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21 - 23 April 2015 Djibouti City, Djibouti “RVF: NEW OPTIONS FOR TRADE, PREVENTION AND CONTROL” INTER-REGIONAL CONFERENCE MIDDLE EAST & HORN OF AFRICA OIE Sub-Regional Representation for Eastern Africa FAO Emergency Centre for TADs (ECTAD) Eastern Africa Nairobi, Kenya
Transcript

21 - 23 April 2015Djibouti City, Djibouti

“RVF: NEW OPTIONS FOR TRADE, PREVENTION

AND CONTROL”

INTER-REGIONAL CONFERENCE MIDDLE EAST & HORN OF AFRICA

INT

ER-R

EGIO

NAL CO

NFER

ENCE M

IDD

LE EAST

& H

ORN

OF A

FRICA

“RVF : N

EW O

PTIO

NS FO

R T

RA

DE, PR

EVEN

TIO

N A

ND

CON

TRO

L”

OIE Sub-Regional Representation for Eastern AfricaFAO Emergency Centre for TADs (ECTAD) Eastern Africa

Nairobi, Kenya

Viale de terme di Caracalla, 00153 Rome, ITALYEmail: [email protected] | http://www.fao.org

12, rue de Prony, 75017 Paris, FRANCEEmail: [email protected] | http://www.oie.int

INTEMID

“R

OIE Su

FAO Em

ER-REDLE E

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ub-Regio

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REEGIONEAST

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Djibou

onal Rep

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presenta

e for TAD

irobi Ke

August 201

RT CONRN O

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Djibouti

ation for

Ds (ECT

enya

15

FEREF AFR

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Eastern

AD) Eas

NCE RICA

de,

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st Africa

World Organisation for Animal Health OIE 12, rue de Prony 75017 P A R I S FRANCE [email protected] www.oie.int OIE Regional Representation for the Middle East 4th floor, Min. of Agriculture, Al Kaake Bldg, Jnah B E I R U T LEBANON + 961 1 843 467 [email protected] www.rr-middleeast.oie.int OIE Regional Representation for Africa Parc de Sotuba Park P.o.box 2954 B A M A K O MALI + 223 20 24 60 53 [email protected] www.rr-africa.oie.int Sub-Regional Representation for Eastern Africa 4th floor, Taj Tower, Upper Hill Road, Upper Hill P.O. Box 19687 00202 N A I R O B I KENYA + 254 20 271 3461 [email protected] www.rr-africa.oie.int

Food and Agriculture Organisation FAO Viale de terme di Caracalla 00153 R O M E ITALY [email protected] www.fao.org FAO Regional Office for the Near East and North Africa. 11, Al-Eslah Al-Zerai Street, Dokki C A I R O EGYPT + 202 3331 6000 - 6007 [email protected] www.fao.org/neareast/en/ FAO Regional Office for Africa 2, Gamel Abdul Nasser Road P.O. Box GP 1628 A C C R A GHANA +233 (0) 302 610930 [email protected] www.fao.org/africa/en/ FAO ECTAD Office for Eastern Africa United Nations Office Nairobi (UNON) Block P, Level 3, United Nations Complex UN Avenue, Gigiri N A I R O B I KENYA +254 20 76 25928 [email protected] www.fao-ectad-nairobi.org

- 4 -

ACRONYMS

AHC Animal Health Certification ARC Agricultural Research Council [South Africa] ARIS Animal Resource Information System [AU-IBAR] ASF African Swine Fever AU African Union AUC AU Commission BSL Bio-Safety Level C-AHRN Chief Animal Health Regional Network CAHW Community-based Animal Health Workers CBPP Contagious Bovine Pleuro-Pneumonia CCPP Contagious Caprine Pleuro-Pneumonia CDC Centres for Disease Control and Prevention [US] CIRAD Centre de Coopération Internationale en Recherche Agronomique pour le Développement [France] COMESA Common Market for Eastern and Southern Africa CP Communication Plan CVI Central Veterinary Institute [Netherlands] CVL Central Veterinary Laboratory [Yemen] CVO Chief Veterinary Officer DAFF Department of Agriculture, Forestry and Fisheries [DAFF] DIVA Differentiating infected from vaccinated animals DNA Deoxyribo-Nucleic Acid DREA Department of Rural Economy and Agriculture [AUC] DVS Department of Veterinary Services EA East(ern) Africa EAREN Eastern Africa Regional Epidemiology Network EARLN Eastern Africa Regional Laboratory Network EC European Commission ECTAD Emergency Centre for Trans-boundary Animal Diseases [FAO] ELISA Enzyme Linked Immuno-Sorbent Assay ENSO El Niño Southern Oscillation EU European Union EWS Early Warning System FAO Food and Agriculture Organisation [UN] FMD Foot and Mouth Disease GALVMed Global Alliance for Livestock Veterinary Medicines GCC Gulf Cooperation Council GDP Gross Domestic Product GF-TAD Global Framework for the progressive control of Trans-boundary Animal Disease GMO Genetically modified organism(s) HoA Horn of Africa IAEA International Atomic Energy Agency [UN] IBAR Interafrican Bureau for Animal Resources [AU] ICPALD IGAD Centre for Pastoral Areas and Livestock Development IGAD Inter-Governmental Authority for Development IHR International Health Regulations [WHO, 2005] ILRI International Livestock Research Institute [Kenya] ILTC Inter-Laboratory Test Comparison(s) KEMRI Kenya Medical Research Institute KSA Kingdom of Saudi Arabia LIDESA Livestock Development Strategy for Africa [DREA] LITS Livestock Identification and Traceability System(s) MCDA Multi-Criteria Decision Analysis MoA Ministry of Agriculture MoH Ministry of Health MS Member State(s)

- 5 -

NASA National Aeronautics and Space Administration [USA] ND Newcastle Diseases NDV ND Virus NOAA National Oceanic and Atmospheric Administration OBP Onderstepoort Biological Products [South Africa] OIE World Organisation for Animal Health OVI Onderstepoort Veterinary Institute [ARC] PAN-SPSO Participation of African Nations in SPS Standards-setting Organisations [AU-IBAR] PANVAC Pan-African Veterinary Vaccine Centre [AU] PCR Polymerase Chain Reaction PPR Peste de petits ruminants PVS Performance of Veterinary Services [OIE] REC Regional Economic Community REMESA Réseau Méditerranéen de Santé Animale RNA Ribo-Nucleic Acid RSC Regional Steering Committee [GF-TAD] Rt-PCR Reverse Transcriptase PCR RVF Rift Valley Fever RVFV RVF Virus SMP Standard Methods and Procedures SMP-AH Standard Methods and Procedures in Animal Health [AU-IBAR] SNT Serum Neutralisation Test SOP Standard Operating Procedure SPS [Agreement on the application of] Sanitary and Phytosantory Standards [WTO] STSD Surveillance of Trade-Sensitive Diseases [AU-IBAR] TAD Trans-boundary Animal Disease(s) UAE United Arab Emirates UK United Kingdom UNDP United Nations Development Programme US United States USAID United States Agency for International Development USD United States Dollar VETGOV Strengthening Veterinary Governance in Africa [AU-IBAR] VNT Virus Neutralisation Test WHO World Health Organisation [UN] WTO World Trade Organisation

- 6 -

This report can be downloaded from www.rr-africa.oie.int/docspdf/en/2015/RVF/Report.pdf ACKNOWLEDGMENTS This report was prepared and edited by Susanne Munstermann, Bouna Diop, Gregorio Torres and Patrick Bastiaensen. The OIE and the FAO gratefully acknowledge the contributions of Austine Bitek, Pierre Formenty, Stephane de la Rocque, James Wabacha and Samuel Wakhusama, as well as the staff of the OIE Representations for Eastern Africa and for the Middle East, who helped organise this meeting. DISCLAIMER All OIE (World Organisation for Animal Health) publications are protected by international copyright law. Extracts may be copied, reproduced, translated, adapted or published in journals, documents, books, electronic media and any medium destined for the public, for information, educational or commercial purposes, provided prior written permission has been granted by the OIE. The designations and denominations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the OIE concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers and boundaries. The views expressed in signed articles are solely the responsibility of the authors. The mention of specific companies or products of manufacturers, whether or not these have been patented, does not imply that these have been endorsed or recommended by the OIE in preference to others of a similar nature that are not mentioned. The wording Member (of the OIE) refers to OIE Member Countries and Territories. All weight units expressed in tonnes are metric tons. All distance and surface area units are expressed in metric units (km and km²) All pictures courtesy of Patrick Bastiaensen (2015) unless mentioned otherwise. © OIE (World Organisation for Animal Health), 2015 12, rue de Prony, 75017 Paris, France

“RVF :

Under tcontrol and me23rd, 2of the R

The ConincludinKuwait, Syria, T

The conLivestocprofile gH.E. Huof the IMoussathe FAOMarkos Ghazi YDeputy represenPathoge

THE MI

NEW OPT

the auspices of Trans-bou

edical profess015 to reass

Red Sea : “ne

nference wasng Bahrein,

Lebanon, Oanzania and

nference wasck, Water anguests were ussein Saïd, Inter-Governm, the FAO RO Regional RTibbo, the

Yehia, the DDirector o

nted by Dr. Pens Team in G

DDLE EAS

IONS FOR

of the FAO undary Animsionals and sess the situaew options fo

s attended byComoros,

man, Qatar, Uganda.

officially opnd Fisheries,

the Somali the Director mental Auth

Resident RepRepresentativOIE Region

Director of Aof AU-PANVPierre FormeGeneva.

- 7 -

T AND TH

TRADE, P

PREFACE

& OIE Globamal Diseases

scientists mation of Rift or trade, prev

y governmenDjibouti, EgSaudi Arabia

pened by theH.E. MohamMinister of of the Agric

hority on Devpresentative, ve for the Nal Represen

AU-IBAR, PrVAC, Dr. Centy from the

E HORN O

REVENTIO

E

bal Framewors (GF-TADs), met in Djibout Valley Fevervention and c

t representatgypt, Ethiopa, Somalia, S

Djibouti Mimed Ahmed Livestock,

culture and Evelopment (IDr. Emman

Near East anntative for throf. Ahmed harles Bodje WHO Emer

F AFRICA

ON AND CO

rk for the prosome 70 ve

uti from Aprr (RVF) on bocontrol”.

tives of 18 cpia, Jordan, South Sudan

nister of AgrAwaleh. Oth

Forestry andEnvironment GAD), M. Muelle Guernend North Afrhe Middle EEl-Sawalhy o. The WHrging and Da

ONTROL”

ogressive eterinary ril 21 to oth sides

countries Kenya,

, Sudan,

riculture, her high

d Range, Division

Mohamed e-Bleich, rica, Dr.

East, Dr. and the HO was angerous

- 8 -

The meeting was organised around 5 formal thematic sessions, interspersed with two working group sessions and a visit to the Djibouti Livestock Export Quarantine Facility, operated by the PRIMA International Company. The thematic sessions were

• Session 1 : setting the scene

• Session 2 : challenges to disease control

• Session 3 : trade issues

• Session 4 : prevention, biothreat and early warning

• Session 5 : regional coordination

The experts and participants, through formal presentations, case studies and mock negotiations, as well as through the visit of the quarantine station, were given the opportunity to exchange views on the current spread of RVF infection in Western, Southern, Eastern Africa, the Horn of Africa and the Middle-East, the new developments regarding vaccines and diagnostics, but also the delays in the registration, at national levels, of not-so-new vaccines such as the "Clone 13" vaccine, the consequences of the revised Code Chapter on RVF for international trade in live animals, issues of certification and transparency, forecasting and disease preparedness, as well as regional initiatives in support of Rift Valley fever control at regional (IGAD, African Union) and international (GF-TADs).

Major discussions evolved around new vaccines with the potential to reconcile prophylaxis with the maintenance of trade (DIVA vaccines : differentiating infected from vaccinated animals), the escalating costs and dwindling availability of commercial diagnostic kits, the imminent threat of a new epizootic phase in countries such as South Sudan, Kenya, Tanzania, and others, based on the fact that 2015 is year 8 after the last outbreaks that occurred in the region and that the ENSO (El-Nino Southern Oscillation) prediction model shows a consistent increase in chances of climate abnormalities occurring towards the end of this year (2015). Participants recommended making use of all available information and tools, including the recently updated decision support framework for Rift Valley fever and the WHO-OIE Operational Framework on Good Governance of human and animal health services.

Inputs into the meeting were provided by the African Union (AU-IBAR and AU-PANVAC) and the Inter-Governmental Authority on Development (IGAD), the regional economic community for the Horn of Africa, along with speakers from international organisations such as FAO, OIE, WHO and ILRI, and private and public stakeholders in research and trade, such as CDC-Kenya (Kenya), CVI Lelystad (Netherlands), Deltamune (South Africa), GALVmed (UK), KEMRI (Kenya), OBP (South Africa), ARC-OVI (South Africa), MCI (Morocco) and NASA (US).

The organisers were grateful for the financial support provided by the Governments of Great Britain (UK) and the United States (US) through the OIE World Animal Health and Welfare Fund and the AU-IBAR Standard Methods and Procedures in Animal Health project (SMP-AH) respectively. The considerable support provided by PRIMA International C° was equally acknowledged

More information : http://www.rr-africa.oie.int/en/news/20150422.html

- 9 -

TABLE OF CONTENTS

Preface page 7 Opening ceremony 11 Welcoming address by the OIE Regional Representative for the Middle East 13 Welcoming address by the OIE Sub - Regional Representative for Eastern Africa 15 Welcoming address by the Representative of FAO (Djibouti) 17 Opening address by the Representative of AU – IBAR 18 Opening address by the Representative of AU – PANVAC 20 Opening address by the Representative of IGAD 22 Opening address by the Djibouti Minister of Agriculture, Livestock, Water and Fisheries 24 Session 1 : Setting the scene 27 Session 2 : Challenges to disease control 35 Session 3 : Trade issues 47 Session 4 : Prevention, biological threats and early warning 53 Session 5 : Regional coordination 61 Session : Poster session 71 Conclusions 77 Annexes 83 Conference programme 85 Report of the working group session 1 88 Report of the working group session 2 95 List of participants 104 Useful websites 115 RVF chapter of the OIE Terrestrial Code (2014) 116

- 10 -

- 11 -

Session 0 Opening Session

- 12 -

RepresRegionOIE Beirut,

of devneeded Also tdevelohuge eWideswhich Ladies The mthe Howorksh RVF iscause biowea Trade socioefarmerillegal contamwould

WELCO

sentative al Represent

Lebanon

veloping lived for povert

the infectiopment of lieconomic lopread of anconstitute a

s and gentle

meeting aimsHorn of Africhop held in

s a vector bosevere and

apon. Contr

within aneconomic ars (in Sudan

trade betminating analso reduce

OMING AD

tation for the

estock and ty alleviation

ous animaivestock husosses causednimal diseasa barrier to emen,

s to improveca (HoA), bKenya (Mom

orne zoonotd fatal diseol of RVF fo

nd betweennd culturaln, South Sutween thesenimals and e the likelih

DRESS BYFOR T

e Middle East

Itw

PMFDais

Tii

livestock pn and comb

al diseases sbandry andd by their spses means the implem

e RVF contrbuilding on mbasa, 201

ic viral disease in humocuses on co

n the HoAl reasons audan, Somae regions humans. A ood of illeg

- 13 -

THE OIE RTHE MIDDL

Ghazi Yehia

t

have the pthe Rift Vaworkshop.

Permit me tMinister oFisheries foDjibouti, anall the officn Djibouti wseminar.

The animamportant anternationa

production. bat against h

are the d productiopread and ta high cost

mentation of

rol and to f the activit

12).

ease transmmans. RVF ontrolling in

A and theand to maalia, Djiboutcarries a spractical s

al trade.

REGIONAL LE EAST

ia

pleasure to walley fever

to start by ef Agricultor acceptin

nd also to Dcials and tewho contrib

l resourcess substanti

al communiNowadays,

hunger.

main souron due to thhe negativet of treatme country’s n

acilitate safties identifi

itted betweis considerenfections at

e Arabian intain the ti, Ethiopia significant solution to t

REPRESEN

welcome yo(RVF) follow

expressing oure, Livesng to holdDr Ibrahim Meam of the uted to the

s become al source oty has the new food

ce of riskhe numerou impact on ent and bignational dev

fe legal traded by the

en livestocked by manythe animal

Peninsula livelihoods and Kenyarisk for sp

trade betwe

NTATIVE

ou to the opow-up inter-

our gratitudstock, Watd this semMoussa CheVeterinary organisatio

increasingof food, so

common oresources a

ks threatens zoonoses the public

g loss of provelopment p

de in livestoGlobal Par

k and peoply to be a p source.

is importof poorer

a). Unregulapreading Reen the two

ening of -regional

de to the ter and minar in eikh and Services

on of the

ly more that the

objective are most

ing the and the health. oduction plans.

ock from rtnership

e; it can potential

tant for African

ated and RVF and o regions

- 14 -

To facilitate safe legal trade, the OIE has updated its international trade standards in the OIE Terrestrial Animal Health Code to account for the specific epidemiology of RVF and to facilitate trade in areas where infections are present. Current RVF vaccination strategies, although vaccines are much improved from previous versions, do require further refinement to properly implement the newly adopted OIE Standards. The meeting will focus on practical implementation of the RVF Chapter of the OIE’s Terrestrial Animal Health Code and will bring together key stakeholders from the public and private sector (trading partners and vaccine manufacturers) to enhance dialogue between the public and private sector with the aim of enhancing trust to implement the OIE standards. Furthermore the workshop should provide an update on early warning systems and their prediction capacities of high risk periods for disease occurrence. Ladies and Gentlemen, Today’s meeting is very important and we are most confident that you will all join efforts for collaboration and coordination. I wish you all success and enjoyable stay in this welcoming city of Djibouti.

ProgramSub-ReOIE Nairob

Ladiesthe plein 201is emba thrivof the This cthe diexpectColleag On OIEstandavirus (humanattackshow imRed Se ColleagAfrica the sp

WELCO

mme Officer egional Repre

i, Kenya

s and gentleeasure to co12. The locablematic of ving businesinter-epizoo

conference isease in tht a new epgues from F

E side, impoards and gu(and their n and anims in Garissa

mportant it ea, without

gues, I am that are cueakers from

OMING AD

esentation fo

emen, fromo-organise, ation chosethe livestocss, dynamicotic periods

is also timehis region tpisode in aFAO and NA

ortant progruidelines thaproducts),

mal populata in Kenya is to maintaforgetting t

particularlyurrently, or

m North Afric

DRESS BYFOR E

Pat

or East Africa

I mRewhsurunstrhe CotheMiMrimmaRV

a personali.e. Bloemfon for this th

ck trade thatc, innovatives that charac

ely from a hook place tfew month

ASA will talk

ress has beeat are intendespite the

tions in thehave shownain trade flothe importan

pleased to have been ca and Sout

- 15 -

THE OIE REASTERN A

atrick Bastiae

a and the Hor

must start bepresentativhom I reprergery and ddertake an

rongly regrehad worke

onference. I e Republicnister of Agr Mohamed portant intade in tradeVF.

l point of vontein, Souhird conferet takes place and unifycterize this

historical pothere nearlyhs. The opk about this

en made in nded to facie circulatioe importingn how politiows for the nce of relig

have in ourin the pastthern Africa

REGIONAL AFRICA

ensen

rn of Africa

by apologisie for Easteesent here doctors havny air travets not beined vigorousmust also w of Djibougriculture, LAhmed Aw

ter-regional e methodolo

iew, this is uth Africa, ience is obvice between ing, but whRVF.

oint of viewy ten years

perative wors.

normative tilitate traden of the vi

g countries.ically volatiwell-being ious calend

r midst reprt, heavily afa. Welcome!

REPRESEN

ng for the aern Africa, today. He

ve recommevel until fng here withly for the owarmly thanuti, represeLivestock, Wwaleh, for ag

conferenceogies, preven

the third cn 2009 andously no cothe HoA an

hich is cond

w. Indeed, ts ago, whicrd now sho

terms with t in animalsirus, but w The war le the regioof people oars.

resentatives ffected by t!

NTATIVE

absence of Dr Walter is recoveriended thatfurther noth us, knoworganisationnk the authoented here Water and Fgreeing to he on the ntion and c

conference d Mombasaoincidence. nd the Middducted by th

the last epish mean we

ould be "vig

the approvas susceptibl

without endain Yemen

on still remaon both side

s from other this virus. I

the OIE Masiga, ng after he not ice. He

wing that n of this orities of

by the isheries, host this progress ontrol of

I’ve had , Kenya, Djibouti le East : he grace

sodes of e should gilance".

al of new le to the angering and the ains and es of the

parts of refer to

- 16 -

To conclude, I would like to thank the numerous institutions and programmes which have provided financial support to the conference, to begin with our FAO friends with whom we work within the framework of the Global Framework for the progressive control of Trans-boundary Animal Disease (GF-TADs) Agreement. I also want to thank the African Union, through the Inter-African Bureau for Animal Resources, represented here by its Director, Prof. El-Sawalhy and the Intergovernmental Authority on Development, IGAD through the Centre for Pastoral Areas and Livestock Development, for the financial support which enabled the travel of many representatives of the HoA and East Africa. Finally, we are extremely grateful for the support of PRIMA INTERNATIONAL COMPANY which facilitated the travel of many representatives from the Gulf countries and the Middle East and invites us to visit the Animal Quarantine Centre of Djibouti on Thursday. Thank you all, thank you also to those private companies and institutions that have self-funded the travel of their representatives. Also thank you to the United Kingdom and the United States of America who have financially supported the previously mentioned programmes and institutions, which enables us to meet here in Djibouti in large numbers. I wish you all a great conference and I thank you for your kind attention.

WE

ResideDjiboutFAO Djibout

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ELCOMING

nt Representti and IGAD

ti, Djibouti

ther partnerin March 2

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continues toork (REMESm for RVF. Fses plans to

llaboration sis (MCDA) actors in Tae European t will impro

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e conclude Minister, foe thanks arations and

ADDRESS

tative

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o pay attenSA), FAO aFrom this yfocus on th

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netic modut will enabl

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my remarkor all the aalso go to a pleasant

BY THE FA

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ss the RVF.ng with the is currently

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on and invoo RVF data

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ks by thankiassistance p

the OIE astay in Djib

- 17 -

AO REPRES

anuelle Guern

s with greatDr. Grazianoe occasion erregional Cuntries of thnk the OIEthis meetingeting. The Frticipation adquarters, d the Near CTAD) Regio

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nce of RVF.

thin the fr conductedcan also ci

olving 17 pand studies

developed ik epidemiolo

ase for the use loss of ontinue to suH and STSDons with otniversities t

ing the Govprovided in and all of bouti. Thank

SENTATIVE

ne-Bleich

t pleasure to da Silva,

at the Conference he HoA and Director-Gg and for hFAO is fully

of collethe FAO ReEast and thonal Unit fo

n Djibouti malready orgayou of the wte of vaccin

within the establishme

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ramework o on the idenite the V-Mpartners, uns for better

n collaboratogical and g

countries oflife, but alsupport the e projects. Aher internato provide t

vernment ofconductingyou prese

k you for you

E TO DJIBO

that I take tFAO Directoopening

on RVF, br the Middleeneral for taving labell

y on board aeagues fregional Offihe Emergenr Eastern Af

marks anothanised by thworkshop ornes against

Mediterranent of a re8 project on

of the Multntification aERGE resea

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f the IGAD ro because oefforts undeAs a technicational and he necessar

Djibouti ang our missient here. I ur kind atte

OUTI AND I

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ncy Centre ffrica.

er phase in he OIE, FArganised byRVF and di

nean Animaegional survn vector-tran

lti-Criteria Dand classificarch project coordination.

he Swiss Insa.

region becaof its impacertaken by Acal agency,

regional tery assistanc

nd particulaon to Djibo wish you

ention.

