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School: Science Programme: Bachelor of Science (B.Sc.) Year : Second Year Semester -IV Course: Organic and Inorganic Chemistry III Course Code:XCH401 Theory: 4 Hrs/Week Max. University Theory Examination: 50 Marks Max. Time for Theory Exam: 3 Hrs Continuous Internal Assessment: 50 Marks Course Objectives 1 To learn a stereochemistry of organic molecules 2 To study an organic reaction mechanisms 3 To study a chemistry of “d” and “f” block elements 4 To study concept of corrosion and passivity Unit Number Details Hours 1 Stereoisomerism Introduction to optical isomerism: Chirality, optical activity and polarimetry, enantiomers, absolute configuration, R/S system nomenclature with wedge and Fischer representation of two chiral centres, erythro, threo, meso-diastereomers with R/S configuration. Baeye’rs strain theory, heat of combustion, cycloalkanes, factors affecting the stability of conformation, Conformation of cyclohexane- equatorial and axialbonds, monosubstituted cyclohexane stability with -CH3 and - C(CH3)3 substitutes. Structures of geometrical isomers of dimethylcyclohexane only. 15 2 Organic Reaction Mechanism Introduction, types of reagentselectrophile, nucleophile and free radical. Types of organic reactions: Addition, Elimination (β-elimination and Hofmann elimination), substitution (aliphatic electrophilic and nucleophilic, aromatic electrophilic) and rearrangement. Mechanism: Aldol condensation, Markovnikov and anti-Markovnikov addition reaction, Saytzeff and Hoffmann elimination, SN 1 and SN 2 reactions, Hofmann rearrangement. 15 3 Chemistry of d-block elements Position of d-block in periodic table, electronic configuration, trends in properties of these elements-size of atoms & ions, reactivity, catalytic 12
Transcript
Page 1: School: Science Programme: Bachelor of Science (B.Sc ...

School: Science Programme: Bachelor of Science (B.Sc.)

Year : Second Year Semester -IV

Course: Organic and Inorganic Chemistry

III

Course Code:XCH401

Theory: 4 Hrs/Week Max. University Theory Examination: 50

Marks

Max. Time for Theory Exam: 3 Hrs Continuous Internal Assessment: 50 Marks

Course Objectives

1 To learn a stereochemistry of organic molecules

2 To study an organic reaction mechanisms

3 To study a chemistry of “d” and “f” block elements

4 To study concept of corrosion and passivity

Unit

Number Details Hours

1 Stereoisomerism

Introduction to optical isomerism: Chirality, optical activity and

polarimetry, enantiomers, absolute configuration, R/S system

nomenclature with wedge and Fischer representation of two chiral centres,

erythro, threo, meso-diastereomers with R/S configuration.

Baeye’rs strain theory, heat of combustion, cycloalkanes, factors affecting

the stability of conformation, Conformation of cyclohexane- equatorial

and axialbonds, monosubstituted cyclohexane stability with -CH3 and -

C(CH3)3 substitutes.

Structures of geometrical isomers of dimethylcyclohexane only.

15

2 Organic Reaction Mechanism

Introduction, types of reagents–electrophile, nucleophile and free radical.

Types of organic reactions: Addition, Elimination (β-elimination and

Hofmann elimination), substitution (aliphatic electrophilic and

nucleophilic, aromatic electrophilic) and rearrangement.

Mechanism: Aldol condensation, Markovnikov and anti-Markovnikov

addition reaction, Saytzeff and Hoffmann elimination, SN1and

SN2reactions, Hofmann rearrangement.

15

3 Chemistry of d-block elements

Position of d-block in periodic table, electronic configuration, trends in

properties of these elements-size of atoms & ions, reactivity, catalytic

12

Page 2: School: Science Programme: Bachelor of Science (B.Sc ...

activity, oxidation state, complex formation ability, colour, magnetic

properties, non-stoichiometry, density, melting & boiling points.

4 The f-block elements

I. The Lanthanoid Series

Electronic Structure, Oxidation States, Extraction from monazite sand

with flow sheet, Uses. Lanthanoid contraction- Definition, causes, effects

of lanthanoid contraction on chemistry of lanthanoids and post lanthanoid

elements. Separation of lanthanoids from one another by solvent

extraction and ion exchange chromatography.

II. The Actinoid series

Electronic structure, position in periodic table, Oxidation states,

Occurrence of actinoids. Preparation of actinoids using- i) Neutron

bombardment ii) Accelerated Projectile bombardment and iii) Heavy ion

bombardment.

10

5 Corrosion and Passivity

I. Corrosion: Definition, Types of corrosion- atmospheric, Immersed,

Mechanism of electrochemical corrosion, Factors affecting corrosion-

position of metal in E. C. S., purity effect of moisture, effect of oxygen,

pH, physical state of metal. Methods of protection of metal from

corrosion- alloy formation, making metal cathodic, controlling external

condition. Coating-galvanising, Tinning, electroplating, metal cladding,

organic coating.

II. Passivity: Definition, Theories of passivity - (i) Oxide film theory (ii)

Gaseous film theory, (iii) Physical film theory, Valence theory, Catalytic

theory, Allotropic theory, electrochemical passivity.

8

Total 60

Course Outcomes

1 Student will be able to understand and explain basics of stereochemistry of organic

molecules

2 Student will be able to explain an organic reaction mechanisms

3 Student will be able to understand and explain chemistry of “d” and “f” block elements

4 Student will be able to explain concept of corrosion and passivity

Page 3: School: Science Programme: Bachelor of Science (B.Sc ...

