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Spirometry for clinicians by Dr Sarma.ppt

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    www.drsarma.in

    Visit us at www.drsarma.in

    Dr. R.V.S.N.Sarma., M.D., M.Sc.,Consultant Physician & Chest Specialist

    E mail: [email protected] 3760 9226 or 2766 0593

    93805 21221 or 98940 60593

    http://www.drsarma.in/mailto:[email protected]:[email protected]://www.drsarma.in/
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    Pulmonary Function Tests

    Ventilatory Function Spirometry

    Clinical Applications

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    LUNG FUNCTION TESTS

    Tests of Ventilation

    Tests of DiffusionTests of PerfusionTests for V-P Mismatch

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    LUNG FUNCTION TESTS

    Tests of Ventilation

    Tests of DiffusionTests of PerfusionTests for V-P Mismatch

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    Function of Ventilation

    Air Exit Airways, Bronchomotor tone,Secretions, Thoracic muscles etc

    Air Entry Expansion of lungs Functioning lung volume, its elasticnature, Lung compliance

    Air Out Problem Obstructive Diseases Air In problem Restrictive DiseasesBoth Air Out and In - Combined

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    ObjectivesTo detect Obstructive Airway Diseases

    To quantify the severity of obstruction.To assess response to IBD.To identify Restrictive Lung Diseases.

    To identify flow-volume loop patternsTo understand the clinical relevance.

    Spirometry

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    PEAK FLOW METER

    Diagnosis of ASTHMA or COPD can beconfirmed by demonstrating the presenceof airway obstruction using Spirometry.

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    PEFR - Pros and Cons

    AdvantagesWith in 1 to 2 minutes,Inexpensive (meter costs less than Rs.1000)Simple, useful for frequent follow up use

    Disadvantages Very much effort dependentInsensitive to small changesSmall airways cannot be assessedLarge inter & intra subject variation; accurate

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    SPIROMETRY

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    SPIROMETRY

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    SPIROMETRY

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    SPIROMETRY

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    Spirometry - Pros and Cons Advantages

    Evaluates smaller as well as larger airwaysRelatively easy to use and maintain

    Reversibility can be tested with IBD and steroidsDiagnostic as well as management assessments

    DisadvantagesCosts about 50,000 + computer and printerTakes time to perform 10 to 15 minutesRequires training at least one day course

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    Spirometry ManeuverIn single breath test

    A few normal tidal respirationsThen deeeeep inspirationMomentary breath holding

    Very forced and fast expiration As hard and as fast as he/she can blow out

    Then deep, quick and full inspirationRepeat at least 3 times take the best

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    Reproducibility of Spirometry

    Adequate explanation to the patientDemonstrating the steps one by one

    Encouraging the patient to give best effortTaking at least 3 and usually 5 attemptsSelecting the best effort

    Cough and severe dyspnoea may interfereNot like ECG Results depend on effort

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    Normal

    Flow-Volume

    Volume-Time

    Test Values

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    Spirometry Results

    FVC Forced Vital CapacityFEV1 Forced Expiratory Volume

    in the first secondFEV1 /FVC Ratio of the above two

    PEFR Peak Expiratory Flow RateFET Forced Expiratory Time

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    Spirometry Normal Values1. There are no fixed Normal values 2. Dependent on age, sex, height, weight, ethnicity3. Observed value expressed as % of predicted value

    FVC Normal if > 80% of predictedFEV1 Normal if > 80% of predicted

    FEV1/FVC At least 75%PEFR Normal if > 80% of predictedFET Less than 4 seconds

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    The Four Square Game

    F E V

    1 N O R M A L

    F E V 1 < 8 0 %

    o f P d

    .

    FVC NORMALFVC < 80% Pred.

    80%

    80%

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    The Four Square Game

    FVC NORMALFVC < 80% Pred.

    80%

    80%

    Normal LungsFEV 1FCV is N

    F E V

    1 N O R M A L

    F E V 1 < 8 0 %

    o f P d

    .

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    The Four Square Game

    FVC NORMALFVC < 80% Pred.

    80%

    80%

    F E V

    1 N O R M A L

    F E V 1 < 8 0 %

    o f P d

    .

    Obstructive DiseaseFEV 1 FCV is Low

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    The Four Square Game

    FVC NORMALFVC < 80% Pred.

    80%

    80%

    F E V

    1 N O R M A L

    F E V 1 < 8 0 %

    o f P d

    .

