Supplementary Materials

New complexes with 19-membered pyridine-based macrocycle ligand: Synthesis, characterization, thermal and in vitro anticancer activity

Hanaa A. El-Boraey, Azza A. Serag El-Din, Ibrahim El SayedDepartment of chemistry, Faculty of science, Menoufia University, Shebin El- Kom, Egypt

Journal Name: Thermal analysis and calorimetry

Table 1S: Fundamental IR spectral bands (cm-1)a of the ligand and its metal complexes

No. Compound ν/OH /H2O

ν/NH ν/C=NAzomet-hine

Amide bands ν/M-O ν/M-N Anion/NO3-/OAc-/ClO4

-

I II III IV

L.2H2O 3366/b 3190/b 1604/b 1604/b 1493/sh 1294/sh 757/w - - -

1 [Co(L)(H2O)Cl]Cl.2H2O 3321/w 3190/w 1589/s 1641/sh 1500/s 1296/s 761/m 572/m 530/m -

2 [Co(L)(NO3)2].EtOH 3330/w 3198/sh 1586/sh 1641/sh 1500/s 1301/m 757/m 585/m 526/w [1371/s/1261/sh/1053/w]b

3 [Co(L)(OAc)2].2H2O 3374/b 3190/w 1591/ m 1591/m 1507/m 1296/w 756/m 586/m 471/w [1591/m/1377/w]b

4 [Ni(L)Cl2]½EtOH.1¾H2O 3331/m 3203/b 1587/w 1642/sh 1503/s 1304/m 754/m - 498/w -

5 [Ni(L)(NO3)2].¾EtOH 3328/m 3210/w 1584/s 1642/m 1501/s 1307/m 749/s 593/m 531/m [1372/s/1261/m/1047/s] b

6 [Cu(L)Cl2].7H2O 3333/m 3206/w 1607/b 1607/b 1505/w 1286/w 770/m - 439/sh -

7 [Cu(L)ClO4(H2O)].4H2O 3320/w 3208/w 1615/m 1634/sh 1529/b 1297/sh 758/m 591/sh 432/w [1145/1039/924/647]b

8 [Cu(L)](NO3)2.2H2O 3340/b 3183/b 1619/b 1619/b 1530/m/ 1312/sh 756/w - 430/w [1383/s/756/m] c

9 [Cu(L)OH(OAc)].3H2O 3385/b 3206/b 1594/b 1637/sh 1498/w/ 1295/m 751/m 618/w 553/w [1594/b/1375/m] b

10 [Cu(L)(H2O)3Br]Br.3H2O 3319/b 3190/b 1599/m 1642/sh 1500/w/ 1282/w 770/s 592/w 541/w

11 [Ru(L)Cl2]Cl.4H2O 3301/m 3154/m 1609/s 1646/sh 1509/w/ 1299/m 760/s - 526/s

a s/ strong; sh/shoulder; m/ medium; w/ weak; b/ broad; ν/ stretchingb:monodentate ionc:ionic.

Fig. 1S: 1H NMR spectrum of the ligand

Corresponding author. Tel.: +2- 0111-7532777; Fax: +20 48 2235689.E-mail address: helboraey@yahoomail.com (Hanaa A.El-Boraey).

Fig.2S: Mass spectrum of [Co(L)(H2O)Cl]Cl.2H2O complex 1.

Fig.3S: Mass spectrum of [Co(L)(OAc)2].2H2O complex 3.

m/z

Fig.4S: Mass spectrum of [Ni(L)Cl2]½EtOH.1¾H2O complex 4.

Fig.5S: Mass spectrum of [Cu(L)(H2O)3Br]Br.3H2O complex 10.

Fig.6S: Mass spectrum of [Ru(L)Cl2]Cl.4H2O complex 11.

*Mass of sample (mg)

Fig.7S: TG/DTG curves of complexes 1,3,4,8-10