NH
NH
O
O
2H2O.
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical S
cience
6 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Nucleotides and their AnalogsNucleotides are formed from the condensation of nucleoside and a phosphate group. The nucleosides themselves are formed from a nucleobase (see below) and a sugar moiety which is either ribose (RNA) or 2'-deoxyribose (DNA). Nucleotides are the minimum structural units of DNA and RNA, and serve as important cofactors in metabolism.
Pyrimidine Nucleotides
Product No. Product Name Unit SizeC0523 Cytidine 5'-Diphosphate Trisodium Salt Hydrate 10mg 100mg 1gC1675 Cytidine 5'-Monophosphate 5gC0524 Cytidine 5'-Monophosphate Disodium Salt Hydrate 1g 5gC2632 Cytidine 5'-Triphosphate Disodium Salt Hydrate 200mg 1gD3673 2'-Deoxycytidine 5'-Monophosphate Hydrate 100mg 1gT0845 Thymidine 5'-Monophosphate Disodium Salt Hydrate 100mgU0086 Uridine 5'-Diphosphate Disodium Salt Hydrate 1g 5gU0021 Uridine 5'-Monophosphate Disodium Salt Hydrate 5g 25gU0022 Uridine 5'-Triphosphate Trisodium Salt Hydrate 100mg
C0523
O
OH
O N
N
NH2
O
OHxH2O.
P
O
O
ONa
P
O
ONa
NaO
C1675
O
OH
O N
N
NH2
O
OH
P
O
HO
OH
C0524
O
OH
O N
N
NH2
O
OH
xH2O.
P
O
NaO
ONa
C2632
O
OH
NO
N
O
NH2
OH
P
O
OH
OP
O
O
ONa
P
O
HO
ONa
xH2O.
D3673
O
OH
O N
N
NH2
OP
O
OH
HO
xH2O.
T0845
O
OH
NOPNaO
O
ONa
HN
O
O
CH3
xH2O.
U0086
xH2O.
O
OH
NO
HN
O
O
OH
P
O
O
ONa
P
O
ONa
HO
U0021
O
OH
NO
OH
PNaO
O
NaO
HN
O
O
xH2O.
U0022
xH2O
O
OH
NO
OH
PO
O
ONa
HN
O
O
POPHO
O
ONa
O
ONa.
Purine Nucleotides
Product No. Product Name Unit SizeA2381 Adenosine 3',5'-Cyclic Monophosphate Hydrate 1g 5gA2112 Adenosine 3',5'-Cyclic Monophosphate Sodium Salt Hydrate 100mg 1gA0626 Adenosine 5'-Diphosphate Disodium Salt Hydrate 100mg 1gA0157 Adenosine 5'-Triphosphate Disodium Salt Hydrate 1g 25gA0159 Adenylic Acid Hydrate (2'- and 3'- mixture) from Yeast Price on requestA0158 5'-Adenylic Acid 1g 5g 25gF0913 Fludarabine Monophosphate 25mg 100mgG0338 Guanosine 5'-Monophosphate Hydrate 200mgG0172 Guanosine 5'-Monophosphate Disodium Salt Hydrate 25g 100gG0173 Guanylic Acid Sodium Salt (2'-,3'- mixture) from Yeast 1g 5gI0039 Inosine 5'-Monophosphate Barium Salt Hydrate 100mgI0036 Inosine 5'-Monophosphate Disodium Salt Hydrate 1g 5g 25gI0038 Inosine 5'-Triphosphate Trisodium Salt Hydrate 100mg
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical Science
7This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
A2381
O
O
O
OH
N
N
N
N
NH2
PO
OHxH2O.
A2112
O
O
O
OH
N
N N
N
NH2
xH2O
PO
ONa
.
A0626
O
OH
O
OH
N
N
P
O
ONa
OP
O
ONa
HO
xH2O.
N
N
NH2
A0157
O
OH
O
OH
N
N
xH2O
P
O
OH
OP
O
OH
OP
O
ONa
NaO
N
N
NH2
.
A0159
O
O
HO
O
N
N N
N
NH2
xH2O
P O
OH
HOH,
.
A0158
O
OH
O
OH
N
N N
N
NH2
P
O
OH
HO
F0913
O
OH
O
N
N N
N
NH2
P
O
OH
HO HO F
G0338
O
OH
O
OH
P
O
OH
HO
N
N N
NH
O
NH2
xH2O.
G0172
O
OH
NO
OH
P
N
NaO
O
NaO
N
NH
NH2
O
xH2O.
G0173
O
O
NHO
O
N
N
NH
NH2
O
P OHO
OH
H,
xNa.
I0039
xH2OO
OH
NO
OH
N
N
NH
O
PO
O
O .Ba2+
I0036
xH2OO
OH
NO
OH
N
N
NH
O
PNaO
O
NaO .
I0038
O
OH
NO
OH
PO
O
ONa
NHN
N
O
xH2O
PO
O
ONa
PHO
O
ONa.
Nucleic Acids
Product No. Product Name Unit SizeD0054 Deoxyribonucleic Acid not highly polymerized from Herring sperm 25gD3545 Deoxyribonucleic Acid Sodium Salt from Salmon Milt 5g 25gR0022 Ribonucleic Acid from Yeast 25gR0024 Ribonucleic Acid Sodium Salt from Yeast 25g
Enzymes and Coenzymes in Nucleic Acids
Product No. Product Name Unit SizeD1140 Deoxyribonuclease from Bovine Spleen 100mgD0919 -NAD Hydrate, oxidized form 1g 5gD0920 -NADH Disodium Salt Hydrate, reduced form 100mg 1g 5gT0521 -NADPH Tetrasodium Salt reduced form 100mgC0379 -NADP Sodium Salt Hydrate, oxidized form 100mg 1gN0943 -Nicotinamide Adenine Dinucleotide Phosphate 100mgP0251 Phosphatase, Acid from Wheat Germ 100mgT2979 Thionicotinamide Adenine Dinucleotide oxidized form 100mg
Nucleobases and their AnalogsNucleobases, usually simply called bases, are a vital sense component of DNA and RNA. The bases can be divided into two groups based on the structure: purines such as adenine and guanine; and pyrimidines such as cytosine, thymine and uracil. Other nucleobases can be created by the modifi cation of these basic structures. For example, hypoxanthine and xanthine are generated in living systems through deamination of adenine and guanine, respectively. Furthermore, nucleobase analogue 5-fl uorouracil (5-FU) is used as an anticancer agent. Derivatives of 2-fl uoroadenine have been widely reported as prodrug forms of anticancer agents.
Pyrimidine Nucleobases
Product No. Product Name Unit SizeA2089 N 4-Acetylcytosine 5g 25gA1918 2-Amino-5-chloropyrimidine 5gA2136 4-Amino-6-chloropyrimidine 1g 5gA2125 4-Amino-5-fl uoro-2-methoxypyrimidine 5g
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical S
cience
8 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Product No. Product Name Unit SizeA2449 6-Amino-1-methyluracil 5g 25gA0947 5-Aminoorotic Acid 25gA0558 6-Azauracil 1g 5gB3169 N 4-Benzoylcytosine 5gB0665 5-Bromouracil 25gC2300 6-Chloro-3-methyluracil 5g 25gC0969 5-Chlorouracil 5g 25gC2093 6-Chlorouracil 5g 25gC0528 Cytosine 5g 25g 100gD1619 1,3-Dimethyl-6-chlorouracil 5g 25gE0807 5-Ethyluracil 1g 5gF0321 5-Fluorocytosine 1g 5g 25gF0382 5-Fluoroorotic Acid Monohydrate 100mg 1gF0151 5-Fluorouracil 5g 25gI0531 5-Iodo-2,4-dimethoxypyrimidine 1g 5gI0219 5-Iodouracil 5g 25gI0814 Isocytosine 5gM0204 5-Methylcytosine Hydrochloride 100mg 1g 5gM2355 2-Methylthio-4-pyrimidinol 1g 5gM0994 5-Methyl-2-thiouracil 10g 25gO0065 Orotic Acid Monohydrate 25g 500gP0236 6-Phenyl-2-thiouracil 1g 5gT2757 4-Thiouracil 1gT0234 Thymine 5g 25g 100gT1622 5-(Trifl uoromethyl)uracil 1g 5gU0013 Uracil 25g 500g
A2089
NH
N
O
NH C
O
CH3
A1918
N
N
NH2
Cl
A2136
N
N
NH2
Cl
A2125
N
N
OCH3
F
NH2
A2449
N
NH
H2N
CH3
O
O
A0947
NH
NH
C
H2N
OO
O
OH
A0558
HN
NHN
OO
B3169
NH
N
O
NH C
O
B0665
NH
NH
O
O
Br
C2300
NH
N
O
O
CH3
Cl
C0969
NH
NH
O
O
Cl
C2093
NH
NH
O
OCl
C0528
N
NH
NH2
O
D1619
N
N
O
O
CH3
CH3
Cl
E0807
NH
NH
O
CH3CH2
O
F0321
N
NH
NH2
O
F
F0382
NH
NH
O
O
F
C
O
HO
H2O.
