SCHOOL REPORT 2014 - University of Otago · 4 PHCY343 Drug Disposition and Pharmacokinetics 12 Dr...

School of Pharmacy Te Kura Matauraka Wai-whakaora

SCHOOL REPORT 2014

Contents

Staff as at December 2014 ............................................................................................... 1

Teaching Programme ......................................................................................................... 3

Enrolments in 2014 ............................................................................................................ 8

Prizes and Awards for 2014 ............................................................................................ 9

Graduates in 2014 ............................................................................................................ 10

Research Statistics ............................................................................................................ 12

Grants ................................................................................................................................. 13

Current PhD Students .................................................................................................... 14

BPharm Honours Programme ....................................................................................... 17

Publications – Journal ...................................................................................................... 19

Conference Presentations .............................................................................................. 24

Conference Attendance ................................................................................................. 31

Seminars ............................................................................................................................. 35

1

Staff as at December 2014

Professor and Dean

Stephen Duffull, DipPharm (CIT) MPharm PhD (Otago) RegPharmNZ FNZCP RegPharmNZ

MPS

Professors

Sarah Hook, BSc(Hons) PhD (Otago) ASI NZFSS

Pauline Norris, BA MA (Cant) PhD (Well)

Ian Tucker, BPharm(Hons) PhD (Qld) FNZCP FCRS RegPharmNZ MPS

Associate Professors

Rhiannon Braund, BSc BPharm PhD (Otago) FNZCP RegPharmNZ MPS

Natalie Medlicott, BPharm PhD (Otago) RegPharmNZ MPS

Joel Tyndall, BSc(Hons) (Monash) PhD (Qld)

Senior Lecturers

Shyamal Das, MPharm (B’lore) PhD (Monash)

James Green, BA(Hons) PhD (Otago)

Susan Heydon, BA(Hons) DHMSA (London) MA PhD (Otago) DHMSA Arlene McDowell, BSc(Hons) MSc (Melb) PhD (Otago)

Dorothy Saville, BPharm(Hons) MSc PhD (Syd)

Alesha Smith, BSc MSc (Otago) PhD (UQ)

June Tordoff, BPharm(Hons) MPharm (Brad) PhD (Otago) MRPharmS RegPharmNZ MPS

Lecturers

Hesham Al-Sallami, BPharm PGDipClinPharm MClinPharm (Otago) ANZCP RegPharmNZ

MPS

Vishal Diwan, MPharm (Punjab) PhD (Qld)

Allan Gamble, BMedChemAdv PhD GCertBus (W’gong)

Prasad Nistala, MPharm PhD GradDipClinPharm (Sydney) AACPA

Shakila Rizwan, BPharm, PhD (Otago) Andrea Vernall, BSc (Hons) PhD (Cant)

Greg Walker, MSc PhD (Otago)

Daniel Wright, BScPharm (Dal) MA (Brist) MSc PhD (Otago) RegPharmNZ

Senior Teaching Fellow

David Schmierer, BAppSci (Swinburne) MAACB CChem MRACI MRSC

Professional Practice Fellows

Kate Chesney, BPharm GDipBHL (Otago) RegPharmNZ MPS

John Fraser, BSc (Otago) RegPharmNZ MPS

Nicola Hewson, BPharm (Otago) RegPharmNZ MPS

Anita Olivier, DipPharm (Natal) PGCertTertT (Otago) RegPharmNZ MPS

Aynsley Peterson, BPharm PGCertPharm (Otago) RegPharmNZ MPS

James Windle, DipPharm (CIT) DipBusAdmin MBS (Massey) BPharm MClinPharm

PGCertTertT (Otago) AFAIPM MNZCP RegPharmNZ MPS

2

Research Staff

Biju Balakrishnan, BVSc AH (Kerala Ag) MVSc (IVRI) PhD (Auck)

Olaf Bork, DipIIng DrIng (Bremen)

Thomas Harper, MSc Computer Science (Otago)

Rohit Jain, MSc (Greenwich), PhD (Otago)

Chanaka Kaluarachchi

Christopher Wicky, BSc MSc (Otago)

Hu Zhang, MB (Bengbu) MD (Anhui) PhD (Otago)

Administrative Staff

Denise Botting

Kathy Ferguson, DipPol

Jane McAuslan, BCom (MANT) NZCE (Civil)

Vicky McLeod, Nat Cert Pharm Tech

Laura McNeil, Cert BASC

Dorothy Scott - fixed term position

Gwen Slote, BA (Washington)

Sarah Wilson - on parental leave

Technical Staff

Michael Broughton, MSc (Otago)

Glenys Donaldson

Julie Harwood, NDS

Tim Campbell, BSc (Information Science) (Otago)

Kevin Crump, BSc (Otago)

Pummy Krittaphol, BSc(Hons) RPharm (Rangsit) MSc (Mahidol) PGDip MSc PhD (Otago)

Joanne Preston, NZCS BSc (Massey)

Lisa Reid, Cert Disp Tech

Len Stevenson, NZCS PGCertHSci (Otago)

Brian Young, NZCE

Contracted Teaching Staff

Linda Bryant, BPharm MClinPharm (Otago) PhD (Auck) MPS

Bevan Clayton-Smith, BPharm MClinPharm (Otago) RegPharmNZ MPS

Keith Crump, DipPharm (CIT) RegPharmNZ

Alison Davies, DipPharm (CIT) DipHospPharm (Syd) MMedSci (Newcastle)

John Dunlop, PGDipPharm MPharm (Otago) FACPP MCPP FNZCP MRPharm DPharm

(Auck) MPS

Sunita Goyal, BSc DipPharm MClinPharm (Otago) MPS

Adele Print, BPharm MClinPharm (Otago)

David Woods, BSc(Hons) (Manch) MPharm (Otago) MPS

Honorary Professors

David Jones, BSc (Hons Pharmacy)(Queens Belfast) PhD (Pharmaceutics)(Queens Belfast)

DSc (Queens Belfast)

John Murphy, PharmD (Florida) FCCP FCP

Thomas Rades, BSc(Pharm) (Hamburg) PhD (Braunschweig)

Clare Strachan, BPharm PhD (Otago)

3

Teaching Programme

Bachelor of Pharmacy Degree (BPharm) 2014

Associate Dean, Admissions: Professor Ian Tucker

Associate Dean, Academic: Associate Professor Natalie Medlicott

Director, Undergraduate Programmes: Associate Professor Rhiannon Braund (until

April), Mr David Schmierer (from June to November)

Student Support Coordinator: Dr Shakila Rizwan

Student Support Coordinator: Mr David Schmierer/Dr Allan Gamble

First Year (Common Health Sciences First Year) Credit Points

BIOC 192 Foundations of Biochemistry 18

CELS191 Cell and Molecular Biology 18

CHEM191 The Chemical Basis of Biology and Human Health 18

HEAL192 Foundations of Epidemiology 18

HUBS191 Human Body Systems 1 18

HUBS192 Human Body Systems 2 18

PHSI191 Biological Physics 18

Second Year Credit Points PHCY219 Microbiology and Immunology (for BPharm) 12

Dr Judith Bateup (Microbiology)

PHCY231 Biochemistry (for BPharm) 7

Dr Alan Carne (Biochemistry)

PHCY251 Physiology (for BPharm) 17

Dr Phil Sheard (Physiology)

PHCY254 Physical Pharmacy A 12

Dr Shakila Rizwan

PHCY255 Physical Pharmacy B 12

Dr Greg Walker

PHCY256 Biopharmaceutical Chemistry 12

Mr David Schmierer

PHCY258 Introduction to Drug Action 12

Associate Professor Joel Tyndall

PHCY259 Quality of Medicines 12

Dr Allan Gamble

PHCY263 Principles of Pharmacy Practice 24

Dr Susan Heydon

Third Year Credit Points

PHCY315 Human Disease 12

Ms Catherine Ronayne (Pathology)

PHCY340 Essentials of Drug Action 12

Dr Gregory Giles (Pharmacology & Toxicology)

PHCY342 Drug Delivery Systems 12

Dr Arlene McDowell

4

PHCY343 Drug Disposition and Pharmacokinetics 12

Dr Dorothy Saville

PHCY344 Professional Pharmacy Practice A 12

Dr James Green

PHCY345 Quality Use of Medicines A (modules), Mr David Schmierer 50

Gastrointestinal Disorders, Dr June Tordoff

Infectious Diseases, Professor Sarah Hook

Respiratory Disorders, Professor Stephen Duffull

Endocrine Disorders, Dr Vishal Diwan

Cardiovascular, Dr Andrea Vernall

PHCY346 Professional Pharmacy Practice B 10

Mr James Windle

Fourth Year Credit Points PHCY470 Elective Study 12

Professor Pauline Norris

PHCY471 Quality Use of Medicines B (modules), Dr Prasad Nishtala 46

Oncology & the Immunocompromised patient, Professor Sarah Hook

Reproduction, Associate Professor Rhiannon Braund

Musculoskeletal, Mr Hesham Al-Sallami

PHCY472 Professional Pharmacy Practice C 16

Dr Susan Heydon

PHCY473 Quality Use of Medicines C (modules), Dr June Tordoff 46

Central Nervous System Disorders, Dr Prasad Nishtala

Dermatology, Mrs Nicky Hewson

Haematology, Mr Hesham Al-Sallami

Special Populations, Associate Professor Natalie Medlicott

Medicines Management, Ms Aynsley Peterson

Bachelor of Pharmacy Honours Degree (BPharm Hons) 2014

Programme Co-ordinator: Dr Shyamal Das

Fourth Year Credit Points PHCY480 Honours Research Project 36

Dr Shyamal Das

PHCY481 Quality Use of Medicines B (modules), Dr Prasad Nishtala 46

Oncology & the Immunocompromised patient, Professor Sarah Hook

Reproduction, Associate Professor Rhiannon Braund

Musculoskeletal, Mr Hesham Al-Sallami

PHCY482 Professional Pharmacy Practice C 16

Dr Susan Heydon

PHCY483 Quality Use of Medicines C (modules), Dr June Tordoff 46

Central Nervous System Disorders, Dr Prasad Nishtala

Dermatology, Mrs Nicky Hewson

Haematology, Mr Hesham Al-Sallami

Special Populations, Associate Professor Natalie Medlicott

Medicines Management, Ms Aynsley Peterson

5

Postgraduate Professional Programmes

Associate Dean, Postgraduate Professional Programmes: Professor Pauline Norris

Master of Clinical Pharmacy (MClinPharm)

The degree may be achieved either:

by passing PHCX506 and PHCX512, and submitting a research dissertation (PHCX590) OR

by passing PHCX506 and submitting a thesis (PHCY5A) having previously passed PHCX512.

