Slide No 1 • •

Corporate Social Responsibility

Lars Rebien Sørensen

CEO

Novo Nordisk A/S

Board Member

World Diabetes Foundation

The number of people with diabetes in the world is expected to rise from 177 million today to 370 million in 2030

76% of the total number of people with diabetes worldwide will be living in the developing countries

The developing countries carry 90% of this world’s total disease burden, yet they benefit from only 10% of global health resources

WHO estimates that 1/3 of the world population lacks regular access to essential drugs, and this figure is expected to rise to over 50% in the least developed parts of Africa and Asia

WHO states that non-communicable diseases such as diabetes are the world’s main disablers and killers already now

Slide No 5 • •

Epidemiology: Burden of diabetes is increasing

• Increased childhood and adult obesity• Decreasing levels of physical activity• Increasing urbanisation• Increased longevity• Earlier diagnosis

A new patient is diagnosed with type 2 diabetes every 5 minutes

Epidemic(WHO, 1997)

Slide No 6 • •

The sufferings from diabetes

• Life expectancy is reduced by 5 to 10 years

• Premature death due to myocardial disease X 4

• Stroke is increased X 2

• Renal failure: 40% of all dialysed patients have diabetes

• New blindness: 30% of all cases are people with diabetes (>90% of these have type 2 diabetes)

• Two out of three amputees have diabetes

Slide No 7 • •

The financial costs of diabetes

”With the present trend diabetes and its complications, will take more than one third of the health budgets in only 15 to 20 years – if vigorous steps to slow theprogress of this ’epidemic’ are not taken”

S. Orahilly, Science, medicine and the future. Non-insulin-dependent diabetes mellitus: the gathering storm. BMJ March 1997

Slide No 8 • •

What can a diabetes company do?

Slide No 9 • •

• Financial• Socio-& health economics

• Employees • Patients• Communities

•Environment• Animals• Bioethics

Economically viable

Environmentally soundSocially responsible

The Triple Bottom Line

Slide No 10 • •

Access to health in developing countries

WHO recommendations:

• Development of national health strategies

• Building of national healthcare capacity

• Best possible pricing

• Additional funding

Slide No 11 • •

Diabetes a national priority?

Slide No 12 • •

Diabetes prevention programme

NCD Unit for prevention /control

National survey for hypertension

No surveillance system nationally

NCD policy

Budget line for NCD

Integrated primary care prevention

NCD info in annual report

Focus on chronic diseases? (167 countries)

Alwan 2001

Slide No 13 • •

National Diabetes Strategies programme

• Novo Nordisk facilitates development and collaboration on the implementation of national strategies for diabetes prevention and treatment

• We aim at identifying best practices from around the world

• The programme is systematic and can be a template for the other chronic diseases (CVD, hypertension)

Slide No 14 • •

Understanding patients needs

Slide No 15 • •

DAWN- A study to understand…

• People with diabetes • Feelings, worries,

wishes and needs

• Perceptions of their diabetes

• Health care professional attitudes

• Role of psychosocial factors

Slide No 16 • •

Best Pricing

Slide No 17 • •

Pricing Policy in LDC Countries

• Novo Nordisk offers its insulin products to the public health systems in the poorest countries at prices not to exceed 20% of the average price in North America, Europe and Japan

LDC as defined by UN: 49 countries in Africa, Asia-Pacificand Central America

Slide No 18 • •

Additional funding

The World Diabetes Foundation founded in March2002

Initiated by a grant from Novo Nordisk of USD 80 million Majority of board members – non Novo NordiskChairman: Professor Pierre Lefèbvre26 projects funded to date

WDF is dedicated to prevention and treatment of diabetes in the poorest countries with focus on:

Awareness about diabetesPrevention of diabetes and its complications Education and training for patients and professionalsAccess to essential diabetes medicationDetection, treatment and monitoring of diabetes

The role of the World Diabetes Foundation

Creates partnerships and acts as a catalyst

Links people and resources to advocate globally and provide care locally

Aims at the poorest of the poor

Focuses on innovative strategies to prevent diabetes

Strives to achieve sustainable solutions

Regional projects in WDF portfolio

• Diabetes Education, Sub-Saharan Africa• Clinical Practice Guidelines, Sub-Saharan Africa• WDF/IDF Fellowships• Nutrition Protocol, the Caribbean• Postgraduate diabetes training, Africa

Local projects in WDF portfolio

• Cameroon: National Diabetes Programme• China: National Diabetes Programme• India: Diabetes Eye Care• India: National Diabetes Programme• India/Tanzania: Diabetes Foot Care• India: Rural and semi-urban diabetes

prevention and control• Tanzania: 15 Diabetes Clinics• Mozambique: Insulin Availability • West Bank: Diabetes Prevention and Nutrition• Cuba: Regional Diabetes Centers • Congo / Kinshasa: Insulin Availability• Vietnam: National Diabetes Project • Bolivia: Diabetes Centre• Nepal: Diabetes Education and Prevention• Bhutan: Diabetes health care services• Pacific Islands: Reducing diabetes

complications

Memorandum of Understanding with DANIDAMemorandum of Understanding with DANIDA- Danish International Development Agency- Danish International Development Agency

The objective of the partnership is to combat diabetes in the developing countries

Lead to the identification of two projects in India and Bhutan

Application criteriaApplication criteria

SustainabilityLocal championPolitical willCo-fundingApplication form on www.worlddiabetesfoundation.org

Multiplier effectMultiplier effect

Project portfolio:21 million USD of which 12 million USD were donated by the World Diabetes Foundation

ImpactImpact

The projects funded by the World Diabetes Foundation will in the coming 3-4 years potentially influence the diabetes treatment of 18,000.000 people directly and indirectly 50,000,000 people in the developing countries

Slide No 29 • •

“The hottest places in Hellare reserved for those who,in time of great moral crisis,maintain their neutrality” Dante

Slide No 30 • •

“…Governments only find the courage and resources to do the right thing whenbusiness takes the lead.”

Kofi Annan

Slide No 31 • •

Need for a new and different understanding of the disease

Need for a new social equation in disease management

An urgent need that governments, scientists, corporations, patients join forces against the disease

Thank you!