CURRICULUM VITAE Christopher M.J. Cain, MBBS, MD (Adel), FRACS (Orth), FAOrthA Personal History : Current Position: Associate Professor University of Colorado at Denver Mail Stop B202 12631 East 17 th Avenue, Room 4611 Aurora, CO 80045 Office: 303-724-8936 Fax: 303-724-1593 Cell: 303-727-0529 Email: [email protected]Citizenship: Australia United States America Education : Undergraduate: University of Adelaide; Jan 1979 – Dec 1984 North Terrace Adelaide SA 5005 AUSTRALIA Bachelor of Medicine, Bachelor of Surgery (equivalent to MD in US) Post Graduate: University of Adelaide; Awarded Oct 11 th ,1993 North Terrace Adelaide SA 5005 AUSTRALIA Doctor of Medicine (equivalent to PhD in US) Internship: Queen Elizabeth Hospital; Jan 1985 – Jan 1986 28 Woodville Road Woodville South SA 5011 AUSTRALIA Basic Surgical Training: Queen Elizabeth Hospital; Feb 1986 – Feb 1987 28 Woodville Road Woodville South SA 5011 AUSTRALIA Neurosurgical Residency: Queen Elizabeth Hospital; Feb 1987 – Feb 1988 28 Woodville Road
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CURRICULUM VITAE
Christopher M.J. Cain, MBBS, MD (Adel), FRACS (Orth), FAOrthAPersonal History:
Current Position: Associate ProfessorUniversity of Colorado at DenverMail Stop B20212631 East 17th Avenue, Room 4611Aurora, CO 80045
Education: Undergraduate: University of Adelaide; Jan 1979 – Dec 1984
North TerraceAdelaide SA 5005AUSTRALIABachelor of Medicine, Bachelor of Surgery (equivalent to MD in US)
Post Graduate: University of Adelaide; Awarded Oct 11th,1993North TerraceAdelaide SA 5005AUSTRALIADoctor of Medicine (equivalent to PhD in US)
Internship: Queen Elizabeth Hospital; Jan 1985 – Jan 198628 Woodville RoadWoodville South SA 5011AUSTRALIA
Basic Surgical Training: Queen Elizabeth Hospital; Feb 1986 – Feb 198728 Woodville RoadWoodville South SA 5011AUSTRALIA
Neurosurgical Residency: Queen Elizabeth Hospital; Feb 1987 – Feb 198828 Woodville RoadWoodville South SA 5011AUSTRALIAAlso worked at Women’s & Children’s Hospital as the Neurosurgical Resident and undertook research to assess the incidence of significant cervical injuries in road accident fatalities, and the morbidity associated with cervical flexion/extension injuries with the National Health & Medical Research Council Road Accident Research Unit during this period
Clinical Research Fellow: Royal Adelaide Hospital; Feb 1988 – Feb 1989Spine UnitDepartment of Orthopedics & TraumaLevel 4, Bice BuildingNorth TerraceAdelaide SA 5000AUSTRALIA
Orthopedic Residency: Australian Orthopedic Association; Feb 1989 – Jan 1994Level 1245 Clarence StreetSydney NSW 2000AUSTRALIAOffice: +61 2 8071 8000Fax: +61 2 8071 8002Email: [email protected]
Accredited by: Royal Australasian College of SurgeonsCollege of Surgeons’ Gardens250-290 Spring StreetEast Melbourne VIC 3002AUSTRALIAOffice: +61 3 9249 1200Fax: +61 3 9249 1219Email: [email protected]
Clinical rotations in 6-month blocks between the 4 hospitals listed below.
Royal Adelaide HospitalDepartment of Orthopedics & TraumaLevel 4, Bice BuildingNorth TerraceAdelaide SA 5000AUSTRALIA
Flinders Medical CentreDepartment of Orthopedics & TraumaBedford Park SA 5042AUSTRALIA
Queen Elizabeth Hospital28 Woodville RoadWoodville South SA 5011AUSTRALIA
Women’s & Children’s Hospital72 King William RoadNorth Adelaide SA 5006AUSTRALIA
Fellowship Training:Sept 1993 - Aug 1994 Supervisor/Mentor: Mr John K. Webb
University HospitalQueens Medical CentreDerby RoadNottingham NG7 2UHUNITED KINGDOM
Aug 1994 - Sept 1994 AO Spine FellowDr Fritz Margerl & Dr Bernard JeanneretKantonsspital St GallenSWITZERLAND
Academic Appointments: Jan 1999 - Jun 2010 Clinical Lecturer
Faculty of Health SciencesUniversity of AdelaideNorth TerraceAdelaide SA 5005AUSTRALIAPhone: +61 8 8303 5277Fax: +61 8 8303 4360Email: [email protected]
Oct 2010 - Current Associate ProfessorDepartment of OrthopedicsUniversity of Colorado Denver12631 E. 17th Avenue, Mail Stop B202Academic Office 1, Room 4611Aurora CO 80045Phone: +1 303 724 2958Fax: + 303 724 2977Email: [email protected]
Professional Appointments: Oct 1994 - Jun 1997 Visiting Medical Specialist
Department of OrthopaedicsFlinders Medical CentreBedford ParkSouth Australia
Jul 1997- Dec 1999 Senior Visiting Medical SpecialistDepartment of OrthopaedicsFlinders Medical CentreBedford ParkSouth Australia
Oct 1994 - Feb 1998 Visiting Medical SpecialistDepartment of Orthopaedic Surgery & TraumaRoyal Adelaide HospitalNorth Terrace, AdelaideSouth Australia
Feb 1998 - Jun 2010 Senior Visiting Medical SpecialistDepartment of Orthopaedic Surgery & TraumaRoyal Adelaide HospitalNorth Terrace, AdelaideSouth Australia
Oct 1994 - Jun 2010 Visiting Orthopaedic SpecialistWakefield Private Hospital300 Wakefield StreetAdelaide 5000South Australia
Oct 1994 - June 2010 Visiting Orthopaedic SpecialistMemorial Private HospitalSir Edwin Smith AvenueNorth Adelaide 5006South Australia
Jul 1997 - Jun 1999 Honorary Visiting Medical Specialist (Unpaid)Women’s & Children’s Hospital72 King William RoadNorth Adelaide 5006South Australia
Jul 1999 - Jun 2010 Senior Visiting Medical SpecialistWomen’s & Children’s Hospital72 King William RoadNorth Adelaide 5006South Australia
Nov 1997 - June 2010 Visiting Orthopaedic SpecialistSt Andrews Private Hospital350 South TerraceAdelaide 5000South Australia
Oct 2010 - Current Associate ProfessorDepartment of OrthopedicsUniversity of Colorado Denver12631 E. 17th Avenue, Mail Stop B202Academic Office 1, Room 4611Aurora CO 80045Phone: +1 303 724 8936Fax: +1 303 724 1593Email: [email protected]
Awards and Honors:1986 - 2003 Royal Australian Army Medical Corps - Reserve
(Promoted to rank of Major)
1990 Rob Johnston AwardBest Paper, Annual Scientific Meeting of the Spine Society of Australia, July 1990, Sydney
1990 Censor-in-Chief's PrizeBest Paper: Australian Orthopaedic RegistrarsAssociation Conference
1991 Censor-in-Chief's PrizeSecond Place: Australian Orthopaedic Registrars Association Conference
1993 Smith & Nephew Richards Academic PrizeAwarded by the Australian Orthopaedic Association
2003 President’s Award, Australian Medical Association
2007 Marquis Who’s Who in the World24th Edition
2011 AOSpine “Oscar” – Educational Excellence Award (Asia Pacific)
