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Regionalizing Health Care:Volume Standards vs.
Risk-Adjusted Mortality Rate
Laurent G. Glance, M.D.Associate Professor
Department of Anesthesiology
This project was supported by a grant from the Agency for Healthcare and Quality Research (R01 HS 13617)
Team members
Laurent G Glance, MD (University of Rochester)
Turner M. Osler, MD (University of Vermont) Dana B. Mukamel, PhD. (University of
California, Irvine) Andrew W. Dick, PhD (RAND)
Project officer
Yen-Pin Chiang, PhD
Scope of the Problem
Between 44,000 and 98,000 deaths each year due to medical errors.
National Agenda to Improve Patient Safety
AHRQ-sponsored report designated “localizing specific surgeries and procedures to high-volume centers” as a High Priority area for patient safety research.
Making Health Care Safer: A Critical Analysis of Patient Safety Practices. Evidence Report/Technology Assessment: Number 43. AHRQ Publication No. 01-E058, July 2001. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/ptsafety/
Hypotheses
Selective Referral: Selectively referring high-risk surgery patients to high-quality centers will lead to better population outcomes than selectively referring patients to high-volume centers.
Selective Avoidance: Diverting high-risk patients from low quality centers will lead to better population outcomes than diverting patients from low-volume centers.
Data
HCUP California SID (1998-2000) Administrative data (ICD-9-CM codes)
30 diagnoses 21 procedures POA indicator
Study Populations CABG PCI AAA surgery
Model Development
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Random-Intercept model Demographics
Age, gender, transfer status, admission type (elective vs. non-elective)
Comorbidities Disease Staging Elixhauser Comorbidity Algorithm
Hospital “Quality”
Hospital intercept term
Identification of High-Volume and Low-Volume Centers
High-Volume based on Leapfrog Criteria AAA > 50 cases/yr CABG > 450 cases/yr PCI > 400 cases/yr
Low-Volume Lower volume quartile
Estimating Impact of Regionalization
Added binary variable to base model to indicate whether a patient was treated at a high-volume center
Simulated mortality rate Estimated mortality rate for patients diverted to
high-volume centers Observed mortality rate for patients already
treated at high-volume centers
Volume-Outcome Association
Hospital volume is NOT a good proxy for Hospital Quality
Impact of Regionalization
Findings
Selective Referral High-Volume Centers: 0-20% mortality reduction
& 70-99% hospital closure High-Quality Centers: 50% mortality reduction &
90-99% hospital closure Selective Avoidance
Low-Volume Centers: 0-2.5% reduction in mortality & 25% hospital closure
Low-Quality Centers: 2-5% mortality reduction & 1-8% hospital closure
Policy Implications
Hospital Volume is a POOR Quality Indicator & should not be used as the basis for selective referral or selective avoidance
Selective Referral to High-Quality Centers is NOT PRACTICAL
Selective Avoidance of Low-Quality Centers may achieve modest reductions in mortality
Consider Improving Overall Hospital Quality
Quality Improvement based on Feedback of
Risk-Adjusted Outcomes
NSQIP
NNE
NSQIP
27% decrease in mortality 45% decrease in morbidity No change in casemix
Khuri. Arch Surgery 2002.
NNE Cardiovascular Study
O’Connor GT. JAMA 1996.
Current Project
Project OfficerMichael Handrigan, PhD
Hypothesis
Providing trauma and non-trauma centers with information on their risk-adjusted outcomes will lead to improved outcomes.