22
Resident ResearchDepartment of Internal Medicine
Ted Mikuls, MD, MSPH
Umbach Professor of Rheumatology
Vice Chair, Research
(402) 559-8168 (Karla)
Maria Daniels
Research Program Associate
(402) 559-4875
Industry, $8,781,872.00, 38%
NIH, $1,434,500.00,
6%Other Extramural,
$2,397,498.00, 11%
Other Fed, $8,181,128.00, 36%
VA, $2,028,221.00, 9%
2017 Departmental Grants by Type
Industry
NIH
Other Extramural
Other Fed
VA
TOTAL: $26,217,637
0
50
100
150
200
250
300
350
400
450
2011 2012 2013 2014 2015 2016 2017
Departmental Publication Trends
Total
Why?
• It’s required (sorry fellows…)
• Helps build clinical skill set
• Satisfy your intellectual curiosity; answer your own questions
• Helps you read the literature
• Diversification
• CV-builder (fellowship applications)
• Interaction with faculty
• Fame and glory
• Free food
Internal Medicine Research Council Members
Ted Mikuls, MD, MSPH, IMRC Chair
Muhamed Baljevic, MD, Oncology/Hematology
Thuy Koll, MD, Geriatrics/Gerontology
Jennifer Harsh, PhD, General Internal Medicine
Paul Thomes, PhD, Gastroenterology/Hepatology
Dahn Clemens, PhD, Gastroenterology/Hepatology
Andre Kalil, MD, MPH, Infectious Diseases
Kristina Bailey, MD, Pulmonary, Critical Care, Sleep and Allergy
Andrew Goldsweig, MD, Cardiology
Benita McVicker, PhD, Nephrology
Vijay Shivaswamy, MBBS, Diabetes, Endocrinology, & Metabolism
Bryant England, MD, Rheumatology/Immunology
Rachel Thompson, MD, General Internal Medicine, Hospitalist Med.
Brett Henderson, Resident Representative
Kaitlyn Brittan, Resident Representative
Tate Johnson, Resident Representative
Angie Peppers, Vice Chair for Finance and Administration
Maria Daniels, Research Program Associate
Resident ResearchIt can be done! And done well…
• Neil Bhogal, Eichele D, Bhat I, Singh S, et al. Needle-Knife Fistulotomy for the Rescue: An Unusual Cause of Iatrogenic Extrahepatic Biliary Obstruction. Case Reports in Gastrointestinal Medicine. Jan. 2018
• Kaitlyn Brittan, O'Dell JR, Mikuls TR, et al. Comparative effectiveness in gout trial. Contemp Clin Trials. May 2018
• Mathew Day, Nathan Anderson, et al. Coxsackie Myocarditis and Hepatitis with Reactivated Epstein-Bar Virus: A Case Report. Am J of Case Reports. Feb. 2017
• Lyndsey Heise, et al. Zika and pregnancy: A comprehensive review. Am J Reprod Immunol. Feb. 2017
• Dina Ahmad, Khalid Sahak, Audrey Lazenby, Ishfaq Bhat, Chronic mesenteric ischemia and gastric ischemia: A bad combination. J of Gastrointestinal Endocscopy, Sept. 2017
Resident ResearchIt can be done! And done well…
• Wunschel J, Poole JA. Intrauterine contraception and chronic urticarial: a case series. Ann Allergy Asthma Immunol 2017 [In Press].
• Wunschel J, Poole JA. Occupational agricultural organic dust exposure and its relationship to asthma and airway inflammation in adults. J Asthma 2016; 53: 471-7
• Peper SM et al. Rheumatoid arthritis treatment after methotrexate: triple therapy is more durable than etanercept. Arthritis Care Res 2017 [Epub ahead of print].
• Antoniak D et al. Aldehyde-modified proteins as mediators of early inflammation in atherosclerotic disease. Free Radic Biol Med 2015; 89: 409-18.
