IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-1
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium tripolyphosphate (STPP) 0 7758-29-4 Henderson C. et al 1959 the toxicity of synthetic detergents and soaps to fish fish sewage and industrial wastes 31: 295-306
sodium tripolyphosphate (STPP) 0 7758-29-4 Maloney T E 1966 Detergent phosphorus effect on algae. algae Journal of water pollutant control fed.38.38-45
sodium tripolyphosphate (STPP) 0 7758-29-4 Sinha P. and Kanamadi R.D. 2000
Effect of Sodium tripolyphosphate (STPP) on the embryonic developmental stages of Zebrafish Brachydanio rerio fish Environment and ecology 18(4): 1007-1010
sodium tripolyphosphate (STPP) 0 7758-29-4 Engelbrecht R S and Morgan J J 1959Studies on the occurrence and degradation of condensed phosphate in surface waters. water Sewage and industrial wastes.31.
sodium tripolyphosphate (STPP) 0 7758-29-4 Zinder B. et al 1984Kinetic studies on the hydrolysis of STPP in sterile solution water water res. 18: 509-512
sodium tripolyphosphate (STPP) 0 7758-29-4
de Madariaga B.M., Ramos M.J. and Tarazona J.V
2007
Risk Assessment on EU phosphate consumption, effects assessment is based on validated field studies.-CEFIC sector group study N/A
Green Plant Research Report GPR-CEEP-07-1-Expanded Final Report. (also Layman's Summary of Report)
sodium tripolyphosphate (STPP) 0 7758-29-4 Inman M.P., Beattie J.K., Jones D.R., and Baldwin D.S. 2001
Abiotic hydrolysis of the detergent builder tripolyphosphate by hydrous manganese dioxide. water Wat. Res. 35,8:1987-1993
sodium tripolyphosphate (STPP) 0 7758-29-4 Lyons JW 1964Sodium Tri(poly)phosphate in the Kaolinite Water System. Clays Journal of Colloid Science 19: 399-412
sodium tripolyphosphate (STPP) 0 7758-29-4 Smith R.S. Et al 1956 effects of synthetic detergents on water coagulation water j am wat wks ass 48: 55-69
sodium tripolyphosphate (STPP) 0 7758-29-4 Sutton A.H 1973The hydrolysis of sodium triphosphate in cod and beef muscle. cod J. Fd Technol., 8: 185-195
sodium tripolyphosphate (STPP) 0De Jager H and Heyns A M
1998Kinetics of acid-catalysed hydrolysis of a polyphosphate in water. N/A J.phys.chem.102.2838-2841.
sodium tripolyphosphate 0Halliwell DJ, Mckelvie ID, Hart BT, Dunhill RH
Hydrolysis of triphosphate from detergents in a rural waste water system N/A Wat. Res. 35(2): 448-454
STPP, 0 7758-29-4 Kulaev AS and Vagabov VM 1983 Polyphosphate metabolism in micro-organisms. n/a Advances in Microbial Physiology, 24: 83-171
STPP, 0 7758-29-4Heppel LA, Harkness DR and Hilmoe RJ 1962
A study of the substrate specificity and othe properties of the alkaline phosphatase of Escherichia coli. E.coli The Journal of Biological Chemistry, 237(3): 841-846
STPP, 0 7758-29-4 Pepin CA and Wood HG 1986Polyphosphate glucokinase from Propionibacterium shermanii bacteria
The Journal of Biological Chemistry, 261(10): 4476-4480
STPP, 0 7758-29-4 Reddy BR 1987
Hydrolytic and enzymatic breakdown of food grade condensed phosphates in white shrimp (Penaeus Setiferus). shrimp Dissertation Abstracts International B47(): 4716
sodium tripolyphosphate (STPP) 0 7758-29-4 Adersen, O. Hagerstrand I., Nordberg G.F. 1982
effect of the chelating agent sodium triphosphate on cadmium toxicity in mice mice environmental research 29, 54-61
sodium tripolyphosphate (STPP) 0 7758-29-4 Andersen O et al 1984 Chelation of cadmium review N/A Environmental Health Perspectives. 54: 249-266
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-2
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium tripolyphosphate (STPP) 0 7758-29-4 Andersen, O., Nielsen, J.B., Svendsen. P. 1988
oral cadmium chloride intoxication in mice: effects of chelation by STPP mice Toxicology, 52: 65-79
sodium tripolyphosphate (STPP) 0 7758-29-4 Bajpai. A., Brahmi Z. 1993
Regulation of Resting and IL-2 activated Human Cytotoxic Lymphocytes by Exogenous Nucleotides: Role of IL-2 and Ecto-ATPases venous blood human cellular immunology 148: 130-143
sodium tripolyphosphate (STPP) 0 7758-29-4 Barica J. et al 1973Mobilization of some metals in water and animal tissues by NTA, EDTA and TPP sediments, crayfish, fish Water res. 7: 1791-1804
Sodium tripolyphosphate (STPP) 0 7758-29-4 Clairiant Hoescht 1975Akute orale toxizitat von natriumtripolyphosphate an mannlichen und weilichen beagle-hunden dog
sodium tripolyphosphate (STPP) 0 7758-29-4 Close M et al 1989
Field evalution of fluorescent whitening agent and sodium triphosphate as indictators of septic tank contamination in domestic wells water
New Zealand journal of marine and freshwater Research:23.563-568
sodium tripolyphosphate (STPP) 0 7758-29-4 Coate W B et al 1978 Respiratory toxicity of enzyme detergent dust Cynomologus Monkeys Toxicology and applied pharmcology 45.471-496.
sodium tripolyphosphate (STPP) 0 7758-29-4 Corbridge D E C 1960The crystal structure of sodium triphosphate, Na5P3O10 phase I. n/a Acta Cryst.13,263.
sodium tripolyphosphate (STPP) 0 7758-29-4 Davies D R and Corbridge D E C 1958The crystal structure of sodium tripolyphosphate, Na5P3O10 phase II. n/a Acta Cryst.11,315.
sodium tripolyphosphate (STPP) 0 7758-29-4 Dymon J J and King A J
1951Structure studies of the two forms of sodium tripolyphosphate. n/a Acta Cryst.4.378
sodium tripolyphosphate (STPP) 0 7758-29-4 Engstrom B et al 1978Effects of detergent formula chelating agents on the metabolism and toxicity of Cadmium in mice. mice Acta pharmacol et toxicol.43.387-397
sodium tripolyphosphate (STPP) 0 7758-29-4 Engstrom B. 1984Effects of chelating agents on oral uptake and renal deposition and excretion of cadmium mice Environmental Health perspective 54: 219-232
sodium tripolyphosphate (STPP) 0 7758-29-4 Engstrom B. 1984 Effects of chelating agents on oral uptake and renal deposition and excretion of cadium. mice Environmental health perspectives.54.219-232.
sodium tripolyphosphate (STPP) 0 7758-29-4 Engstrom B., Nordberg. G.F. 1978Effects of detergent formula chelating agents on the metabolism toxicity of cadmium in mice mice Acta pharmacol. Et toxicol. 43: 387-397
sodium tripolyphosphate (STPP) 0 7758-29-4FDA STPP authorisation 21.182.1810.pdf ? ? ? 21 CFR Ch 1. (4-1-02 Edition), 45
sodium tripolyphosphate (STPP) 0 7758-29-4 Foroutan-Rad M 1981 ?ökologische und toxicologische Betrachtung. Umwelt 3: 218-224
sodium tripolyphosphate (STPP) 0 7758-29-4 Griffith EJ and Metcalf JS 1993 physiochemical properties n/a
The solution properties of supersaturated sodium triphosphate forms I and II. Phosphorus, Sulphur and Silicon. 76:175-178.
sodium tripolyphosphate (STPP) 0 7758-29-4 Griffiths EJ 1975 physiochemical properties n/aThe Chemical and Physical Properties of Condensed Phosphates, 173-200
sodium tripolyphosphate (STPP) 0 7758-29-4 Hsieh F.-M., Huang C., Lin T.-F., Chen Y.-M. and Lin J.-C. 2008
Study of sodium tripolyphosphate-crosslinked chitosan beads entrapped with Pseudomonas putida for phenol degradation. N/A Process Biochemistry. 43:83-92
sodium tripolyphosphate (STPP) 0 13573-18-7 Ishidate M, Sofuni T. 1998 chromosomal aberration test in vitro In vitro Data book of chromosomal aberration test in vitro
sodium tripolyphosphate (STPP) 0 13573-18-7 Ishidate M. et al 1984primary mutagenicity screening of food additives currently used in Japan hamster fibroblasts Fd. Chem. Toxic. 22(8): 623-636
sodium tripolyphosphate (STPP) 0 7758-29-4 Jen C.M.C, Shelef L.A. 1986factors affecting sensitivity of Staphylococcus aureus 196E to polyphosphates bacteria applied and environmental microbiology: 842-846
sodium tripolyphosphate (STPP) 0 7558-29-4 King CS 1944 Manufacture of sodium triphosphates - patent n/a n/a
sodium tripolyphosphate (STPP) 0 7758-29-4 Linke et al 1965 Solubilities Inorganic and Metal-Organic Compounds water
K-Z A Compilation of Solubility Data from the Periodical Literature Volume II 4th Edition. American Chemical Society
sodium tripolyphosphate (STPP) 0 7758-29-4 Lynch RM 2000Modeling of Exposure to Carpet-Cleaning Chemicals Preceding Irritant Induced Asthma in One Patient. Human Environmental Health Perspectives, 108(9): 911-913
sodium tripolyphosphate (STPP) 0 7758-29-4 Matiuchices V.B et al 1984 toxicologic caracterization of STPP rodents Gigiena i Sanitariya 15: 97-101
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-3
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium tripolyphosphate (STPP) 0 7758-29-4 Matyushichev VB et al 1984description of the toxicometric parameters of sodium tripolyphosphate in Saccharomyces cerevisiae yeast Vestnik Leningradskogo Universiteta Biologiya 3: 97-101
sodium tripolyphosphate (STPP) 0 7758-29-4 Nishihata T. et al 1984
possible mechanism behind the adjuvant action of phosphate derivatives on rectal absorption of Cefoxitin in Rats and Dogs dog and rats J. of pharmaceutical Science 73(11): 1523-1525
sodium tripolyphosphate (STPP) 0 7758-29-4 Nixon G A.et al 1990Evaultion of modified methods for determining skin irritation.