Credit Points

PHCX506 Research Methods 30

Dr James Green

PHCX512 Advanced Clinical Pharmacy 30

Professor Stephen Duffull

PHCX590 Dissertation 30


PHCY5A Thesis 90


Postgraduate Diploma in Clinical Pharmacy (PGDipClinPharm) The diploma may be achieved by passing any four of PHCX522, PHCX523, PHCX524, PHCX541,

PHCX542; or by passing PHCX512, PHCX525, PHCX541, PHCX542.

Credit Points

PHCX522 Applied Clinical Pharmacy 1 30

Dr Linda Bryant

PHCX523 Applied Clinical Pharmacy 2 30

Professor John Murphy

PHCX524 Pharmacoeconomics and Drug Evaluation 30

Ms Alison Davies

PHCX525 Core Clinical Pharmacy 30

Dr Linda Bryant/ Professor John Murphy

PHCX541 Medicines Information 30

Dr Dan Wright

PHCX542 Medicines Management 30

Dr Dan Wright

PHCX547 Medicines and Culture

Dr Susan Heydon 30

PHCX548 Pharmaceutical Policy

Professor Pauline Norris 30

Postgraduate Certificate in Pharmacy (PGCertPharm) The programme shall consist of an approved paper or papers to the value of 60 points,

which must be as specified in the schedule of endorsed options if the certificate is to be

endorsed in an area of specialisation.

Credit Points

Endorsed Option Medicines Management (PGCertPharm MEMA)


Dr Dan Wright

6

PHCX542 Medicines Management 30

Dr Dan Wright

Endorsed Option Social Pharmacy (PGCertPharm SOPH)


Dr Dan Wright

PHCX547 Medicines and Culture 30

Dr Susan Heydon

PHCX548 Pharmaceutical Policy 30


Any one of the above two papers or one other paper to the value of 30 points

Postgraduate Certificate in Pharmacist Prescribing

(PGCertPharmPresc) This programme shall consist of papers PHCX601 Principles of Prescribing and PHCX602

Prescribing Practicum, both papers have a value of 30 points each, a total of 60 points for

the programme. This programme may be completed after a student gains the

PGDipClinPharm.

Credit Points

PHCX601 Principles of Prescribing 30

Ms Adele Print

PHCX602 Prescribing Practicum 30

Ms Adele Print

7

Research-Based Degree Programmes Associate Dean, Research | Professor Sarah Hook

Doctor of Philosophy (PhD)

The degree of Doctor of Philosophy is awarded on the basis of the submission of a thesis.

The thesis should give evidence of the candidate's ability to carry out research, that the

candidate has shown originality and independence, and that the candidate has made a

significant contribution to knowledge in the particular field. It is expected that some of the

work in the thesis would be worthy of publication. The research should be of a kind which a

diligent and competent student might reasonably be expected to complete within three

years of full-time study.

Master of Pharmacy (MPharm) The degree may be awarded in any area of Pharmacy.

The degree may be achieved by passing PHCY501-504, and submitting a thesis (PHCY5). In

place of one of the papers PHCY501-504, candidates may take either PHCX506 or any two

of HASX411, HASX412 and HASC413.

Postgraduate Diploma in Pharmacy (PGDipPharm) The degree may be awarded in any area of Pharmacy.

Credit Points

The degree may be achieved by passing PHCY501-504.

PHCY501 Elective Studies 30




Postgraduate Certificate in Pharmacy (PGCertPharm)

A non-endorsed option has been undertaken by graduate students who complete a 60-point

research dissertation for the award of PGCertPharm.

Credit Points

PHCY590 Dissertation 60

8

Enrolments in 2014

Undergraduate 2014

Year 1 not applicable*

Year 2 144

Year 3 157

Year 4 144

*selection into the BPharm programme occurs at the end of the first year

Postgraduate Programmes Student Numbers

Postgraduate Certificate in Pharmacy

Medicines Management 38

Research 0

Social Pharmacy 0

Pharmacist Prescribing 0

Postgraduate Diploma in Clinical Pharmacy 16

Postgraduate Diploma in Pharmacy 1

Master of Clinical Pharmacy 2

Master of Pharmacy* 0

PhD 39

*currently not enrolling students into these programmes

9

Prizes and Awards for 2014

Undergraduate

FOURTH YEAR

Leanne Soo - Christina White prize (Student with best overall achievement in the BPharm

degree overall)

Holly Hayne - Pharmaceutical Society of New Zealand prize

Holly Hayne - NZHPA Clinical pharmacy prize

Vibhuti Patel - Pharmacy Defence Association prize

Vibhuti Patel - Douglas Pharmaceuticals Pharmacy Practice Fourth Year prize

Kirsten Allen - Thomson Reuters Pharmacy prize

THIRD YEAR

Kit Yue Chan - Pharmaceutical Society of New Zealand prize

Nevin Zhong – Ken Campbell Memorial prize in pharmacy practice

Brittney Young – Douglas Pharmaceuticals Pharmacy Practice Third Year prize

Kit Yue Chan – NZ Hospital Pharmacists’ Association – Syd Little Memorial prize

Kit Yue Chan – Otago Pharmacological Association prize

SECOND YEAR

Natalie Fleming – Toniq prize

Helen Lee – NZ Controlled Release Society Pharmaceutics prize

Madoka Murayasu – Pharmacy Guild of NZ Inc. Pharmacy Practice prize

Natalie Fleming – UBS Pharmaceutical Chemistry prize

Postgraduate PGCertPharm (MEMA)

Michaela Smith – Best overall grade

PGDipClinPharm

Kiri Aikman – Best overall grade

PHCX512 Advanced Clinical Pharmacy

Catherine Street – Best overall grade

10

Graduates in 2014

Doctor of Philosophy Mudassir Anwar

Title: A prospective exploration of people's experiences of and responses to

symptoms in NZ and Pakistan

Supervisor: Dr James Green, Prof. Pauline Norris, Prof. Nadeem Irfan Bukhari

Franziska Huschmann

Title: Investigating resistance in infectious diseases

Supervisor: Assoc. Prof. Joel Tyndall, Prof. Richard Cannon, Prof. Kurt Krause

Chakradhar Lagishetty

Title: Covariates in pharmacometrics

Supervisor: Prof. Stephen Duffull, Assoc. Prof. Parry Guilford

Zongquan (Ellen) Ou

Title: Pre-formulation of antioxidant phytochemicals from Sonchus oleraceus L. (puha)

Supervisor: Dr Arlene McDowell, Prof Thomas Rades, Mr David Schmierer

Katie Owens

Title: Clinical pharmacology and toxicology of paracetamol in patient populations

Supervisor: Assoc. Prof. Natalie Medlicott, Dr David Reith

Madhu Shankar

Title: Validating essential enzymes as targets for new broad spectrum antifungal

compounds

Supervisor: Assoc. Prof. Joel Tyndall, Dr Brian Monk

Sachin Surwase

Title: Characterisation and optimisation of amorphous suspensions

Supervisor: Dr Dorothy Saville, Dr Clare Strachan

Postgraduate Certificate in Pharmacy (no endorsement) (PGCertPharm)

Hanisah Ahzari

Keeho (Arnold) Lee

Master of Clinical Pharmacy (MClinPharm)

Joanne Chong

Postgraduate Diploma in Pharmacy (PGDipPharm)

Santoria Utufua

Postgraduate Diploma in Clinical Pharmacy (PGDipClinPharm)

Kiri Aikman with Distinction

Leonard Bagley with Distinction

Nadine Bailey with Distinction

11

Helen Cant with Credit

Grace Chan with Credit

Jessica Dodd with Distinction

Michelle Fang with Distinction

Catherine Herd with Distinction

Lisa Jackson with Distinction

Hsiang-Yu (Johnny) Lai with Credit

Louise Lord with Distinction

Brijul Morar with Distinction

Stephanie Noble with Distinction

Sally Overton with Credit

Disha Patel with Credit

Rakhee Raghunandan with Distinction

Cathy Street with Distinction

Postgraduate Certificate in Pharmacy (endorsed in Medicines Management)

(PGCertPharm MEMA)

Katherine Boulton

Abby Calder

Gail Cowles

Katie Davis

Claire Fraser

Kate Griffin

Tess James

Tsz Yu (Wendy) Lee

Samuel Loevendie

David Lu

Patricia Marimuthu

Mohammed Mohammed

Dhairesh Patel

Dain (Diana) Phone

Jessica Rickard

Tamsin Roper

May-Wei (Violet) Shan

Michelle Singh

Michaela Smith

Brendon Stewart

Priyanka Thakor

Joyce Tiong

Timothy Walker

Rebecca Wright

Lily Young

Postgraduate Certificate in Pharmacy (endorsed in Social Pharmacy)

(PGCertPharm SOPH)

Nil

Postgraduate Certificate in Pharmacist Prescribing (PGCertPharm Presc)

Nil

12

Research Statistics Publications 2014

Authored Book – Research 0

Chapter in Book 0

Edited Book – Textbook & Other 1

Journal – Research Articles 56

Journal – Research Other 11

Journal – Professional & Non-Research 2

Conference Contributions

- Published Proceedings and Poster Presentations 31

- Verbal Presentation & Other Outputs 36

Grant Funding (approximately) 2014

Research GST exclusive $393,166

13

Grants Principal

Investigators Title of Project Funder Value

Alesha Smith Integrating patient data to

optimise medicines and reduce

polypharmacy

Health Research

Council

$158,933

Prof. Sarah Hook Use of the dual COX/LOZ

inhibitor licofelone for treatment

of cancer

Laurenson Award $11,484

Dr Andrea Vernall Integrated preparative high

pressure liquid shromatography

(prep-HPLC) system consisting of

a binary pump, autosampler,

column oven, variable wavelength

UV-Vis detector and associated

software

Lottery Health

Research (Research

Equipment Costs)

$19,275

Assoc. Prof.

