1. RegistrationShop:An Interactive 3D Medical Volume Registration SystemNoeska N. Smit1, Berend Klein Haneveld1,Marius Staring2, Elmar Eisemann1,Charl P. Botha3 and Anna Vilanova11 Computer Graphics and Visualization group, Intelligent Systems, TU Delft, The Netherlands2 Division of Image Processing, Department of Radiology, LUMC, The Netherlands3 vxlabs, South AfricaRegistrationShop Noeska Smit

2. Pre- and post treatmentRegistrationShop Noeska Smit 3. Multiple modalitiesRegistrationShop Noeska Smithttp://www.osirix-viewer.com/Snapshots.html 4. Atlas-based SegmentationRegistrationShop Noeska Smit 5. RegistrationRegistrationShop Noeska Smit 6. Registration Functionality AMIDE AMILab FusionSync Ezys Elastix MITK Mirada Medical PMOD Slicer VolView Voreen RegistrationShop Noeska Smit 7. SlicerRegistrationShop Noeska Smit 8. ElastixRegistrationShop Noeska Smit 9. Comparison Typically only 2D visualizations of the registration result ormissing required transformation tools Not always suitable for non-image processing expertsRegistrationShop Noeska Smit 10. What if simple interaction techniques + real-time 3D visual feedback = simplified registration process for noviceusers?RegistrationShop Noeska Smit 11. Landmark placementCorresponding landmark pairs: Method 1: surface pickerRegistrationShop Noeska Smit 12. Landmark placementCorresponding landmark pairs: Method 1: surface picker Method 2: two-step pickerRegistrationShop Noeska Smit 13. Simple visualization techniquesDirect volume rendering:Double thresholds MIPRegistrationShop Noeska Smit 14. Multi-volume renderingReal-time visual feedback on the current registrationresult:THR/THR MIP/THR MIP/MIPRegistrationShop Noeska Smit 15. RegistrationShopRegistrationShop Noeska Smit 16. Implementation Source code freely available via GitHub: github.com/berendkleinhaneveld/Registrationshop Installable builds coming soon!RegistrationShop Noeska Smit 17. RegistrationShopRegistrationShop Noeska Smit 18. Evaluation Four domain experts: Medical radiation therapist Radiologist Medical imaging researcher: + registration frequency Medical imaging researcher: - registration frequency Two use-cases: CT lung Full body MRIRegistrationShop Noeska Smit 19. Evaluation Setup1. Prior experience interview2. Live demo: artificial dataset3. Performing registration ofclinical datasets4. SurveyRegistrationShop Noeska Smit 20. Evaluation Results 3D visualizations Transformation tools Conclusion: RegistrationShop: a promising volume registration toolwith the potential to make registration more accessible toclinicians and researchers in the future.RegistrationShop Noeska Smit 21. Future Work Visualizing registration quality Visualizing non-rigid registration deformation field Experimenting with compositing operations andtransfer function definitions Examining clinical potential in larger follow-up userstudyRegistrationShop Noeska Smit 22. Conclusion RegistrationShop: medical volume registrationsystem Simple transformation techniques: manual and landmark transformations Instant visual feedback: 2D/3D inspection of current registration resultRegistrationShop Noeska Smit 23. Acknowledgements This work is supported by theTechnology Foundation STWvia project 10903:High-definition Atlas-basedsurgical planning for Pelvic Surgery CT lung datasets shown in this presentation areavailable from the Elastix test suite We would like to thank our collaborators anddomain experts for their participation in the userstudyRegistrationShop Noeska Smit 24. Thank you!@_Noeska_ , @berendkleinhane@medvisorg github.com/berendkleinhaneveld/RegistrationshopRegistrationShop Noeska Smit