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Small for gestational age
Dr.V.RavimohanSpR
• Definition
• Implications
• Causes
• Diagnosis
• management
Definition
SGA refers to a fetus that has failed to achieve a specific biometric or estimated weight threshold by a specific gestational age.
10 th centile
Abdominal circumference
Estimated fetal weight
One of most frequently sited suboptimal care is the failure
to suspect growth restriction in a mother with a previous history
to detect to act on to monitor
Implications
• stillbirth
• birth hypoxia
• neonatal complications
• Neurodevelopment delay
• type 2 (non-insulin-dependent) diabetes and hypertension in adult life.
Small for gestational babies
Fetal growth restriction
30%
constituninal small babies
70%
constituninal small babies
Fetal growth restriction
Small for gestational babies
constitutional70%
Fetal growth restriction
30%constitutional
Fetal growth restriction
Ott Wj.The diagnosis of altered fetal growth.Obstet Gynecol Clin North Am 1988;15:237-63Ott Wj.The diagnosis of altered fetal growth.Obstet Gynecol Clin North Am 1988;15:237-63
population sensitivity specificity
SFH General 27% 88%
customised fundal chart
General 48%
ultrasound scan biometry(AC)
High risk 72.9–94.5% 50.6–83.8%
Improving sensitivity…
– Use customised ultrasound charts(maternal weight, maternal height, ethnic group and parity)
– Use growth velocity in addition to size
biometric testsbiometric tests biophysical testsbiophysical tests
designed to predict size fetal wellbeing
•abdominal palpation •symphyseal fundal height •ultrasound biometry•ultrasound estimated fetal weight
•Doppler•Amniotic fluid index•CTG
diagnosis of SGA more indicative of FGR than SGA
Management
• (I) aetiology(ex.chromosomal defects)
• (ii)arrange surveillance
• (iii) delivery-» when? » how? » where?
Causes of Growth restriction
54%
20%
12%
8%6%
Severe UP dysfuction
Chromosomal abnormality
Structural malformation
Congenital infection
miscellaneous
High risk pregnancy management options 2nd edition p300High risk pregnancy management options 2nd edition p300
Chromosomal abnormalities
10 th Centile 7%
5thCentile 19%
Surveillance
• Umbilical artery doppler is the primary surveillance tool– frequency of monitoring in SGA fetuses
with normal Doppler need not generally be more than once every fortnight.
Doppler indices
S/D ratio Systolic peak velocity
diastolic peak velocity
Resistance index Systolic-end diastolic peak velocity
systolic peak velocity
Pulsatility index Systolic-end diastolic peak velocity
Mean systolic velocity
Doppler
Absent/Reverse EDFEDF present
Delay delivey till 37w*
>34 weeksdeliver
<34 weeks(i)Admission
(ii)Closed surveillance(iii)steroids
<34 weeks with RED/AED
• Daily CTG/Biophysical profile/Venous doppler
• Consider delivery » Pathological CTG» Biophysical score <4» Reversal of doppler velocities in ductus venosus
during atrial contraction or umbilical vein pulsations
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• MY blog :http://mrcogfacts.blogspot.com/
Survival by birth weight
Survival by gestation
Growth Restriction Intervention Trial (GRIT)
• Hypothesis:early delivery,to pre-empt intrauterine hypoxia,would alter brain development compared with delaying delivery for as long as possible ,to gain maturity.
588 babies(fetal compromise
between 24-36 weeks)
Immediate delivery(296)
Delivery when obstetrician no longer uncertain
(292)
OR 1.1(0.7-1.8)
Im m ed ia te d e live ry 5 5(1 9 % ) D e la yed d e live ry 4 4 (1 6 % )
D e a th a n d se ve re d isa b ility a t 2 yrs
Conclusion
• The present study should discourage doctors who deliver fetuses (<30 weeks) before at which they delivery can be delayed no longer.
Mode of delivery
Indications for LSCS
(I)late decelerations in antenatal CTG
(II)Reversed End diastolic flow
(III)thick meconium during induction of labour
Clinical obstetrics and Gynaecology 40:4:1997;p822
Summary
• Definition
• Implications
• Causes
• Diagnosis
• management