SCHEDULE-AT-A-GLANCE2018 PNS ANNUAL MEETING

16.00-16.30 Coff ee Break The Atrium

16.30-18.00 Abstract Presentati ons

18.00-21.00 Welcome Reception Maryland Science Center Inner Harbor

SUNDAY, 22 JULY07.30-08.30 Poster viewing +breakfast/coff ee

Balti more Ballroom A&B

07.30-08.30 Clinical TrialsMaryland ABCD

08.30-09.00 Richard Bunge: Biology of NerveErika Holzbauer Maryland ABCD

09.00-10.30 6 Oral Abstracts (15 min each)Maryland ABCD

10.30-11.00 Coff ee BreakThe Atrium

11.00-11.30 Jack Griffin: Regeneration David Parkinson Maryland ABCD

11.30-12.30 10 Oral Posters (5 min each)Maryland ABCD

12.30-13.30 Lunch and Poster ViewingBalti more A&B

13.00-14.00 Poster Session – Stand-by TimesBalti more Ballroom A&B

14.00-18.00 INFLAMMATORY NEUROPATHY CONSORTIUM (INC) Maryland Ballroom ABCD

CHARCOT MARIE TOOTH & RELATED NEUROPATHIES (CMTR) Maryland Ballroom EF

DIABETES/ PAIN Watertable Ballroom

16.00-16.30 Coffee BreakThe Atrium

18.00-19.00 Ionis PharmaceuticalsMaryland EF

18.00- 19.00 Sponsor SymposiaMaryland ABCD

19.00-20.00 Junior recepti onThe Atrium

FRIDAY, 20 JULYTime TBA Registrati on

Main Lobby

SATURDAY, 21 JULYALL- DAY SATURDAY EDUCATION COURSE

Time TBA Registrati on Atrium

9.00-9.45 An Overview of Peripheral Nerve Anatomy and PathologySteve Scherer & PNS Educati on Committ eeMaryland Ballroom CDF

9.45-10.30 Disease mechanisms in the inherited neuropathies Vincent TimmermanMaryland Ballroom CDF

10.30-11.00 Coff ee Break The Atrium

11.00-12.00 New anti bodies and mechanisms in immune mediated neuropathy Claudia SommerMaryland Ballroom CDF

12.00-12.30 How I treat paraproteinaemic neuropathiesMichelle MauermannMaryland Ballroom CDF

12.30. 1400 Lunch The Atrium

14.00-14.45 Geneti c therapies in CMT and related disorders, how they work and clinical applicati ons John SvarenMaryland Ballroom CDF

14.45-15.15 The journey from preclinical to clinical trial -Lessons learnt Davide PareysonMaryland Ballroom CDF

15.15-16.00 What makes a good outcome measure and how to design one Josh Burns Maryland Ballroom CDF

MONDAY, 23 JULY07.00-08.30 Poster viewing +breakfast/coff ee

Balti more Ballroom A&B

07.30-08.30 CSL BehringMaryland Ballroom ABCD

07.30-08.30 Sponsor SymposiaMaryland Ballroom EF

08.30-09.00 Arthur K Asbury: GBS/CIDP/InflammatoryKevin O’Connor Maryland Ballroom ABCD

09.00-10.30 6 Oral Abstracts (15 min each)

10.30-11.00 Coffee Break The Atrium

11.00-11.30 PK Thomas: Inherited NeuropathiesAlessandra Bolino Maryland ABCD

11.30-12.30

10 Oral Posters (5 min each) Maryland Ballroom ABCD

12.30-13.30

PNS Annual General Meeting (all welcome)Maryland Ballroom ABCD

13.00- 14.00 Lunch/Poster Session Baltimore Ballroom A&B

14.00- 18.00 INFLAMMATORY NEUROPATHY CONSORTIUM (INC) Maryland Ballroom ABCD

CHARCOT MARIE TOOTH & RELATED NEUROPATHIES (CMTR) Maryland Ballroom EF

DIABETES/ PAIN Watertable Ballroom

16.00-16.30 Coff ee BreakThe Atrium

18.00- 19.00 Alnylam Maryland EF

18.00-19.00 GrifolsMaryland ABCD

19.00- 20.00 All member reception The Atrium

TUESDAY, 24 JULY07.30-08.30 Poster viewing +breakfast/ coffee

Balti more Ballroom A&B

07.30-08.30 Clinical TrialsMaryland Ballroom ABCD

08.30-09.00 Peter J Dyck LecturePeter McNaughtonMaryland ABCD

09.00-10.30 6 Oral Abstracts (15 min each)

10.30-11.00 Coffee BreakThe Atrium

11.00-11.30 Pembroke Lecture: Cell BiologyCraig BlackstoneMaryland ABCD

11.30-12.30 10 Oral Posters (5 min each)Maryland ABCD

12.30-13.30 Lunch and Poster ViewingBalti more Ballroom A&B

13.00-14.00 Poster Session – Stand-by Times

14.00-16.00 Late Breaking AbstractsMaryland ABCD

16.00-16.30 Coff ee BreakThe Atrium

16.30-17.30 Hot Topics/What’s NewMaryland ABCD

17.30- 18.30 Keynote Speaker + Prizes: Spinal muscular Atrophy from gene to treatment Arthur Burghes Maryland ABCD