Membership in Professional Organizations:1985 - Dec 2012 Australian Medical Association
1990 - Dec 2012 Spine Society of Australia
1993 - Current AO Alumni
1994 - Current Australian Orthopaedic Association
1994 - Current Royal Australasian College of Surgeons
1994 - 2010 Australian Society of Orthopaedic Surgeons
1996 - Current AOSpine International Faculty Member
2011 - Current North American Spine Society
2011 - Current The International Society of Orthopedic Surgery and Traumatology
Committee and Service Responsibilities: Local Committees and Service Activities:
Nov 1997- Jul 1999 Executive member, Association for the Advancement of Private Health
May 2005 - May 2007 Member Credentialing Committee St Andrews Private Hospital
May 2014 - June 2015 Promotions Committee, University of Colorado, Denver, Department of Orthopaedics
May 2016 - Jan 2018 University of Colorado Hospital, Strategic Sourcing Committee
June 2011 – Current Spine Service Curriculum committee representative Resident training, University of Colorado, Denver
June 2015 - Current Chairman Promotions Committee, Department of Orthopaedics, University of Colorado, Denver
June 2015 - Current Finance Committee, Department of Orthopaedics, University of Colorado, Denver
April 2019 - Current Governance Taskforce, Department of Orthopaedics, University of Colorado, Denver
State Committees and Service Activities:Aug 1996 - Aug 1998 Secretary Treasurer, Australian Society of
Orthopaedic Surgeons, South Australian BranchAug 1998 - Aug 2002 Chairman Australian Society of Orthopaedic
Surgeons, South Australia Branch Jun 2001 - Jun 2003 Seconded Member, Royal Australasian College of
Surgeons Council, South Australian Regional Board May 2001 - May 2003 Australian Medical Association, South Australia
Surgical Craft Group RepresentativeJun 2003 - May 2005 Vice President, Australian Medical Association
South AustraliaMay 2005 - May 2007 President, Australian Medical Association
South AustraliaMar 2007 - Jun 2010 South Australian Department of Health, Clinical
Network Chairman – OrthopaedicsJun 2007 - Jun 2010 Member Clinical Senate – Department of HealthJul 2007 - Jun 2010 Specialist Medical Advisor – Chief Executive
Department of Health & Minister of Health, South Australian Government
Apr 2008 - June 2010 Chair Physician Assistant Implementation and Evaluation Trail Oversight Committee, South Australian Department of Health
National Committees and Service ActivitiesAug 1996- Aug 1999 Treasurer, Australian Society of Orthopaedic Surgeons
Jun 2002 - Aug 2007 South Australian representative, Australian Medical Association Federal Council & Director AMA Ltd.
Aug 2003 - Aug 2007 Director AMA Commercial Ltd.Apr 2004 - Aug 2007 Chair, Australian Medical Association
National Risk Management Working Party
Apr 2005 - Aug 2007 Royal Australasian College of Surgeons Nominee, Federal Government “Spine Prosthesis Clinical Consultative Group” Prosthesis & Device Committee
Jun 2005 - May 2007 Executive Council, Australian Medical AssociationMay 2006 - Aug 2007 Director Australian Medical Publishing Co.
International Committees and Service ActivitiesOct 2003 - Dec 2005 Chairman, AOSpine Australia/New ZealandDec 2003 - Dec 2005 Educational Director and Board Member AOSpine
Asia PacificDec 2003 - Dec 2006 Member AOSpine International Education
CommissionAug 2010 – July 2013 Educational Director, and Board Member AOSpine
Asia PacificAug 2010 – July 2013 Member AOSpine International Education
Commission
Licensures and Certifications: Certifications:
Australian Orthopaedic AssociationAffiliate 1990 - 1993Associate member 1993 - 1997Full Member 1997 - Current
Fellow Royal Australasian College of Surgeons Feb 1994 - Current
Licensures:Medical Boards Australia
Registration Number: MED0001403352 Provisional Registration Jan 1985 - Jan 1986 (Internship)General Medical Registration Feb 1986 - Jan 1994Specialist Medical Registration - Orthopaedic Surgery Feb 1994 - Current
Colorado Medical BoardForeign Teaching Physician - TDP-1025Issue date: 8/18/2010
Federal DEA LicenseNo: FC2267739
Inventions and Patents:1. US 5,368,044 A “Vibration analysis of bones”
Date of Patent: Nov 29, 1994
2. US 7,232,464 B2 “Intervertebral Implant”Date of Patent: Jun. 19, 2007
3. US 7,618,456 B2 “Intervertebral Implant”Date of Patent: Nov. 17, 2009
4. US 7,875,076 B2 “Intervertebral Implant”Date of Patent: Jan. 25, 2011
5. US 8,709,085 B2 “Intervertebral ImplantDate of Patent: April 29, 2014
6. US 8,715,354 B2 “Intervertebral Implant”Date of Patent: May 6, 2014
7. US 8,936,641 B2 “Expandable Intervertebral Implant”Date of Patent: Jan. 20, 2015
8. US 9,155,564 B2 “Spine Stabilization System and Method”Date of Patent: Oct. 13, 2015
9. US 9,41,4934 B2 “Expandable intervertebral implant” Date of Patent: Aug 16, 2016
10.US 9,463,097 B2 “Intervertebral implant”Date of Patent: Oct 11, 2016
11.US 9,526,625 B2 “Expandable intervertebral implant”Date of Patent: Dec 27, 2016
12.US 9,545,314 B2 “Expandable intervertebral implant”Date of Patent: Jan 17, 2017
13.US 9,572,681 B2 “Intervertebral implant”Date of Patent: Feb 21, 2017
14.US 9,597,195 B2 “Expandable intervertebral implant”Date of Patent: March 21, 2017
15.US 9,549,822 B2 “Vertebral body replacement or fusion device”Date of Patent: Jan 24, 2017
Patents Pending:1. Patent Pending – “Mono to Poly Axial Universal Pedicle Screw and Method of using the
same”International Application Number: PCT/US18/22761Receipt Date: Mar. 15 2018
2. Patent Pending – “Dispositif de replacement ou de fusion de corps vertebral“European Patent Office : EP2991590A1International Application Number : PCT/US2014/035779Publication Date : Mar. 9 2016
Faculty Australian Orthopaedic Association Annual Scientific Meeting – Spine Section, Perth, Australia, October 2005
Faculty AOSpine Interactive & Masters course, Davos, Switzerland, December 2005
Lumbar Degenerative Disease Seminar, International Meeting of Advanced Spine Technologies, Athens, Greece, July 2006
International Chairman AOSpine Interactive Course Tokyo, Japan, October 2006
13th Asia Pacific Orthopaedic Association Operative Spine Course, Coimbatore, India, March 2007 - Faculty & live surgery demonstration.