GAD

n behalf to mark of the

ether the me first nitiative

GF-TADs d by the

Rome th Africa for TADs

a series AO, ILRI y FAO in agnostic

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Decision cation of t funded on. This

stitute of

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fruitful

DirectoInter-afAU Nairob

The AfOffice (AUC). utilisatand pro As youresourc2012 e35% osupporlivestocagricul Unfortuchallenregionaamong livestoc Disting AnimallivestocFurtherdisease TADs aTADs Rtrade precurreSomali2002.

OPE

or frican Burea

i, Kenya

frican Union of the DeparThe manda

tion of animaosperity of th

u all know, tces that repreestimate, IGAof Africa’s sts the livelihck contributetural GDP in

unately, the nges includinal level to cothers. Thes

ck sector in t

guished guest

l diseases, esck sector in rmore, the rees.

are the main RVF is one operformance ent livestock a alone lost

ENING ADD

u for Animal

Inter-Africartment of Ruate of AU-IBal resources the people in t

the countrieesent the higAD Member

small ruminahoods, housees significan the region.

performancng drought, coordinate ase constraintthe region in

ts, ladies and

specially thethe region

egion suffers

causes of saof the serious

of the livesimport banan income o

DRESS BY T

Ah

Resources

I have Commisto AfriConfere I also tConferemeeting I must MinistryDirectortirelesssuccess Distingu

an Bureau foural Economy BAR is to suto enhance nthe Member

es in Easternghest proportStates posse

ants populatehold food sently to the G

e of the livenvironmen

nd harmonizts are major order to con

d gentlemen,

e transboundand ten out from a mass

anitary restris diseases bestock sectorns by the Mof USD 435

- 18 -

THE REPRE

hmed El-Saw

the honour ssion and onca and to

ence on Rift V

take this oppence and fog.

also pay triby of Agricultrate of Lively and puttis of this Conf

uished guest

or Animal Rey and Agricultupport and cnutrition andStates of the

n Africa andtion of livestess 45% of Aion. As a reecurity and nGDPs of mo

vestock sectontal degradatze disease shindrances f

ntribute to im

,

dary animal d of the fiftesive burden o

ictions to liveecause of itsr in the Reg

Middle East cMillion due

ESENTATIV

walhy

to express, n my own beh

Djibouti foValley Fever.

portunity to tor inviting

ute to the Goture, Livestocestock and ing in placeference.

ts, ladies and

esource (AU-lture (DREA) coordinate t food securite AU.

d the HoA aock populatiAfrica’s cattesult of sucnutrition of m

ost countries

or in the retion, conflicsurveillance for the full e

mproved liveli

diseases (TADeen known Tof other ende

estock expors impact on gion. RVF hacountries anto the impo

VE OF AU -

on behalf ohalf, our pleaor this imp

thank the OIAU-IBAR to

overnment ofck, Water anVeterinary S

e excellent a

d gentlemen,

-IBAR) is a of the Africahe sustainabty and contri

are endowed ons in Africale, 71.4% ofh enormous millions of c

accounting

egion is hamt, low capaand control xploitation ohoods.

Ds), lower thADs are preemic as well

t trade in thpublic and s been the d accordingrt bans that

IBAR

of the Africaasure to welcportant Inter

IE for organio participate

f Djibouti thrnd Fisheries,Services, for arrangements

specialised tan Union Comble developmbute to the w

with huge a. According f Africa’s ca

s resources, citizens. Furt

on average

mpered by ncity at natioof animal

of the potent

e performanevalent in thas emerging

e Region. Amlivestock hecause of de

g to some elasted from

an Union come you r-regional

izing this e in the

rough the and the working

s for the

technical mmission ment and wellbeing

livestock to FAO’s

mels and livestock

thermore, 57% of

numerous onal and diseases, ial of the

ce of the e region.

g zoonotic

mong the alth, and

evastating stimates, 1998 to

- 19 -

Ladies and gentlemen, Recognizing the role of livestock and its potential to improve the livelihood of livestock value chain actors, AU-IBAR together with the technical partners with financial support from key donors including EC and USAID is implementing a number of interventions to support the prevention and control of TADs in order to promote safe intraregional and regional trade in livestock and livestock products. Such interventions include facilitating effective participation of African Countries in activities of the OIE, International Plant Protection Convention, Codex Alimentarius and WTO-SPS committees, during the formulation of international standards through the Project for enhancing Participation of African Nations in Sanitary and Phytosanitary Standards setting Organizations (PAN-SPSO). Given that TADs are a shared concern in the region, AU-IBAR in partnership with the IGAD Centre for Pastoral Areas and Livestock Development (ICPALD) with financial support from the United States Agency for International Development (USAID/EA) and the EU is supporting the Countries in the Region to build their capacity for surveillance and disease control through the Standard Methods and Procedures in Animal Health (SMP-AH) project that aims to standardize procedures for detection of, and response to specified trade-significant TADs and the Surveillance for Trade Sensitive Diseases (STSD), AU-IBAR is also supporting surveillance and disease control in Somalia through the Reinforcing Animal Health Services project. The other intervention with activities in the Region is the Veterinary Governance Project (VET-GOV). Ladies and gentlemen, Considering the impact of RVF on trade performance of the livestock sector in the Region, AU-IBAR fully supports initiatives, such as this one, that bring together the livestock exporting and importing countries in order to address shared sanitary concerns in livestock export trade. It is my sincere hope that this Forum will enable both parties to come up with a common understanding on the required sanitary measures as per the updated provisions of the RVF Chapter of the Terrestrial Animal Health Code with a view to facilitate safe and stable trade of livestock and their products between the two Regions in compliance with OIE standards and guidelines. I also look forward to such a Conference in the future in order to continuously address emerging needs for safe and stable trade. Distinguished guests, dear participants, Finally, I would like to thank once again, the OIE and FAO for organising this meeting within the framework of GF-TADs and for inviting AU-IBAR. I look forward to productive deliberations.

Senior Pan-AfAFRICADebre –

As youoccupyaffect origin.with a IndeedrecordmarketEast. Ihad diFebruaSomalanimaabout Ladies As youregionenableeffectithe su(and ttests fthese help d

OPEN

Diagnostics rican VeterinAN UNION – Zeit, Ethiop

u know, livey a place ofmany coun RVF, a disn undeniab

d, RVF can ed in 1997ting of animIndeed, there consequary 1998 toiland only. l imports, Ethe disease

s and gentle

u see, the ial or contine the develve veterina

uspicions ofime-efficien

for the diagndiagnostic kifferentiate

NING ADDR

Officer nary Vaccines

pia

estock in Aff prime impntries and ease presenle importan

adversely a7 - 1998 inmals (cattle ban imposences, espeo May 1999Even after East Africa e.

emen, distin

mportance nental cooropment of ry services’f illness. Thnt) diagnostnosis of RVkits also reqvaccinated

RESS BY TH

San

s Centre

LeCoMkDeExpeOIAf(Aancoof La

rica is faceportance. Thhave an im

nt in this regce, also bec

affect liveston Kenya an, sheep anded by the c

ecially in So9) were est2009, whenhas had to

nguished pa

of transboudination ancontrol pro linkages, ohis is turn tic tests at F come at aquire improv animals fro

- 20 -

HE REPRES

nne Charles B

et me firstommission kosazana Department oxcellency Rersonal capaE for the i

frican VeteriAU-PANVAC)nd work togontrol of RV

livestock.

adies and ge

d with majohe main anmpact on trgion of Africcause of its

ock trade bnd Somalia,d goats) frocountries of omalia wherimated at an the counto endure se

articipants,

undary disend the estaogrammes. one of whicrequires ada relatively

a relatively vement to eom those in

SENTATIVE

Bodjo

, on behalof the Afr

Dlamini Zumof Rural ERhoda Peaacity, exprenvitation th

rinary Vaccin) to participgether on oF and on w

entlemen, d

or issues, aimal diseasrade in anica, is one ofzoonotic na

etween cou have had m these cothe Middle

re losses dualmost USDtries of the everal years

ases such ablishment oSuch early

ch is the didequate laby affordablehigh cost to

enable earliefected.

OF AU - P

f of the Crican Unioma, the Coconomy ance Tumusess our sinchat was extne Centre ofpate in this ptions for t

ways to facil

istinguished

mongst whies have a cmals and pf these tranature.

ntries. For ea considerauntries to t

e East on live to the 16 109 millioMiddle Easts of revenue

as Valley Feof an early y warning sagnostic laoratory faci

e cost. The o African laber detection

PANVAC

Chairpersonn, Her Ex

ommissionernd Agricultuiime, and cere thankstended to tf the Africa important the preventitate the m

d participan

ich animal dcross-borderproducts ofsboundary d

example, ouable impactthose of thevestock imp

6 months’ baon for the rst lifted the e loss due

ever Rift rewarning sy

systems depboratory to ilities and ecurrently mboratories. n of the dise

of the xcellency r of the ure, Her

in my s to the the Pan-an Union meeting tion and

marketing

nts,

diseases r nature, f animal diseases

utbreaks t on the e Middle ports has an (from region of bans on to fears

quires a ystem to pend on confirm

effective marketed Even so, ease and

- 21 -

Research avenues for the development of new diagnostic tools need therefore to be promoted and supported, in particular for : • Rapid tests for use in the field, for the early detection of RVF cases; • Vaccines and tests to distinguish vaccinated from naturally infected animals. In order to compensate for the relatively high cost of diagnostic tests for animal diseases, a mandate was given to AU-PANVAC by the AU Member States to "produce and distribute essential biological reagents for the diagnosis of animal diseases" Since 2010, AU-PANVAC has started implementing this mandate with the establishment of the Production unit for reagents and laboratory diagnostic tests. Biological reagents and diagnostic tests (monoclonal antibodies, ELISA tests for the detection of antibodies against PPR virus of and mycoplasmatacae responsible for CCPP) have been developed and are undergoing the last stages of validation according to OIE standards. AU-PANVAC intends to continue its efforts, in close cooperation with other laboratories, to develop new diagnostic tools for priority animal diseases identified by member states, of which RVF is part. Ladies and gentlemen, AU-PANVAC, in addition to its activities pertaining to the quality control of veterinary vaccines, therefore also aims to contribute to the control of animal diseases in Africa through the development and production of diagnostic reagents. I would like to conclude my remarks by thanking once again, the OIE and also the Government of the Republic of Djibouti for hosting this workshop. Thank you for your kind attention.

DirectoAgriculIGAD SDjibout

is the StatesemployAgricuof live To be North improvtransb We relivestohad anbans a Ladieslivestostates concreoperat(ICPALthe regformuldomes

OPEIN

or lture and EnvSecretariat ti, Djibouti

richest regis is agriculying about

ultural Grossanimals in

specific, thAfrican couve our mark

boundary an

emember thock actors, n economicaffected all

s and gentleock and live

to improveete steps ttionalizationLD). Today gional liveslated and astication is u

ENING ADDNTER-GOVE

vironment Di

ion in livestlture with 75% of thes Domestic Africa cont

he region exuntries in 20ket share innimal diseas

he negativemainly of thc loss of abcountries in

emen, consstock produe food secuto promote

n of the IGICPALD is

stock projecapproved a under way i

DRESS BY TERNMENTA

Moham

vision

It’s all, Sec AlloapppeosupConhonwouIGAIGA The

tock resourcthe livesto

e populationProduct (A

tributing 42

xported 8.6 012 and 20the livesto

ses (TADs) a

e impact thhe produce

bout USD 4n the region

idering the ucts within urity and ine livestock GAD Centrsupporting

cts enhancinregional a

n the Memb

- 22 -

THE EXECUAL AUTHOR

med Moussa M

a pleasureon behalf

cretary of IG

ow me at preciation aople of Djibpport provinference. Snouring the uld also likAD for orgaAD headqua

e IGAD regioces. The maock sector, n and contrAgricultural 2% of the ex

and 9.2 m013 respectck trade, ar

and limited

hat heavilyrs, when RV

435 million who had th

high livestoand outside

ncome of thdevelopme

re for PastMember Stng TADs co

animal healber States (

UTIVE SECRITY ON DE

Mohamed

e and indeeof H.E. A

GAD to this i

the onset, and gratituouti for hosded durin

Special thaopening ce

e to thank anizing thisrter.

on covering ajor econom

mostly raibuting an eGDP). The xports from

illion live atively. The re limited ccoordinatio

y affected VF occurredin the two

he disease a

ock wealth e the regionhe communent, one btoral Areas tates in cooontrol and lth policy fMS).

RETARY OFEVELOPME

ed an honomba Mahboimportant R

to expressude to thesting the mg the orgnks to H.eremony of the OIE, F Conferenc

8 countriesmic driver ofised under estimated 5Region is tthe contine

nimals to thmajor bottle

capacity to cn capacity,

the livelihod in the reg bans (199and who had

in the region, the need nities, IGADbeing the s and Livesrdinating anivestock traramework a

F THE ENT

our to welcooub, the E

RVF Confere

s IGAD’s pe Governmemeeting andganization E. Mr Awathis Confe

FAO, AU-IBce in Djibo

s in Easternf the IGAD

pastoral s57% of the he leading

ent.

he Middle Eenecks, howcontrol andamong othe

ood of the gion. Somal99 and 200d not.

on, high deto support

D has takenestablishme

estock Devend implemeade. IGAD and the pro

ome you xecutive

ence.

profound ent and d for the

of the aleh for erence. I BAR and outi, the

n Africa, Member systems, regional exporter

East and wever, to prevent ers.

various ia alone

02). The

mand of member

n several ent and

elopment enting of has also ocess of

- 23 -

Moreover, IGAD is aggressively mobilizing resources for building resilience and enhancing pastoral livelihoods in MS through IGAD Draught Disaster Resilience and Sustainability Initiative or IDDRSI that has a primary objective of ending drought emergencies in the HoA. The regional projects and the resilience imitative are all contributing to TADs control, including RVF. Once again, I thank OIE, FAO. AU-IBAR and IGAD for organizing this inter-regional conference on RVF and bringing together relevant countries and stakeholders to discuss on “New options for trade, prevention and control of RVF”, thereby enhancing livestock trade from the region. IGAD confirms its commitment to jointly work with OIE, FAO, AU-IBAR and other partners, importing countries and Gulf Cooperation Council to strengthen and enhance the control and prevention efforts of Member States on RVF. I look forward to a fruitful meeting and wish you all an enjoyable stay in Djibouti.

MinisteMinistrDjibout

livesto Its smfacilitiof Djib I woulsecurean aniand hgovern Ladiesterms man, hthe ris Becaupassivsurveilhealth The bsurveilis, submajor

OP

er ry of Agricultti, Djibouti

ock trade fro

mall size, ites and its

bouti import

d also like e a singularmal-port, thuman capa

nment effort

s and gentleof commerchence the isk of this dis

se of the te surveillanllance targe services of

est performllance activbmitted to diseases su

PENING ADLIVESTOC

ure, Livestoc

om the HoA

ts harsh weliberal econtant advanta

to recall th cattle tradhe refurbishacities of tht.

emen, you acial livestocmportance sease appea

transboundance in the cets the risk f the French

ming quaranvities with re

strict diseauch as RVF.

DRESS BYCK, WATER

Hon. M

ck, Water and

It isof tcontand As impcoufirstintestar On RepSau

, a ban whic

eather condnomy focuseages for the

hat the Repe. Improvinhment of rohe institutio

are well awack trade. Whof the estabaring.

ary movemecontext of nareas in th

h army force

ntine centreegard to thiase control

- 24 -

THE MINIR AND FISH

Mohamed Ah

d Fisheries

s with pleashis importatrol of RVF, FAO for ch

you know,portant role ntries of thet quarantiernational strted operatio

this occaspublic, allowudi Arabia ch was put

ditions, itsed on the se regional de

public of Djng port infraoad and railons involve

are that RVFhen it appeablishment o

ents of animnational andhe country,es, stationed

e in the reis disease. measures,

STER OF AHERIES OF

hmed Awaleh

ure that I cnt Conferen in your pre

hoosing Djib

, the Repin the are

e HoA and ine centretandards, wons in late 2

sion and onw me to oncfor its wiin place be

strategic rervice sectoevelopment

jibouti contastructures, corridors,

ed in this a

F is the moars it causeof national a

mals, this d regional pin close co

d in Djibout

gion also pCattle, expoincluding

AGRICULTU DJIBOUTI

h

hair today’snce focusedesence. I waouti for this

ublic has a of cattle those of thee, designe

was establish2006.

n behalf ofce again thallingness tocause of RV

regional poors, represeof the lives

inues its fa including the strength

area, are al

st importanes mortality and regiona

periodic disprogrammesollaborationi.

participates orted from troutine im

URE,

s opening cd on preventarmly thanks Conferenc

always platrade betw

e Arabian Ged accordhed in Djibo

f Presidentank the Kino lift the VF.

osition, its ent for the Rstock trade.

acilitation ethe construhening of tell examples

nt sanitary hin both ani

al policies to

sease is sus. At nationn with FAO

in preventthe port of munisation

eremony tion and the OIE

ce.

ayed an ween the Gulf. The ding to outi and

t of the gdom of ban on

(air)port Republic

efforts to uction of echnical s of this

hurdle in mal and o reduce

ubject to nal level,

and the

tion and Djibouti against

- 25 -

At regional level, transboundary disease control programmes related to livestock trade are ongoing. In view of gaining a better understanding of the situation and achieve better control, there is need to conduct surveillance activities and field studies of these important animal diseases, the main ones being PPR, RVF, FMD and sheep-and-goat pox. These regional programmes are funded primarily by the EU and USAID, under the auspices of the AU-IBAR and FAO. The ultimate goal being to achieve harmonisation of animal health policies for the member countries of IGAD and of COMESA. There is no doubt that this conference will allow the experts that you are to take stock of the situation, to share experiences and make robust resolutions, not only in terms of the prevention and control of RVF, but also other transboundary diseases related to the cattle trade. I wish you a nice stay in Djibouti and the best of success in your work.

- 26 -

- 27 -

Session 1 Setting the scene

- 28 -

REC

ProgramScientiOIE Paris, F

Recom2014 The rethose recomwhich finding The se

• Ar

• Pe

• Ad

• L(

• R• S

a

CALL OF P

mme Officer ific and Tech

France

BRome, Italy

Mom

mmendationcan be foun

ecommendathat were mmendationswas target

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econd set of

At least thrregistration Production encouragedAccurate sdeveloped. Laboratory d(with the suRoutine vacSouth Africand educati

REVIOUS M

hnical Depart

Bloemfontein, 2008: http

Rommbasa, Kenya

s from thend here : ht

ations are pmade durings lists the sped mainly aVOs from a s

f recommen

ee vaccine trials and mand qualit

. erological t

diagnostic cupport of FAccination of ca is encouional tools t

MEETINGS,

Susa

tment

Rift previor Fimporegioof thFramDiseathe rwill prese2012

, South Africp://www.who.inme, Italy, 20a, 2012: http

last RVF Ttp://www.fa

resented ing all the abopecific and at vaccine selected nu

dations inc

candidatesmay offer nety assessm

tests for c

capacity forAO, OIE, IAE

populationsraged to shtargeting far

- 29 -

, THEIR OU

anne Münste

Valley feveous confere

FAO or oortance of Rns and sube diseases

mework for ases (GF-TArecommendbe present

ented in pr2, reference

Cairo, Egyptca, 2009: httnt/csr/resource011: http://wp://www.rr-afr

Technical Wo.org/3/a-i4

n two sets, tove listed pnew recomproducers a

umber of cou

ludes the fo

s (DDvax, New options i

ment of vac

camels (IgM

r RVF needsEA). s at elevatehare experiermers durin

UTCOMES A

ermann

er (RVF) hasences and mrganised j

RVF as one bsequently R

in the 5-yethe Contr

ADs) for thations and ted. For thevious mee

e is made to

, 2007: httpp://www.rr-afr

es/publicationswww.fao.org/drica.oie.int/do

Workshop o4466e.pdf

the first of revious meemendationsand researcuntries were

ollowing:

DV-GnGc, Mn the near f

ccines in l

M and IgG

s to be stre

d risk is encences suchg outbreaks

AND RECO

s been the meetings orgointly. Thiof the priorRVF can alsear action prol of Trane two regiothe action

hose that hetings such o the respec

://www.oie.inica.oie.int/en/es/WHO_HSE_Gdocrep/014/i2ocspdf/en/20

organized by

which suppetings, whils emanatingchers to repe in attentio

MP-12) are future. ine with th

G) and vac

ngthened, i

couraged. as commu

s.

MMENDAT

subject ofganised by is underlinrity diseasesso be foundplans of thensboundary ons. A sumplans for G

have alreadas in Mom

ctive online

nt/doc/ged/D4en_index_anneGAR_BDP_2002310e/i2310012/RVF/REP

y FAO in R

ports and ree the secon

g from this mport on theion.

being eval

he OIE Ma

ccines need

including ri

unication st

IONS

f several the OIE

nes the s for the d as one e Global

Animal mmary of GF-TADs dy been

mbasa in reports.

4246.pdf ex19.html 09_2c.pdf 0e00.pdf PORT.pdf

Rome in

eiterates nd set of meeting, ir recent

uated in

anual is

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ng trials

trategies

RegionECTADFAO Nairob

RVF woccurrand 1livestoperiodaverag

RVF IN T

al Manager D Eastern Afr

i, Kenya

was first dering as spor936, RVF

ock were raiss1936 to1

ge inter-epiz

THE HORN

ica

escribed inadic cases.was confinsed in proxi950. From zootic period

OF AFRICAA HIST

RVprbuhuananhureanthtraarspco

T

n Nakuru D The virus,

ned to Nakimity with w1951 to 2

d of 3.6 yea

- 30 -

A, EAST AFTORICAL OV

Bouna Diop

VF is a Phrimarily afuffalos, drumans. Shend cattle nimals get uman caseseleased durnimals. Nevhe bite ofansmitted rthropod sppread wideonditions ar

Text and cred

District of however, wuru District

wildlife. No 2007, elevears.

FRICA, ANDVERVIEW

p

hlebovirus affects sheomedaries, eep are theare somewinfected t

s are attribuing slaughtvertheless, f infected by a larg

pecies and ely and rre conducive

edit

Rift Valley was first isot which is RVF outbre

en RVF epiz

D THE MID

arthropod-bep, goats,

antelopesmost susc

what less shrough moted to contatering or coman can a

mosquitoege and dtherefore i

rapidly whe.

province ilated in 19prone to faks were rezootics were

DDLE EAST

borne zoono, cattle, , wildebee

ceptible whisusceptible

osquito biteact with bodontact with lso be infees. The viverse numit has potehen enviro

in Kenya i931. Betweeflooding aneported betwe recorded

osis that camels,

est, and ile goats e. While es, most dy fluids viremic

cted via virus is mber of ential to onmental

n 1912 en 1912 d where ween the with an

- 31 -

RVF reports outside Kenya begun in 1950s where between 1951 and 2007, large RVF epidemics have been reported in many African countries. In 2000, the disease was detected in the Arabian Peninsula, having spread outside of Africa for the first time. Somalia experienced the last two major RVF outbreaks in Eastern Africa. Between December 2006 and February 2007, the disease was reported in both humans and livestock in many regions including: Gedo, Lower and Middle Juba, Lower and Middle Shabelle, and Hiran. In Sudan, the first evidence of RVFV presence was described in 1936 while the first recorded epizootic occurred only in 1973 in sheep and cattle in White Nile State. Since then, RVF sero-positivity has been shown in different Sudanese states. The last outbreak occurred in 2007 in several Sudanese states along the white and blue Nile. In Tanzania, the most notable epidemic occurred in 2006-2007 although events were also reported from 1947 to 1998. Average inter-epidemic period is 7.9 years (3-17). During the period 1930 to 1979, the cases were confined to four districts in northern Tanzania. From 1980 to 2007, RVF was reported in more areas located in north to east, central, and southern regions. In Egypt, the largest RVF outbreak occurred in 1977–1978. Despite biannual vaccination with inactivated vaccine, a second outbreak occurred in 1993–1994. The vaccination campaign (using Smithburn vaccine) performed during the outbreaks of 1996–1997 and 2003 did not stop the disease. The reasons remain undetermined but could have contributed to the unusually short inter-epidemic periods observed in Egypt. In September 2000 RVF epizootics were identified in Saudi Arabia and Yemen. The Tihama/Jizan regions of Yemen and the southwest Saudi Arabia (Gizan region) were principally involved. RVF remains a regional concern and more collective action is needed to prevent and control the disease.

