RESPIRATION AND RESPIRATION AND
GAS EXCHANGE
Key concepts� Types of respiration
� Cellular Respiration is the chemical breakdown of food substances to yield ATP. � Different organisms use different kinds of breathing mechanisms in order to transport oxygen
throughout their bodies.
� Evolutionary adaptations of gas exchange systems and respiration� Different plant adaptations in acquiring CO from the environment evolved: C3, C4, and CAM � Different plant adaptations in acquiring CO2 from the environment evolved: C3, C4, and CAM
pathways.� Structural adaptations of respiratory apparatus depend on the animal’s habitat. The three
most common respiratory organs are gills, tracheae, and lungs.� The respiratory system and circulatory system cooperate directly with each other.
� Mammalian respiration� The respiratory system is divided into the upper respiratory tract (nasal passages, mouth,
throat, larynx and trachea) and lower respiratory tract (bronchi and the lungs).� Air enters (inhalation) the respiratory system due to a pressure drop inside the lungs (negative
pressure).pressure).� Air exits (exhalation) the respiratory system due to an increase in pressure inside the lungs.� Breathing is regulated by control centers in the brain (medulla oblongata and pons)� Gases are transported via passive diffusion throughout the body.
� Respiratory diseases and their prevention� Respiratory disorders may be congenital or environmental.� Respiratory disorders can be prevented through a combination of proper diet and lifestyle
change.
Vocabulary words
� aerobic respiration
� air sacs
� alveolus
� anaerobic respiration
� emphysema
� epiglottis
� gas exchange
� gills
� pneumonia� pons� positive pressure breathing� residual volume� respiratory medium� anaerobic respiration
� asthma
� blood pH
� Bohr shift
� breathing
� bronchiole
� bronchus
� C3 pathway
� C4 pathway
� glottis
� glycolysis
� hemocyanin
� hemoglobin
� larynx (voicebox)
� lung Cancer
� lungs
� medulla oblongata
� myoglobin
� nasal cavity
� respiratory medium� respiratory pigments� respiratory surface� rib muscles� spiracle � surface tension� syrinx� thoracic cavity� tidal volume� trachea or windpipe� tracheae� tuberculosis� C4 pathway
� CAM pathway
� cell respiration
� countercurrent exchange
� cutaneous respiration
� diaphragm
� dissociation curve
� nasal cavity
� negative pressure breathing
� nose
� parabronchi
� partial pressure
� pharynx
� photosynthesis
� tuberculosis� ventilation � vital capacity� vocal cords of the larynx
Cellular Respiration- Transformation of chemical energy into ATP
- Overall Reaction: C6H12O6 +6O2 → 6CO2 +6H2O + 36 ATP
1 Glucose molecule 1 Glucose molecule (6C) from digestion
Glycolysis in the cytoplasm �
2 pyruvate molecules (3C)
2 ATPs2 ATPs
Aerobic Respiration in the mitochondria
Krebs Cycle (2 ATPs)
Electron Transport Chain
(32 ATPs)
� CO2+ H2O
Anaerobic Respiration in
the cytosol �
ethanol/lactic acid/CO2
NADH and FADH2 are
e- donors that enable the
formation of ATP
Photosynthesis
� Method of converting sun energy into chemical
6 CO2 + 6 H2O + light
energy →C6H12O6 + 6O2
energy into chemical energy usable by cells
� Light reactions
� Dark reactions/Calvin Cycle
Plant adaptations for
acquiring CO2 from the
environment
� C3 (most abundant)
� CO2 converted to a 3C sugar, 3-phosphoglycerate
� RuBisCO (Ribulose-1,5-bisphosphate � RuBisCO (Ribulose-1,5-bisphosphate
carboxylase/oxygenase) enzyme catalyzes carbon fixation
� prone to photorespiration, lessens efficiency of
food production during hot and dry days
� C4
� store CO2 in specialized compartments
� convert CO2 into a 4C compound, oxaloacetate
� converted into the 3C sugar and CO2 used in the C3 pathway/Calvin cyclepathway/Calvin cycle
� minimizes photorespiration and enhances sugar production
� CAM
� succulent plants
� f ix CO2 at night and store it as 4C organic acids
� minimizes water loss and enhances sugar production
Gas exchange supplies oxygen for
cellular respiration and removes CO2