Poster presentation, International Society for the Study of the Lumbar Spine Meeting, Bergen, Norway, June 2006. "Clinical and Radiological outcomes of a Stand-Alone Anterior Fusion Cage with Integrated Screw Fixation: One year results" Bernard LaRue, Russell Morcom, David Hall, Christopher Cain
Faculty AOSpine North America Meeting Niagara on the lake, Ontario Canada, August 2007
International Chairman Anterior Lumbar Access Course, Hong Kong, September 2007
Lumbar Degenerative Disease Seminar, North American Spine Society Meeting, Austin, Texas, October 2007.
Presentation, Global Spine Congress, San Francisco, June 2008. "Clinical and Radiological outcomes of Stand-Alone Anterior Lumbar Interbody Fusion: Two year results" Christopher Cain, David Ardern,, Martin Wilby, Simon Tizzard, Bernard Larue, Russell Morcom, David Hall
Poster presentation, North American Spine Society Meeting, Toronto, Canada, October 2008. "Clinical and Radiological outcomes of Stand-Alone Anterior Lumbar Interbody Fusion: Two year results" Christopher Cain, David Ardern,, Martin Wilby, Simon Tizzard, Bernard Larue, Russell Morcom, David Hall
International Faculty, AOSpine Regional Seminar "Surgical Treatment of Deformity" Tokyo, Japan, June 2010
Presidential Guest, Chilian Orthopaedic Association Annual MeetingLa Serena, Chile, November 2010
Faculty and presenter, AOSpine Global Spine Congress, Barcelona, Spain March 2011
International Chairman, AOSpine “Teach the Teachers” Course, Shanghai, China, May 2011
International Chairman, AOSpine “Teach the Teachers” Course, Seoul, Korea, June 2011
Faculty, AOSpine Anatomical Specimen Workshop, Lucern, Switzerland, December 2012
International Faculty Global Spine Congress, Hong Kong, April 2013
Chairman, AOSpine Training for Chairpersons & Education Advisors, Shanghai, April 2013
Chairman, AOSpine Training for Chairpersons, Asia Pacific Faculty, Hong Kong, May 2013
Chairman, AOSpine Training for Faculty & Chairpersons, Asia Pacific Faculty, Hong Kong, October 2013
International Facutly “Degenerative Lumbar & Cervical Spine Modules” AOSpine Advanced Courses, Davos, Switzerland, December 2013
Chairman & Principle Faculty, AOSpine Principles and Masters Courses, Nepal, Kathmandu, February 2014
Chairman, AOSpine Training for Faculty, Asia Pacific Faculty, Hong Kong, June 2014
International Faculty, AOSpine Cadaver Course, Melbourne, Australia, August 2014
International Faculty, AOSpine Advances Course, Yokohama, Japan, September 2014
Chairman, AOSpine Traning for Chairpersons, Asia Pacific Faculty, Hong Kong, October 2014
Preoperative Coagulation Profile Testing to Predict Blood Loss in Complex Spine Surgery: Identifying the Patient at Risk. 29th Annual Meeting of the North American Spine Society. San Francisco, California, November 2014.
Patient-specific templating for ADR identifies factors that influence clinical outcomes. 15th Annual Meeting of The International Society for the Advancement of Spine Surgery. San Diego, California, April 15-17, 2015
Education Advisor, AOSpine Masters Course, Hong Kong, September 2015
A Surgeons Experience with Product Development, Asia Pacific Spine Symposium, Hong Kong, September 2015
A Comparative Analysis of Lumbo-Sacral Fixation, What is best in a long fusion. International Society for the Advancement of Spine Surgery, Las Vegas April 6-8 2016
Risk Factors Associated with Mechanical Complications Including Proximal Junctional Failure after Osteotomy for Adult Spinal Deformity. International Society for the Advancement of Spine Surgery, Las Vegas April 6-8 2016
What is the Clinical Relevance of Nonunion after Lumbar Arthrodesis? A Meta-analysis of the YODA Project Database. International Society for the Advancement of Spine Surgery, Las Vegas April 6-8 2016
“Stand Alone” ALIF; Does biomechanics matter and how does it influence fusion outcomes. North American Spine Society Annual Meeting, October 27th 2016
Benefits and Biomechanics of Stand Alone ALIF. Anterior Access Course, Raynham MA June 16 2017
Anterior access lumbar spine - surgical technique and video demonsration. Anterior Access Course, Raynham MA June 16 2017
Visiting Professor – “Spine surgery – the US and Australian perspectives”, The International Spine Centre, Adelaide, South Australia, September 21, 2017
Chariman Anterior access lumbar spine – Indications, surgical technique, video demonsration and cadaver workshop. Anterior Access Course, Raynham MA August 18 2018
Lectures Topics Delivered Nationally & Internationally:ALIF Indications and Techniques
AO Classification of Fractures Thoraco-Lumbar spine
Classification of Cervical Fractures C1-C7
Classification of Upper Cervical Injuries
Indications for Surgery Thoraco-Lumbar Fractures
IDET: A Prospective Randomised Trial
Spinal Canal Stenosis: Indications for Fusion
Central Cord Syndrome: Case for Intervention
Choosing Levels in Scoliosis
Surgery for Kyphotic Deformities
Surgical Management of Ankylosing Spondylitis & Kyphosis
Management of Neoplastic Disease of the Spine
Cervical Laminectomy vs Laminoplasty
Osteoporotic Fractures: Short vs Long Fixation
Postero-Lateral Fusion Indications and Technique
USS Concept and Technique
Degenerative Scoliosis
Short Segment Fixation Thoraco-Lumbar Fractures Without Fusion
Controversies in the Management of Cervical Spine Trauma
Anterior Lumbar Cage Design and Development
“Stand Alone” Lumbar Fusion: Technique and Results
Anterior Lumbar Fusion: Historical Perspective
Motion Preservation: Myth or Magic?
Anterior Lumbar Fusion: Indication and Results
Bracing is Out-dated Treatment for Scoliosis
Management of Adult Spinal Deformity
Universal Spine System Concept and Technique
Adjacent Segment: Avoiding Problems
Axial Back Pain: Non-Operative Management
Backs, Necks and Pain: A Primer for Non-surgeons
Management of the Degenerative Lumbar Spine: Past, Present & Future
Discitis and Spinal Infection
Disorders of the Spine
Iatrogenic Spinal Cord Injury
Principles and Practice of Spine Surgery
Imaging of the Spine in the Spine Surgeons Assessment of Back Pain
Debate: TDR or Fusion – The Case for Fusion
Debate: New Technologies Produce Better Outcomes in the Treatment of Low Back Pain; The Case Against
Management of High Grade Spondylolisthesis
Cervical Cages: Stand Alone Results
Posterior Approaches to the Degenerate Cervical Spine
IDET & Nucleoplasty: The Evidence
Historical Review: Lumbar Interbody Fusion
Laparoscopic Anterior Interbody Fusion
360o Fusion: Implants, Techniques and Results, Can you Believe What you Read?