Resources

Reference Books 1. Organic Chemistry by Clayden, Oxford uni.press.

2. Organic Chemistry by Morrison & Boyd, 6th Edition.

3. A guide book to Mechanism in Organic Chemistry by Peter

Sykes, 6th Edition.

4. Concise Inorganic Chemistry by J.D. Lee, Chapman & Hall 5th

Edn. (1996) ( Page No. 273, 281, 302, 308, 325, 326, 329, 335,

353, 635 – 647).

5. Concepts and Models of Inorganic Chemistry by B. Douglas & D.

Mc. Daniels Alexander Mohan Wiley & sons 3rd Edn. (2007).

6. Inorganic Chemistry Principles of structure & reactivity, By

James Huheey, Keiter, Medhi (Pearson Education).

Page 4: School: Science Programme: Bachelor of Science (B.Sc ...

School: Science Programme: Bachelor of Science (B.Sc.)

Year: Second Year Semester - IV

Course: Organic and Inorganic Chemistry

Laboratory III

Course Code: XCH411

Practical: UG - 4 Hrs/Batch (20 Students) Practical Examination: 25 Marks

Term Work: 25 Marks

Course Objectives

1 To learn an organic compound preparations

2 To study and learn an inorganic synthesis

Sr.

No. Description

1 Organic Preparation: (including Crystallization, MP, TLC)

i) Pthalic anhydride to pthalamide

ii) Glucose to osazone

iii) Acetanilide to p-bromoactanilide

iv) Benzaldehyde to dibenzylidene acetone

v) Benzaldehyde to benzoic acid

2 Inorganic Chemistry Practical (Inorganic Synthesis)

i) Tetramine Cu (II) sulphate.

ii) Hexamine Ni (II) chloride.

iii) Ferrous ammonium sulphate (Mohr’s salt).

iv) Metal-EDTA complex.

Course Outcomes

1 Student able to prepare organic compounds

2 Student able to prepare inorganic compounds

Term Work:

Term Work assessment shall be conducted for the Project, Tutorials and Seminar. Term work

is continuous assessment based on work done, submission of work in the form of

report/journal, timely completion, attendance, and understanding. It should be assessed by

subject teacher of the institute. At the end of the semester, the final grade for a Term Work

shall be assigned based on the performance of the student and is to be submitted to the

University.

Page 5: School: Science Programme: Bachelor of Science (B.Sc ...

Notes

1 The experiments from the regular practical syllabus will be performed (15 Marks).

2 The regular attendance of students during the syllabus practical course will be

monitored and marks will be given accordingly (5 Marks).

3 Good Laboratory Practices (5 Marks)

Practical/Oral/Presentation:

Practical/Oral/Presentation shall be conducted and assessed jointly by internal and external

examiners. The performance in the Practical/Oral/Presentation examination shall be assessed

by at least a pair of examiners appointed as examiners by the University. The examiners will

prepare the mark/grade sheet in the format as specified by the University, authenticate and

seal it. Sealed envelope shall be submitted to the head of the department or authorized person.

Notes

1 One experiment from the regular practical syllabus will be conducted. (Total 15

Marks).

2 Complete laboratory journal/records (05 Marks).

3 Viva-voce (05 Marks).

Page 6: School: Science Programme: Bachelor of Science (B.Sc ...

Year: Second Year

Course: Ecology and Evolution

Teaching

Scheme

(Hrs/Week)

Continuous Internal

L T P C CIA-1 CIA

4 0 - 4 10 20

Max. Time, End Semester Exam (Theory)

Prerequisite Students should have the basic knowledge of Environmental Science

Objectives

1 To study Ecology and Ecosystem

2 To study Environmental Pollution and Control Measures.

3 To study Ecological Conservation

4 To study Origin and Evolution of Life

Unit

Number

1

Introduction to Ecology:

Community Ecology.

and grazing food chains, Food web.

pyramids and Ecological efficiencies.

2

Ecosystem: Introduction. Components and organization of

ecosystem (Terrestrial, aquatic and Artificial). Productivity of Ecosystem: Primary,

Secondary and Net Productivity. B

Phosphorus cycle). Factors effecting ecosystem (Climatic, topographic and Ed

and biotic).

3

Environmental Crisis:

and thermal pollution. Acid Rain, Ozone Depletion, Green House Effect. Nuclear

hazards. Environmental Acts in India. Role of Central and

Boards.

4

Conservation of Ecology:

conservation. Reserves and

Gardens, Seed Banks, Gene Banks, Pollen Banks, DNA Banks,

involved in conservation. Ecological hotspots in India.

5

Evolution: Introduction;

concept: Lamarckism, Darwinism, De

Neo - Darwinism. Speciation:

Parapatric. Process of evolution: Genetic variations in population, Hardy

Weinberg Equilibrium. Evolutionary forces (Genetic Drift: mechanism,

Founder’s effect, bottleneck phenome

changing allele freque

School of Science

B.Sc. Microbiology

Semester: I

Ecology and Evolution Course Code:

Continuous Internal Assessment (CIA) End Semester

Examination

CIA-2 CIA-3 CIA-4 Lab Theory

20 10 10 - 50

End Semester Exam (Theory) - 3Hrs.

Students should have the basic knowledge of Environmental Science

y and Ecosystem

Environmental Pollution and Control Measures.