Rhiannon Braund

Medicines information provision

by pharmacists in New Zealand

secondary care

NZPERF $5,792

Prof. Sarah Hook Use of the dual COX/LOZ

inhibitor for treatment of cancer

NZPERF $3,000

Dr Alesha Smith The range of community

pharmacy service provision

models in New Zealand

NZPERF $7,290

Dr June Tordoff Exploring general practioners’

views on prescribing for older

people living in residential care

NZPERF $3,166

Dr Shyamal Das Can powders for inhalation which

are made by spray-drying be

stabilised? Development of a

physically stable high dose

powder for inhalation for lung

infections by spray-drying

UORG $27,254

Dr Allan Gamble A new target for durg-resistant

tuberculosis: inhibition of

cytochrome bd oxidase with

aurachin D analogues

UORG $36,731

Assoc. Prof. Joel

Tyndall

Developing new agonists for

MAIT cells, new class of anti-

infectives

UORG $56,849

Dr Andrea Vernall Development of fluoresce3nt

ligands for the cannabinoid type

two receptor

UORG $50,000

Dr Dan Wright Towards a revised dosing strategy

for metformin in patients with

impaired kidney function

UORG $35,165

TOTAL GRANTS $414,939

14

Current PhD Students As at 31 December 2014

Hesham Al-Sallami, “Optimising patient care by individualizing dosages of drugs”, with

Professor Stephen Duffull, Associate Professor Natalie Medlicott

Ayodeji Agbowuro, “Design, synthesis and optimization of chlamydia trachomatis

protease inhibitors”, with Associate Professor Joel Tyndall, Dr Allan Gamble

Nagham Ailabouni, “De-prescribing discontinuation of unnecessary medicines in frail

older people in New Zealand”, with Dr June Tordoff, Associate Professor Derelie Magin

(General Practice), Dr Prasad Nishtala

Piyanan Assawasuwannakit, “How patient compliance impacts on drug

pharmacokinetics and pharmacodynamics”, with Associate Professor Rhiannon Braund,

Professor Stephen Duffull

Hanisah Azhari, “Modified cubosomes for drug delivery to the brain”, with Dr Shakila

Rizwan, Professor Ben Boyd (Monash), Professor Sarah Hook

Sharan Bobbala, “Sustained release formulations as therapeutic cancer vaccines”, with

Professor Sarah Hook, Dr Arlene McDowell

Jasper Chui, “Formulation of peptide fertility control agents for the brushtail possum in

New Zealand”, Dr Arlene McDowell, Professor Ian Tucker, and Dr Bernie McLeod (ex

AgResearch) Under Examination

Anna Cooper, “Development of fluorescent ligands for the type 2 cannabinoid receptors”,

with Dr Andrea Vernall, Professor Sarah Hook, Associate Professor Joel Tyndall

Sumit Dadhwal, “Polymersomes: a contemporary method of targeted drug delivery

against cancer”, with Dr Allan Gamble, Professor Sarah Hook

Feifei Feng, “Delivering drugs through the blood brain barrier”, with Professor Ian Tucker,

Associate Professor Paul Fawcett

Paulina Guzman Fuhrur, “Stablisation of protein drugs in phospholipid delivery systems”,

with Associate Professor Natalie Medlicott, and Dr Stefania Baldursdottir and Professor

Thomas Rades (University of Copenhagen) Under Examination

Bhuvan K.C., “Medicines, tourism and healthcare: an investigation into a pharmacist led

travel health service and improved access to medicines in Western Nepal”, with Dr Susan

Heydon, Professor Pauline Norris

Kan Kaneko, “Development and characterization of oral alpha-galactosylceramide

liposomal formulation for use in atopy”, with Professor Sarah Hook, Dr Arlene McDowell

15

Shirley Keown, “Prescription medicines use among Maori in Gisborne: equity and access”,

with Professor Pauline Norris, and Dr Simon Horsburgh (Preventive & Social Medicine)

Kathrin Kramer, “Bio-conjugate approaches for improved adjuvant vaccines”, with Dr

Greg Walker, and Dr Sarah Young (Anatomy)

Arnold Lee, “pH responsive block copolymer vesicles as versatile carriers for cancer

therapy and vaccination, with Professor Sarah Hook, Dr Allan Gamble

Pei Teng (May) Mah, “Imaging of solid dosage forms”, with Dr Olaf Bork, and Dr Clare

Strachan (University of Helsinki), and Professor Thomas Rades (University of Copenhagen)

Under Examination

Andrew McLaughlin, “Development of controlled release devices for the local delivery of

neurogenerative drugs to the brain for the treatment of stroke”, with Dr Greg Walker, and Dr

Andrew Clarkson (Anatomy)

Siddharth Matikonda, “Tumour targeted prodrugs”, with Dr Allan Gamble, Professor

Sarah Hook

Shamin Mohd Saffian, “The dose individualization of dabigatran”, with Dr Dan Wright,

Professor Stephen Duffull, Dr Paul Chin (Christchurch School of Medicine)

Mohammad Momin, “Spray dried powder particles of multidrug combination for treating

multidrug resistant tuberculosis”, with Dr Shyamal Das, Professor Ian Tucker, Associate

Professor Natalie Medlicott

Younus Mohammad, “Endogenous lipid carriers for drug delivery to the brain”, with Dr

Shakila Rizwan, Dr Andrew Clarkson (Anatomy), Professor Ben Boyd (Monash)

Himang Mujoo, “Use of bilosomes to deliver drugs across the blood brain barrier”, with

Professor Ian Tucker, Associate Professor John Reynolds (Anatomy)

Patti Napier, “Investigation of the potential of advanced roles for New Zealand pharmacy

technicians”, with Associate Professor Rhiannon Braund, Professor Pauline Norris

Sujita Narayan, “Preventative medicines use in older people”, with Dr Prasad Nishtala, Dr

June Tordoff

Henry Ndukwe, “The impact of sedative and anticholinergic load on health utilisation in older

people”, with Dr Prasad Nishtala, Dr June Tordoff, and Dr Ting Wang (Maths & Statistics)

Shan Pan, “Development of a population PKPD model for methotrexate and methotrexate

polyglutamates in red blood cells”, with Professor Stephen Duffull, Professor Lisa Stamp

(Medicine), Dr Julia Korell (Model Answers)

Mohammed Salahudeen, “Anticholinergic indices for commonly prescribed medicines”, with

Dr Prasad Nishtala, Professor Stephen Duffull

16

Emma Salis, “Insulin pharmacokinetics and pharmacodynamics (PKPD) in paediatrics and

neonates”, with Associate Professor Natalie Medlicott, Associate Professor David Reith

(SDHB)

Vittal Shivva, “Development of population pharmacokinetic model for ketones”, with Professor

Stephen Duffull, Professor Ian Tucker

Vanda Symon, “Fact and fiction: Communicating science through the crime fiction of Ngaio

Marsh”, with Associate Professor Natalie Medlicott, Dr Susan Heydon, Professor Warwick

Duncan (Oral Sciences)

James Windle, “Learning and assessment connections occurring between the undergraduate

years of the Otago BPharm degree and pre-registration internship, a longitudinal study”, with

Professor Ian Tucker, and Professor Jeffrey Smith (University College of Education), and

Professor Rachel Spronken-Smith (HEDC)

Thi Hong Hanh Vu, “Preparation of rutin containing liposome for oral and evaluation

antioxidation – effect for inflammation liver in vivo”, with Dr Arlene McDowell, Professor

Sarah Hook

Sasi Yarragudi, “Intranasal muco adhesive vesicular systems of neuropeptides for brain-

targetting”, with Dr Shakila Rizwan, Dr Andrew Clarkson (Anatomy), Dr Greg Walker

Bettina Zadehvakili, “Design, synthesis and structure-activity relationshps of some novel

glutathione peroxiodase mimics”, with Associate Professor Paul Fawcett, Dr Gregory Giles

(Pharmacology)

Farrukh Zeeshan, “Investigating protein stabilization in controlled release lipid matrices”, with

Associate Professor Natalie Medlicott, Associate Professor Lene Jorgensen (University of

Copenhagen) – Under Examination

17

BPharm Honours Programme The School re-introduced its Bachelor of Pharmacy Honours (BPharm (Hons)) Programme

for the 2015 academic year, with Honours’ students beginning their research project

(PHCY480) in early November 2014.

All together 33 students from third year of the undergraduate pharmacy programme applied

for entry to the Honour’s programme. Students are selected based upon their GPA up to

and including first semester P3, research experience and interest perceived by their cover

letter and student-teacher interviews, and the availability of preferred research projects.

11 places were offered in the programme. Although the minimum allowable entry grade is a

GPA of B+, most students who entered the programme have a minimum GPA of A.

All students received scholarships to cover the 10-week research period over the summer

between years 3 and 4 (PHCY480). The School is grateful for financial support from a range

of funders as shown below.

Although students are also eligible to join the programme and self-fund their living expenses

over this period, this year there were sufficient scholarships to cover available projects.

Ultimately places were limited by the number of available projects.

Honours Students 2014/15

Philip Arnold

Project: The chemical synthesis and secondary structure of hemopressin analogues as

cannabinoid receptor antagonists.

Supervised by Dr Andrea Vernall

Sponsored by Fred Fastier Trust

Jamie (Kit Yue) Chan

Project: Cationic role of resident mast cells in ischemia reperfusion induced (IRI) kidney

injury.

Supervised by Dr Vishal Diwan


Lily Chen

Project: High dose drug delivery to the lung by engineering drug powders using spray drying

technique

Supervised by Dr Shyamal Das

Sponsored by Douglas Pharmaceuticals

Nalini Ganaeswaren

Project: Drug delivery to the lung - the influence of lung surfactants on dissolution of drugs.

Supervised by Dr Shyamal Das


18

Yen Qi Hew

Project: Optimised formulations of indomethacin.