Sagittal and Coronal Balance
Laminectomy vs. Laminoplasty
Postero-Lateral Fusion: Inductions and Results
Spondylolisthesis, Is there a Need for PLIF or ALIF?
Thoraco-Lumbar Fractures: Anterior vs. Posterior?
Dealing with Complications in Spine Surgery
“Gaines Procedure” in High Grade Spondylolisthesis
Sagittal Balance and Pelvic Parameters
Management of Congenital Kypho-scoliosis
Considerations in the Management of Severe Adult Spinal Deformity
Anterior lumbar spine access, indications, complications and revision
Year Name Country of Origin1994/1995 Dr Simon Hadlow New Zealand1994/1995 Dr Mark Brown United Kingdom1995/1997 Dr Andrew Fagan Australia1995/1996 Dr Paul Sanderson United Kingdom1996 Dr Ciaran Bolger Ireland1996/1997 Dr Tim Love New Zealand1996/1997 Dr Bradley Weiner USA1997/1998 Dr Martin Newey United Kingdom1997/1998 Dr Thomas Egloff Switzerland1998/1999 Dr Mark Dolan Ireland1998/1999 Dr John Hutchinson Northern Ireland1999/2000 Dr Brian Freeman United Kingdom1999/2000 Dr Anant Kamat India2000/2001 Dr David Chapple United Kingdom2000/2001 Dr David Goss USA2001/2002 Dr Binod Singhania India2001/2002 Dr Edward Santos Philippines2002/2003 Dr Eugene Wai Canada2002/2003 Dr Guy Selmon United Kingdom2003/2004 Dr Ian Wright United Kingdom2003/2004 Dr Ed Yee New Zealand2004/2005 Dr Naffis Anjarwalla United Kingdom2004/2005 Dr John Burke Northern Ireland2005/2006 Dr Andrew Oakley New Zealand2005/2006 Dr Klas Halldin Sweden2006/2007 Dr Bernard LaRue Canada2006/2007 Dr Simon Tizzard United Kingdom2007/2008 Dr David Ardern New Zealand2007/2008 Dr Martin Wilby United Kingdom2008/2009 Dr Adam Meir United Kingdom2008/2009 Dr Jomick Lumawig Philippines2009/2010 Dr Guy Barham United Kingdom2009/2010 Dr Jeff Arbartin Philippines
Denver, Colorado:Year Name Country of Origin
2010/2011 Dr Hiroyuki Yashihara Japan2011/2012 Dr Matthew LaFleur USA2012/2013 Dr CJ Kleck USA2013/2014 Dr James Perry USA2014/2015 Khaled Zaghloul Egypt2015/2016 Dr David Ou-Yang USA2016/2017 Dr Nicholas Schroeder USA2016/2017 Dr Andrew Cleveland USA2017/2018 Dr Nolan Wessell USA2018 Dr Aaron Stevenson Australia2018/2019 Dr William McClellan USA
RESEARCH AND SCHOLARSHIP: 1. Doctoral Thesis: 1988 - 1993
"Assessment of spinal cord blood flow and function in sheep following antero-lateral cervical interbody fusion in animals with and without spinal cord injuries"
This research was conducted through the University of Adelaide in South Australia.
Supervisors: Professor Robert D FraserProfessor Donald Howie
Degree: Doctor of Medicine (Equivalent to PhD in USA) awarded October 11 th, 1993
A thesis for the award of post graduate doctoral degree of “Doctor of Medicine” at the University of Adelaide requires the candidate to demonstrate sound research principles and techniques, like that required for the award of a PhD, but has the added requirement of having to have made a significant contribution to medical science or understanding.
It was a requirement for enrolment that there be at least 12 months’ full time research, however, the remainder of the research, analysis and compilation of results could be undertaken on a part time basis.
2. Clinical ResearchClinical and research activities as Principle Investigator:1. Research project in collaboration with the Biomechanical Engineering
Department of the University of Denver, who have expertise in the field of Finite Element Analysis. The aim of the project is to identify and evaluate the biomechanical parameters contributing to the success, or failure, of lumbar total disc replacement.
Title: Pre-op Templating For TDR Alignment: Is It Clinically Relevant?COMIRB Protocol 12-1049 Effective Date: 28 Sep 2012Study completed Dec 2017
The results of this work have been presented at multiple international meetings since 2012 and resulted in three peer reviewed publications.
2. Industry sponsored study (SeaSpine) to assess the benefits, if any that exist related to the material used for cervical cage construction, comparing allograft bone to untreated PEEK and Titanium coated PEEK (NanoMetalene coating). This study is important to identify if any benefit exists as a number of companies report benefits in relation to achieving fusion success with the use of these coated implants. Companies charge a premium for implants coated with Titanium and if there is no clinical benefit conveyed by this process there would be no justification for their use, over cheaper alternatives.
Title: Comparison of Early Fusion Using he Cambria NanoMetalene Implant Verses Both PEEK and Allograft implants in Anterior Cervical Decompression and Fusion (ACDF) with OsteoStrand Demineralized Bone Fibers.
