1585 Industrial Road San Carlos, CA 94070 USA Phone : +1 650 620 9253 Fax : +1 650 620 0093 50-B, II Phase Peenya Industrial Area Peenya, Bangalore 560058, India Ph: +91-80-28378693/5 Fax: +91-80-41172451 E-mail: [email protected]Web: www.reametrix.com “ReaMetrix help us in keeping our commitment in offering tests at affordable costs especially HIV. We have so far conducted hundreds of tests and have obtained accurate and reproducible results. The availability of these reagents at this very af- fordable price point has allowed us to significantly reduce the cost of these tests to the patient.” Dr. Sujay Prasad, Director, Anand Diagnostics “With the new concept of dried reagents a sample can be added to the reagent tube where the sample is collected. The sample integrity is maintained upto a week at temperatures upto 40°C. This gives us tremendous flexibility in the way samples can be handled.’ Dr.Anjali Kale, Head Reference Laboratory, Dr Lal Pathlabs ISO 9001:2008 certified company www.reametrix.com ReaMetrix Accelerating Innovation
“ReaMetrix help us in keeping our commitment in offering tests at affordable costs especially HIV. We have so far conducted hundreds of tests and have obtained accurate and reproducible results. The availability of these reagents at this very af-fordable price point has allowed us to significantly reduce the cost of these tests to the patient.”
Dr. Sujay Prasad, Director, Anand Diagnostics
“With the new concept of dried reagents a sample can be added to the reagent tube where the sample is collected. The sample integrity is maintained upto a week at temperatures upto 40°C. This gives us tremendous flexibility in the way samples can be handled.’
Dr.Anjali Kale, Head Reference Laboratory, Dr Lal Pathlabs
ISO 9001:2008 certified company
www.reametrix.com
ReaMetrixAccelerating Innovation
Company
ReaMetrix, Inc. is a next generation biotechnology company that was founded with the unique business model of using the “labor cost arbitrage” through India to create signifi-cant and sustainable “value arbitrage”. As with the early Silicon Valley entrepre-neurs, we are working to build a company culture that provides talented Indian scientists with an environment where they have freedom to exercise their train-ing, skills and imagination while building corporate value. Our egalitarian approach allows us to encourage and reward initiative throughout our organization. Our people are the key to our success.
“The challenge of technological inno-vation is to create solutions that are locally affordable and sustainable in the long run within the local macro-economic constraints. The solutions should permit generation of local economic activity that will reinforce long-term economic sustainability.”
Bala S. Manian, CEO ReaMetrix Inc.. Affordable Diagnostics—Chang-ing the Paradigm in India. Cytometry Part B (Clinical Cytometry) 74B (Suppl. 1):S117–S122 (2008)
Process is our Product
At ReaMetrix, we have built a world-class research and devel-opment facility in Bangalore, India with a primary focus of applying Six Sigma product de-velopment strategies to diagnos-tic and life science products. We believe that process control is a critical component of generating high quality data and products. Our corporate infrastructure is process-centric, and we live by our philosophy on a daily basis. Rigorous documentation, full audit trails, and a dedicated quality group result in high qual-ity products, and reproducible, trustworthy data. At ReaMetrix, Process is our Product.
ReaMetrix is committed to becoming the leading provider of high quality research and diag-nostic assay solutions resulting in a transformation of the cost opportunities available in India into value for both the biotech-nology and global health sectors.