Ecological Conservation

To study Origin and Evolution of Life

Details

Introduction to Ecology: Introduction, Types of Ecology: Population Ecology,

Community Ecology. Ecological succession - type and pattern. Food chain: Detritus

grazing food chains, Food web. Energy flow through the ecosystem.

ds and Ecological efficiencies.

Introduction. Components and organization of ecosystem. Type of

ecosystem (Terrestrial, aquatic and Artificial). Productivity of Ecosystem: Primary,

Secondary and Net Productivity. Biogeochemical cycles (Nitrogen, Carbon and

Phosphorus cycle). Factors effecting ecosystem (Climatic, topographic and Ed

Environmental Crisis: Definition, sources, effects and control:

and thermal pollution. Acid Rain, Ozone Depletion, Green House Effect. Nuclear

hazards. Environmental Acts in India. Role of Central and State Pollution Control

Conservation of Ecology: Current Practices in Conservation, In

Reserves and National Parks, Germplasm Collections, Botanical

Gardens, Seed Banks, Gene Banks, Pollen Banks, DNA Banks,

involved in conservation. Ecological hotspots in India.

Introduction; Life’s Beginnings: Historical review of evolutionary

concept: Lamarckism, Darwinism, De - Vries theory of Mutation,

Darwinism. Speciation: Modes of speciation - Sympatric, Allopatric and

Process of evolution: Genetic variations in population, Hardy

Weinberg Equilibrium. Evolutionary forces (Genetic Drift: mechanism,

ounder’s effect, bottleneck phenomenon; Role of Migration and Mutation in

changing allele frequencies.)

Pa

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Semester: IV

Course Code: XBO401

End Semester

Examination Total

Lab

- 100

Students should have the basic knowledge of Environmental Science

Hours

Types of Ecology: Population Ecology,

Food chain: Detritus

ergy flow through the ecosystem. Ecological

12 L

ecosystem. Type of

ecosystem (Terrestrial, aquatic and Artificial). Productivity of Ecosystem: Primary,

(Nitrogen, Carbon and

Phosphorus cycle). Factors effecting ecosystem (Climatic, topographic and Edaphic

12 L

, sources, effects and control: Air, water, soil

and thermal pollution. Acid Rain, Ozone Depletion, Green House Effect. Nuclear

State Pollution Control

12 L

Current Practices in Conservation, In-situ and Ex situ

Germplasm Collections, Botanical

National agencies

12 L

Life’s Beginnings: Historical review of evolutionary

Vries theory of Mutation,

Sympatric, Allopatric and

Process of evolution: Genetic variations in population, Hardy-

Weinberg Equilibrium. Evolutionary forces (Genetic Drift: mechanism,

non; Role of Migration and Mutation in

12 L

Total 60 L

Page 7: School: Science Programme: Bachelor of Science (B.Sc ...

Course Outcome

Students should able to

CO1 Students will understand the Ecosystem, its component and functions.

CO2 Students will understand the

CO3 Students will understand the need and importance of ecological conservation

CO4 Students will understand the Origin and Evolution of Life

Resources

Recommended

Books

1. Colinvaux, P. A. (1993). Ecology. II Edition. Wiley, John and Sons, Inc.

2. Krebs, C. J. (2001). Ecology. VI Edition. Benjamin Cummings.

3. Odum, E.P., (2008). Fundamentals of Ecology. Indian Edition.

Brooks/Cole

4. Robert Leo Smith Ecology and field biology Ha

5. Ricklefs, R.E., (2000). Ecology. V Edition. Chiron Pres

6. Evolution by Strickberger

Reference

Books

1. Colinvaux, P. A. (1993). Ecology. II Edit

2. Krebs, C. J. (2001). Ecology. VI Edition. Benjamin Cummings.

3. Robert Leo Smith Ecology and field biology Harper and Row publisher.

4. Edition Wiley

5. Miller

Students will understand the Ecosystem, its component and functions.

Students will understand the Environmental Pollution and its control measures.

Students will understand the need and importance of ecological conservation

Students will understand the Origin and Evolution of Life

Colinvaux, P. A. (1993). Ecology. II Edition. Wiley, John and Sons, Inc.

Krebs, C. J. (2001). Ecology. VI Edition. Benjamin Cummings.

Odum, E.P., (2008). Fundamentals of Ecology. Indian Edition.

Brooks/Cole.

Robert Leo Smith Ecology and field biology Harper and Row publisher

Ricklefs, R.E., (2000). Ecology. V Edition. Chiron Pres

Evolution by Strickberger

Colinvaux, P. A. (1993). Ecology. II Edition. Wiley, John and Sons, Inc.

Krebs, C. J. (2001). Ecology. VI Edition. Benjamin Cummings.

Robert Leo Smith Ecology and field biology Harper and Row publisher.

Edition Wiley- Blackwell.

Miller - Environmental Biology.

Pa

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Environmental Pollution and its control measures.

Students will understand the need and importance of ecological conservation

Colinvaux, P. A. (1993). Ecology. II Edition. Wiley, John and Sons, Inc.

Krebs, C. J. (2001). Ecology. VI Edition. Benjamin Cummings.

Odum, E.P., (2008). Fundamentals of Ecology. Indian Edition.

rper and Row publisher.

Ricklefs, R.E., (2000). Ecology. V Edition. Chiron Press

ion. Wiley, John and Sons, Inc.