COMIRB Protocol 19-0313 Effective Date: 1 June 2019
Research activities as Co-Investigator:Title: A Prospective, Multi-Center, Randomized Study Comparing the Vertiflex Superion Interspinous Spacer (ISS) to the X-Stop Interspinous Process Decompression (IPD) System in Patients with Moderate Lumbar Spinal Stenosis COMIRB Protocol 08-0743
Title: Prospective Analysis of Spine Surgery OutcomesCOMIRB Protocol 10-0980
Title: Prospective Study of Pedicle Screw Placement Using the O-Arm and Navigated Instrumentation COMIRB Protocol 11-0990
Title: The Relationship Between Sagittal Plane Correction and Quality of Life in Adult Deformity Patients Treated with Posterior Instrumentation COMIRB Protocol 12-0483
Title: INSITE- Investigation of Sacroiliac Fusion Treatment COMIRB Protocol 12-1137
Title: Denver SI-Joint Questionnaire Validation Study COMIRB Protocol 13-0091
Title: Meta-analysis of the Outcomes and Complications in the Spinal Surgery Population Receiving Recombinant Human Bone Morphogenetic Protein-2 vs. Those Receiving Iliac Crest Bone GraftCOMIRB Protocol 13-3103
Title: Retrospective Review of Minimally Invasive Placement of Pedicle Screws in Spine SurgeryCOMIRB Protocol 14-0654
Title: Retrospective Review of Minimally Invasive Sacroiliac Joint Fusion using O-Arm and Stealth NavigationCOMIRB Protocol 14-0656
Title : Clinical and radiographic outcomes and cost effectiveness of stand-alone anterior lumbar interbody fusion versus transforaminal or posterior lumbar interbody fusion and 3260 degree fusions.COMIRB Protocol 14-0819
Title: Pedicle Screw Placement in Spine Surgery: A retrospective review of O-arm/Stealth vs Non-Computerized Navigation TechniquesCOMIRB Protocol 14-0873
Title: Analysis of prognostic cell signaling factors in Adolescent Idiopathic ScoliosisCOMIRB Protocol 14-0884
Title: Retrospective Review of Outcomes in Complex Spine SurgeryCOMIRB Protocol 14-1258
Title: A Double-Blind, Placebo-Controlled Crossover Study Comparing the Analgesic Efficacy of Cannabis versus OxycodoneCOMIRB Protocol 14-1909
Title: Quantification of the variable expression of estrogen receptors in human articular cartilage of healthy versus osteoarthritic females.COMIRB Protocol 14-1971
Title : A phase 2b, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of staphylococcus aureus 4-antigen vaccine (SA4Ag) in adults undergoing elective open posterior spinal fusion procedures with multilevel instrumentation. COMIRB Protocol 14-2273
Title: Prospective, Concurrently Controlled, Multi-Center Study to Evaluate the Safety and Effectiveness of the Spinal Kinetics™ M6-C Artificial Cervical Disc Compared to Anterior Cervical Discectomy and Fusion (ACDF) for the Treatment of Symptomatic Cervical RadiculopathyCOMIRB Protocol 14-2314
Title: Retrospective Review of Sacroiliac Joint Fusion RevisionsCOMIRB Protocol 15-0663
Title: Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers (EOS)COMIRB Protocol 15-2433
Title: Retrospective Review of surgical outcomes after planned rodCOMIRB Protocol 16-1619
Title: A phase 3, placebo-controlled, randomized, observer-blinded study to evaluate the efficacy, safety, and tolerability of a clostridium difficile vaccine in adults 50 years of age and older. COMIRB Protocol 16-2637
Title: Retrospective evaluation of post-operative wound-vac utilization following open spine surgeryCOMIRB Protocol 17-0683
Title: A Multi-Center, Open-Label, Prospective Study of SpinalStim™ (MOP-SS) as Adjunctive Care following Lumbar Fusion SurgeryCOMIRB Protocol 17-1037
Title: A Multi-Center, Open-Label, Prospective Study of CervicalStim device™ as Adjunctive Care following Cervical Fusion COMIRB Protocol 17-1013
Title: Changes in Opioid Prescription Use After Treatment with Spine FusionCOMIRB Protocol 17-1954
Title: Gait StudyCOMIRB Protocol 18-2822
Title: Comparison of Early Fusion Using the Cambria Nano-Metalene Implant Verses Both PEEK and Allograft implants in Anterior Cervical Decompression and Fusion (ACDF) with OsteoStrand Demineralized Bone Fibers Sponsor Protocol No. SS-NM-1801 WIRB Protocol No. 20190275COMIRB Protocol 19-0313
Title: Safety and Effectiveness of Bio2 Vitrium® Cervical Cage in Anterior Cervical Discectomy and Fusion. A Randomized, Controlled, Non-inferiority, Pivotal Study. Sponsor Protocol No. CT-17-001 WIRB Protocol No.COMIRB Protocol 19-0639
PODIUM PRESENTATIONS: (National or International 2012-2019) 1. Ayers R, Patel VV, Ou-Yang D, Cain CMJ, Pott MS, Burger EL, Kleck CJ. Laser marking as the
origin of spine rod fractures: A single Center Study. IMAST Amsterdam, July 17-20 2019
2. Kleck CJ, Noshchenko A, Cain CMJ, Burger EL, Patel VV. Evaluation of pelvic incidence (PI) constancy at different physiologic postures, and assessment of confounding factors that may affect stability of this parameter. Spine Society of Australia April 5-7 2019
3. Christopher J Kleck MD, Andriy Noshchenko PhD, Christopher MJ Cain MD, PhD, Evalina L. Burger MD, Professor, Vikas V Patel. Evaluation of pelvic incidence (PI) constancy at different physiologic postures, and assessment of confounding factors that may affect stability of this parameter. Annual Meeting of the Scolioisis Research Society (SRS). Bologna, Italy, October 10-13, 2018.
4. Fontan FR, Reeves B, Noshchenko A, Ou-Yang D, Kleck CJ, Cain CMJ, Burger EL, Patel VV. Strap stabilization used in posterior instrumented spinal fusion for proximal junctional kyphosis prevention: A retrospective cohort study. Orthopedic Research Society (ORS) New Orleans, March 10-13, 2
5. Lindley EM, Wuthrich ZR, Burger EL, Cain CMJ, Kleck CJ, Patel VV. Spine Fusion and rhBMP in a Vitamin D deficient rat model. Annual Meeting of the Intenational Society of Orthopaedic Surgery and Traumatology (SICOT). Cape Town, South Africa, November 30-December 2, 2017.
6. 3D Morphologic Assessment of Normal and Abnormal SI Joints and the Implications in the Development of Pain Syndromes. Annual Meeting of the International Society for the Advanacment of Spine Surgery (ISASS). Boca Raton, Forida, April 12-14, 2017.
7. An Evaluation of Standardized Bundles to Reduce Surgical Site Infections among Spine Patients. Annual Meeting of the International Society for the Advanacment of Spine Surgery (ISASS). Boca Raton, Forida, April 12-14, 2017
8. Bozzio AE, Johnson CR, Fattor JA, Kleck CJ, Patel VV, Burger EL, Noshchenko A, Cain CMJ. Clinical and Radiographic Outcomes of Stand-Alone Anterior Lumbar Interbody Fusion Versus Transforaminal Lumbar Interbody Fusions and 360-Degree Fusions. Annual Meeting of the Intenational Society of Orthopaedic Surgery and Traumatology (SICOT). Rome, Italy, September 8-10, 2016.
9. Combined antero-posterior approach does not increase the risk of proximal junctional kyphosis in adult spinal deformity. 23rd International Meeting on Advanced Spine Techniques (IMAST). Washington, DC, July 13-16 2016.
10. Cain CMJ, Noshchenko A, Lindley EM, Burger EL, Patel VV. What is the Clinical Relevance of Nonunion after Lumbar Arthrodesis? A Meta-Analysis of the YODA Project Database. Annual Meeting of the International Society for the Advanacment of Spine Surgery (ISASS). Las Vegas, Nevada, April 6-8, 2016.
11. Cain CMJ, Kleck CJ, Illing D, Lindley EM, Patel VV, Barton C, Baldini T, Burger EL. A Comparative Analysis of Lumbo-sacral Fixation Strengths: What is Best in a Long Fusion? Annual Meeting of the International Society for the Advanacment of Spine Surgery (ISASS). Las Vegas, Nevada, April 6-8, 2016.
12. Cain CMJ, Barton C, Noshchenko A, Patel VV, Kleck CJ, Burger EL. Risk Factors Associated with Rod Fracture After Osteotomy for Adult Spinal Deformity. Annual Meeting of the International Society for the Advanacment of Spine Surgery (ISASS). Las Vegas, Nevada, April 6-8, 2016.
13. Cain CMJ, Hollenbeck JFM, Fattor JA, Patel VV, Burger EL, Rullkoetter PJ. Patient-specific ROM Predicted by Pre-operative Templating after Total Disc Replacement
Surgery. Annual Meeting of the International Society for the Advanacment of Spine Surgery (ISASS). Las Vegas, Nevada, April 6-8, 2016.
