Research activities of the Membrane Society of Japan

Takeo YamaguchiTokyo Institute of Technology

History1978 The Membrane Society of Japan was established

(Prof. Nakagaki, Prof. Shimizu, Prof. Kimura)1982 The European Membrane Society (EMS) was established.1984 Japan-Europe Membrane Conference (former ICOM)1987 1st ICOM (Tokyo) (Prof. Nakagaki)1996 4th ICOM (Yokohama) (Prof. Kimura)2002 1st Aseanian Membrane Society (AMS) meeting (Tokyo)

(Prof. Nakao)

Mission•To promote the advancement of science and technologies insynthetic membranes, bio-membranes and their interdisciplinaryfields.

The Membrane Society of Japan

Boards in 2017President: Hideto Matsuyama (Kobe Univ.)Vice President: Atsuo Kumano (Toyobo co ltd.)

Hiroyuki Saito (Kyoto Pherm. Univ.)Masahiro Goto (Kyushu Univ.)

Directors: Emiko Okamura (Himeji Dokkyo Univ.)Hidetoshi Kita (Yamaguchi Univ.)Hiroyoshi Kawakami (Tokyo Metro. Univ.)Mikihisa Takano (Hiroshima Univ.)Masahiko Matsukata (Waseda Univ.)Masakazu Yoshikawa (Kyoto Inst. Tec.)Mitsuru Higa (Yamaguchi Univ.)Mutsumi Inaba (Hokkaido Univ.)Shin-ichi Nakao (Kogakuin Univ.)Shuji Nakatsuka (Daicen Membrane Sys. Ltd.)Takahiro Kawakatsu (Kurita Water Ind. Ltd.)Takashi Miyata (Kansai Univ.)Takeo Yamaguchi (Tokyo Inst. Tech.)Toru Maruyama (Kyushu Univ.)Toshinori Tsuru (Hiroshima Univ.)Yoshinori Marunaka (Kyoto Pref. Univ. Medicine)

Auditors: Hidetoshi Kita (Yamaguchi Univ.)Kazuo Oki (Tohoku Univ.)

Academia (Synthetic and interdisciplinary fields)

Hiroshima Univ.Prof. Tsuru,

Assoc. Prof. Kanezashi

Tokyo Inst. Tech.Prof. Yamaguchi

Kobe Univ.Prof. MatsuyamaProf. Yoshioka

Waseda Univ. Prof. Matsukata

Kogakuin Univ.Prof. Nakao, Prof. Takaba,

Assoc.Prof. Akamatsu

Utsunomiya Univ. Prof. Itoh

AIST (Tsukuba)Dr. Hara, Dr. Yoshimune, Dr. Sumaru

Kansai Univ.Prof. Miyata

Niigata Univ.Prof. Aoki,

Prof. Tanaka

Nagoya Univ.Prof. IritaniOsaka Univ.;

Prof. Umakoshi, Prof. Nishiyama

Yamaguchi Univ.Prof. Kita, Prof. Higa, Assoc. Prof. Kumakiri

Meiji Univ. Prof. Nagai

Kyushu Univ.Prof. Goto

Prof. Taniguchi

Tokyo Metrop. Univ.Prof. Kawakami

Univ. of TokyoAssoc. Prof. Ito

Shibaura Inst. Tech.Prof. Nomura,Prof. Yoshimi

Nagoya Inst. Tech.Assoc. Prof. Nagumo

Tokyo Univ. Agr. Eng.Assoc. Prof. Ohashi

RO/ NF Toray (sw), Nitto (sw), Toyobo (sw)

UF Asahi Chemicals, Daicen

MF Mitsubishi Rayon, Asahi Chemicals

GS Ube Industries

PV

IE

Engineering Kurita, Organo, Mitsubishi Rayon

Industries

inJapanese FujiEconomics2016

Share of RO and NF membranes in 2015

Dow chemical38%

Toray26%

Nitto Denko24%

Toyobo5%

Vonton3%

GE2%

Others

Research Activity: Polymeric Membranes (Fouling)

Molecular level Polymer level Commercial level

Structure formation simulation Fouling simulation

Experimental approach (Hierarchical study)

Simulation approach

Polymer synthesis

MD simulation

Und

erstandfoulingph

enom

ena

Hideto Matsuyama (Kobe Univ.)

Shin-ichi Nakao & Kazuki Akamatsu (Kogakuin Univ.)

Research Activity: Membrane Modeling and Systems

Tomohisa Yoshioka (Kobe Univ.)

4.0nm

1.8nm

Sea water CP nanotube Pure water

MD simulation

PRO and RED system Mitsuru Higa (Yamaguchi Univ.)

Hiromitsu Takaba (Kogakuin Univ.) Ryo Nagumo (Nagoya Institute of Tech.)

Transport model and Process simulation

Takeo Yamaguchi (Tokyo Institute of Tech.)

Reverse osmosis (RO) Forward osmosis (FO)

EFO = Ed + EpEd : water recovery from draw solution

Ed = DG / QproductEp : pressure drop

ERO = 2.5 kWh / m3 water

Research Activity: Inorganic Membranes 1

γ-

α-

“Molecular Sieve” mechanism

SiO2

γ-Al2O3 :Intermediate layer (pore 4nm)

α-Al2O3Support(pore 100nm)

Largegas

H2Cross-section

Chemical Vapor Deposition (CVD) membranes

Shin-ichi Nakao & Kazuki Akamatsu(Kogakuin Univ.)

