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Research INKlings Summer 2014

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Summer 2014 RESEARCH INKLINGS Human Performance Company Licenses a New Device, Surrobot Inside Research INKlings P2 – Dr. Patrick Flume P7 – HCC’s K12 Scholars P6 – Oral Health Symposium P3 - Human Performance Co. Licenses New Device P2 – Dr. Kathleen Brady P4/5 – IDEA Program P8 – Inventor of the Year, Dr. Steve Tomlinson P6 – Tobacco Research Scientific Retreat P7 – SCRCRS Pilot Project Program P6 – SCresearch EXPO A real world telepresence device has an exclusive license from South Carolina Science Solutions, LLC (SCSS). Robert J. Adams, MS, MD, founder of SCSS, is a MUSC Board of Trustees’ Eminent Scholar in Neuroscience, Director of the Smart State Center of Economic Excellence for Stroke and Director of REACH MUSC Tele-stroke Network. He created SCSS to implement inventions that will lead to improved outcomes, problem solving, and human performance in medical, public safety, education, and industrial domains with a special emphasis on creating jobs and high tech growth in South Carolina. SCSS is a startup company funded by Dr. Adams’ personal investment. His invention is called the “Surrobot” which refers to having a person wear the device and be a “surrogate” for one or many individuals in the field. Dr. Robert Adams, the inventor of the Surrobot, has engaged as of September 2013, Mr. Sam Havelock of Forager Group and Chad Craven of Open Source to put the Surrobot into a real clinical application. Surrobot is a wearable visor with dual head up display (HUD) and high definition (HD) camera. This telepresence device is designed to be worn by a technician who receives HUD information pertinent to the situation/scenario while also providing a real time video, audio, and data feed to one or many sets of experts located remotely. The visor is head-mounted leaving the Surrobot Technician’s hands free. The visor also partially shields the eyes from injury or contamination in hazardous environments such as battlefield, mass casualty, radiation or surgery. What was the inspiration for the Surrobot? It may appear to be obvious with the daily stories about Google Glass but Dr. Adams recalls the moment that changed his view. Dr. Adams recalls, “it was a Friday afternoon in 2011; I was attending physician for stroke consults at MUSC. Continued on page 3
Transcript
Page 1: Research INKlings Summer 2014

Summer 2014

RESEARCH INKLINGS Human Performance Company Licenses a New Device, Surrobot

Inside Research INKlings

§ P2 – Dr. Patrick Flume

§ P7 – HCC’s K12 Scholars

§ P6 – Oral Health Symposium

§ P3 - Human Performance Co. Licenses New Device § P2 – Dr. Kathleen Brady

§ P4/5 – IDEA Program

§ P8 – Inventor of the Year, Dr. Steve Tomlinson

§ P6 – Tobacco Research Scientific Retreat

§ P7 – SCRCRS Pilot Project Program

§ P6 – SCresearch EXPO

A real world telepresence device has an exclusive license from South Carolina Science Solutions, LLC (SCSS).

Robert J. Adams, MS, MD, founder of SCSS, is a MUSC Board of Trustees’ Eminent Scholar in Neuroscience, Director of the Smart State Center of Economic Excellence for Stroke and Director of REACH MUSC Tele-stroke Network. He created SCSS to implement inventions that will lead to improved outcomes, problem solving, and human performance in medical, public safety, education, and industrial domains with a special emphasis on creating jobs and high tech growth in South Carolina.

SCSS is a startup company funded by Dr. Adams’ personal investment. His invention is called the “Surrobot” which refers to having a person wear the device and be a “surrogate” for one or many individuals in the field.

Dr. Robert Adams, the inventor of the Surrobot, has engaged as of September 2013, Mr. Sam Havelock of Forager Group and Chad Craven of Open Source to put the Surrobot into a real clinical application.

Surrobot is a wearable visor with dual head up display (HUD) and high definition (HD) camera. This telepresence device is designed to be worn by a technician who receives HUD information pertinent to the situation/scenario while also providing a real time video, audio, and data feed to one or many sets of experts located remotely.

The visor is head-mounted leaving the Surrobot Technician’s hands free. The visor also partially shields the eyes from injury or contamination in hazardous environments such as battlefield, mass casualty, radiation or surgery.

What was the inspiration for the Surrobot? It may appear to be obvious with the daily stories about Google Glass but Dr. Adams recalls the moment that changed his view. Dr. Adams recalls, “it was a Friday afternoon in 2011; I was attending physician for stroke consults at MUSC.

Continued on page 3

Page 2: Research INKlings Summer 2014

Research INKlings Summer 2014

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With the recent transition in the Office of Associate Provost for Research (OAPR) and the Huron Consulting review of research administration, Dr. Mark Sothmann and Dr. Kathleen Brady considered it essential to name an Interim Assistant Provost for Research Compliance and Regulatory Affairs.