F0151
NH
NH
O
O
F
I0531
N
N
OCH3
OCH3
I
I0219
NH
NH
O
O
I
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical Science
9This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
I0814
NH
N
O
NH2
M0204
N
NH
CH3
O
NH2
. HCl
M2355
N
N
OH
SCH3
M0994
NH
NH
CH3
O
S
O0065
NH
NH
O
O
C
O
HOH2O.
P0236
NH
NH
O
S
T2757
NH
NH
O
S
T0234
NH
NH
O
O
CH3
T1622
NH
NH
O
O
CF3
U0013
NH
NH
O
O
Purine Nucleobases
Product No. Product Name Unit SizeA1248 2-Acetamido-6-hydroxypurine 1g 5gA0149 Adenine 25g 250gA0150 Adenine Hydrochloride Hemihydrate 25gA0151 Adenine Sulfate Dihydrate 25gA0907 Allopurinol 25g 250gA1407 2-Amino-6-chloropurine 1g 5gA2068 2-Amino-6-iodopurine 5g 25gA2805 Aminophylline 25g 100gA1111 2-Aminopurine 200mg 1gA1041 4-Aminopyrazolo[3,4-d]pyrimidine 100mgA0625 8-Azaguanine 1gA0555 8-Azahypoxanthine 1gA2069 Azathioprine 5g 25gB3344 N 6-Benzoyladenine 5g 25gB1088 N 6-Benzyladenine 5g 25gB3355 6-Benzyloxypurine 5g 25gB3456 8-Bromotheophylline 1g 5gC2042 Caffeine 25g 500gC2575 2-Chloroadenine 1g 5gC2306 6-Chloro-7-deazapurine 1g 5gC2748 7-(2-Chloroethyl)theophylline 5g 25gC2221 6-Chloro-2-fl uoropurine 1gC0278 6-Chloropurine 5g 25gC2470 4-Chloro-1H-pyrrolo[2,3-b]pyridine 200mg 1gC2845 6-Chloro-9-(tetrahydropyran-2-yl)purine 200mg 1gC0293 8-Chlorotheophylline 25g 250gD3604 N 2,9-Diacetylguanine 25gD1625 2,6-Diaminopurine Hydrate 5g 25gD4295 5,6-Dichlorobenzimidazole Hydrochloride 1g 5gD4284 2,6-Dichloro-7-deazapurine 1g 5gD2470 2,6-Dichloropurine 1g 5g 25gD3894 6-(Dimethylamino)purine 1g 5gD3600 Diprophylline 25g 500gD4302 Doxofylline 1g 25gH0402 Etofylline 25g 500gF0647 2-Fluoroadenine 200mg 1gG0169 Guanine 1g 25g 250gG0170 Guanine Hydrochloride Hydrate 25gG0168 Guanine Sulfate Dihydrate 1g 25gH1290 9-(2-Hydroxyethyl)adenine 5g 25gH0311 Hypoxanthine 25gI0370 Isoguanine 100mgK0009 Kinetin 1g 5gM0063 6-Mercaptopurine Monohydrate 1g 5gM1925 6-Methoxypurine 1g 5gM2432 1-Methylxanthine 50mg 200mg
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical S
cience
10 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Product No. Product Name Unit SizeM2073 3-Methylxanthine 5g 25gH1430 Proxyphylline 5g 25gT0179 Theophylline 25g 100g 500gT2941 Theophylline-7-acetic Acid 25gT0212 6-Thioguanine 1g 5gT0225 2-Thioxanthine 1g 5gX0004 Xanthine 25gX0007 Xanthopterin Hydrate 1g 5g
A1248
HN
N NH
N
O
NHC
O
CH3
A0149
N
N NH
N
NH2
A0150
N
N NH
N
NH2
HCl. 1/2 H2O.
A0151
N
N NH
N
NH2
H2SO4.
2H2O.2
A0907
N
N NH
N
OH
A1407
N
N NH
N
H2N
Cl
A2068
N
N NH
N
H2N
I
A2805
N
N NH
NCH3
CH3
O
O
H2NNH2
2
A1111
N
N NH
N
H2N
A1041
N
N
NH2
NH
N
A0625
HN
N NH
N
N
H2N
O
A0555
HN
N NH
N
N
O
A2069
N
N NH
N
S
N
N
O2N
CH3
B3344
N
N NH
N
NH C
O
B1088
N
N NH
N
CH2NH
B3355
N
N NH
N
OCH2
B3456
N
N NH
N
Br
O
O
CH3
CH3
C2042
N
N N
N
O
O
CH3
CH3
CH3
C2575
N
N NH
N
NH2
Cl
C2306
N
N
Cl
NH
C2748
N
N
N
CH2CH2Cl
O
NCH3
O
CH3
C2221
N
N NH
N
Cl
F
C0278
N
N NH
N
Cl
C2470
N NH
Cl
C2845
N
N N
N
Cl
O
C0293
N
N NH
N
O
O Cl
CH3
CH3
D3604
HN
N N
N
O
C
O
CH3
CH3 C
O
NH
D1625
N
N NH
N
H2N
NH2
. xH2O
D4295
NH
NCl
ClHCl.
D4284
NH
N
N
Cl
Cl
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical Science
11This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
D2470
N
N NH
N
Cl
Cl
D3894
N
N NH
N
NCH3
CH3
D3600
N
N N
N
CH3
O
CH3
O
CH2 CH
OH
CH2OH
D4302
N
N N
N
O
O
CH3
CH3
O
O
H0402
ON
NN
N
CH3
CH3
CH2CH2OHO
F0647
N
N NH
N
NH2
F
G0169
HN
N NH
N
O
H2N
G0170
N
HN
NH
N
O
H2N
HCl. xH2O.
G0168
N
HN
NH
N
O
H2N
2
H2SO4.
2H2O.
H1290
N
N N
N
CH2CH2OH
NH2
H0311
HN
N NH
N
O
I0370
N
NH
NH
N
O
NH2
K0009
OCH2NH
N
N NH
N
M0063
N
N NH
N
SH
. H2O
M1925
N
N NH
N
OCH3
M2432
NH
N
O
NH
NCH3
O
M2073
HN
N NH
N
O
O
CH3
H1430
N
N
CH3
O
CH3
N
N
O
CH2 CH CH3
OH
T0179
N
N NH
NCH3
CH3
O
O
T2941
N
N N
N
CH3
O
CH3
O
CH2 C
O
OH
T0212
HN
N NH
N
H2N
S
T0225
HN
NH
NH
N
O
S
X0004
HN
NH
NH
N
O
O
X0007
N
N N
N
OH
HO
NH2
xH2O.
Riboses and 2'-DeoxyribosesD- and L-Riboses and 2'-deoxyriboses, and their protected derivatives are shown below.
Product No. Product Name Unit SizeD4207 2-Deoxy-2,2-difl uoro-D-erythro-pentonic Acid -Lactone 3,5-Dibenzoate 1g 5gD4594 2-Deoxy-2-fl uoro-1,3,5-tri-O-benzoyl--D-arabinofuranose 1g 5gD0059 2-Deoxy-D-ribose 5g 25gM1965 Methyl -D-Ribofuranoside 1g 5gR0067 -D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate 5g 25gR0080 -L-Ribofuranose 1-Acetate 2,3,5-Tribenzoate 1gR0025 D-(-)-Ribose 25g 250gR0068 L-Ribose 1g 5g 25gR0082 -D-Ribose 1,5-Bis(phosphate) Tetrasodium Salt 5mgR0083 -D-Ribose 1,5-Bis(phosphate) Tetrasodium Salt Price on requestR0026 Ribose-5-phosphate Barium Salt Hydrate 100mg 1gR0066 Tetra-O-acetyl--D-ribofuranose 5g 25gT2607 1,2,3-Tri-O-acetyl-5-deoxy--D-ribofuranose 5g 25gT2641 1,3,5-Tri-O-benzoyl--D-ribofuranose 5g 25g
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical S
cience
12 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
D4207
O
OBz
BzO
F
F
O
D4594
O
OBzOBz
FBzO
D0059
CHO
H H
H OH
H OH
CH2OH
M1965
O
OH OH
OCH3HO
R0067
O
OBz
OAcBzO
OBz
R0080
O
OAc
OBz
BzO
OBz
R0025
O
OH
HO
OH
OH
R0068
OOHOH
OHHO
R0082
O
OOH
O
OH
P
O
ONa
NaO
P
O
ONa
ONa
R0083
O
OH
O
OH
P
O
ONa
NaO
O
ONa
ONaO P
R0026
xH2O
O
OH
O
OH
OH
PO
O
OBa 2
.
