7/29/2019 Report Addison Padilla
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Review :
In 1855, Thomas Addison,an Englishphysician,provided the first clinical detailed
description of the disease.
Also known as adrenal insufficiency.
An endocrine disorder characterizedby inability of adrenal gland to produce
enough of its hormone.
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Adrenal Cortex (Layers)
Zona Glomerulosa
Zona Fascicularis
Zona Reticlaris
Aldosterone
Cortisol
Androgen
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Addison’s Disease
-Adrenal Glands do not produce sufficient
steroid hormones.(glucocorticoid and
mineralcorticoid)
-Occurs at any age(most common in adults age of 60.
-Most common in woman
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Causes :
Autoimmune destruction of adrenals. Tuberculosis
Abrupt withdrawal from long-term,high steroid therapy
Surgical removal of both adrenal glands or infection.
Cancer of adrenals, Aids
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Pathophysiology: Addison’s disease
Autoimmune destruction
of adrenals. Tuberculosis
Abrupt withdrawal from long-term,high steroid therapy
Surgical removal of both adrenal glands or infection.
Cancer of adrenals, Aids
Results to massive destruction of adrenal gland
Leads to rapid decline in steroid hormones
cortisol and aldosterone
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Cortisol
Decrease secretion
of glucocorticoid
Decrease bld.glucose
Leads to Hypoglycemia
Aldosterone
Decrease secretion of
mineralcorticoid
Affects the ability of the
Distal tubules of the
nephron to conserve
Sodium
Sodium loss
Decrease Na+ leveldehydration
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S/Sx
Fatigue ,muscle weakness
Anorexia,nausea and vomiting.wt.loss
Hypoglycemia
Bronze pigmentation
Inability to cope with stress
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Diagnostic Studies
Cortisol level blood test
X-ray of Adrenal gland
Blood glucose level ACTH level
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Nursing Diagnosis :
Deficient Fluid Volume
Activity Intolerance
Knowledge Deficit
Disturbed body image
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Management :
Administration of fluids and corticosteroid.
Antibiotic for infection.
Monitor Vital signs,I and O Monito wt.
Monitor Urine and Blood glucose.
Rest
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Addisonian Crisis
Is a life-threatening response to acute
adrenal insufficiency.
This response occur in any person withaddison’s disease.
Most commonly precipitated by major
stressors,especially if the disease is poorly
controlled.
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Risk Factors for adenal crisis:
Patient who do not respond to hormone
replacement therapy.
Patient who experience extreme stress withoutadequate glucocorticoid replacement.
Abruptly stop hormone therapy
Experience trauma
Undergo bilateral adrenalectomy
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Addisonian crisis have any of the manifestationof addison’s disease.
Primary symptoms are
High fever
Weakness and fatigue Abdominal pain
Severe hypotension
Circulatory collapse
Shock
Coma
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Treatment :
Rapid intravenous replacement of fluids
and corticosteroid. Fluid balance is usually restored in
4 to 6 hours.
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Question :
1.A client is admitted into the emergencydepartment with Addisonian crisis.Which
of the following should the nurse be prepared
to administer to assist the client?
a.Thyroid replacement hormone
b. Intravenous fluids
c. Blood transfusion
d. Warm blankets
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2. Which statement illustrates that the client with
Addison’s disease understands your teaching?
a.”I wonder why I look suntanned all the time.”
b.”I will stop taking my medications when I have
an infection.”
c.”I know I should never alter my dose of medication.
d.”I have purchased an emergency kit and keep it
with me all the time.”
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3. Which of the following layers of adrenal cortex
produces hormone Cortisol?
a.Zona Reticularis
b.Zona Fesicularis
c.Zona Glomerulosa
d.Zona Fascicularis
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4.A nurse know that a client with addison’s disease
has _______Sodium and Potassium_________ .
a.Increased,Decreased
b.Decreased,Increased
c.Increased,Increased
d.Decreased,Decreased
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5.The nurse knows that o ne of the risk factor
for addisonian crisis is________.
a.Advance Maternal
b.Abruptly stop hormone therapy
c.Poor nutritiond.low-socio economic status
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6-7. List 2 nursing diagnosis for Addison’s Disease.
8-10. List 3 primary symptoms of Addisonian Crisis.