HIV Immunophenotyping
Reagents for Diagnostic Use
Catalog Number
Product/ Reagent
Intended Use
Format Storage Kit Sizes
25118-00 Dry Tri T-STATCD3/CD4/CD8 Reagent *
Dry Room Temperature
50For determining absolute counts of human total T, helper/inducer & suppressor/cytotoxic T lymphocytes in erythrocyte-lysed whole blood
25197-00 Dry Tri T-STATCD3/CD4/CD45 Reagent
Dry Room Temperature
50For determining absolute lymphocyte count (ALC), percentages & absolute counts of hu-man total T and helper/inducer T lymphocytes in erythrocyte-lysed whole blood
25239-00 ReaPan 34845 Reagent
Dry Room Temperature
50For determining ALC, percentages and absolute counts of human total T, helper/inducer & Suppressor/cytotoxic T lymphocytes in eryth-rocyte-lysed whole blood
25244-00 ReaPan 3 4 G Reagent
Dry Room Temperature
50Reagent For determining absolute counts of human total T, helper/inducer T lymphocytes on Guava Platform
25332-00 ReaPan 3 8 G Reagent
Dry Room Temperature
50For determining absolute counts of human total T, suppressor/cytotoxic T lymphocytes on Guava Platform
25124-00 Rea T-Count CD4/CD3 & CD8/CD3 (Dual tube) Reagent
Dry Room Temperature
50For determining absolute counts of human to-tal T, helper/inducer & suppressor/cytotoxic T lymphocytes in erythrocyte-fixed whole blood on BD FACSCount™ platform
25242-00 Rea T Count CD4/CD3 (Single Tube) Reagent
Dry Room Temperature
50For determining absolute counts of human total T, helper/inducer T lymphocytes in erythrocyte-fixed whole blood on BD FACSCount™ platform
Decentralized Staining Concept
Blood samples from collection centres that operate in resource poor settings, age by the time as they are shipped to centralized testing facilities. CD receptors are known to undergo a process called “capping” (internalization of receptors), with sample ageing.
Dry reagents enable staining to be done in collection centres that typically have no electricity to run refrigeration units. Stained samples can then be transported without the need for cold chain.
The decentralized approach to sample processing mitigates the risk associated with variation in cell counts. Studies on samples stained and fixed using dry re-agents have shown that there is no drop in staining intensity or cell count upto 8 days when stored at room temperature.
Regulatory Status
ReaMetrix Reagents conform to highest international standards of quality. Most of the diagnostic reagents are CE marked and/or FDA cleared. For details, please contact us.
* For In Vitro Diagnostic Use in the United States
Reagents for Diagnostic Use
25238-00 ReaPan B27
Dry Room Temperature
25For detection of HLA-B27 antigen expression in erythrocyte-lysed whole blood (LWB) using flow cytometry
25323-00 ReaPan S34
Dry Room Temperature
25For enumeration of Hematopoietic stem cells CD34+ in human peripheral or mobilized blood samples, umbilical cord blood samples, bone marrow samples and leukapheresis samples by flow cytometry
25329-00 ReaPan Micro
Dry Room Temperature
50For screening of Urine samples for presence/absence of bacteria by flow cytometry
25108-00 ReaCountTubes
Dry Room Temperature
50Absolute Counting Fluorescent Beads-Provides absolute counts for immunophenotyping
Catalog Number
Product/ Reagent
Intended Use
Format Storage Kit Sizes
Hematopoietic CD34+ Stem Cell Enumeration
Presence/Absence test for Bacteria in Urine
ReaCount Tubes
HLA B-27 Typing
ReaPan S34: Ease in Workflow
ReaMetrix Stem cell enumera-tion reagents are provided in one ready-to-use reagent dried tube. The assay just needs addition of sample, simplifying sample preparation. Incubation time is 30 minutes, speeding time to results; a boon to diagnostic labs that process multiple samples simulta-neously. Predispensed fluorescence reference beads included in the reagent tube, ensure accurate enumeration of CD34+ cells interest. The result: more efficient workflow and greater confidence in results.
The only existing flow cytometry based reagent featuring two antibodies against the HLA-B27 antigen. The result: increased Sensitivity. The reagent use anti-B7 antibody against HLA-B7 antigen, which ensures minimal cross reac-tivity thus reducing the number of false positives. The result: higher Specificity. The reagent uses built-in intensity controls in each test making the assay highly ro-bust and independent of external standards.
Regulatory Status
ReaMetrix Reagents conform to highest international standards of quality. Most of the diagnostic reagents are CE marked and/or FDA cleared. For details, please contact us.