R0066
O
OAc
OAcAcO
OAc
T2607
O
OAc
OAcCH3
OAc
T2641
O
OBz
BzO
OHOBz
Nucleic Acid Synthesis AgentsSilylation converts insoluble nucleobases into lipophilic trimethylsilyled derivatives, which are readily soluble in organic solvents, permitting homogenous chemical reactions. The trimethylsilylated nucleobases react with protected sugars to aff ord nucleosides. The procedure is commonly referred to as the Hilbert-Johnson reaction modifi ed by Vorbrggen et al.Phosphorylating and phosphorothioating agents, condensing agents and protecting agents for hydroxy and amino groups are of importance in the synthesis of DNA and RNA chains. Active research on chemical synthesis of DNA and RNA is being conducted, and a variety of synthetic methods using these agents are being developed. The dicyclohexylcarbodiimide (DCC) method exemplified by the Khorana group, the phosphotriester method and phosphitetriester method by the team of Letsinger and the phosphoramidite method by the Caruthers group are examples of the various synthetic methods. Recently, the phosphoramidite method has been used frequently in tandem with the penetration of DNA synthesizers, thus 2-cyanoethyl N,N,N',N'-tetraisopropylphosphordiamidite has been the reagent of frequent choice for the phosphitylation due to its ease in handling and safety.3) 1,2,4-Triazole and 1H-tetrazole are also used for chemical conversion of uridines into cytidines.Chemically synthesized DNA is becoming important as a primer for the PCR method, an antisense molecule, or an element of the DNA computer.
Protecting Agents for Hydroxyl and Amino Groups
Product No. Product Name Unit SizeA0082 Acetyl Chloride 100g 500gB1151 1,3-Benzodithiolylium Tetrafl uoroborate 5gB0078 Benzoic Anhydride 25g 100g 500gB0105 Benzoyl Chloride 25mL 500mLB0511 BSA 10mL 100mLB1223 tert-Butyldiphenylchlorosilane 5mL 25mL 100mLC0832 4-Chlorophenoxyacetyl Chloride 25g 500gC0306 Chlorotrimethylsilane 25mL 100mL 500mLD2504 2-Chlorotrityl Chloride 25gD2469 Di-tert-butyldichlorosilane 5gD3135 Di-tert-butylsilyl Bis(trifl uoromethanesulfonate) 1g 5gD1608 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane 5g 25gD2334 1,3-Dichloro-1,1,3,3-tetramethyldisiloxane 5g 25gD1612 4,4'-Dimethoxytrityl Chloride 5g 25gD1293 N,N-Dimethylformamide Dimethyl Acetal 25mL 100mL 500mLH0089 HMDS 25mL 100mL 500mL
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical Science
13This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
Product No. Product Name Unit SizeI0115 Isobutyryl Chloride 25g 100g 500gM0721 4-Methoxybenzoyl Chloride 25g 100g 500gM0790 4-Methoxytrityl Chloride 25g 250gN0404 2-Nitrobenzyl Bromide 5g 25gP0113 Phenoxyacetyl Chloride 25g 500gP0677 Pivaloyl Chloride 25mL 500mLB0995 TBSCl 5g 25g 100gT0459 2,4,6-Triisopropylbenzenesulfonyl Chloride 25g 500gT0871 Trimethylsilyl Trifl uoromethanesulfonate 5g 25g 250gT1071 4,4',4''-Tris(benzoyloxy)trityl Bromide 5g 25gT1526 4,4',4''-Tris(4,5-dichlorophthalimido)trityl Bromide 1gT0512 Trityl Bromide 25g 100gC0308 Trityl Chloride 25g 100g 500g
A0082
CH3 Cl
O
B1151
S
SBF4
B0078
C
O
O C
O
B0105
C
O
Cl
B0511
CH3 C O
N
Si
Si CH3
CH3
CH3CH3
CH3
CH3
B1223
C Si Cl
H3C
H3C
H3C
C0832
O CH2 C
O
ClCl
C0306
Si
CH3
CH3 Cl
CH3
D2504
C Cl
Cl
D2469
Cl
Si
Cl
CC CH3
CH3
CH3
H3C
H3C
H3C
D3135
O Si
C(CH3)3
C(CH3)3
S
O
O
CF3 O S
O
O
CF3
D1608
Si O SiCl Cl
CH(CH3)2
CH(CH3)2
(CH3)2HC
(CH3)2HC
D2334
Si O SiCl Cl
CH3
CH3
CH3
CH3
D1612
CCH3O
OCH3
Cl
D1293
NOCH3
OCH3
CH3
CH3
H0089
Si NH Si
CH3
CH3
CH3
CH3
CH3
CH3
I0115
CH3Cl
O
CH3
M0721
C
O
Cl
OCH3
M0790
C ClCH3O
N0404
NO2
CH2Br
P0113
O
ClO
P0677
(CH3)3C C
O
Cl
B0995
Si
CH3
ClC
CH3
CH3
CH3
CH3
T0459
SO2Cl
CH
CH
CH3
CH3
CH3
CH3
CH3CH
CH3
T0871
O Si
CH3
CH3
CH3S
O
O
CF3
T1071
OC
O
CBr
3
T1526
N
O
OCl
Cl
CBr
3
T0512
C Br
C0308
C Cl
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical S
cience
14 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Phosphorylating and Phosphorothioating Agents
Product No. Product Name Unit SizeC0978 Barium 2-Cyanoethylphosphate Hydrate 5g 25gB3125 3H-1,2-Benzodithiol-3-one 1,1-Dioxide 1g 5gB4075 Bis(2-cyanoethyl) N,N-Diisopropylphosphoramidite 1g 5gB3623 Bis(phenylacetyl) Disulfi de 5g 25gC1210 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one 5g 25gC1215 2-Chloro-1,3,2-dioxaphospholane 25gC1250 2-Chloro-2-oxo-1,3,2-dioxaphospholane 5g 25gC0976 2-Chlorophenyl Phosphorodichloridate 5g 25gC0977 4-Chlorophenyl Phosphorodichloridate 5g 25gC2228 2-Cyanoethyl N,N,N ',N '-Tetraisopropylphosphordiamidite 1g 5gD2624 Dibenzyl N,N-Diisopropylphosphoramidite 5gD4252 Di-tert-butyl N,N-Diethylphosphoramidite 1gD4211 Di-tert-butyl N,N-Diisopropylphosphoramidite 1g 5gD0624 Diethyl Chlorothiophosphate 25g 500gD0764 Dimethyl Chlorothiophosphate 25gD1059 Diphenyl Chlorophosphate 25g 100g 500gD2883 Diphosphoryl Chloride 25gM0905 Methyl Dichlorophosphite 10gM0904 Methyl Phosphorodichloridate 5g 25g 100gP0209 Phenyl Dichlorophosphate 25g 500gP1223 Tetrabenzyl Pyrophosphate 1g
C0978
Ba2+
xH2O.
P
O
NCCH2CH2O
O
O
B3125
SS
O O
O
B4075
OCH2CH2CN
PN OCH2CH2CN
(CH3)2CH
(CH3)2CH
B3623
SS
O
O
C1210
OP
O
O
Cl
C1215
POO
Cl
C1250
P
O
O
O
Cl
C0976
O P
OCl
ClCl
C0977
O P
OCl
Cl
Cl
C2228
OCH2CH2CN
PN N
CH(CH3)2
CH(CH3)2
(CH3)2CH
(CH3)2CH
D2624
P NBnO
BnO CH(CH3)2
CH(CH3)2
D4252
P
N
(CH3)3CO OC(CH3)3
CH3CH3
D4211
(CH3)3COP
OC(CH3)3
N CH3CH3
CH3 CH3
D0624
P
S
OCH2CH3
OCH2CH3
Cl
D0764
P
S
CH3O Cl
OCH3
D1059
O P
O
O
Cl
D2883
Cl P
Cl
O
O P
O
Cl
Cl
M0905
CH3O PCl
Cl
M0904
P
O
CH3OCl
Cl
P0209
O P
OCl
Cl
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical Science
15This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
P1223
22
P
O
CH2O O P
O
OCH2
Condensing Agents
Product No. Product Name Unit SizeB3020 5-(Benzylthio)-1H-tetrazole 25gC2325 1,1'-Carbonyldi(1,2,4-triazole) 5g 25gC2421 1-(Cyanomethyl)piperidinium Tetrafl uoroborate 5gD2026 4,5-Dicyanoimidazole 25g 250gD0436 N,N '-Dicyclohexylcarbodiimide 25g 400gD3792 N,N '-Dicyclohexyl-4-morpholinecarboxamidine 25gE0670 5-(Ethylthio)-1H-tetrazole 1g 5gM1186 2,4-Mesitylenedisulfonyl Dichloride 5g 25gM0071 2-Mesitylenesulfonyl Chloride 25g 500gM0625 1-(2-Mesitylenesulfonyl)imidazole 1gN0477 3-Nitro-1,2,4-triazole 5gP0677 Pivaloyl Chloride 25mL 500mLT1562 2,4,5,6-Tetramethylbenzenedisulfonyl Dichloride 5gT1017 1H-Tetrazole 5g 25gT1985 1-(p-Toluenesulfonyl)imidazole 5g 25gT0340 1,2,4-Triazole 25g 100g 500gT0459 2,4,6-Triisopropylbenzenesulfonyl Chloride 25g 500gT1410 1-(2,4,6-Triisopropylbenzenesulfonyl)imidazole 5g 25gT2951 1-(2,4,6-Triisopropylbenzenesulfonyl)-1,2,4-triazole 1g 5g
B3020
N
NH
N
N
CH2S
C2325
NN
N N
NC
O
N
C2421
N
BF4
H CH2CN
D2026
NH
NNC
NC
D0436
N C N
D3792
C
N
O
N NH
E0670
N
NH
N
N
CH3CH2S
M1186
SO2Cl
SO2Cl
CH3
CH3CH3
M0071
SO2Cl
CH3
CH3
CH3
M0625
N
N
SO2 CH3
CH3
CH3
N0477
NH
N
NNO2
P0677
(CH3)3C C
O
Cl
T1562
SO2Cl
CH3
CH3
CH3
CH3
SO2Cl
T1017
N
NH
N
N
T1985
N
N
SO2 CH3
T0340
N
NH
N
T0459
SO2Cl
CH
CH
CH3
CH3
CH3
CH3
CH3CH
CH3
T1410
SO2
N
N
CH(CH3)2
CH(CH3)2
CH(CH3)2
T2951
SO2
N
NN
CHCH
CH
CH3CH3
CH3CH3
CH3
CH3
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical S
cience
16 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
References1) H. Vorbruggen, C. Ruh-Pohlenz, in Handbook of Nucleoside Synthesis, Wiley-Interscience, New York, 2001; H. Vorbruggen, C. Ruh-Pohlenz, in Organic Reactions, ed. by L. A. Paquette et al., John Wiley & Sons, 2000, Vol. 55; D. M. Huryn, M. Okabe, Chem. Rev. 1992, 92 , 1745; E. Ichikawa, K. Kato, Curr. Med. Chem. 2001, 8, 385.
