20
Volume-5, Issue-1
Volume-5, Issue-1
Salmeterol ( as Xinafoate) BP & Fluticasone Propionate BP
HFA Inhaler 25/125, 25/250
Rotacap 50/100, 50/250, 50/500
In Asthma, COPD & ACOS
Doxophylline INN 200 mg & 400 mg Tablet
DophylinTM
2-4
5-7
8-10
11-13
14-16
Organizing pneumonia co-existing with carcinoid tumour: complete resolution with bronchoscopic tumour resection
Persistent focal pulmonary opacity elucidated by transbronchial cryobiopsy: a case forlarger biopsies
E�ectiveness of pulmonary vasodilators on pulmonary hypertension associated with POEMS syndrome
Unusual presentation of Castleman’s disease mimicking lung cancer
Pleuritis with pleural e�usion due to a Bacillus megaterium infection
AbstractOrganizing pneumonia is a well-known clinical entity resulting in response to noxious stimuli causing lung injury. It is known to occur with infectious disease processes, neoplasms, post lung surgery or radiation therapy and when idiopathic, is called cryptogenic organizing pneumonia. We present an unusual case of a 48-year-old woman who presented with chronic cough and progressive dyspnoea while being on macrolide therapy for Lyme disease. Comput-erized tomography of chest demonstrated a well-circumscribed nodule in the lingula and bilateral central ground glass opacities. Transbronchial biopsies were consistent with carcinoid tumour in the lingula and organizing pneumonia in bilateral lung fields. Bronchoscopic relief of obstruction was performed by mechanical debulking of the tumour, with subsequent complete resolution of bilateral opacities, consistent with resolution of organizing pneumonia without the need for steroid therapy.
KeywordsCarcinoid tumour, organizing pneumonia.
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
AbstractPersistent pulmonary opacities associated with respiratory symptoms that progress despite medical treatment present a diagnostic dilemma for pulmonologists. We describe the case of a 37-year-old woman presenting with progressive fatigue, shortness of breath, and weight loss over six months with a progressively worsening right basilar infiltrate on chest imaging in spite of antibacterial therapy. Transbronchial cryobiopsy was used to establish the diagnosis after a bronchoscopy with traditional forceps biopsies was non-diagnostic. This case demonstrates the value of cryobiopsy as a secondline strategy for pulmonary infiltrates when aetiology remains unclear after less invasive testing.
KeywordsBlastomyces dermatitidis, blastomycosis, pulmonary infiltrates, pulmonary opacity, transbronchial cryobiopsy.
5
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
Keywordspolyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes syn- drome, pulmonary hypertension (PH), macitentan, sildenafil, vascular endothelial growth factor (VEGF).
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
AbstractPolyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a rare plasma cell disease. Patients with POEMS syndrome are considered to be at a high risk of developing pulmonary hypertension (PH). We report a 51-year-old woman diagnosed with PH associated with POEMS syndrome. She was started on dexamethasone and thalidomide. Although, the plasma vascular endothelial growth factor (VEGF) level decreased, systolic pulmonary artery pressure (sPAP) remained high. Auto-peripheral blood stem cell transplantation improved the plasma VEGF and sPAP levels. Four years later, she presented with dyspnoea on exertion, and elevated plasma VEGF and sPAP levels. Subsequently, on administering sildenafil and macitentan, the plasma VEGF and PH levels improved. Pulmonary vasodilators can be considered when PH remains after treatment of POEMS syndrome.
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
KeywordsCastleman’s disease, lymphadenopathy, peribronchovascular interstitial thickening.
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
Abstract
Castleman’s disease (CD) is an uncommon lymphoproliferative disorder characterized as either unicentric or multi-centric presentation based on the involving sites. The most frequent presentation of CD is a solitary mediastinal mass. We reported a patient with a history of heavy smoking with particular image features of CD, which presented as medi-astinal lymphadenopathy and peribronchovascular interstitial thickening mimicking lung cancer or sarcoidosis initially
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
KeywordsBacillus megaterium infection, pleural effusion, pleuritic.
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4 14
AbstractPleural effusions may be related to pleuro-pulmonary or systemic disorders, including malignancy. Thoracentesis and thoracoscopy may be useful to diagnosis. In some cases, the diagnosis may be difficult and uncommon. We report the case of a hospitalized male for a pleuritis, with pleural effusion caused by a Bacillus megaterium infection, a Gram-positive, aerobic, spore-forming, and rod-shaped bacterium. To our knowledge, our case report is the first evidence of pleuritis due to B. megaterium. In the literature, up to now, B. megaterium infection has only been reported as involv-ing the eye, skin, and brain.
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4 15
The Asian Pacific Society of Respirology
2019 | Vol.7 | Iss.4