• Rorie A et al. Beneficial role for supplemental vitamin D3 treatment in chronic urticarial: a randomized study. Ann Allergy Asthma Immunol 2014; 112: 376
• Chakraborty S, et al. Surgical resection improves survival in pancreatic cancer patients without vascular invasion – a population based study. Ann Gastroenterol 2013; 26: 346
• England BR et al. Validation of the rheumatic disease comorbidity index. Arthritis Care Res 2015; 67: 865
Ongoing Resident Projects• Effect of renin-angiotensin inhibitors on outcomes
after transcatheter aortic vale replacement• Brent Klinkhammer (Goldsweig)
• Optimizing Care of Patients with Cirrhosis and Ascites
• Brett Henderson (Eichele)
• Correlation Between Inflammatory Markers and Coronary Artery Flow
• Cason Christensen (Dan Anderson)
• Mechanisms of Proteasome Action in Pathophysiology of Liver Disease
• Laura Vance (Casey and Thomes)
• You Breathe How You Eat• Letisha Ferris (Poole)
• Effects of Methotrexate on Cardiovascular Risk in RA• Tate Johnson (Mikuls)
• Acute Pain Management in the Hospital Setting• Smitha Sagaram (Shiffermiller)
Ongoing Resident Projects• Role of Dynamin2 in NAFLD
• Laura Vance (Casey)
• How do Medical Students Learn Best?• Cory Rohlfsen (Cannella)
• Allergens in Eosinophilic Esophagitis• Annie Braseth (Poole)
• Quality of Life in Diabetes in Rural Patients• Meghan Combs (Eiland)
• Treatment of Perioperative Hyperglycemia• Matthew Day (Shiffermiller)
• Improving Care with Diabetic Foot Ulcers• Randy McCreery (Van Schooneveld)
• Quality of Care in Paracentesis• Brett Henderson, Molly Brittan (Shiffermiller, Smith)
• Genetic risk for Extra-articular RA• Lilli Mauer (Mikuls, England)
• Outcomes with Abnormal LFTs• Neil Bhogal (Olivera-Martinez)
Resident/Fellow Poster Session
• Tate Johnson won the award for Best Resident Poster
“Correlation of the Multi-Biomarker Disease Activity Score with Composite Rheumatoid Arthritis Disease Activity Measures: A Systematic Review and Meta-Analysis”
Internal Medicine Research:
• Resident Research Fair – Monday, August 20, 12-1 p.m., Private Dining Rooms
• Resident Research Interest Group (meets the first Wednesday of the month at noon)
• Next meeting Wednesday, Sept. 5:• “Research for the Internal Medicine Resident” (England)
• Upcoming meetings: • 10/3 and 12/5: “Basic Statistics” (Smith)
• 11/7: “Systematic Review and Meta-Analysis” (Michaud)
• Please accept or decline invitation for these
• Research Months
• One-month or three-month rotation
• Applications due early to mid-February
Resident Research Interest Group
• Research in Progress (RIP) –Peer and mentor feedback
• Visitor Presentations:• Basic Science Research• How to Responsibly Conduct Research• Research Ethics and Integrity• IRB Procedures• Research Resources at the Library
(citation managers, library search tools, finding experts, etc.)
• How to Choose a Mentor• Building Interpersonal, Professional
and Mentoring Skills• Statistics 101 • Statistical Design• Data Analysis
• First Wednesday of each month• Resident contacts: Brett Henderson, Kaitlyn Brittan, Tate
Johnson
• Systematic Review and Meta-Analysis• Submitting a Grant/Grantsmanship• Writing to Get Published• How to Make and Present a Great Poster• Clinical and Translational Research Design• Study Implementation and Management• Biostatistics• Quantitative Measurement• Patient Outcomes• Conducting Research• Biomedical Informatics• Cultural Competence• Scientific Writing
“Biostatistics”
“Biostatistics”
Center for Collaboration on Research Design and Analysis (CCORDA)
• Contacts: Fang Yu, PhD ([email protected]) or Lynnette Smith, PhD ([email protected])
• Supported by MOU with Department
• Support with stats, design, database and survey development, others…
• Statistical consulting class• Win-win for COPH students and research trainees
Funds for Meeting Travel & Presentation
1. Travel Award to support travel for presenting scholarly activity
– $2,000 per award
2. Development Award to support Quality Improvement projects
– Up to $3,000 per award
– Mentored projects
– Reviewed by IMRC and other faculty
3. External Sources
- Foundations (ASCO, ACR, AHA)
- NIH (e.g. F32)
Think BIG
For Example:
• Foundations / Trainee Grants & Travel Awards
• Large (national) datasets
Getting Started
• Attend the next Resident Research Interest Group meeting
• Talk to other residents
• Talk to me
• Find a mentor (Resident Research Fair, August 20th over noon hour)
• Be realistic…
• Think long-term…
Questions?