2) Z. Liu, S. Liu, Z. Xie, W. Blum, D. Perrotti, P. Paschka, R. Klisovic, J. Byrd, K. K. Chan, G. Marcucci, Nucleic Acids Res. 2007, 35, e31; A. A. Magaa, K. Wrobel, Y. A. Caudillo, S. Zaina, G. Lund, K. Wrobel, Anal. Biochem. 2008, 374, 378; M. Munzel, D. Globisch, T. Bruckl, M. Wagner, V. Welzmiller, S. Michalakis, M. Mller, M. Biel, T. Carell, Angew. Chem. Int. Ed. 2010, 49, 5375.
3) I. Okamoto, K. Shohda, K. Seio, M. Sekine, J. Org. Chem. 2003, 68, 9971; A. Misra, S. Mishra, K. Misra, Bioconjugate Chem. 2004, 15, 638.; R. Gukathasan, M. Massoudipour, I. Gupta, A. Chowdhury, S. Pulst, S. Ratnam, Y. S. Sanghvi, S. A. Laneman, J. Organomet. Chem. 2005, 690, 2603.
Nucleosides, Nucleotides, Nucleic AcidsBioscience
Analytical Science
17This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
Amino Acids
Amino acids are molecules which contain both amino and carboxyl groups. In a generic sense the term refers to -amino acids which are the constituents of proteins. The stereochemistry of amino acids is defi ned by D and L enantiomers. The 20 proteinogenic amino acids are L-isomers, and their enantiomeric D-isomers are rarely found in nature. The estimated 100,000 or more diff erent proteins in life consist from the twenty diff erent L--amino acids connected by peptide bonds between the carbonyl and amino groups of amino acid residues. Although the so-called 20 proteinogenic amino acids are found in all forms of life, D-amino acids and peptides containing them have been discovered to play an important part in a range of biochemical systems.Amino acids and their N-protected derivatives, e.g. Boc and Fmoc amino acids, have vital roles in
technology since they are utilized to synthesize various bioactive substances from other molecules, for example peptide sweeteners, nutritional supplements, cosmetic materials, surfactants, and synthetic precursors of pharmaceuticals like insulin. Typical amino acids, their protected and biologically-modifi ed reagents, and non-proteinogenic amino acids are shown as follows.
We use the following abbreviations of the N-protective groups for the structures which appear in this section.
Boc(t-Butoxycarbonyl)
(CH3)3CO
O
Cbz, Z(Carbobenzoxy)
O
O
Fmoc(9-Fluorenylmethoxycarbonyl)
O
O
Bzl(Benzyl)
Bz(Benzoyl)
O
CH3
O
Ac(Acetyl)
-Amino Acids
Product No. Product Name Unit SizeC0518 Cystine (DL- and meso- mixture) 1g 5gA0178 H-DL-Ala-OH 25g 500gA0177 H-D-Ala-OH 5g 25gA0179 H-Ala-OH 25g 250gA1029 H-D-Arg-OH 1g 5gA0526 H-Arg-OH 25g 100g 500gA0527 H-DL-Arg-OHHCl 1g 5g 25gA0528 H-Arg-OHHCl 25g 500gA0541 H-DL-Asn-OH Monohydrate 25g 500gA0543 H-D-Asn-OH Monohydrate 25gA0542 H-Asn-OH Monohydrate 25g 250gA0544 H-DL-Asp-OH 25g 500gA0545 H-D-Asp-OH 25gA0546 H-Asp-OH 25g 500gC0515 H-Cys-OH 25g 100g 500gC0519 (H-Cys-OH)2 25g 500gC0520 (H-Cys-OH)22HCl 25gC0516 H-DL-Cys-OHHCl Monohydrate 25gC1329 H-D-Cys-OHHCl Monohydrate 5g 25gC0517 H-Cys-OHHCl Monohydrate 25g 500gG0062 H-DL-Gln-OH 1g 10gG0278 H-D-Gln-OH 1g 5gG0063 H-Gln-OH 25g 500gG0058 H-DL-Glu-OH 25g 500gG0057 H-D-Glu-OH 25g 250gG0059 H-Glu-OH 25g 500gG0060 H-Glu-OHHCl 25g 500gG0188 H-Glu-OH.Na Monohydrate 25g 500g
Amino AcidsBioscience
Analytical S
cience
18 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Product No. Product Name Unit SizeG0099 H-Gly-OH 25g 500gG0103 H-Gly-OHHCl 25g 500gG0424 H-Gly-OH.1/3H2SO4 5g 25gH0148 H-DL-His-OH 1g 25gH0998 H-D-His-OH 5g 25gH0149 H-His-OH 25g 250gH0150 H-His-OHHCl Monohydrate 25g 500gI0180 H-DL-Ile-OH (mixture of 4 stereoisomers) 5g 25gI0181 H-Ile-OH 25g 500gL0028 H-DL-Leu-OH 25gL0027 H-D-Leu-OH 5g 25gL0029 H-Leu-OH 25g 100g 500gL0129 H-Lys-OH 5g 25gL0070 H-DL-Lys-OHHCl 25g 100gL0128 H-D-Lys-OHHCl 5g 25gL0071 H-Lys-OHHCl 25g 500gL0130 H-DL-Lys-OH2HCl 25gL0131 H-Lys-OH2HCl 25gM0463 H-DL-Met-OH 25g 500gM0102 H-D-Met-OH 1g 5g 25gM0099 H-Met-OH 25g 100g 500gO0063 H-DL-Orn-OHHCl 1gO0064 H-Orn-OHHCl 25g 250gO0089 H-Orn-OH2HCl 1g 5gP0136 H-DL-Phe-OH 25g 250gP0135 H-D-Phe-OH 5g 25gP0134 H-Phe-OH 25g 250gP0480 H-DL-Pro-OH 1g 25gP0994 H-D-Pro-OH 5g 25gP0481 H-Pro-OH 25g 250gS0034 H-DL-Ser-OH 25g 500gS0033 H-D-Ser-OH 5g 25gS0035 H-Ser-OH 5g 25g 250gT0229 H-DL-Thr-OH 25gT0228 H-D-Thr-OH 25g 500gT0230 H-Thr-OH 25g 100g 500gT0540 H-DL-Trp-OH 25gT0539 H-D-Trp-OH 5g 25gT0541 H-Trp-OH 25gT0549 H-DL-Tyr-OH 5g 25gT1141 H-D-Tyr-OH 5g 25gT0550 H-Tyr-OH 25g 500gT1423 H-Tyr-OH.2Na Hydrate 25gV0013 H-DL-Val-OH 25g 500gV0012 H-D-Val-OH 1g 25gV0014 H-Val-OH 25g 100g 500gO0440 L-Ornithine L-Aspartate 25gS0900 L-Selenocystine Monohydrate 250mg
C0518
HO
O
NH2S
S
O
OH
NH2
A0178
OH
O
CH3
NH2
A0177
OH
O
CH3
NH2
A0179
OH
O
CH3
NH2
A1029
OH
O
NH2
NH
H2N
NH
A0526
OH
O
NH2
NH
H2N
NH
A0527
HCl.OH
O
NH2
NH
H2N
NH
A0528
OH
O
NH2
NH
NH
H2N
HCl.
A0541
H2O.OH
O
NH2
H2N
O
A0543
H2O.OH
O
NH2
H2N
O
Amino AcidsBioscience
Analytical Science
19This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
A0542
H2O.OH
O
NH2
H2N
O
A0544
OH
O
NH2
HO
O
A0545
OH
O
NH2
HO
O
A0546
OH
O
NH2
HO
O
C0515
OH
O
NH2
HS
C0519
HO
O
NH2S
SNH2
O
OH
C0520
OH
O
NH2
SS
NH2
O
HO 2HCl.
C0516
HCl. H2O.OH
O
NH2
HS
C1329
HCl. H2O.OH
O
NH2
HS
C0517
HCl. H2O.OH
O
NH2
HS
G0062
OH
O
NH2
H2N
O
G0278
OH
O
NH2
H2N
O
G0063
OH
O
NH2
H2N
O
G0058
OH
O
NH2
HO
O
G0057
OH
O
NH2
HO
O
G0059
OH
O
NH2
HO
O
G0060
HCl.OH
O
NH2
HO
O
G0188
ONa
OO
HONH2
H2O.