(*) ProgSub-ReOIE Tunis,

reporteProjececologincreas After 1the zo– whic The u2010 represAnimaundouidentifcontexmolecprelimsurveil Today zone -been dMauritLittle M The recontinan effRepresactivit

REC

gramme Offiegional Repre

Tunisia

ed 1987 aft. This con

gical characse mosquito

1987 outbrnes at the b

ch is consid

nexpected with majorents a serio

al Health Nbted sustafied RVF asxt - and undular and se

minary assesllance of th

an endemi- so called detected uptania and pMaghreb.

e-occurrenceuous threatfective survsentation foies in line w

CENT RVF O

Acer esentation fo

fter the buinstruction - cteristics suo breeding s

reaks were rborder betwered a suita

occurrence r impact onous threat f

Network (REinable link

s one of theder the umberological dssment of is disease in

c zone canLittle Mag

p to date. Itpermanent

e of RFV int for the entveillance syor North Afrwith the OIE

OUTBREAK

Alessandro Ri

or North Afric

lding of theand its re

ch as the csites.

reported regween Senegaable environ

of RVF in n both humfor the entirMESA) plat

k between e priority disbrella of REMdetection othe diagnon the REME

be recognighreb (Morot is also ackpassive sur

n Mauritaniatire region aystem in thrica is provE Internation

- 32 -

KS IN NORT

ipani* & Rac

ca

RVF is a single serohuman acharacterineonatal African coccurring breeding o Data repovirologicalcirculationwithout nosubstantiawhich cau

e Diama daelated floodcreation of

gularly fromal and Soutnment for ve

the northeman and anre Maghreb tform - whithe CVOs seases to coMESA the fof RVF viruostic capabESA zone.

ised in the occo-Algeriaknowledgedrveillance a

a in Octobeand that mohe region.

viding supponal Standar

TH AND WE

chid Bougued

viral vectootype of theand animazed mainly mortality -ontinent anin climatic of mosquito

orted in thel or serolon in the Wesoticeable clal outbreakused more m in the frings - led more water

m the West Ahern Mauritector popula

ern Sahelianimal healtharea. For t

ch is an ofon both sontrol in thfirst Externaus was orgaility of the

Western paa-Tunisia) - that an aclong with o

er 2013 coore targeted

In this coort to theseds.

ESTERN AF

dour

or-borne dise Bunyaviridal health. by high ratis nowada

nd Arabianconditions s.

e published gical evidest African reinical manif in the Wthan 200 amework ofto the chan accumulat

African regitania - alongations.

n region of h, confirmedthis reason, fficial netwoides of thee North Afr

al Quality Asanized in oe laboratorie

art includingwhere the

tive surveilloccasional s

nfirmed thaactions are

ontext, the e countries

FRICA

sease causedae family a

The distes of abortays presentn Peninsulawhich facil

literature ence of RVegion prior festations. T

West Africanhuman deaf the Senegnges of somtion points

ion but geng the Seneg

Mauritaniad that this the Mediteork that cree Mediterrarican regionssessment sorder to pees involved

g Mauritandisease ha

lance is in sero-surveys

at this disee necessary

OIE Sub-Rto impleme

ed by a affecting sease - tion and t in the a mostly itate the

revealed VF virus to 1987 The first n region aths was gal River me local so as to

erally in gal River

a in late disease

terranean eated an anean – . In this study for erform a d in the

ia and a as never place in s in the

ease is a to build

Regional ent such

(*) ResOndersARC - OPretoria

South laborat The disof anim(e.g woresult o Six couwere TaoutbreaThe mato a leinside t During MozamHowevebeyond RVF is RVF. TClone 1indicatinvestig The chalways other cabortioOVI. Pumake sbenefit

searcher Virostepoort VeteOVI a, South Afri

Africa in 20tory-confirme

sease has semals and humool, beef andof RVF outbre

untries in SAanzania, Madaks followed ajority of aniesser extent. the countries

the same pembique, Zamer, it is possd detection li

a notifiableThe vaccines 13. High motive of RVF. gate the situ

hallenges facready when

challenge is ton. During thublic educatstakeholders ts of preventi

RECENT

logy Departmrinary Institu

ca

10 with 14,ed human cas

vere direct amans affectedd milk). Peoeaks.

DC reported dagascar, Naheavy rainfamals affecteTo manage

s were contro

eriod, no RVFbia and Zimible that themits.

e disease in that are currrtality rate ofVeterinary

ation.

ed by South the outbrea

that the inithe period 20ion programmaware of th

ing such dise

RVF OUTB

Rachel Ma

ment ute

RVinwibySihaBoEgmThanra SiSoun

342 animal ses with 26 d

and indirect sd by the diseople whose l

RVF outbreaamibia, Botswlls. The outb

ed were shee the outbrea

olled.

F outbreaks wmbabwe. Thuere was no su

South Africarently availabf young animand human

Africa regaraks occur andial symptoms05-2014, 8 mes/farmer ae nature of

eases. - 33 -

BREAKS IN

aluleke* & P

VF is a disecluding humild animals. Ty competent nce the dise

as been repootswana, Nagypt and Seortality amohe susceptibnimal specieinfall and flo

nce the firstouth Africa,npredictable cases and 8deaths were

socio-economease. In-direcivelihoods d

aks in the pewana, Swazilbreaks occurrep and cattleaks, animals

were reporteds these cou

urveillance d

a. Farmers able in South

mals, abortionhealth auth

rding RVF ard vaccines cs of RVF can600 sample

awareness anthe disease,

SOUTHER

Phelix Majiwa

ease which amans, sheep,The virus resmosquito spe

ease was firsorted in, amoamibia, Zamenegal. It is ng young anility of the as. Outbreaks

oods.

t case of RV there havintervals. Th

8,877 animaidentified.

mic impacts. ct impacts inepend on th

riod spanninand and Soured in both ce. Goats and s were vacci

d in Lesotho,ntries are coone or the vi

re advised toAfrica are Sm

n in animals ahorities shou

e that the dicannot be ston be confusees from animd other publ consequenc

RN AFRICA

a

affects a widcattle, goat

sponsible for ecies, such at diagnosed

ong other coumbia, Mozam

characterisenimals and animal host s of RVF no

VF was obsere been spo

he latest outbl deaths. Du

Direct impaclude decrea

hese kinds of

g 2005 to 2th Africa. In ommercial abuffaloes wenated and m

Angola, DRConsidered freirus might be

o vaccinate tmithburn, inaand febrile d

uld be inform

sease is spoockpiled for ed with othermals were tesicity campaigces of livesto

de variety ofts, camels athe disease

as Aedes andin Kenya in untries, Soutmbique, Maded by high abortion in depends on

ormally follow

rved in the 1oradic outbbreak was rering this per

acts include tase/loss of pr

of income su

014. Those all the counnd small scaere also affemovement of

C, Malawi, Mee from the e circulating

their animalactivated vacdisease in humed immed

oradic, peoplvarious reas

r diseases thsted for RVFgns are oftenock diseases

f animals and some is spread

d Culex. 1931, it

th Africa, dagascar, levels of animals. age and

ws heavy

1950s in reaks at ported in riod, 242

the dying roduction ffer as a

countries tries, the

ale farms. cted, but f animals

Mauritius, disease. at levels

s against ccine and mans are iately, to

e are not sons. The hat cause F at ARC-n done to s and the

- 34 -

- 35 -

Session 2 Challenges to

disease control

- 36 -

Chief RKenya KEMRINairob

Duringavailab Duringavailabcontro To be high rthreat Unfortno covaccin Publicmeasuquaranlivesto Vectorthat acaffecte

Research OffMedical ResI i, Kenya

g the normble for contr

g the pre-oble control ool, and publ

effective, lisk and a pof an RVF o

tunately, theuntry in th

nation is not

c educationures against ntine and sock producti

r control, prccompaniesed areas and

icer earch Institu

mal phase (rolling the d

outbreak (ooptions incic education

ivestock vacposition on routbreak.

ere are few he HoA hat recommen

, livestock disease sp

slaughter baion systems

rimarily thros RVF outbred cost.

AVAILABL

ute

Thehavpeothe As ato devidenandof ithe the

(non-epidemdisease is liv

outbreak walude liveston.

ccination reroutine vacc

broadly liceas a clear ded during

quarantine,read duringan for a lon and food o

ough aerial eaks but it

- 37 -

E CONTRO

Kariuki Njen

e periodic Rve a significople living i

local, natio

a step towathe epidem

veloped a dntifying thed decreasingnterventionepidemicsspecific sta

mic period)vestock vac

arning) andock vaccinat

equires a clecination an

ensed RVF policy on an outbrea

, and slaugg an outbreang time sinof animal or

spraying, has limited

OL OPTIONS

nga

RVF epidemicant impacin the regioonal, and re

ards improvimics, regiondecision su sequence g the RVF es that can b, and matcage of the R

of the RVccination.

d outbreak tion, quaran

ear nationald emergenc

livestock vaRVF vaccik.

ghter ban aak. There isnce many aigin is the p

is often atteffectivene

S

ics in the Hct on lives on, and thegional econ

ing managenal and inpport tool fof events reepizootic risbe used to ching these RVF disease

VF cycle, t

phases ofntine and sla

l policy thatcy vaccinati

accines; andnation. In

re perhaps s often a proaffected areprimary diet

empted duess due to ex

Horn of Africand livelih

ey negativenomies.

ement and rternational for the purelated to insk, compilinprevent and

e interventio cycle 1.

the primary

f the diseaaughter ban

t identifies ion in the f

d to our knoaddition, l

the most eoblem of sueas have pa.

ring heavy xpansivenes

ca (HoA) hoods of ly affect

response experts

rpose of creasing ng a list d control ons with

y option

ase, the n, vector

areas at ace of a

owledge, ivestock

effective ustaining astoralist

flooding ss of the

V

ConsulResearGALVmLichtaa

The bicandid RVF, dAfrica aspecthas a Based econom As a rthe incrather vaccinstrateg Combiimportimmunvaccinwell asencour Externcentracreatinincreas

ACCINATIO

tant ch Departme

med art, Belgium

iggest challdates to the

despite beinas well as

t a rather locharacterison limited

mically just

result the mcentive for limited. Va

nes for emegy in a RVF

nation vactant ruminanization, hanation, expas to end useraged.

nal control alized qualitng an equase attractive

ON STRATE

ent

enge howevmarket and

ng a seriouin some couw or moder

stic epidemd economic ify or suppo

motivation focommercia

accine or anrgency use.control prog

cines offerant diseaseave the pond the marers. Their d

and qualityty control

al level playeness to com

GIES, VAC

D

t

ver will be d to implem

s economicuntries of thately attractic outbreakdamage in

ort vaccinat

or the broal companientigen bank All of this gram.

ing protectes, resultinotential to ket and the

development

y harmonizaand regulaying field, mpanies to

- 38 -

CINE AVAI

Danny Goovae

Both inactiare availablthe field. Hand efficacimproved R Recently seDNA, subuunder develicensed. For some, have been efficacy of t the task of

ment them in

cal and enzhe Middle Etive disease

k cycle dep between laion or vacci

d consistenes to seriousks can play s highlights

tion againsg in broaddecrease

refore be att and comm

ation of RVatory platforharmonizininvest in RV

LABILITY A

erts

vated as wele and have

However thercy of thesVF vaccines

everal imprunit or repelopment,

promising demonstratthese vaccin

further comn a well-des

zootic endemEast, is frome. The diseaending on arge epidemnation cam

nt use of RVsly invest ina role in athe need fo

st not only der and lonoverall cos

ttractive botmercializatio

F vaccines rm. This c

ng regulatorVF control.

AND QUALI

ell as live abeen in us

re still is a se vacciness for livestoc

roved live alicon vacciin the lic

results or ted with resne candidat

mmercializasigned contr

mic diseasem a commerc

se besides climate, raimic outbreapaigns to co

VF vaccinesn RVF vaccn improved or a well-de

RVF but ng term prsts, increasth to vaccinon should th

is needed ould certairy requirem

ITY CONTR

attenuated vse for a longgap betwee

s and a nck.

attenuated,ne candidaensing pro

proof of cspect to saftes.

ation to brinrol program

e in a largecial vaccinebeing endeinfall and faks it is difontrol the d

s and consecine develop availabilityesigned vac

also againrotection wse uptake ne manufactherefore be

as well asnly play a

ments and t

ROL

vaccines g time in en safety need for

vector, ates are ocess or

concepts fety and

ng these .

e part of e market mic also flooding. fficult to disease.

equently pment is y of RVF ccination

st other with one

of RVF turers as strongly

a more role in

therefore

VA

(*) ChieResearOndersPretoria

The seattenumakingvirulenwhen a The thisolatedeletioThe mshort sfocusestoragedeman The stcertainreques

ACCINES :

ef Scientific ch and Deve

stepoort Bioloa, South Afri

econd avaiuated live vag it a cheance of the Sadministere

hird vaccineed from a bon in the NS

major challenshelf life oed on idente to allow nd periods.

tudy will an African csts.

VACCINES

Bo

Officer lopment Depogical Producca

lable vacciaccine usedaper alternaSmithburn sed to gestati

e available ibenign humaSs gene whnge that haf the vaccitifying appr

vaccine av

lso providecountries b

S CURRENT

oitumelo Moeand B

partment cts (OBP)

Rinimpthlith Chdaaha

ne is the d since 195ative to thetrain; there ing adults.

s the RVF Can case in ich renders

as been assne productopriate metvailability t

some insibased on O

- 39 -

TLY USED

ethloa, NobalBethuel Ntha

RVF outbreandustry andmpact is population. his vector-bvestock phrough cons

Currently Ohas three redisease. Adjuvanted Rn infected

hamster kidn booster vac

modified R51. This vace inactivated

is a potent

Clone 13 vaCentral Afr the virus aociated wit. This presthods and to customer

ghts in theOBP RVF v

IN THE FIE

landa B. Mabangeni*

aks have add with the most ofteThe most e

borne diseaspopulations sistent annu

Onderstepooregistered vaAn inactRVF virus vbovine and

ney (BHK-2ccination an

RVF Smithbccine is abld vaccine. ial risk of th

accine whicica Republ

a-virulent in h RVF Clonentation wifacilities fors in a lim

e possible vaccine pro

ELD AND T

bizela

dverse impadisease bei

en spread effective mese is ensuri

have imual vaccinat

rt Biologicaccines for ivated alvaccine isold adapted f1) cells. Th

nd annual re

burn virus se to provideHowever, d

he virus to c

ch is a live ic. The stramice, ham

ne 13 has bll highlight

or bulk RVFmited time

RVF vaccinoduct regis

HEIR ISSU

act on the ling a zoono

into the ethod of cong that sus

mmunity ation program

cal Productsthe controlluminium-hated in 19for growth his vaccine e-vaccinatio

strain whice lifelong imdue to the cause terato

attenuated ain contains

msters and libeen instab research a

F Clone 13 frame duri

nation stratstration sta

UES

livestock osis, the

human ntrolling

sceptible achieved mmes.

ts (OBP) of RVF ydroxide 74 from in baby requires

on.

ch is an mmunity residual

ogenicity

vaccine s a large vestock. ility and activities

antigen ng high

egies of tus and

ResearResearDeltamLyttelto

segmenthe tarrobust viremiaclearly abortogEntomowhich tthe poselectioprocessFisheritrials w SignificNewcaspotentiseries osite of from vaDelibernaturalexposeenvironcontainof diffeinduceagainstis plan

ch Veterinarich & Develop

mune on, South Afr

nts respectivrget livestockimmunity ag

a and abortiodemonstrate

genic potentological studtogether withssibility of son. This vacs. Approval ies (DAFF) towill be submi

cant progresstle disease ial environmof safety triainoculation, accinated tarate vaccine l NDV, the red to the tis

nmental safnment. Subserent adjuvad demonstrat clinical disened for this v

V

ian pment

rica

vely, showed k species. Against RVF won. Vaccinatied that RVF tial and, wdies also shoh the absencspreading in ccine candidahas been gr

o use the vactted in the n

s has also bvirus-vectoreental risk of

als. The resudoes not carget species administratioecombinant vssues of vacety study, equent trials

ants suitable able levels of ease and viravaccine cand

VACCINES

L

Alcocorethim Mgevava MandeThan

an excellentseries of tr

which can fulon experimevirus lackin

hen used cowed that thee of significathe environ

ate is now aanted by thecine outside ear future.

been made wed vaccine ex this recomblts of these suse significa(sheep) to i

on to avian hvirus failed tccines by th

DAFF apprs focussed on

for use witneutralising

aemia. A fulldidate in the

- 40 -

: NOVEL V

Louis Maarte

though the contributions toncerns withquirements oe search for

mportant dise

any differenenetics technaccines and arious stages

ajor advancend efficacy eveloped throhis attenuatend NSm get safety profrials in pregnlly-protect hents in first-tr

ng these noncorrectly, alse absence oant levels of nment and gapproaching e South Africontainmen

with regards xpressing thebinant virus studies indicant levels of in-contact cohosts resultedto infect fullyhe oral routeroved furthen optimisatioth live antige antibodies a safety and enear future.

ACCINES (

ens

currently-avato the contro some of thof countries anovel improv

ease.

nt vaccinationology, recoadjuvanted sof evaluation

es have been of a promisough the useed strain, whenes on thefile in laboranant-ewes ineavily-pregnarimester pregn-structural vso an extref the NSm-gviremia in th

gaining virulethe pre-regiscan Departmt and applica

to the safete Gn and Gcwas assesse

cated that NDviraemia in tontrol animad in seroconvy-susceptiblee. Based oner vaccination of the vacens. Two forand durable efficacy eval

1)

ailable vaccinol of RVF in ehese productat risk in nonved vaccines

on platformsmbinant (vesubunit vaccn.

made in the ing new RVe of reverse hich lacks the small andtory animal

ndicated thatant animals agnant ewes (4virulence facmely low te

gene impairs he vaccines, ence under cstration phasment of Agrications for aut

y and efficaglycoprotein

ed under BSDV-GnGc remthe vaccines ls or birds (sversion of thee in-contact

the favouraon experimccine formulrmulations wimmunity (> uation in the

nes have maendemic areats and the rn-endemic ars against this

s, includingector) vaccincines are cur

e assessment VF vaccine c

genetics teche non-structd medium models as wt this strain against clinic42 days of g

ctors has a neratogenic p

s insect transpractically econditions ose of the assiculture, Forethorisation to

acy testing on genes of RSL3 containmmains localis and does nosheep and ce vaccines, bcontrol birdsable outcom

ments outsidation by the

were identifie5 months) p

e pregnant ew

de major as, safety regulatory reas drive globally-

g reverse nes, DNA rrently in

of safety candidate chnology. tural NSs genomic

well as in provides

cal signs, gestation) negligible potential. smission, liminates

of natural sessment estry and o do field

f a novel VFV. The

ment in a ed at the ot spread hickens).

but unlike s or birds

me of the de BSL3 addition ed which protective we model

(*) DireMCI SaRabat,

In thiswhich produccycles using effect,

A pilosheep,detectprobabtool fo

The neunlikeanimadiffusi

C61 cfield.

ector of R & anté AnimaleMorocco

s study, we is a natura

ced on Veroof heating

the high di, high titer a

ot batch of , goats and ted as soon bly more. Tor Rift Valley

ew Clone 6ly to reversls showed von.

andidate RV

V

MeD

e

isolated a ally attenuao cells, hea and cloninlution methand better s

RVF C61 camels usias two wee

he vaccine y fever cont

61 vaccine se to virulenvery low or

VF vaccine

VACCINES

ehdi El-Harra

RVSaspecoan

Vaexppreimvac

Th(Cl(Sm

thermostabated strain ated at 56°ng were perod. The C6

stability if co

vaccine hang virus neueks after vais stable atrol in endem

candidate nce in addino viremia

should now

- 41 -

: NOVEL V

ak*, S. Daoua

VF is a vectaharan couread to theonomical lod also hum

ccination ispansion of eferable to

mmunogenicccination.

he availablelone 13) omithburn st

ble vaccine because of

°C and resisrformed and61 showed aompared to

s been proutralization accination at 4°C for twmic countrie

is derived fition to its at all when

w be tested

ACCINES (

am & K. Tad

tor borne dntries, incle Middle Eaoses in livean fatalities

s the only wthe disease

o inactivateity, lower p

e live vaccr cause abotrain).

candidate (NSs gene

stant viral d the most a characteri other clone

oduced andtest. Good

and they laswo years anes, once com

from the depotential a tested by

on large sca

2)

dlaoui

disease, endluding Wesast since 2estock (rums.

way to prevee. Live attened ones brice and no

cines are eortion and

Clone 61) fdeletion. T

particles weresistant cstic and prees or the ori

tested for levels of anst for a mind could repmmercialise

eleted Clons a DIVA vPCR which

ale for mass

demic in mst Africa a2010 causiminant and

ent and connuated vaccbecause ofo need of a

either thermteratogenic

from the ClThis virus here selectedlones were ecocious cyiginal C13 s

efficacy inntibodies hanimum of opresent an ed.

ne 13 strainvaccine. Vacreduces th

s vaccinatio

most Sub and has ng huge camels)

ntrol the cines are higher booster

molabile c effects

lone 13, has been d. Three purified

ytopathic strain.

n cattle, ave been one year, efficient

n and is ccinated e risk of

on in the

D

Head oOndersARC-OVPretoria

purpos As parRVF ba 1.

2. 3.

4.

Great date. availabthe sktrainincontribgeneraimprov

DIAGNOST

of Virology Destepoort VeteVI a, South Afri

se, turnarou

rt of endeavased at ARC

Invests inpurchase working wDevelops oContinuouincluding Harnessesmaterials, assay deve

strides havNonethelesble tests. Rkills neededng in diagnbute to quaate knowledvement of c

IC TESTS F

epartment rinary Institu

ca

und time an

vours to addC-Onderstep

providing of personalith live RVFor establish

usly validatparticipatio

s collaborattechnical

elopment, o

ve been mas further ineference Lad to providnostic testality assurage and tool

current assay

FOR RVF AWHAT

Bara

ute

d DIVA cap

ress some opoort Veterin

a safe wor protective

FV; es various ates the meon in inter-laions with rskills and

optimization

de in the dnvestigationaboratories cde diagnosting, producnce of the s that couldys.

- 42 -

ND ROLE OT IS AVAIL

atang Alison

Rift Vallthe BueconomiAfrica aremains susceptiregistereusually epidemioevaluatioserologicantigen biosecursubmitteavailabil

acity, rema

of these chainary Institut

king enviroequipment

assays to meethods thraboratory teresearchers information and validat

developmens are key tcan mobilistic testing ce reagentsmethods th

d be used in

OF REFEREABLE?