Dr. Patrick Flume has agreed to serve as the Interim Assistant Provost for Research Compliance and Regulatory Affairs. Dr. Flume is a Professor of Medicine and Pediatrics and the Powers Huggins Endowed Chair for Cystic Fibrosis. He has been with MUSC for over 20 years and received his MD degree from the University of Texas Health Sciences Center at San Antonio and completed a Fellowship in Pulmonary and Critical Care Medicine at the University of North Carolina, Chapel Hill.

In this part-time appointment, Dr. Flume will provide direct policy/strategic planning oversight of two key areas of the OAPR by working with administrative staff, the Office of Research and Sponsored Programs (ORSP) and the Office of Research Integrity (ORI). Additional duties include serving as OAPR liaison to University Compliance, Conflict of Interest, the Division of Laboratory Animal Resources (DLAR), and the Office of Grants and Contract Accounting (OGCA).

Please welcome Dr. Flume to his new role.

Dr. Mark Sothmann, Vice President for Academic Affairs & Provost, is pleased to announce Dr. Kathleen Brady, Distinguished University Professor in the Department of Psychiatry and Behavioral Sciences, and current Associate Provost for Clinical and Translational Science, as the Interim Associate Provost for Research.

In that capacity Dr. Brady will also serve as MUSC’s Chief Scientific Officer and Institutional Official. A nationally and internationally prominent researcher in the areas of drug and alcohol dependence, post traumatic stress disorder and medication development, Dr. Brady has been continuously federally funded for her research since 1989 and is currently the principal investigator of the NIH-funded Clinical and Translational Science Award at MUSC. She has been the recipient of numerous prestigious awards at MUSC and nationally.

Dr. Brady assumed her new role effective June10, 2014.

Dr. Kathleen Brady Named Interim Vice Provost for Research

Interim Assistant Provost for Research Compliance and Regulatory Affairs Appointed, Dr. Patrick Flume

Page 3: Research INKlings Summer 2014

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Human Performance Company Licenses New Device Continued from page 1

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I was getting calls from multiple locations such as Rutledge Tower, the Main Hospital and the Ashley River Tower. With precious little time and medical teams in the field, I knew we would need to lay eyes on the patients to gauge how serious the situation was in the field. A system where each team could tele present their case, with myself and the other teams watching from the nearest hospital monitor. Without the delay of walking we would have more time to discuss the cases, optimize the educational value, fold in the imaging and reduce the opportunity cost of what we do.”

Dr. Adams reveals that his new device has several advantages. One advantage is that Surrobot provides pattern recognition and rapid

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situation analysis quickly brought to bear by field-experienced consultants who see and interact with the situation (almost) first hand and in real time.

Another benefit of this device is the near limitless potential of “feed forward” data to the technician via downlink and HUD display of information relevant to the on-site situation, such as medical data, overall situation analyses from other sources (e.g. contamination risk, radiation levels, satellite views of broad field situations).

This device once realized may play a role in the Testing, Inspection, and Certification space that represents a large business opportunity. However the medical area is a logical place to start for SCSS and that is where the focus is now.

The Original Invention

22 July 2014

Forager Group, LLC Copyright 2014, All Rights Reserved

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•  Synchronous and asynchronous use of video and medical media

•  Capability gaps = Lack of ability to deliver actionable knowledge –  Emergency Response “Golden Hour” –  Home Health Care

The Original Invention

22 July 2014 Forager Group, LLC

Copyright 2014, All Rights Reserved

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•  Synchronous and asynchronous use of video and data.

•  Capability gaps = Lack of an ability to deliver more actionable knowledge to the care giver –  Emergency Response “Golden Hour” –  Home Health Care

The Original Invention, Forager Group, LLC, Copyright 2014, July 2014

RPPR Required for Non-SNAP Progress Reports

NIH currently requires use of the fed-wide progress-reporting format — known as the RPPR (Research Performance Progress Report) — to submit progress reports for Streamlined Non-competing Award Process (SNAP), fellowship, and multi-year funded awards. Now, it’s official — all type 5 non-SNAP progress reports submitted on or after October 17, 2014 need to be submitted through the RPPR module of eRA Commons.

For additional information, please contact your assigned Grant Administrator in ORSP or call 792-3838 for assistance.

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IDEA Program Offers In Depth Training for MUSC’s Community of Research Administrators

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MUSC’s Research Community has a new program designed to meet the research administration needs of our campus. The Integrated Departmental Education for Administrators (IDEA) Program was formed in the Fall of 2013, consisting of multi-central/college and departmental members in varying research administrative support roles.

The program evolved to meet the growing sponsored research community’s need for a comprehensive training program. It is designed to assist staff with building competencies and increase knowledge in all sponsored research related areas with the overall goal of increasing efficiency and effectiveness.