G0099
OH
OH2N
G0103
HCl.OH
OH2N
G0424
H2NOH
O
1/3H2SO4.
H0148
OH
O
NH2HN
N
H0998
OH
O
NH2HN
N
H0149
OH
O
NH2HN
N
H0150
HCl. H2O.OH
O
NH2HN
N
I0180
OH
O
NH2
CH3
CH3
I0181
OH
O
NH2
CH3
CH3
L0028
OH
O
NH2
CH3
CH3
L0027
OH
O
NH2
CH3
CH3
L0029
OH
O
NH2
CH3
CH3
L0129
OH
O
NH2
H2N
L0070
HCl.OH
O
NH2
H2N
L0128
HCl.OH
O
NH2
H2N
L0071
HCl.OH
O
NH2
H2N
L0130
2HCl.OH
O
NH2
H2N
L0131
2HCl.OH
O
NH2
H2N
M0463
OH
O
NH2
CH3S
M0102
OH
O
NH2
CH3S
M0099
OH
O
NH2
CH3S
O0063
HCl.OH
O
NH2
H2N
Amino AcidsBioscience
Analytical S
cience
20 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
O0064
HCl.OH
O
NH2
H2N
O0089
2HCl.OH
O
NH2
H2N
P0136
OH
O
NH2
P0135
OH
O
NH2
P0134
OH
O
NH2
P0480
NH
OH
O
P0994
NH
OH
O
P0481
NH
OH
O
S0034
OH
O
NH2
HO
S0033
OH
O
NH2
HO
S0035
OH
O
NH2
HO
T0229
OH
O
NH2
CH3
OH
relative
T0228
OH
O
NH2
CH3
OH
T0230
OH
O
NH2
CH3
OH
T0540
NH
NH2
OH
O
T0539
NH
NH2
OH
O
T0541
NH
NH2
OH
O
T0549
OH
O
NH2HO
T1141
OH
O
NH2HO
T0550
OH
O
NH2HO
T1423
xH2O.ONa
O
NH2NaO
V0013
OH
O
NH2
CH3
CH3
V0012
OH
O
NH2
CH3
CH3
V0014
OH
O
NH2
CH3
CH3
O0440
NH2O
HO
O
OH
NH2
H2N
O
OH
.
S0900
HO SeSe OH
O
O
NH2
NH2H2O.
Biologically-modifi ed Amino Acids
Product No. Product Name Unit SizeD0612 3,5-Diiodo-L-tyrosine Dihydrate 25gD0728 N,N-Dimethylglycine Hydrochloride 25gD0599 DL-DOPA 1gG0167 Glycocyamine 25g 500gM1365 H-Arg(Me)-OH.AcOH 100mgH1169 H-cis-Hyp-OH 100mg 1gH1358 H-D-cis-Hyp-OH 1g 5gH0296 H-Hyp-OH 5g 25gA2213 H-Lys(Ac)-OHHCl 1gM0101 H-DL-Met(O)-OH 5g
Amino AcidsBioscience
Analytical Science
21This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
Product No. Product Name Unit SizeG0061 H-DL-Pyr-OH 25g 500gP1354 H-D-Pyr-OH 5g 25gP0573 H-Pyr-OH 25g 500gM0452 H-DL-Trp(5-Me)-OH 100mg 1gH0531 H-Trp(5-OH)-OH 1g 5gI0075 H-Tyr(3-I)-OH 1g 5gD0600 Levodopa 5g 25gM0777 Me-DL-Ala-OH 100mgM1360 Me-D-Asp-OH 100mgM0778 Me-DL-Glu-OH 100mgS0841 Me-Gly-OEtHCl 5g 25gM0332 Me-Gly-OH 25g 100g 500gM0256 Me-Gly-ONa (ca. 40% in Water) 25mL 500mLM0100 DL-Methionine Sulfone 1g 5gP0772 DL-O-Phosphoserine Price on requestP0773 L-O-Phosphoserine 5g 25gP0255 O-Phospho-DL-threonine 1gP0959 O-Phospho-L-tyrosine 100mgS0462 DL-Selenomethionine 1gS0442 L-Selenomethionine 1g 5gT0219 L-Thioproline 25g 500gT0241 DL-Thyronine 100mgT0242 DL-Thyroxine Price on requestT0245 L-Thyroxine Sodium Salt Pentahydrate 100mg 1gT0453 3,3',5-Triiodo-L-thyronine 100mgM0644 S-Methylmethioninesulfonium Chloride 25g 500g
D0612
2H2O.
OH
O
NH2HO
I
I
D0728
HCl.CH3
NOH
OCH3
D0599
OH
O
NH2HO
HO
G0167
OH
OHN
NH
H2N
M1365
OH
O
NH2
NH
NH
NH
CH3
CH3COOH.
H1169
NH
OH
O
HO
H1358
NH
OH
O
HO
H0296
NH
HO
OH
O
A2213
HCl.
OH
O
NH2
HN
Ac
M0101
O
OH
O
NH2
SCH3
G0061
NH
OOH
O
P1354
NH
OOH
O
P0573
NH
OOH
O
M0452
NH
NH2
OH
O
CH3
H0531
NH
NH2
OH
O
HO
I0075
OH
O
NH2HO
I
D0600
OH
O
NH2HO
HO
M0777
OH
O
CH3
HNCH3
M1360
OH
O
HN
HO
OCH3
M0778
OH
O
HN
HO
O
CH3
Amino AcidsBioscience
Analytical S
cience
22 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
S0841
CH3
HN
O CH3
O
HCl.
M0332
OH
OHN
CH3
M0256
ONa
OHN
CH3
M0100
OH
O
NH2
CH3SO2
P0772
OH
O
NH2
OP
HO
OHO
P0773
OH
O
NH2
OP
HO
OHO
P0255
OH
O
CH3
OP
O
HO
HO
NH2relative
P0959
OH
O
NH2O
P
OHO
HO
S0462
OH
O
NH2
CH3Se
S0442
OH
O
NH2
CH3Se
T0219
NH
S
C
O
HO
T0241
OH
O
NH2O
HO
T0242
OH
O
NH2O
HO
I
I
I
I
T0245
5H2O.
ONa
O
NH2O
HO
I
I
I
I
T0453
OH
O
NH2O
I
I
HO
I
M0644
HO
O
S
CH3
NH2
ClCH3
non-Proteinorganic Amino Acids
Product No. Product Name Unit SizeA1443 2-Acetamidoacrylic Acid 5gA0212 D-Alloisoleucine 1gA2214 L-Alloisoleucine 200mg 1gA0214 DL-Allothreonine (contains Threonine) 100mg 1gA1518 D-Allothreonine 100mg 1gA1519 L-Allothreonine 100mg 1gA1468 S-Allyl-L-cysteine 5gA1647 D-2-Allylglycine Hydrochloride 200mg 1gA1648 L-2-Allylglycine Hydrochloride 200mg 1g 5gA2153 D-2-Aminoadipic Acid 1g 5gA1457 L-2-Aminoadipic Acid 1g 5gA1450 (S)-(+)-2-Amino-4-bromobutyric Acid Hydrobromide 1g 5gA0280 DL-2-Aminobutyric Acid 25gA1377 (R)-(-)-2-Aminobutyric Acid 1g 5gA0826 (S)-(+)-2-Aminobutyric Acid 1g 5gA2032 1-Aminocyclobutanecarboxylic Acid Hydrochloride 5gA1068 1-Aminocyclohexanecarboxylic Acid 25g 100gA1063 1-Aminocyclopentanecarboxylic Acid 1g 5g 25gA1178 1-Aminocyclopropanecarboxylic Acid 100mg 1gA0382 DL-2-Amino-n-octanoic Acid 1g 5g 25gA0404 DL-2-Aminopimelic Acid 1gA1279 DL-2-Aminosuberic Acid 5gA1367 2-Amino-4,4,4-trifl uorobutyric Acid Hydrochloride 100mg 1gA0497 Anthranilic Acid 25g 100g 500gA1043 L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline] 100mg 1gA1646 Azetidine-3-carboxylic Acid 100mgC0018 L-Canavanine Sulfate Hydrate 100mgC2781 S-(2-Carboxyethyl)-L-cysteine 100mg
Amino AcidsBioscience
Analytical Science
23This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