Supervised by Dr Dorothy Saville

Sponsored by the Christina White Trust

Ha-Lam Jeong

Project: Medicines use amongst people with diabetes

Supervised by Prof. Pauline Norris and Dr Alesha Smith

Sponsored by NZPERF

Liang Kooi Kok

Project: Enzyme inhibitors from cabbage as drugs for inflammatory disease.

Supervised by Assoc. Prof. Joel Tyndall and Dr Allan Gamble


Isabelle Kuan

Project: Model-based estimation of glomerular filtration rate

Supervised by Dr Dan Wright and Prof. Steve Duffull

Sponsored by NZPERF

Catherine Ross

Project: pH responsive delivery of vaccines

Supervised by Prof. Sarah Hook

Sponsored by the School of Pharmacy

Wei Kiet Tey

Project: Interaction of surface modified nano-carriers with immortalized human endothelial

cells

Supervised by Dr Shakila Rizwan

Sponsored by School of Pharmacy Research Committee

Fang Juinn Yu

Project: Optimising the use of vitamin D supplementation in pregnant women and their

infants

Supervised by Mr Hesham Al-Sallami

Sponsored by NZPERF

19

Publications – Journal D1 – JOURNAL, RESEARCH ARTICLE

Aaltonen, K., Miettinen, J., Airio, I., Martikainen, J.E., Saastamoinen, L.K., Bell,

J.S., Hartikainen, S., Norris, P. Cost-related barriers to use of health services and

prescription medicines in Finland: a cross-sectional survey. European Journal of Public Health,

1-5, Nov (2014)

Al-Sallami, H.S., Medlicott, N.J. Investigation of an anti-activated factor X (anti-Xa)

assay for the quantification of enoxaparin in human plasma. Journal of Pharmacy &

Pharmacology, 67(2), 209-214 (2014)

Allegaert, K., Olkkola, K.T., Owens, K.H., Van de Velde, M., de Maat, M.M., Anderson, B.J.,

PACIA study group. Covariates of intravenous paracetamol pharmacokinetics in adults.

Anesthesiology, 14(77), 1-11 (2014)

Alrakaf, S., Abdelmageed, A., Kiersma, M., Coulman, S.A., John, D.N., Tordoff, J.,

Anderson, C., Noreddin, A., Sainsbury, E., Rose, G., Smith, L. An international validation

study of two achievement goal measures in a pharmacy education context. Advances in

Medical Education and Practice, 5, 339-345 (2014)

Anwar, M., Norris, P., Green, J., Au, S, Li, G., Ma, M., Prentice, R., Shum, A.,

Siaw, L.-A., Yoo, S., Zhang, S. Pharmacy students' use of and beliefs about traditional

healthcare. Journal of Immigrant & Minority Health, DOI 10.1007/s10903-014-0013-z April

(2014)

Bagge, M., Norris, P., Heydon, S., Tordoff, J. Older people’s experiences of medicine

changes on leaving hospital. Research in Social & Administrative Pharmacy, 10, 791-800 (2014)

Braund, R., Coulter, C., Bodington, A.J., Giles, L.M., Greig, A-M., Heaslip, L.J.,

Marshall, B.J. Drug related problems identified by community pharmacists on hospital

discharge prescriptions in New Zealand. International Journal of Clinical Pharmacy, 36, 498-502

(2014)

Dew, K., Chamberlain, K., Hodgetts, D., Norris, P., Radley, A., Gabe, J. Home as a hybrid

centre of medication practice. Sociology of Health and Illness, 36(1), 28-43 (2014)

Dickerhof, N., Magon, N.J., Tyndall, J.D.A., Kettle, A.J., Hampton, M.B. Potent inhibition of

macrophage migration inhibitory factor (MIF) by myeloperoxidase-dependent oxidation of

epicatechins. Biochemical Journal, 462, 303-314 (2014)

Even, M.-P., Young, K., Winter, G., Hook, S., Engert, J. In vivo investigation of twin-screw

extruded lipid implants for vaccine delivery. European Journal of Pharmaceutics &

Biopharmaceutics, 87(2), 338-346 (2014)

Feltrin, K.L., Brennan, I.M., Rades, T., Horowitz, M., Feinle-Bisset, C. Acute oral

administration of lauric acid reduces energy intake in healthy males. E-SPEN Journal, 9, e-69-

e75 (2014)

20

Feng, B., Zhu, H., Guan, J., Zhao, L., Gu, J., Yin, L., Fawcett, J.P., Liu, W. A rapid and

sensitive UFLC-MS/MS method for the simultaneous determination of gentiopicroside and

swertiamarin in rat plasma and its application in pharmacokinetics. Journal of Pharmacy &

Pharmacology, 66(10), 1369-1376 (2014)

Fussell, A.L., Mah, P.T., Offerhaus, H., Niemi, S.-M., Salonen, J., Santos, H.A., Strachan, C.

Coherent anti-Stokes Raman scattering (CARS) microscopy driving the future of loaded

mesoporous silica imaging. Acta Biomaterialia, 10, 4870-4877 (2014)

Gerard, K., Martinelli, M., Latter, S., Smith, A., Blenkinsopp, A. Patients' valuation of the

prescribing nurse in primary care: A discrete choice experiment. Health Expectations. doi:

10.1111/hex.12193 (2014)

Gheewala, P.A., Peterson, G.M., Curtain, C.M., Nishtala, P.S., Hannan, P.J., Castelino, R.L.

Impact of the pharmacist medication review services on drug-related problems and

potentially inappropriate prescribing of renally cleared medications in residents of aged care

facilities. Drugs & Aging, DOI 10.1007/s40266-014-0208-y - online 4 September (2014)

Green, J. The effect of English proficiency and ethnicity on academic performance and

progress. Advances in Health Science Education, DOI 10.1007/s10459-014-9523-7 – 3 July

(2014)

Green, J.A., Hohmann, C., Lister, K., Albertyn, R., Bradshaw, R., Johnson, C. Implicit and

explicit attitudes towards conventional and complementary and alternative medicine

treatments: Introduction of an Implicit Association Test. Journal of Health Psychology, DOI:

10.1177/1359105314542818 (2014)

Grohganz, H., Priemel, P., Loebmann, K., Hagner Nielsen, L., Laitinen, R., Mullertz, A.,

Van den Mooter, G., Rades, T. Refining stability and dissolution rate of amorphous drug

formulations. Expert opinion, Drug Delivery, 1742-5247 (2014)

Gulati, A., Isbister, G.K., Duffull, S.B. Scale reduction of a systems coagulation model

with an application to modelling pharmacokinetic-pharmacodynamic data. CPT,

Pharmacometrics Systems Pharmacology, 3, e90 doi:10.1038/psp.2013.67 (2014)

Hanning, S.M., Kieser, J.A., Ferguson, M.M., Reid, M., Medlicott, N.J. The use of lithium

as a marker for the retention of liquids in the oral cavity after rinsing. Clinical Oral

Investigations, 18, 1533-1537 (2014)

Hatah, E., Tordoff, J., Duffull, S.B., Braund, R. Pharmacists' performance of clinical

interventions during adherence support medication reviews. Research in Social &

Administrative Pharmacy, 10, 185-194 (2014)

Hatah, E., Tordoff, J., Duffull, S.D., Cameron, C., Braund, R. Retrospective

examination of selected outcomes of Medicines Use Review (MUR) services in New

Zealand. International Journal of Clinical Pharmacy, 36(3), 503-512 (2014)

21

Horsburgh, S., Norris, P., Becket, G., Arroll, B., Crampton, P., Cumming, J., Keown, S.,

Herbison, P. Allopurinol use in a New Zealand population: prevalence and adherence.

Rheumatol International, 34, 963-970 (2014)

Hubert, M., Larsen, D.S., Hayman, C.M., Rades, T., Hook, S. Physicochemical

characterization of synthetic phosphatidylinositol dimannosides and analogues in binary

systems with phosphatidylcholine. Molecular Pharmaceutics, 11, 913-921 (2014)

Knox, L.T., Jing, Y., Collie, N.D., Zhang, H., Liu, P. Effects of acute phencyclidine

administration on arginine metabolism in the hippocampus and prefrontal cortex in rats.

Neuropharmacology, 81, 195-205 (2014)

Liu, P., Fleete, M. S., Jing, Y., Collie, N. D., Curtis, M.A., Waldvogel, H. J., Faull, R.l.M.,

Abraham, W.C., Zhang, H. Altered arginine metabolism in Alzheimer’s disease brains.

Neurobiology of Aging, 35(9), 1992-2003 (2014)

Mah, P.T., Laaksonen, T., Rades, T., Aaltonen, J., Peltonen, L., Strachan, C.J. Unravelling the

relationship between degree of disorder and the dissolution behavior of milled

glibenclamide. Molecular Pharmaceutics, 11(1), 234-242 (2014)

McDowell, A., Fothergill, J.A., Khan, A., Medlicott, N.J. A cyclodextrin formulation to

improve use of the anaesthetic tribromoethanol (Avertin®). Theme Issue of the Journal of

Pharmacy and BioAllied Sciences 6: 16-21 (2014)

Monk, B.C., Tomasiak, T.M., Keniya, M.V., Huschmann, F.U., Tyndall, J.D.A., O'Connell,

III, J.D., Cannon, R.D., Stroud, R.M. Architecture of a single membrane spanning cytochrome

P450 suggests constraints that orient the catalytic domain relative to a bilayer. PNAS,

111(10), 3865-3870 (2014)

Mooranian, A., Negrulj, R., Chen-Tan, N., Al-Sallami, H.S., Fang, Z., Mukkur, T., Mikov,

M., Golocorbin-Kon, S., Fakhoury, M., Arfuso, F., Al-Salami, H. Novel artificial cell

microencapsulation of a complex gliclazide-deoxycholic bile acid formulation: a

characterization study. Drug Design Development and Therapy, 8, 1003-1012 (2014)

Mooranian, A., Negrulj, R., Chen-Tan, N., Al-Sallami, H.S., Fang, Z., Mukkur, T., Mikov,

M., Golocorbin-Kon, S., Fakhoury, M., Watts, G.F., Matthews, V., Arfuso, F., Al-Salami, H.