Reagents for Research Use
25347-00 Anti CD3-Atto488/CD4-PE-DyLight 594/CD8-PE/CD45-PerCP Reagent
Dry Room Temperature
50For determining ALC, percentages and absolute counts of human total T, helper/inducer & Suppressor/cytotoxic T lymphocytes in erythrocyte-lysed whole blood on Beckman Coulter 4 colour EPICS-XL Instrument
25384-00 Anti CD45-Atto 488/ CD4-PE reagent
Dry Room Temperature
50For determining ALC, percentages and absolute counts of human helper/inducer T lympho-cytes in erythrocyte-lysed whole blood
25348-00 Anti CD41-Atto488 & CD61-Atto488 reagent with Absolute Counting Beads
Dry Room Temperature
50For determining absolute counts of human platelets in stained-fixed whole blood
25387-00 7-Amino-actinomycin D ( 7-AAD) nucleic acid dye ready-to-use solution with Absolute Counting Beads
Liquid 2-8 ° C 25For enumeration of residual leucocytes in Leuco reduced blood products
25381-00 Anti CD235ab-Dy649/Thiazole Orange re-agent with Absolute Counting Beads
Dry Room Temperature
50For determining percentages and absolute counts of human reticulocytes and absolute count of erythrocytes using Flow Cytometry
Catalog Number
Product/ Reagent
Typical Usage
Format Storage Kit Sizes
Human Platelets Enumeration
Residual Leucocytes Enumeration
Human Reticulocyte Enumeration
HIV Immunophenotyping
Reagents for Research Use
CR70002-00
CR70003-00
CR70004-00
CR70005-00
CD45-PerCP/ CD55-PE
CD45-PerCP/ CD59-Atto488
CD45-PerCP/ MIgG1,k-PE
CD45-PerCP/ MIgG2a,k-Atto488
Liquid 2-8 °C 25For Paroxysmal Nocturnal Haemo-globinuria Diagnosis by Granulocytes and/or Erythrocyte Analysis using Flow Cytometry
25341-00 Anti CD45-Atto488/CD14-PE reagent with Absolute Counting Beads
Liquid 2-8 ° C 25For determining absolute counts & percent-ages of human monocytes in erythrocyte-lysed whole blood
CR70001-00 Anti CD11b-Atto488/CD64-PE/CD15-PE-Dy649 reagent with Absolute Counting Beads
Liquid 2-8 ° C 25For measurement of neutrophil CD64 expres-sion on human blood leukocytes which cor-relates with the presence of infection or sepsis in humans
Catalog Number
Product/ Reagent
Typical Usage
Format Storage Kit Sizes
Human Monocytes Enumeration
Sepsis Panel
Paroxysmal Nocturnal Haemoglobinuria (PNH) typing
Reagents for Research UseReaMetrix Multicolor Immunophenotyping Reagents (Leukemia-Lymphoma Panel)
Using its own unique dried down reagent technology, ReaMetrix can mix and match antibodies and fluorophores to create specific multicol-or dried down L-L panels of reagents as per customer’s requirements.