19.00 PNS Closing Recepti on Camden Yards: Orioles vs. Red Sox Baseball Game

WEDNESDAY, 25 JULYIndividual Meetings

SUNDAY, 22 JULY INFLAMMATORY NEUROPATHY CONSORTIUM (INC)

1400-1430

1430-1500

1500-1600

1600-1630

1630-1700

1700-1730

1730-1800

INC Business Maryland ABCD

POEMS Satoshi Kuwabara Maryland ABCD

Oral Abstracts Maryland ABCD

Coffee Break Maryland Foyer

Debates: The next best clinical trial in CIDP: B-cell or T-cell immunomodulating therapy?Bernd Kieseier and Mazen Dimachkie Maryland ABCD

Mechanisms of Ig Mel Berger Maryland ABCD

Oral Abstracts Maryland ABCD

MONDAY, 23 JULY INFLAMMATORY NEUROPATHY CONSORTIUM (INC)

1400-1430

1430-1500

1500-1600

1600-1630

1630-1700

1700-1730

1730-1800

INC Business Maryland ABCD

Paraneoplastic or Sensory Neuropathies JC Antoine Maryland ABCD

Oral Abstracts Maryland ABCD

Coffee Break Maryland Foyer

Debates: Electrodiagnosis of Gullain-Barreˊ syndrome: new insights from analysis of re-vised diagnostic criteria and IGOS Nortina Shahrizalia and Yusuf Rajabally Maryland ABCD

MMN Leonard Van Den Berg Maryland ABCD

Oral Abstracts Maryland ABCD

SUNDAY, 22 JULY MONDAY, 23 JULY

CHARCOT MARIE TOOTH & RELATED NEUROPATHIES

CONSORTIUM (CMTR)

CHARCOT MARIE TOOTH & RELATED NEUROPATHIES

CONSORTIUM (CMTR)

1400-1430 Beyond Mendelian genomics: the expanding

concepts of heredity in CMT

Stephan Zuchner

Maryland EF

1430-1600 Oral Platform Presentations

Maryland EF

1600-1630 Coffee Break

Maryland Foyer

1630-1700 Structural variation causing inherited

neuropathies: a paradigm for genomic

organisation, chromatin interactions and

gene dysregulation

Marina Kennerson

Maryland EF

1700-1800 Platform Presentations

Maryland EF

1400-1430 PMP22 antisense oligonucleotides in rodent

models of the Charcot-Marie-Tooth disease

type 1A duplication.

John Svaren

Maryland EF

1430-1600 Oral Platform Presentations

Maryland EF

1600-1630 Coffee Break

Maryland Foyer

1630-1700 Overview on lesson learnt from novel

therapies for hereditary ATTR-neuropathy

Teresa Coelho

Maryland EF

1700-1800 Platform Presentations

Maryland EF

SUNDAY, 22 JULY Diabetes Consortium

MONDAY, 23 JULY

Diabetes Consortium

SUNDAY, 22 LY

1400-1415

1415-1435

1435-1455

1455-1515

1515-1535

Introduction to the Diabetic Neuropathy

Consortium

Christopher Gibbons

Watertable Ballroom

Keystone Target Talks

Obesity Mechanisms as a Targetable

Endpoint in Diabetic Neuropathy

Doug Wright

Watertable Ballroom

Keystone target talk- (Lipids and

Neuropathy)

Mark Yorek

Watertable Ballroom

Nox5 as a therapeutic Target

Stephanie Eid

Watertable Ballroom

Stem Cells as a Potential Treatment in

Dia-betic Neuropathy

Nakamura

Watertable Ballroom

1535-1600 Muscarinic Receptors as a Targetable End-

point in Diabetic Neuropathy

Paul Fernyough

Watertable Ballroom

1600-1630 Coffee Break

Maryland Foyer

1630-1700 Insulin Signaling Pathways as a Potential

Therapeutic Target in DPN

Doug Zochodne

Watertable Ballroom

1700-1730 Oral Platform Presentations

Watertable Ballroom

1730-1800 Oral Poster Presentations

Watertable Ballroom

1400-1430 Moderated Panel Debate Neurophysiology

endpoint talks (EMG, QST, Autonomic )

Vera Bril, James Russell, Amanda Peltier

Moderating: Rob Singleton

Watertable Ballroom

1430-1500 Moderated Panel Debate: Structural

endpoint talks (CCM, skin biopsy, sural

nerve biopsy)

Rayaz Malik, Michael Polydefkis and Gordon

Smith

Watertable Ballroom

1500-1520 Perspective on endpoints

Eva Feldman and Roy Freeman

Watertable Ballroom

1520-1540 What’s new in DLRPN

Jim Dyck

Watertable Ballroom

1540-1600 What’s new in TIND

Christopher Gibbons

Watertable Ballroom

1600-1630 Coffee Break

Maryland Foyer

1630-1700 Diabetic Peripheral Neuropathy and the

Opioid Crisis

Brian Callaghan

Watertable Ballroom

1700-1730 Oral Platform Presentations

Watertable Ballroom

1730-1800 Oral Poster Presentations

Watertable Ballroom