Carla LORETOAssociate Professor
Paola CASTROGIOVANNIAssistant Professor
Rosa IMBESIAssistant Professor
Giuseppe MUSUMECIAssociate Professor
Salvatore GIUNTA Assistant Professor
Marta Anna SZYCHLISKAAssistant Professor
Michelino DI ROSAAssistant Professor
Velia D’AGATAFull ProfessorSection Coordinator
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Faculty members
Biometec: a research for life
Section of Human Anatomy and Histology
Laboratory of Neurobiology- Molecular mechanisms involved in neurodegenerative disease such as Parkinson disease and Amyotrophic Lateral Sclerosis
- Pathophysiological role of VIP family members in the brain
- Molecular mechanisms involved in retinal degeneration during diabetic retinopathy development
Laboratory of Functional Organ Anatomy- Asbestos exposure correlated organ-diseases.
- Temporomandibular joint (TMJ) disorders.
- Biomolecular mechanisms alterations in Peyronie’s disease (PD).
- Surgical anatomy of male urethra.
Laboratory of Tissue Engineering- Osteoarthritis and musculoskeletal conditions and the relative effects of diet, ageing and physical activity
- Tissue engineering for tissue regeneration using
mesenchymal stem cells and mechanobiology
22 Biometec: a research for life
Section of Human Anatomy and Histology
Laboratory of Molecular Histology and Cellular Morphology- Immune cellular differentiation
- Molecular pathways regulation during monocyte differentiation
23Biometec: a research for life
Section of Human Anatomy and Histology
Farmakológiai és Farmakoterápiás IntézetSemmelweis Egyetem, Általános Orvostudományi Kar
24 Biometec: a research for life
INTERNATIONAL COLLABORATIONS
Section of Human Anatomy and Histology
2013-2016 Swiss National Science Foundation:SNF-31003A_146375/1
2015 AGRO-TRA Project(PO FESR Sicilia 2007/2013)
GRANTS
2012-2015 HIPPOCRATES - PON02_00355Distretto Tecnologico Sicilia Micro
e Nano Sistemi S.c.a.r.l
25Biometec: a research for life
Section of Human Anatomy and Histology
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Research paper selection of Biometec (2014-2018)Physical activity ameliorates cartilage degeneration in a rat model of aging: a study on lubricin expression.Musumeci G, Castrogiovanni P, Trovato FM, Imbesi R, Giunta S, Szychlinska MA, Loreto C, Castorina S, Mobasheri A. Scand J Med Sci Sports. 2015 Apr;25(2):e222-30.
Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet.Musumeci G, Castrogiovanni P, Castorina S, Imbesi R, Szychlinska MA, Scuderi S, Loreto C, Giunta S. Brain Res Bull. 2015 Oct;119(Pt A):12-8.
Expression profile of Wilms Tumor 1 (WT1) isoforms in undifferentiated and all-trans retinoic acid differentiated neuroblastoma cells.Maugeri G, D’Amico AG, Rasà DM, Reitano R, Saccone S, Federico C, Parenti R, Magro G, D’Agata V. Genes Cancer. 2016 Jan;7(1-2):47-58.
Co-Expression and Co-Localization of Cartilage Glycoproteins CHI3L1 and Lubricin in Osteoarthritic Cartilage: Morphological, Immunohistochemical and Gene Expression Profiles.Szychlinska MA, Trovato FM, Di Rosa M, Malaguarnera L, Puzzo L, Leonardi R, Castrogiovanni P, Musumeci G. Int J Mol Sci. 2016 Mar 11;17(3):359.
ADAM10 localization in temporomandibular joint disk with internal derangement: an ex vivo immunohistochemical study.Loreto C, Chiarenza GP, Musumeci G, Castrogiovanni P, Imbesi R, Ruggeri A, Almeida LE, Leonardi R. Acta Histochem. 2016 Apr;118(3):293-8.
Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis.Musumeci G, Castrogiovanni P, Szychlinska MA, Imbesi R, Loreto C, Castorina S, Giunta S. Brain Res Bull.2017 Jan;128:76-82.
VIP Family Members Prevent Outer Blood Retinal Barrier Damage in a Model of Diabetic Macular Edema.Maugeri G, D’Amico AG, Gagliano C, Saccone S, Federico C, Cavallaro S, D’Agata V. J Cell Physiol. 2017 May;232(5):1079-1085.
Occupational exposure to Mount Etna’s basaltic dust: Assessment of mutagenic and cytotoxic effects.Ledda C, Cocuzza S, Salerno M, Senia P, Matera S, Rapisarda V, Loreto C. Mol Med Rep. 2017 May;15(5):3350-3354.
Engineered cartilage regeneration from adipose tissue derived-mesenchymal stem cells: A morphomolecular study on osteoblast, chondrocyte and apoptosis evaluation.Szychlinska MA, Castrogiovanni P, Nsir H, Di Rosa M, Guglielmino C, Parenti R, Calabrese G, Pricoco E, Salvatorelli L, Magro G, Imbesi R, Mobasheri A, Musumeci G. Exp Cell Res. 2017 Aug 15;357(2):222-235.
Trophic effect of PACAP on human corneal endothelium.Maugeri G, Longo A, D’Amico AG, Rasà DM, Reibaldi M, Russo A, Bonfiglio V, Avitabile T, D’Agata V. Peptides. 2018 Jan;99:20-26. doi: 10.1016/j.peptides.2017.11.003.
Physical activity and Mediterranean diet based on olive tree phenolic compounds from two different geographical areas have protective effects on early osteoarthritis, muscle atrophy and hepatic steatosis.Szychlinska MA, Castrogiovanni P, Trovato FM, Nsir H, Zarrouk M, Lo Furno D, Di Rosa M, Imbesi R, Musumeci G. Eur J Nutr. 2018 Feb 15.
Impact of Western and Mediterranean Diets and Vitamin D on Muscle Fibers of Sedentary Rats.Trovato FM, Castrogiovanni P, Szychlinska MA, Purrello F, Musumeci G. Nutrients. 2018 Feb 17;10(2).
PACAP and VIP regulate hypoxia-inducible factors in neuroblastoma cells exposed to hypoxia.Maugeri G, D’Amico AG, Rasà DM, Saccone S, Federico C, Cavallaro S, D’Agata V. Neuropeptides. 2018 Jun; 69:84-91. doi: 10.1016/j.npep.2018.04.009. Epub 2018 Apr 17.
Molecular mechanisms involved in the protective effect of pituitary adenylate cyclase-activating polypeptide in an in vitro model of amyotrophic lateral sclerosis.Maugeri G, D’Amico AG, Rasà DM, Federico C, Saccone S, Morello G, La Cognata V, Cavallaro S, D’Agata V. J Cell Physiol. 2018 Sep 21. doi:10.1002/jcp.27328.
Expression of the OAS Gene Family Is Highly Modulated in Subjects Affected by Juvenile Dermatomyositis, Resembling an Immune Response to a dsRNA Virus Infection.Musumeci G, Castrogiovanni P, Barbagallo I, Tibullo D, Sanfilippo C, Nunnari G, Pellicanò GF, Pavone P, Caltabiano R, Di Marco R, Imbesi R, Di Rosa M. Int J Mol Sci. 2018 Sep 17;19(9).
PACAP through EGFR transactivation preserves human corneal endothelial integrity.Maugeri G, D’Amico AG, Castrogiovanni P, Saccone S, Federico C, Reibaldi M, Russo A, Bonfiglio V, Avitabile T, Longo A, D’Agata V. J Cell Biochem. 2018 Dec 11. doi: 10.1002/jcb.28293
Biometec: a research for life
Section of Human Anatomy and Histology