14. Hollenbeck JFM, Cain CMJ, Fattor JA, Patel VV, Burger EL, Rullkoetter PJ. Pre-operative Templating for TDR Predicts Post-operative ROM and Could Improve Clinical Outcomes. Annual Meeting of the Orthopeadic Research Society (ORS). Orlando, Florida, March 5-8, 2016
15. Barton C, Noshchenko A, Patel V, Cain CMJ, Kleck CJ, Burger E. Risk Factors Associated with Rod Fracture After Osteotomy for Adult Spinal Deformity. Annual Meeting of the International Society of Orthopaedic Surgery and Traumatology (SICOT). Guangzhou, China, September 17-19, 2015.
16. Noshchenko N, Lindley EM, Burger EL, Cain CMJ, Patel VV. What is the Clinical Relevance of Nonunion after Lumbar Arthrodesis? A Meta-Analysis of the YODA Project Database. Annual Meeting of the International Society of Orthopaedic Surgery and Traumatology (SICOT). Guangzhou, China, September 17-19, 2015.
17. Burger EL, Barton C, Noshchenko A, Patel VV, Cain CMJ, Kleck CJ. Risk Factors Associated with Rod Fracture After Osteotomy for Adult Spinal Deformity. Annual Meeting of Eurospine. Copenhagen, Denmark, September 2-4, 2015.
18. Burger EL, Barton C, Noshchenko A, Patel VV, Cain CMJ, Kleck CJ. Risk Factors Associated with Mechanical Complications Including Proximal Junctional Failure after Osteotomy for Adult Spinal Deformity. Annual Meeting of Eurospine. Copenhagen, Denmark, September 2-4, 2015.
19. Cain CMJ, Burger EL, Illing D, Razavi-Shearer D, Weitzel NS, Lindley EM, Kleck CJ, , Jameson LC, Patel VV. Preoperative Coagulation Profile Testing to Predict Blood Loss in Complex Spine Surgery: Identifying the Patient at Risk. 15th Annual Meeting of The International Society for the Advancement of Spine Surgery (ISASS). San Diego, California, April 15-17, 2015.
20. Kleck CJ, Perry J, Burger EL, Cain C, Patel VV. Minimally Invasive Technique for Placement of Sacroiliac Arthrodesis Implants using O-Arm and Stealth Navigation. 15 th Annual Meeting of The International Society for the Advancement of Spine Surgery (ISASS). San Diego, California, April 15-17, 2015.
21. Lindley EM, Razavi-Shearer D, Patel VV, Burger EL, Cain CMJ, Finn MA. Medical Marijuana Use Characteristics in Patients With Chronic Spine Pain Disorders. 15 th Annual Meeting of The International Society for the Advancement of Spine Surgery (ISASS). San Diego, California, April 15-17, 2015.
22. Noshchenko A, Lindley EM, Burger EL, Cain CMJ, Patel VV. Rates of Complications and Required Additional Surgical Interventions after Spinal Arthrodesis versus Alternative Treatment in Lumbar Spondylosis: A Systematic Review with Meta Analysis. 15 th Annual Meeting of The International Society for the Advancement of Spine Surgery (ISASS). San Diego, California, April 15-17, 2015.
23. Noshchenko A, Lindley EM, Burger EL, Cain CMJ, Patel VV. Long Term Patient-Centered Clinical Outcomes of Lumbar Arthrodeses in Degenerative Disc Disease: A Systematic Review with Meta Analysis. 15th Annual Meeting of The International Society for the Advancement of Spine Surgery (ISASS). San Diego, California, April 15-17, 2015.
24. Cain C, Hollenbeck JFM, Fattor JA, Patel VV, Burger EL, Laz PJ, Rullkoetter PJ. Patient-specific templating for ADR identifies factors that influence clinical outcomes. 15 th Annual
Meeting of The International Society for the Advancement of Spine Surgery (ISASS). San Diego, California, April 15-17, 2015.
25. Noshchenko A, Lindley EM, Burger EL, Cain CMJ, Patel VV. Rates of Complications and Required Additional Surgical Interventions after Surgical and Nonsurgical Treatment in Lumbar Spondylosis: A Systematic Review with Meta Analysis. Annual Meeting of the International Society of Orthopaedic Surgery and Traumatology (SICOT). Rio de Janeiro, Brazil, November 19-22 2014.
26. Kleck CJ, Illing D, Lindley EM, Cain CMJ, Burger EL, Patel VV. Post-Market Analysis of Pulsed Electromagnetic Field (PEMF) Stimulation Use for Cervical Fusion. Annual Meeting of the International Society of Orthopaedic Surgery and Traumatology (SICOT). Rio de Janeiro, Brazil, November 19-22 2014.
27. Noshchenko A, Lindley EM, Burger EL, Cain CMJ, Patel VV. Long Term Patient-Centered Clinical Outcomes of Lumbar Arthrodeses in Degenerative Disc Disease: A Systematic Review with Meta Analysis. Annual Meeting of the International Society of Orthopaedic Surgery and Traumatology (SICOT). Rio de Janeiro, Brazil, November 19-22 2014.
28. Illing D, Perry J, Lindley EM, Patel VV, Cain CMJ, Kleck CJ, Burger EL. The Effect Of Electronic Medical Record System Implementation On Complication Rates In Adult Spine Deformity Surgery. Annual Meeting of the International Society of Orthopaedic Surgery and Traumatology (SICOT). Rio de Janeiro, Brazil, November 19-22 2014.
29. Noshchenko A, Lindley EM, Burger EL, Cain CMJ, Patel VV. Long Term Patient-Centered Clinical Outcomes of Lumbar Arthrodeses in Degenerative Disc Disease: A Systematic Review with Meta Analysis. 29th Annual Meeting of the North American Spine Society (NASS). San Francisco, California, November 12-15 2014.
30. Burger EL, Illing D, Razavi-Shearer D, Weitzel NS, Lindley EM, Kleck CJ, Cain CMJ, Jameson LC, Patel VV. Preoperative Coagulation Profile Testing to Predict Blood Loss in Complex Spine Surgery: Identifying the Patient at Risk. 29th Annual Meeting of the North American Spine Society (NASS). San Francisco, California, November 12-15 2014.
31. Lindley EM, Razavi-Shearer D, Patel VV, Henry SE, McBeth Z, Burger EL, Cain CMJ, Finn MA. Medical marijuana use characteristics in patients with chronic spine pain disorders. 28th Annual Meeting of the North American Spine Society (NASS). New Orleans, Louisiana, October 9-12 2013.
32. Lindley EM, McBeth ZL, Henry SE, Burger EL, Cain CMJ, Patel VV. Retrograde ejaculation following anterior lumbar spine surgery. 33rd annual Meeting of the International Society of Orthopaedic Surgery and Traumatology (SICOT) & 17th annual meeting of the Pan Arab Orthopaedic Association (PAOA) Orthopaedic World Conference. Dubai, United Arab Emirates, November 28-30 2012.