Minimum pack size depends on
CUSTOM CONJUGATION SERVICES
Antibody-dye combination chosen
Excitation Laser (nm)
Emission Maximum (nm)
488 488 , 532 488 , 532 488 , 532523 578 618 676
AntibodiesAtto-488(FITC Equivalent)
Phycoerythrin (PE)
PE-DyLight 594(PE-Texas Red equivalent)
PE-Dyomics 649(PE-Cy5 equivalent)
CD55
CD56
CD59
CD61
CD64
CD73
CD79a
CD90
CD103
CD105
CD117
HLA-DR
Kappa
Lambda
IgM
TCR αβ
TCR γδ
MPO
FMC7
Mouse IgG1, κ
Mouse IgG2a, κ
Mouse IgG2b, κ
Mouse IgG3
25855-01
25856-01
25859-01
25861-01
25864-01
25873-01
25879-01
25890-01
25903-01
25905-01
25917-01
25750-01
25751-01
25752-01
25753-01
25754-01
25755-01
25756-01
25757-01
25758-01
25759-01
25760-01
25761-01
25855-02
25856-02
25859-02
25861-02
25864-02
25873-02
25879-02
25890-02
25903-02
25905-02
25917-02
25750-02
25751-02
25752-02
25753-02
25754-02
25755-02
25756-02
25757-02
25758-02
25759-02
25760-02
25761-02
25855-08
25856-08
25859-08
25861-08
25864-08
25873-08
25879-08
25890-08
25903-08
25905-08
25917-08
25750-08
25751-08
25752-08
25753-08
25754-08
25755-08
25756-08
25757-08
25758-08
25759-08
25760-08
25761-08
25855-03
25856-03
25859-03
25861-03
25864-03
25873-03
25879-03
25890-03
25903-03
25905-03
25917-03
25750-03
25751-03
25752-03
25753-03
25754-03
25755-03
25756-03
25757-03
25758-03
25759-03
25760-03
25761-03
488 595, 633, 635, 647
595, 633, 635, 647
488, 532, 561
678660 660
785
PerCP APCPE-HiLyte 750(PE-Cy7 equivalent)
APC-HiLyte 750(APC-Cy7 equivalent)
25855-04
25856-04
25859-04
25861-04
25864-04
25873-04
25879-04
25890-04
25903-04
25905-04
25917-04
25750-04
25751-04
25752-04
25753-04
25754-04
25755-04
25756-04
25757-04
25758-04
25759-04
25760-04
25761-04
25855-05
25856-05
25859-05
25861-05
25864-05
25873-05
25879-05
25890-05
25903-05
25905-05
25917-05
25750-05
25751-05
25752-05
25753-05
25754-05
25755-05
25756-05
25757-05
25758-05
25759-05
25760-05
25761-05
25855-06
25856-06
25859-06
25861-06
25864-06
25873-06
25879-06
25890-06
25903-06
25905-06
25917-06
25750-06
25751-06
25752-06
25753-06
25754-06
25755-06
25756-06
25757-06
25758-06
25759-06
25760-06
25761-06
25855-07
25856-07
25859-07
25861-07
25864-07
25873-07
25879-07
25890-07
25903-07
25905-07
25917-07
25750-07
25751-07
25752-07
25753-07
25754-07
25755-07
25756-07
25757-07
25758-07
25759-07
25760-07
25761-07
Pack Sizes
This concept is suited to diagnostic labs that process multiple samples simultaneously. This approach can be used to standardize panels (anti-bodies and fluorophores) across various laboratories so that there can be an unbiased discussion of the results of immunophenotyping.
Reagents for Research UseReaMetrix Multicolor Immunophenotyping Reagents (Leukemia-Lymphoma Panel)
CUSTOM CONJUGATION SERVICES
Minimum pack size depends on Antibody-dye combination chosen
Fixative solution intended for the fixation of cell preparations
ReaFlow LiquidTemperature
4 cans (each 5 l)
Buffered sheath fluid meant for use on most flow cytometer systems.
50 ml
25386-00 Room
(Diluent Solution)Diluent solution used for dilution of Fixative solution
Other Services
Design of Research Reagents
Custom Conjugation Services
Custom Cell Line Development Services
Bead Based FLISA Assay Bead Based FLISA for Quantita-tive Estimation of Antigen Con-centrations by Flow Cytometry technique
ReaMetrix offers custom conjugation services in Antibody, proteins, Chemokines, micro and nanosphere conjugations with fluorophores and Quantum dots
ReaMetrix offers development of stable cell lines expressing protein of interest at high, homogenous levels
Detection of PCR Products on Flow Cytometry Assay
Qualitative Detection of PCR Products on Flow Cytometry
ReaMetrix can customize Antibody-Dye combinations to meet your requirements
We provide a complete development solution from, the cloning of novel genes into suitable expression vectors, transfection optimization, stable clone isolation