Product No. Product Name Unit SizeC0371 DL-Citrulline 1gC0372 L-Citrulline 25g 250gC2659 3-Cyclohexyl-D-alanine Hydrate 1g 5gC0514 L-Cysteic Acid 1g 25gD3825 3,4-Dehydro-L-proline 100mg 1gD1175 DL-2,4-Diaminobutyric Acid Dihydrochloride 1g 5g 25gD0083 (S)-(+)-2,4-Diaminobutyric Acid Dihydrochloride 1gD0112 2,6-Diaminopimelic Acid 1g 5gD0438 DL-2,3-Diaminopropionic Acid Hydrochloride 1g 5g 25gD1573 (R)-(-)-2,3-Diaminopropionic Acid Hydrochloride 100mg 1gD1377 (S)-(+)-2,3-Diaminopropionic Acid Hydrochloride 100mg 1gD0213 3,5-Dibromo-L-tyrosine 1g 5gD2539 D-(-)-2-(2,5-Dihydrophenyl)glycine 5g 25gD1119 3,5-Diiodo-L-thyronine 100mg 1g 5gM1388 N,2-Dimethylalanine Hydrate 1g 5gD2690 N,N-Dimethyl--alanine Hydrochloride 5g 25gD3379 3,5-Dinitro-L-tyrosine Sodium Salt 1gD2224 N,N-Dipropyl-L-alanine 1gD0961 Djenkolic Acid 1gE0038 DL-Ethionine 5g 25gE0039 L-Ethionine 100mgE0530 N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanine 5g 25gF0818 trans-4-Fluoro-L-proline 50mgF0120 N-Formyl-DL-ethionine 100mg 1gA0282 GABA 25g 100g 500gG0215 Glycine Zinc Salt Monohydrate 5g 25gC1612 H-Ala(3-Cl)-OHHCl 1g 5gA0180 H--Ala-OH 25g 500gN0660 H-Arg(NO2)-OH 5g 25gN0661 H-Arg(NO2)-OMeHCl 5g 25gC2673 H-D-Chg-OH 1gC2569 H-Chg-OH 1g 5gH1427 4,4,4,4',4',4'-Hexafl uoro-DL-valine 200mgM0229 H-DL-Glu(2-Me)-OH Hemihydrate 100mg 1gH1172 H-HomoArg-OHHCl 1g 5gM0101 H-DL-Met(O)-OH 5gH0158 DL-Homocysteic Acid 1g 5gH0159 DL-Homocysteine 1g 5gH0160 DL-Homocystine 25gH1329 DL-Homophenylalanine 1g 5gH0984 D-Homophenylalanine 100mg 1gH0985 L-Homophenylalanine 100mg 1gP0442 DL-Homoproline 25g 250gP1830 D-Homoproline 5g 25gP1404 L-Homoproline 1g 5gA0319 DL-Homoserine 1g 5gH1224 D-Homoserine 1g 5gH1030 L-Homoserine 1g 5gO0063 H-DL-Orn-OHHCl 1gO0064 H-Orn-OHHCl 25g 250gO0089 H-Orn-OH2HCl 1g 5gB4245 H-DL-Phe(4-Br)-OH 1g 5gC0253 H-DL-Phe(4-Cl)-OH 1g 25gC2016 H-D-Phe(4-Cl)-OHHCl 1gC1709 H-Phe(4-Cl)-OHHCl 1g 5gF0170 H-DL-Phe(2-F)-OH 1g 5gF0273 H-Phe(2-F)-OH 100mg 1gF0169 H-DL-Phe(3-F)-OH 1g 5gF0272 H-Phe(3-F)-OH 100mgF0106 H-DL-Phe(4-F)-OH 1gF0901 H-D-Phe(4-F)-OH 1g 5gF0274 H-Phe(4-F)-OH 100mgN0849 H-D-Phe(4-NO2)-OH Hydrate 1g 5gN0682 H-Phe(4-NO2)-OH Hydrate 1g 5gN0878 H-Phe(4-NO2)-OMeHCl 1g 5gC2579 H-DL-Phg(2-Cl)-OH 5g 25gC2431 H-Phg(2-Cl)-OH 1g 5gC1401 H-DL-Phg(4-Cl)-OH 1g 5g
Amino AcidsBioscience
Analytical S
cience
24 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Product No. Product Name Unit SizeF0863 H-D-Phg(4-F)-OH 1g 5gF0862 H-Phg(4-F)-OH 1g 5gP0326 H-DL-Phg-OH 25g 500gP0820 H-D-Phg-OH 25g 500gP1288 H-Phg-OH 25g 100gH0758 H-D-Phg(4-OH)-OH 25g 500gH1389 H-Phg(4-OH)-OH 5g 25gL0157 H-D-Tle-OH 1g 5gL0147 H-Tle-OH 1g 5g 25gF0201 H-Tyr(3-F)-OH 100mgN0905 H-Tyr(3-NO2)-OH 5g 25gI0256 Isonipecotic Acid 25g 100g 500gK0016 L-Kynurenine Hydrate 100mgL0010 Lanthionine (DL- and meso- mixture) 100mgA0323 2-Methylalanine 25g 100g 500gD1817 -Methyl-L-DOPA Sesquihydrate 5g 25gN0665 3-(2-Naphthyl)-D-alanine 1g 5gN0646 3-(2-Naphthyl)-L-alanine 1g 5gN0772 3-(1-Naphthyl)-D-alanine Hydrochloride 1g 5gN0773 3-(1-Naphthyl)-L-alanine Hydrochloride 1g 5gN0683 3-(2-Naphthyl)-L-alanine Hydrochloride 1g 5gN0420 Nipecotic Acid 25g 500gN0302 DL-Norleucine 25gN0327 D-Norleucine 1g 10gN0303 L-Norleucine 100mg 1g 5gN0304 DL-Norvaline 25gN0673 D-Norvaline 1g 5g 25gN0686 L-Norvaline 1g 5gO0440 L-Ornithine L-Aspartate 25gP0025 DL-Penicillamine 1gP0147 D-Penicillamine 5g 25gP1370 L-Penicillamine 1g 5gP2085 Pentafl uoro-L-phenylalanine 200mg 1gA2480 -Phenylalanine 5g 25gP0180 N-Phenylglycine 25g 500gP0179 N-Phenylglycine Potassium Salt 25g 500gT0954 L-Theanine 1g 5gT0787 DL-m-Tyrosine 1g 5g
A1443
CH3HN
OH
O CH2
O
A0212
CH3OH
O
NH2
CH3
A2214
OHCH3
CH3
NH2
O
A0214
CH3 OH
O
NH2
OH
A1518
OH
O
NH2
OH
CH3
A1519
OH
O
NH2
OH
CH3
A1468
OH
O
NH2
SCH2
A1647
HCl.OH
O
NH2
CH2
A1648
HCl.
CH2OH
O
NH2
A2153
HOOH
O
O
NH2
A1457
OH
O
NH2
HO
O
A1450
OH
OBr
NH2
HBr.
A0280
OH
O
CH3NH2
A1377
CH3 OH
O
NH2
A0826
CH3 OH
NH2
O
Amino AcidsBioscience
Analytical Science
25This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
A2032
C
NH2
O
OHHCl.
A1068
CH2N
O
OH
A1063
H2N C
O
OH
A1178
H2N C
O
OH
A0382
OH
O
CH3NH2
A0404
OH
OO
HO
NH2
A1279
HOOH
O
O
NH2
A1367
CF3 OH
O
NH2
HCl.
A0497
C
O
OH
NH2
A1043
NH
OH
O
A1646
NH
C
O
HO
C0018
H2SO4. xH2O.
OH
O
NH2
ONH
H2N
NH
C2781
HO S OH
O
NH2
O
C0371
OH
O
NH2
NH
H2N
O
C0372
OH
O
NH2
NH
H2N
O
C2659
OH
O
NH2 xH2O.
C0514
OH
O
NH2
HO3S
D3825
NH
OH
O
D1175
OH
OH2N
NH2
2HCl.
D0083
OH
OH2N
NH2 2HCl.
D0112
HO
O O
OH
NH2NH2
D0438
OH
O
H2N
NH2
HCl.
D1573
OH
O
H2N
NH2
HCl.
D1377
OH
O
H2N
NH2
HCl.
D0213
OH
O
NH2HO
Br
Br
D2539
OH
O
NH2
D1119
OH
O
NH2O
I
I
HO
M1388
NH C
CH3
CH3
C
O
OHCH3
xH2O.
D2690
OH
O
N
CH3
CH3 HCl.
D3379
ONa
O
NH2HO
NO2
O2N
D2224
N
CH3OH
O
CH3CH3
D0961
OH
O
NH2
S
O
HO
NH2
S
E0038
OH
OSCH3
NH2
E0039
OH
O
NH2
SCH3
E0530
ONH
OH
O
CH3
O
CH3
F0818
NH
OH
O
F
F0120
O
OH
HN
SCH3
H
O
A0282
H2NOH
O
G0215
H2O.Zn2+
2
O
OH2N
C1612
OH
NH2 HCl.
O
Cl
Amino AcidsBioscience
Analytical S
cience
26 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
A0180
OH
O
H2N
N0660
OH
O
NH2
NH
NH
NH
O2N
N0661
HCl.
OCH3
O
NH2
NH
NH
NH
O2N
C2673
OH
NH2
O
C2569
NH2
O
OH
H1427
OH
NH2
O
CF3
CF3
M0229
CCH2CH2
NH2
C
O
HO
1/2H2O.
C
H3C O
OH
H1172
H2NHN
NH NH2
OH
O
HCl.
M0101
O
OH
O
NH2
SCH3
H0158
O
OH
NH2
HO3S
H0159
O
OH
NH2
HS
H0160
O
OH
NH2
SS
NH2
HO
O
H1329
OH
O
NH2
H0984
OH
NH2
O
H0985
OH
O
NH2
P0442
NH
C
O
OH
P1830
NH
C
O
OH
P1404
NH
C OH
O
A0319
OH
OHO
NH2
H1224
OH
O
HO
NH2
H1030
OH
O
HO
NH2
O0063
HCl.OH
O
NH2
H2N
O0064
HCl.OH
O
NH2
H2N
O0089
2HCl.OH
O
NH2
H2N
B4245
OH
O
NH2Br
C0253
OH
O
NH2Cl
C2016
HCl.