Rabbits, Guinea-pigs, humans Regulatory toxicology and pharmacology.12.127-136
sodium tripolyphosphate (STPP) 0 7758-29-4Nixon G.A., Tyson C.A. And Wertz W.C. 1975 Interspecies comparisons of skin Irritancy Rabbits Toxicology and applied pharmacology 31: 481-490
sodium tripolyphosphate (STPP) 0 7758-29-4Nixon G.A., Tyson C.A. And Wertz W.C. 1975 Interspecies comparisons of skin Irritancy guinea pigs Toxicology and applied pharmacology 31: 481-490
sodium tripolyphosphate (STPP) 0 7758-29-4Nixon G.A., Tyson C.A. And Wertz W.C. 1975 Interspecies comparisons of skin Irritancy human Toxicology and applied pharmacology 31: 481-490
sodium tripolyphosphate (STPP) 0 7758-29-4 Ohashi S and Takada S 1961Determination of ortho-, pyro- and tripolyphosphate by the use of a small column of ion-exchange resin N/A
Journal unknown (Department of Chemistry, Kanazawa University), 34(10): 1516-1518
sodium tripolyphosphate (STPP) 0 7758-29-4 Oshiba et al. 1979The effect of tripolyphosphate and phytate on mineral balance in rats Rats sikatsu eisei 23(6): 209
sodium tripolyphosphate (STPP) 0 7758-29-4 Partiridge E P et al. 1941 A thermal microscopic and X-ray study of the system NaPO3-Na4P2O7 n/a .Journal of American chemistry society.454
sodium tripolyphosphate (STTP) 0 7758-29-4 Schaffer JR and Woodhams RT 1977Polyelectrolyte Builders as Detergent Phosphate Replacements N/A Ind Eng Chem Prod Res Dev, 16: 3-11
sodium triphosphate 0 7758-29-4 Schroeder WC et al 1937
Solubility equilibria of sodium sulphate at temperatures from 150°C to 350°C. III. Effect of sodium hydroxide and sodium phosphate. N/A J. Am. Chem. Soc. 59(10): 1783-1790
sodium tripolyphosphate (STPP) 0 Shen CY 1966
) Hydrolytic degradation of sodium tripolyphosphate in concentrated solutions and in presence of foreign ions Ind Eng Chem Prod Res Dev 5: 97-100
sodium tripolyphosphate (STPP) 0 13573-18-7 Shimizu H. et al 1985
The results of microbial mutation test for forty-three industrial chemicals (salmonella and Escherichia coli) bacteria Jpn. J. Ind. Health 27: 400-419
sodium tripolyphosphate (STPP) 0 7758-29-4 Sinton L.W., Finlay R.K and Hannah D.J 1998
Distinguishing human from animal faecal contamination in water: a review. water
New Zealand Journal of Marine and Freshwater Research, 32: 323-348
sodium tripolyphosphate (STPP) 0 7758-29-4 Synder et al 1963 Toxicologic Studies on Brighteners. Toxicology and Applied Pharmacology, 5: 176-18
sodium tripolyphosphate (STPP) 0 7758-29-4 Taylor A. 1980 Soaps and Detergents and the Environment. JAOCS, November 1980: 859A-861A
sodium tripolyphosphate (STPP) 0 7758-29-4 Valsami-Jones E 2004 physiochemical properties n/aPhosphorus in Environmental Technology Principles and
Applications .
sodium tripolyphosphate (STPP) 0 7758-29-4 Van Wazer jr and Campanella D 1950Structure and properties of the condensed phosphates III and IV substance itself J Amer Chem Soc 72: 647 - 663
sodium tripolyphosphate (STPP) 0 7758-29-4 Warne M.J. And Schifko A.D. 1999
Toxicity of laundry detergent components to a freshwater cladoceran and their contribution to detergent toxicity Crustaceans Ecotoxicology and environment safety 44: 196-206
sodium tripolyphosphate (STPP) 0 7758-29-4 Wellman D.M. Et al 2007Efficacy of soluble sodium tripolyphosphate amendments for the in-situ mobilisation of uranium river sediment Environ. Chem. 4: 293-300
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-4
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium tripolyphosphate (STPP) 0 7758-29-4 WHO 1970Toxicological evaluation of some extraction solvents and certain other substances rat, rabbit
FAO Nutrition Meetings Report Series No. 48A. WHO/FOOD ADD/70.39
sodium tripolyphosphate (STPP) 0 7758-29-4 Wieczorek J. et al 1996change in size of casein micelles caused by addition of cleaning agent components casein Netherlands Milk and Dairy J. 50: 53-59
Type 1 detergent with sodium tripolyphosphate 0 7758-29-4 Williams J.B. And Taber D. 1972
Assessing detergent safety: a comparison of a nonphosphate laundry detergent with phosphate detergents Rats J am chem soc 49: 539-551
Type 1 detergent with sodium tripolyphosphate 0 7758-29-4 Williams J.B. And Taber D. 1972
Assessing detergent safety: a comparison of a nonphosphate laundry detergent with phosphate detergents dogs J am chem soc 49: 539-551
Type 1 detergent with sodium tripolyphosphate 0 7758-29-4 Williams J.B. And Taber D. 1972
Assessing detergent safety: a comparison of a nonphosphate laundry detergent with phosphate detergents Rabbits J am chem soc 49: 539-551
Type 1 detergent with sodium tripolyphosphate 0 7758-29-4 Williams J.B. And Taber D. 1972
Assessing detergent safety: a comparison of a nonphosphate laundry detergent with phosphate detergents Rabbits J am chem soc 49: 539-551
Type 1 detergent with sodium tripolyphosphate 0 7758-29-4 Williams J.B. And Taber D. 1972
Assessing detergent safety: a comparison of a nonphosphate laundry detergent with phosphate detergents Rabbits J am chem soc 49: 539-551
Type 1 detergent with sodium tripolyphosphate 0 7758-29-4 Williams J.B. And Taber D. 1972
Assessing detergent safety: a comparison of a nonphosphate laundry detergent with phosphate detergents Monkey J am chem soc 49: 539-551
Type 1 detergent with sodium tripolyphosphate 0 7758-29-4 Williams J.B. And Taber D. 1972
Assessing detergent safety: a comparison of a nonphosphate laundry detergent with phosphate detergents human J am chem soc 49: 539-551
Type 1 detergent with sodium tripolyphosphate 0 7758-29-4 Williams J.B. And Taber D. 1972
Assessing detergent safety: a comparison of a nonphosphate laundry detergent with phosphate detergents human J am chem soc 49: 539-551
Type 1 detergent with sodium tripolyphosphate 0 7758-29-4 Williams J.B. And Taber D. 1972
Assessing detergent safety: a comparison of a nonphosphate laundry detergent with phosphate detergents human J am chem soc 49: 539-551
Type 1 detergent with sodium tripolyphosphate 0 7758-29-4 Williams J.B. And Taber D. 1972
Assessing detergent safety: a comparison of a nonphosphate laundry detergent with phosphate detergents human J am chem soc 49: 539-551
sodium tripolyphosphate (STPP) 0 13573-18-7 Wuembach et al 1966
Research into the toxicity and effects of polyphosphates on growth of cultures of amoeba, rotifers, tadpoles, and on the succession of organisms in cellulose decomposition
Amoeba and rotifer and Amphibian (Bufo bufo and Xenopus laevis)
institut fur Landwirtschaftliche Zoologie und bienenkunde, Report 33 pages
sodium triphosphate 0 7758-29-4 Zettlemoyer AC and Schnieder CH 1956 The hydration of sodium phosphate N/A . J. Am. Chem. Soc. 78(16): 3870-3871
sodium tripolyphosphate 0 Seward RA, Diebel RH, Lindsay RC 1982
Effects of Potassium Sorbate and OtherAntibotulinal Agents on Germination and Outgrowth of Clostridium botulinum Type E Spores in Microcultures bacteria
Applied and evironmental microbiology. 44(5): 1212-1221
sodium tripolyphosphate 0 Steinhauer JE and Banwart GJ 1963The Effect of Food Grade Polyphosphates on the Microbial Population of Chicken Meat bacteria Poultry Science. 43:618-625
disodium orthophosphate 2 munzer DE 1898 ? ?Archiv fur experimentelle Pathologie und Pharmakologie 41: 74-96
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-5
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monosodium phosphate (MSP) 2 7558-80-7 Brusick D 1975
Mutagenic evaluation of compound. FDA 73-2, monosodium phosphate anhydrous powdered, FCC grade
S. typhimuium, Saccharomyces cerevisiae Litton Bionetics Inc. NTIS PB245508
monosodium phosphate (MSP) 2 7558-80-7 Bullock CH and Kamienski FX 1972Initial submission: Primary skin irritation of sodium hexametaphosphate, powdered, in rabbits Rabbits Stauffer Western RC NTIS OTS0555931 (T-1861)
monosodium phosphate (MSP) 2 13472-35-0 Fazekas, IG 1954Enlargement of parathyroid glands by simple acidic compounds rabbits J. Anim. Sci. 80:1690-1695
monosodium phosphate (MSP) 2 7558-80-7 Hitchman A.J. et al 1979 phosphate induced renal calcification in the rat rats can j physiol pharmac 57(1):92
monosodium phosphate (MSP) 2 7558-80-7 House WB and Hogan AG 1955Injury to guinea pigs that follows a high intake of phosphates Guinea pigs The Journal nutrition. 55:507-518