Lubisi

ley Fever vunyaviridae cally devand the Arthe only p

ble livestocd for hum

done fological sons and cal, virus i

identificatity regula

ed and histity, affordin major ch

allenges, theute undertak

nment to it and maint

eet differenough form

est compariselsewhere

n used in rtion.

t of differeto addressinse financial for variouss, develop hrough ILTCn developme

ENCE LABO

virus (RVFV)family,

stating zooabian Penipractical cock, and thmans. Diagfor diseastudies, export ce

solation, Rion methodations, typtory of the dability, vallenges in

e OIE Referes the follow

nclude perstenance of

t testing reqal and exsons (ILTC);in the wor

research, in

nt RVF diagng limitatioand other r purposes, and valid

C with otheent of novel

ORATORIES

), a Phlebocauses RVonotic diseinsula. Vacontrol mea

here is no gnostic tesase confivaccine ertification,

RNA detectds. Biosafepe of spanimal, an

validation RVF diagno

rence Laborwing:

sonnel vaccBSL3 facil

quirements;xtensive pr; rld for exchncluding di

gnostic metons of the cresources, a

execute tedate test mer laboratorl diagnostic

S :

ovirus in VF, an ease in ccination sure for vaccine

sting is rmation, efficacy using ion and ety and pecimen nd assay

status, oses.

atory for

cination, lities for

; ocesses,

hange of agnostic

thods to currently and have echnical

methods, ies, and

c tests or

RO

Head oOndersARC-OVPretoria RepresRegionOIE Beirut,

milk o The ccruciaRefereresour There southeor at c The OSouth RVF dNeutravarious The ereferenthrougcontrib

OLE OF RE

of Virology Destepoort VeteVI a, South Afri

sentative al Represent

Lebanon

r, similar to

linical signl for mobili

ence Laboraces necessa

are only tern hemisphclose proxim

IE twinningAfrica and

diagnostic calisation Tess aspects of

stablished nce laboratogh self-suffbuting to go

FERENCE

epartment rinary Institu

ca

tation for the

o other susc

s caused bisation of reatories oftenary to perfor

two OIE Reheres, in Fr

mity to all th

g project on the Centracapacity in est (VNT), Rf laboratory

scientific aory status foficiency in ood veterina

LABORATO

Baratang Al

ute

e Middle East

RcBafhd1coAimta

eptible anim

by RVF are esources an perform dirm the diffe

eference Laance and Se RVF enzo

n RVF betwal Veterinary

Yemen, inT-PCR and quality ass

and technoor RVF, whi

the earlyry governan

- 43 -

RIES : TW

Alison Lubisi &

t

RVF is an ecaused by tBunyaviridaamong neonflu-like symhumans, chdiagnosed i1931 and wcountries soutside the Arabia, follinfected wmosquitos othrough manimals, comals, throug

not pathognd institutiosease confi

erent assays

aboratories South Africaootic regions

ween ARC-Ory Laboratoryn the form

qRT-PCR aurance.

ological expch would be

y detectionnce.

INNING (S

& Ghazi Yehi

economicallhe RVF viru

ae family. Anates in su

mptoms whiharacterise in sheep inwas found tsince then.

African coowed by Y

with RVFVor in-utero.

manipulationnsumption gh bites of i

gnomonic aon of contrormation sin

s required fo

for RVF, sa, respectives to facilitat

Onderstepoory (CVL) in of differen

and virus iso

pertise will enefit the e

n and diag

OUTH AFR

ia

y devastatinus (RVFV), abortion storsceptible aich can proRVF. The

n the Rift Vo be enzoot

The first ntinent was

Yemen in 2through

Humans co of carcaof infected infected mo

and laboratool measuresce they hav

or the purpo

situated in ely. Their loe prompt ou

ort VeterinaryYemen is at antibody olation in d

hopefully entire Arabiagnosis of

RICA – YEM

ng zoonotica Phlebovirurms and monimal specogress to d

disease wValley of Ktic in manyincursion

s recorded i2000. Animbites of ontract the asses of and unpas

osquitos.

ory confirms during ouve the experose.

the northocations areutbreak resp

ry Institute aimed at in

ELISAs, thifferent me

earn the Can Peninsulthe diseas

MEN)

disease us in the ortalities ies, and death in was first Kenya in y African

of RVF in Saudi mals get infected disease

infected steurized

mation is utbreaks. rtise and

ern and e not in, ponses.

(OVI) in creasing he Virus dia, and

CVL OIE a region

se, thus

ResearResearDeltamLyttelto

from thabsenc Antigeninfectestandapolymesensitivdifferentechniqconsidecloselyhoweve The vevolumevariety specificAn IgMenables There diagnosassays,sufficie Climatiinteres(e.g. a microaof thes

ch Veterinarich & Develop

mune on, South Afr

he fourth dace of IgM sign

n can be deed animal carrd virus isolerase chain vity, specifintiation of ceques is takinered the gold-related buner, not suitab

ersatility andes, resulted iof indirect acity profiles

M-detecting s efficient de

is a need fses. Althoug, these testsent sensitivity

ic change ant in the deve multiplex trray or fluore

se are freely a

A PRACDIAGN

ian pment

rica

ay post infecnifies previou

etected in thrcasses usinglation in celreactions (rtcity and reertain RVFV g place contden standard

nya viruses dble for handli

d suitability in consideraband competitbut, are restblocking ELetection of re

for inexpensh promising s are still noy.

nd the potentelopment of mest for arboescent microavailable yet.

CTICAL PEROSTICS AN

L

RVnotheof fift(e.as virsh(deresslomaressinan

ction until aus infections

he blood, serg a variety ofl culture or -PCR) have eaction timevaccine stra

tinuously. Vird for antiboddoes not inteng large sam

of enzyme lble developmive ELISA’s,

tricted in termISA is availaecent infectio

ive, reliable results have

ot readily av

tial of RVFV tmultiplex assvirus infectiosphere immu.

- 44 -

RSPECTIVEND FUTUR

Louis Maarte

VF is a peraotably of rume blood and time (generath to the se.g. in very yosixteen hou

remic stage ow a proemonstrable sponse usuaowly declinesany years. sponse may nce the prenimals is a repproximately with negligi

rum and plaf diagnostic t suckling mbeen develoe. A recen

ains from fielirus neutralisady detection erfere with t

mple volumes

linked immument and con

are availablems of their uable which ons.

pen-side tebeen obtain

vailable for u

to spread to says to facilitons). Prelimunoassay tec

E ON CURRE DEVELOP

ens

acute to acminants and m

serum of infeally from theeventh day pung animalsrs post infeccan persist ominent ne

from aboully peaks 14s to a stablFurther ch

provide impoesence of Igeliable indicay day 50), wble risk of ac

asma of viremtests. Infectio

mice. A largeoped with sigtly-developedld strains. Re

sation tests (Vagainst RVFthe interprets.

une-sorbent ntinuous impe. Most of thuse for sampcan be used

ests to facilned with immuse in the f

previously utate syndrominary results

chnology (Lum

ENT RVF PMENTS

cute viral dman. Antigenected animal second to th

post infection) viremia canction and in up to day 1eutralising t 5 days p

4 to 21 dayse plateau w

haracterisatioortant epidemgM antibodietor of recent

while the prective replicat

mic animals ous virus cane variety of gnificant advd multiplex efinement ofVNT), althoug, since crossation of this

assays (ELISprovement ofhese have excles from mud across the

itate promptmune-chromaield and in

ninfected areic testing in

s obtained wminex), are e

isease of mn can be dels for a limitehe third day n). In extremn be detectedsome individ

12. Survivingantibody

post infectios post infect

which may pon of the miological infes in the s infection (desence of Igion.

s or in the tn be demonsreverse tranvantages in

rt-PCR allf the differengh laboriouss-reactivity ws assay. The

SA) for largef these techncellent sensitltiple animal

e species ba

t and accuratographic latmany instan

eas, sparkedhumans and

with assays bencouraging

mammals, tected in ed period until the

me cases d as early duals the g animals response

on). This tion, and ersist for humoral

formation serum of etectable

gG in the

issues of strated by nscriptase

terms of lows the nt rt-PCR , are still

with other e VNT is,

e sample niques. A tivity and species. rrier and

rate field teral flow nces lack

renewed d animals based on but none

CH

Senior Pan-AfAU Debre –

RFV iBunya Implemearly dantigediagnosurveilbased is alsodevelodiagnomultip The rea majowith itthe coand prthe dcollaboidentifsuppordocumproduc

ALLENGES

Diagnostics rican Veterin

– Zeit, Ethiop

s caused baviridae, gen

mentation odetection sns and antostic tests llance of thtests which

o a need opment of osis (neonatplex assays w

elatively higor challengets continentontrol and eroduction ofdiagnosis ooration witfied RVF asrt from AU

ment on AUction of biol

S TO CONT

Officer nary Vaccines

pia

by a singlenus Phlebov

of appropriaystems. Thibodies are for detect

he RVF diseh are currento differennew RVF vtal mortalitywhich can d

h cost of coe to Africantal mission

eradication of essential dof priority h African s one of the-PANVAC i

U-PANVAC logical reag

ROL RVF DD

Sanne-Charle

s Centre

RVTradraThcou19affduestregwamacon

e serotype virus.

ate control e laboratoressential t

ion of RVease. Therently not avaitiate naturavaccines any and abortidifferentiate

ommercial dn laboratorie“to promot

of animal ddiagnostic rdiseases.

laboratoriese priority dn this regaDiagnostic ents for RFV

- 45 -

DISEASE : RDIAGNOSTI

les Bodjo* &

VF is a ansboundaryamatically ae ban on livuntries to

997/1998 fected expoe to the batimated at gion alone. as lifted in any years ofncerning RV

of a mosq

measures fry diagnostito confirm dF need to

e is a need ilable but wal infectionnd companon) should

e RVF from

diagnostic kes, which mte the use o

diseases in Areagents to During th

s at the Aiseases for rd. Followinactivities w

V is indicate

RESEARCHCS

& Nick Nwankp

zoonotic ry Animal affect livestvestock imp

Eastern RVF outbre

ort trade pan from FebUSD 109By the tim2009, Eas

f lost incomVF.

quito-borne

for RFV reqc tools for disease out

be improto develop

would be imn from vacion diagnosbe consideother patho

kits currentlmay not be of good quaAfrica” has support AUe consultaUC Headqutheir diagn

ng that Wowas prepareed in that d

REQUIRE

kpa

disease aDiseases (tock trade ports institu

Africa coeak in Kearticularly iruary 1998

9 million fome the ban st Africa hame because

virus mem

quires good the detect

tbreak. The ved for ea

p rapid pen portant for

ccinated anstics. Syndred in the dgens like B

y available able to affo

ality vaccineembarked o MS veterin

ative worksuarters in nostic activirkshop, a sed and theocument.

D TO IMPR

and one (TADs) whbetween co

uted by Midountries afenya and Sin Somalia. to May 19or the Somon animal

ad already e of prevaili

mber of the

early warntion of RVFcurrently a

arly screen side tests field testin

nimals throromic appr

developmenBrucella.

in the marord it. AU-

nes and reagon the devenary laboratshop organ2013, laboities and restrategic frae developm

ROVE

of the ich can ountries. dle East ter the Somalia, . Losses 99 were maliland imports endured ng fears

e family

ning and FV RNA, available ing and or field

g. There ugh the roach to t of new

ket pose PANVAC gents for elopment ories for

nized in oratories equested amework ent and

- 46 -

- 47 -

Session 3 Trade issues

- 48 -

ProgramScientiOIE Paris, F

was reorder specifoutbrefind th Accordcountrperiod Recomaligned It shosituativaccinin the Furtheand epis not While they apost mproper In contrade ethe reqand co

mme Officer ific and Tech

France

evised in 20to providedicities of t

eak, can nevhemselves in

dingly the rries infected.

mmendationd with these

ould be notons, under

nes for counOIE Manua

ermore, the pizootic perrecommend

the revised are, it now mortem insprly matured.

nclusion, theven in the quirements ontrol meas

OIE CODE

hnical Depart

013 and acd OIE Memhis diseasever be consn extended

revised Codd with RVFV

s for the ie three coun

ted that valining the i

ntries in theal, Chapter 2

importancriods is highded.

Chapter maalso consid

pection has .

he revised Cface of a loand mainta

ures have b

CHAPTERS

Susa

tment

The Oto enproducertifand allocaVetermeascountdescrshouthe Ppathw More

ccepted by mber Counte, mainly tidered againinter-epizoo

e Chapter dV during an

mportation ntry situatio

accination importance

e Region, m2.1.14.

e of surveihlighted. Ho

aintains thaders fresh m

been carrie

Code Chaptocalised outain a high seen implem

- 49 -

S RELEVAN

anne Münste

OIE Terrestrnhance anducts safe infication, trainspection

ates a lot rinary Servsures on thtry and Sribing the ld comply wPerformancway).

e specificallythe OIE Getries with the fact thn free of thotic periods

differentiate inter-epizo

of live anions.

is now offeof the ava

manufactured

llance usinowever, sur

at hides, skimeat and med out with

ter offers fetbreak, provstandard of mented.

NT TO RVF

ermann

rial Animal d render tran the Sectioansport, tra

on arrivaof import

vices that he side of ection 3 quality crit

with and hoce of Veter

y addressineneral Assemore flexibat countriee diseases .

es between ootic period

mals or the

ered as an ilability of d in line wi

g different veillance fo

n, wool andmeat produc

out any fin

easible optivided that Vperformanc

AND TRAD

Health Codeade in live on 5 coverinsit, quaral. In this tance to t

supervisethe export

of the Coteria that Vw they can

rinary Servi

g RVF, the mbly of Deble optionss, once thand the fac

countries/zand those

eir products

option in effective, sth the prov

approachesor virus dete

d fibre are scts as safe dings and t

ons for coueterinary Se

ce to guaran

DE

e details coanimals a

ing everythintine requicontext, t

the quality e these dting and imode is devVeterinary be evaluate

ices tool (t

Code Chapelegates in 2s to deal wey experien

ct that coun

zones free oduring an e

s are subse

each of thsafe and afvisions as de

s in inter-eection in th

safe commoprovided anthat meat h

untries to mervices comntee that pr

onditions nd their ing from rements the OIE

of the different mporting voted to Services ed using the PVS

ter 8.13 2014 in with the nced an nties can

of RVFV, epizootic

equently

he three ffordable escribed

epizootic he vector

dities as nte- and has been

maintain mply with reventive

CEO LivestoNairob

This trin 198Sudanlong-stexportexport Thus Peninsby distof thephenoexportdramarecordexportBerberSudan ConcugovernArabiaboon fregions This iauthorand sinspec

CURRENTHE

ock Trade Seri, Kenya

rade was ab83 with a bn largely esctanding civing sides wers.

from contrsula, the Hotant countrie Djibouti menal growed 3.1 milltically onces and ported 5.7 – 5ra, 1 millio

n, a total of

rrently, aninment’s legan importer,for African s’ pastoralis

s because rities of a cstaff the qctions.

NT LIVESTE MIDDLE E

WHAT

rvices, Ltd

bruptly interban on expcaped the il war and twhich were

rolling appoA / Sudaneies, principaquarantine

wth. For exaion head. Oe again. Ft data show.9 million

on head expnearly 10 m

mal welfareal and poli to halt the export trad

sts remains

of two reaonflict of inuarantines

OCK TRADEAST : THEIT MEANS

HistbeenAfriccontoil brapidsoug190deveand untipredPenSom

rrupted dueort from thbans, but ltrade deals e considere

roximately ese market ally Australi

e in 2006ample in itOnce the Soor examplewed that thead. IGADported frommillion head

e concerns ecy framewoimportation

de which hthreatened

asons : firsnterest in th

and their

- 50 -

E BETWEEE NEW RVFTO INTER-

Chip E. Stem

torically, thn partners ica and returtinued for cboom of thedly as theght more m00s, livestocelopment ofUmra pilgrl the early

dominant sinsula. By

malia alone r

e to a serieshe HoA dueivestock exbetween po

ed unfavour

85% of tshare dropia and Urug, African ts second yomali quarae in 2012,he quarant

D data for 2 Bosasso, a

d.

expressed bork, which n of livestocas placed by livestoc

st, is the phe managem

veterinaria

N THE HOF OIE CODE-REGIONAL

em

e HoA andn trade. Dhrn with spiccenturies, pe 20th cen

e oil econoeat in theirck trade furf Mecca andims. From t

1980’s thsuppliers o

the late reached num

s of import be to the feaxport from tolitical figurable terms

the livestocped to apprguay. With tlivestock eyear of operntines were, UNDP datines of Be2014 list 3and 5.2 mi

by Australiacaused Sa

ck from thisbillions of k disease.

perception oment of the ans and te

RN OF AFRE CHAPTERL TRADE

d the Arabiows would c

ces and otheerhaps mill

ntury livestoomies becar diet. In thrther expand the dramathese historhe HoA anof livestock1970s livembers of 2.5

bans by GCar of the spthere was ares on boths by livesto

ck imports roximately 1the establisxport traderation the De establisheata gathereerbera, Bos.6 million hllion head

ns resulted udi Arabia, s country. Hdollars into

on the parquarantine

echnicians

RICA AND R AND

an Peninsucarry livestoer goods. Thlennia and ock trade exame wealthhe latter handed with thatic increaseic times all d Sudan wk to the estock expo5 – 3.0 mil

CC states, bepread of rinaffected duh the importock produc

into the 15% and whment and e has expeDjibouti qu

ed, export ined from qusasso, and head exportexported fr

in a chang by far the

However, theo the hands

rt of the imes – traders often perfo

ula have ock from his trade with the xpanded

hier and lf of the he rapid e in Hajj the way

were the Arabian

ort from lion.

eginning derpest. e to the ting and

cers and

Arabian was filled

opening erienced arantine

ncreased arantine Djibouti

ted from rom Port

ge in the e largest e current s of the

mporting manage

orm the

Bl ImportfrequerejecticausinEaster Seconseriousseriousdeathsdiseaspart ofRVF inthe exthe sp The neMiddleCode athe exthe facmaintaterm im This pCode benefi

lack market t

ting authoriently experieon of the

ng outbreakrn countries

d, epizootics impact ins epidemic s. Because ose and its ocf the imporn the Terresxporters andread of dise

ew Code chae East impoare fundamporting Vetece of an ouaining openmport bans

resentation is followed,t of both sid

trade under t

ities have cence probleentire ship

ks which un.

c trans-boun some of 15 years aof the risk occurrence oters that is

strial Code rd the importease and inc

apter, if folorting countental and herinary Authutbreak ensn communic

placed by t

will highlig, then disedes.

the cover of d

commented ems with dpment or wnfortunately

undary disethe importigo in the Aof RFV in a n the exporbased on f

required updters could bcrease conf

lowed, can tries while hopefully wihorities to ruring that dcations betwthe importin

ght the chanase free tra

- 51 -

darkness. Pic

that the trdiseased liveworse, diseay has been

ases and iing countrie

Arabian Pensituation su

rting side cofear rather tdating so thbe made to idence betw

prevent theminimizing ll be the ba

restrict or adiseased livween the pang authoritie

nges to the ade betwee

cture courtes

raders oftenestock on iased animathe case i

n particulaes and theinsula whicuch as the Hould potentthan scienchat science-protect the

ween the pa

e introductiodisruptions

asis for proand control tvestock are arties, it is es can be p

Code and hn these tw

sy of Livestoc

n “cheat” amporting sls entering n several A

r RVF epizre is a stroh resulted Hajj, it has ially result ie. Further, -based decis integrity ofrties.

on of RVF ins in trade. Tactive decistrade and anot exportehoped that revented.

help to demo regions c

ck Trade Serv

nd report tships result

their counArabian and

zootics haveong memoryin over 300become an in a reactiothe old Chsions madef the trade,

nto the ArabThe changesions on thenimal move

ed. Furthermin the futu

onstrate thacan flourish

vices

hat they ing in a ntry and d Middle

e had a y of the

0 human emotive n on the apter on by both prevent

bian and es in the e side of ement in more, by ure, long

at if The for the

KSA / CSudan Kharto

Later epopula Factors(sheep animalcases r The ecat the sArabia,rumina The wain the regionsaside 4,000, Active main p(IgG). Tlocatedmonitodetectepositive

Consultant EUniversity ofum, Sudan

epidemiologictions (OR 4.2

s associated vs. goats).

s (76%), moreported abor

onomic impastatistics : 2, about 10-1ants trade to

ay the RVF oaffected reg

s to markets from the st,000).

surveillance purposes are To date no cd in high risored every 2ed in 2004 e for RVF (Ig

IMPORTING

pidemiologisf Science an

cal studies d2), high rainf

with RVF acIn humans

osquito bitesrtion storms

acts of RVF (0 million pas15 million hMakkah is es

utbreak affecgions for aboin Saudi Aratamping out

for RVF conto detect ne

clinically affsk areas (7 -3 months in Jazan &

gG) but no Ig

G COUNTR

Abdelhamid

st d Technology

The rethe So2000/identicoutbreThe afand ASeptemwhich rate wa In anigoats, epizoovaccinstage (

defined factfall (5), prox

tive virus cirrisk factors only (22%)in animals an

and the subsstoralists in head of livesstimated to b

cted the induout one year,abia, and thet of 23,829

tinues to thiew infectionsected herds in Jazan, 2 for IgM & Asir, and in M cases were

- 52 -

Y PERSPEC

d Ahmed Moh

y

egion affecteouth West of/2001 outbcal to those eaks started ffected areas Asir (27% mber 2000.683 (83%)

as 14%.

mals, the in1.3% in ca

otic, the conation, follow(using live –a

ors associateximity of lake

rculation werwere identif, animals onnd 51% repo

sequent bansEast Africa astock are exbe worth USD

ustry in KSA, the 4-year e 4-year long9 smuggled

is day and iss (IgM) or cwere diagnoin Asir, 1

IgG. Throug 2006 in Jae diagnosed,

CTIVE : SA

ohamed Elfad

d most by thf the Kingdoreaks, the identified in in August 20were mostlyof cases) Across all were labora

nfection ratemels and 1.trol measure

wed by partiaattenuated va

ed with RVFs and ponds

re a high IgMfied as exposnly (1%). Sixorted out-of-t

s) on trade aare highly relxported to SD 600 – 900

A was throughlong ban of

g ban on imp small rum

s conducted linical diseasosed. In addin Makkah ah these ani

azan. In 201 nor clinical

UDI ARAB

dil

he consecutiom of Saudi

viruses isoAfrica (199

000 and last situated in Jwith most regions 88

atory-confirm

e was 9.7%2% in cattlees were largl and ring vaaccine).

F in the KSA(4.2) and lu

M level, abortsure to bothty-two (62) %the ordinary a

re easily undiant on sales

Saudi Arabia 0 million per

h the closureanimal mov

portation of minants to M

annually in tse and to moition, elevenand 1 in Almals, RVF v4, 10 out ofcases.

IA

ive RVF outbArabia (KSAolated were0/91, 1997/ted until ApJazan (66% cases occu

86 were repmed. The cas

% in sheep, e. At the tim

gely based oaccinations a

A as dense ush vegetatio

tion and the h mosquito b% of affecteanimal death

derstood whes of livestock annually, tannum.

e of livestockvement from livestock fromMakkah (wo

the rainy seaonitor herd i

n sentinel hebaha) and tvirus circulaf 213 anima

breaks, is A). In the e almost /98). The ril 2001. of cases)

urring in orted, of e fatality

7.9% in me of the n (mass) at a later

mosquito n (2).

genotype bites and d human

hs

n looking to Saudi he small

k markets affected

m Africa, rth USD

ason. The immunity erds were these are ation was als tested

- 53 -

Session 4 Prevention, biothreat

and early warning

- 54 -

CoordinInter-afAU Nairob

RVF esurveillactivitymonitoconsistmethodareas ((Kenyaand mabe sens FurtherSurveilenvironmeteordata aeffectivcountriSOPs trapid cCode. Howeveactivityas desproducanalyticplan haaiming

nator of the Sfrican Burea

i, Kenya

epizootics uslance systemy. During inor RVFV activtent with thed applied in t(Ethiopia, K

a, Uganda). Aapping of presitive enough

rmore, RVF slance is u

nmental pherological agend informatveness of suies of the regthat should bcontainment

er, surveillany to identify acribed unde

cts. Furthermcal study thaas been final at developin

SU

STSD projectu for Animal

sing historicms in place ter-epizootic vity in high e recommenthis case is renya, and SAs identificaevious epizooh to capture a

surveillance ssually heighenomenon pncies and otion as RVF

urveillance sygion have debe complied of the diseas

nce systems areas with lower chapter 8more, the iden

at combines ized to unde

ng risk maps

URVEILLAN

Zt Resources

ThpoaffThepthesiganexp Tain tarregrapmaact

cal data on largely focuperiods, ta

risk areas thdations of crandom selecSudan) or frotion of high otics, targeteall future out

systems are lhtened and particularly ther responsearly warni

ystems. In peveloped emewith in orderse, which is

in most counw and high v.13 of the Cntification andisease data

ertake a crossusing analyt

- 55 -

NCE SYSTE

Zelalem Tade

e IGAD regpulation in fected by thee HoA regionizootics as eve past decgnificantly afimals and hport of anima

king lessons the IGAD re

rgeting RVF. gion aims at pid responseaybe caused tivities, most geographics on detect

argeted survehrough detecchapter 8.13ction of indivom sentinel risk areas is

ed surveillanctbreaks.

linked with m triggered predictions ible regionalng mechani

preparedness ergency prepr to determinalso consiste

ntries don’t vector densitiCode, could nd designatioa as well as s-sectional sttical methods

EMS IN PLA

esse

gion is endoAfrica. Howe impacts ofn is a global videnced by

cades. Occuffected the humans as wals and anim

from past eegion have pThe main obearly detectie and curbby the dise

t countries hcal distributiion of the peillance is uction of RVF3 of the OIEviduals from s

herds estabs largely infoce based on

meteorologicawhen forecof excessi

l agencies. Tsm apparenfor an unfo

aredness plane the extentent with the

usually involies. Such inffacilitate sa

on of high risinformation

tudy of RVF s and tools.