33. Cain CM, LaFleur M, Rao M, Hollenbeck J, RullkoetterPJ. Pre-op anatomical FEA templating for patient selection and optimizing range of motion in TDR. 19th International Meeting on Advanced Spine Techniques (IMAST). Istanbul, Turkey, July 18-21, 2012.
34. Noshchenko A, Burger EL, Cain CM, Lindley EM, Patel VV. Two Year Bone Morphogenetic Protein Clinical Effects after Lumbar Fusion in Degenerative Disc Disease. 19th International Meeting on Advanced Spine Techniques (IMAST). Istanbul, Turkey, July 18-21, 2012.
35. Cain C, Rao M, Rullkoetter P. Pre-op templating for TDR alignment: Is it clinically relevant? 12th Annual Meeting of The International Society for the Advancement of Spine Surgery (ISASS). Barcelona, Spain, March 20-23, 2012.
PUBLICATIONS/SCHOLARSHIP: Number of original articles in Peer-reviewed journals (Total):
First Author 7Senior Author 4Co-author 29
Book chapters: 5
Online Publications: 1
Doctoral ThesisAssessment of spinal cord blood flow and function in sheep following antero-lateral cervical interbody fusion in animals with and without spinal cord injuries: Thesis for the degree Doctor of Medicine, University of Adelaide, June 1993 (Equivalent to PhD in US)
Book Chapters1. Fagan AB, Cain CMJ, Hall DJ, Fraser RD; Carbon fiber cages for anterior lumbar interbody
fusion: A prospective study. (Book Chapter) Lumbar Segmental Instability; Edited M Szpalski, R Gunzberg, & M Pope, Lippincott Williams & Wilkins, Philadelphia 1999.
2. Christopher MJ Cain. AO Spine manual Principles and Techniques, (Vol 1), Chapter 7.3.1; Modularity of the Universal Spine System, 337-356; Edited M Aebi, V Arlet & J Webb, Thieme New York 2007
3. Christopher MJ Cain. AO Spine manual Principles and Techniques, (Vol 1), Chapter 7.3.3; Universal Spinal Instrumentation for Deformity, 391-422; Edited M Aebi, V Arlet & J Webb, Thieme New York 2007
4. “Spine Surgery Basics”; Christopher MJ Cain. Chapter 1 “Anatomy”, Editors, Patel VV, Patel A, Harrop J, Burger E; Springer-Verlag, Copyright Springer-Verlag Berlin Heidelberg, 2014
5. Christopher J Kleck, Christopher MJ Cain, Evalina L Burger, Vikas V Patel; Thoracolumbar Fractures: Evaluation and Initial Care. Chapmans Orthopedics Chapter 213 – In press
During my residency, I created a comprehensive portfolio of electronic study notes relating to a broad range of orthopedic topics. Having completed my final board certification, I made these notes available to the residents, or registrars as they are referred to in Australia, following me. It is these notes that were subsequently published online in 1997. The content has been updated and added to over the years and are available via open access online.
Peer Reviewed Publications1. McLean AJ, Simpson DA, Cain CMJ, McKaul K, Freund J; Head and Neck Injuries
in Passenger Cars; A review of the literature. Department of Transport and Communications Federal Office for Road Safety, Report CR59, Sept. 1987
2. Cain CMJ, Simpson DA, Fraser RD, McLean AJ, Potter GR, McKaul K; Cervical Spine Injuries in Road Traffic Crashes in South Australia, 1981-86. Aust. N.Z. J. Surg., 1989;56,15-19
3. Cain CMJ, Simpson DA, Ryan GA, Manock CH, James RA; Road Crash Cervical Injuries: A Radiological Study of Fatalities. Am. J. Forensic Med. & Pathol., 1989; 10(3):193-195
4. Howie DW, Cain CMJ, Cornish BL; Pseudo-Abscess of the Psoas Bursa in Failed Double-Cup Arthroplasty of the Hip: J Bone Joint Surg, [B], 1991; 73B:29-32
5. Pohl AP Cain CMJ, Latham JM; Vibrational Resonance Analysis of Bones: Orthopaedic Proceedings Supplement I; J Bone Joint Surg, [B], 1991;73B:5
6. Cain CMJ, Fraser RD; The effect of stabilization of the cervical spine on spinal cord blood flow and function: Orthopaedic Proceedings Supplement II; J Bone Joint Surg, [B], 1991;73B:152
7. Cain CMJ, Langston PG, Weston PF, Fraser RD; Assessment of spinal cord blood flow and function in sheep after antero-lateral cervical interbody fusion in the presence of cord damage: Spine 1994;19(5):511-519
8. Cain CMJ, Fraser RD; Bony and vascular anatomy of the normal cervical spine in the sheep: Spine 1995;20(7):759-765
9. Cain CMJ, Langston PG, Weston PF, Fraser RD; Assessment of spinal cord blood flow and function in sheep following antero-lateral cervical interbody fusion. Neuro Orthopaedics 1995; 17/18:131-141
11. Sanderson PL, Fraser RD, Hall DJ, Cain CMJ, Osti OL, Potter GR; Short segment fixation of thoracolumbar burst fractures without fusion. Eur Spine J 1999;8(6):495-500
13. Freeman B, Fraser RD, Cain CMJ, Hall DJ, Chapple DC; A Randomized, Double-Blind, Controlled Trial: Intradiscal Electrothermal Therapy versus Placebo for the Treatment of Chronic Discogenic Low Back Pain. Spine. 30(21):2369-2377, November 1, 2005
14. Cain CMJ, Schleicher P, Gerlach R, Pflugmacher R, Scholz M, Kandziora F; A New Stand-Alone Anterior Lumbar Interbody Fusion Device: Biomechanical Comparison with Established Fixation Techniques. Spine. 30(23):2631-2636, December 1, 2005.
15. Schleicher P, Gerlach R, Schar B, Cain CMJ, Achatz W, Pflugmacher R, Hass NP, Kandziora F; A Biomechanical Comparison of two different concepts for stand alone anterior lumbar interbody fusion. Eur Spine J. 17(12):1757-1765, December, 2008.