monosodium phosphate (MSP) 2 7558-80-7 Mac Kay E M and Oilver J
1935 Renal damage following the injection of a diet containing an excess of inorganic phosphates.
? Journal of experimental medicine.61
monosodium phosphate 2 7558-80-7 Manowska J and Mazur L 1986Postnatal development of progeny after 5-HT and/or 32P treatment of mice on the first day of gestation. mice Acta Physiologica Hungarica. 67(4): 419-422
monosodium phosphate (MSP) 2 7558-80-7 McFarlane D. 1941 experimental phosphate nephritis in the rat Rats J pathol. Bacteriol. 52: 17
monosodium phosphate (MSP) 2 7558-80-7 Olivier P. and Marzin D. 1987Study of the genotoxic potential of 48 inorganic derivatives with the SOS chromotest bacteria Mutation research, 189(): 263-269
Triple Super Phosphate,. DAP, sodium dihydrogenorthophosphate 2 7558-80-7
Ivy RE, Sulivan TW, Goldner WJ, Graff CR & Peo FR 1972
availability and toxicity of fertiliser phosphates in the rat rat Poultry Science association meeting
monosodium phosphate (MSP) 2 13472-35-0 McMeniman N.P. 1973The toxic effect of some phosphate supplements fed to sheep sheep Australian Veterinarian J. 49: 150-152
monosodium phosphate (MSP) 2 7558-80-7 Sakano K. et al 1995Inorganic phosphate as a negative conditioning factor in plant cell culture plant cells plant science 107: 117-124
monosodium phosphate 2 7558-80-7 N. F. Cymbaluk and G. I. Christison 1989
Effects of dietary energy and phosphorus content on blood chemistry and development of growing horses horse J Anim Sci 1989. 67:951-958.
monosodium phosphate, dicalcium phosphate 2 7758-80-7 Knowlton KF and Herbin JH 2002
Phosphorus Partitioning During Early Lactation in Dairy Cows Fed Diets Varying in Phosphorus Content cows J. Dairy Sci. 85:1227–1236
monosodium phosphate 2 7558-80-7Lopez H, Kanitz FD, Moreria VR, Wiltbank VR and Satter LD 2004
Effect of Dietary Phosphorus on Performance of Lactating Dairy Cows: Milk Production and Cow Health cows J. Dairy Sci. 87:139–146
monosodium phosphate 2 7558-80-7Lopez H, Kanitz FD, Moreria VR, Wiltbank VR and Satter LD 2004
Reproductive Performance of Dairy Cows Fed Two Concentrations of Phosphorus cows Journal of Dairy Science 87(1) 146-157
monosodium phosphate 2 7558-80-7Matsuzaki H, Katsumata S, Uehara M, Suzuki K, Miwa M 2007
High-Phosphorus Diet Induces Osteopontin Expression of Renal tubules in Rats rats (mutant) J. Clin. Biochem. Nutr., 41, 179–183,
monosodium phosphate 2 7558-80-7Wu Z, Satter LD, Blohowiak AJ, Stauffacher RH and Wilson JH 2001
Milk Production, Estimated Phosphorus Excretion,and Bone Characteristics of Dairy Cows Fed Different Amounts of Phosphorus for Two or Three Years cowx J. Dairy Sci. 84:1738–1748
monosodium phosphate 2 7558-80-7wu Z, Tallam S, Ishler VA and Archibald DD 2003
Utilization of Phosphorus in Lactating Cows Fed Varying Amounts of Phosphorus and Forage cow J. Dairy Sci. 86:3300–3308
monosodium phosphate 2 7558-80-7 Wu Z, Satter LD & Sojo R 2000
Milk Production, Reproductive Performance, and Fecal Excretion of Phosphorus by Dairy Cows Fed Three Amounts of Phosphorus cow J Dairy Sci 83:1028–1041
monosodium phosphate (MSP) 2 7558-80-7 Brandao J.C., Bohets H.L., Van De Vyver I.E., Dierickx P.J. 1992
correlation between the in vitro cytotoxicity to cultured fathead minnow fish cells and fish lethality datas for 50 chemicals fish cells (fathead minnow) Chemosphere 25(4):553-562 (558)
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-6
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monosodium phosphate (MSP) 2 7558-80-7 Amlacher E. and Rudolph C. 1981
The thymidine incorporation inhibiting screening system (TSS) to test carcinogenic substances (A nuclear DNA synthesis suppressive short term test) mice Arch. Geschwulst. Forch. 51(7): 605-610
monosodium phosphate (MSP) 2 7558-80-7 Burki et al 1975Influence of NaF and Na2PO3F on chemically induced aberrations in mature sperm of drosophila Drosphilia mutat res, 31: 315-316
monosodium phosphate (MSP) 2 7558-80-7
Ittner J., Dambacher M.A., Muff R., Rüegsegger P., Trechsel U., and Fischer J.A. 1986
Reduced parathyroid hormone response to peroral phosphate in osteoporotic patients. human Mineral Electrolyte Metab. 12:199-203
monosodium phosphate (MSP) 2 7558-80-7 Karbe, K., und G. Jander
1943Die Metaphosphate in KOLLOID-BEIHEFTE. Heft 1-4, p1-146 Heft 1-4, p1-146
monosodium phosphate 2 7558-80-7 Misheva E 1990
Studies of hydroxy-aluminium phosphates obtained from pentahydroxy-dialuminum chloride and monosodium phosphate N/A Arch. Pharm. 323: 447-451
monosodium phosphate (MSP) 2 7558-80-7
Miyoshi K, Funahashi H, Okuda K and Niwa K
1994
Development of rat one-cell embryos in a chemically defined medium: effects of glucose, phosphate and osmolarity. rat (in vitro emvryo) Journal of Reproduction and Fertility. 100:21-26
monosodium phosphate (MSP) 2 7558-80-7 Niemeyer R. and Richter G. 1969
Rapidly labelled polyphosphates and metaphosphates in the Blue-Green Alga Anacystis nidulans algae Arch. Mikrobiol 69: 54-59
monosodium phosphate (MSP) 2 7558-80-7 Stookey G.K. And Muhler J.C. 1965anticariogenic effect in the rat of cereals fortified with a soluble phosphate Rats J. D. Res 45(3): 856-864
monosodium phosphate,calcium phosphate
2 7558-80-7 Unknown ?Handbook of poisoning: prevention, diagnosis and treatment. human Eleventh Edition. Lange Medical Publications.
monosodium phosphate (MSP) 2 7558-80-7
WHO IPCS INCHEM identity purity food additives P-acid & phosphates Tech report 281 dated 1964 1964
Specification for the identity and purity of food additives and their toxicological evaluation: Emulsifiers, stabilizers, bleaching and maturing agents. Who health organisation technical report series No281. guinea pig, rabbit, man WHO
monosodium phosphate (MSP) 2 7558-80-7
Whybro A et al
1998Phosphate supplementation in young men: lack of effect on calcium homeostasis and bone turnover. ? European Journal of Clinical Nutrition, 52: 29-33
monosodium phosphate 2 7558-80-7 Gajatto DS 1939 Ricerche farmicologiche sul fosfato monosodico ? Arch Farmacol Sper. 68:87-98
sodium dihydrogenorthophosphate (MSP) 2 7558-80-7
Agboola HA, Cahill VR, Conrad HR, Ockerman HW, Pareent NA and Plimpton RF 1988
The effects of a high monosodium phosphate and alpha tocopherol supplemented milk replacer diet on veal muscle color and composition. cow Journal of animal science. 66:1676-1685.
sodium dihydrogenorthophosphate 2 7558-80-7 Draper HH, Sie TL and Bergan JG 1972Osteoporosis in Aging Rats Induced by High Phosphorus Diets RAT J Nutr. 102: 1133-1142
monosodium phosphate 2 7558-80-7 Emerick RJ & Embry LB 1964
Effects of calcium and phosphorous levels and diethylstilbestrol on urinary calculi incidence and feedlot performance of lambs Sheep J Anim Sci. 23:1079-1083.
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-7
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monosodium phosphate 2 7558-80-7 Schryver H, Hintz H and Craig P 1971Calcium Metabolism in Ponies Fed aHigh Phosphorus Diet ponies J. NUTRITION,101: 259-264.
disodium phosphate (DSP) 3 7558-79-4 Osser S 1933minimal eventually lethal dose intravenous na2hpo4 acid sodium phosphate Rabbits arch ital sci farmacol 2(5)478-494
disodium phosphate (DSP) 3 7558-79-4 Corbiau L 1936Modifications de la phosphatemie provoquees par l'ingestion journaliere de phosphate bisodique dog CR Soc Biol. 122: 474-475
disodium phosphate (DSP) 3 7558-79-4 Haworth S. et al 1983Salmonella Mutagenicity test results for 250 chemicals (see subst. 216) bacteria environmental mutagenesis supplement 1: 3-142
disodium phosphate (DSP) 3 7558-79-4 Bullock CH and Kamienski FX 1972Initial submission: Primary skin irritation of sodium hexametaphosphate, powdered, in rabbits Rabbits Stauffer Western RC NTIS OTS0555931 (T-1861)
disodium phosphate (DSP) 3 7558-79-4 Erichsen Jones JR
1941A study of the relative toxicity of anions, with polycelis nigra as test animals. polycelis nigra Journal of Experimental Biology. 18: 170-181.