Microencapsulation as a novel delivery method for the potential antidiabetic drug, Probucol.

Drug Design, Development & Therapy, 8, 1221-1230 (2014)

Ndukwe, H.C., Tordoff, J.M., Wang, T., Nishtala, P.S. Psychotropic medicine

utilization in older people in New Zealand from 2005 to 2013. Drugs & Aging, 31(10), 755-

768 (2014)

Neumann, S., Burket, K., Kemp, R., Rades, T., Dunbar, R., Hook, S. Activation of the

NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants. Immunol Cell Biol,

92, 535-542 (2014)

Nishtala, P.S., Bagge, M.L., Campbell, A.J., Tordoff, J.M. Potentially inappropriate

medicines in a cohort of community-dwelling older people in New Zealand. Geriatrics &

Gerontology International. 14, 89-93 (2014)

22

Nishtala, P.S., Narayan, S.W., Wang, T., Hilmer, S.N. Associations of drug burden index

with falls, general practitioner visits, and mortality in older people. Pharmacoepidemiology &

Drug Safety, 23(7), 753-758 (2014)

Nishtala, P.S., Salahudeen, M.S. Temporal trends in polypharmacy and

hyperpolypharmacy in older New Zealanders over a 9-year period: 2005-2013. Gerontology,

doi: 10.1159/000368191 (2014)

Niyomnaitham, S., Page, A., La Caze, A., Whitfield, K., Smith, A.J. Utilisation trends of

rosiglitazone and pioglitazone in Australia before and after safety warnings. BMC Health

Services Research, 14(151), 1-7 (2014)

Noor, Z.M., Smith, A.J., Smith, S.S., Nissen, L.M. A study protocol: a community

pharmacy-based intervention for improving the management of sleep disorders in the

community settings. BMC Health Services Research, 14(74), 1-8 (2014)

Norris, P., Horsburgh, S., Becket, G., Keown, S., Arroll, B., Lovelock, K., Crampton, P.,

Cumming, J., Herbison, P. Equity in statin use in New Zealand. Journal of Primary Health Care,

6(1), 17-22 (2014)

Norris, P., Horsburgh, S., Sides, G., Ram, S., Fraser, J. Geographical access to community

pharmacies in New Zealand. Health & Place, 29, 140-145 (2014)

Nyberg, J., Bazzoli, C., Ogungbenro, K., Aliev, A., Leonov, S., Duffull, S.B., Hooker, A.C.,

Metre, F. Methods and software tools for design evaluation in population pharmacokinetics-

pharmacodynamics. British Journal of Clinical Pharmacology, doi. 10.1111/bcp.12352 (2014)

Owens, K.H., Murphy, P.G.M., Medlicott, N.J., Kennedy, J., Zacharias, M., Curran, N.,

Sreebhavan, S., Thompson-Fawcett, M., Reith, D.M. Population pharmacokinetics of

intravenous acetaminophen and its metabolites in major surgical patients. Journal of

Pharmacokinetics and Pharmacodynamics, 41, 211-221 (2014)

Pan, S., Stamp, L. K., Duffull, S.B., Barclay, M. L., Dalrymple, J. M., Drake, J., Zhang, M.,

Korell, J. Assessment of the relationship between methotrexate polyglutamates in red

blood cells and clinical response in patients commencing methotrexate for rheumatoid

arthritis. Clinical Pharmacokinetics, DOI 10.1007/s40262-014-0179-5 (2014)

Putt, T.L., Duffull, S.B., Schollum, J.B.W., Walker, R.J. GFR may not accurately predict

aspects of proximal tubule drug handling. European Journal of Clinical Pharmacology, 70(10),

1221-1226 (2014)

Rattanapak, T., Birchall, J., Young, K., Kubo, A., Fujimori, S., Ishii, M., Hook, S.

Dynamic visualization of dendritic cell-antigen interactions in the skin following

transcutaneous immunization Submitted to Plos One, 9(2), e89503 (2014)

Roberts, R.L., Wallace, M.C., Wright, D.F.B., Dalbeth, N., Highton, J., Jones, P.B., Gow,

P.J., Stamp, L.K., Harrison, A.A., Merriman, T.R. The Frequency of CYP2C9 polymorphisms

in Polynesians and potential relevance to management of gout with benzbromarone. Joint

Bone Spine, 81, 160-163 (2014)

23

Salahudeen, M.S., Duffull, S.B., Nishtala, P.S. Impact of anticholinergic discontinuation

on cognitive outcomes in older people: a systematic review. Drugs Aging, 31, 185-192 (2014)

Sharma, S., KC, Bhuvan, Alrasheedy, A.A., Kaundinnyayana, A., Khanal, A. Impact of

community pharmacy-based educational intervention on patients with hypertension in

Western Nepal. Australasian Medical Journal, 7(7), 304-313 (2014)

Sherwin, C.M.T., Medlicott, N.J., Reith, D.M., Broadbent, R.S. Intravenous drug delivery in

neonates: Lessons learnt. Archives of Disease in Childhood, 99(6), 590-594 (2014)

Shi, M., Yang, Y., Sun, Y., Cheng, L., Zhao, S., Xu, H., Fawcett, J.P., Sun, X., Gu, J.

Pharmacokinetic study of calenduloside E and its active metabolite oleanolic acid in beagle

dog using liquid chromatography-tandem mass spectrometry. Journal of Chromatography B,

951-952, 129-134 (2104)

Shivva, V., Korell, J.K., Tucker, I.G., Duffull, S.B. Choice of parameterisation affects

identifiability for population models. Journal of Pharmacokinetics & Pharmacodynamics, (41) 81-

86 (2014)

Stamp, L.K., Merriman, T.R., Barclay, M.L., Singh, J.A., Roberts, R.L., Wright, D.F.B.,

Dalbeth, N. Impaired response or insufficient dosage? Examining the potential causes of

“inadequate response” to allopurinol in the treatment of gout. Seminars in Arthritis &

Rheumatism, 44(2), 170-174 (2014)

Vernall, A.J., Hill, S.J., Kellam, B. The evolving small-molecule fluorescent-conjugate

toolbox for Class A GPCRs. British Journal of Pharmacology, 171(5), 1073-1084 (2014)

Wang, H., Sun, Y., Guo, W., Fang, C., Fawcett, J.P., Li, W., Gao, Y., Yang, Y., Gu, J.

Determination of a deuterohemin–peptide conjugate in rat plasma by liquid

chromatography-tandem mass spectrometry and application to a preclinical pharmacokinetic

study. Journal of Pharmaceutical and Biomedical Analysis, 98, 401-406 (2014)

Wu, X.-J., Zhang, M.-L., Cui, X.-Y., Fawcett, J.P., Gu, J.-K. Comparative pharmacokinetics

and the bioavailability of escin Ib and isoescin Ib following the administration of escin, pure

escin Ib and isoescin Ib in rats. Journal of Ethnopharmacology, 151, 839-845 (2014)

Yang, L., Feng, F., Fawcett, J.P., Tucker, I.G. Kinetic and equilibrium studies of bile

salt-liposome interactions. Journal of Liposome Research, 1532-2394 (2014)

24

Conference Presentations VERBAL PRESENTATIONS

Aaltonen, K.A., Horsburgh, S., Bell, J.S., Hartikainen, S., Norris, P. Out-of-pocket costs for

medicines among community-dwelling older people in New Zealand. Proceedings of the

International Social Pharmacy Workshop, Boston, USA, 5-8 August, 2014 Research in Social and

Administrative Pharmacy, 10, e1-e64 (2014)

Al-Sallami, H.S. Integrating a PKPD computer simulation in the BPharm course.

Proceedings of the Population Approach Group Australia and New Zealand, Dunedin, New

Zealand, 29-31 January, 2014

Al-Sallami, H. Integrating a pharmacokinetic-pharmacodynamic computer simulation in the

BPharm course. Australasian Society of Clinical and Experimental Pharmacologists and

Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New

Zealand, 27-29 August 2014

Assawasuwannakit, P., Braund, R., Duffull, S.B. Development of a criterion to

quantify forgiveness. Proceedings of the Population Approach Group Australia and New Zealand,

Dunedin, New Zealand, 29-31 January, 2014

Assawasuwannakit, P. Quantification of the forgiveness of drugs to imperfect adherence.

Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand

Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand, 27-29 August,

2014

Ballantyne, P.J., Norris, P., Thomson, W.M. Medication use trajectories from age 26 to 38

in a representative birth cohort from Dunedin, New Zealand. Proceedings of the International

Social Pharmacy Workshop, Boston, USA, 5-8 August, 2014 Research in Social and


Bobbala, S., Tamboli, V., Young, K., McDowell, A., Mitra, A.K., Hook, S. Novel

injectable pentablock copolymer-based thermoresponsive hydrogels for sustained vaccine

delivery. Proceedings of the 5th FIP Pharmaceutical Sciences World Congress, Melbourne,

Australia, 13-16 April, 2014

Bobbala, S., Tamboli, V., McDowell, A., Mitra, A.K., Hook, S. Movel injectable

pentablock copolymer hydrogels for sustained release cancer vaccines. Proceedings of the D4:

Devices for Diagnostics and Drug Delivery meeting, Dunedin, NZ, 26-27 November, 2014

Braund, R., Allison, N. Comparison of self-reported medicine use with the

pharmaceutical claims database in patients with osteoarthritis. Proceedings of the International

Social Pharmacy Workshop, Boston, USA, 5-8 August, 2014 Research in Social and


Cannon, R.C., Sagatova, A., Tomasiak, T.M., Keniya, M.V., Huschmann, F.U., O’Connell

III, J.D., Luckner, S.R., Krause, K., Finer-Moore, J., Stroud, R.M., Tyndall, J.D.A., Monk,

25

B.C., American Society for Microbiology Conference on Candida and Candidiasis, New Orleans,

USA, 26-30 March 2014

Chiu, J., Radunskaya, A., Tucker, I., McDowell, A. Understanding the accumulation of

polymeric nanoparticles at the cell surface. Proceedings of the D4: Devices for Diagnostics and

