Scanning Near-field Optical Microscopy of Monocyte cells

SNOM Shear force Reflectance at 7.0 mReflectance at 8.05 m

Topographic resolution < 100 nm

Profile 1

l=7 m

l=7,3 m

l=8,05 m

SNOM Topography

Sample A

l=7,3 m

l=8,05 m

Sample B

SNOM Topography

l=7 m

• Good results, but…….the work starts now• Intensity normalization• Reduce the acoustic noise• Increase the signal: better focussing on the sample

and on the detector• Macroscopic characterization of the samples• A lot of experiments to be done, average on the

same sample and among different samples from the same patient and from different patients