Krebs, C. J. (2001). Ecology. VI Edition. Benjamin Cummings.

Robert Leo Smith Ecology and field biology Harper and Row publisher.

Page 8: School: Science Programme: Bachelor of Science (B.Sc ...

Year: Second Year

Course: Ecology and Evolution

Teaching

Scheme

(Hrs/Week)

Continuous

L T P C CIA-1 CIA

0 0 2 1 - -

Max. Time, End Semester Exam (

Objectives

1 To understand quadrat method for vegetation.

2 To understand the physicochemical parameters of soil.

3 To understand the biological parameters of water.

Sr. No.

1 Determination of requisite size of the quadra

2 Analysis of frequency distribution of plants in a piece of vegetation by quadrat

method

3 Determination of density and abundance of plant species in a piece of

quadrat method.

4 Physicochemical analysis of soil (Colour, Texture, Water Holding capacity, pH)

5 Biological analysis of water sample (DO, BOD, COD, pH)

6 Determination of chlorophyll content in leaf from polluted areas

7 Report on a visit to National Park/Biodiversity Park/Wild life sanctuary

8 Study of fossils from models/ pictures.

Term Work:

Term Work assessment shall be conducted for the Project, Tutorials and Seminar. Term work is

continuous assessment based on

journal/record book, oral/viva, respectively

institute. At the end of the semester, the final grade for a Term Work shall be assigned based on

the performance of the student and is to be submitted to the University.

School of Science

B.Sc. Microbiology

Semester: I

Ecology and Evolution Laboratory Course Code:

Continuous Internal Assessment (CIA) End Semester

Examination

CIA-2 CIA-3 CIA-4 Lab Theory

- - - 25 -

End Semester Exam (Practical) – 2 Hrs.

To understand quadrat method for vegetation.

To understand the physicochemical parameters of soil.

To understand the biological parameters of water.

Description

of requisite size of the quadrat for vegetation analysis

Analysis of frequency distribution of plants in a piece of vegetation by quadrat

Determination of density and abundance of plant species in a piece of

Physicochemical analysis of soil (Colour, Texture, Water Holding capacity, pH)

Biological analysis of water sample (DO, BOD, COD, pH)

Determination of chlorophyll content in leaf from polluted areas

Report on a visit to National Park/Biodiversity Park/Wild life sanctuary

Study of fossils from models/ pictures.

Term Work assessment shall be conducted for the Project, Tutorials and Seminar. Term work is

continuous assessment based on attendance, good laboratory practice (GPL), timely completion,

journal/record book, oral/viva, respectively. It should be assessed by course

institute. At the end of the semester, the final grade for a Term Work shall be assigned based on

the performance of the student and is to be submitted to the University.

Pa

ge1

Semester: IV

Course Code: XLS311

End Semester

Examination Total

Lab

25 50

t for vegetation analysis

Analysis of frequency distribution of plants in a piece of vegetation by quadrat

Determination of density and abundance of plant species in a piece of vegetation by

Physicochemical analysis of soil (Colour, Texture, Water Holding capacity, pH)

Determination of chlorophyll content in leaf from polluted areas

Report on a visit to National Park/Biodiversity Park/Wild life sanctuary

Term Work assessment shall be conducted for the Project, Tutorials and Seminar. Term work is

attendance, good laboratory practice (GPL), timely completion,

course teacher of the

institute. At the end of the semester, the final grade for a Term Work shall be assigned based on

Page 9: School: Science Programme: Bachelor of Science (B.Sc ...

Notes

1 The regular attendance of

monitored and marks will be given accordingly (

2 Good Laboratory Practices (

3 Timely Completion (05 Marks)

4 Journal / Record Book (05

5 Oral / Viva (05 Marks)

Practical/Oral/Presentation:

Practical/Oral/Presentation shall be conducted and assessed jointly by at least a pair of examiners

appointed as internal and external examiners by the University. The examiners will prepare the

mark/grade sheet in the format

envelope shall be submitted to the head of the department or authorized person.

Notes

1 One experiment from the regular practical syllabus will be conducted (

2 Oral/Viva-voce (05 Marks).

The regular attendance of the students during semester for practical course will be

rks will be given accordingly (05 Marks).

Good Laboratory Practices (05 Marks)

Marks)

05 Marks)

Practical/Oral/Presentation:

Practical/Oral/Presentation shall be conducted and assessed jointly by at least a pair of examiners

appointed as internal and external examiners by the University. The examiners will prepare the

mark/grade sheet in the format as specified by the University, authenticate and seal it. Sealed

envelope shall be submitted to the head of the department or authorized person.

One experiment from the regular practical syllabus will be conducted (

Marks).

Pa

ge2

practical course will be

Practical/Oral/Presentation shall be conducted and assessed jointly by at least a pair of examiners

appointed as internal and external examiners by the University. The examiners will prepare the

as specified by the University, authenticate and seal it. Sealed

envelope shall be submitted to the head of the department or authorized person.

One experiment from the regular practical syllabus will be conducted (20 Marks).

Page 10: School: Science Programme: Bachelor of Science (B.Sc ...