disodium phosphate (DSP) 3 7558-79-4
tsuchiya N, Matsushima S, Takasu N, kypkawa Y and torii M
2004
Glomerular calcification induced by bolus injection with dibasic sodium phosphate solution in Sprague-Dawley rats. rat Toxicologic Pathology. 32:408-412
disodium phosphate (DSP) 3 7558-79-4
Tsuchiya N, Tprii M, Naramara I and Matsui T
2008
Early events involving glomerular calcification induced by dibasic sodium phosphate solution in rats. rat J Toxicol Pathol. 21: 229-237
disodium phosphate (DSP) 3 7558-79-4 Epifanio C.E., Sma R.F. 1975
Toxicity of ammonia, nitrite Ion, Nitrate Ion and orthophosphate to mercenaria mercenaria and crassostrea virginica clam and oyster
institut fur Landwirtschaftliche Zoologie und bienenkunde, Report 33 pages
disodium phosphate (DSP) 3 7558-79-4schonewille JT, Klooster AT & Beynen AC 1993
High phosphorus intake depresses apparent magnesium absorption in pregnant heifers cow J. Anim. Pysiol. a. Anim. Nutr. 71 (1994), 15-21
disodium phosphate 3 7558-79-4 Rodenhutscord M 1996
Response of Rainbow Trout (Oncorhynchus mykiss) Growing from 50 to 200 g to Supplements of Dibasic Sodium Phosphate in a Semipurified Diet fish J. Nutr. 126: 324-331
disodium phosphate (DSP) 3 7558-79-4 Rizzo A.A. 1967
Rabbit corneal irrigation as a model System for studies on the relative toxicity of bacterial products implicated in periodontal disease. The toxicity of neutralised ammonia solutions Rabbits j. periodont 38: 491-499
disodium phosphate (DSP) 3 7558-79-4 Milani R 1946 Induction of mutations with Na3PO4 Drosphilia Drosophila Information Service. 20: 87
disodium phosphate (DSP) 3 7558-79-4 Abelin. I. 1928effects of sodium phosphates and calcium salts on the hormones produced by the thyroid gland rats Biochem. Z.
disodium phosphate (DSP) 3 7558-79-4
Bachrach L., Correa A., Levin R. and Grossman M.
1979
Iron poisoning: Complications of hypertonic phosphate lavage therapy. Brief clinical and laboratory observations. The Journal of Pediatrics. 94,1:147-149
disodium phosphate (DSP) 3 7558-79-4 Buzzati-traverso A 1940-1946
Scientia Genetica. Vol II. Milani R. Produzione di mutazioni letali in Drosophila melaongaster per mezzo di fosfato di sodio Drosphilia N/A
disodium phosphate (DSP) 3 7558-79-4
Report of the scientific committee for food. 7th Series. Commission of the European communities. 1978 N/A N/A N/aA
disodium hydrogenorthophosphate (DSP) 3 7558-79-4
Sobel A, Wexler I, Petrovsky D and Kramer B 1938
Influence of dietary calcium and phosphorous upon action of vitamin D in experimental lead poisoning rat Proc Soc Exper Biol Med. 38: 435
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-8
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
disodium phosphate, zinc phosphide, sodium hypophosphite, calcium hypophosphite 3 7558-79-4 Lecoq R and Villius F 1932
Action de quelques composes inorganiques du phosphore sur l'evolution du rachtisme experimental du rat rat CR Soc Biol. 109:630-631
trisodium phosphate (TSP) 4 7601-54-9 EFSA 2005
Opinion of the scientific panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commision related to treatment of poultry carcasses with chlorine dioxide, acidified sodium chlorite, trisodium phosphate and peroxyacids N/A The EFSA Journal 297.1-28
trisodium phosphate (TSP) 4 7601-54-9 EFSA 2008
Assesment of the possible effect of the four antimicrobial treatment substances on the emergence of antimicrobial resistance N/A EFSA: Summary of opinion
trisodium phosphate (TSP) 4 7601-54-9 European Commission 2003
Opinion onf the Scientific Committee on veterinary measures relating to public health: the evaluation of antimicrobial treatments for poultry carcasses N/A European Commission
trisodium phosphate (TSP) 4 7601-54-9Scientific Committee on Health and Environmental Risks (SCHER) 2008
Environmental impact and effect on antimicrobial resistance of four substances used for the removal of microbial surface contamination of poultry carcasses N/A European Commission
trisodium phosphate (TSP) 4 7601-54-9
Unknown author
1982Workplace environmental exposure level guide: trisodium phosphate.
where applicable, mouse, rabbit, rat
American Industrial Hygiene Association Journal . 43():b51-b52
trisodium phosphate (TSP) 4 7601-54-9 Snider 1993 Can chemicals precipitate dermatitis herpetiformis human J Am Aced Dermatol 28(1): 111-112
trisodium phosphate (TSP) 4 7601-54-9 Ufodike EBC et al 1990Acute toxicity of inorganic fertilizers to African catfish Clarias gariepinus catfish Aquaculture and Fisheries Management, 21: 181-185
trisodium phosphate (TSP) 4 7601-54-9 Fraile A and Sang H 1950Induction of mutation with Na3PO4 and with Harmine Drosphilia Drosophilia Information Service. 24: 81.
trisodium phosphate (TSP) 4 7601-54-9 Arfsten et al 1994
Reversion of bioluminescent bacteria (Mutatox) to their luminescent state upon exposure to organic compounds, munitions, and metal salts bacteria Biomedical and environmental sciences, 7: 144-149
trisodium phosphate (TSP) 4 7601-54-9 Bates J.H. 1967effect of sodium hydroxide and trisodium phosphate on the viability of some unclassified mycobacteria mycobacteria tuberculosis health lab Sci 4(1):42-50
trisodium phosphate (TSP) 4 7601-54-9 Buzzati-Traverso A
1947 Sull'effectto mutageno del fosfato di sodio. ? Ricerca Scientifica E Ricostruzione.17(9-10): 1383-1384
trisodium phosphate (TSP) 4 7601-54-9 Capita R, Alonso-Calleja C, Garcia-Fernandez MC and Moreno B 2001
Influence of strain and trisodium phosphate concentration on growth parameters of Listeria monocytogenes in vitro Bacteria: Listeria Letters in Applied Microbiology. 32: 428-432
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-9
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
trisodium phosphate (TSP) 4 7601-54-9 Capita R, Alonso-Calleja C, Garcia-Fernandez MC and Moreno B 2002
Activity of trisodium phosphate compared with sodium hydroxide was solutions against Listeria monocytogenes attached to chicken skin during refrigerated storage Bacteria: Listeria Food Microbiology . 19: 57-63
trisodium phosphate (TSP) 4 7601-54-9
Capita R, Alsonso-Calleja C, Rodriguez-Perez R, Moreno B and Garcia-Fernandez MC 2002
Influence of Poultry Carcass Skin Sample site on the effectiveness of trisodium phosphate against Listeria monocytogenes Listeria monoctogenes Journal of Food Protection. 65(5): 853-856
trisodium phosphate (TSP) 4 7601-54-9
Capita R, Alsonso-Calleja C, Sierra Castrillo M, Garcia Arias MT, Moreno B and Garcia-Fernandez MC 2000
Sensitivity of Listeria monocytogenes to trisodium fosfate in vitro Listeria monoctogenes Mapfre Medicina. 11(4): 264-273
trisodium phosphate (TSP) 4 7601-54-9 Clark GL and Gross ST 1937Some of the higher hydrates of trisodium phosphate Na3PO4 and trisodium vanadate Na3VO4 N/A Z. Krist. 98:107-111
trisodium phosphate (TSP) 4 7601-54-9 Del Rio E, Capita R, Prieto M & Alonso-Calleja C 2006
Comparison of pathogenic and spoilage bacterial levels on refrigerated poultry parts following treatment with trisodium phosphate Bacteria food Microbiology. 23: 195-198
trisodium phosphate (TSP) 4 7601-54-9 Dickson JS, Nettles Cutter CG, Siragusa GR 1994
Antimicrobial effects of trisodium phosphate against bacteria attached to beef tissue Bacteria Journal of Food Protection. 57(11): 952-955
trisodium phosphate (TSP) 4 7601-54-9 D'Souza DH & Su X ?Efficacy of chemical treatments against murine norovirus, feline calicivirus, and MS2 bacteriophage Viruses Foodborne pathogens and Disease. 1-7
trisodium phosphate (TSP) 4 7601-54-9 Ingerson E. and Morey G.W.