Drug Delivery meeting, Dunedin, NZ, 26-27 November, 2014

Das, S., Stewart, P., Shi, J., Morton, D. Understanding the de-aggl omeration kinetics of dry

coated powders. Proceedings of the 5th FIP Pharmaceutical Sciences World Congress, Melbourne,


Das, S. Pulmonary delivery of spray-dried powders using dry powder inhalers. Proceedings

of the D4: Devices for Diagnostics and Drug Delivery meeting, Dunedin, NZ, 26-27 November,

2014

Green, J.A., Anwar, M., Norris, P. Do positive attitudes to pharmacists mean that

pharmacies are the first port of call for minor illnesses? Proceedings of the International Social

Pharmacy Workshop, Boston, USA, 5-8 August, 2014 Research in Social and Administrative

Pharmacy, 10, e1-e64 (2014)

Harper, T., Duffull S.B. SimPharm v2.0: A patient-simulation based clinical pharmacology

teaching tool. Proceedings of the Population Approach Group Australia and New Zealand,

Dunedin, New Zealand, 29-31 January, 2014

Heydon, S. Amchi medicine in Khumbu: An outsider’s perspective. Proceedings of the

Himalayan Studies Conference at Yale University, Connecticut, USA, 14-16 March, 2014

Heydon, S., Chua, Y.M., Jin, B., Khambete, S.A., Mastapar, M.A., Md Jazam, R., Ngiam, H.C.,

Sharma, P., Yip, L.F. Acculturation of international students studying pharmacy. Proceedings of

the International Social Pharmacy Workshop, Boston, USA, 5-8 August, 2014 Research in Social

and Administrative Pharmacy, 10, e1-e64 (2014)

KC, B, Heydon, S., Norris, P. Access to and use of medicines in a rural Nepalese village:

lessons for the essential medicines programme, 7th OIHRN conference, Dunedin, NZ,

12 November 2014

Napier, P., Braund, R., Norris, P. Would an advanced technicians’ role facilitate

pharmacists moving to a more clinically focused role? – A New Zealand perspective.

Proceedings of the International Social Pharmacy Workshop, Boston, USA, 5-8 August, 2014

Research in Social and Administrative Pharmacy, 10, e1-e64 (2014)

Nishtala, P., Salahudeen, S., Narayan, S.W. A comparison of anticholinergic risk

scales and associations to adverse health outcomes in older people. Proceedings of the 5th FIP

Pharmaceutical Sciences World Congress, Melbourne, Australia, 13-16 April, 2014

Norris, P., Tordoff, J., Laxman, K., McIntosh, B., Crampton, P. Consequences of

prescription charges for low income people. Proceedings of the International Social Pharmacy

Workshop, Boston, USA, 5-8 August, 2014 Research in Social and Administrative Pharmacy, 10,

e1-e64 (2014)

26

Pan, S., Korell, J., Stamp, L., Duffull, S. Simplification of a pharmacokinetic model for red

blood cell methotrexate disposition. Proceedings of the Population Approach Group Australia

and New Zealand, Dunedin, New Zealand, 29-31 January, 2014

Pan, S. Assessment of the relationship between methotrexate polyglutamates in red blood cells

and clinical response in rheumatoid arthritis. Australasian Society of Clinical and Experimental

Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting,

Queenstown, New Zealand, 27-29 August, 2014

Robinson, A., Ussher, J., Medlicott, N. Novel methods for the rapid identification and

susceptibility testing of blood culture isolates. Proceedings of the D4: Devices for Diagnostics

and Drug Delivery meeting, Dunedin, NZ, 26-27 November, 2014

Saffian, S.M., Wright, D.F.B., Roberts, R., Tait, R.C., Black, L., Lund, K., Duffull, S.B.

The influence of CYP2C9 and VKORC1 genotype on the predictive performance of a

Bayesian forecasting method for warfarin therapy. Proceedings of the Population Approach

Group Australia and New Zealand, Dunedin, New Zealand, 29-31 January, 2014

Salahudeen, M.S., Nishtala, P.S., Duffull, S.B. Estimating the relative potencies of an

anticholinergic medicine: A methodological view point. Proceedings of the Population Approach

Group Australia and New Zealand, Dunedin, New Zealand, 29-31 January, 2014

Salahudeen, M. Estimation of anticholinergic burden. Australasian Society of Clinical and

Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual

Scientific Meeting, Queenstown, New Zealand, 27-29 August, 2014

Shivva, V., Cox, P., Clarke, K., Tucker, I.G., Duffull, S.B. Population pharmacokinetic

model for D-β-Hydroxybutyrate following ketone monoester ingestion. . Proceedings of the

Population Approach Group Australia and New Zealand, Dunedin, New Zealand, 29-31 January,

2014

Shivva, V. A multiscale systems pharmacology model for pharmacokinetic disposition ketone

monoester and its metabolism products in humans. Australasian Society of Clinical and

Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual

Scientific Meeting, Queenstown, New Zealand, 27-29 August, 2014

Smith, A., Harrison, J., Parkin, L. Pharmacoepidemiology: Opportunities & challenges.

Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand

Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand, 27-29 August,

2014.

Tordoff, J.M., Benner, N-A., Broomfield, L.D., Hamilton, L.J. Jaques, Z.E.,

Kerslake, J.M., Soeteman, C.A., Spittal, J.L., Wilson, H.C., Nishtala, P.S. The

impact of focused teaching sessions on New Zealand pharmacy students’ attitudes to people

suffering from schizophrenia and other mental illnesses. Proceedings of the International Social

Pharmacy Workshop, Boston, USA, 5-8 August, 2014 Research in Social and Administrative

Pharmacy, 10, e1-e64 (2014)

Tyndall, J.D.A., Sagatova, A., Tomasiak, T.M., Keniya, M.V., Huschmann, F.U.,

O’Connell, III. J.D.O., Rodruigez, A., Finer-Moore, J., MacDonald, J.G., Cannon, R.D., Stroud,

27

R.M., Monk, B.C. Structures of the full-length bitopic membrane protein CYP51 from

Saccharomyces cerevisiae provide insight into substrate and drug binding and mutations

affecting antifungal susceptibility. Proceedings of the 29th Biennial Conference of the Society of

Crystallographers in Australia and New Zealand (CRYSTAL 29), Queensland, Australia, 22-24

April, 2014

Tyndall, J.D.A. Multiple binding modes of isothiocyanate inhibitors of macrophage

migration inhibitory factor define structure activity relationships. New Zealand Structural

Biology meeting, Hanmer Springs, New Zealand, 30 June-2 July, 2014

Tyndall, J.D.A. Structural resolution of the full-length bitopic membrane protein CYPS1

mono-oxygenase from Saccharomyces cerevisiae; substrate, drug binding and mutations

affecting antifungal susceptibility. Oxygen Theme Meeting, University of Otago Christchurch,

Christchurch, New Zealand, 3-4 July, 2014

Utufua, S. (2014). Promethazine use in children under two. In C. Matthewson, M.

Taumoepeau, & I. Iati (Eds.), Proceedings of the Pacific Postgraduate Symposium: Pacific Voices XI,

(pp. 49). Dunedin, New Zealand: Pacific Islands Centre, University of Otago.

Wright, D. The relationship between fractional urate clearance, renal transporter genotype, and

renal function. Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists

New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand, 27-

29 August, 2014

POSTER PRESENTATIONS

Al-Sallami, H.S., Newall, F., Monagle, P., Ignjatovic, V., Cranswick, N., Duffull, S.

Development of a population PK model of unfractioned heparin in paediatric patients.

Journal of Pharmacokinetics & Pharmacodynamics – an official journal of the International Society

of Pharmcometrics ACoP meeting supplement, Las Vegas, USA, 12-15 October, 2014.

Azhari, H., Boyd, B., Rizwan, S. Influence of the surfactant Tween 80 on aqueous self-

assembly of phytantriol. Proceedings of the 5th FIP Pharmaceutical Sciences World Congress,

Melbourne, Australia, 13-16 April, 2014

Azhari, H., Boyd, B. J., Strauss, M., Rizwan, S. Influence of the surfactant Tween 80 on

aqueous self-assembly of phytantriol. Division of Health Sciences Research Forum: Learning

Different Research Languages, Dunedin, New Zealand, September 2014

Braund, R., Tong, A., Tan, E., Tremblay, L., Stringer, T., Peake, B. Photodegradation of

oseltamivir (Tamiflutm) in aqueous solution. Proceedings of the 5th FIP Pharmaceutical Sciences

World Congress, Melbourne, Australia, 13-16 April, 2014

Das, S., Shi, J., Morton, D., Stewart, P. Use of powder bed tensile strength to explain the

improved de-agglomeration of intensive dry coated salbutamol sulphate using magnesium

stearate. Proceedings of the 5th FIP Pharmaceutical Sciences World Congress, Melbourne,


28

Kaneko, K., McDowell, A., Ishil, Y.R., Hayman, C., Hook, S. A validated LC-MS/MS

method for the quantitation of A-Galactosylceramide incorporation in liposomes.

Proceedings of the 5th FIP Pharmaceutical Sciences World Congress, Melbourne, Australia, 13-16

April, 2014

Kramer, K., Young, S., Walker, G. Development of cleavable antigen-adjuvant conjugates

that are triggered by intracellular glutathione. Proceedings of the D4: Devices for Diagnostics

and Drug Delivery meeting, Dunedin, NZ, 26-27 November, 2014

Lee, A., Gamble, A., Hook, S. Characterisation of PDMS-b-PDMAEMA micelles.

