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Präsentation Z-Systems®

für das Brassler Management

14.08.2013

A highly relevant innovation for the premium dental implant market

Z-Systems is:

• 100% Swiss Company with 15 years of ceramic research experience:

• Nearly 10 years of clinical experience (since 2004) ~ 25‘000 ceramic implants placed worldwide• Z-Systems is a safe, highly biocompatible and esthetic alternative to titanium implants.

• All products are FDA, CE, ISO 9001, ISO 13485 certified and produced according to the «Medical Device Directive» MDD 93/42/EEC. We are the only zirkonia – implant company with annual CE inspection and successfully passed FDA-Inspektions.

• A unique process of development, material treatment, quality assurance and production and finishing that is leads to our «Zirkolith®» implants.

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Z-Systems® looks back to a unique experience and continous progress of ceramic dental implants.

Z1 1. Generation

2001

Z22. Generation

Z-Lock 3-XXX3. Generation

2004 CE + FDA

Z-Look 3 EVO4. Generation

2009 CE + FDA

Z-Look 3 EVO rapide5. Generation with laser surface+20% stability vs. 3. Gen.>99% Implant survival (1Yr., >3000 cases)2011 CE, FDA Dec 2012

>99% Implantat survival rate

>3000 implants placed

Though circonia was the material of choice at the very beginning of dental implantology, extensive research, development and innovation of production technology was required to meet the high standards of longlasting esthetics and reliability which clinicians and patients rightly demand from a leading implant system.

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Key Learnings

1. Ceramics Implants are different than Titanium ones

a. Circonia Design must be different to titanium. -> Different Geometries are required.

b. Circonia Surfaces should not be acid etched, but Laser Modfied-> This can weaken the implant material and lead to breakages

c. «Ceramic on Ceramic» Connections of implant / abutment must be specifically designed for the specific material properties.

a. Careful evalutation of results is necessary; a long learning curve helpsa. Z-Systems has more than 25 000 Implants placed

b. The latest generation Evo Rapide (Z5m) has been placed more than 3000 cases, with a CSR (=compound survival rate of > 98%)

c. The only ceramic implant with FDA and CE approval

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Since 2004, significant progress has been made – Zirkolith® Implants are on the same level of reliablity as leading premium implants

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Z3 (2004+) Z3 Evo TI Leader N TI Leader i Ti Leader A Ti Leader S Z- Evo Rapid Z- Evo Rapid>1d

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91.1%

CSR (Compound Implant Survival Rate)

99.23%

Sources: Published company Data, Z Quality System / Complaint Data* Wennerberg, Ann: On Macro-, Micro-, and Nanoscopic aspects of Osseointegration (2013)

CSR* N, i, A,S

CSR CSR

Why circonia?

Circonia is highly biocompatible.Compared to titanium it is naturally white, harder, immunologically (LLT- test) preferrable. There is also a reduced level of plaque (biofilm) building and therefore it limits the related risks of peri-implantitis, cardio- vascular deseases and strokes.

Zirkonia … 1. … was the first material that was researched for dental implants. 2. … is used successfully since decades

in different fields of medical surgeries (hip replacements) 3. … has an excellent osseointegration, is immunologically inert

and scientifically well documented. 4. … is the tooth replacement that is optically closer to a natural tooth 5. … is galvanically inactive

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The big questions of zirkonia

For the use in dental implants, the following questions had to be resolved1. Successful Osseointegration

2. Breakage stability

3. Prosthetic Treatment

Z-Systems systematically addressed these questions in the last 10 years. The results for Z-Systems Zirkolith® dental implants are excellent:

1. Osseointegration with CSR (compound implant survival rate) of >99%, at least on par with the leading Ti dental implants.

2. Excellent mechanical properties, making it safe and facilitating early loading- Safe comfort zone in the breakage stability

(>500 N) even after 2 Mio cycles (angulated, in saline - wet environment)significantly higher than max chew strength (~290N)

- can nserted with very high torque values of up to 70 N for high primary stability

3. The Zirkolith® Implantats are prothetically close to a natural tooth: - Can be prepped and grinded directly after the implantation, up to 20 degrees of angle.- With the high possible torque. they can be often immediately restored- The prosthetic process then follows the protocols known from natural teeth

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Material properties of selected ceramics

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raw material

isostatic Pressing

green state processing

sintering

HIP- density increase

hardening and refinement

CAD/ CAM of the implant

Sterilization

SLM (Pat.)

pack and ship

The Zirkolith ® production process

Zirkonoxide - powder formula

Pressing process: temperature, pressure

material integrity processing

Sinterprocess: temperature, pressure

HIPping process

temperature curves and material stiffeness

design of the implant

plasma sterilisation

the patented SLM process

CE certified, FDA approved

production steps Komplexitäts Treiber

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Why Z-Systems® ?

Metallfree, highly biokompatible zirkonia implant hypoallergenic, immunologically more neutral than Ti Less biofilm than Ti implants, reduced risk of peri-implantitis, cardio-

vascular deseases and strokes. highly esthetic, white. Even if there was recession, no grey traces excellent osseointegration – unique laser modified surface ( SLM)

Prosthetically closer to a natural tooth high Torque values of up to 70 for great primary stabilitiy the monotype implant does not need a seperate abutment

– all-in-one – not micro-gap the implant can be prepped and grinded directly after placement and

then be restored like a natural tooth. Unparalleled experience with zirkonia implants

Over 10 years of experience, 10. year clinical data ~25’000 implants placed The reliability of Evo SLM Zirkolith® is on par with the leading Ti

implants

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At the same level of reliabilty, patients prefer white implants

Z – Systems®Zirkolith® Implant

Conventianla Titanium Implant

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Zirkonia for long lasting esthetics

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Z-Systems® 2-teiliges Implantat

• 2005 erste Prototypen gesetzt• Mehrere interne Prototypen über die Jahre entwickelt• 11.11.11 erster finaler Prototyp gesetzt• Bis heute 5 Anwender in mehreren Länder keine Komplikationen (auch

Knochenklasse D4)zeichnen sich aus durch:

• Bewährtes Implantat Design und SLM Oberfläche• Sehr hohes Bruchverhalten, genau wie beim einteiligen Implantat• Eindrehgeometrie erlaubt sehr hohe Eindrehwerte• Einfaches Handling bei der Insertion und proth. Versorgung

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Bilder von Dr. Takahashi

Komplexe Fälle werden wie bei einer zahnbasierten Versorgung behandelt

Planung Punching

3D Guide Drilling Placing

Flapless

After Placement Prepping After Osseointegration Seite 15

A complete, compact solution

A monotype for direct prepping, just like a natural tooth.

A full range of restorative solutions, for single teeth and complex C&B

Novaloc Z-LC and Lockball Z-LB Implantate The new products are based on the existing

designs and restored with the existing Instruments. Only a minimum of additional parts.

A compact, clearly structured surgical kit - for a time and cost effective cleaning and sterilisation.

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1041 – the future of implantology

Innovative new, patented process Successfully used in OMF For immedeate primary stability

After drilling, the implant is pressfitted into the extraction site.

Ultrasonic energy infuses thermoplastic polymers through the implant into the bone.

When the Ultrasonics stop, the implant is anchored reliably into the extraction site.

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Anatomic, non-rotationally symetric implants

Immedeate final loading