1943preparation and properties of some compounds in the system H2O-Na2O-P2O5 N/A Amer. Min. 28:448-455
trisodium phosphate (TSP) 4 7601-54-9 Kim JW, Slavik MF, Pharr MD, Raben DP, Lobsinger CM and Tsai S 1993
Reduction of Salmonella on post-chill chicken carcasses by trisodium phosphate (Na3PO4) treatment Salmonella Journal of food safety. 14(1): 9-17
trisodium phosphate (TSP) 4 7601-54-9 Mu D, Huang Y, Gates KW and Wu W 1997
Effect of trisodium phosphate on Listeria monocytogenes attached to rainbow trout (oncorhynchus mykiss) and shrimp (Penaeus SPP) during refrigerated storage Bacteria: Listeria Journal of Food Safety. 17(1): 37-46
trisodium phosphate (TSP) 4 7601-54-9 Muus J
1932 Die H.ydrolysegeschwindigheit von Pyrolrhosphorsânre. n/a Physik Chem A, 159, 268-276
trisodium phosphate (TSP) 4 7601-54-9 Phillips CA & Duggan J 2001
The effects of EDTA and trisodium phosphate, alone and in combination with nisin, on the growth of Arcobacter butzleri in culture Bacteria Food Microbiology. 18:547-554
trisodium phosphate (TSP) 4 7601-54-9 Slanvin MF, Kim J, Pharr MD, Raben DP, Tsai S & Lobsinger CM 1994
Effect of trisodium phosphate on Campylobacter attached to post-chill chicken carcasses Bacteria Journal of Food Protection. 57(4): 324-326
trisodium phosphate (TSP) 4 7601-54-9 Somers EB, Schoeni JL, Wong ACL 1994
Effect of trisodium phosphate on biofilm and planktonic cells of Campylobacter jejuni, Escherichia coli O157: H7, Listeria monocytogenes and Salmonella typhimurium Bacteria: various International Journal of Food Microbiology. 22: 269-276
trisodium phosphate (TSP) 4 7601-54-9 Wendrow B & Kobe KA 1952The system sodium oxide - phosphorus pentoxide - water n/a Ind Eng Chem. 4: 1439-1448
trisodium phosphate (TSP) 4 7601-54-9 Yuk H, Marshall DL 2006
Effects of trisodium phosphate adaptation on changes in membrane lipid composition, verotoxin secretion, and acid resistance of Escherichia coli O157:H7 in simulated gastric fluid Bacteria International Journal of Food Microbiology. 106: 39-44
trisodium phosphate (TSP) 4 7601-54-9 Zhuang RY & Beuchat LR 1996Effectiveness of trisodium phosphate for killing Salmonella montevideo on tomatoes Bacteria: Salmonella Letters in Applied Microbiology. 22: 97-100
sodium acid pyrophosphate (SAPP) 5 7758-16-9 Bullock CH and Kamienski FX 1972Initial submission: Primary skin irritation of sodium hexametaphosphate, powdered, in rabbits Rabbits Stauffer Western RC NTIS OTS0555931 (T-1861)
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-10
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium acid pyrophosphate (SAPP) 5 7758-16-9
Craig JM
1957
Histologic and histochemical changes in the kidneys of rats fed a diet with an excess of inorganic phosphate. rat Am J Pathol. 33:
sodium acid pyrophosphate (SAPP) 5 7758-16-9 Sprague J.B. And Logan W.J. 1979Separate and joint toxicity to rainbow trout of substances used in drilling fluids for oil exploration fish Environ. Pollut 79 :269-280
sodium acid pyrophosphate (SAPP) 5 7758-16-9 Jorgenson T.A. Et al 1978ABSTRACT: In vivo mutagenesis investigations of four GRAS chemicals Rats Mutation research, 53: 205
sodium acid pyrophosphate (SAPP) 5 7758-16-9
Gao RC et al
2006Purification and characterization of pyrophosphatase from bighead carp (Aristichthys nobilis). Fish LWT 41: 254-261
sodium acid pyrophosphate (SAPP) 5 7758-16-9Lambert S M, Watters J I
1957The complexes of pyrophosphate ion with alkali metal ions. N/A J Am Chem Soc 79: 4262 - 4265.
sodium acid pyrophosphate (SAPP) 5 7758-16-9 Wagner M.K. And Busta F.F. 1985
Inhibition of Clostridium botulinum 52A Toxicity and Protease Activity by Sodium Acid Pyrophosphate in Media Systems bacteria applied and environmental microbiology July: 16-20
sodium acid pyrophosphate (SAPP) 5 7758-16-9Zhu MJ et al
2004Effect of Maternal Nutrient Restriction in Sheep on the Development of Fetal Skeletal Muscle. Sheep
trisodium pyrophosphate 6 14691-80-6
Marcy JA, Kraft AA, Hotchkiss DK, Molins RA, Olson DG, Walker HW and Merkenich K 1988
Effects of Selected Commercial Phosphate Products on the Natural Bacterial Flora of a Cooked Meat System
bacteria JOURNAL OF FOOD SCIENCE. 53(2): 391-393
Trisodium monohydrogen pyrophosphate 6 14691-80-6 Hubbard FE 1949
Trisodium monohydrogen pyrophosphate and its hydrates N/A Ind Eng Chem 41(12): 2908-2911
Tetrasoidum pyrophosphate (TSPP) 7 7722-88-5 Bailey DE 1976Teratologic evaluation of FDA 73-1 tetrasodium pyrophosphate, anhydrous in mice and rats. mice, Rats NTIS PB245534: Report No: FDABF-GRAS-353
Tetrasoidum pyrophosphate (TSPP) 7 7722-88-5 Brusick D 1975Mutagenic evaluation of compound. FDA 73-1, tetrasodium pyrophosphate
S. typhimuium, Saccharomyces cerevisiae Litton Bionetics Inc. NTIS PB245489
Tetrasoidum pyrophosphate (TSPP) 7 7722-88-5 Mnkeni P.N.S. And MacKenzie A.F. 1987
Effects of added organic residues and calcium carbonate on polyphosphate hydrolysis in four Quebec soils soil Plant and soil 104: 163-167
tetrasodium pyrophosphate 7 7722-88-5Lee RM, Bartami PA, Olson DG & Wiliams FD 1994
Metal Ions Reverse the Inhibitory Effects of Selected Food-Grade Phosphates in Staphylococcus aureus Bacteria
Journal of Food Protection. Vol. 57. No. 4. Pages 284·288.
Tetrasoidum pyrophosphate (TSPP) 7 7722-88-5
Bidwell J.I., Jepson W.B. and Toms G.L.
1970
The interaction of kaolinite with polyphosphate and polyacrylate in aqueous solutions - some preliminary results. N/A Clay Minerals. 8: 445-459
Tetrasoidum pyrophosphate (TSPP) 7 7722-88-5Bonneman-Bémia P.
1941Contribution a l'étude des acides phosphoriques condensés. N/A Ann. Chim. 16:395-477
tetrasodium pyrophosphate (decahydrate) 7 7758-16-9 MacArthur DM and Beevers CA 1957
The crystal structure of sodium pyrophosphate decahydrate, Na4P2O7.10H2O N/A Acta Cryst. 10, 428-432
tetrasodium pyrophosphate (decahydrate) 7 7758-16-9 Rao RVGS and Nampoothiri NS 1955 Unit cell and space group of sodium pyrophosphate N/A Acta cryst. 8:850
Tetrasoidum pyrophosphate (TSPP) 7 7722-88-5 Tono H and Kornberg A 1967Biochemical studies in effects of phosphates in bacterial sporulation. Bacteria Journal of Biological Chemistry: 242(10): 2375-2382
sodium trimetaphosphate (STMP) 8 7785-84-4 Finn SB et al 1978The effect of sodium trimetaphosphate as a chewing gum additive on caries increment in children human j am den assoc 96: 651-655
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-11
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium trimetaphosphate (STMP) 8 7785-84-4 Navia J.M. And Harris R.S. 1969
Longitudinal Study of Cariostatic Effects of Sodium Trimetaphosphate and Sodium Fluoride When Fed Separately and Together in Diets of Rats Rats J. Dent. Res. 48(2): 183-191
sodium trimetaphosphate (STMP) 8 7785-84-4 Navia J.M., Lopez H. And Harris R.S. 1968
Cariostatic effects of sodium trimetaphosphate when fed to rats during different stages of tooth development Rats Archs oral Biol 13: 779-786
sodium trimetaphosphate (STMP) 8 7785-84-4 Bullock CH and Kamienski FX 1972Initial submission: Primary skin irritation of sodium hexametaphosphate, powdered, in rabbits Rabbits Stauffer Western RC NTIS OTS0555931 (T-1861)
sodium trimetaphosphate (STMP) 8 7785-84-4 Busman L.M. And Tabatabai M.A. 1985 Hydrolysis of trimetaphosphate in soils soils soil sci soc amer proc 49: 630-636
sodium trimetaphosphate (STMP) 8 7785-84-4 Katchman BJ and Smith HE
1958 Diffusion of synthetic and natural polyphosphates. n/a Archives of Biochemistry and Biophysics. 75: 396-402.
sodium trimetaphosphate (STMP) 8 7785-84-4 Lieberman I
1956Inorganic triphosphate synthesis by muscle adenylate kinase. n/a J biol chem. 219: 307-317
sodium hexametaphosphate 9 68915-31-1 Abelles. N 1927 toxicity of the (see substance) rats Biochem Z., 163():226
polysodium metaphosphate PSMP 9 10124-56-8 Anderson C.K. Et al 1961
Further observations on the effects of the oral administration of polysodium metaphosphate in the rat Rats Br. J. urol. 33: 135-140
sodium polyphosphate mixture (SPG 69%) 9 68915-31-1 Loessner M.J. Et al 1997
Long-chain polyphosphates inhibit growth of clostridium tyrobutyricum in processed cheese spreads bacteria J. Food protection 60(5): 493-498
sodium polyphosphate 9 68915-31-1 Ortega A. et al 1989Treatment of experimental acute uranium poisoning by chelating agents mice Pharmacology and toxicology 64: 247-251
sodium polyphosphate 9 68915-31-1Maier SK, Scherer S and Loessner MJ 1999
Long-chain polyphosphate causes cell lysis and inhibits Bacillus cereus spetum formation, which is dependant on divalent cations. Bacteria: Bacillus cereus
Applied and environemtal microbiology. 65(9): 3942-3949
sodium polyphosphate 9 68915-31-1 Zaika LL, Scullen J and Fanelli JS 1997
Growth Inhibition of Listeria monocytogenes by Sodium Polyphosphate as Affected by Polyvalent Metal Ions bacteria Journal of food science 62(4): 867-870
sodium hexametaphosphate (SHMP) 10 10124-56-8 Bailey DE 1974Teratologic evaluation of FDA 73-3 sodium hexametaphosphate in mice and rats. mice, Rats NTIS PB245535: Report No: FDABF-GRAS-354
sodium hexametaphosphate (SHMP) 10 10124-56-8 Brusick D 1975Mutagenic evaluation of compound. FDA 73-3, Sodium hexametaphosphate
S. typhimuium, Saccharomyces cerevisiae Litton Bionetics Inc. NTIS PB245486
sodium hexametaphosphate (SHMP) 10 10124-56-8 Bullock CH and Kamienski FX 1972Initial submission: Primary skin irritation of sodium hexametaphosphate, powdered, in rabbits Rabbits Stauffer Western RC NTIS OTS0555931 (T-1861)
sodium hexametaphosphate (SHMP) 10 10124-56-8
Kitahori Y, Konishi N, Cho M, Yamamoto K, Nakagawa Y, Matsui E and Hiasa Y 1998
Lack of carcinogenicity of sodium metaphosphate in Fischer 344 rats. rat J Toxicol Pathol. 11:41-47
sodium hexametaphosphate (SHMP) 10 10124-56-8 Post F.J et al 1963Influence of sodium hexametaphosphate on selected bacteria bacteria appl. Microbiology 11(5): 430-435
sodium hexametaphosphate 10 10125-56-8Matsuoka A, Tsutsumi M & Wantanbe T 1997
Influence of Hexametaphosphate on Staphylococcus aureus Cytoplasmic Membrane Bacteria J. Food Hyg. Soc. Japan. 38(6): 441-445
sodium hexametaphosphate 10 10125-56-8Matsuoka A, Tsutsumi M & Wantanbe T 1995
Inhibitory Effect of Hexametaphosphate on the Growth of Staphylococcus aureus Bacteria J. Food Hyg. Soc. Japan. 36(5): 588-594
sodium hexametaphosphate (SHMP) 10 10124-56-8 Thomson RT 1935 Physical properties of sodium hexametaphosphate. n/a Analyst, 61:320-323
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-12
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium hexametaphosphate (SHMP) 10 10124-56-8Baluyot E S., and Hartford C U
1996Comparsion of polyphosphates analysis by ion chromatography and modified end-griup titration n/a Journal of chromatography A.739.717-222.