Proceedings of the D4: Devices for Diagnostics and Drug Delivery meeting, Dunedin, NZ, 26-27

November, 2014

Liau, J.J., Kaneko, K., Hook, S., Prestidge, C., Barnes, T. Nanostructured lipid in double

emulsion: multi-compartment system for oral vaccine delivery. Proceedings of the 5th FIP

Pharmaceutical Sciences World Congress, Melbourne, Australia, 13-16 April, 2014

Matikonda, S., Fairhall, J., Gamble, A. Stable and triggerable self-immolative allyloxy

prodrug linker for controlled and tumour-targeted drug delivery. Proceedings of the D4:


McDowell, A. Cell penetrating peptides – is charge important for improved uptake of

nanoparticles? Proceedings of the 41st Controlled Release Society annual meeting, Chicago, USA,

13-16 July, 2014

McLaughlin, A., Berretta, A., Clarkson, A., Walker, G. An alternative solvent system for

electrospinning polycaprolactone. Proceedings of the D4: Devices for Diagnostics and Drug

Delivery meeting, Dunedin, NZ, 26-27 November, 2014

Mohammad, Y., Clarkson, A., Boyd, B., Rizwan, S. Formulation and characterisation of

phytantriol-oleoylethanolamide cubosomes. Proceedings of the D4: Devices for Diagnostics and

Drug Delivery meeting, Dunedin, NZ, 26-27 November, 2014

Mujoo, H., Reynolds, J., Tucker, I.G. Effect of bilayer disruptors on the sensitivity of

liposomes to ultrasound. Proceedings of the 5th FIP Pharmaceutical Sciences World Congress,

Melbourne, Australia, 13-16 April, 2014

Mujoo, H. Liposomes for triggered drug delivery: effect of lipid composition on the

sensitivity of liposomes to 1.1. MHz ultrasound. Proceedings of the 41st Controlled Release

Society annual meeting, Chicago, USA, 13-16 July, 2014

Mujoo, H., Reynolds, J., Tucker, I. Effect of bilayer constituents on the US response of

liposomes. Proceedings of the D4: Devices for Diagnostics and Drug Delivery meeting, Dunedin,

NZ, 26-27 November, 2014

Ndukwe, H., Tordoff, J., Wang, T., Nishtala, P.S. Psychotriopic drug utilisation in older

people in New Zealand from 2005 to 2013. Proceedings of the ASCEPT-MPGPCR Joint Scientific

Meeting, Melbourne, Australia, 7-11 December, 2014

29

Neumann, S., Young, K., Kemp, R., Painter, G., Hook, S. Cyclooxygenase-2 and 5-

lipoxygenase inhibition enhances the efficacy of a long peptide vaccine in treating melanoma

in mice. Proceedings of the Inflammation, Infection and Cancer Keystone Symposia on Molecular

and Cellular Biology, Whistler, British Columbia, Canada, 9-14 March 2014

Pan, S., Korell, J., Stamp, L., Duffull, S. Simplification of a pharmacokinetic model for red

blood cell methotrexate disposition. Journal of Pharmacokinetics & Pharmacodynamics – an

official journal of the International Society of Pharmcometrics ACoP meeting supplement, Las Vegas,

USA, 12-15 October, 2014.

Rizwan, S., Azhari, H., Tey, W.K., Boyd, B. Formulation and characterisation of cationic

cubosomes of phytantriol with cetrimonium bromide (CTAB) or N-[1-(2, 3-

Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride (DOTAP). Proceedings of the D4:


Sagatova, A., Keniya, M., Huschmann, F., Wilbanks, S., Cannon, R., Tyndall, J., Monk, B.

Erg11p structure in a triazole resistant yeast strain. Division of Health Sciences Research Forum:

Learning Different Research Languages, Dunedin, New Zealand, September, 2014

Saville, D. Factors influencing release from enteric coated aspirin tablets. Proceedings of the

5th FIP Pharmaceutical Sciences World Congress, Melbourne, Australia, 13-16 April, 2014

Shirley, S., Hook, S., Kemp, R., Neumann, S. MDSC and their potential role in

therapeutic vaccine formulations. Proceedings of the D4: Devices for Diagnostics and Drug

Delivery meeting, Dunedin, NZ, 26-27 November, 2014

Shivva, V., Cox, P., Clarke, K., Veech, R.L., Tucker, I.G., Duffull, S.B. A population

pharmacokinetic model for Ḍ-β-Hydroxybutyrate following administration of ketone

monoester. Journal of Pharmacokinetics & Pharmacodynamics – an official journal of the

International Society of Pharmcometrics ACoP meeting supplement, Las Vegas, USA, 12-15

October, 2014

Shivva, V., Tucker, I.G., Duffull, S.B. A multiscale systems pharmacology model for

pharmacokinetic disposition of ketone monoester and its metabolism products in human.

Journal of Pharmacokinetics & Pharmacodynamics – an official journal of the International Society

of Pharmcometrics ACoP meeting supplement, Las Vegas, USA, 12-15 October, 2014

Tong A, Tan E, Tremblay L, Stringer T, Peake B, Braund R. Photodegradation of

oseltamivir (tamiflu) in aqueous solution. Proceedings of the 5th FIP Pharmaceutical Sciences

World Congress, Melbourne, Australia, 13-16 April, 2014

Tyndall, J.D.A., Spencer, E.S., Dale, E.J., Gommans, A.L., Rutledge, M.T., Vo, C.T.,

Nakatini, Y., Gamble, A.B., Smith, R.A.J., Wilbanks, S.M., Hampton, M.B. Multipel binding

modes of isothiocyanate inhibitors of macrophage migration inhibitory fact define structure

activity relationships. Proceedings of the 29th Biennial Conference of the Society of

Crystallographers in Australia and New Zealand (CRYSTAL 29), Queensland, Australia, 22-24

April, 2014

Tyndall, J.D.A., Spencer, E.S., Dale, E.J., Gommans, A.L., Rutledge, M.T., Vo, C.T.,

Nakatani, Y., Gamble, A. B., Smith, R.A.J., Wilbanks, S.M., Hampton, M.B. Multiple binding

30

modes of isothiocyanate inhibitors of macrophage migration inhibitory factor define design

strategies. Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand, 25-29

August, 2014

Wright, D.F.B., Duffull, S.B., Merriman, T.R., Barclay, M.L., Stamp, L.K. A population

pharmacokinetic-pharmcodynamic model for allopurinol in patients with gout. Journal of

Pharmacokinetics & Pharmacodynamics – an official journal of the International Society of

Pharmcometrics ACoP meeting supplement, Las Vegas, USA, 12-15 October, 2014

Yarrigudi, S., Walker, G., Clarkson, A., Rizwan, S. Formulation and characterisation of

a novel microparticle system for nose-to-brain drug delivery. Proceedings of the D4: Devices

for Diagnostics and Drug Delivery meeting, Dunedin, NZ, 26-27 November, 2014

Zeeshan, F., Medlicott, M., Jorgensen, L. Conformational stability of proteins in solid

lipid matrices: effect of protein inherent thermal stability. Proceedings of the D4: Devices for

Diagnostics and Drug Delivery meeting, Dunedin, NZ, 26-27 November, 2014

31

Conference Attendance The School is pleased to be able to support staff and postgraduate students to attend

national and international conferences. This is essential to ensure that the academic staff

are abreast of developments in their field, to allow them to network with potential

international collaborators and to provide opportunity to present research data where it

can be peer-reviewed and critically assessed.

PhD students are given a grant-in-aid to attend national and international conferences to

present their PhD research in second and third years of their programme. Support is also

provided by the Division of Health Sciences.

Not all were financially supported by the School

Name Conference name Location Dates

Hesham Al-Sallami Population Approach Group New Zealand

& Australia Dunedin, NZ 29-31 January

Jill

Assawasuwannakit

Population Approach Group New Zealand


Stephen Duffull Population Approach Group New Zealand


Thomas Harper Population Approach Group New Zealand


Shan Pan Population Approach Group New Zealand


Shamin Saffian Population Approach Group New Zealand


Mohammed

Salahudeen

Population Approach Group New Zealand


Vittal Shivva Population Approach Group New Zealand


Dan Wright Population Approach Group New Zealand


Sarah Hook Inflammation, Infection and Cancer Whistler,

Canada 9-14 March

Susan Heydon 3rd ANHS Himalayan Studies Conference Connecticut,

USA 14-16 March

Sharan Bobbala FIP Pharmaceutical Sciences World

Congress

Melbourne,

Australia 13-16 April

Rhiannon Braund FIP Pharmaceutical Sciences World

Congress

Melbourne,


Shyamal Das FIP Pharmaceutical Sciences World

Congress

Melbourne,


Kan Kaneko FIP Pharmaceutical Sciences World

Congress

Melbourne,


32

Himang Mujoo FIP Pharmaceutical Sciences World

Congress

Melbourne,


Prasad Nishtala FIP Pharmaceutical Sciences World

Congress

Melbourne,


Shakila Rizwan FIP Pharmaceutical Sciences World

Congress

Melbourne,


Dorothy Saville FIP Pharmaceutical Sciences World

Congress

Melbourne,


Ian Tucker FIP Pharmaceutical Sciences World

Congress

Melbourne,


Joel Tyndall SCANZ | Crystal 29 Queensland,


Katrin Kramer 12th annual Cancer Immunotherapy (CIMT)

research meeting

Mainz,

Germany 6-8 May

Allan Gamble 15th Tetrahedron Symposium: Challenges in

Bioorganic and Organic Medicinal Chemistry London, UK 24-27 June

Joel Tyndall NZ Structural Biology Conference Hanmer

Springs, NZ 30 June-2 July

Arlene McDowell Controlled Release Society Chicago,

USA 13-16 July

Himang Mujoo Controlled Release Society Chicago,

USA 13-16 July

Rhiannon Braund International Social Pharmacy workshop Boston, USA 5-8 August

James Green International Social Pharmacy workshop Boston, USA 5-8 August

Susan Heydon International Social Pharmacy workshop Boston, USA 5-8 August

Patti Napier International Social Pharmacy workshop Boston, USA 5-8 August

Pauline Norris International Social Pharmacy workshop Boston, USA 5-8 August

June Tordoff International Social Pharmacy workshop Boston, USA 5-8 August

Natalie Medlicott Nordic Rheological Society Annual

Conference

Reykjavik,

Iceland 11-15 August

Hesham Al-Sallami

Queenstown Research Week – Australasian

Society of Clinical and Experimental

Pharmacologists and Toxicologists - NZ

Queenstown,

NZ 24-29 August

Vishal Diwan Queenstown Research Week: Kidney

Biology

Queenstown,

NZ 24-29 August

Joel Tyndall Queenstown Research Week: QMB Queenstown,

NZ 24-29 August

Andrea Vernall Queenstown Research Week – Australasian


Queenstown,

NZ 24-29 August

33

Pharmacologists and Toxicologists – NZ;

and Drug Discovery meetings

Dan Wright

Queenstown Research Week – Australasian


Pharmacologists and Toxicologists - NZ

Queenstown,

NZ 24-29 August

Hesham Al-Sallami New Zealand Hospital Pharmacists’

