SPERMATOGENESISDr SIVARAJ S

DEPT OF PHYSIOLOGYALL INDIA INSTITUTE OF MEDICAL SCIENCES

NEW DELHI

The process by which sperm develop to become mature sperm, capable of fertilizing an ovum

SPERMATOGENESIS

SPERMIOGENESIS

Testis and surrounding structures

Further development of SpermatozoaMobilityCapacitation

Role of Leydig cellsSecreting male sex hormone testosterone

Role of Sertoli cells

Also called Nurse cellsProvides nutrition Blood Testis BarrierSecretes ABP, inhibin, Mullerian inhibiting substance(MIS)

Interrelationships between the hypothalamus, anterior pituitary, and testes

Semen

Volume 1.5- 4.5 mlWhite, opalescent

colourSlightly alkaline pH100-125 million

sperms/ml

Influencing factorsEndocrine environmentTemperature Dietary factors vitamin A,B,ERadiation exposureSmoking, Alcohol Infectious diseases

Summary SpermatogenesisProduce mature spermatocytesProduce haploid gamatesCell proliferationMaintenance of a reserve germ cell

populationSpermatids mature into spermatozoaAcquire motility Capable of fertilizing ovum.

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