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8/10/2019 Spirometry for clinicians by Dr Sarma.ppt
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Visit us at www.drsarma.in
Dr. R.V.S.N.Sarma., M.D., M.Sc.,Consultant Physician & Chest Specialist
E mail: [email protected] 3760 9226 or 2766 0593
93805 21221 or 98940 60593
http://www.drsarma.in/mailto:[email protected]:[email protected]://www.drsarma.in/8/10/2019 Spirometry for clinicians by Dr Sarma.ppt
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Pulmonary Function Tests
Ventilatory Function Spirometry
Clinical Applications
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LUNG FUNCTION TESTS
Tests of Ventilation
Tests of DiffusionTests of PerfusionTests for V-P Mismatch
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LUNG FUNCTION TESTS
Tests of Ventilation
Tests of DiffusionTests of PerfusionTests for V-P Mismatch
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Function of Ventilation
Air Exit Airways, Bronchomotor tone,Secretions, Thoracic muscles etc
Air Entry Expansion of lungs Functioning lung volume, its elasticnature, Lung compliance
Air Out Problem Obstructive Diseases Air In problem Restrictive DiseasesBoth Air Out and In - Combined
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ObjectivesTo detect Obstructive Airway Diseases
To quantify the severity of obstruction.To assess response to IBD.To identify Restrictive Lung Diseases.
To identify flow-volume loop patternsTo understand the clinical relevance.
Spirometry
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PEAK FLOW METER
Diagnosis of ASTHMA or COPD can beconfirmed by demonstrating the presenceof airway obstruction using Spirometry.
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PEFR - Pros and Cons
AdvantagesWith in 1 to 2 minutes,Inexpensive (meter costs less than Rs.1000)Simple, useful for frequent follow up use
Disadvantages Very much effort dependentInsensitive to small changesSmall airways cannot be assessedLarge inter & intra subject variation; accurate
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SPIROMETRY
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SPIROMETRY
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SPIROMETRY
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SPIROMETRY
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Spirometry - Pros and Cons Advantages
Evaluates smaller as well as larger airwaysRelatively easy to use and maintain
Reversibility can be tested with IBD and steroidsDiagnostic as well as management assessments
DisadvantagesCosts about 50,000 + computer and printerTakes time to perform 10 to 15 minutesRequires training at least one day course
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Spirometry ManeuverIn single breath test
A few normal tidal respirationsThen deeeeep inspirationMomentary breath holding
Very forced and fast expiration As hard and as fast as he/she can blow out
Then deep, quick and full inspirationRepeat at least 3 times take the best
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Reproducibility of Spirometry
Adequate explanation to the patientDemonstrating the steps one by one
Encouraging the patient to give best effortTaking at least 3 and usually 5 attemptsSelecting the best effort
Cough and severe dyspnoea may interfereNot like ECG Results depend on effort
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Normal
Flow-Volume
Volume-Time
Test Values
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Spirometry Results
FVC Forced Vital CapacityFEV1 Forced Expiratory Volume
in the first secondFEV1 /FVC Ratio of the above two
PEFR Peak Expiratory Flow RateFET Forced Expiratory Time
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Spirometry Normal Values1. There are no fixed Normal values 2. Dependent on age, sex, height, weight, ethnicity3. Observed value expressed as % of predicted value
FVC Normal if > 80% of predictedFEV1 Normal if > 80% of predicted
FEV1/FVC At least 75%PEFR Normal if > 80% of predictedFET Less than 4 seconds
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The Four Square Game
F E V
1 N O R M A L
F E V 1 < 8 0 %
o f P d
.
FVC NORMALFVC < 80% Pred.
80%
80%
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The Four Square Game
FVC NORMALFVC < 80% Pred.
80%
80%
Normal LungsFEV 1FCV is N
F E V
1 N O R M A L
F E V 1 < 8 0 %
o f P d
.
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The Four Square Game
FVC NORMALFVC < 80% Pred.
80%
80%
F E V
1 N O R M A L
F E V 1 < 8 0 %
o f P d
.
Obstructive DiseaseFEV 1 FCV is Low
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The Four Square Game
FVC NORMALFVC < 80% Pred.