ACE

owed with thever, the regf animal disehotspot for trecurrent warrence of region by cawell as sustaal products.

xperiences, mput in place bjective of RVon of epizoot

b subsequenease. To guihave identifieion of prevpathogen andundertaken iF antibodies,E Terrestrial susceptible rblished to mormed by thesuch descrip

al alert systemcasts of favive rainfall The applicatitly enhances

ortunate evenans that spelt of the outbrprovisions of

ve vectors, wormation on afe trade of sk areas shou

on risk factincluding its

he highest gion is alsoeases includhe emergenc

aves of outbreRVF epizooausing mortained restric

most of the surveillance

VF surveillantics in order nt devastatiide their sured high risk ious outbread evidences in most cou, which is aCode. The

ruminants in monitor RVFVe geographicptive analysis

ms in most cvourable/pred

are receivion of meteos the efficient of RVF epl out the surreak for effef chapter 8.1

which is an iRVF vector aruminants a

uld be informtors. In this s potential ris

ruminant severely

ding RVF. ce of RVF eaks over

otics has alities of ctions on

countries e systems ce in the to trigger ons that rveillance areas for aks. The of RVFV

untries to practice

sampling high risk

V activity cal extent s may not

countries. disposing ed from orological ency and pizootics, rveillance ctive and 13 of the

mportant activities, and their

med by an regard, a sk factors

BRID

ProgramOIE – WOIE Brusse

the intand th The usanimato impobtaingovernnationIHR (2synergPVS Pidentifand ststrateghas beOIE an In his campalargelyillustraOne H

DGING WHO

mme Officer WHO Liaison

ls, Belgium

ternational he Internatio

se of thesel health sysprove their ed and are

nance systeal capacitie

2005). OIE gies betweePathway natfy strengthstrategic invegies targetineen tested ind WHO.

presentatioaigns to desy inspired tate the appealth appro

O AND OIE

standards donal Health

e normative stems in a coordinatioin line with

ems, the Oes and analyand WHO hn the frametional bridgs and weakestments. Png capacity n pilot coun

on, the spescribe the prthe developproach whicoach, while

TOOLS FO

Stép

EzoRcoansutocleawWmrewth

described inh Regulations

frameworkconstructiven. Stemmin

h good goverIE and WHyse gaps in have also coeworks and ging workshknesses andParticipation

building atntries and w

eaker will usrocess and ment of thh finally coaccelerating

- 56 -

R THE ASS

phane de la R

xperience oonotic infeift Valley onfirmed tnimal healtuch events.o be robustlose partnerarly detect

whilst respeWHO are mandated tespectively,

with strengtheir complian OIE’s Terr

ns (IHR, 200

ks has provie and o peng from thrnance prin

HO have detheir comp

onducted an tools used

hops offer ad accordingn in these wt the humawill be inclu

se his expepotential ouis approach

ontributes tog progress t

SESSMENT

Rocque

gathered fectious disfever outbhat collaboh systems i Human ant, have suffrship to addtion, assesecting inter

the inteo improve on a globa

thening theance underrestrial and 05).

ided opporterations-orieis, significaciples. To seveloped copliance to On in-depth a

d in the twoa structuregly define cworkshops han-animal huded in futu

erience fromutputs. Thesh and conco globally powards Glob

T OF NATIO

from emereases, inclreaks fromoration bets crucial to d animal hficient capadress commssment andnational st

ergovernmenanimal a

al scale; their capaciti the normaAquatic An

unities to eented dialogant results support counomplementaIE internatianalysis of to sectors. Jd approachconcerted chelps countrealth interfure program

m RVF outbse RVF outbrete case s

promoting tbal Health S

ONAL CAPA

rgencies ofuding the

m 2006 totween hum effectively ealth systemacities and on issues red rapid retandards. Ontal organand humanhey assist cies and imative framewnimal Healt

engage humgue, explorihave been ntries improary tools toional standathe differen

Joint WHO h to help ccorrective mries define face. This a

mmes undert

breaks manabreaks have studies are he importanSecurity.

CITIES

f major wave of

o 2010, man and

manage ms need work in

egarding esponse, OIE and nizations health

countries mproving works of th Codes

man and ng ways recently

ove their o assess ards and nces and IHR/OIE

countries measures national

approach taken by

agement actually used to

nce of a

VeterinMinistrZoonotNairob

Governsystemresponestablof occepidemto enserviceand effectidiseason anIn thedecisiohave bRVF epidemoutbrethat inin eac Kenya

nary Epidemiory of Agricultic Disease Ui, Kenya

nment and matic plan nse to outbished to ascurrence of mic before able nationes to antic

react prvely to

se’s devastimal and he contingenon points been identifoutbreak

mic, eak and recnform actionh phase.

a RVF risk m

CONTI

ologist ure, Livestocnit

partners pinvests in

breaks of Rssess the ra major Rit arrives anal veterinipate the rromptly aprevent t

tating imphuman healncy plan, k

and actiofied within tcycle (intpre-outbre

covery phasns to be tak

map. ZDU, Ke

INGENCY P

ck and Fisher

RVsiEaw10inUimepofm Sihaan

prepare for ensuring c

RVF in the risk RVF and ary risk and the act lth. key ons the ter-ak,

ses) ken

enya

- 57 -

PLANNING

Austine Bite

ries

VF is a mgnificant gast Africa, Rith prolonge0 years. In

nduced estimSD 24.5 m

mpacts on pisodic natuf outbreak

mitigation an

ince 2008,ave developnd control. and respo

capacity ancountry. A

FOR RVF :

ek

osquito-borlobal threatRVF usuallyed inter-epin Kenya, thmated lossemillion, baseboth agricuure of the dks create nd control.

the Goverped a Contin

The Continnd to Rift d focuses A RVF earl

KENYA

ne viral dist to human occurs as edemic periohe 2006/20es to the ecoed on the oulture and isease and special c

nment of Kngency Plan gency Plan Valley Fev

on early dey warning

sease that s and livesexplosive epods of betwe007 RVF oonomy of moutbreaks’ other sectothe rapid e

challenges

Kenya and for RVF pre describes

ver outbreaetection ansystem hav

poses a stock. In pizootics een 8 to outbreak ore than negative ors. The evolution

for its

partners evention how the ks. This nd rapid ve been

ScientiFood SInternaILRI Nairob

risk an The frwith aperiodmosqusub-phare obepidemawarenprevenmobiliassessmakersexperieOne Hsectors For thaddresmodalpredetincludOfficerintegra

D

ist Safety and Zoational Livest

i, Kenya

nd in makin

ramework bppropriate a, (ii) pre-ou

uito swarmshases), (iv) bserved, andmic stages ness, nationtion, case sation, esta

sment. The s to ensure enced durin

Health princs at each de

he framewossed: (i) a ities put intermined cing a clears to field oate the fram

DECISION –

oonosis tock Researc

g decisions

reaks the Ractions. Theutbreak pers), (iii) outbrecovery ph

d (v) post-ouare: capaci

onal and manageme

ablishing ordevelopmeownership

ng previous ciples by secision poin

ork to be enational RV

n place to riteria, (ii) r chain of officers and

mework in th

– SUPPORT

h Institute

f

t

to control t

RVF epidemese steps idriod (classifbreak periodhase includutbreak recty building regional cent, regulatr strengthenent of the fand relevanRVF outbre

pecifying innt.

effectively VF emergenenable the an effectcommand

d communitheir designs

- 58 -

T FRAMEW

Bernard Bet

In the easteirregular cyagents to iface of aprediction time given drivers andRVF Decisiodeveloped decision-maconsideringcan paralysmeasures. instance cain the regiothe disease.

mic cycle indentified in fied into ead (classifieding a 45-daovery and rand trainin

oordinationtion of traning instituframework hnce to the deaks. The fnterventions

operationalncy fund ha

fund to bive commu and feedties, and (i

s.

ORK FOR E

ett

ern Africa reycles that mimplement n outbreaksystems dothat there

d processes on Support

to guideaking in tg that uncese the dep

The last aused subston due to b.

nto five expthe framew

arly warningd into suspeay period wreflection. Ing, commu, early wade and ma

utions and has involveecision-makramework hs for both

ized, threeas been este made avunication sback from ii) that app

EAST AFRIC

egion, RVF make it diffeffective in

k. Furthermo not offer

is inadequthat promFramework

e timely, the controertainties oloyment of

(2006/20antial socio

by delays in

plicit steps work includeg, localised ected and chen no furtnterventionsnication, adarning, surarkets for policies, and multiple king challenhas also beeveterinary

key issuetablished aailable rapi

system has the Chief

proved RVF

CA

epidemics ficult for mnterventionsmore, the

an adequauate knowlote outbrea has therefoevidenced

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007) outbro-economic n the recogn

and matche: (i) inter-e rain, floodconfirmed other livestocs matched dvocacy andrveillance, livestock,

nd risk andpartners, d

nges that haen aligned and human

es will havnd proceduidly in resp been estaVeterinary/Contingenc

occur in itigation s in the existing

ate lead edge on aks. The ore been

based disease making

response eak for impacts

nition of

es them epidemic ding and outbreak ck cases to these d public disease

resource d impact decision-ave been with the n health

e to be ures and ponse to ablished /Medical cy Plans

ResearGESTAGoddarNASA Greenb

indicatmonth The Rhowevmappeof RV( http:partnerisk. Sand chclear aor SSTresultenormaRift Vathe sea The imregionhigherseasonon ale

RVF

ch Scientist AR/USRA & Brd Space Flig

belt, MD, Un

ting about h values of t

RVF risk maer in Octobed to be areVF vectors.://www.ars.uers (OIE, FASome of theholera in seand strong cTs in the eed in a poorl rainfall bealley fever aason.

mmediate fal epizooticr probabilityns. It is advrt and prepa

PREDICTIO

Biospheric Scght Center

ited States

60-65% to he Niño 3.4

apping modber – Noveme potential r A series usda.gov/BuAO and WHOese areas ineveral locatcoupling beeastern equar and aborteelt remainedactivity pers

future seasoc, restockiny of a medisable thereare for early

ON AND RI

A

ciences Labo

Rasrwe

IAPiwife

peak at we4 index betw

del did not mber some risk - where

of advisousiness/docsO) advising en Sudan repions in El G

etween the aatorial Pacied rainfall sed in the nortsisted in Su

ons portendng of livestium (+1.5)efore for all y surveillanc

- 59 -

ISK MAPPI

Assaf Anyam

oratory

RVF outbreanomalouslystudies indrainfall in with warm events.

In June 2AtmosphericPrediction Cndicating awarm ENSOndex: betwfall. Howeveevent, a reveak strengthween +0.5°

identify ancontiguous

e ecologicalories were s.htm?docidenhanced vported outbGezira stateatmosphere ific Ocean eason in larthern half oudan and S

ds elevatedtock after t to strong national an

ce.

NG : 2014

mba

eaks are ky high rainicate that equatorial El Niño

014, the c AdminisCenter issuea 70 % chaO event in

ween 1.0°C er given thevised forecah during theC and +0.9

ny areas ats areas in S conditions posted on

d=23461 ) vector survereaks of un

e (http://wwand the wa

and weak wrge parts of of the regionSouth Sudan

risk due tthe 2010-2(+2.0) El N

nd regional e

4-2015 SEA

known to nfall in Eaperiods of eastern AfrSouthern O

National Oistration’s ed a consenance for the the late and 1.4°C

e delayed dast was issue late fall a°C).

potential South Sudawould supp

n the RVFand sharedillance in ar

ndiagnosed w.promedmarm Sea Suwarming in East Africa

n and areas n throughou

to lapsed t2011 drougNino event early warnin

ASON.

follow perastern Afrisuch aboverica are asOscillation

Oceanograp(NOAA)

nsus model e developmsummer (N

C) and 80%developmenued early inand early w

risk in Sepan and Sudport the emF Monitor d with interreas shown haemorrhag

mail.org/). Larface Tempthe Indian

a. Overall, that potentia

ut the rema

time since ght period during the

ng institutio

riods of ca Past e-normal sociated (ENSO)

phic and Climate forecast ent of a

Niño-3.4 % in the nt of the the fall inter (3-

ptember, an were

mergence website

rnational to be at

gic fever ack of a

peratures n Ocean, he above l risk for

ainder of

the last and the coming

ons to be

AnimalAGAH FAO Rome,

Given activityin theSudanFederaof KeTanzanthese c

a)

b)

c)

down

l Health Offic

Italy

the predicty based on identified

n, the Repual Republic enya and tnia, FAO, Wcountries to

Heighten for RVF iat-risk areIncrease preparedntargeted vrisk areas;Raise awawith comemergenceanimals fi

The EMnloaded from

TH

cer

ted risk forn abnormall

areas of thublic of Sou

of Somaliathe United

WHO and Oo:

their level n human a

eas; their

ness, andvaccination ; areness andmmunities e of therst and late

MPRES Watch www.fao.org

E JOINT EA

Dani

IpEcadicpd(apam

potential Rly high rainhe Republicuth Sudan, a, the Repud RepublicOIE encoura

of surveillaand animals

level d implem

in known

d communicthe risk

e disease er in humans

h Bulletin cang/3/a-i4295e

- 60 -

ARLY WARN

iel Beltrand-A

In Decembpersistent aEast Africa.countries availability data, such indices, proconditions tpopulation developmen(EWSs) for vaim of suchpossible incand providmitigation.

RVF nfall c of the blic

c of aged

ance s in

of ment

at-

cate of in

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an be e.pdf

NING RELE

Acrudo

ber 2014,above-averag In responsto remain of near-reaas rainfall

ovides an othat are lin

dynamics.nt of cost-efvector-borneh EWSs is tocrease in vee informat

EASE

climate ge rains andse, FAO, OIE

vigilant al time sate, temperatupportunity tked to vect This ha

ffective Earle diseases, o monitor thector abundion for pr

models pd risk of floE and WHOabout RV

ellite-based ure and veto monitor tor abundaas facilitatrly Warning including Rhe first signdance and Rrevention a

predicted oding in

O warned VF. The

climate egetation climatic nce and ted the Systems

RVF. The nals of a RVF risk and risk

- 61 -

Session 5 Regional

coordination

- 62 -

ProgramScientiOIE Paris, F

requesthe cojustific

Requefinalisbeen dand prnumbescheduarea co

The be

Quality

mme Officer ific and Tech

France

sted numbeonfirmation cation of the

ests are proced with vacdelivered to rogress repoer of vaccinule implemovered, and

enefits for M

y

Vaccininterna

Vaccinreques

Importformul

The vinot ex

hnical Depart

er of doses athat appro

e request, b

cessed by tccine supplthe country

orts, includines eventuaented (vacc

d possible in

Member Cou

nes supplieational stan

nes are dest/availabilit

tant reductlated vaccin

rtual stock pire before

OIE

Susa

tment

The eirrespefollowfor tenegotiof an produ(f) thintern

Once banksDelegafrom O

and timefraopriate coldbased on the

he OIE Heaiers and thy, the OIE Ding informatally used, tcination of nformation o

untries of th

ed to coundards;

elivered wty of the cou

tion in thene in sub-op

/ replenishmbeing used;

- 63 -

VACCINE B

anne Münste

establishmeective of

wing steps :ender, (b) iation and sinitial stocction of vahe supply/

national airp

establisheds by submate, to the OIE regionaame of delivd chain infre disease si

adquarters aen provided

Delegate is rtion on the the numberwhich spec

on post-vacc

he OIE are n

ntries are

with the reuntry;

e risks assoptimal cond

ment mecha;

BANKS

ermann

nt of a glothe diseas(a) the pubthe selec

signature ofk of vaccine

accines upo/delivery o

ports.

d, countrieitting an oOIE Direc

al offices. A very has therastructure tuation in t

and flight ded to the corequested tovaccination

r of animalcies, age grcination mo

numerous :

of high qu

equired fle

ociated wititions;

anism ensu

obal or regiose targetedlication of a

ction of su a contract,es, (e) the n request f

of the vac

es can accofficial reqtor Generalvaccine req

en to be subis present.he country

etails and suntry. Aftero provide thn campaign s vaccinateroup, etc…onitoring.

uality and

exibility an

h storing l

res that pro

onal vaccind, will enan internatioupplier(s), , (d) the propurchase orfrom countccines to

cess these quest, by tl, with the quest form bmitted, alo It also req

shipping docr the vaccinhe OIE with period (dated, the vac), the geog

comply w

nd based

large quan

oduced vacc

ne bank, tail the onal call (c) the

oduction rder and ries and

agreed

vaccine the OIE support with the ong with quires a

cuments nes have updates tes), the

ccination graphical

with OIE

on the

tities of

cines do

- 64 -

Logistics

• Timely dispatch of emergency stocks in line with field needs;

• Possible delivery of relatively small or large quantity of vaccines;

• Limits possible costs associated with the multiplication of local registration and vaccine purchases;

• The burden of storage lies with the selected vaccine supplier(s), rather than with the purchasing countries or international organisations;

Cost effectiveness

• Economies of scale - a cost reduction per vaccine unit or dose;

• Financial mechanisms allowing direct purchase by countries (OIE as sole supplier);

Improved coordination

• Harmonisation and coordination of regional control programmes or the implementation of global / regional control strategies;

• Support for multi-party vaccination campaigns (e.g. public-private partnerships and NGOs)

To date, OIE has established several vaccine banks across the world. The vaccine bank for avian influenza is funded through a multi-donor approach* involving the European Union, Canada, and the UK, for a total of 62 million AI vaccines delivered (as per April 1st, 2015), mostly to Egypt and Vietnam. The OIE Rabies Regional Vaccine Bank has so far supplied 3.7 million doses to Asian countries and 3.2 to other countries, including several African countries (Mali, South Africa, Togo). The OIE Regional Vaccine Bank for PPR in Africa has supplied vaccines to the pilot control areas of Ghana and Burkina Faso mostly, but also to Mali and Togo, for a total of 14 million doses. Finally the OIE Regional Vaccine Bank for FMD in Asia, has delivered some 3 million doses in 5 Asian countries

This proven track record raises the question : is there scope and justification for an OIE regional vaccine bank for RVF in (Eastern) Africa and the Middle East ?

RegionECTADFAO Nairob

the SeCommand paoverall The Gincludactivitinformdiseas(iv) imsupporlaborat(vi) enand (vprivate The Pl The GOuaga

a)

al Manager D Eastern Afr

i, Kenya

ecretariat is mission for A

artners attel guidance a

GF-TADs foing (i) facies; (ii)

mation/data se preventiomproving drting the etories, refer

nsuring the vii) develope veterinaria

lan focuses

GF-TADs Afdougou ado

The GF-TAcountries,diseases:

ica

provided bAfrica and reend the RSCand supervis

or Africa’s cilitating reimproving on priority

on, surveilladiagnostic lestablishmerence laboraappropriateing allianceans and live

on 7 priorit

frica 9thStopted differe

ADs for Afric AU-IBAR, FMD, PPR,

GF-

TTinthdinatsucon Ta It(R

y the OIE RepresentativC annual msion of the

5-year Acegional and

national animal dis

ance, early laboratory nt/reinforceatories; (v) e advocacy es and fosteestock profes

ty diseases:

teering Coment recomm

ca Action pFAO, OIE, CBPP, ASF

- 65 -

-TADS – AF

Bouna Diop

The Global Transboundan 2004 is ahe preventi

diseases (TAn the past st country lustainable oordinated ational fram

The GF-TADsview to res

t is governRSC) chaireRepresentatves from the

meetings. ThGF-TADs G

ction Plan d cross-borand regioeases; (iii) detection, capacity a

ement of nsupporting for animal er collaborassional orga

PPR, FMD

mmittee mmendations i

lan be comRECs and

F and RVF;

FRICA

p

Framework ary Animal joint initiaton and con

ADs). The inshowing thaevel is notunless th

regional apmeworks.

s for Africa pond to prio

ned by a Red by FAO ion for Africe Regional Ehe GF-TADslobal Steeri

2012-201rder collaboonal knowproviding tnotificationnd performational andthe reinforcdisease pre

ation betweanisations.

, RVF, rabie

meeting heldincluding:

pleted with other relev

for the ProDiseases (Gtive of OIE antrol of traitiative is b

at progress t likely to he efforts pproach/emb

was establority diseaseRegional Swith AU-I

ca. CVOs, mEconomic C

for Africa ng Committ

6 target doration, incledge andtechnical gu and rapid

mance at nd regional vcement of Vevention anden public V

es, ASF, ND

d on 8 –

baseline sivant partner

ogressive CoGF-TADs), laand FAO to

ansboundarybuilt on expin controllinbe success

are partbedded into

ished in 20es of the co

Steering CoBAR as vic

members of Communities

operates untee.

different obcluding netd sharing uidance to response snational levaccine proVeterinary Sd control acVeterinary S

D and CBPP

9 July 2

tuation provrs for the f

Control of aunched achieve

y animal eriences ng TADs sful and t of a o supra-

006 with ontinent. ommittee ce-chair; the OIE

s (RECs) nder the

bjectives tworking

quality improve

systems; vel and oduction Services; ctivities; Services,

P.

2014 in

vided by following

- 66 -

b) The Secretariat of the ALive Executive Committee, supported by key partners of GF-

TADs for Africa, ensure a proper advocacy at the highest authority to promote ownership of the GF-TADs for Africa mechanism and its 5 year Action Plan by the RECs and Members Countries;

c) African countries be encouraged to continue their progression in the OIE PVS

Pathway, especially by requesting, when relevant, PVS Evaluation Follow-up mission and taking ownership of the outcomes in order to improve the good governance of their Veterinary Services and to ease access to funding both internally and externally using round tables with donors.

Under the GF-TADs for Africa aegis, different initiatives have been taking place including the preparation of the ASF regional strategy, the Progressive Control Pathway for FMD (PCP-FMD) Roadmap meetings, as well as the RVF conference in Djibouti.

RepresRegionOIE Beirut,

The sp

a) b) c)

d)

Actionsuch ameetinthese strateg Among • f

i• a

s The neCommin Nov

sentative al Represent

Lebanon

pecific objec

promotprovidefoster Organisand, toepidem

ns conducteas FMD, PPngs to discudiseases, i

gies.

g others, the

facilitate coin the regioand promotstandards th

ext RSC memission for thvember 201

tation for the

ctives of thi

e the controe strategic dcooperation

sations and ogether wit

miological ev

d by the GFPR, RVF anuss and agincluding t

e RSC will c

ollaboration n; te adequathrough capa

eeting will he Middle E5.

