Michigan Reproductive Sciences, Grand Rapids, 5/21/2010

Reproductive Sciences ProgramAt University of Michigan

Reproductive Sciences at UofM

• Focuses on research leading to an understanding of• Focuses on research leading to an understanding of reproductive biology.

Ai t d l di ti d th ti t t i f• Aims to develop new diagnostic and therapeutic strategies for diseases that result in reproduction failure and disease processes that have their origins in reproductive processes p g p pbut that are expressed later in life.

• Encourages broad multidisciplinary involvement in• Encourages broad, multidisciplinary involvement in reproductive sciences.

R d ti i t l t ’ d ’• Reproductive sciences are central to men’s and women’s health, fertility, and embryonic stem cell biology.

Existing Programsg g

• T32 - Training Grant in Reproductive Biology and Endocrinology (NCE; resubmitted)and Endocrinology (NCE; resubmitted)

• P01 - “Prenatal Programming of ReproductiveP01 Prenatal Programming of Reproductive Health and Disease”

• U10 – Reproductive Medicine Network

38 Faculty in 12 Departments in 4 Schools

RSP Expansion / Build-out

Hires:Hires:1) Sue Moenter2) Mike Lehman – Co-Director RSP3) Lique Coolen

Offer Being Made:Offer Being Made:4) Molecular Regulation of

Gonadotropes Focus

Second Interviews Pending:5) Male Reproductive Genetics6) HPG-Axis Focus

RSP Expansion / Build-out

5 New Hires in Reprod Sciences

1) 500K Start-up/position

2) 100K/yr salary/position

3) 150K/ f 33) 150K/yr for 3 yrs –Collaborative PilotProgram

4) 12K/yr for 3yrs –Annual Symposium

Reproductive DevelopmentalBiologyBiology

Bob Denver – Dev Biol, Hormones and Embryonic Development

Gary Hammer – Internal Medicine, Gonadal Stem Cells

Project #100 Takayama et al.Kenta Nabeshima – Cell & Dev Biol, Meiotic Chromatin Dynamics

Sue O’Shea – Cell & Dev Biol, Embryonic Stem Cells, y

Gary Smith – Ob/Gyn, Gamete and Embryo Development

Jason Swain – Ob/Gyn, Factors Influencing Embryo Development

O /G GMatt Wishart – Ob/Gyn, Phosphatase and Gamete Function

Yukiko Yamashita - Cell & Dev Biol, Centrosome and Stem Cells

Reproductive Endocriology and NeuroendocrinologyNeuroendocrinology

Jill Becker – Psychology, Sex Differences in Sex and Behavior

Jacinta Beehner – Psychology, Sex Hormones and Behavior

Liq e Coolen Ph siolog Ne robiolog of Se al Beha iorProject #100 Takayama et al.Lique Coolen – Physiology, Neurobiology of Sexual Behavior

Robert Kennedy – Chemistry, Nanoscale Measures of Hormones

Roland Kwok – Ob/Gyn, Transcriptional Co-Activators

Theresa Lee – Psychology – Gonadal Steroids and Biorhythms

Mike Lehman Physiology GnRH Neurons and the HPG AxisMike Lehman – Physiology, GnRH Neurons and the HPG Axis

Jairam Menon - Ob/Gyn, G-Protein Coupled Receptors

Reproductive Endocriology and NeuroendocrinologyNeuroendocrinology

Ram Menon – Pediatrics, Insulin and IGF1 in Pregnancy and Dev., g y

Sue Moenter – Physiology, GnRH and Hypothalamic Infertility

Martin Myers – Medicine, Leptin, Nutrition, and Reproduction

V th P d bh P di t i F t l O i i f R d tiVasantha Padmanabhan – Pediatrics, Fetal Origin of Reproductiveand Metabolic Disorders

Audrey Seasholtz - Biological Chem., Stress and Reproduction

Bob Thompson – Psychiatry Mol Reg of Hypothalamic FunctionBob Thompson – Psychiatry, Mol. Reg. of Hypothalamic Function

van Anders – Psychology, Androgens and Behavior NeuroEndo

Reproductive Genetics andEpigeneticsEpigenetics

Sally Camper – Human Genetics, Genetics of PituitaryTranscription Factors

Dana Dolinoy – Environmental Health Science, EnvironmentalEpigenomics

Sundeep Kalantry – Human Genetics, Epigenetic Mechanismof X-inactivationof X inactivation

Diana Robins – Human Genetics, Androgen Receptor Function

Reproductive MedicineReproductive MedicineRonald Buckanovish – Internal Med Ovarian AngiogenesisRonald Buckanovish Internal Med, Ovarian Angiogenesis

Gregory Christman – Ob/Gyn, Uterine Leiomyomas

Project #100 Takayama et al.Howard Hu - Environ Health Sci, Metal Toxicants and Pregnancy

Josephine Kasa-Vubu - Peds, Body Composition and Puberty

John Meeker - Environ Health Sci, Environ Exposure and ReprodJohn Meeker Environ Health Sci, Environ Exposure and Reprod

John Randolph – Ob/Gyn, Hormones and Menopause

Yolanda Smith – Ob/Gyn, Brain Imaging and Reproduction

Reproductive Tract Biology

Dave Aronoff – Internal Med, Immunology of Female ReprodProject #100 Takayama et al.Tract

John DeLancey – Ob/Gyn, Birth and Pelvic Floor DysfunctionJohn DeLancey Ob/Gyn, Birth and Pelvic Floor Dysfunction

Craig Harris – Environ Health Sci, Dev Reprod Toxicology

Rita Loch-Caruso - Environ Health Sci, Hox Genes and the Uterus

North Campus Research Complex

Total acreage: 173.5 acresGross Sq Ft: 1 97MGross Sq Ft: 1.97MRes. Lab Sq Ft: 1.3M

12

Anita Payne Lectureship and PosterDDay

October 15 2010October 15, 2010

Towsley Center UoM- Towsley Center, UoM

- Abstracts due Sept. 15th

- Anita Payne Lecture:Kelly E. Mayo

Department of Biochemistry, Molecular Biology & Cell Biologygy gyCenter for Reproductive ScienceNorthwestern University