OH
O
NH2Cl
C1709
. HClOH
O
NH2Cl
F0170
OH
O
NH2
F
F0273
OH
O
NH2
F
F0169
OH
O
NH2
F
F0272
OH
O
NH2
F
F0106
OH
O
NH2F
F0901
OH
O
NH2F
F0274
OH
O
NH2F
N0849
xH2O.OH
O
NH2O2N
N0682
xH2O.
OH
O
NH2O2N
N0878
OCH3
O
NH2O2N
HCl.
C2579
OH
O
NH2Cl
C2431
OH
O
NH2Cl
Amino AcidsBioscience
Analytical Science
27This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
C1401
OH
O
NH2
Cl
F0863
F
OH
O
NH2
F0862
F
OH
O
NH2
P0326
OH
NH2
O
P0820
OH
O
NH2
P1288
OH
O
NH2
H0758
OH
O
NH2
HO
H1389
HO
OH
O
NH2
L0157
CH3 OH
NH2
CH3 OCH3
L0147
OH
O
NH2
CH3
CH3
CH3
F0201
OH
O
NH2
F
HO
N0905
OH
O
NH2HO
O2N
I0256
NH
C
O
OH
K0016
xH2O.
OH
O
NH2ONH2
L0010
HO
O
NH2
S
O
OH
NH2
A0323
H2N C
H3C
CH3
C
O
OH
D1817
OH
O
CH3 NH2
HO
HO1 1/2H2O.
N0665
OH
O
NH2
N0646
OH
O
NH2
N0772
HCl.OH
O
NH2
N0773
HCl.OH
NH2
O
N0683
HCl.OH
O
NH2
N0420
NH
C
O
OH
N0302
OH
O
NH2
CH3
N0327
OH
O
NH2
CH3
N0303
OH
O
NH2
CH3
N0304
OH
O
NH2
CH3
N0673
OH
O
NH2
CH3
N0686
OH
O
CH3
NH2
O0440
NH2O
HO
O
OH
NH2
H2N
O
OH
.
P0025
OH
O
NH2
CH3
SHCH3
P0147
OH
O
NH2
CH3
SHCH3
P1370
OH
O
NH2
CH3
SHCH3
P2085
OH
O
NH2
F
FF
F
F
A2480
OH
NH2 O
P0180
O
OH
HN
P0179
O
OK
HN
T0954
OH
O
NH2
NH
O
CH3
T0787
OH
O
NH2
HO
Amino AcidsBioscience
Analytical S
cience
28 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
N-Protected Amino AcidsAc-Amino AcidsProduct No. Product Name Unit SizeA0072 Ac-DL-Ala-OH 10gA0730 Ac-DL-Cys(Bzl)-OH 1gA0740 Ac-D-Cys(Bzl)-OH 100mgA0905 Ac-Cys-OH 25g 250gP0607 Ac-DL-Cys(Ph)-OH 5gA0014 -Acetamidocinnamic Acid 25gA0853 N-Acetyl-DL-2-aminobutyric Acid 5g 25gA0078 N-Acetylanthranilic Acid 25gA0087 N-Acetyl-3,5-diiodo-L-tyrosine 100mgA0784 Ac-Gln-OH 25gA0693 Ac-Glu-OH 25g 250gA0094 Ac-Gly-OEt 1g 25gA0093 Ac-Gly-OH 25g 100g 500gA0698 Ac-DL-His-OH Monohydrate 1g 5gA0873 Ac-His-OH Monohydrate 1g 25gA2265 Ac-Hyp-OH (cis- and trans- mixture) 5g 25gA0097 Ac-DL-Leu-OH 5g 25gA0713 Ac-D-Leu-OH 1gA0098 Ac-Leu-OH 5g 25gA2171 Ac-Lys-OH 1g 5gA0100 Ac-DL-Met-OH 25g 500gA2056 Ac-Met-OH 25gA0750 Ac-DL-Nle-OH 1g 25gA0105 Ac-D-Phe-OH 1g 5gA1541 Ac-Phe-OH 5g 25gA0122 Ac-Trp-OEt 1gA0120 Ac-DL-Trp-OH 1g 25gA0119 Ac-D-Trp-OH 1g 5gA0121 Ac-Trp-OH 1g 25gA0118 Ac-Tyr-OEt Monohydrate 1g 5gA1409 Ac-Tyr-OH 25gA0125 Ac-DL-Val-OH 25gA0678 Ac-D-Val-OH 1gA2366 Ac-Val-OH 5g 25g
A0072
OH
O
CH3
HNAc
A0730
OH
O
HN
S
Ac
A0740
OH
O
HN
S
Ac
A0905
OH
O
HN
HS
Ac
P0607
OH
O
HN
S
Ac
A0014
OH
O
HNAc
A0853
CH3 OH
O
HN O
CH3
A0078
C
NH C
OH
CH3
O
O
A0087
OH
O
HNHO Ac
I
I
A0784
OH
O
HN
H2N
O
Ac
A0693
OH
O
HN
HO
O
Ac
A0094
O
OHN
O
CH3CH3
A0093
OH
OHN
O
CH3
A0698
H2O.OH
O
HNHN
NAc
A0873
OH
O
HNHN
NAc H2O
.
Amino AcidsBioscience
Analytical Science
29This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
A2265
N
Ac
HO
OH
O
A0097
OH
O
HN
CH3
CH3Ac
A0713
OH
O
HN
CH3
CH3Ac
A0098
OH
O
HN
CH3
CH3Ac
A2171
OH
O
HN
H2N
Ac
A0100
OH
O
HN
CH3S
Ac
A2056
OH
O
HN
CH3S
Ac
A0750
OH
O
HN
CH3
Ac
A0105
OH
O
HNAc
A1541
OH
O
HNAc
A0122
OCH2CH3
O
HNAcN
H
A0120
HN
OH
O
AcNH
A0119
NH
HN
OH
O
Ac
A0121
HN
OH
O
AcNH
A0118
H2O.OCH2CH3
O
HNHO Ac
A1409
OH
O
HNHO Ac
A0125
OH
O
HN
CH3
CH3
Ac
A0678
OH
O
HN
CH3
CH3
Ac
A2366
CH3
CH3 OH
O
HNAc
Boc-Amino AcidsProduct No. Product Name Unit SizeB4292 Boc-7-Ahp-OH 1g 5gB3323 Boc-Aib-OH 5g 25gB4044 Boc-Ala(3-I)-OMe 1g 5gB4282 Boc-DL-Ala-OH 5g 25gB2175 Boc-D-Ala-OH 5g 25gB1184 Boc-Ala-OH 5g 25gB2176 Boc--Ala-OH 5g 25gB2204 Boc-D-Arg-OHHCl Monohydrate 1g 5gB1626 Boc-Arg-OHHCl Monohydrate 5g 25gB1497 Boc-Arg-pNAHCl 100mgB3766 Boc-Arg(Tos)-OH 5gB2964 Boc-D-Asn-OH 5g 25gB1627 Boc-Asn-OH 10gB3915 Boc-Asn-ONp 5gB3789 Boc-Asn(Trt)-OH 5g 25gB3935 Boc-Asp(OtBu)-OH 1g 5gB1628 Boc-Asp(OBzl)-OH 5g 25gB2965 Boc-D-Asp-OH 5gB2270 Boc-Asp-OH 5gB3540 1-Boc-azetidine-3-carboxylic Acid 1g 5gB2293 Boc-(Boc-3-aminopropyl)Gly-OH 200mgB3839 Boc-Chg-OH 1g 5gB3831 N-Boc-cycloleucine 1g 5gA2553 Boc-Cys(Acm)-OH 5gB1666 Boc-Cys(Bzl)-OH 5gA2515 Boc-Dab-OH 1g 5gA2470 Boc-Dap-OH 1g 5gB4202 N-Boc-4,4-difl uoro-L-proline 200mg 1gB3178 N-Boc-cis-4-fl uoro-L-proline 200mg 1gB3177 N-Boc-trans-4-fl uoro-L-proline 200mg 1g
Amino AcidsBioscience
Analytical S
cience