Year: Second Year

Course: Medical Microbiology

Teaching

Scheme

(Hrs/Week)

Continuous Internal Assessment (CIA)

L T P C CIA-1 CIA

4 0 - 4 10 20

Max. Time, End Semester Exam (Theory)

Prerequisite Basic awareness of infections

Objectives

1 To impart the knowledge of

2 To familiarize the students

parasites

3 To introduce the concepts

4 To apply the knowledge

5 To understand the opportunities in medical

Unit

Number

1

Introduction to infectious diseases of following human body systems: (Brief

anatomy and physiology, Diseases, Pathogens and Symptoms )

a. Respiratory system

b. Gastrointestinal system

c. Kidney and Liver

d. Genital system

e. Central nervous system

2

Epidemiology: a. Definition, scope and applications b. Incidence and

prevalence rates, mortality and morbidity rates c

on time, place and person d. Case control and cohort studies

and application e. Principle and methods

(Randomized control trials Concurrent parallel and cross

Epidemiology of infectious diseases i. Sources and reservoirs of infection ii.

Modes of transmission of infections iii. Disease prevention and control

measures

3

Study of following groups of bacterial pathogens: (with respect to

Classification and Biochemical characters, Antigenic structure, Viability

characteristics, Pathogenicity, Pathogenesis, Symptoms, Laboratory

diagnosis, Epidemiology, Prophylaxis and Che

i. Enteric pathogens (E. coli, Shigella, Salmonella, Campylobacter,

Vibrio)

ii. Pneumococci and Neiserria

iii. Pyogenic organisms

School of Science

B.Sc. Microbiology

Semester: I

Medical Microbiology Course Code:

Continuous Internal Assessment (CIA) End Semester

Examination

CIA-2 CIA-3 CIA- 4 Lab Theory

20 10 10 - 50

End Semester Exam (Theory) - 3Hrs.

Basic awareness of infections

impart the knowledge of medical microbiology

To familiarize the students variety of infectious agents including bacteria, viruses, fungi and

introduce the concepts virulence and pathogenesis related with infectious agents

pply the knowledge for development of new diagnostic tools and techniques

understand the opportunities in medical research

Details

Introduction to infectious diseases of following human body systems: (Brief

anatomy and physiology, Diseases, Pathogens and Symptoms )

a. Respiratory system

b. Gastrointestinal system

c. Kidney and Liver

e. Central nervous system

Epidemiology: a. Definition, scope and applications b. Incidence and

prevalence rates, mortality and morbidity rates c. Disease distribution based

on time, place and person d. Case control and cohort studies

and application e. Principle and methods – Clinical trials of drugs and vaccines

(Randomized control trials Concurrent parallel and cross-

Epidemiology of infectious diseases i. Sources and reservoirs of infection ii.

Modes of transmission of infections iii. Disease prevention and control

Study of following groups of bacterial pathogens: (with respect to

Classification and Biochemical characters, Antigenic structure, Viability

characteristics, Pathogenicity, Pathogenesis, Symptoms, Laboratory

diagnosis, Epidemiology, Prophylaxis and Chemotherapy):

Enteric pathogens (E. coli, Shigella, Salmonella, Campylobacter,

Vibrio)

Pneumococci and Neiserria

Pyogenic organisms – Staphylococcus, Streptococcus,

Pa

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Semester: IV

Course Code: XMI401

Semester

Examination Total

Lab

- 100

including bacteria, viruses, fungi and

virulence and pathogenesis related with infectious agents

development of new diagnostic tools and techniques

Hours

Introduction to infectious diseases of following human body systems: (Brief

anatomy and physiology, Diseases, Pathogens and Symptoms ) 12 L

Epidemiology: a. Definition, scope and applications b. Incidence and

. Disease distribution based

on time, place and person d. Case control and cohort studies – study design

Clinical trials of drugs and vaccines

-over trials) f.

Epidemiology of infectious diseases i. Sources and reservoirs of infection ii.

Modes of transmission of infections iii. Disease prevention and control

12 L

Study of following groups of bacterial pathogens: (with respect to -

Classification and Biochemical characters, Antigenic structure, Viability

characteristics, Pathogenicity, Pathogenesis, Symptoms, Laboratory

Enteric pathogens (E. coli, Shigella, Salmonella, Campylobacter,

Staphylococcus, Streptococcus,

12 L

Page 11: School: Science Programme: Bachelor of Science (B.Sc ...

Pseudomonas

iv. Spirochetes

v. Clostridium tetani and Clostridium perfr

vi. Bacillus anthracis

vii. Acinetobacter spp.

viii. Mycobacterium tuberculosis and Mycobacterium leprae

ix. Rickettsia

4

Chemotherapy: 1. Introduction to chemotherapy 2. Desirable parameters of

chemotherapeutic agent (Selective toxicity, Bioavailability of Drug, MIC,

MBC, LD-50 value, routes of drug administration) 3. Mode of action of

antimicrobial agents on:

a. Bacteria: i. Cell wall (Beta lactams [1st to 6th Generation

Imipenem Piperacillin], Tazobactam, Cycloserine, Bacitracin) ii. Cell

membrane (Polymyxin, Monensin) iii. Protein synthesis (Streptomycin,

Tetracycline) iv. Nucleic acids (Na

Enzyme inhibitors (Trimethoprim)

b. Fungi: (Griseofulvin, Nystatin, Amphotericin B, Anidulafungin,

Voriconazole)

c. Viruses: (Acyclovir, Zidovudine, Oseltamivir)

d. Protozoa: (Metronidazole, Mepacrine)

Antibiotic resistance:

5

a. Cultivation of viruses

b. Study of following groups of viral pathogens (with respect to

characteristics, Viability characteristics, Pathogenicity

Symptoms, Laboratory diagnosis including serological diagnosis,

Epidemiology, Prophylaxis and Chemotherapy): i. HIV ii. Polio virus iii.

