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RESOLUTION O THF EXECUTIVE BOARE OD THF WHE O …

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世界銜生紐織執行委貝會决議 yu ^ ^ ^ ^ ^ RESOLUTION OF THE EXECUTIVE BOARD OF THE WHO RÉSOLUTION DU CONSEIL EXÉCUTIF DE L'OMS РЕЗОЛЮЦИЯ ИСПОЛНИТЕЛЬНОГО КОМИТЕТА ВОЗ RESOLUCION DEL CONSEJO EJECUTIVO DE LA OMS Eighty-seventh Session EB87.R6 Agenda items 5.2 and 6 21 January 1991 RESEARCH AND DEVELOPMENT IN THE FIELD OF CHILDREN'S VACCINES The Executive Board, Having considered the report of the Director-General on the programme for vaccine development; 1. THANKS the Director-General for his report; 1 2. RECOMMENDS to the Forty-fourth World Health Assembly the adoption of the following resolution: The Forty-fourth World Health Assembly, Noting the report of the Director-General on the programme for vaccine development; Appreciating the accomplishments of the programme for vaccine development during its first six years of existence in developing several candidate vaccines against viral or bacterial diseases and in promoting the establishment of new approaches for the design of single-dose slow release and oral vaccines, including tetanus vaccine Noting that new and improved vaccines against viral and bacterial diseases could save as many as six to eight million lives annually during the 1990s Considering that the objectives of the programme for vaccine development represent an essential component of the global effort made within the scope of the Children's Vaccine Initiative to improve means to immunize all children of the world; 1. ENDORSES the proposed objectives of the WHO/UNDP programme for vaccine development in relation to the global effort to develop improved and new essential vaccines against major childhood diseases, including: (1) improving access to immunization, concentrating on developing improved vaccines against childhood diseases that could simplify immunization schedules that would require only one or two doses that could be given earlier in life that could be combined in novel ways, reduce unit costs, bring down drop-out rates and be more heat-stable and efficient; Document EB87/6.
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Page 1: RESOLUTION O THF EXECUTIVE BOARE OD THF WHE O …

世 界 銜 生 紐 織 執 行 委 貝 會 决 議 y u ^ ^ ^ ^ ^

R E S O L U T I O N O F T H E E X E C U T I V E B O A R D O F T H E W H O

R É S O L U T I O N D U C O N S E I L E X É C U T I F D E L ' O M S

РЕЗОЛЮЦИЯ ИСПОЛНИТЕЛЬНОГО КОМИТЕТА ВОЗ

R E S O L U C I O N D E L C O N S E J O E J E C U T I V O D E L A O M S

E i g h t y - s e v e n t h S e s s i o n EB87.R6

A g e n d a items 5.2 a n d 6 21 J a n u a r y 1991

R E S E A R C H A N D D E V E L O P M E N T IN THE FIELD O F C H I L D R E N ' S V A C C I N E S

T h e E x e c u t i v e B o a r d ,

H a v i n g c o n s i d e r e d the r e p o r t of the D i r e c t o r - G e n e r a l o n the p r o g r a m m e for v a c c i n e

d e v e l o p m e n t ;

1 . T H A N K S the D i r e c t o r - G e n e r a l for h i s r e p o r t ; 1

2. R E C O M M E N D S to the F o r t y - f o u r t h W o r l d H e a l t h A s s e m b l y the a d o p t i o n of the f o l l o w i n g

r e s o l u t i o n :

The F o r t y - f o u r t h W o r l d H e a l t h A s s e m b l y ,

N o t i n g the r e p o r t of the D i r e c t o r - G e n e r a l o n the p r o g r a m m e for v a c c i n e

d e v e l o p m e n t ;

A p p r e c i a t i n g the a c c o m p l i s h m e n t s of the p r o g r a m m e for v a c c i n e d e v e l o p m e n t

d u r i n g its f i r s t six y e a r s of exi s t e n c e in d e v e l o p i n g s e v e r a l c a n d i d a t e v a c c i n e s

a g a i n s t v i r a l or b a c t e r i a l diseases and in p r o m o t i n g the e s t a b l i s h m e n t of n e w

ap p r o a c h e s for the d e s i g n of single-dose slow r e l e a s e a n d ora l v a c c i n e s , i n c l u d i n g

tetanus vaccine;

N o t i n g that n e w a n d i m p r o v e d v a c c i n e s a g a i n s t v i r a l a n d b a c t e r i a l d i s e a s e s

c o u l d save as m a n y as six to eigh t m i l l i o n lives a n n u a l l y d u r i n g the 1990s;

C o n s i d e r i n g that the ob j e c t i v e s of the p r o g r a m m e for v a c c i n e d e v e l o p m e n t

r e p r e s e n t a n e s s e n t i a l c o m p o n e n t of the gl o b a l e f f o r t m a d e w i t h i n the scope of the

Ch i l d r e n ' s V a c c i n e I n i t i a t i v e to improve m e a n s to immunize all c h i l d r e n of the

wo r l d ;

1. ENDORSES the p r o p o s e d o b j e c t i v e s of the W H O / U N D P p r o g r a m m e for v a c c i n e

d e v e l o p m e n t in re l a t i o n to the global e f f o r t to d e v e l o p i m p r o v e d a n d n e w e s s e n t i a l

v a c c i n e s a g a i n s t m a j o r c h i l d h o o d d i s e a s e s , including:

(1) i m p r o v i n g access to i m m u n i z a t i o n , c o n c e n t r a t i n g on d e v e l o p i n g i m p r o v e d

v a c c i n e s a g a i n s t c h i l d h o o d d i s e a s e s that c o u l d s i m p l i f y i m m u n i z a t i o n

schedules; that w o u l d require o n l y one or two doses; t h a t c o u l d b e g i v e n

e a r l i e r in life; t h a t c o u l d b e co m b i n e d in n o v e l w a y s , r e d u c e u n i t c o s t s ,

b r i n g d o w n d r o p - o u t r a t e s and be m o r e h e a t - s t a b l e a n d e f f i c i e n t ;

Document EB87/6.