30 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Product No. Product Name Unit SizeB4291 Boc-GABA-OH 5g 25gB1649 Boc-Gln-OH 10g 25gB1864 Boc-Glu-OBzl 5g 25gB1633 Boc-Glu(OBzl)-OH 5g 25gB2987 Boc-D-Glu-OH 5g 25gB2177 Boc-Glu-OH 25gB4156 Boc-Gly-OtBu 1g 5gB1185 Boc-Gly-OH 5g 25gB3975 Boc-Gly-OMe 5g 25gB1634 Boc-His-OH 5g 25gB2066 Boc-His(Tos)-OH 5g 25gB1635 Boc-Hyp-OH 5gB3987 Boc-cis-Hyp-OMe 1g 5gB3843 Boc-Hyp-OMe 1g 5gB1186 Boc-Ile-OH Hemihydrate 5g 25gB3007 Boc-D-Leu-OH Hydrate 5g 25gB1187 Boc-Leu-OH Monohydrate 5g 25gB2178 Boc-Lys(Boc)-OHDCHA 5g 25gB3083 Boc-D-Lys-OH 1g 5gB1669 Boc-Lys-OH 5gB1632 Boc-Lys(Z)-OH 5g 25gB3650 Boc-N-Me-D-Ala-OH 1g 5gB3651 Boc-N-Me-Ala-OH 5g 25gB2967 Boc-D-Met-OH 5g 25gB1636 Boc-Met-OH 10gB3433 Boc-Met-OSu 5gB3615 N-Boc-3-(1-naphthyl)-D-alanine 1g 5gB3616 N-Boc-3-(2-naphthyl)-D-alanine 1g 5gB3617 N-Boc-3-(2-naphthyl)-L-alanine 1g 5gB3376 1-Boc-nipecotic Acid 5g 25gB2253 Boc-Orn(Z)-OH 5g 25gB4141 N-Boc-4-oxo-L-proline 1g 5gB3945 Boc-D-Phe(4-Br)-OH 1g 5gB3613 Boc-D-Phe(4-Cl)-OH 1g 5gB3614 Boc-Phe(4-Cl)-OH 1g 5gB4367 Boc-Phe(3-F)-OH 1g 5gB3303 Boc-D-Phe(4-F)-OH 1g 5gB3304 Boc-Phe(4-F)-OH 1g 5gB3626 Boc-D-Phe(3,4-F)-OH 1g 5gB3627 Boc-Phe(3,4-F)-OH 1gA2130 Boc-D-Phe(4-NH2)-OH 1g 5gA2131 Boc-Phe(4-NH2)-OH 1g 5gB3668 Boc-D-Phe(4-NO2)-OH 1g 5gB2232 Boc-Phe(4-NO2)-OH 1g 5gB2989 Boc-D-Phe-OH 5g 25gB1332 Boc-Phe-OH 5g 25gB4259 Boc-Phe-OMe 5g 25gB3230 Boc-D-Phg-OH 1g 5gB3211 Boc-Phg-OH 5g 25gB4011 N-Boc-2-phosphonoglycine Trimethyl Ester 1g 5gB3644 Boc-DL-Pip-OH 5g 25gB3700 Boc-Pip-OH 1g 5gB2977 Boc-D-Pro-OH 5g 25gB1188 Boc-Pro-OH 5g 25gB3414 Boc-D-Pro-OSu 1g 5gB4007 Boc-propargyl-Gly-OH 1gB4293 Boc-3-(2-pyridyl)-Ala-OH 1g 5gB4324 Boc-3-(3-pyridyl)-Ala-OH 1g 5gE0940 Boc-D-Pyr-OEt 1g 5gB4083 Boc-Pyr-OH 5g 25gB1863 Boc-D-Ser(Bzl)-OH 1g 5gB1629 Boc-Ser(Bzl)-OH 5gB2205 Boc-Ser(Bzl)-OSu 1g 5gB2258 Boc-D-Ser-OH 1g 5gB1637 Boc-Ser-OH 5g 25gB2073 Boc-Ser-OMe 5g 25gB1630 Boc-Thr(Bzl)-OH 5gB2990 Boc-D-Thr-OH 5g
Amino AcidsBioscience
Analytical Science
31This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
Product No. Product Name Unit SizeB1638 Boc-Thr-OH 10gB3995 Boc-D-Tle-OH 1g 5gB3754 Boc-Tle-OH 5g 25gB2260 Boc-Trp(For)-OH 5gB2259 Boc-D-Trp-OH 1g 5gB1639 Boc-Trp-OH 25gB3435 Boc-Trp-OSu 5gB3485 Boc-Tyr(tBu)-OH 1g 5gB1631 Boc-Tyr(Bzl)-OH 5g 25gB2963 Boc-D-Tyr-OH 1g 5gB1640 Boc-Tyr-OH 10g 25gB2005 Boc-Tyr-OMe 5g 25gB2991 Boc-D-Val-OH 5g 25gB1333 Boc-Val-OH 5g 25gC2535 4-Cyclohexyl N-Boc-L-aspartate 5g 25gB2179 5-Cyclohexyl N-Boc-L-glutamate 5g
B4292
O C
O
NH(CH2)6 C
O
OHCCH3
CH3
CH3
B3323
CH3OH
O
HNBoc
CH3
B4044
I OCH3
O
HNBoc
B4282
OH
O
CH3
HNBoc
B2175
OH
O
CH3
HNBoc
B1184
OH
O
CH3
HNBoc
B2176
BocNH
OH
O
B2204
HCl H2O. .
OH
O
HN
NH
H2N
NH
Boc
B1626
OH
O
HN
NH
H2N
NH
HCl H2O. . Boc
B1497
HClNH
O
HNNH
H2N
NHNO2
Boc.
B3766
OH
O
HNNH
NH
Boc
NH
S
CH3
O O
B2964
OH
O
HN
H2N
OBoc
B1627
OH
O
HN
H2N
OBoc
B3915
O
O
HN
H2N
OBoc
NO2
B3789
OH
O
HN
HN
OBoc
Ph
PhPh
B3935
OH
O
HN
(CH3)3CO
OBoc
B1628
OH
O
HN
O
OBoc
B2965
OH
O
HN
HO
OBoc
B2270
OH
O
HN
HO
OBoc
B3540
NBoc
HO
O
B2293
OH
ON
BocHN
Boc
B3839
HN
OH
O
Boc
B3831
NH
OH
O
Boc
A2553
CH3 NH
S
O
OH
O
HNBoc
B1666
OH
O
HN
S
Boc
Amino AcidsBioscience
Analytical S
cience
32 The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
A2515
OH
HN
O
H2N
Boc
A2470
OH
O
HN
H2N
Boc
B4202
N
Boc
F
O
F
OH
B3178
N
Boc O
OH
F
B3177
N
Boc O
OH
F
B4291
O C
O
NH(CH2)3 C
O
OHCCH3
CH3
CH3
B1649
OH
O
HN
H2N
O
Boc
B1864
O
O
HN
HO
O
Boc
B1633
OH
O
HN
O
O
Boc
B2987
OH
O
HN
HO
O
Boc
B2177
OH
O
HN
HO
O
Boc
B4156
Boc
HN
OC(CH3)3
O
B1185
Boc
HN
OH
O
B3975
Boc
HN
OCH3
O
B1634
OH
O
HNHN
NBoc
B2066
OH
O
HNNBoc
CH3
NSO2
B1635
NOH
OBoc
HO
B3987
N
Boc
HO
OCH3
O
B3843
N
Boc
HO
OCH3
O
B1186
1/2H2O.OH
O
HN
CH3
CH3
Boc
B3007
xH2O.OH
O
HN
CH3
CH3Boc
B1187
H2O.OH
O
HN
CH3
CH3Boc
B2178
NH.2
OH
O
HN
HN
Boc
Boc
B3083
OH
O
HN
H2N
Boc
B1669
OH
O
HN
H2N
Boc
B1632
OH
O
HN
HN
Boc
Cbz
B3650
OH
O
CH3
NBocCH3
B3651
OH
O
CH3
NBocCH3
B2967
OH
O
HN
CH3S
Boc
B1636
OH
O
HN
CH3S
Boc
B3433
O
O
HN
CH3S N
O
OBoc
B3615
OH
O
HNBoc
B3616
OH
O
HNBoc
B3617
OH
O
HNBoc
B3376
N
C
O
O C
CH3
CH3
CH3
C
O
OH
B2253
OH
O
HN
NH
Boc
Cbz
B4141
N
O
OH
OBoc
B3945
OH
O
HNBocBr
B3613
HNBoc
OH
O
Cl
B3614
HN
OH
O
Cl Boc
Amino AcidsBioscience
Analytical Science
33This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
B4367
OH
O
HNBoc
F
B3303
OH
O
HNBocF
B3304
HN
OH
O
BocF
B3626
OH
O
HNBocF
F
B3627
OH
O
HNBocF
F
A2130
OH
O
HNBocH2N
A2131
OH
O
HNBocH2N
B3668
O
OH
HNBocO2N
B2232
OH
O
HNO2N Boc
B2989
OH
O
HNBoc
B1332
OH
O
HNBoc
B4259
OCH3
O
HNBoc
B3230
OH
O
HNBoc
B3211
OH
O
HNBoc
B4011
POCH3
CH3O
CH3O
O
HNBoc
O
B3644
N
C
O
OC(CH3)3
C
O
OH
B3700
N
C
O
OC(CH3)3
C
O
OH
B2977
NOH
OBoc
B1188
NOH
OBoc
B3414
NO
OBoc
N
O
O
B4007
C OH
O
HNBoc
HC
B4293
NOH
HNBoc
O
B4324
N
OH
HNBoc
O
E0940
N
Boc
OOCH2CH3
O
B4083
N
Boc
OH
O
O
B1863
OH
O
HN
O
Boc
B1629
OH
O
HN
O
Boc
B2205
O
O
HN
ON
O
O
Boc
B2258
OH
O
HN
HO
Boc
B1637
OH
O
HN
HO
Boc
B2073
OCH3
O
HN
HO