Hemorrhagic viruses (Dengue, Ebola) iv. Hepatitis A and Hepatitis B viruses

v. Influenza virus (human,

vii. Japanese encephalitis virus viii. Rota virus ix. Rhabdoviruses (Rabies) x.

Herpes Virus (simplex, zoster) xi. Oncogenic viruses (DNA, RNA)

c. Other pathogens

and non candida fungal pathogens

Course Outcome

Students should able to

CO1 Student will be able to

CO2 Student will be able to

CO3 Student will be able to

CO4 Student will be able to

CO5 Student will be able to

Pseudomonas

Spirochetes – Treponema, Leptospira

Clostridium tetani and Clostridium perfringens

Bacillus anthracis

Acinetobacter spp.

Mycobacterium tuberculosis and Mycobacterium leprae

Rickettsia

Chemotherapy: 1. Introduction to chemotherapy 2. Desirable parameters of

chemotherapeutic agent (Selective toxicity, Bioavailability of Drug, MIC,

50 value, routes of drug administration) 3. Mode of action of

antimicrobial agents on:

a. Bacteria: i. Cell wall (Beta lactams [1st to 6th Generation- e.g. Meropenem,

Imipenem Piperacillin], Tazobactam, Cycloserine, Bacitracin) ii. Cell

membrane (Polymyxin, Monensin) iii. Protein synthesis (Streptomycin,

Tetracycline) iv. Nucleic acids (Nalidixic acid, Rifamycin, Quinolones) v.

Enzyme inhibitors (Trimethoprim)

b. Fungi: (Griseofulvin, Nystatin, Amphotericin B, Anidulafungin,

c. Viruses: (Acyclovir, Zidovudine, Oseltamivir)

d. Protozoa: (Metronidazole, Mepacrine)

c resistance: Development and mechanism of antibiotic resistance

Cultivation of viruses

b. Study of following groups of viral pathogens (with respect to

characteristics, Viability characteristics, Pathogenicity, Pathogenesis,

Symptoms, Laboratory diagnosis including serological diagnosis,

Epidemiology, Prophylaxis and Chemotherapy): i. HIV ii. Polio virus iii.

Hemorrhagic viruses (Dengue, Ebola) iv. Hepatitis A and Hepatitis B viruses

v. Influenza virus (human, swine and bird) vi. FMD virus and Rinderpest virus

vii. Japanese encephalitis virus viii. Rota virus ix. Rhabdoviruses (Rabies) x.

Herpes Virus (simplex, zoster) xi. Oncogenic viruses (DNA, RNA)

ther pathogens - such as Plasmodium, Entamoeba and Giardia, Candida

and non candida fungal pathogens

Student will be able to describe various pathogens responsible for infections

Student will be able to explain mechanism of pathogenesis

Student will be able to understand the importance of infectious agents and their detection

Student will be able to apply the knowledge in diagnostics

Student will be able to understand principles and opportunities in medical

Pa

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Mycobacterium tuberculosis and Mycobacterium leprae

Chemotherapy: 1. Introduction to chemotherapy 2. Desirable parameters of

chemotherapeutic agent (Selective toxicity, Bioavailability of Drug, MIC,

50 value, routes of drug administration) 3. Mode of action of

e.g. Meropenem,

Imipenem Piperacillin], Tazobactam, Cycloserine, Bacitracin) ii. Cell

membrane (Polymyxin, Monensin) iii. Protein synthesis (Streptomycin,

lidixic acid, Rifamycin, Quinolones) v.

b. Fungi: (Griseofulvin, Nystatin, Amphotericin B, Anidulafungin,

of antibiotic resistance

12 L

b. Study of following groups of viral pathogens (with respect to – Virion

, Pathogenesis,

Symptoms, Laboratory diagnosis including serological diagnosis,

Epidemiology, Prophylaxis and Chemotherapy): i. HIV ii. Polio virus iii.

Hemorrhagic viruses (Dengue, Ebola) iv. Hepatitis A and Hepatitis B viruses

swine and bird) vi. FMD virus and Rinderpest virus

vii. Japanese encephalitis virus viii. Rota virus ix. Rhabdoviruses (Rabies) x.

Herpes Virus (simplex, zoster) xi. Oncogenic viruses (DNA, RNA)

Giardia, Candida

12 L

Total 60

various pathogens responsible for infections

importance of infectious agents and their detection

opportunities in medical microbiology

Page 12: School: Science Programme: Bachelor of Science (B.Sc ...

Resources

Recommended

Books

1. Tortora, G.J., Funke, B.R., Case, C.L, 1992. Microbiology: An introduction

5th Edition, Benjamin Pub. Co. NY

2. Chakraborty, P., 2003 A textbook of Microbiology, 2nd Edition New Central

Book Agency, India.

3. Davis B.D., Delbacco, 1990 Microbiology 4th edition, J.B. Lippincott Co. NY

4. Wolfgang K. Joklik, 1992, Zinsser Microbiology 20th Edition, McGraw

Professional Publishing.

5. Dey, N.C and Dey, TK. 1988, Medical Bacteriology, Allied Agency, Calcutt

17th Edition

6. Ananthnarayana, R. and C.E, Jayaram Panikar, 1996 Text book of

microbiology, 5th edition, Orient Longman.