This program is targeted specifically to: proposal development personnel, sponsored projects administrators, grant and contract accountants, departmental administrators, research compliance administrators and others with newly acquired responsibilities in research administration.

Beth Hansell, Departmental Administrator for the Department of Pathology and Laboratory Medicine, chaired the training and professional workgroup. This workgroup with 30 plus members has been meeting weekly since September 30, 2013 to develop the class materials for content

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covering three content areas: Fundamentals, Pre-Award and Post-Award.

The curriculum includes traditional classes, interactive workshops and online instruction to enhance the learning experience.

Following an instructor orientation, the IDEA Pilot Program began July 21 and runs until September 25. This program will run for ten weeks and will be taught by a group of subject matter experts from across the MUSC enterprise.

The Pilot participants have made a commitment to attend all twelve class and provide a critique of each training class – content accuracy, subject thoroughness, as well as, offer suggestions about the overall teaching environment.

The IDEA training classes are scheduled to go live in early 2015 and will be available year round for new and recent hires, as well as, anyone needing to brush up on particular research topics. Participants will receive certificate of completion after completing all twelve IDEA classes.

For more information on this program and the classes, please visit the IDEA website.

INTEGRATED DEPARTMENTAL EDUCATION FOR ADMINISTRATORS PROGRAMIDEA

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IDEA program content areas:

Fundamentals Pre-Award Post-Awardv Research Administration

Overview

v Pre-Award Essentials

v Budget Fundamentals

v Business Practices Fundamentals

v Veterans Affairs (VA) & You

v Budget Development

v Sub-agreements

v Submission Process

v Post-Award Basics

v Research Compliance

v Closeouts/Audits

v Universal Management System (UMS)

The course curriculum in the IDEA program will be team taught by subject matter experts from the central offices and from various departments. Instructors will donate their time to the program.

An Instructor Orientation was held in July, the program instructors learned more about presentation skills, training methods and learning styles. Dr. Mary Mauldin, Professor and Executive Director, Office of Instructional Technology & Faculty Resources, led the Best Practices for Teaching session. Dr. Gretchen Seif, College of Health Professions, and Dr. Jessica Bohonowych, Foundation for Prader-Willi Research, discussed Brain Rules and Building Learning Objectives.

These university experts will teach the pilot program courses: Joseph Bennett, Jennifer Mayser-Blank, Debi Cain, Cameron Craft, Erica Ellington, Evelyn Fabunan, Karen Fulghum, James Fant, Stacey Goretzka, Beth Hansell, Kevin Hildreth, Heidi Hildreth, Wanda Hutto, Sarah Jackson, Yashmin Karten, Ed Krug, Jackie Middleton, Jen Owens, Catherine Sandifer, Royce Sampson, Debra Siler, Stephen Skelton, and Terri Wall.

Please contact Wanda Hutto ([email protected]) if you are interesting in learning more or becoming an instructor in the IDEA program.

IDEA Pilot Program Participants • Joseph Addison, College of Pharmacy• Shelli Beebe, Hollings Cancer Center• Debra Cain, SCTR• Heather Ferguson, Research Development• Carla Frichtel, Hollings Cancer Center• Kathryn Grass, Surgery• Kevin Hildreth, Pathology• Heidi Hildreth, Microbiology & Immunology• Amanda Lewis, OB/GYN• Trelle Loucks, Neurosciences/Research• Ryan Mulligan, OB/GYN

• Shaquana Randall, Public Health Sciences• Lucius Rouse, Grants & Contracts Accounting• Kim Seymour-Edwards, Biomedical Informatics

Center• Michelle Forster, Cell and Molecular Pharmacology

& Experimental Therapeutics• Victoria Simmons, Biochemistry & Molecular Biology• Jennifer Smith, Medicine• Richard White, Grants & Contracts Accounting• Stan Smith, College of Health Professions

IDEA Instructors

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Please mark your calendar for "Making Tobacco History: Accelerating Efforts to Reduce the Harm Caused by Tobacco."

The keynote speakers include John R. Seffrin, PhD, Chief Executive Officer, American Cancer Society, Inc & Jonathan M. Samet, MD, MS, Senior Editor, Surgeon General's Report 2014, Distinguished Professor and Flora L. Thornton Chair, Department of Preventive Medicine, Keck School of Medicine of University of Southern California, Director, USC Institute for Global Health, USC.

This scientific retreat will be held on October 30, 2014 in the Bioengineering Building Auditorium from 9:00-4:00 pm. A reception will follow in the Bioengineering Lobby.

The retreat is sponsored by the SCTR Institute, Hollings Cancer Center, Department of Psychiatry & Behavioral Sciences, Department of Public Health Sciences, & Flight Attendant Medical Research Institute.