    Restrictive DiseaseFEV 1 FCV is High

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    The Four Square Game

    F E V

    1 N O R M A L

    F E V 1 < 8 0 %

    o f P d

    .

    FVC NORMALFVC < 80% Pred.

    80%

    80%

    Combined Obs+ResFEV 1 FCV is N or L

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    The Four Square Game

    F E V

    1 N O R M A L

    F E V 1 < 8 0 %

    o f P d

    .

    FVC NORMALFVC < 80% Pred.

    80%

    80%

    Normal LungsFEV 1FCV is N

    Obstructive DiseaseFEV 1 FCV is Low

    Restrictive DiseaseFEV 1 FCV is High

    Combined Obs+ResFEV 1 FCV is N or L

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    The Four Square Game

    F E V

    1 N O R M A L

    F E V 1 < 8 0 %

    o f P d

    .

    FVC NORMALFVC < 80% Pred.

    80%

    80%

    Normal AirEntry & Exit

    Air Exit Problem Airways choked

    Air Entry ProblemLungs expansion

    Both Air Entry & Air Exit Problem

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    Normal Airways and Lungs

    FVC > 80%FEV1 > 80%FEV1 FCV > 75%

    PEFR > 80%FET

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    Normal Airways - PFT

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    Bronchial Asthma Reversible Airway obs.Chronic bronchitis Irreversible with IBD

    Emphysema Irreversible with IBDBronchiectasis Airway rigidityCystic Fibrosis

    Allergic bronchopulmonary AspergillosisBronchiolitis

    Obstructive Airways Disease

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    Obstructive Airways Disease

    FVC > 80%FEV1 < 80%FEV1 FCV < 75%

    PEFR < 80%FET >4 sec

    Air Entry Normal Air Exit Problem

    FEV1 is LOW

    FVC is Normal

    FEV1 FVCis < 75%

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    Obstructive Airways Disease - PFT

    FEV1 is LOW

    FVC is Normal

    FEV1 FVCis < 75%

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    Obstructive V/s Normal

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    Obstructive Airways Mild

    Bronchial Asthma

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    Bronchial Asthma

    Reversible Obstruction (IBD)

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    Bronchiectasis (Obstructive)

    BRONCHOGRAM - BIL UNILATERAL

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    Obstructive Airways Severe

    Emphysema

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    Obstructive Airways Severe -IBD

    Emphysema

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    Obstructive Lung Diseases

    ABPA CYSTIC FIBROSIS

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    Upper Airway Obstruction

    Truncation of flow loopExpiratory Intra ThoracicInspiratory Extra Thoracic

    Both Fixed ObstructionTumourTracheal stenosisTracheal FB

    Vocal Chord Dysfunction

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    Restrictive Lung Diseases

    SarcoidosisTuberculosis (Fibrocaseous)

    Interstitial Lung Disease - ILDIdiopathic pulmonary fibrosis - IPFPneumoconiosis

    Drug- or radiation-induced lung diseasePneumonectomy

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    Extrinsic Restrictive Diseases

    Kyphosis, Scoliosis Ankylosing Spondylitis

    Massive Pleural effusionPregnancy, Obesity, AscitesRib fractures

    Neuromuscular disorders

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    Restrictive Lung Disease

    FVC < 80%FEV1 > 80%FEV1 FCV > 75%

    PEFR > 80%FET

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    Restrictive Lung Disease - PFT

    FEV1 is LOW

    FVC is Normal

    FEV1 FVCis < 75%

    ILD or IPF

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    Restrictive V/s Normal

    ILD or IPF

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    ILD or IPF

    Restrictive Lung Disease - ILD

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    Restrictive Lung Disease - ILD

    HEPATIOD APPEARANCE

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    Restrictive Lung Disease - ILD

    RETICULAR PERIPHERIES

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    Restrictive Lung Diseases

    SARCOIDOSIS RETICULO-NODULAR

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    Combined Obstructive + Restrictive

    FVC < 80%FEV1 < 80%FEV1 FCV < 75%

    PEFR < 80%FET >4 sec

    Air Entry Problem Air Exit Problem

    FEV1 is LOW

    FVC is Normal

    FEV1 FVCis < 75%

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    Combined Obstructive + Restrictive

    FEV1 is LOW

    FVC is Normal

    FEV1 FVCis < 75%

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    Combined Obstructive + Restrictive

