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REAL-TIME SCHEDULING
REAL-TIME SCHEDULING
Biomanufacturing Software Solutions
In Use by Companies Worldwide
REAL-TIME SCHEDULING 1
SOLUTION AT-A-GLANCE
Technology leader in biomanufacturing software solutions since 2007
We are passionately dedicated to developing software solutions that transform the way in which modeling and simulation is used to improve life science processes.
Capacity Engineering & Debottlenecking
Real-Time Scheduling
Tech Transfer and Facility Fit
Software Development and Engineering
Cell and Gene Therapies
Clinical and Commercial Manufacturing
Biologics, API, and OSD
Drug Substance and Drug Product
Perfusion and Single Use
Berkeley, CA, USA
OUR PRODUCTS
REAL-TIME MODELING SYSTEM™
INTEGRATIONS FRAMEWORK
REAL-TIME SCHEDULING
BIOFIT™
AREAS OF FOCUSEXPERTISE AND SERVICESHEADQUARTERS
INDUSTRY
DIRECT INTEGRATION WITH MES/DCS
NOW
Planned Schedule Actual Schedule
AUTOMATED SCHEDULE RECONCILIATION ALWAYS FEASIBLE SCHEDULE
9:00 pm
PRO
CES
S 1
PRO
CES
S 2
PRO
CES
S 3
FUTUREPAST
MES/DCS BIO-G REAL-TIME SCHEDULING
PRESENT
REAL-TIME SCHEDULING REAL-TIME SCHEDULING 3
FULLY AUTOMATED SCHEDULING Real-Time Modeling System™ automatically schedules future operations based on automation rules by reconciling the real-time status of the manufacturing floor.
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PHASE
01PHASE
02PHASE
03PHASE
04PROJECT
COMPLETION
PHASE
051 MONTH
MODEL CONSTRUCTION
1 MONTH1 WEEK 1 WEEK
ANALYSIS, TRAINING, AND ROLLOUTPROJECT KICK OFF DATA COLLECTION AND ANALYSIS
1 MONTH
MODEL VALIDATION
ERP
QC/QA LABS
QMS
MANUFACTURING
MES/DCS
MANAGEMENT
EAM
MAINTENANCE/ CALIBRATIONS
OTHERS
WAREHOUSEAU
TOM
ATIO
N A
ND
EN
TERP
RISE
SYS
TEM
S
R E A L- T I M E
RTMSM O D E L I N G
S Y S T E M
REAL-TIME SCHEDULING REAL-TIME SCHEDULING 5
TYPICAL PROJECT TIMELINE—3.5 MONTHS:
UNIFIED SITE-WIDE SCHEDULING PROVIDES UNIFIED SCHEDULING FOR ALL DEPARTMENTS:
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Devens, MA, USA
ACHIEVEMENTSACHIEVEMENTS
Bulle, Switzerland
Multiproduct cGMP Bacterial Fermentation Facility
Large-scale Biologics Manufacturing
FACILITY DESCRIPTIONFACILITY DESCRIPTION
REAL-TIME SCHEDULING REAL-TIME SCHEDULING 7
The Bio-G scheduling tool was essential to maintaining maximum run rate and ensuring smooth coordination between departments.”
CASE STUDY
Ramping-up to Maximum Plant Capacity Using Simulation and Scheduling Tools
Sustained max run rate after ramp-up
Centralized, transparent schedule consulted by 60+ personnel in 6+ departments
Modeled buffer replenishment policies resulted in 94% reduction in scheduling durations
Maintenance activities scheduled with no impact to production flow
CLIENT
sustainable capacity increase within two months
INCREASED campaign success rate
Our planning confidence is significantly improved with Bio-G. We have been able to reduce two days of unplanned downtime year-to-date.”
CASE STUDY
Creating Value through Scheduling, Capacity Analysis, and System Integration
Bio-G Schedule saves a supervisor over one hour per shift
95% reduction in Maintenance Planning time and headcount
Cost and cycle time efficiencies in buffer preparation
Reduced downtime for column packing operations
CLIENT
MULTI-DAY INCREASE in facility uptime
RESULTS AND OUTCOMES RESULTS AND OUTCOMESFACILITY LOCATIONFACILITY LOCATION
44%
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Vevey, Switzerland
ACHIEVEMENTS
Large-Scale, Multi-Product Biologics Manufacturing
FACILITY DESCRIPTION
REAL-TIME SCHEDULING
CASE STUDY
End to End Planning System Implementation
Automatic real-time rescheduling
Adherence to Schedule Tracking and Reporting
Production and maintenance conflict prevention
Weekly/daily utilities and labor forecasts
Facilitating strategic decision making
CLIENT
END-TO-END VISIBILITY and coordination of entire production
RESULTS AND OUTCOMESFACILITY LOCATION
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ADDRESS1250 Addison Street, Suite 107 Berkeley, CA 94702
T +1.510.704.1803
F +1.510.704.0569
CONTACT USLet us know if you have questions, an upcoming project, or would like to setup a software demonstration.
Let’s have a conversation
Simulating the site: a dream for various stakeholders.”
Vevey, Switzerland
ACHIEVEMENTS
Large-Scale, Multi-Product Biologics Manufacturing
FACILITY DESCRIPTION
REAL-TIME SCHEDULING
CASE STUDY
End to End Planning System Implementation
Automatic real-time rescheduling
Adherence to Schedule Tracking and Reporting
Production and maintenance conflict prevention
Weekly/daily utilities and labor forecasts
Facilitating strategic decision making
CLIENT
END-TO-END VISIBILITY and coordination of entire production
RESULTS AND OUTCOMESFACILITY LOCATION
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Let’s have a conversation
ADDRESS1250 Addison Street, Suite 107 Berkeley, CA 94702
T +1.510.704.1803
F +1.510.704.0569
CONTACT USLet us know if you have questions, an upcoming project, or would like to setup a software demonstration.
Simulating the site: a dream for various stakeholders.”
Asia Pacific: +65 6777 8211
Europe, Middle East: +41 41 768 6111
General Inquiries: [email protected]
North America, Latin America: +1 800 833 8314 or +1 512 832 3774
Emerson
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