MUSC's SC Clinical & Translational Research (SCTR) Institute is pleased to announce its fourth research recruitment fair – SCresearch Expo!

The SCresearch Expo is a research event that

§ Increases awareness of both general and study-specific research

§ Energizes MUSC staff, patients, and the public to partner with research as study participants

§ Celebrates research study volunteers as Partners.

Study teams campus-wide will share research opportunities and education with patients, families, visitors, employees, and students. MUSC principal investigators are strongly encouraged to attend.

The Expo will be held on October 14, 2014 from 10:30 to 2:00 pm in the Horseshoe & Portico.

SCresearch Expo

Tobacco Related Research Scientific Retreat

Oral Health Symposium

The MUSC Oral Health Symposium is planned for November 21, 2014 in the Bioengineering Building Auditorium from 9:00 to 3:00 pm. The Keynote Speaker is William Giannobile, DDS, MS, DMSc, Najjar Professor of Dentistry and Chair, Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry. Poster presentations will be held in the Bioengineering and Drug Discovery Lobbies. The Center of Oral Health Research, the College of Dental Medicine, and the SCTR Institute are sponsoring this symposium.

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SC Research Center for Recovery from Stroke (SCRCRS) is pleased to announce the release of the Request for Applications (RFA) and Submission Guidelines for the 2014-2015 funding cycle for the SCRCRS Pilot Project Program. The program will support four grant categories: Fast Forward, Mentored Investigator, Discovery Awards, and Novel Methods & Technologies. The letter of intent is due August 1, 2014 and the application due date is August 15, 2014.

SC Research Center for

Recovery from Stroke

Hollings Cancer Center Awards, New K12 Scholars The Hollings Cancer Center (HCC) Paul Calabresi Clinical & Translational Oncology Training (K12) Program trains successful, patient-oriented, clinical- and laboratory-based investigators who can work effectively in a collaborative, translational research setting. Scholars bridge the knowledge derived from both the laboratory and clinic and apply that knowledge directly to establishing new, effective cancer interventions.

The 2014-2016 awardees for the Paul Calabresi Clinical & Translational Oncology Training Program and Abney Scholars include the following:

David Neskey, MD Assistant Professor, Department of Otolaryngology – Head & Neck Surgery “Personalization of Head and Neck Cancer Care through Identification of Novel Genomic Fingerprints” John Wrangle, MD Assistant Professor, Division of Hematology-Oncology Department of Medicine “Epigenetically Reversible Immune Evasion Phenotypes & Biomarker Development in Non-Small Cell Lung Cancer”

K12/Abney Scholar Samuel Lewis Cooper, MD Assistant Professor, Department of Radiation Oncology “Impact of Smoking Cessation Program on Quality of Life in Patients Receiving Radiotherapy”

Page 8: Research INKlings Summer 2014

Summer 2014

Research INKlings is an on-line newsletter prepared by the Office of Research Development providing research news, policy changes and

other relevant information for MUSC faculty, staff and students.

Mark Sothmann, Vice President, Academic Affairs & Provost; Michael Rusnak, Executive Director, MUSC Foundation for Research Development; Stephen Tomlinson, Professor, Microbiology & Immunology; Christine Dixon Thiesing, Licensing Officer, and Jesse Goodwin, Associate Director, MUSC Foundation for Research Development.

Inventor of the Year, Dr. Steve Tomlinson

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inhibitors that are targeted to anatomical/disease sites and that specifically inhibit different complement pathways or complement activation products."

His research on the complement system has been the foundation for 23 invention disclosures and 86 patent applications in more than 19 countries. Fourteen of these filings are issued or allowed.

Dr. Tomlinson was a founder of Taligen Therapeutics. Taligen licensed several of Dr. Tomlinson’s inventions from MUSC in 2007 and was later acquired by Alexion Pharmaceuticals for $111M. A Phase 1 clinical trial was initiated for one of the licensed compounds.

To learn more about technology transfer, please visit the Foundation for Research Development webpage.

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The Foundation for Research Development (FRD) at the MUSC has announced the recipient of its annual Inventor of the Year award, Dr. Steve Tomlinson. Dr. Tomlinson will be recognized and presented with a plaque to honor his achievements at the next FRD Board Meeting.

Dr. Tomlinson is a Professor in the Department of Microbiology and Immunology. Dr. Tomlinson received his Bachelors of Science in Microbiology from Leeds University, his PhD in Clinical Biochemistry from University of Cambridge, and did his Postdoctoral work at the University of Florida in Molecular Biology. He joined MUSC in 2000.

He stated that, "research activities in my laboratory are focused on the biology of the complement system, with an emphasis on the role of complement in inflammatory processes, allo-immunity and tumor immunity. We have pioneered the development of complement


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