sodium hexametaphosphate (SHMP) 10 10124-56-8 Griffith EJ 1967The preparation and properties of tetra-, penta-, hexa-, hepta- and octaphosphates.
Journal of the American chemical society. 89(12): 2884 – 2890
sodium hexametaphosphate (SHMP) 10 10124-56-8 K. K. Jones 1940 The Physiology of Sodium Hexametaphosphate. ? American Water Works Association, p1471-1483
sodium hexametaphosphate (SHMP) 10 10124-56-8
Stover FS et al
1994
Polyphosphate separations and chain length characterization using minibore ion chromatography with conductivity detection. n/a Journal of Chromatography A, 688: 89-95
sodium hexametaphosphate 10 10124-56-8 Weimberg R & Orton WL 1963
Repressible acid phosphomonoesterase and consitutive pyrophosphatase of saccharomyces mellis n/a J. Bacteriol. 86:805-813
sodium metaphosphate insoluble (IMP) 11 10361-03-2 Watanabe M, Sato S and Saito H 1975
The mechanism of the hydrolysis of condensed phosphates. II. The mechanism of the degradation of long-chain polyphosphates N/A Bulletin of the Chemical Society of Japan 48(3): 896-898
sodium metaphosphate insoluble (IMP) 11 10361-03-2 Axmedkahob D.K.A and Xalnaev O.S. 1973MZUZA8 Meditsinskii. Zhurnal Uzbekistana. 8: 90 - 93 ? MZUZA8 Meditsinskii. Zhurnal Uzbekistana. 8: 90 - 93
sodium metaphosphate insoluble (IMP) 11 10361-03-2 Bullock CH and Kamienski FX 1972Initial submission: Primary skin irritation of sodium hexametaphosphate, powdered, in rabbits Rabbits Stauffer Western RC NTIS OTS0555931 (T-1861)
sodium metaphosphate insoluble (IMP) 11 10361-03-2 Irving J.T., Schibler D., and Fleisch H. 1966
Bone formation in normal and vitamin D-treated rachitie rats during the administration of polyphosphates. rat Proc. Soc. Exp. Biol. Med. 123:332-335
sodium metaphosphate insoluble (IMP) 11 10361-03-2Katchman BJ and Van Wazar JR
1954The "soluble" and "insoluble" polyphosphates of yeast. yeast Biochi biophys Acta. 14: 445-446
sodium metaphosphate insoluble (IMP) 11 10361-03-2 Szymona M, Szymona O and Kulesza S 1962On the occurance of inorganic polyphosphate hexokinase in some microorganisms. n/a Acta Microbiologica Polonica. 11:287-300
sodium metaphosphate insoluble (IMP) 11 10361-03-2 Van Wazer J R, Campanella D A 1950
Structure and properties of the condensed phosphates. IV. Complex ion formation in polyphosphate solutions. N/A J Amer. Chem. Soc. 72: 655 - 663
potassium dihydrogenorthophosphate 12 7778-77-0 Sakamoto S. amd Yone Y. 1979
availability of phosphorus compounds as dietary phosphorus sources for red sea bream (chrysophrys major) fish J. Fac. Agr. Kyushu Univ. 23, 177-184
monopotassium phosphate (MKP) 12 7778-77-0 Bailey DE 1975Teratologic evaluation of FDA 73-65 monopotassium phosphate in mice and rats. mice, Rats NTIS PB245521: Report No: FDABF-GRAS-340
monopotassium phosphate (MKP) 12 7778-77-0 Kamienski FX 1971
NTIS Initial Submission: Toxicology Lab Report T-1680 Regarding Toxicity Studies Including Tripotassium Phosphate and Other Chemicals with Cover Letter Dated 102729 Monopotassium Phosphate Acute Oral Screen Male Rats Stauffer Chemical Company, Western Research
monopotassium phosphate (MKP) 12 7778-77-0 Brusick D 1975Mutagenic evaluation of compound. FDA 73-65, monopotassium phosphate granular food grade
S. typhimuium, Saccharomyces cerevisiae Litton Bionetics Inc. NTIS PB245513
monopotassium phosphate (MKP) 12 7778-77-0 Fischer W et al 1991
Molluscicidal activity of potassium to the zebra mussel, Dreissena polymorphia; toxicity and mode of action Mussel Aquatic toxicology 20(4): 219-234
monopotassium phosphate 12 7778-77-0Brown ML Jaramilloe F Jnr, Gatlin DM III 1993
Dietary phosphorus requirements of juvienille sunshine bass, Morone chrysops ♀ X M. saxatilis ♂ fish Aquaculture, 113 (1993) 355-363
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-13
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monopotassium phosphate 12 7778-77-0Dougall DS, Curry Woods L III, Douglass LW & Soares JH 1996
Dietary Phosphorus Requirement of Juvenile Striped Bass Morone saxatillis fish
The Journal of the world aquaculture society. 27(1): 82-92
monopotassium phosphate (MKP) 12 7778-77-0
Béranger-Yvon A.et al.
1958
Quelques aspects de l'action des acides orthophorique, pyrophosphorique et adénosine-triphosphorique sur la croissance et la photosynthèse de chlorella pyrenoidosa chick. algae
Revue de Cytologie et de Biologie Végétales. XIX,2:433-452
potassium dihydrogen phosphate 12 7778-77-0 Biggers JD and McGinnis LK 2001Evidence that glucose is not always an inhibitor of mouse preimplantation development in vitro mouse Human Reproduction. 16(1): 153-163
monopotassium phosphate (MKP) 12 7778-77-0 Frazer BC and Pepinsky R 1953X-ray analysis of the ferroelectric transition in KH2PO4 N/A Acta Cryst. 6:273
monopotassium phosphate (MKP) 12 7778-77-0Harris W W, et al.
1976Stimulation of Bone Formation in vivo by Phosphate Supplementation, dogs Calcif., Tiss. Res., 22, 85-98.
monopotassium phosphate (MKP) 12 7778-77-0Petters RM. et al.
1990Glucose, glutamine and inorganic phosphate in early development of the pig embryo in vitro. pig Journal of Reproduction and Fertility. 89:269-275
Dipotassium phosphate (DKP) 12 7778-77-0 Rana 1974 Ecophysiological studies on the uptake of the pollutants, copper, zinc and phosphate by certain algaealgae Indian J Ecol 1(1): 1-11
monopotassium phosphate (MKP) 12 7778-77-0 Ubbelohde AR & Woodward I 1947
Structure andthermal properties associated with some hydrogen bonds in crystals. VII. Behaviour of KH2PO4 and KH2AsO4 on cooling n/a Proceedings of the Royal Society 188 S: 358-372
monopotassium phosphate (MKP) 12 7778-77-0 West J 1930XXVI. A quantitative X-ray analysis of the structure of potassium dihydrogen phosphate (KH2PO4) n/a Zeitschrift Fur Kristallographie. 74:306-332
Dipotassium phosphate (DKP) 13 7758--11-4 Bullock CH and Kamienski FX 1972Initial submission: Primary skin irritation of sodium hexametaphosphate, powdered, in rabbits Rabbits Stauffer Western RC NTIS OTS0555931 (T-1861)
Dipotassium phosphate (DKP) 13 7758-11-4
Chu, SP
1943
The influence of the mineral composition of the medium on the growth of planktonic algae. Part II: The influence of the concentration of inorganic nitrogen and phosphate phosphorus. algae Journal of Ecology, 31(2):109-148.
Dipotassium phosphate (DKP) 13 77 Schneider P. et al - Part I 1980
Potassium Hydrogen Phopshate induced nephropathy in the dog. Part I. Pathogenesis of tubular atrophy dog Vet. Pathol. 17: 699-719
Dipotassium phosphate (DKP) 13 7758-11-4 Schneider P. et al - Part II 1980
Potassium Hydrogen Phopshate induced nephropathy in the dog. Part II. Glomerular alterations dog Vet. Pathol. 17: 720-737
dipotassium phosphate 13 7758-11-4Elam CJ, Schneider BH and Ham WE 1956 Experimetally produced urinary canuli in sheep Sheep J Anim Sci 1956. 15:800-810.