� Gas exchange – uptake of O2 from environment and O2 from environment and discharge of CO2
� Mitochondria need O2 to produce more ATP, CO2 is the by-product
C6H12O6 + 6O2 � 6CO2 + 6H2O + 36 ATP
� Diffusion rate � α SA � large� α SA � large
� α 1/d2 � thin
� Moist so gases are dissolved first DIFFUSION
Respiratory surfaces and gas exchange
� Respiratory surface � Simple invertebrates
� Size of organism
� Habitat
� Metabolic demands
� Unicellular organisms
� Entire surface area for
diffusion
� Sponges, cnidarians,
flatworms, roundworms
� diffusion
diffusion
Respiratory surfaces and gas exchange
� More complex animals
� Thin, moist epithelium
Separates medium from � Separates medium from
capillaries
� Entire outer skin � small, long, thin organisms
� Specialized respiratory organs that are extensively
folded and branchedfolded and branched
Gills in aquatic animals
� Outfoldings of the body surface suspended in surface suspended in water
� Sea stars
� Segmented worms or polychaetes
� Molluscs and crustaceans
� Fishes� Fishes
� Young amphibians
� Total surface area is greater than the rest of the body
Water as a respiratory medium
� Surfaces are kept moist
� O2 concentrations in water
are low
Just keep swimming swimmingswimming!
are low
� Ventilation – increasing
flow of respiratory medium
over the surface
� Countercurrent exchange –
process in which two fluids
flow in opposite directions,
swimming!
flow in opposite directions,
maximizing transfer rates
� Why are gills impractical
for land animals?
Air as a respiratory medium
� Air has a higher
concentration of O2
� Tracheal system of insects –network of tubes that bring O2
to every cellconcentration of O2
� O2 and CO2 diffuse
much faster in the air
� less ventilation
� Difficulty of keeping
surface moist
to every cell
Spiraclessurface moist
� Solution: respiratory
infolding inside the
body
Spiracles
Lungs
� Heavily vascularized
invaginations of the body invaginations of the body
surface restricted to one
location
� Found in spiders, terrestrial
snails, vertebrates
� Amphibians supplement
lung breathing with skinlung breathing with skin
� Turtles supplement lung
breathing with moist
surfaces in mouth and anus
Mammalian
respiration
Lung ventilation through breathing
� Positive pressure
breathing in frogs
� “Gulping in” air
� Negative pressure breathing in reptiles and mammals
� Rib muscles and diaphragm change lung volume and pressure� “Gulping in” air and pressure
Lung volumes
� Factors
� Sex
� Height
� Tidal volume
� Volume of air inhaled and
exhaled with each breath
� Vital capacity
� Maximum volume inhaled � Height
� Smoking
� Physical activity
� Altitude
� Maximum volume inhaled and exhaled during forced breathing
� Residual volume
� Air left in alveoli after forced
exhalation
Avian breathing
•Air sacs - bellows to keep air flowing through the lungsthrough the lungs•Syrinx – vocal organ of birds
Control
centers in
the brain
regulate regulate
breathing
Gases
diffuse down
pressure
gradients
concentrationand
pressuredrives the
movement of gases into
and out of blood
Respiratory
pigments
� O2 transport
� Low solubility of O2 in � Low solubility of O2 in
H2O
� Respiratory pigments
are proteins with metal
atoms
� Hemoglobin – Fe
� Hemocyanin – Cu� Hemocyanin – Cu
� Allow reversible binding of O2
� Drop in pH results in a lowered affinity of hemoglobin for O2
Respiratory
pigments
� CO2 transport
� 7% in plasma
� 23% bound to
hemoglobin
� 70% as HCO3-� 70% as HCO3
� ***buffer
Fetal hemoglobin
HbF has greater affinity to O2 than Hb
� low O2% by time blood reaches placenta
� fetal Hb must be able to bind O2 with greater � fetal Hb must be able to bind O2 with greater attraction than maternal Hb
Deep-diving mammals � Seals, whales, dolphins are
capable of long underwater
dives
� Weddell seal � 5% O2 in lungs, 70% in bloodlungs, 70% in blood
� Huge spleen stores huge
volumes of blood
� Large concentrations of
myoglobin in muscles
� Heart rate and O2 � Heart rate and O2
consumption rate decrease
� Blood is redirected from
muscles to brain, spinal
cord, and eyes