7. Park and Park, Preventive and Social medicine. 2013, Publisher: Banarsidas

Bhanot, Jabalpur

8. David Greenwood, 1995, Antim

University Press.

9. Franklin, T.J and Snow, G. A. 2012, Biochemistry of Antimicrobial Action.

Springer Science & Business Media

10. Mukherjee, K.L 1988 Medical Laboratory Technology, Vol III, 10th Edition,

Tata Mc. Graw

Reference

Books

1. Roitt, P.I: Mims, C.J. Medical Microbiology

2. Medical Microbiology edited by Samuel Baron. Fourth edition. (University

of Texas Medical Branch of Galvesion)

3. Sherris, John C, Ed, Medical Microbiology: an Introduction to infectious

diseases. Elsevier Publication IInd edition.

4. Virulence mechanisms of b

Bolin, Brogden Minion and Michael.

5. Ganti, A. Sastry.1975. Veterinary Pathology. Seventh Edition. Revised by P.

Rama Rao.

1. Tortora, G.J., Funke, B.R., Case, C.L, 1992. Microbiology: An introduction

5th Edition, Benjamin Pub. Co. NY

. Chakraborty, P., 2003 A textbook of Microbiology, 2nd Edition New Central

Book Agency, India.

Davis B.D., Delbacco, 1990 Microbiology 4th edition, J.B. Lippincott Co. NY

. Wolfgang K. Joklik, 1992, Zinsser Microbiology 20th Edition, McGraw

Professional Publishing.

. Dey, N.C and Dey, TK. 1988, Medical Bacteriology, Allied Agency, Calcutt

17th Edition

. Ananthnarayana, R. and C.E, Jayaram Panikar, 1996 Text book of

microbiology, 5th edition, Orient Longman.

. Park and Park, Preventive and Social medicine. 2013, Publisher: Banarsidas

Bhanot, Jabalpur

. David Greenwood, 1995, Antimicrobial Chemotherapy, 3rd Edition, Oxford

University Press.

. Franklin, T.J and Snow, G. A. 2012, Biochemistry of Antimicrobial Action.

Springer Science & Business Media

. Mukherjee, K.L 1988 Medical Laboratory Technology, Vol III, 10th Edition,

Tata Mc. Graw-Hill Pub Co

Roitt, P.I: Mims, C.J. Medical Microbiology

Medical Microbiology edited by Samuel Baron. Fourth edition. (University

of Texas Medical Branch of Galvesion)

Sherris, John C, Ed, Medical Microbiology: an Introduction to infectious

diseases. Elsevier Publication IInd edition.

Virulence mechanisms of bacterial pathogens (Second edition) by Roth,

Bolin, Brogden Minion and Michael.

Ganti, A. Sastry.1975. Veterinary Pathology. Seventh Edition. Revised by P.

Rama Rao.

Pa

ge3

1. Tortora, G.J., Funke, B.R., Case, C.L, 1992. Microbiology: An introduction

. Chakraborty, P., 2003 A textbook of Microbiology, 2nd Edition New Central

Davis B.D., Delbacco, 1990 Microbiology 4th edition, J.B. Lippincott Co. NY

. Wolfgang K. Joklik, 1992, Zinsser Microbiology 20th Edition, McGraw-Hill

. Dey, N.C and Dey, TK. 1988, Medical Bacteriology, Allied Agency, Calcutta,

. Ananthnarayana, R. and C.E, Jayaram Panikar, 1996 Text book of

. Park and Park, Preventive and Social medicine. 2013, Publisher: Banarsidas

icrobial Chemotherapy, 3rd Edition, Oxford

. Franklin, T.J and Snow, G. A. 2012, Biochemistry of Antimicrobial Action.

. Mukherjee, K.L 1988 Medical Laboratory Technology, Vol III, 10th Edition,

Medical Microbiology edited by Samuel Baron. Fourth edition. (University

Sherris, John C, Ed, Medical Microbiology: an Introduction to infectious

acterial pathogens (Second edition) by Roth,

Ganti, A. Sastry.1975. Veterinary Pathology. Seventh Edition. Revised by P.

Page 13: School: Science Programme: Bachelor of Science (B.Sc ...

Year: Second Year

Course: Medical Microbiology

Teaching

Scheme

(Hrs/Week)

Continuous Internal Assessment (CIA)

L T P C CIA-1 CIA

0 0 4 2 -

Max. Time, End Semester Exam (Theory)

Objectives

1 Student will understand handling

2 Student will understand the process for determination of antibiotic profile of bacterial

pathogens.

3 Student will acquire knowledge

Sr.

No.

1 Clinical microbiology:

a. Physical, Chemical and Microscopic examination of Clinical samples

pus, sputum

b. Isolation, identification of following pathogens from clinical samples: E. coli,

Salmonella spp., Pseudomonas spp., Proteus spp., Klebsiella spp., Shigella spp.,

Staphylococcus spp, Streptococcus spp. (for identification use of keys as well as Bergey’

Manual is recommended) 2 Study of growth characters of isolated pathogens on following media: Mannitol Salt Agar,

Wilson Blair agar, Salmonella Shigella agar, Glucose azide medium, Cetrimide agar, TSI

agar

3 Antibiotic sensitivity testing of the isolates (for Gram negative and Gram Positive)

4 Demonstration of permanent slides of following parasites:

a. Entamoeba histolytica

b. Ascaris spp.

c. Plasmodium spp. d. Mycobacterium( tuberculosis and leprae)5 Epidemiological survey: Development of hypothesis, Data collection, organization,

statistical analysis, graphical representation using computers and interpretation,

Preparation of report 6 Germ tube test for detection of Candida spp.