Association conference (NZHPA)

Wellington,

NZ

5-7

September

Rhiannon Braund New Zealand Hospital Pharmacists’

Association conference (NZHPA)

Wellington,

NZ

5-7

September

Shyamal Das

International Society for Aerosols in

Medicine and Woolcock Institute of Medical

Research

Sydney,

Australia

25-26

September

Hesham Al-Sallami Bay Area PKPD annual meeting

San

Francisco,

USA

9-11 October

Stephen Duffull Bay Area PKPD annual meeting

San

Francisco,

USA

9-11 October

Dan Wright Bay Area PKPD annual meeting

San

Francisco,

USA

9-11 October

Vanda Symon 6th International Conference on Science in

Society

Vancouver,

Canada

10-11

October

Hesham Al-Sallami American Conference on Pharmacometrics

(ACoP)

Las Vegas,

USA

12-15

October

Stephen Duffull American Conference on Pharmacometrics

(ACoP)

Las Vegas,

USA

12-15

October

Shan Pan American Conference on Pharmacometrics

(ACoP)

Las Vegas,

USA

12-15

October

Vittal Shivva American Conference on Pharmacometrics

(ACoP)

Las Vegas,

USA

12-15

October

Dan Wright American Conference on Pharmacometrics

(ACoP)

Las Vegas,

USA

12-15

October

Prasad Nishtala 30th International Conference on

Pharmacoepidemiology

Taipei,

Taiwan

24-27

October

Kan Kaneko American Association of Pharmaceutical

Scientists (AAPS)

San Diego,

USA

2-6

November

Sharan Bobbala American Association of Pharmaceutical

Scientists (AAPS)

San Diego,

USA

2-6

November

Sarah Hook American Association of Pharmaceutical

Scientists (AAPS)

San Diego,

USA

2-6

November

Susan Heydon Combined ASAANZ/AAS conference Queenstown,

NZ 13 November

Sharan Bobbala D4: Devices for Diagnostics and Drug

Delivery Dunedin, NZ

26-27

November

34

Olaf Bork D4: Devices for Diagnostics and Drug


26-27

November

Jasper Chiu D4: Devices for Diagnostics and Drug


26-27

November

Shyamal Das D4: Devices for Diagnostics and Drug


26-27

November

Sarah Hook D4: Devices for Diagnostics and Drug


26-27

November

Arnold Lee D4: Devices for Diagnostics and Drug


26-27

November

Katrin Kramer D4: Devices for Diagnostics and Drug


26-27

November

Siddharth

Matikonda

D4: Devices for Diagnostics and Drug


26-27

November

Arlene McDowell D4: Devices for Diagnostics and Drug


26-27

November

Andrew

McLaughlan



26-27

November

Younus

Mohammad



26-27

November

Himang Mujoo D4: Devices for Diagnostics and Drug


26-27

November

Shakila Rizwan D4: Devices for Diagnostics and Drug


26-27

November

Ian Tucker D4: Devices for Diagnostics and Drug


26-27

November

Greg Walker D4: Devices for Diagnostics and Drug


26-27

November

Sasi Yarragudi D4: Devices for Diagnostics and Drug


26-27

November

Farrukh Zeeshan D4: Devices for Diagnostics and Drug


26-27

November

Henry Ndukwe

Australasian Society of Clinical and

Experimental Pharmacologists and

Toxicologists (ASCEPT)

Melbourne,

Australia

7-11

December

Andrea Vernall



Toxicologists (ASCEPT) and the Molecular

Pharmacology of GPCRs (MPGPCR) joint

meeting

Melbourne,

Australia

7-11

December

Dan Wright



Toxicologists (ASCEPT)

Melbourne,

Australia

7-11

December

35

Seminars In addition to Journal Clubs, the School has a weekly Seminar programme.

Date Speaker Title of presentation

27 January Andrew McLaughlin

PhD 6-month presentation

A controlled release implant for the local

delivery of neurogenerative drugs for the

treatment of stroke

3 February Mudassir Anwar

Final PhD seminar

A prospective exploration of people’s

experiences of and responses to symptoms

in New Zealand and Pakistan

10 February Henry Ndukwe


Utilisation of psychotropic medicines in

older people in New Zealand

17 February Summer student symposium:

Wei Kiet Tey

Understanding the self-assembling behaviour

of cationic phospholipids as a nanoparticle

template for deliverying drugs across the

Blood-brain barrier (BBB)

Matthew Cross

Preparation of low density particles by

spray-drying

Liang Kooi Kok

Investigation of release of the adjuvant and

antigen from lipid and sugar implants

Nalini Ganaeswaren

Cubosomes for delivering drugs across the

blood-brain barrier

Avis Kao and Lei Xia

Electrospun textiles containing bioactives

from wine waste

Collin Zhang

Artificial muscle for evaluating ultrasound

triggered drug delivery systems

Tilley Carroll

What services do NZ community

pharmacies provide?”

Kirsten Allen NZ’s pharmacy heritage

24 February Karen Chen

Summer student

presentation

Identifying new enzyme inhibitors for

inflammatory disease

Leanne Soo

Summer student

presentation

Utilisation of proton pump inhibitors among

older people in New Zealand

3 March

Linda Gilbert and Dr Chris

Walsh

Health Quality & Safety

Commission

Health Literacy and Medication Safety

10 March Prof. Jean-Michel Cardot Department of

Biopharmaceutics and

Pharmaceutical Technology

Universite d’Auvergne. France

IVIVC : understanding the limiting factors in

the development of drugs and formulations

36

17 March Dr Shyamal Das

School of Pharmacy

Pulmonary drug delivery for treating

chronic pulmonary conditions

31 March Ellen Ou

Final PhD presentation

Pre-formulation of antioxidant

phytochemicals from Sonchus oleraceus L.

(pūhā)

7 April Dr Hu Zhang

School of Pharmacy

Development of Biomarkers of Brain Aging

8 April Prof Gu Jingkai

Jilin University, Changchun,

China

Quantitative Mass Spectrometric Analysis

for DMPK Studies: From Small Molecules to

eptides and Proteins

5 May Ms Megan Anakin

College of Education

University of Otago

Practical techniques to spice up your

teaching

12 May Dr Dan Wright

School of Pharmacy

Model-based dosing and beyond

19 May Dr James Ussher

Department of

Microbiology and

Immunology

University of Otago

When the drugs don’t work: MAIT cells and

the control of bacterial infection

9 June Dr Andrea Vernall

School of Pharmacy Fluorescent Probes as Drug Discovery

Tools

16 June Ms Alexandra Springwald,

and Ms Imogen Jenkins

Visiting student researchers

School of Pharmacy

Synthesis of second generation protease

inhibitors targeting the protease in

Chlamydia, HtrA; and

Bio-orthogonal doxorubicin prodrug

activation with trans-cyclooctenol for

tumour-targeted drug delivery

30 June Dr James Green

School of Pharmacy

Research with pictures: RSL 2013

English language screening, implicit attitudes

to medicines and travel photographs

7 July Silke Neumann

Final PhD presentation

Long peptide vaccines for the treatment of

melanoma

14 July Catherine Herd

PHARMAC and the Trans-Pacific

Partnership (TPPA)

21 July Dr Ami Radunskaya

Pomona College

Claremont, California

Clots or Not? Combining mechanistic and

PK-PD models to simulate in vivo clot

formation.

28 July Shamin Saffian


Dose individualisation of dabigatran

28 July Hanisah Azhari


Effect of surface modification on

nanoparticle trafficking across the blood-

brain barrier

4 August Jasper Chiu

Final PhD seminar

Designing oligoarginine associated PECA

nanoparticles for enhanced cellular uptake

11 August Dr Alex McLellan

Microbiology & Immunology

University of Otago

Tumour coagulation factors: a short circuit

to thrombosis

http://en.wikipedia.org/wiki/Changchun

37

18 August Dr Andrew Bahn

Department of Physiology

University of Otago

Uric acid – an ancient beneficial metabolite

turns into a killer of the modern world

25 August Dr Michael Steward

Callaghan Innovation

Wellington

Antibody Therapeutics; Past, Present and

Future

1 September Dr Vishal Diwan

School of Pharmacy

Metabolic syndrome and chronic kidney

disease: Use of well-characterised animal

models to test therapies

8 September Prof. Steve Duffull

School of Pharmacy

Networking and Coagulation

22 September Prof. Pauline Norris

School of Pharmacy

Pharmacy students’ use of traditional

healthcare

6 October James Windle


Relationships between undergraduate and

internship performance of pharmacy

students

6 October Chloe Campbell


Uncharted Territory – The New Zealand

Medicines Information Landscape

3 November Deji Agbowuro


Design and synthesis of Chlamydia

Trachomatis high temperature requirement

protease A Inhibitors

3 November Nagham Ailabouni


De-prescribing in rest homes

10 November Dr Bill Hawkins

Department of Chemistry

University of Otago

One ring to rule them all: the synthesis of

architecturally diverse scaffolds from

cyclopropanes

17 November Dr June Tordoff

School of Pharmacy

RSL in 2014 - and antipsychotic use in

dementia

24 November Farrukh Zeeshan

Final PhD seminar

Protein Structural Stability in Solid Lipids

intended for subcutaneous implants or Oral

Dosage Forms

1 December Siddharth Sai Matikonda


Synthesis of anti-tumour prodrugs for

targeted and controlled release therapy

1 December Sasi Bhushan Yarragudi


Mucoadhesive Microparticles for Nose to

Brain Delivery

4 December Arnold Lee


Environmentally sensitive vehicles for drug

or vaccine delivery against cancer

4 December Younus Mohammed


Targeted drug delivery to brain using

endocannabinoid-based particulate carriers

8 December Dr Leo Schep

National Poisons Centre

Synthetic cannabinoids - then and now

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