Toshinori Tsuru (Hiroshima Univ.)

104.1

Crosssection

a-Al2O3 support

SiO2–ZrO2intermediatelayer

TiO2–ZrO2–ISOHtoplayer

500nm

Sol-gel membranes

Zeolite membranes

Masahiko Matsukata (Waseda Univ.),Hidetoshi Kita & Izumi Kumakiri (Yamaguchi Univ.)

Mikihiro Nomura (Shibaura Inst. Tech.)

ZeoliteMembraneTube

SecondgroupofModule

Modulex 8

Vacuumvessel

L:80cmO.D.:1.2cm

Morethan150PVplantsfordehydrationoforganicliquidareoperatedinJapan

125tubes,3.75m2

Ex.16modules,60m2DehydrationofEtOH,9099.8wt%,600L/hat120°C,6kg/cm2

Research Activity: Inorganic Membranes 2

Photoimage

CrosssectionSEM-EDX

CuBTClayer 40μm

Aluminasubstrate

100μm

[1,1,0]

Pore-size0.35nm

Cu: O: C:

Miki Yoshimune (AIST) Nobuo Hara (AIST)

MOF membraneCarbon membrane

Research Activity: Electrolyte Membranes and Ion Exchange Membranes

Hiroyoshi Kawakami(Tokyo Metro. Univ.)

Takeo Yamaguchi(Tokyo Institute of Tech.)

0

0.2

0.4

0.6

0.8

1

1.2

0 0.5 1 1.5 2

(80℃)90℃100℃

Cel

l vol

tage

[V]

Current density [A/cm2]

Tough anion-exchange membrane

Pore-filling membrane Nano-fiber membrane

30% humidity

Research Activity: Bio-membranes

CPPsPenetratin: RQIKIWFQNRRMKWKKHIV-1 tat: GRKKRRQRRRPQoctaarginine: RRRRRRRR

1. Endocytosis

Cytosol

Glycosaminoglycan (GAG)

Lipidbilayermembrane

Membrane Permeation of Cell-Penetrating Peptide (CPP)Two Pathways of Translocation process

2. Non-endocytotictranslocation

Membrane Permeation of Cell-Penetrating Peptide (CPP)Two Pathways of Translocation process

PlausibleMechanismforNon-Endocytic,Energy-IndependentTranslocationof19F-R8intoCells

Themechanisminvolves(i) bindingof19F-

R8toGAGatthecellsurface,followedby

(ii) thetransfertothecellmembrane,and

(iii) theentryintocytosol.

Cytosol

研究背景:細胞膜の動的構造や機能の理解

Verticalfluctuation

Lateraldiffusion

Cellmembranesarethedynamicsystem.

Dynamiccellmembranes

Incorporationofionchannel proteinsalsomodifiesthemembrane.

Cholesterol

Ionchannel

MechanismofthedeliveryofdrugsandbioactivechemicalsMoleculardynamicsinthemembrane

LipidbilayermembraneCellinside outside

Prof. Emiko Okamura (Himeji Dokkyo Univ.)

Aquapoline

K. Tani and Y. Fujiyoshi et al., J. Mol. Biol. 389, 694 (2009)

Hydrophobic porePore size 3N-N distance 2.8 ±0.2

AQPs efficiently and specifically conduct waterwhile completely preventing proton permeation.

Hydrogen-bondings were cut at the pore entrance and a single water molecule can be permeated.

Research Activity: Bio-mimetic and Bio-inspired Membranes 1

Bio-membraneBio-membrane system

Pore open Pore closed

Molecular recognition gating membrane

Bio-inspiredmembrane

Takeo Yamaguchi (Tokyo Institute of Tech.)

Research Activity: Bio-mimetic and Bio-inspired Membranes 2

BPA-imprinted gel

Nonimprinted gel

Meso-ScaleUnit(Self-OrganizingSystem)

Takashi Miyata (Kansai Univ.),

Hiroshi Uamakoshi (Osaka Univ.)

Summary

• “When you join the membrane society of Japan, you canunderstand all of membrane research fields including syntheticmembranes, bio-membranes and interdisciplinary field”.

• 437 people and 34 industrial companies are belonged to the society.

• Another important mission is to gather the membrane researchersfrom different fields at one place and merge and exchange theirknowledge and information to create new membrane researchfields.

If you ask us what is The Membrane Society of Japan.

Prof. Hideto Matsuyama (Kobe University)

Prof. Toshinori Tsuru (Hiroshima University)

Dr. Masahide Taniguchi (Toray co ltd.)

Dr. Takahiro Kawakatsu (Kurita co ltd.)

Dr. Atsuo Kumano (Toyobo co ltd.)

Prof. Emiko Okamura (Himeji Dokkyo Univ.)

Prof. Takashi Miyata (Kansai Univ.)

Prof. Hiroshi Uamakoshi (Osaka Univ.)

Prof. Hiroyoshi Kawakami (Tokyo Metro. Univ.)

Prof. Tomohisa Yoshioka (Kobe Univ.)

Prof. Mikihiro Nomura (Shibaura Inst. Tech.)

Assoc. Prof. Kazuki Akamatsu (Kogakuin Univ.)

Dr. Nobuo Hara (AIST)

Acknowledgments