GF-TAD

e Middle East

TgAtar2iaeMS

s 5 years ac

ol and eradidirection to tn between the Regiona

th the Secvents and co

F TADs RSCnd lumpy skree on comhe assessm

continue to:

and maxim

e governanacity buildin

be held in East, to be

- 67 -

DS – MIDD

Ghazi Yehia

t

The previougathered inAmman (Jorto raise a aspects of reference o2012-2016information activities establishingMiddle EastSecretariat.

ction plan a

ication of spthe Secretamember c

nal Support cretariat, toontrol effort

C addressedkin disease

mmon procement of nat

:

mize synergi

ce of Veteng programm

the marginheld in Doh

LE EAST

ia

us GF-TAD Dubaï (UArdan) in Sepregional cthe GF-T

of a regiona6 aiming

and data related to

g a reportint activities,

are to:

pecific TADriat; countries, Units; o ensure gts.

d priority di, through adures for ttional plans

es among t

erinary Servmes at natio

s of the 13ha, Qatar or

Ds RSC forAE) in April ptember 22onsensus o

TADs and al action pin particufor monit

o the prig mechanislinked to t

s in the reg

donors, Re

uidance fo

seases prevassistance the surveillas and elab

the countrie

vices in acconal and reg

3th Conferento be held

r the Midd 26, 2012

2, 2013, suon the govon the te

plan for theular at getoring the iority TADsm of the Gthe Global G

gion;

egional Spe

r field, lab

vailing in thto organise ance and coboration of

es and stak

cordance wgional levels

nce of the Rin Beirut, L

dle East , and in cceeded vernance erms of e period enerating

regional Ds; and GF-TADs GF-TADs

ecialized

boratory,

e region regional

ontrol of regional

eholders

with OIE s.

Regional Lebanon

AFRI

(*) CooInter-afAU Nairob

TADs w To impIBAR cinformaSystemequipm To enhof RVF AU-IBAStandaUSAID preventother Tcapacitas protstatus trainedof SMPfrom tproducparticippolicy acoordinand wicommo

CAN UNIO

ordinator of tfrican Burea

i, Kenya

within the fra

prove informcompiles andation system

m (ARIS) in tment.

ance knowleoutbreaks, c

AR and the Iard Methods are supportion and conTADs is basty building fotocols for theand welfare

d on sanitary Ps for exportthe HoA haction laboratopation of AUand regulatonation, commth importing

odity associat

N INTE

James S

he SMP-AH u for Animal

amework of L

ation sharingd disseminatems is being pthe AU MS t

edge on the ecross-section

IGAD Centre and Proced

rting regionantrol in the sed on the or laboratory e prevention ae of livestock

processes at quarantine s also beenories is also

U MS in animry environme

munication ag countries ition, the Nor

R-AFRICAN

Wabacha*, ZSamuel Wakh

Project Resources

The specIts mdevenutriprosp LivespeopRVFVprodu To aAfricappro(LiDethe l

LiDeSA.

g among thees informatioprovided throhrough train

epidemiologyal surveys fo

e for Pastoraldures in Animal coordinatHoA. The coStandard Metesting, surv

and control ok for export

and certificatstations. Te

n enhanced being streng

mal health stent for the dend information the Middlerth Eastern A

- 68 -

N BUREAU

Zelalem Tadehusama & Ah

Interafricanialized technmandate is lopment andtion and foodperity of the

stock contribple and to thV pose a mauctivity and a

address the a, the AUoved the LeSA) as a lolivestock sec

e MS and Ron on the sanough the rollings and the

y of RVF to aor RVF are be

l Areas and mal Health (Sion and haroordination a

Methods and veillance andof RVF in line, veterinary tion. Supportechnical and

through tragthened andtandard settielivery of veton sharing oe East, AU-

Africa Livesto

FOR ANIM

esse, Henry Whmed El-Sawa

Bureau for Anical office oto support

d utilization d security anpeople in the

butes significheir nationaajor challengaccess to live

challenges Heads of S

Livestock Deong-term framctor. AU-IBA

Regional Econitary status.ing out of th

e provision of

aid decision meing undertak

Livestock DeSMP-AH) prormonization and harmonizProcedures

d disease cone with OIE stpersonnel in

t has also bemanagerial

ainings. The AU-IBAR isng processeserinary servic

on livestock tIBAR and ICck Council o

MAL RESOU

Wamwayi, alhy

Animal Resoof the Africanand coordinof animal r

nd contributee MS of the A

antly to the l economies e due to theestock marke

facing the tates and G

Development mework for tAR is addres

onomic Comm Further suphe Animal Rf information

making on pken in IGAD M

evelopment (oject with fiof animal d

zation of the(SMPs) app

ntrol and thetandards. To n quarantineeen providedcapacity for capacity o

s coordinatins. The develoces is also surade among

CPALD are sr NEALCO.

URCES (AU

ources (AU-IBn Union Comnate the suresources to e to the wellbAfrican Unio

livelihoods obut TADs

e negative eets.

livestock seGovernments

Strategy fothe transformssing RVF a

munities (REpport to animResources Infn and comm

prevention anMS.

(ICPALD) thrnancial suppdisease surve control of proach. This e application guarantee the stations ha for the deve

r veterinary pof veterinaryng and promopment of reupported. To countries inupporting a

-IBAR)

BAR) is a mmission. stainable enhance

being and on (AU).

f Africa’s including ffects on

ectors in recently

or Africa mation of and other

ECs), AU-mal health formation unication

d control

rough the port from veillance, RVF and involves of SMPs

he health ave been elopment personnel y vaccine oting the esponsive enhance the HoA livestock

Head, Centre IGAD Nairob

traders ICPALand Prin IGA The mcontro Under joint eand vstreamlaboratsurveil With tGuidelCertifiand AHlessonanimaand mwas dethrougimprovPPR aControguidanlessonRVF an

INTE

Livestock Profor Pastoral

i, Kenya

s.

LD and AU-Procedures inAD MS (STS

main progresol is summar

SMP-AH nefforts to coalidated wi

mlining of ttory technicllance, insp

the supporelines for Livication (AHCHC forum hs in the arel diseases s

motor bikes. eveloped. A gh the Animve disease rand other smol Coordinance on dev. The samend other TA

R-GOVERN

ogramme Areas and Li

IBAR have n Animal HeD) and mob

s of the tworized below

ine priority ontrol TADs ith MS andhe SMP incians and exection, cert

t of the Sivestock IdeC) Systems has also beeea. MSs wersurveillanceRFV is oneregional co

mal health nereporting. Tmall ruminaation Commelopment oe regional CADs.

MENTAL A

A

ivestock Deve

The Ina RECKenya,livestoruminaproducMiddlecountrGulf acoverinthe mereasoncapacialso ewhich

been able tHealth (SMP-bilize resour

o regional p:

TADs were and RVF is

d developmto the natixport quaratification, d

STSD projecentification and validat

en establishre also suppe through pee of the fouoordination etworks to ehe regional

ant diseasesmittee embrof national Coordination

- 69 -

AUTHORITY

Ameha Sebsi

elopment

ntergovernm covering e, Somalia, ck resourceants. The cts in the ree East counies and adare also oppng about 50eat required hamperingty to contr

export bans affected h

to develop -AH,) and Irces from U

projects and

identified ts one of th

ment partneonal develo

antine workeiagnostic te

ct, ICPALDand Tracea

ted by MS ahed to providported to imersonnel traur diseases mechanismenhance excframework

s were also racing MS strategies

n Committee

Y ON DEVE

sibe

mental Authoeight countr

South Sudes are esti

demand egion, in othtries is highaptation to tportunities. 0% of live d annually bg the growtrol trans-bo

on East Aheavily the

two projectImproving SSAID and E

support to

together witem. An SMers; the proopment proers were alsechniques a

D and AU-Iability Systeand developde guidance

mprove their aining for lafor which a

m on diseasechange of lefor progresdeveloped has also

and facilitae will also

LOPMENT

ority on Devies: Djibout

dan, Sudan mated at afor livesto

her regions wh. Proximitythe taste ofHowever, sanimal and

by the Middth of markeoundary disAfrican cou

livelihood

t proposals; Surveillance EU respectiv

MS with sp

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- 70 -

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- 71 -

Session Poster session

- 72 -

- 73 -

COMPARATIVE GENOME SEQUENCE ANALYSIS OF RVF VIRUS ISOLATES FROM 2008 TO 2010 OUTBREAKS IN SOUTH AFRICA

Moabi Rachel Maluleke, M. Phosiwa, Baratang Alison Lubisi, G. Michuki a,

P.S Kegakilwe b, S.J Kemp a,c & P.A.O Majiwa d Onderstepoort Veterinary Institute ARC-OVI Pretoria, South Africa a. International Livestock Research Institute, Nairobi, Kenya b. Veterinary Services, Northern Cape Province, South Africa c. School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom d. Department of Veterinary Tropical Diseases, University of Pretoria, South Africa RVF is a zoonotic disease. Since the 1930s when it was first noticed in Kenya, the disease has appeared in other African countries and in the Arabian Peninsula. The disease affects both humans and animals, causing major losses in livestock and negative impact on the livelihoods of people who depend on them. Because of its zoonotic nature, RVF is recognized as a disease which is a threat to all who live in countries where its mosquito vector thrives. Because of the changing weather patterns, it is essential to institute and sustain in-country bio-surveillance of this disease using the best tools available, to stop potential outbreaks at source or effectively manage them if they were to occur. Outbreaks of RVF usually follow weather conditions which favour increase in mosquito populations. Such outbreaks are normally cyclical, occurring once every 30 or so years. However, this is not always the case. For example, recent outbreaks of the disease in South Africa have occurred with increasing frequency and rather unexpectedly: in 2008 (in Mpumalanga, Limpopo and Gauteng), in 2009 (KwaZulu-Natal, Mpumalanga and Northern Cape provinces) and in 2010 (Eastern Cape, Northern Cape, Western Cape, North West, Free State and Mpumalanga). As of August 2010, there were 232 human cases, with 26 confirmed human deaths. In order to obtain comprehensive background information on the genetic composition of the RVF viruses circulating in South Africa, genome sequence analyses WERE undertaken on RVF viruses isolated from samples collected over time from animals at discrete foci of the outbreaks. The oldest isolate whose genome was analysed is from a 1955 case and the most recent one from a case in the 2010 outbreak. Complete sequences have been obtained from 20 different isolates so far. We report on, and discuss, phylogenetic relationships among the isolates as reflected by their genome sequences, and implicit recombination among genes encoding glycoproteins Gc and Gn, which have a role in host protective humoral immune responses. Agricultural Research Council Onderstepoort Veterinary Institute, No. 100 Old Soutpan Road, Private Bag X05, Onderstepoort 0110 Gauteng, South Africa [email protected]

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SEROPREVALENCE OF RIFT VALLEY FEVER ANTIBODIES IN SOUTH AFRICAN SUIDS

Baratang Alison Lubisi, P. Ndouvhada, T.V. Mareledwane, T. Tshabalala,

V. Mangwale, M-L Penrith a & A.D.S Bastos c Onderstepoort Veterinary Institute ARC-OVI Pretoria, South Africa a. Department of Veterinary Tropical Diseases, University of Pretoria, Onderstepoort, South Africa b. Mammal Research Institute, Dept of Zoology and Entomology, University of Pretoria, South Africa RVF is a serious viral zoonotic disease causing wide-spread abortions, mortalities and illness in clinically susceptible species. The virus responsible for the disease is transmitted by mosquito vectors and epidemics coincide with periods of high rainfall when the vectors are abundant. However, low circulation of RVF virus (RVFV) and sporadic outbreaks of the disease often occur outside epidemic seasons, raising suspicion of existence of inter-epidemic maintenance hosts of RVFV, in the form of wildlife and other sub-clinically affected animals such as those in the Suidae Family. The current study was aimed at determining the sero-prevalence of RVF antibodies in suids from the 9 provinces of South Africa, to determine whether these animals had been exposed to RVFV infected mosquitos, have subsequently been infected and sero-converted. Approximately 4000 sera collected between 2007 and 2013 were screened with an indirect RVF IgG ELISA and 700 of these, were tested using serum neutralisation test (SNT). Overall ELISA sero-prevalence was 2.2 % and the rates per province ranged from 0.8 % to 6.3 %. Among the randomly selected sample subset tested, the SNT recovered a country-wide seroprevalence of 16.4 %, whereas ELISA prevalence was 0.1 %. The SNT results indicate that the serological prevalence of RVF in South African suids is higher than what is discernible by the indirect ELISA, a result that is likely due to lower binding capacity of the ELISA conjugate to suid IgG. The results indicate that suids exposed to RVFV seroconvert, corroborating earlier findings by investigators in Egypt. Further studies to investigate the role of these species in the epidemiology of RVF in enzootic areas are warranted. Agricultural Research Council Onderstepoort Veterinary Institute, No. 100 Old Soutpan Road, Private Bag X05, Onderstepoort 0110, Gauteng, South Africa [email protected]

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LINKAGES BETWEEN SOCIO-CULTURAL PRACTICES AND VULNERABILITY TO RIFT VALLEY FEVER (RVF) IN BARINGO COUNTY, KENYA

Edna Mutua

Graduate Fellow, International Livestock Research Institute, ILRI Nairobi, Kenya RVF is a zoonotic disease that affects domestic ruminants, particularly sheep, cattle and goats. In livestock and humans, RVF is spread through bites from infected aedes and culex mosquitoes. Additional avenues of human infections include contact with infected animal secretions, tissues and aerosols. In Kenya, RVF outbreaks have occurred ten times with the first recorded in 1931 and the last in 2006. During the 2006-2007 outbreak, RVF occurred in Baringo County for the first time. The outbreak was associated with ENSO related climatic anomalies. Through an on-going study on community adaptation to Malaria and RVF, which specifically focuses on how culture influences disease, data on socio-cultural practices in livestock production has been collected through focus group discussions and key informant interviews among the Tugen and Ilchamus communities of Baringo County. Preliminary findings show that both communities largely depend on livestock for their livelihoods. In terms of risk of exposure to RVF, both communities exhibit vulnerability based on their low level of awareness of the disease; consumption of meat from animals that die of diseases and unknown causes; disposal of dead animals; close contact with both healthy and sickly livestock; and management of human febrile illnesses. The study concludes that both communities are vulnerable to RVF and recommends that they should receive targeted awareness creation messages on the occurrence, transmission and prevention of RVF in order to decrease vulnerability to human and livestock infections. International Livestock Research Institute ILRI P. O. Box 30709-00100, Nairobi, Kenya [email protected]

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PERCEIVED RISK FACTORS AND RISK PATHWAYS OF RIFT VALLEY FEVER IN CATTLE IN IJARA DISTRICT, KENYA

Nelson O. Owange, William O. Ogara, Jacqueline Kasiiti a, P. B. Gathura, Sam Okuthe e,

Rosemary Sang c,d, Hippolyte Affognon c, Onyango Ouma b & Murithi Mbabu a University of Nairobi, Faculty of Veterinary Medicine, Department of Public Health Pharmacology and Toxicology, Nairobi, Kenya. a. Ministry of Agriculture, Livestock and Fisheries, State Department of Veterinary Services, Nairobi, Kenya. b. Institute of Anthropology, Gender & African Studies, University of Nairobi, Nairobi, Kenya, c. International Centre for Insect Physiology and Ecology (ICIPE), Nairobi, Kenya, d. The Center for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya. e. Emergency Centre for Transboundary Animal Diseases (ECTAD) Eastern Africa, FAO, UNoN, Gigiri, Kenya. Ijara district in Kenya was one of the hotspots of RVF during the 2006/2007 outbreak which led to human and animal deaths causing huge economic losses. The main constraint in the control and prevention of RVF is inadequate knowledge about the risks factors promoting its occurrence and maintenance. This study was aimed at understanding the perceived risk factors and risk pathways of RVF in cattle in Ijara to enable the development of improved community-based disease surveillance, prediction, control and prevention. A cross-sectional study was carried out from September 2012 to June 2013. Thirty-one key informant interviews were conducted with relevant stakeholders to determine the local pastoralists’ understanding of risk factors and risk pathways of RVF in cattle in Ijara district. The key informants rated the high presence of mosquitoes, availability of large herds of cattle and once in a while high rainfall leading to floods in the relatively flat land of the region to be the main risk factors. Close contact between wildlife and cattle was suggested to be another main risk factor for occurrence of RVF. The main risk pathways were infected mosquitoes that bite cattle while grazing and at watering points as well as the close contact between domestic animals and wildlife. The mobility of the cattle to markets and search of pasture suggested the likelihood of infection transfer over a wide area. The likelihood of contamination of the environment due to poor handling of carcasses and aborted foetuses during RVF outbreaks was considered an important pathway. The findings pointed that availability of mosquitoes, livestock and wildlife as well as rainfall leading to floods were the main risk factors towards occurrence and maintenance of RVF in cattle in Ijara. On the other hand, the contact between livestock and wildlife around watering points and grazing fields were perceived to be the main risk pathways for RVF in cattle in Ijara. The transmission through poor handling of carcasses was perceived to be negligible. As a result there is need to carry out regular participatory community awareness campaigns on handling of both domestic and wildlife carcasses for preparedness, prevention and control of any possible RVF epizootics. Additionally, monitoring of environmental conditions to detect enhanced rainfall and flooding should be prioritized for preparedness. Ministry of Agriculture, Livestock and Fisheries, State Department of Veterinary Services, Private Bag 00625, Nairobi, Kenya [email protected]

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Conclusions

- 78 -

- 79 -

CONCLUSIONS

INTER-REGIONAL CONFERENCE ON RVF NEW OPTIONS FOR TRADE, PREVENTION AND CONTROL

21 – 23 Avril 2015 Djibouti

Considering that

• Rift Valley Fever is recognised as a priority disease for the Greater Horn of Africa and Middle East regions and has been integrated into the regions’ 5-year action plan for GF-TADs

• RVF is a zoonosis and causes significant socio-economic impact during times of outbreak

• Livestock trade between the Horn of Africa and the Gulf countries is of significant importance to reduce poverty in the region especially in vulnerable populations such as pastoralist communities and women.

• The OIE has followed up on recommendations by previous meetings and has revised the Code Chapter on RVF including provisions for safe trade during inter-epizootic as well as during epizootic periods

• The tripartite (FAO, OIE, WHO) has developed One Health tools to facilitate reviews of competencies at the interface between Animal and Human Health Services

• The probability of new RVF outbreaks in the countries at risk such as Kenya, Somalia, Uganda, Tanzania, Sudan and South Sudan is high, given that this is year 8 after the last outbreaks and the high probability of a medium to strong El Nino event during the coming season, which may lead to above normal rains during the latter half of the year and that countries should therefore be considered as standing between the Early Warning Phase and the Alert Phase

• The Decision Support Framework developed by ILRI and partners has been updated and can assist the countries at risk to assess their level of preparedness

• The Clone 13 vaccine is still the only registered alternative to the Smithburn-based and inactivated vaccines, with registration only in South Africa and Namibia

• Despite the progress in research on promising new vaccines with potential DIVA capacity, durable immunity and improved safety, none of these candidate vaccines are on the market as yet.

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The Conference concludes:

That the countries in the regions should develop an attitude of preparedness rather than reactivity once a crisis is imminent.

On surveillance, outbreak prevention and early response

• Countries should recognise that RVF outbreaks might occur in the region within the next 18 months, given the extended time period of 8 years since the last outbreaks and the increased susceptibility of populations due to the turnover in livestock populations after the last severe draught (2010 – 2011) and the ENSO prediction indications, and are urged to make the following preparations:

o Urgently develop, evaluate and update, where appropriate, their national Contingency Plans using a One Health approach, e.g. by using the tools developed jointly by OIE/WHO/Worldbank with the support of FAO (Integrated IHR – PVS tool and Trans-sectorial Coordination Framework)

o Develop concrete national action plans for the Early Warning Period based on the updated Contingency Plans and the updated Decision Support Framework

o The national action plans should be prioritised and include updated risk maps and estimation of animal numbers in the risk areas

o Countries should heighten surveillance in high risk areas, e.g. increased monitoring of sentinel herds where available; and increased surveillance in markets or places where large numbers of animals are traded or congregate

• Countries previously affected by RVF should consider to start carrying out targeted vaccination campaigns in high risk areas

• Regional African and Middle East organisations including AU-IBAR, IGAD and AU-PANVAC should assist countries at risk to develop a detailed vaccination policy strategy based on the national risk maps

• International and regional organisations are encouraged to support this operational planning, preferably within the framework of already ongoing existing projects or within joint advocacy platforms for donor funding

On vaccine development

• Vaccine producing laboratories are encouraged to speed up the process to commercialise candidate vaccines in order to overcome the shortcomings of the currently existing vaccines such as availability, safety, efficacy and stability in line with OIE standards for vaccine quality

• In order to increase the uptake of preventive vaccination during the inter-epidemic period by farmers and the

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Veterinary Services, vaccine manufacturers are encouraged to develop live attenuated multivalent combination vaccines offering protection against multiple transboundary animal diseases and with an improved benefit/cost ratio as compared to monovalent RVF vaccines

• AU-PANVAC with the support of AU-IBAR is encouraged to carry out quality assessment of existing vaccines as well as an assessment of the production and delivery capacity of vaccine producers of registered vaccines (Smithburn, Inactivated, Clone 13) within a short time period

• OIE in collaboration with AU-PANVAC and IGAD should facilitate the establishment of RVF regional vaccine banks at regional level based on the results of the aforementioned assessment

On diagnosis of RVF

• Reference Laboratories and pharmaceutical companies are encouraged to increase the production of reagents necessary for serological detection of RVF IgM and IgG and to increase collaboration with AU-PANVAC for the evaluation, quality control, production and distribution of diagnostic assays/reagents to national laboratories

• Reference laboratories are encouraged to continue capacity building activities on RVF diagnosis and to consider twinning programmes within the framework of the OIE.

On trade

• Countries are encouraged to translate the revised OIE Code Chapter into their national legislation and regulations and reinforce its application; and to exchange information with trading partners on the disease situation in their countries

• Veterinary Services should regularly audit quarantine stations for compliance with national regulations and inter-governmental standards.

• IGAD and AU-IBAR are requested to support improvement of technical capacity of quarantine stations through the export quarantine network being formed

On communication

• International and regional organisations are urged to communicate these recommendations jointly via a Press Conference to attract sufficient attention

• National authorities should also disseminate these recommendations at the national level

• Countries should develop awareness campaigns among vulnerable populations such as farmers, abattoir workers, and other stakeholders

• National Authorities should establish regular communication channels between public health and veterinary authorities to ensure disease surveillance results are timely reported.

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- 83 -

Annexes

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- 85 -

CONFERENCE PROGRAMME

Tuesday, 21 April 2015 Time Topic Speaker

08.00 – 09.00 Registration Grace Omwega, Rita Rizk

09.00 – 10.30 Official Opening Statement by OIE RR / Middle-East Statement by OIE SRR / Eastern Africa Statement by WHO Statement by FAO Statement by AU-IBAR Statement by AU-PANVAC Statement by IGAD Secretariat Opening by the Guest of Honour

Ghazi YehiaPatrick Bastiaensen

Pierre FormentyEmmanuelle Guerne-Bleich

Ahmed El-SawalhyCharles Bodjo

Moh. Moussa MohamedMohamed Ahmed Awaleh

Objectives of the meeting Susanne Münstermann

Participants’ introductions and expectations Participants

Group photograph with Guest of Honour Photographer

10.30 – 11.00 Coffee break

SESSION 1 : SETTING THE SCENE

11.00 – 11.20 Recall of previous meetings, their outcomes and recommendations

S. Münstermann (OIE)

11.20 – 12.00 RVF in the Horn of Africa, East Africa, and the Middle East – a historical overview : • Animal health • Public health

Bouna Diop (FAO)Pierre Formenty (WHO)

12.00 – 12.40 Recent RVF outbreaks : • in north-western Africa • in southern Africa

Alessandro Ripani (OIE NA)Rachel Maluleke (ARC OVI)

12.40 – 13.00 Questions for clarification

13.00 – 14.00 Lunch

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SESSION 2 : CHALLENGES TO DISEASE CONTROL

14.00 – 14.20 Available control options Kariuki Njenga (KEMRI)

14.20 – 14.40 Vaccination strategies, vaccine availability and quality control

D. Goovaerts (GalvMED)

14.40 - 15.20 Vaccines • Vaccines currently used in the field and

their issues • Novel vaccines • Novel vaccines

Bethuel Nthangeni (OBP)

L. Maartens (Deltamune) Mehdi El Harrak (MCI)

15.20 – 15.40 Discussion

15.40 – 16.00 Coffee break

16.00 – 16.15 Diagnostic tests for RVF and role of Reference Laboratories: what is available?