Dipotassium phosphate (DKP) 13 7758-11-4 Flatt R, Brunisholz G and Bourgeois J 1956Contribution a l'étude du systéme quinaire. Ca++ - K+-H+-NO3- - PO4--- -H2O N/A Helv Chim Acta. 39:841-53
Dipotassium phosphate (DKP) 13 7758-11-4 Nowotarski JS and Bird HR 1943Dietary calcium and phosphorus levels and the vitamin D requirement of the Chick chicken Poultry Sci. 22:72-78
Dipotassium phosphate (DKP) 13 7758-11-4 Selva L 1947 Le system binaire: eau phosphate dipotassique n/a Bull. Soc. Chim. France: 261-264
tetrapotassium pyrophosphate (TKPP) 15 7320-34-5 Racz G.J. And Savant N.K. 1972Pyrophosphate Hydrolysis in soil as influenced by flooding and fixation soil soil sci soc amer proc 36: 678-682
tetrapotassium pyrophosphate (TKPP) 15 7320-34-5 Shimoji N. et al 1988
Subchronic oral toxicity study of potassium phosphate as a preliminary to long-term carcinogenicity studies in F344 rats Rats Bul. Institute Hygenic sciences 106: 66
Potassium pyrophosphate, polyphosphates and cyclophosphates 15 7320-34-5 Kulaev IS 2004 The biochemistry of Inorganic polyphosphates N/A 2nd edition John Wiley and Sons Ltd
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-14
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
potassium tripolyphosphate (KTPP) 16 13845-36-8Lyutsko VA, Shashkova IL and Prodan EA 1982
Vibrational spectra of hydrated acid and intermediate potassium tripolyphosphate N/A Source unknown
potassium metaphosphate (KMP) 17 7790-53-6 Gassner K. 1957experiments on the metabolic behaviour of highly condensed potassium metaphosphate Rats biochem Z., 328: 485-491
potassium metaphosphate (KMP) 17 7790-53-6 Thilo E. and Wieker W. 1957the hydrolysis of condensated phosphates in aqueous solution water Z anorg allg chem 291: 164-185
monoammonium phosphate (MAP) 18 7722-76-1 Brosheer JC and Anderson JF 1946 The system ammonia-phosphoric acid-water at 75° N/A unknown, 68:902-904
Fire retardant (Phos-Chek)containing Monoammonium phosphate 18 7722-76-1 Buscemi DM 1998
The effects of fire control chemicals on hatchability of northern bobwhite quail (Colinus virginianus) and red-winged blackbirds (Agelaius phoniceus) Birds University of Virginia MS Thesis.
diammonium phosphate (DAP) 18 7722-76-1 Creamer FL and Fox RH 1980
The toxicity of banded Urea or Diammonium phosphate to corn as influenced by soil temperature, moisture and pH SOIL Soil Sci Soc Am J. 44(2): 296
monoammonium phosphate (MAP) 18 7722-76-1 Day HG and Stein HJ 1938
The effect upon hematopoeisis of variations in the dietary levels of Calcium, Phosphorous, Iron and Vitamin D: Two figures. Rats The Journal of Nutrition 16(6): 525-540
monoammonium phosphate (MAP) 18 7722-76-1 Polosin VA and Shakhporonov MI 1947 ? N/A Zh Fiz Khim. 21:119-123monoammonium phosphate (MAP) 18 7722-76-1 Singer R.H. and McCarty R.T. 1971 Acute Ammonium Salt Poisoning in Sheep. sheep Am. J. Vet. Res., 32(8): 1229-1238
diammonium phosphate (DAP) 18 7722-76-1 Singh R et al 1995 Biochemical toxicity of fertiliser di-ammonium phosphate to fish Clarias batrachus FISH Uttar Pradesh J Zool. 15(2): 144-148
monoammonium phosphate (MAP) 18 7722-76-1 Tenzer L, Frazer BC, Pepinsky R 1958 A neutral structure analysis of tetragonal NH4H2PO4 N/A Acta Cryst. 11:505
monoamminium phosphate 18
Williams SN, McDowell LR, Warnick AC, Wilkinson NS and Lawrence LA 1991
Phosphorus concentrations in blood, milk, feces, bone and selected fluids and tissues of growing heifers as affected by dietary phosphorus cows
Livestock Research fro Rural development. 3(2) [no pg numbers]
Phos-chek (DAP + additives) Fire-Trol 931 (ammonium polyphosphate + additives) 19 7783-28-0 Johnson WW and Finley MT 1980
Handbook of Acute Toxicity of Chemicals to Fish and Aquatic Invertebrates. Fish and invertebrates
United States Department of the Interior Fish and Wildlife Service / Resource publication 137.
diammonium phosphate (DAP) 19 7783-28-0
Palanichamcy S., Arunachamy S and Balasubramanian M PFood consumption of Sarotherodon Mossambicus (Trewaves) exposed to sublethal concentration of diammonium phosphate 1985
Food consumption of Sarotherodon Mossambicus (Trewaves) exposed to sublethal concentration of diammonium phosphate fish ?
diammonium phosphate (DAP) 19 7783-28-0Singh HR, Anoop K, Dobriyal and Pokhriyal RC 1985
Toxicty of Diammonium Phosphate to the Hillstream Minor Carp Barilus Bendelisis Fish Uttar Pradesh J Zool, 5(1): 89-93
diammonium phosphate (DAP) 19 7783-28-0 Smith JP, Lehr JR and Brown WE 1957Crystallographic properties of diammonium phosphate, (NH4)2HPO4 N/A Acta Cryst. 10: 709
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-15
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
diammonium phosphate (DAP) 19 7783-28-0
Stavanja MS, Curtin GM, Ayres PH, Bombick ER, Borgerding MF, Morgan WT, Garner CD, Pence DH and Swauger JE
2008Safety assessment of diammonium phosphate and urea used in the manufacture of cigarettes. CHO cells Experimental and Toxicologic Pathology 59: 339-353.
diammonium phosphate (DAP) 19 7783-38-0 Wood 1985 Marine bioassays with lobster larvae and gammaridsLobster larvae and Gammarids Can Tech Rep Fish Aquat Sci, 0: 351-372
diammonium phosphate (DAP) 19 7783-28-0 Yadav HN and Akela BP 1997Effect of DAP toxicity on haematology of catfish Heteropneustes fossilis (Bloch). Fish Environment and Ecology 15(2): 455-459
diammonium phosphate (DAP) 19 7783-28-0 Yadav HN, Akela BP and Kumari A 1998Effect of DAP toxicity on certain haematological parameters of Heteropneustes fossilis (Bloch). Fish Environment and Ecology 16(2): 431-434
diammonium phosphate (DAP) 19 7783-28-0Oltjen RR, Waller GR, Nelson AB and Tillman AD 1963
Ruminant studies with diammonium phosphate and urea Sheep J. Anim. Sci. 24:36-42
diammonium phosphate (DAP) 19 7783-28-0Schaadt H, Johnson RR and McClure KE 1966
Adaptation to and platability of urea, biuret and diammonium phosphate as NPN sources for ruminants Sheep J. Anim. Sci. 23: 73-77
diammonium phosphate (DAP) 19 7783-28-0 Johnson RR and McClure KE 1964
In vitro and in vivo comparisons of the utilization of urea, biuret and diammonium phosphate by sheep. Sheep J. Anim. Sci. 23: 208-213
diammonium phosphate (DAP) 19 7783-28-0 Russel EL, Hale WH and Hubbert F 1962Evaluation of diammonium phosphate as a source of nitrogen for ruminants Sheep J. Anim. Sci. 21: 523-226
diammonium phosphate (DAP) 19 7783-28-0 Cowman GL and Thomas O 1962diammonium phosphate as a source of nitrogen and phosphorous for beef cattle Cows J. Anim. Sci. 21: 992
diammonium phosphate 19Lassiter CA, Brown LD and Keyser D 1962
An evaluation of diammonium phosphate as a nitrogen source for ruminants cows Mich State University Quartly Bulletin.