Page 2: RESOLUTION O THF EXECUTIVE BOARE OD THF WHE O …

EB87 page

(2) s u p p o r t i n g the a c c e l e r a t i o n o f the d e v e l o p m e n t o f n e w v a c c i n e s a g a i n s t

b a c t e r i a l m e n i n g i t i d e s , a c u t e r e s p i r a t o r y i n f e c t i o n s , d i a r r h o e a l d i s e a s e s ,

v i r a l h e p a t i t i s , d e n g u e , t u b e r c u l o s i s a n d o t h e r c o m m u n i c a b l e diseases;

2 . U R G E S M e m b e r S t a t e s :

(1) to i n t e n s i f y e f f o r t s m a d e a t n a t i o n a l l e v e l to a c c e l e r a t e r e s e a r c h r e l a t e d

to v a c c i n e d e v e l o p m e n t ;

(2) to c o l l a b o r a t e in i n t e r n a t i o n a l i n i t i a t i v e s a i m e d a t the d e v e l o p m e n t of

n e w a n d i m p r o v e d v a c c i n e s a n d to p a r t i c i p a t e in the f i e l d a s s e s s m e n t o f

c a n d i d a t e vaccines;

3 . C A L L S O N b i l a t e r a l a n d m u l t i l a t e r a l d e v e l o p m e n t a g e n c i e s , n o n g o v e r n m e n t a l

o r g a n i z a t i o n s a n d f o u n d a t i o n s :

(1) to i n c r e a s e t h e i r s u p p o r t for v a c c i n e r e s e a r c h w i t h i n the s c o p e o f the

C h i l d r e n ' s V a c c i n e Initiative;

(2) to s u p p o r t a n d s t r e n g t h e n n a t i o n a l c o o r d i n a t i o n m e c h a n i s m s to p r o m o t e

v a c c i n e d e v e l o p m e n t ;

(3) to s u p p o r t the d e v e l o p m e n t o f i n t e r n a t i o n a l p a r t n e r s h i p s to s t r e n g t h e n

c o u n t r i e s ' c a p a b i l i t i e s for d e v e l o p i n g , p r o d u c i n g a n d a s s e s s i n g n e w v a c c i n e s

w i t h i n the s c o p e o f the C h i l d r e n ' s V a c c i n e Initiative;

4 . R E Q U E S T S the D i r e c t o r - G e n e r a l to e n s u r e the i m p l e m e n t a t i o n o f t h e s e o b j e c t i v e s

a n d t a r g e t s a n d W H O ' s m a x i m a l s u p p o r t to the C h i l d r e n ' s V a c c i n e I n i t i a t i v e b y :

(1) s t i m u l a t i n g r e s e a r c h o n n e w a n d i m p r o v e d v i r a l a n d b a c t e r i a l vaccines;

(2) c o o r d i n a t i n g i n t e r n a t i o n a l a n d n a t i o n a l e f f o r t s a i m e d a t the d e v e l o p m e n t ,

p r o d u c t i o n a n d d e l i v e r y of t h o s e v a c c i n e s ;

(3) i n t e n s i f y i n g W H O ' S c o l l a b o r a t i o n w i t h i n d u s t r y in o r d e r to a c c e l e r a t e

v a c c i n e r e s e a r c h a n d d e v e l o p m e n t a n d to e n s u r e t h a t n e w v a c c i n e s a r e a c c e s s i b l e

a n d a f f o r d a b l e for the p o p u l a t i o n s a f f e c t e d ;

(4) i n c r e a s i n g e f f o r t s to t r a i n s c i e n t i s t s f r o m d e v e l o p i n g c o u n t r i e s in a l l

a s p e c t s o f v a c c i n o l o g y , i n c l u d i n g b i o t e c h n o l o g y , i m m u n o l o g y , f i e l d trials a n d

q u a l i t y c o n t r o l , a n d p r o v i d i n g m o r e o p p o r t u n i t i e s for t h e s e s c i e n t i s t s to

p a r t i c i p a t e in v a c c i n e r e s e a r c h ;

(5) r e q u e s t i n g m u l t i l a t e r a l a n d b i l a t e r a l a g e n c i e s to p l a c e g r e a t e r e m p h a s i s

o n the p r o v i s i o n o f a s s i s t a n c e for v a c c i n e r e s e a r c h a n d v a c c i n e t r i a l s in

e n d e m i c countries;

(6) m o b i l i z i n g a d d i t i o n a l r e s o u r c e s for the p r o g r a m m e for v a c c i n e d e v e l o p m e n t

in c o l l a b o r a t i o n w i t h U N D P , the со-sponsoring a g e n c y , U N I C E F a n d o t h e r

i n t e r n a t i o n a l parties;

5 . R E Q U E S T S the D i r e c t o r - G e n e r a l to k e e p the E x e c u t i v e B o a r d a n d the W o r l d H e a l t h

A s s e m b l y i n f o r m e d o f the p r o g r e s s m a d e in i m p l e m e n t i n g this r e s o l u t i o n .

R 2

T h i r t e e n t h m e e t i n g , 21 J a n u a r y 1991

E B 8 7 / S R / 1 3


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