7 Slide culture method and staining of fungal strains

8 Acid fast staining

9 Visit to hospital or pathology lab

School of Science

B.Sc Microbiology

Semester: I

Medical Microbiology Laboratory Course Code:

Continuous Internal Assessment (CIA) End Semester

Examination

CIA-2 CIA-3 CIA- 4 Lab Theory

- - - 50 -

End Semester Exam (Theory) - 2Hrs.

handling of various pathogenic microorganisms.

understand the process for determination of antibiotic profile of bacterial

acquire knowledge of the microbiological examination in clinical set up.

Description

Clinical microbiology:

a. Physical, Chemical and Microscopic examination of Clinical samples

b. Isolation, identification of following pathogens from clinical samples: E. coli,

Salmonella spp., Pseudomonas spp., Proteus spp., Klebsiella spp., Shigella spp.,

Staphylococcus spp, Streptococcus spp. (for identification use of keys as well as Bergey’

Manual is recommended)

Study of growth characters of isolated pathogens on following media: Mannitol Salt Agar,

Wilson Blair agar, Salmonella Shigella agar, Glucose azide medium, Cetrimide agar, TSI

Antibiotic sensitivity testing of the isolates (for Gram negative and Gram Positive)

Demonstration of permanent slides of following parasites:

a. Entamoeba histolytica

c. Plasmodium spp. d. Mycobacterium( tuberculosis and leprae)

Epidemiological survey: Development of hypothesis, Data collection, organization,

statistical analysis, graphical representation using computers and interpretation,

Germ tube test for detection of Candida spp.

method and staining of fungal strains

Visit to hospital or pathology lab

Pa

ge1

Semester: IV

Course Code: XMI411

End Semester

Examination Total

Lab

50 100

various pathogenic microorganisms.

understand the process for determination of antibiotic profile of bacterial

microbiological examination in clinical set up.

a. Physical, Chemical and Microscopic examination of Clinical samples – urine, stool,

b. Isolation, identification of following pathogens from clinical samples: E. coli,

Salmonella spp., Pseudomonas spp., Proteus spp., Klebsiella spp., Shigella spp.,

Staphylococcus spp, Streptococcus spp. (for identification use of keys as well as Bergey’s

Study of growth characters of isolated pathogens on following media: Mannitol Salt Agar,

Wilson Blair agar, Salmonella Shigella agar, Glucose azide medium, Cetrimide agar, TSI

Antibiotic sensitivity testing of the isolates (for Gram negative and Gram Positive)

Epidemiological survey: Development of hypothesis, Data collection, organization,

statistical analysis, graphical representation using computers and interpretation,

Page 14: School: Science Programme: Bachelor of Science (B.Sc ...

Term Work:

Term Work assessment shall be conducted for the Project, Tutorials and Seminar. Term work is

continuous assessment based on

journal/record book, oral/viva, respectively

the end of the semester, the final grade for a Term Work shall be assigned based on the performance of

the student and is to be submitted to the University.

Notes

1 The regular attendance of

marks will be given accordingly (10

2 Good Laboratory Practices (

3 Timely Completion (10 Marks)

4 Journal / Record Book (10 Marks)

5 Oral / Viva (10 Marks)

Practical/Oral/Presentation:

Practical/Oral/Presentation shall be conducted and assessed jointly by at least a pair of examiners

appointed as internal and external

mark/grade sheet in the format as specified by the University, authenticate and seal it. Sealed envelope

shall be submitted to the head of the department or authorized person

Notes

1 One experiment from the regular practical syllabus will be conducted (40 Marks).

2 Oral/Viva-voce (10 Marks).

Term Work assessment shall be conducted for the Project, Tutorials and Seminar. Term work is

continuous assessment based on attendance, good laboratory practice (GPL), timely completion,

journal/record book, oral/viva, respectively. It should be assessed by course

the end of the semester, the final grade for a Term Work shall be assigned based on the performance of

the student and is to be submitted to the University.

The regular attendance of the students during semester for practical course will be monitored and

rks will be given accordingly (10 Marks).

Good Laboratory Practices (10 Marks)

Timely Completion (10 Marks)

Journal / Record Book (10 Marks)

Practical/Oral/Presentation:

Practical/Oral/Presentation shall be conducted and assessed jointly by at least a pair of examiners

internal and external examiners by the University. The examiners will prepare the

mark/grade sheet in the format as specified by the University, authenticate and seal it. Sealed envelope

shall be submitted to the head of the department or authorized person.

One experiment from the regular practical syllabus will be conducted (40 Marks).

voce (10 Marks).

Pa

ge2

Term Work assessment shall be conducted for the Project, Tutorials and Seminar. Term work is

laboratory practice (GPL), timely completion,

course teacher of the institute. At

the end of the semester, the final grade for a Term Work shall be assigned based on the performance of

practical course will be monitored and

Practical/Oral/Presentation shall be conducted and assessed jointly by at least a pair of examiners

The examiners will prepare the

mark/grade sheet in the format as specified by the University, authenticate and seal it. Sealed envelope

One experiment from the regular practical syllabus will be conducted (40 Marks).


Recommended