80%
80%
F E V
1 N O R M A L
F E V 1 < 8 0 %
o f P d
.
Restrictive DiseaseFEV 1 FCV is High
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The Four Square Game
F E V
1 N O R M A L
F E V 1 < 8 0 %
o f P d
.
FVC NORMALFVC < 80% Pred.
80%
80%
Combined Obs+ResFEV 1 FCV is N or L
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The Four Square Game
F E V
1 N O R M A L
F E V 1 < 8 0 %
o f P d
.
FVC NORMALFVC < 80% Pred.
80%
80%
Normal LungsFEV 1FCV is N
Obstructive DiseaseFEV 1 FCV is Low
Restrictive DiseaseFEV 1 FCV is High
Combined Obs+ResFEV 1 FCV is N or L
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The Four Square Game
F E V
1 N O R M A L
F E V 1 < 8 0 %
o f P d
.
FVC NORMALFVC < 80% Pred.
80%
80%
Normal AirEntry & Exit
Air Exit Problem Airways choked
Air Entry ProblemLungs expansion
Both Air Entry & Air Exit Problem
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Normal Airways and Lungs
FVC > 80%FEV1 > 80%FEV1 FCV > 75%
PEFR > 80%FET
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Normal Airways - PFT
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Bronchial Asthma Reversible Airway obs.Chronic bronchitis Irreversible with IBD
Emphysema Irreversible with IBDBronchiectasis Airway rigidityCystic Fibrosis
Allergic bronchopulmonary AspergillosisBronchiolitis
Obstructive Airways Disease
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Obstructive Airways Disease
FVC > 80%FEV1 < 80%FEV1 FCV < 75%
PEFR < 80%FET >4 sec
Air Entry Normal Air Exit Problem
FEV1 is LOW
FVC is Normal
FEV1 FVCis < 75%
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Obstructive Airways Disease - PFT
FEV1 is LOW
FVC is Normal
FEV1 FVCis < 75%
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Obstructive V/s Normal
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Obstructive Airways Mild
Bronchial Asthma
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Bronchial Asthma
Reversible Obstruction (IBD)
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Bronchiectasis (Obstructive)
BRONCHOGRAM - BIL UNILATERAL
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Obstructive Airways Severe
Emphysema
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Obstructive Airways Severe -IBD
Emphysema
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Obstructive Lung Diseases
ABPA CYSTIC FIBROSIS
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Upper Airway Obstruction
Truncation of flow loopExpiratory Intra ThoracicInspiratory Extra Thoracic
Both Fixed ObstructionTumourTracheal stenosisTracheal FB
Vocal Chord Dysfunction
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Restrictive Lung Diseases
SarcoidosisTuberculosis (Fibrocaseous)
Interstitial Lung Disease - ILDIdiopathic pulmonary fibrosis - IPFPneumoconiosis
Drug- or radiation-induced lung diseasePneumonectomy
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Extrinsic Restrictive Diseases
Kyphosis, Scoliosis Ankylosing Spondylitis
Massive Pleural effusionPregnancy, Obesity, AscitesRib fractures
Neuromuscular disorders
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Restrictive Lung Disease
FVC < 80%FEV1 > 80%FEV1 FCV > 75%
PEFR > 80%FET
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Restrictive Lung Disease - PFT
FEV1 is LOW
FVC is Normal
FEV1 FVCis < 75%
ILD or IPF
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Restrictive V/s Normal
ILD or IPF
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ILD or IPF
Restrictive Lung Disease - ILD
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Restrictive Lung Disease - ILD
HEPATIOD APPEARANCE
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Restrictive Lung Disease - ILD
RETICULAR PERIPHERIES