Kariuki Njenga (KEMRI)Alison B. Lubisi (ARC – OVI)

16.00 – 16.15 Role of Reference Laboratories : twinning (South Africa – Yemen)

Alison B. Lubisi (ARC – OVI)Ghazi Yehia (OIE ME)

16.20 – 17.20 Research and development for RVF diagnostic tests: what is new? • Deltamune • PANVAC

L. Maartens (Deltamune)Charles Bodjo (PANVAC)

17.40 – 18.00 Discussion

20.00 Dinner Reception

Wednesday, 22 April 2015

Time Topic Speaker

SESSION 3 : TRADE ISSUES

09.00 – 09.20 OIE Code Chapters relevant to RVF and trade S. Münstermann (OIE)

09.20 – 09.40 Current livestock trade between the Horn of Africa and the Middle East. The new RVF OIE Code Chapter and what it means to inter-regional trade

Edgar ‘Chip’ Stem (OIE ad-hoc group RVF)

09.40 – 10.00 Perspective from the importing countries : KSA Abdelhamid El-Fadil

10.00 – 10.30 Discussion

10.30 – 11.00 Coffee break

11.00 – 13.00 Working session 1 : Case studies / Different scenarios

Gregorio Torres(facilitator)

13.00 – 14.00 LUNCH

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SESSION 4 : PREVENTION, BIOTHREAT AND EARLY WARNING

14.00 – 14.20 Surveillance systems in place Zelalem Tadesse (AU-IBAR)

14.20 – 14.50 Bridging WHO and OIE tools for the assessment of national capacities

S. de la Rocque (OIE/WHO)

14.50 – 15.10 Contingency planning for RVF : Kenya Austine Bitek (ZDU Kenya)

15.10 – 16.40 Working session 2 (including coffee break) Case studies / Contingency plans

Gregorio Torres(facilitator)

16.40 – 17.00 Decision – support framework for East Africa Bernard Bett (ILRI)

17.00 – 17.20 Early Warning Systems in place Assaf Anyamba (NASA)

17.20 – 17.40 The joint Early Warning release D. Beltrand-Acrudo (FAO)

Thursday, 23 April 2015

Time Topic Facilitators

07:00 – 12:00 Visit of the Djibouti Quarantine Facilities (Prima) Moussa Cheikh Ibrahim

12:00 – 13:00 Lunch at the Djibouti Quarantine Facilities (courtesy of PRIMA International C°)

13:00 – 14.00 Reports from the Working groups of Sessions 1 and 2 and resulting recommendations

Rapporteurs

SESSION 5 : REGIONAL COORDINATION

14.00 – 14.15 OIE Vaccine banks S. Münstermann (OIE)

14.15 – 14.45 • GF-TADs – Africa • GF-TADs – Middle East

Bouna Diop (FAO)Ghazi Yehia (OIE)

14.45 – 15.00 AU-IBAR James Wabacha (IBAR)

15.00 – 15.15 IGAD Ameha Sebsibe (IGAD)

15.15 – 15.30 Eastern African Epidemiology and Laboratory Networks (EAREN, EARLN)

Bouna Diop (FAO)

15.30 – 16.00 Discussion

16.00 – 16.30 Tea break

16.30 – 17.00 Conclusions

Closing remarks

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- 88 -

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- 89 -

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Case scenario 2 Consignment: 40,000 local breed sheep and goats with different origins and unknown history of previous vaccination. Rift Valley fever status of the country of origin: Last big outbreak of RVF occurred 4 years ago. The outbreak was controlled by a mass vaccination launched by the government. Since then, 2 human cases have been officially reported. The epidemiological studies carried out to investigate the human cases demonstrated a certain level of sporadic virus circulation in ruminants without causing significant losses. The latest public health data available indicate a human prevalence of 2%. Currently, the vaccination in ruminants is voluntary. There is only non-official data of vaccination coverage available and it is assumed to be low. Details of the movement: The movement is planned from an official coastal quarantine station which acts as hub before moving to the final importing country, probably within the Gulf Cooperation Council (GCC) region. There are no plans to vaccinate the sheep and goats with an approved RVF vaccine. The animals will be quarantined for 21 days in the approved coastal quarantine that is situated in an area with low vector activity and in which the quarantine operators routinely practice vector control through “fogging” with an approved and safe insecticide. Should any of the animals in the quarantine demonstrate a fever, they will be closely observed for signs of RFV disease. Questions: 1. What is the risk (very low, low, medium, high, very high) of introducing RVFV through this movement? 2. Which article of Chapter 8.13 of the Terrestrial Code applies? 3. What are the mitigation measures you will request to allow this movement? Please, provide the rationale if they differ from the Terrestrial Code provisions.

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Case scenario 3 Consignment: • 15,000 sheep and 1,000 camels. All camels are older than 1 year, all sheep and goats are older than 6 months. None of them have been vaccinated. • 200 kg of wool from different origins.

Rift Valley fever status of the country of origin: The country is experiencing a large number of outbreaks. There is social alarm and the farmers report important losses in the affected areas. All the human and animal cases are concentrated in the Southern part of the country. The Central and Northern provinces are not affected. The Northern provinces have never been affected by previous RVFV outbreaks. The country has an approved quarantine station along the coast which is unaffected by the outbreak with the nearest case 350 km away and most cases and outbreaks more than 500 km away. Strict movement controls in the affected areas of the country have been put in place by the Director of Veterinary Services and vaccination strategies including ring vaccination are being practiced. Details of the movement and proposed quarantine procedures: The sheep and camels come from farms located in a province in the North of the country bordering the country of destination. Before the shipment, all animals will be placed in an approved quarantine station following transport through areas of the country that remain clear and unaffected by the disease. The reception holding area is located 1 km from the quarantine. The quarantine is located in an area of low vector activity and mosquito fogging is practiced regularly in both the quarantine and the reception holding area. All animals will be vaccinated in the reception area with an appropriate vaccine and taken to the quarantine where they will be observed closely with temperatures monitored daily. All animals will be quarantined for 21 days following vaccination. Should any of the animals in the quarantine demonstrate a fever, they will be closely observed for signs of RFV disease. The wool has been collected by a local dealer presumably from several farms situated all around the country. Questions: 1. What is the risk (very low, low, medium, high, very high) of introducing RVFV through this movement? 2. Which article of Chapter 8.13 of the Terrestrial Code applies? 3. What are the mitigation measures you will request to allow this movement? Please, provide the rationale if they differ from the Terrestrial Code provisions.

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Case scenario 4 Consignment: 10 tons of sheep and goat and 1,000 kg of camel meat. Animals were slaughtered in a local slaughterhouse supervised by the veterinary authority. Rift Valley fever status of the country of origin: The country of origin reported some cases of RVF two years ago. There were no further reports since then. However the level of surveillance in the country is unknown Details of the movement: Before the shipment, the carcases were matured at more than 4°C in a controlled temperature room for at least 24 hours. Questions: 1. What is the risk (very low, low, medium, high, very high) of introducing RVFV through this movement? 2. Which article of Chapter 8.13 of the Terrestrial Code applies? 3. What are the mitigation measures you will request to allow this movement? Please, provide the rationale if they differ from the Terrestrial Code provisions.

Case scenario 5 Consignment: 100 semen straws from a 3 year old Boran bull registered in the Boran Society. The donor bull was kept in an insemination centre authorised by veterinary authorities. The owner claimed that the bull was vaccinated less than one year ago but no vaccination records are available. Rift Valley fever status of the country of origin: The country of origin reported some cases of RVF two years ago. There were no further reports since then. However the level of surveillance in the country is unknown Details of the movement: The semen straws will be transported in a nitrogen flask. Questions: 1. What is the risk (very low, low, medium, high, very high) of introducing RVFV through this movement? 2. Which article of Chapter 8.13 of the Terrestrial Code applies? 3. What are the mitigation measures you will request to allow this movement? Please, provide the rationale if they differ from the Terrestrial Code provisions.

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Case scenario 7 Consignment : An order of 5,000 cattle, 30,000 sheep, 20,000 goats and 1,500 camels purchased from markets all over the country. It will be the largest consignment in the year to respond to high livestock demand by importing country due to Ramadan. Rift Valley fever status of the country of origin: The country is currently considered to be in an inter-epizootic period, reporting epizootic events every 5-10 years. The last epizootic event was reported 8 years ago. This year, the country is experiencing abnormally high rainfall causing floods in areas of the country previously affected by RVF disease. There are already rumours and online press reports of people falling ill with an unknown disease and also increasing incidence of livestock abortions and mortality. In response to the environmental conditions and to the unofficial reports, the DVS has dispatched his rapid response team that investigates outbreaks in the affected areas, but at the moment, detailed field reports and lab results are not available. The last official vaccination campaign was carried out as response to the last large RVF outbreak 8 years ago. No official vaccination has been carried out since then. Providing healthy livestock is critical to maintain the trust between importing and exporting countries to ensure long-lasting trading relationship between both countries. Trading with RVFV infected countries could result in a trade ban with devastating consequences for the economy of the exporting country. Details of the movement: Cattle are generally sourced from areas of the country that have not been seriously affected by RVF in previous epizootics. Upon questioning by the DVS office, the manager of the quarantine station reports that as much as 20% of the camel and goats will come from areas that have historically experienced RVF epizootics and additionally, some of the sheep are also coming from these previously affected areas. The time schedule for the export is 28 days, covering : 17 days in the quarantine station, 1 day transit to and loading at the port in an area of the country that is not experiencing abnormally heavy rainfall, and 10 days on a clean and disinfected ship which is managed by the quarantine company. The quarantine station is located in a low vector activity area and the quarantine operators routinely practice vector control through “fogging” with an approved and safe insecticide. A decision needs to be made as to whether and under what conditions this shipment should be made. Questions: 1. What is the risk (very low, low, medium, high, very high) of introducing RVFV through this movement ? 2. Considering the socioeconomic consequences of the trade for the exporting country. Should this movement be allowed? If not, justify your answer. 3. If the movement is allowed. What measures described in the code (if any) or other additional measures would you use to mitigate the risk of introduction by this consignment and to build trust between both trade partners.

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REPORT OF THE WORKING GROUP SESSION 2

THE TASK OF THE WORKING GROUPS

Background Planning and preparedness is critical to effectively response to a RVF outbreak. It requires inter-sectoral collaboration involving veterinary, public health authorities and stakeholders at all levels. A contingency plan should be a well-articulated strategy document being both flexible and dynamic. It should define roles and responsibilities and it should provide details of the resources needed to effective contain and eliminate the disease as well as an action plan for efficiently mobilise both human and material resources. All described actions aiming to prevent or minimize the disease impact in human and animal population should meet the obligation of international Standards, namely the WHO International Health Regulations (IHR 2005) and the OIE International Standards (Terrestrial Animal Health Code and Manual of Diagnostic tests and vaccines for Terrestrial Animal). While it is not feasible to produce a model contingency plan that fits all situations and circumstances in the different countries, the main general principles should be taking in consideration when designing and evaluating national RVF contingency plans. The objectives of this exercise are: • Assess the state of play of the RVF contingency plans in the region • Facilitate participants with understanding of the roles and limitations in the

management of RVF outbreaks. • Promote the evaluation and the updating of existing contingency plans highlighting

the importance of establishing collaboration between Veterinary and Public Health Authorities in the preparedness and response to a RFV outbreak.

1. Surveillance for early detection The main objective of the surveillance section of a contingency plan is the early detection to RVF outbreak or the detections of the putative risk factors that can determinate the presence of the disease. The impact of a RVF outbreak usually corresponds to the number of epidemiological units or geographical distribution that have been affected at the moment the disease is first diagnosed. The suspicion or confirmation of a RVF case will trigger the actions described in the contingency plan. Based on your own experience, which components should be included in the surveillance section of a RVF contingency plan? Please, identify the strength and weakness of your contingency plan. Enumerate at least three strong and three weak components related to disease control and prevention.

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- 97 -

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THE REPORTS BY MODERATORS AFTER THE DISCUSSIONS WITH THE GROUPS

1. Surveillance for early detection (Moderator: Stephane de la Rocque) The Moderator reminded the audience on the classical drawing of the disease epidemiology with a very narrow time window for detection of disease in animals before the peak of disease spread. Against this background, he listed the strong points for facilitating surveillance for early detection of RVF as follows: • In most countries, based on history of the disease and retrospective data available, the

hotspots for outbreaks are known and can be targeted for surveillance activities • There is also sufficient knowledge of the ecology and epidemiology of the disease and

its vector available • However, the early warning surveillance should include meteorological monitoring as

well as vector activity monitoring • Surveillance protocols should be adjusted to this knowledge and should also include

monitoring of sentinel herds • Within geographical zones strategic points for surveillance need to be identified, for

example on an island surveillance is particularly important at the port and airport • It was noted that if the country is an exporting country there should be enough

incentive to carry out surveillance in order to maintain this status • Surveillance teams should be readily available, they should also make use of CAHW, if

available and training efforts of all staff involved in surveillance should be undertaken • The results of surveillance should be communicated in a clear and rapid manner • The negative points were summarised as follows: • Surveillance teams might face difficulties to access remote areas and suffer from lack

of infrastructure to carry out their work effectively • There is often a lack of human and financial resources to carry out surveillance • Teams might suffer from lack of training, particularly in sample taking and sample

shipment • Passive surveillance can play a major role but might be hampered if livestock owners,

particularly pastoralists do not have the culture of reporting • Livestock owners might not always interpret abortions as an early warning sign for

RVF, as it can be caused by so many other factors. • The results of laboratory tests on surveillance samples might be delayed as there are

no rapid tests available • Although many countries have Contingency Plans available, they are sector specific

and often lack inter-sectorial coordination • A lack of exchange of data and information is often observed • Government commitment to surveillance for a disease that occurs only sporadically

might be missing • In addition, willingness at local level to carry out such activities might also be missing • Surveillance activities are often project based and therefore lack sustainability over

longer time periods

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2. Disease control and prevention measures (Moderator: Austine Bitek) The moderator summarised the information he had received from the different groups into different categories. He first listed the components of disease control and prevention as understood by the groups: • Livestock vaccination • Surveillance – laboratory capacity • Vector control • Quarantine • Public education/communication On livestock vaccination, he listed the following points as important: • Although RVF vaccines are existing since a long time, they are often not readily

available to countries in the face of an outbreak since there is limited capacity to produce the vaccine in most of the infected countries

• The current vaccines have a short shelf life • Therefore there is a need for regional vaccine banks • Countries would like to receive guidelines on vaccination protocols during the different

periods of RVF (after an outbreak, during the inter-epizootic period etc.)

On laboratory capacity, he listed the following points: • Low diagnostic capacity in the affected countries • Test kits to be used in laboratories are not readily available and very costly • In general the capacity in laboratories to carry out PCR and virus isolation is limited

On quarantine, he noted the following observation: • Countries have a good legislative framework for quarantine stations, but in some cases

there is lack of reinforcement of this legislation

On vector control, he noted the following points: • Effective insecticides and larvicides are available but they are expensive, often with

residual effect on the environment • However, coverage when using them is usually very low • There is fear that repeated application might lead to resistance of the vectors to these

chemicals

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3. Communication and awareness (Moderator: James Wabacha) The moderator presented the contributions from the groups in the following categories:

(i) Information messages should include… (ii) Strength of communication and (iii) Weakness of communication.

On “information messages should include…”, he noted the following points: • Include some basic information about the diseases:

o Zoonotic and vector borne o Common signs in human and animal o Mainly animals affected o But animal products are safe

• Should be joint statements with Public Health to avoid conflicting messages • Clear chain of command to release messages • Only one authority and one focal person should be in charge of information

dissemination • An indication of the stakeholders to be targeted for the messages (vets, human

medics, livestock owners, abattoir personnel etc) • Include religious leaders in the awareness raising process • An indication on the need for coordination at all levels, local/regional/sectors • Massages should be tailored to periods before the outbreaks • Messages should provide regular updates on activities • Should clearly state that control efforts are under way • Should state how the diseases affects the stakeholders • Should emphasise transparency • How to detect and to identify that it is RVF? • Explain the mode of transmission • Messages should target the high risk areas and use local languages wherever possible • Include non-traditional modes of information dissemination like social media • Include messages during the recovery phase to inform on when to resume routine

practices • Modes of information dissemination could be:

o Radio, posters, TV, social media, official websites, print media, lectures/seminars

o The goal should be: be fast (not first), be honest, be right, be credible and consistent !

On the strength of communication, he noted: • It is an effective tool in reducing the impact of the disease, support provision of

accurate information and can avoid panic • In some countries the Communication Plan (CP) for RVF is not in place, but a multi-

sectorial technic working group is in place (e.g. Uganda) • Some countries have a communication strategy in place • Some countries have sufficient human capacity to undertake communication and

awareness activities • Some countries use their extension units, personal for this type of communication

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- 101 -

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- 102 -

4. Coordination and chain of command (Moderator: Susanne Münstermann) The moderator summarise the input she received from the groups as follows: • For most countries represented in the groups there exists a coordination unit or

mechanism between MoA/Livestock and the MoH; often this unit is based under the Prime Minister’s Office, which often has a special Officer for Public Health affaires whose responsibility it is to relay the messages to the next lower levels. Only few countries have also other sectors such as environment or security forces integrated into this coordination unit.

• However, quite a number of countries mentioned that there is no proper equilibrium between the two sectors (MoA and MoH) and that often MoA dominates this coordination unit and often also the distribution of funds

• Furthermore, this cooperation appears to be most active during crisis periods, rather than during “peace times” as visible for example in the number of meetings that take place

• The difficulty to maintain a rapid processing along the top-down steps of the chain of command in decentralised countries was mentioned, particularly in countries where animal health is integrated into Municipality Administrations, leading to a slowdown of processes up to the extent that they are no longer able to implement any urgent matters

• The speed of information such as on suspicious surveillance results from the bottom to the top for the top to make decisions, seems also to be slow in the majority of countries.

5. Legal framework (Moderator: Samuel Wakhusama) The moderator summarised the information received from the groups under different headings as shown below: On statutory provisions: • They can be found under the general Disease Control and Prevention Proclamations

Acts On notifications: • While notification of a disease outbreak is regulated under the Acts, notification of

outbreaks is in some cases seen as an indirect punishment to trade and therefore might be avoided. How can we improve on this situation and promote transparency in information sharing ? There is a clear need for awareness increase and communication

On compensation upon destruction: • Some countries have provisions for this in their CPs (Ethiopia, Tanzania), other don’t

(South Africa – but also no destruction) • Problems of funding and potentially open to abuse where identified

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On animal movement control and quarantine law: • There is a unified quarantine law in the GCC States • But there is no such harmonised regional approach in the Greater Horn of Africa

region • A need for harmonisation at national and regional level was identified • The autonomy of provinces or counties makes it often difficult to implement

movement control at country level in some countries – no legal support measures (e.g S. Africa)

On penalties: • They are currently vague and not specific to RVF – they are covered under the General

Animal Disease Control Act in form of Proclamations, tending to be less specific for RVF

On enforcement of compliance: • Inadequate capacity for policing (long borders) • Smuggling, rustling • In some cases no clear legal arrangement made to support enforcement The moderator also identified other issues related to the regulatory framework, which are summarised as shown below: On outdated legislation/inadequate legislation: • A structure is present for a legal framework but the CPs are outdated and seem not a

priority for some countries • In some cases draft CPs were developed but were not approved – they are shelved • In some cases, no Veterinary Statutory Body (Veterinary Board, etc) exists, e.g.

Somalia On vaccines: • GMO vaccines are being developed but no adequate legal frameworks for approval are

available in countries wishing to use them • Vaccination to be carried out based on risk assessment but not legal enforcement in

place in the event of an imminent outbreak • In some countries, no clarity on who bears the cost of vaccinations in an anticipated

outbreak situation, e.g. Kenya, Sudan the Governments pay, but the situation in other countries is less clear

On the “One Health” approach: • There is the need for legal text in CPs to link Animal and Human health aspects On coordination: • Police, Veterinary Services, Administration, Public Health need close coordination –

appears good in Kenya, poor in Tanzania (separate ministries do their own thing)

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LIST OF PARTICIPANTS

COUNTRY REPRESENTATIVES

BAHRAIN Dr Abbas Al Hayki Senior Veterinary Officer Control and Animal Health Directorate Ministry of Municipalities P.O.Box 251 Manama +973 17 79 74 26 +973 17 69 46 73 📱 +973 39 64 64 86 [email protected] [email protected] COMOROS Mr Miradji Soule Chef de service santé animale Direction nationale de l’élevage Ministère de la production BP 41 Moroni +269 775 60 26 +269 775 00 03 📱 +269 333 09 04 [email protected] [email protected] DJIBOUTI Dr Moussa Ibrahim Cheikh Directeur de l’élevage et des services vétérinaires Ministère de l’agriculture, de l’élevage et de la mer. BP 297 Djibouti +253 77 86 06 00 [email protected] Dr Ali Ibrahim Mohamed Chef de Service de contrôle alimentaire et vétérinaire Direction de l’élevage et des services vétérinaires Ministère de l’agriculture, de l’élevage et de la mer. BP 297 Djibouti +253 77 86 06 00 [email protected]

Dr Elmi Ali Ahmed Vétérinaire Direction de l’élevage et des services vétérinaires Ministère de l’agriculture, de l’élevage et de la mer. BP 297 Djibouti [email protected] Dr Abdi Mahamoud Elmi Vétérinaire Direction de l’élevage et des services vétérinaires Ministère de l’agriculture, de l’élevage et de la mer. BP 297 Djibouti +253 77 64 64 18 [email protected] EGYPT Dr Osama Mahmoud Ahmed Slim Chairman (CVO) General Organization for Veterinary Services First Nadi El Said Street Dokki - Giza 12618 Cairo +20 11 18 00 82 92 [email protected] [email protected] [email protected] ETHIOPIA Dr Hadgu Mendefro Senior Quarantine Expert Veterinary Services Directorate Ministry of Agriculture P.O.Box 62347 Addis Ababa +251 11 64 61 969 +251 11 64 62 095 📱 +251 913 26 221 [email protected] [email protected]

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Dr Gedion Yilma Defabachew Public Health Veterinarian Veterinary Services Directorate Ministry of Agriculture P.O.Box 62347 Addis Ababa +251 11 64 62 003 📱 +251 19 11 73 577 [email protected] [email protected] JORDAN Dr Majed Al Hawaosha Head of Animal Health Division Ministry of Agriculture P.O.Box 17110 Madaba +962 64 12 07 13 📱 +962 777 32 52 41 📱 +962 799 03 85 54 [email protected] KENYA Dr Kisa Juma Ngeiywa Director of Veterinary Services State Department of Livestock Ministry of Agriculture, Livestock and Fisheries Kabete P.O.Box 23355 00625 Nairobi 📱 +254 722 37 62 37 [email protected] Dr Kasiiti Lichoti Assistant Director of Veterinary Services State Department of Livestock Ministry of Agriculture, Livestock and Fisheries Central Veterinary Laboratories, Kabete, P.O.Box 23355 00625 Nairobi 📱 +254 733 70 76 85 [email protected]