    KOCHS + EMPHYSEMA

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    Other Patterns

    FIXEDOBSTRUCTION

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    Other Patterns

    EXTRA THORACIC

    COUGH

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    Case 1

    Test Pred. Meas. %

    FVC 5.5 L 4.5 L 82%

    FEV1 4.9 L 3.0 L 61%Ratio 89% 66% -

    Man, aged 28, 172cm, 71kg

    Non smoker, Cough 3 M

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    Case 1

    Man, aged 28, 172cm, 71kg

    Non smoker, Cough 3 M

    Dx : Bron Asthma - Rev

    IBD GoodResponse

    Test Pred. Meas. %

    FVC 5.5 L 4.5 L 82%

    FEV1 4.9 L 3.0 L 61%Ratio 89% 66% -

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    Case 2

    Woman, 48 y, 155cm, 47 kg

    Non smoker, Dysp., CP

    Test Pred. Meas. %

    FVC 3.9 L 2.6 L 66%

    FEV1 3.1 L 2.4 L 78%Ratio 79% 92% -

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    Case 2

    Woman, 48 y, 155cm, 47 kg

    Non smoker, Dysp., CP

    Diagnosis : # Ribs 5,6,7,8

    Test Pred. Meas. %

    FVC 3.9 L 2.6 L 66%

    FEV1 3.1 L 2.4 L 78%Ratio 79% 92% -

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    Case 3

    Test Pred. Meas. %

    FVC 6.0 L 5.0 L 83%

    FEV1 4.8 L 4.1 L 85%Ratio 80% 82% -

    Man 35, 175cm, 75kg, MC

    Non smoker, Clinical N

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    Case 4

    Child, 8 y, 128 cm, 19 kg

    Stridor, Dysp G3, BS Decr.

    Test Pred. Meas. %

    FVC 1.9 L 0.7 L 36%

    FEV1 1.6 L 0.4 L 25%Ratio 84% 57% -

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    Case 4

    Child, 8 y, 128 cm, 19 kg

    Stridor, Dysp G3, BS Decr.

    Test Pred. Meas. %

    FVC 1.9 L 0.7 L 36%

    FEV1 1.6 L 0.4 L 25%Ratio 84% 57% -

    FB in the UAW

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    Case 5

    Woman, 29 y, 160cm, 41 kg

    Had ATT, Dysp G3, Wheeze

    Test Pred. Meas. %

    FVC 3.5 L 1.8 L 51%

    FEV1 2.8 L 1.2 L 43%Ratio 80% 66% -

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    Case 5

    Diagnosis : TB + ABPA

    Test Pred. Meas. %

    FVC 3.5 L 1.8 L 51%

    FEV1 2.8 L 1.2 L 43%Ratio 80% 66% -

    Woman, 29 y, 160cm, 41 kg

    Had ATT, Dysp G3, Wheeze

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    Case 6

    Man, aged 58, 165cm, 51kg

    Smoker 16yr, Severe Dysp.

    Test Pred. Meas. %

    FVC 4.5 L 3.7 L 82%

    FEV1 3.6 L 1.8 L 50%Ratio 80% 49% -

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    The Four Square Game

    F E V

    1 N O R M A L

    F E V

    1 < 8 0 %

    o f P d .

    FVC NORMALFVC < 80% Pred.

    80%

    80%

    Normal LungsFEV 1FCV is N

    Obstructive DiseaseFEV 1 FCV is Low

    Restrictive DiseaseFEV 1 FCV is High

    Combined Obs+ResFEV 1 FCV is N or L

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    Millers Prediction Quadrants

    F E V

    1 N O R M A L

    F E V

    1 < 8 0 %

    o f P d

    .

    FVC NORMALFVC < 80% Pred.

    Air In and Out NNormal LungsFEV 1FCV is N

    Air Exit is chockedObstructive Disease

    FEV 1 FCV is Low

    Air Entry is reducedRestrictive DiseaseFEV 1 FCV is High

    Both Air In & OutCombined Obs+Res

    FEV 1 FCV is N or L

    90% 100%70% 80%60%

    90%

    100%

    70%

    60%

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    Take Home Points

    All that wheezes is not Asthma only

    All Dyspnoea does not wheeze

    Do not over simplify dyspnoea to Deriphyllin

    Etiology of Dyspnoea needs elucidation

    Spirometry tests but Ventilation function only

    Need to test diffusion, Perfusion functionsCardiac, Hematologic and other causes

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