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Restrictive Lung Diseases
SARCOIDOSIS RETICULO-NODULAR
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Combined Obstructive + Restrictive
FVC < 80%FEV1 < 80%FEV1 FCV < 75%
PEFR < 80%FET >4 sec
Air Entry Problem Air Exit Problem
FEV1 is LOW
FVC is Normal
FEV1 FVCis < 75%
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Combined Obstructive + Restrictive
FEV1 is LOW
FVC is Normal
FEV1 FVCis < 75%
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Combined Obstructive + Restrictive
KOCHS + EMPHYSEMA
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Other Patterns
FIXEDOBSTRUCTION
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Other Patterns
EXTRA THORACIC
COUGH
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Case 1
Test Pred. Meas. %
FVC 5.5 L 4.5 L 82%
FEV1 4.9 L 3.0 L 61%Ratio 89% 66% -
Man, aged 28, 172cm, 71kg
Non smoker, Cough 3 M
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Case 1
Man, aged 28, 172cm, 71kg
Non smoker, Cough 3 M
Dx : Bron Asthma - Rev
IBD GoodResponse
Test Pred. Meas. %
FVC 5.5 L 4.5 L 82%
FEV1 4.9 L 3.0 L 61%Ratio 89% 66% -
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Case 2
Woman, 48 y, 155cm, 47 kg
Non smoker, Dysp., CP
Test Pred. Meas. %
FVC 3.9 L 2.6 L 66%
FEV1 3.1 L 2.4 L 78%Ratio 79% 92% -
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Case 2
Woman, 48 y, 155cm, 47 kg
Non smoker, Dysp., CP
Diagnosis : # Ribs 5,6,7,8
Test Pred. Meas. %
FVC 3.9 L 2.6 L 66%
FEV1 3.1 L 2.4 L 78%Ratio 79% 92% -
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Case 3
Test Pred. Meas. %
FVC 6.0 L 5.0 L 83%
FEV1 4.8 L 4.1 L 85%Ratio 80% 82% -
Man 35, 175cm, 75kg, MC
Non smoker, Clinical N
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Case 4
Child, 8 y, 128 cm, 19 kg
Stridor, Dysp G3, BS Decr.
Test Pred. Meas. %
FVC 1.9 L 0.7 L 36%
FEV1 1.6 L 0.4 L 25%Ratio 84% 57% -
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Case 4
Child, 8 y, 128 cm, 19 kg
Stridor, Dysp G3, BS Decr.
Test Pred. Meas. %
FVC 1.9 L 0.7 L 36%
FEV1 1.6 L 0.4 L 25%Ratio 84% 57% -
FB in the UAW
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Case 5
Woman, 29 y, 160cm, 41 kg
Had ATT, Dysp G3, Wheeze
Test Pred. Meas. %
FVC 3.5 L 1.8 L 51%
FEV1 2.8 L 1.2 L 43%Ratio 80% 66% -
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Case 5
Diagnosis : TB + ABPA
Test Pred. Meas. %
FVC 3.5 L 1.8 L 51%
FEV1 2.8 L 1.2 L 43%Ratio 80% 66% -
Woman, 29 y, 160cm, 41 kg
Had ATT, Dysp G3, Wheeze
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Case 6
Man, aged 58, 165cm, 51kg
Smoker 16yr, Severe Dysp.
Test Pred. Meas. %
FVC 4.5 L 3.7 L 82%
FEV1 3.6 L 1.8 L 50%Ratio 80% 49% -
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The Four Square Game
F E V
1 N O R M A L
F E V
1 < 8 0 %
o f P d .
FVC NORMALFVC < 80% Pred.
80%
80%
Normal LungsFEV 1FCV is N
Obstructive DiseaseFEV 1 FCV is Low
Restrictive DiseaseFEV 1 FCV is High
Combined Obs+ResFEV 1 FCV is N or L
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Millers Prediction Quadrants
F E V
1 N O R M A L
F E V
1 < 8 0 %
o f P d
.
FVC NORMALFVC < 80% Pred.
Air In and Out NNormal LungsFEV 1FCV is N
Air Exit is chockedObstructive Disease
FEV 1 FCV is Low
Air Entry is reducedRestrictive DiseaseFEV 1 FCV is High
Both Air In & OutCombined Obs+Res
FEV 1 FCV is N or L
90% 100%70% 80%60%
90%
100%
70%
60%
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Take Home Points
All that wheezes is not Asthma only
All Dyspnoea does not wheeze
Do not over simplify dyspnoea to Deriphyllin
Etiology of Dyspnoea needs elucidation
Spirometry tests but Ventilation function only
Need to test diffusion, Perfusion functionsCardiac, Hematologic and other causes
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