KUWAIT Mr Khaled Almutawaa Head of Veterinary Laboratory Public Authority of Agriculture and Fisheries Kuwait City +965 55 03 32 22 [email protected] Dr Saad Jasim Al Anzi Head of Veterinary Quarantine Public Authority of Agriculture and Fisheries Kuwait City +965 66 700 918 [email protected] LEBANON Dr Mohamad Sokarie Veterinary Officer Animal Health Department Ministry of Agriculture Bir Hassan - Jnah Beirut 📱 +961 3 87 17 20 [email protected] OMAN Dr Sultan Al Ismaili Veterinary Epidemiologist Director General of Animal Wealth Ministry of Agriculture and Fisheries P.O.Box 2298 PC112 Muscat +968 99 38 03 16 [email protected] Dr Anwar Nasser Al Saadi Directorate of Animal Wealth Ministry of Agriculture and Fisheries 20413 Ibra +968 99 38 17 79 [email protected] QATAR Dr Farhoud Al-Hajri Head of Animal Resources Department Ministry of Environment P.O.Box 23211 Doha +974 44 56 04 00 +974 44 66 31 63 📱 +974 66 67 66 99 [email protected]

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Mr Saleh Al-Marri Head of Veterinary Services Section Animal Resources Department Ministry of Environment P.O.Box 23211 Doha +974 44 56 05 55 +974 44 65 43 90 📱 +974 55 85 95 80 [email protected] SAUDI ARABIA Dr Alarabi Mehidi Alomim Animal Health Department Ministry of Agriculture Riyadh +966 50 48 81 477 [email protected] Dr Abdelhamid El-Fadil KSA / Consultant Epidemiologist Sudan University of Science and Technology Khartoum +249 915 689 630 [email protected] SOMALIA Dr Habiba Hamud Ministry of Livestock, Forestry and Range Mogadishu +252 615 178 424 [email protected] Dr Ahmed Abdi GEDI Chief Veterinary Officer Ministry of Livestock, Forestry and Range Mogadishu +252 615 914 495 [email protected] [email protected] SOMALIA (SOMALILAND) Mr Warsame Haibeh Animal Health Director Ministry of Livestock Hargesia +252 63 44 46 174 [email protected] [email protected]

SOUTH SUDAN Dr Mabior Yuot Inspector of Veterinary Services Directorate of Veterinary Services Ministry of Livestock and Fisheries Industry P.O.Box 126 Juba +211 95 55 44 437 [email protected] [email protected] SUDAN Dr Kamal Tagelsir Elsheikh Elfaki Chief Veterinary Officer Undersecretary Ministry of Livestock P.O.Box 1111 Khartoum 📱 +249 91 23 38 522 [email protected] [email protected] SYRIA Dr Mohammed Riad Dayoub Head of Vaccine Production Vaccine Production Department Ministry of Agriculture and Agrarian Reform Bab Sharki – Airport Square, Al Hejaz Damascus +963 11 54 22 472 +963 11 54 24 761 📱 +963 93 37 46 913 [email protected] TANZANIA Dr Makungu Luka Selemani National Epidemiologist Directorate of Veterinary Services Ministry of Livestock and Fisheries Development 131, Nelson Mandela Road P.O.Box 9152 15487 Dar Es Salaam +255 75 44 32 113 📱 +255 68 55 12 765 [email protected] [email protected]

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Dr Mwananyanzala Dotto Maziku PVO Veterinary Public Health Directorate of Veterinary Services Ministry of Livestock and Fisheries Development 131, Nelson Mandela Road P.O.Box 9152 15487 Dar Es Salaam +255 22 28 62 592 📱 +255 76 44 95 881 [email protected] [email protected] UGANDA Dr Dan Tumusiime Senior Veterinary Officer Livestock Health Department Ministry of Agriculture, Animal Industry and Fisheries Lugard Avenue P.O.Box 513 Kampala 📱 +256 77 23 40 032 [email protected] Dr Noelina Nantima Principal Veterinary Officer Livestock Health Department Ministry of Agriculture, Animal Industry and Fisheries P.O.Box 513 Kampala +259 77 25 15 962 [email protected]

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SPEAKERS (except FAO and OIE)

Dr Assaf Anyamba Research Scientist GESTAR/USRA & Biospheric Sciences Laboratory NASA Goddard Space Flight Center Code 618 20771Greenbelt, MD UNITED STATES OF AMERICA +1 30 16 14 66 01 +1 30 16 14 66 95 [email protected] Dr Bernard Bett Scientist Food Safety and Zoonosis ILRI P.O.Box 30709 00100 Nairobi KENYA +254 20 422 34 53 +254 20 422 30 01 📱 +254 722 84 19 38 [email protected] Dr Austine Bitek Veterinary Epidemiologist Ministry of Agriculture, Livestock and Fisheries Zoonotic Disease Unit P.O.Box 20811 00202 Nairobi KENYA 📱 +254 721 606 743 [email protected] Dr Charles Bodjo Senior Diagnostics Officer Pan-African Veterinary Vaccines Centre AFRICAN UNION P.O.Box 1746 Debre – Zeit ETHIOPIA +251 913 48 90 79 [email protected]; [email protected]

Dr Mehdi El-Harrak Director R & D MCI Santé Animale Lot 157 ZI Sud Ouest, BP 278 28810 Mohammadia Rabat MOROCCO +212 52 33 03 132 +212 52 33 02 130 📱 +212 66 28 83 378 [email protected]; [email protected] Prof. Ahmed El-Sawalhy Director Inter-African Bureau for Animal Resources AU Kenindia Business Park Building Museum Hill, Westlands Road P.O.Box 30 786 00100 Nairobi KENYA +254 20 367 40 00 +254 20 367 43 41 📱 +254 710 888 810 [email protected] Dr Pierre Formenty Emerging and Dangerous Pathogens Team Alert and Response Operations Office Department of Communicable Diseases, Surveillance and Response (CDS/CSR) WHO 20 avenue Appia, 1211 Geneva (27) SWITZERLAND +41 22 79 12 550 +41 22 79 14 198 📱 +41 79 46 55 571 [email protected] Dr Danny Goovaerts Consultant Research Department GALVmed Langenberg 3, 2460 Lichtaart BELGIUM 📱 +32 4 87 65 79 86 [email protected]

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Dr Baratang Alison Lubisi Head of Virology Department ARC-OVI Onderstepoort Veterinary Intitute (ARC-OVI) Old Soutpan Road, Onderstepoort P/bag X05 Pretoria 0110 SOUTH AFRICA +27 12 529 92 33/ +27 12 529 9418 📱 +27 79 52 44 895 [email protected] [email protected] Dr Louis Maartens Research Veterinarian Research & Development Deltamune Jean Avenue 248, P.O.Box 14167 0140 Lyttelton SOUTH AFRICA +27 12 664 5730 +27 12 664 5149 📱 +27 82 899 8056 [email protected] [email protected] Mrs Moabi Rachel Maluleke Researcher Virology Department Agricultural Research Council Onderstepoort Veterinary Institute (ARC-OVI) Old Soutpan Road, Onderstepoort P/bag X05 0110 Pretoria SOUTH AFRICA +27 12 529 92 86 +27 12 52 99 249 📱 +27 82 400 4557 [email protected] [email protected] Mr. Mohamed Moussa Mohamed Director Agriculture and Environment Division IGAD Secretariat B.P. 2653 Djibouti DJIBOUTI +253 21 31 27 40 +253 21 35 69 94 📱 +253 77 81 45 27 [email protected]

Dr Kariuki Njenga Head of One Health Programme Kenya Medical Research Institute (KEMRI) P.O.Box 54840 00200 Nairobi KENYA 📱 +254 72 22 08 925 [email protected] Dr Mulalo Bethuel Nthangeni Chief Scientific Officer Research and Development Department Onderstepoort Biological Products (OBP) Old Soutpan Road, Onderstepoort P/Bag X07 0110 Pretoria SOUTH AFRICA +27 12 522 1549 +27 12 522 1591 📱 +27 82 885 7260 [email protected] Dr Chip Stem CEO Livestock Trade Services P.O.Box 2997 00100 Nairobi KENYA 📱 +254 72 22 05 703 [email protected]; [email protected] Dr Zelalem Tadesse Coordinator STSD Project Inter-African Bureau for Animal Resources AU Kenindia Business Park Building Museum Hill, Westlands Road P.O.Box 30 786 00100 Nairobi KENYA +254 20 367 43 52 📱 +254 71 88 65 692 [email protected] [email protected]

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Prof. James Wabacha Coordinator SMP-AH Project Inter-African Bureau for Animal Resources AU Kenindia Business Park Building Museum Hill, Westlands Road P.O.Box 30 786 00100 Nairobi KENYA +254 20 36 74 00 +254 20 36 74 341 📱 +254 72 28 74 870 [email protected] Dr Ameha Sebsibe Woldemariam Head, Livestock Programme ICPALD P.O.Box 47824 00100 Nairobi KENYA 📱 +254 721 23 30 45 [email protected]

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OBSERVERS

Dr Thomas Albrecht Veterinarian US Army Camp Lemonier BP 09363 DJIBOUTI +253 77 174 719 Dr Jodi Collins Veterinarian US Army Camp Lemonier BP 09363 DJIBOUTI +253 77 174 719 [email protected] Dr Ahmed Issa Dawud Laboratory Manager Technical Department PRIMA International Company DJIBOUTI +253 77 11 75 66 +251 91 14 08 989 [email protected] Dr Jeroen Kortekaas Virologist / Project Leader Central Veterinary Institute Wageningen University Edelhertweg 15, P.O.Box 65 8219 PH Lelystad THE NETHERLANDS +31 320 23 81 98 📱 +31 6 209 19 110 [email protected] Ms Boitumelo Moetlhoa Research Assistant Research and Development Department Onderstepoort Veterinary Institute (ARC-OVI) 10 Old Soutpan Road, Onderstepoort P/bag X05 0110 Pretoria SOUTH AFRICA +27 12 522 15 52 📱 +27 73 37 89 592 [email protected]; [email protected]

Dr Momtaz Shahein Deputy Director Animal Health Research Institute PRIMA International Company Nadi El Said St. Dokki – Giza EGYPT +20 10 07 321 765 [email protected] Dr Shebta Shebta Virology Department Animal Health Research Institute PRIMA International Company Mansoura EGYPT +20 10 919 79 167 +20 11 134 79 437 [email protected] Dr Khalid Omari Tadlaoui Director General MCI Santé Animale Lot 157 ZI Sud Ouest, BP 278 28810 Mohammadia Rabat MOROCCO +212 52 33 03 132 +212 52 33 02 130 📱 +212 66 11 41 860 [email protected] [email protected]

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(OTHER) REGIONAL AND INTERNATIONAL ORGANISATIONS

AU-IBAR / IGAD Dr Samuel Wakhusama VET-GOV Coordinator for the IGAD Region IGAD - ICPALD 1st floor, Jadala Place Ngong Lane, off Ngong Road P.O.Box 47824 00100 Nairobi KENYA 📱 +254 72 52 54 600 📱 +254 73 36 25 866 [email protected]; [email protected] ILRI Ms Edna Nduku Mutua Graduate Fellow Food Safety and Zoonoses Department ILRI ILRI Campus Kabete P.O.Box 30709 00100 Nairobi +254 20 422 3029 📱 +254 722 97 5578 [email protected] [email protected] CDC Dr Peninah Munyua Public Health Scientist Division of Global Health Protection CDC - Kenya Village Market P.O.Box 606 00621 Nairobi KENYA +254 202 713 008 📱 +254 710 602 787 [email protected] [email protected]

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FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS (FAO)

Dr Emmanuelle Guerne-Bleich Resident Representative FAO Lottissement du Héron Immeuble Moussa Bouraleh, Lot No. 16 BP 2588 DJIBOUTI [email protected] [email protected] Dr Markos Tibbo Regional Representative Regional Office for the Near East and North Africa FAO 11 Aleslah El Zerai St. P.O.Box 2223 Cairo EGYPT +20 23 33 16 143 / 6000 (ext. 2803) +20 23 74 95 981 [email protected] Dr Daniel Beltrán Alcrudo Animal Health Officer AGAH FAO Viale delle Terme di Caracalla 00153 Rome ITALY +39 (0) 6 570 53 823 📱 +39 (0) 6 570 53 057 [email protected] Dr Bouna Diop Regional Manager ECTAD Eastern Africa Food and Agriculture Organization of the United Nations Block P Level 3 United Nations Complex, UN Avenue, Gigiri P.O.Box 30470 00100 Nairobi KENYA +254 20 76 25 926 📱 +254 73 69 99 180 [email protected] [email protected]

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WORLD ORGANISATION FOR ANIMAL HEALTH (OIE)

HEADQUARTERS (PARIS) 12, rue de Prony 75017 Paris FRANCE +33 1 44 15 18 88 +33 1 42 67 09 87 Dr Susanne Munstermann Programme Officer Scientific and Technical Department [email protected] Dr Gregorio Torres Programme Officer Scientific and Technical Department [email protected] REGIONAL REPRESENTATION FOR THE MIDDLE EAST 1st Floor, Ministry of Agriculture bldg Furn El Chebak Beirut LEBANON Dr Ghazi Yehia Regional Representative for the Middle East [email protected] Dr Xavier Pacholek Programme Officer [email protected] Ms Rita Rizk Secretary [email protected]

SUB-REGIONAL REPRESENTATION FOR EASTERN AFRICA 4th Floor, Taj Towers, Upper Hill Road, Upper Hill P.O.Box 19687 00202 Nairobi KENYA +254 20 271 3461 Dr Patrick Bastiaensen Programme Officer [email protected] Ms Grace Omwega Administrative and Financial Assistant [email protected] Ms Loise Ndungu Secretary [email protected] SUB-REGIONAL REPRESENTATION FOR NORTH AFRICA Sub-Regional Representation for North Africa 17 Av d’afrique, El Menzah 5, BP 17 Tunis TUNISIA Dr Alessadro Ripani Programme Officer [email protected] SUB-REGIONAL REPRESENTATION IN BRUSSELS Bd du jardin Botanique, 55 1000 Brussels BELGIUM Dr Stéphane de La Rocque Programme Officer +41 14 41 15 19 73 📱 +41 6 76 57 90 99 [email protected]

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USEFUL WEBSITES

www.arc.agric.za/arc-ovi/Pages/ARC-OVI-Homepage.aspx

www.ars.usda.gov/Business/Docs.htm?docid=23464

www.au-ibar.org

www.cdc.gov/vhf/rvf/

www.cirad.fr/

www.cpc.ncep.noaa.gov/products/analysis_monitoring/enso_advisory/ensodisc.html

www.deltamune.co.za/

www.fao.org

www.fao-ectad-nairobi.org

www.galvmed.org

www.gcc-sg.org/eng/

www.icpald.org

www.igad.int

www.ilri.org

www.mci-santeanimale.com

www.nasa.gov

www.nasa.gov/topics/earth/features/riftvalley_fever.html

www.obpvaccines.co.za

www.oie.int

www.oie.int/en/animal-health-in-the-world/technical-disease-cards/

www.oie.int/en/international-standard-setting/terrestrial-code/access-online/

www.primaic.com

rea.au.int/en/RO/PANVAC

www.rr-africa.oie.int

www.rr-africa.oie.int/en/news/20121127.html

www.rr-middleeast.oie.int

visibleearth.nasa.gov/view.php?id=37025

www.wageningenur.nl/en/Expertise-Services/Research-Institutes/Central-Veterinary-Institute.htm

www.who.int

www.who.int/mediacentre/factsheets/fs207/en/

www.zdukenya.org

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R V F CHAPTER OF THE OIE TERRESTRIAL CODE (2014)

CHAPTER 8.13. INFECTION WITH RIFT VALLEY FEVER VIRUS

Article 8.13.1.

General provisions The aim of this chapter is to mitigate the animal and public health risks posed by Rift Valley fever (RVF) and to prevent its international spread. Humans and many animal species are susceptible to infection. For the purpose of the Terrestrial Code, RVF is defined as an infection of ruminants with Rift Valley fever virus (RVFV). The following defines the occurrence of RVFV infection:

• RVFV, excluding vaccine strains, has been isolated and identified as such from a sample from a ruminant; or

• antigen or ribonucleic acid specific to RVFV, excluding vaccine strains, has been identified in a sample from a ruminant epidemiologically linked to a confirmed or suspected case of RVF, or giving cause for suspicion of association or contact with RVFV; or

• antibodies to RVFV antigens which are not the consequence of vaccination, have been identified in a sample from a ruminant with either epidemiological links to a confirmed or suspected case of RVF, or giving cause for suspicion of association or contact with RVFV.

For the purposes of the Terrestrial Code, the infective period for RVF shall be 14 days. In areas where RVFV is present, epizootics of RVF may occur following favourable climatic, environmental conditions and availability of susceptible host and competent vector populations. Epizootics are separated by inter-epizootic periods. For the purposes of this chapter:

• 'area' means a part of a country that experiences epizootics and inter-epizootic periods, but which does not correspond to the definition of zone;

• 'epizootic of RVF' means the occurrence of outbreaks at an incidence substantially exceeding that during an inter-epizootic period;

• 'inter-epizootic period' means the period of variable, often long, duration, with intermittent low level virus activity, which is often not detected;

• ‘ruminants’ include dromedary camels. The historical distribution of RVF has been parts of the African continent, Madagascar, some other Indian Ocean Islands and the south western Arabian Peninsula. However, vectors, environmental and climatic factors, land-use dynamics, and animal movements may modify the temporal and spatial distribution of the infection. When authorising import or transit of the commodities covered in the chapter, with the exception of those listed in Article 8.13.2., Veterinary Authorities should require the conditions prescribed in this chapter relevant to the RVF status of the ruminant population of the exporting country. Standards for diagnostic tests and vaccines are described in the Terrestrial Manual.

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Article 8.13.2.

Safe commodities When authorising import or transit of the following commodities and any products made from them, Veterinary Authorities should not require any RVF related conditions, regardless of the RVF status of the ruminant population of the exporting country:

• hides and skins; • wool and fibre.

Article 8.13.3.

Country or zone free from RVFV infection A country or a zone may be considered free from RVFV infection when the disease is notifiable in the whole country and either:

• it meets the requirements for historical freedom in point 1 of Article 1.4.6.; or • met the following conditions:

o an on-going pathogen-specific surveillance programme in accordance with Chapter 1.4. has demonstrated no evidence of RVFV infection in ruminants in the country or zone for a minimum of ten years; and

o no indigenous human cases have occurred in the country or zone. A country or zone free from infection with RVFV will not lose its free status through the importation of ruminants that are seropositive, so long as they are either permanently identified as such or destined for immediate slaughter.

Article 8.13.4.

Country or zone infected with RVFV during the inter-epizootic period

A country or zone infected with RVFV, during the inter-epizootic period, is one in which virus activity is present at a low level but the factors predisposing to an epizootic are absent.

Article 8.13.5.

Country or zone infected with RVFV during an epizootic A country or zone infected with RVFV, during an epizootic, is one in which outbreaks of RVF are occurring at an incidence substantially exceeding that of the inter-epizootic period.

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Article 8.13.6.

Strategies to protect from vector attacks during transport Strategies to protect animals from vector attacks during transport should take into account the local ecology of the vectors and potential risk management measures include:

• treating animals with insect repellents prior to and during transportation; • loading, transporting and unloading animals at times of low vector activity; • ensuring vehicles do not stop en route during dawn or dusk, or overnight, unless the

animals are held behind insect-proof netting; • using historical and current information to identify low risk ports and transport routes.

Article 8.13.7.

Recommendations for importation from countries or zones free from RVFV infection For ruminants Veterinary Authorities should require the presentation of an international veterinary certificate attesting that the animals:

• were kept in a country or zone free from RVFV infection since birth or for at least 14 days prior to shipment;

AND • either:

o were vaccinated at least 14 days prior to leaving the free country or zone; or o did not transit through an area experiencing an epizootic during transportation to the place

of shipment; or o were protected from vector attacks when transiting through an area experiencing an

epizootic.

Article 8.13.8.

Recommendations for importation from countries or zones infected with RVFV during the inter-epizootic period

For ruminants Veterinary Authorities should require the presentation of an international veterinary certificate attesting that the animals:

• showed no sign of RVF on the day of shipment; • met one of the following conditions:

o were vaccinated against RVF at least 14 days prior to shipment with a modified live virus vaccine; or

o were held for at least 14 days prior to shipment in a mosquito-proof quarantine station which is located in an area of demonstrated low vector activity. During this period the animals showed no clinical sign of RVFV infection;

AND • either:

o did not transit through an area experiencing an epizootic during transportation to the place of shipment; or

o were protected from vector attacks when transiting through an area experiencing an epizootic.

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Article 8.13.9.

Recommendations for importation from countries or zones infected with RVFV during an epizootic

For ruminants Veterinary Authorities should require the presentation of an international veterinary certificate attesting that the animals:

• showed no sign of RVF on the day of shipment; • did not originate in the area of the epizootic; • were vaccinated against RVF at least 14 days prior to shipment; • were held for at least 14 days prior to shipment in a quarantine station,

which is located in an area of demonstrated low vector activity outside the area of the epizootic. During this period the animals showed no sign of RVF;

• either: o did not transit through an area experiencing an epizootic during transportation to the place

of shipment; or o were protected from vector attacks when transiting through an area experiencing an

epizootic.

Article 8.13.10.

Recommendations for importation from countries or zones not free from infection with RVFV For semen and in vivo derived embryos of ruminants Veterinary Authorities should require the presentation of an international veterinary certificate attesting that the donor animals:

• showed no sign of RVF within the period from 14 days prior to and 14 days following collection of the semen or embryos;

AND • either:

o were vaccinated against RVF at least 14 days prior to collection; or o were demonstrated to be seropositive on the day of collection; or o testing of paired samples has demonstrated that seroconversion did not occur between

semen or embryo collection and 14 days after.

Article 8.13.11.

Recommendations for importation of fresh meat and meat products from ruminants from countries or zones not free from infection with RVFV

Veterinary Authorities should require the presentation of an international veterinary certificate attesting that the entire consignment of meat comes from:

• ruminants which showed no clinical sign of RVF within 24 hours before slaughter; • ruminants which were slaughtered in an approved slaughterhouse/abattoir and were

subjected to ante- and post-mortem inspections with favourable results; • carcasses which were submitted to maturation at a temperature above 2°C for a

minimum period of 24 hours following slaughter.

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Article 8.13.12.

Recommendations for importation from countries or zones not free from infection with RVFV For milk and milk products Veterinary Authorities of importing countries should require the presentation of an international veterinary certificate attesting that the consignment:

• was subjected to pasteurisation; or • was subjected to a combination of control measures with equivalent performance as

described in the Codex Alimentarius Code of Hygienic Practice for Milk and Milk Products.

Article 8.13.13.

Surveillance

Surveillance should be carried out in accordance with Chapter 1.4.

• During an epizootic, surveillance should be conducted to define the extent of the affected area.

• During the inter-epizootic period, surveillance and monitoring of climatic factors predisposing an epizootic should be carried out in countries or zones infected with RVFV.

• Countries or zones adjacent to a country or zone in which epizootics have been reported should determine their RVFV status through an on-going surveillance programme.

To determine areas of low vector activity (see Articles 8.13.8. and 8.13.9.) surveillance for arthropod vectors should be carried out in accordance with Chapter 1.5. Examination of vectors for the presence of RVFV is an insensitive surveillance method and is therefore not recommended. 2014 © OIE - Terrestrial Animal Health Code.

21 - 23 April 2015Djibouti City, Djibouti

“RVF: NEW OPTIONS FOR TRADE, PREVENTION

AND CONTROL”

INTER-REGIONAL CONFERENCE MIDDLE EAST & HORN OF AFRICA

INT

ER-R

EGIO

NAL CO

NFER

ENCE M

IDD

LE EAST

& H

ORN

OF A

FRICA

“RVF : N

EW O

PTIO

NS FO

R T

RA

DE, PR

EVEN

TIO

N A

ND

CON

TRO

L”

OIE Sub-Regional Representation for Eastern AfricaFAO Emergency Centre for TADs (ECTAD) Eastern Africa

Nairobi, Kenya

Viale de terme di Caracalla, 00153 Rome, ITALYEmail: [email protected] | http://www.fao.org

12, rue de Prony, 75017 Paris, FRANCEEmail: [email protected] | http://www.oie.int


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