Slide 1

September 14, 2010

Pierce Hall

McLean HospitalResearch Town

Meeting

Slide 2

1. General Announcements

2. Announcement: New Division

3. Portfolio Management

4. Grant Administration Competencies

5. Q&A / Open Forum

6. Cataldo Mentoring Award Presentation

7. Reception

McLean Research: Town Meeting Agenda

Slide 3

1. Effort Reporting

2. InSight - New Fund Balance Statements

3. Faculty / Post-doc Review Templates

4. McLean Research Intranet Added Feature:• “Feedback / How Can We Help?”

5. McLean Research Day • Thursday, January 13th, 2011, 1:00 - 5:30 p.m.

McLean Research: General Announcements

Slide 4

Division of Basic Neuroscience

Chief: Joseph T. Coyle, MD

(Effective October 1, 2010)

New Division

New Federal Grants since January 1, 2010

S. Andersen: R01

Early drug exposure and drug reward mechanisms

 

D. Balu: F32

Molecular Mechanisms of Dendritic Abnormalities Related to D-Serine Deficiency

 

V. Bolshakov: R01

Synaptic mechanisms in extinction of conditioned fear

 

V. Bolshakov: R03

Functional role of vesicular zinc in synaptic mechanisms in the amygdale

 

E. Chartoff: R01

Role of dopamine signaling in the mood-related effects of salvinorin A

 

M. Copersino: K23

Multimodal Brain Imaging of Functional Neurodyynamics in Cocaine Dependence

 

B. Frederick: S10

4 Tesla MR Spectroscopy Console Upgrade

 Slide 5

New Federal Grants since January 1, 2010

Slide 6

B. Frederick: R21

Real time near infrared spectroscopy of the frontal lobe for Neurofeedback

M. Hall: K01

Functional Characterization of Risk Variants for Psychotic Illness in the GWA Er

 

E. Jensen: R21

Proton Echo-Planar Spectroscopic Imaging of GABA, Glutamate/Glutamine at 4 Tesla

 

R. Karmacharya: K08

Wnt/GSK3/ beta-Catenin Singaling as a Target for Treatment of Bipolar Disorder

 

K. Kim: R01

Protein-induced human iPS cells for personalized cell therapy for PD

 

N. Mello: R01

Sex/gender and nicotine addiction: hormones, behavior and neuroimaging

 

K. Myers: K01

NMDA receptor-mediated plasticity in extinction of conditioned opiate withdrawal

 

New Federal Grants since January 1, 2010

G. Noam: NSF

Empirical- Development of an Observation Tool for the Informal Science Field

 

U. Rudolph: R21

Generation of etiological models for schizophrenia by chromosome engineering

 

M. Silveri: R01

Neurobiological consequences of binge alcohol consumption in young adults

 

M. Silveri: R21

Sex Differences and Alcohol Dependence: Hippocampal Neurochemistry and Function

 

M. Teicher: R01

Sensitive Periods, Brain Development and Depression

 

M. Thomsen: K99

Elective muscarinic receptor ligands as targets for cocaine addiction medication

 

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Slide 8

Research Portfolio Management

McLean Research

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McLean Research: Portfolio Management

In order to enhance research portfolio management and to reduce research fund deficits:

Enhance financial reports, tools and oversight processes for improved fund management and more accurate and timely identification of fund in deficit and at imminent risk of deficit

Update, communicate and ensure compliance with policies and procedures

Improve communication between Research Administration and McLean research community

Expand support of researchers

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McLean Research: Portfolio Management

Enhance financial reports, tools and oversight processes for improved portfolio and fund management and more accurate and timely identification of fund in deficit and at imminent risk of deficit

1. Reports for McLean PIs, Research Administration and Finance

a) Insight financial reports

b) InfoEd – Proposal Tracking; Proposal Development

2. Re-mapping of Chief of Service codes

3. Processes

a) Resource projections annually by lab

b) Regularly recurring tracking of fund balances and burn rates by Research Administration and Finance Early warning to PIs as needed

Research Fund Management Initiative

Update, communicate and ensure compliance with policies and procedures

1. Review, clarify and update policies and proceduresa) Simplify when possible

2. Develop manual that includes:a) Detailed responsibilities of PI, lab-based research administrators

and Research Administrationb) Checklists for PIs and grant managersc) Procedure flow chartsd) Organizational chart

3. Provide contacts who can offer support and guidance

4. Make information more easily accessiblea) Research Intranet (research.mclean.harvard.edu)

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Research Fund Management Initiative

Improve communication between Research Administration and McLean research community

Optimize use of modes of communication

1. Research Intranet

2. Email

3. Departmental Research Administrators Workgroup (DRAW)

4. Research Committee

5. Mailman Research Center Steering Committee

6. Research Town Meeting

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Research Fund Management Initiative

Expand support of researchers

1. Continue Research Admin open door policy for PIs and administrators in addition to regular office hours for: Pre-award Time and effort reporting Post-award Research Finance Portfolio management

2. Enhance training

a) New PIs

b) Lab-based research administrators

c) General research community

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Slide 14

Grant Oversight

Grant Administration Competencies

McLean Research

Slide 15

McLean Research

Goal: Ensure that all PI’s and research grant administrators at McLean Hospital have requisite knowledge and skills to manage their grants.

Advisory Committees: DA’s (DA’s and PI’s) PI’s (PI’s)

Training Assessment and feedback

Slide 16

McLean Research

Changing Research Landscape:

Increasing complexity of federal regulations Public demand for research accountability / transparency Significant audits / settlements

Greater scrutiny Effort reporting Cost Allocation Cost transfers Unallowable costs Subrecipient monitoring Delinquent reporting to sponsor

Slide 17

McLean Research

Principal Investigators:

Roles and Responsibilities Scientific Integrity Effort and Salary Financial Oversight Conflict of Interest

http://phsresearchintranet.partners.org/PHS_ResearchMgmt/PHSResearchCompliance-PIQuickGuide.asp

Slide 18

McLean Research

Department Administrators:

Roles and Responsibilities Pre-Award, Progress Report Documents Subcontracts Allowable Costs Income & Expense Effort Reporting

http://phsresearchintranet.partners.org/PHS_ResearchMgmt/PHSResearchCompliance-DAQuickGuide.asp

Slide 19

McLean Research

Questions Open Forum

Slide 20

McLean Research

Presentation

2010

Anne M. Cataldo

Excellence in Mentoring Award to

Ross J. Baldessarini, MD