16. Lindley EM, McBeth ZL, Henry SE, Cooley R, Burger EL, Cain CMJ, Patel VV. Retrograde ejaculation following anterior lumbar spine surgery. Spine. 37(20):1785-1789. September 15, 2012
17. Golembeski S, Lindley EM, McBeth ZL, Sophacles A, Burger EL, Cain CMJ, Patel VV. Translating versus non-translating cervical plates. Curr Orth Prac. 2013; 24(2):165-170
18. Noshchenko A; Hoffecker L, Lindley EM, Burger EL, Cain CM, Patel VV.
Perioperative and Long Term Clinical Outcomes for Bone Morphogenetic Protein versus Iliac Crest Bone Graft for Lumbar Fusion in Degenerative Disc Disease. Systematic Review with Meta-analysis. J Spinal Discord Tech. 2014; 27(3):117-35
19. Lindley EM, Levy BJ, Burger EL, Cain CMJ, Patel VV. Failure of the Fernstrom ball in contemporary spine surgery: A case of history repeating itself. Curr Orth Prac. 2014; 25(1):87-91
20. Noshchenko A, Hoffecker L, Lindley EM, Buger EL, Cain CM, Patel VV. Long term treatment effects of lumbar arthrodesis in degenerative disk disease: a systematic review with meta-analysis. J Spinal Disord Tech. 2014 May;27(3):117-35
21. Noshchenko A, Lindley EM, Burger EL, Cain CM, Patel VV. Perioperative and long-term clinical outcomes for bone morphogenic protein versus iliac crest bone graft for lumbar fusion in degenerative disk disease: systematic review with meta-analysis. J Spinal Disord Tech. 2014 May;27(3):117-35
22. Kleck CJ, Cullimore I, LaFleur M, Lindley E, Rentschler ME, Burger EL, Cain CM, Patel VV. A new 3-dimensional method for measuring precision in surgical navigation and methods to optimize navigation accuracy. Eur Spine J. 2016 Jun; 25(6): 1764-1774
23. Noshchenko A, Hoffecker L, Lindley EM, Burger EL, Cain CMJ, Patel VV, Bradford AP. Predictors of spine deformity progression in adolescent idiopathic scoliosis: A systematic review with meta-analysis. World J Orthop. 2015 Aug 18;6(7):537-58
24. Barton C, Noshchenko A, Patel V, Cain C, Kleck C, Burger E. Risk factors for rod fracture after posterior correction of adult spinal deformity with osteotomy: a retrospective case-series: Scoliosis, 2015 Nov 4; 10:30 13013-015 e-Collection
25. Noshchenko A, Lindley EM, Burger EL, Cain CM, Patel VV. What is the Clinical Relevance of Radiographic Non union After Single-Level Lumbar Interbody Arthrodesis in Degenerative Disc Disease?: A Meta-Analysis of the YODA Project Database. Spine. 2016 Jan;41(1):9-17
26. Kleck CJ, MD; Perry JM, Burger EL, Cain CMJ, Milligan K, Patel VV. Sacroiliac Joint Treatment - Personalized to Individual Patient Anatomy Using 3-Dimensional Navigation: Orthopedics March/April 2016 – 39(2): 89-94
27. Fattor JA, Hollenbeck JFM, Laz PJ, Rullkoetter PJ, Burger EL, Patel VV, Cain CMJ: Patient-Specific Templating of Lumbar Total Disk Replacement to Restore Normal Anatomy and Function. Orthopedics March/April 2016 – 39(2): 97-102
28. Kleck CJ, Cullilmore I, LaFleur M, Lindley E, Rentschler ME, Burger EL, Cain CM, Patel VV. A new 3-dimensional method for measuring precision in surgical navigation and methods to optimize navigation accuracy. Eur Spine J. 2016 Jun;25(6):1764-74
29. Zaghloul K, Matoian B, Denardin N, Cain CMJ, Burger EL, Patel VV. Surgical Technique: Preventing Proximal Adjacent Level Kyphosis with Strap Stabilization. Orthopedics. July 2016, 39(4): 794-799
30. Kleck CJ, Illing D, Lindley EM, Noshchenko A, Patel VV, Barton C, Baldini T, Cain CMJ, Evalina L. Burger. Strain in Posterior Instrumentation Resulted in Different Combinations of Posterior and Anterior Devices for Long Spine Fusion Constructs. Spine Deformity. Volume 5, Issue 1, Jan 2017: 27-36
31. Lindley EM, Barton C, Blount T, Burger EL, Cain CM, Seim HB 3rd, Turner AS, Patel VV. An analysis of spine fusion outcomes in sheep pre-clinical models. Eur Spine J. 2017, Jan;26(1):228-239.
32. Noshchenko A, Hoffecker L, Cain CM, Patel VV, Burger EL. Spinopelvic Parameters in Asymptomatic Subjects Without Spine Disease and Deformity: A Systematic Review With Meta-Analysis. Clin Spine Surg. 2017 Mar 31.
33. Barton C, Noshchenko A, Patel V, Cain CMJ, Kleck CJ, Burger EL. Different types of mechanical complications after surgical correction of adult spine deformity with osteotomy. World Journal of Meta-Analysis. Volume 5, Issue 6, Dec 2017: 132-149
34. Justin F.M. Hollenbeck, Christopher M. Cain, Jill A. Fattor, Paul J. Rulkoetter, Peter J. Laz. Statistical shape modeling characterizes three-dimensional shape and alignment variability in the lumbar spine. Journal of Biomechanics. Volume 69, March 1 2018: 146-155
35. Andriy Noshchenko, Christopher MJ Cain, Khaled Zaghloul, Emily Lindley, Christopher Kleck, Evalina L Burger, Vikas Patel. Pedicle screw placement assisted by 3D imaging (O-arm system with Stealth Station software) versus free-hand technique for multilevel posterior thoracolumbar fusion. Current Orthopedic Practice. Volume 29, Number 2, March/April 2018
36. Kleck CJ, Johnson C, Akiyama M, Burger EL, Cain CJ, Patel VV. One-Step Minimally Invasive Pedicle Screw Instrumentation Using O-Arm and Stealth Navigation. Clin Spine Surg. 2018 June; 31(5): 197-202
37. Bozzio AE, Johnson CR, FAttor JA, Kleck CJ, Patel VV, Burger EL, Noshchenko A, Cain CMJ. Stand-alone Anterior Lumbar Interbody, Transforaminal Lumbar Interbody, and Anteior/Posterior Fusion: Analysis of fusion Outcomes and Costs. Orthopedics Sep 2018, 41(5): e655-e662
38. Schroeder N, Noschenko A, Burger E, Patel V, Cain C, Ou-Yang D, Kleck C. Pelvic Incidence Changes Between Flexion and Extension. Spine Deformity 2018 Nov-Dec 6 (6) 753-761
39. Justin FM Hollenbeck, Jill A Fattor, Vikas Patel, Evalina Burger, Paul J Rollkoetter, Christopher MJ Cain. Validation of Pre-operative Templating for Total Disc Replacement Surgery. International Journal of Spine Surgery 2019 Vol 13 (1) 1-8
40. Lindley EM, Perry J, Patel M, Noshchenko A, Bond A, Burger EL, Cain CMJ, Patel VV. Vitamin D hypovitaminosis and efficacy of supplementation in spine surgery patients. Current Orthopedic Practice May/June 2019
41. Rodriguez-Fontan F, Reeves BJ, Noshchenko A, Ou-Yang D, Kleck CJ, Cain C, Evalina Burger-Van der Walt E, Patel VV. Strap stabilization for proximal junctional kyphosis prevention in instrumented posterior spinal fusion. Eur Spine J. 2020, Jan 14, doi: 10.1007/s00586-020-06291-0. [Epub ahead of print]
42. Ayers R, Patel V, Burger E, Cain C, Ou-Yang D, Wessell N, Kleck C. Corrosion of titanium spinal explants is similar to that observed in oil field line pipe steel: Evidence of microbial-influenced corrosion in vivo. Orthopedics Jan 1, 2020, 43(1): 62-67
