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BIOE221
Session 7
The Clinical Approach
Bioscience Department
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The Clinical ApproachSession objectives
• Understand common symptomatology and
how to assess them.
• Demonstrate use of the Clinical
Management Pentagon to plan and
approach clinical cases.
• Identify appropriate physical examinations
to assess signs, symptoms and refine the
differential diagnosis.
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Common Symptomatology
Common symptoms are non-specific to a
particular disease, and are often associated
with a wide variety of conditions affecting
different systems.
Common symptoms must be thoroughly
assessed to facilitate development and
refinement of the differential diagnosis.
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Common Symptomatology
• Pain
• Headache
• Nausea & Vomiting
• Cough
• Breathlessness
• Diarrhoea
• Constipation
• Weight change
• Fatigue & Lethargy
• Fever
• Skin rashes
• Chest pain
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Considerations when assessing
common symptomatology• Location: Where is it occurring?
• Onset: When did it start?
• Duration: How long has it been occurring?
• Severity: How bad is it?
• Causation: What makes it worse/better?
• Pain: Assess using PQRST
• Patient history & current presentation
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Differential Diagnosis
Distinguishing between 2 or more conditions
with similar symptoms by systematically
comparing the signs and symptoms.
Through physical examination you begin to
refine the differential to arrive at the most
likely diagnosis, or, refer the patient for
further testing.
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Acute or Chronic• When determining if a patients presentation
is acute or chronic, you must consider the
presenting symptoms, not just the time
factor.
Example: If a patient has a chronic history of
asthma, but presents with recent onset of
increased episodes of breathlessness and
wheezing, this would be an acute change.
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Acute or Chronic – 4 Ways
Acute Chronic
Acute Acute/AcuteA true acute presentation
e.g. cold or flu
Acute/ChronicAn acute condition
progressing towards chronicity
e.g. Viral infection > CFS
Chronic Chronic/AcuteA chronic condition with an
acute exacerbatione.g. RA flare up
Chronic/ChronicA true chronic presentation
e.g. Dysmenorrhea R/tendometriosis
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Clinical Management Pentagon
(Thakkar, 2017)
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Using the Clinical Management
Pentagon in Clinical Examination
• Observe & Ask: Case history & presentation
• Find & Generate: What systems are affected?
Is it acute or chronic? Define symptom profile.
• Analyse & Interpret: Develop differential
diagnosis
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Using the Clinical Management
Pentagon in Clinical Examination
• Investigate & Reflect: Select physical examinations &
consider expected findings
• Synthesize & Apply: What have the findings shown?
Refine differential diagnosis to decide on the most likely
diagnosis.
• Organize, Manage & Communicate: Develop ongoing
approach, Treat or refer?, Communicate to client and
other health professionals.
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Activity 1 (15 minutes)Consider the following
case presentation:
• 8 year old girl
• Recent cold infection for 1
week
• Minor residual cough: non-
productive
• Feeling of pressure and loss of
hearing in right ear
• Some moderate pain (4/10)
• Temperature = 38.2oC
• History of recurrent upper
respiratory tract infections
Then answer these
questions:
• Is it acute or chronic?
• What systems have been
affected?
• What is the differential
diagnosis?
• What physical examinations
would you need to perform?
• What do you expect to find
from these exams?
• What would be the most likely
diagnosis?
• Treat or refer?
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Case Study
History & Presentation
52 yr old man presents with
persistent dry cough for the last 3
months following a chest infection
resulting in pneumonia for which
he was prescribed antibiotics. He
appears to be overweight, and
has audible breath sounds on
light exertion. He has a history of
tonsillitis as a child, as well as
mild asthma persisting into
adulthood, which has eased since
he quit smoking 5 years ago.
Examination Results
Vital Signs:
• Temp = 37.2oC
• Pulse = 92 reg & weak
• Resp = 18br/min with effort
• BP = 155/85
Appearance:
Pale and tired. Dark circles under
eyes. Stiff in body movements.
Appears a little unkept.
Anthropometrics:
BMI = 30.5kg/m2
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Case Study Instructions
Use the pentagon and
work in small groups to
analyse the case study
and plan your clinical
examination approach.
(20 minutes)
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ReferencesThakkar, M. (2017). Handout clinical management pentagon [class
handout]. Department of Biosciences, Endeavour College of Natural Health, Australia. Retrieved from https://source.endeavourlearninggroup.com.au/coursematerial/pdf/Documents/BIOS222__SN01_Handout-ClinicalManagementPentagon.pdf
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