ammonium polyphosphates 20 14728-39-3 Aoyama M. 1975 Effect of anti-flame treating agents on the skin rats and rabbits Nagoya Med, 20(1): 11-19
Ammonium polyphosphate (APP) 20 68333-79-9 Bell et al 1986Ammonium Polyphosphate as a source of nitrogen and phosphorous in cattle rations catlle Agricultural experimental station bulletin 497: 1-15
ammonium polyphosphate 20 14728-39-3 McBeath et al 2006Hydrolysis of Pyrophosphate in a Highly Calcareous Soil: A Solid-State Phosphorus-31 NMR Study soil soil sci soc amer proc, on line march 29
Ammonium polyphosphate (APP) 20 68333-79-9 Metzger RJ 1980Liquid ammonium polyphosphate as a fish pond fertilizer FISH
Transactions of the American Fisheries Society, 109: 563-570
Liquid ammonium polyphosphate (APP) 20 68333-79-9 Metzger RJ and Boyd CE 1980Liquid ammonium polyphosphate as a fish pond fertiliser. Fish
Transactions of the American Fisheries society. 109:563-570
Liquid ammonium polyphosphate 20 68333-79-9 Metzger RJ and Boyd CE 1980Liquid ammonium polyphosphate as a fish pond fertiliser. fish and plankton
Transactions of the American Fisheries society. 109:563-570
ammonium polyphosphate, triammonium pyrophosphate 20 14728-39-3 Sample E.C. Et al 1979
reactions of ammonium ortho- and polyphosphate fertilizer in soil: III effects of associated cations soil soil sci soc amer 43: 58-65
ammonium polyphosphate 20 14728-39-3 Venugopalan M.V. And Prasad R. 1989Hydrolysis of ammonium polyphosphate in soils under aerobic and anaerobic conditions soils biol fertil soils 8: 325-327
monocalcium phosphate (MCP) 21 7758-23-8 Sorenson SS 1985
Initial Submission: acute toxicity test battery for monocalcium phosphate anhydrous with cover letter dated 102392 Rat NTIS OTS0571950 Report No. T-12163
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-16
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monocalcium phosphate (MCP) 21 7758-23-8 Sorenson SS 1985
Initial Submission: acute toxicity test battery for monocalcium phosphate anhydrous with cover letter dated 102392 Rabbit NTIS OTS0571950 Report No. T-12163
monocalcium phosphate (MCP) 21 7758-23-8 Sorenson SS 1985
Initial Submission: acute toxicity test battery for monocalcium phosphate anhydrous with cover letter dated 102392 Rabbit NTIS OTS0571950 Report No. T-12163
monocalcium phosphate (MCP) 21 7758-23-8 Sorenson SS 1985
Initial Submission: acute toxicity test battery for monocalcium phosphate anhydrous with cover letter dated 102392 Rabbit NTIS OTS0571950 Report No. T-12163
monocalcium phosphate (MCP) 21 7758-23-8 Brusick D 1975Mutagenic evaluation of compound. FDA 71-81, monocalcium phosphate
S. typhimuium, Saccharomyces cerevisiae Litton Bionetics Inc. NTIS PB245509
monocalcium phosphate (MCP) 21 7758-23-8 Guillaume M. 1963Hydrolysis of primary calcium phosphate in function of the temperature water Bull. Sco. Roy. Sci. Liege 32(5-6): 362-365
monocalcium phosphate (MCP) 21 7758-23-8 Hitchman A.J. et al 1979 phosphate induced renal calcification in the rat rats can j physiol pharmac 57(1):92
monocalcium phosphate (MCP). 1-hydrate 21 10031-30-8 Misra N.P. Et al 1981
interaction of monocalcium phosphate monohydrate with water solubility and hydrolysis soil fert news 26: 34-36
monocalcium phosphate (MCP) 21 7758-23-8 Pozin M.E. Et al 1959the hydrolysis rate of monocalcium phosphate in aqueous solutions water j appl chem ussr 32: 736
monocalcium phosphate (MCP) 21 7758-23-8 Sollmann T. Schettler O.H. And Wetzel N.C. 1921 studies of chronic toxicity in albino rats IV Rats j pharm exp therap 17():197-225
monocalcium phosphate (MCP) 21 7758-23-8 Brown WE and Lehr JR 1959Application of phase rule to the chemical behaviour of monocalcium phosphate monohydrate in soils. N/A Soil Sci. Soc. Am. Proc. 23:7-11
monocalcium phosphate (MCP) 21 7758-23-8 Lindsay WL and Stephenson HF 1959
Nature of reactions of monocalcium phosphate monohydrate in soils: I. The solution that reacts with the soil. N/A ?
monocalcium phosphate (MCP) 21 7758-23-8Jones MR, Hardwick LL, Clemens RA 1987
Effect of calcium phosphate supplementation on blood pressure in the wistar rat. rat Nutrition Research, 7:779-785
monocalcium phosphate 21 7758-23-8 Roy PK and Lall SP 2003dietary phosphorus requirements of juvienile haddock (Melanogrammus aeglefinus L.) fish Aquaculture 221 (2003) 451–468
monocalcium phosphate. Monohydrate 21 7758-23-8 Vielma J and Lall SP 1998
Control of phosphorus homeostasis of Atlantic salmon (Salmo salar) in fresh water. fish Fish Pysiology and biochemistry, 19 :83-93
monocalcium phosphate (MCP) 21 7758-23-8
In Russian, so the russians :)
1987
GTPZAB (1987) Phosphoric Acid calcium salt (2:) monohydrate. RTECS Gigiena Truda I Professional'nye Zabolevniya. N/A Labor Higiene and Occupational Diseases 31 (12) 53.
monocalcium phosphate (MCP) 21 7758-23-8 Alfonso et al 1988Comunicacion Corta Intoxicacian por fosfato dicaclcico (CaHPO4) en terneros calf Rev Salud Anim, 10 : 261-262
monocalcium phosphate (MCP) 21 7758-23-8 Behling et al 1988
Mineral metabolism of aging female rats fed various commercially available calcium supplements or yoghurt rats Pharmaceutical Research, 5 (8): 501-505
monocalcium phosphate (MCP) 21 7758-23-8 Belopolski et al 1940The vapour pressures of saturation solutions and solubilities in the system N/A Unknown
monocalcium phosphate (hydrated and anhydrous), 21 7758-23-8 Bjerrum N 1949
Investigations on the solubility of calcium phosphates N/A Niels Bjerrum Selected Papers. 245-249
monocalcium phosphate (MCP) 21 7758-23-8 Cohen S.M. Et al 2000Calcium phosphate containing precipitate and the carcinogenicity of sodium salts in rats rats Carcinogenesis 21(4): 783-792
monocalcium phosphate (MCP) 21 7758-23-8 Cohen SM 1998 Cell proliferation and carcinogenesis Cells drug metabolism reviews, 30(2): 339-357
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-17
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monocalcium phosphate (MCP) 21 7758-23-8 Daabees N et al 1988Dissolution behaviour of carbonated apatites in the presence of some ions
drug development and industrial pharmacy, 14(3): 1855-1875
monocalcium phosphate (MCP) 21 7758-23-8
Everson GE et al
1988Chemistry Set Chemicals: An Evaluation of Their Toxic Potential. N/A Vet Hum Toxicol 30(6): 589-592
monocalcium phosphate (MCP) 21 7758-23-8
Fleisch H and Russell RGG
1972
A Review of the Physiological and Pharmacological Effects of Pyrophosphate and Diphosphonates on Bones and Teeth. N/A J Dent Res Supplement to No 2, 51:324-332
monocalcium phosphate (MCP) 21 7758-23-8 Gigiena I Sanitaria, 52 (12):87, 1987 1987 ? Gigiena I Sanitaria, 52 (12):87, 1987
monocalcium phosphate dihydrate (MCP) 21 7758-23-8 Knox D, Cowey CB and Adron JW 1981
Studies on the nutrition of salmoid fish. The magnesium requirements of rainbow trout (Salmo gairdneri) fish Br. J. Nutr:45
monocalcium phosphate (MCP) 21 7758-23-8Larson H W E
1935Preparation and properties of mono-, di- and tricalcium phosphates. N/A Industrial and engineering chemistry.7
monocalcium phosphate (MCP) 21 7758-23-8 Lehr JR, Brown WE and Brown EH 1959Chemical behaviour of monocalcium phosphate monohydrate in soils. Soil Sci. Soc. Am. Proc. 23: 3-12
Calcium phosphate dust 21 7758-23-8 Miller JW 1936The physiological response of peritoneal tissue to certain industrial and pure mineral dusts guinea pig Public health reports. 51(49):1677-1688
monocalcium phosphate (MCP) 21 7758-23-8 Rodehutscord M et al 2003
Response of growing Pekin ducks to supplementation of monobasic calcium phosphate to low phosphorus diets duck Poult. Sci. 82(2):309-319.
monocalcium phosphate (MCP) 21 7758-23-8 Rodehutscord M et al 2005
Comparative studies with three-week-old chickens, turkeys, ducks and quails on the response in phosphorus utilization to a supplementation of monobasic calcium phosphate turkey, duck Poult. Sci. 82(2):309-319.
monocalcium phosphate (MCP) 21 7758-23-8 Taylor AW and Gurney EL 1965the effects of salts on the dissolution of monocalcium phosphate Soil Sci Soc Am J. 29:151-153
monocalcium phosphate (MCP) 21 7758-23-8 Yakovleva, Efimova, Shafranskii 1979dihydromoncalcium phosphate in the x-ray therapy fo tumours Animal ? med radiol 24: 16-19
calcium phosphate [ in the system: Ca(OH)2-H3P)4-KCl-H2O ] 21 7758-23-8 Zhang J 1991
Ion association in calcium phosphate solutions at 37°C. N/A Journal of solution chemistry. 20:5 455-465
monocalcium phosphate 21 7758-23-8Fredeen AH, DePeters EJ and Baldwin RL 1988
Characterization of acid-base disturbances and effects on calcium and phosphorus balances of dietary fixed ions in pregnant or lactating does goats J Anim Sci 1988. 66:159-173
dicalcium phosphate (DCP) 22 7757-93-9 Averill H.M. And Bibby B.G. 1964A clinical test of addition of phosphates to the diet of children human J. D. Res suppl to num 6, 43: 1150-1155
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-18
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
dicalcium phosphate (DCP) 22 7757-93-9 Muhler J.C. 1957effect on dental caries of a dentifrice containing stannous fluoride and dicalcium phosphate human J. D. Res. 36(3): 399-402
dicalcium phosphate dihydrate 22 7789-77-7 Richardson A.S. Et al 1972Anticariogenic effect of dicalcium phosphate dihydrate chewing gum: result after two years human J Canad Dent Asso 6:
dicalcium phosphate (DCP) 22 7757-93-9 Bullock CH and Kamienski FX 1972Initial submission: Primary skin irritation of sodium hexametaphosphate, powdered, in rabbits Rabbits Stauffer Western RC NTIS OTS0555931 (T-1861)
dibasic calcium phosphate dihydrate 22 7789-77-7 Bell L.C. And Black C.A. 1970
Transformation of dibasic calcium phosphate dihydrate and octacalcium phosphate in slightly acid and alkaline soils soil soil sci soc amer proc 34: 583-587
dicalcium phosphate 22 231-826-1 Fishwick G and Hemingway RG 1973
Urea phosphate and mono-ammonium phosphate as dietary supplements for sheep fed diets inadequate in phosphorous and nitrogen Sheep J. agric. Sci. Cam. 81: 139-143
dicalcium phosphate 22 7757-93-9Carstairs JA, Neitzel RR and Emery RS 1981
Energy and Phosphorus Status as Factors Affecting Postpartum Performanceand Health of Dairy Cows cows Journal of Dairy Science. 64(1)
dicalcium phosphate 22 7757-93-9Cerosaletti PE, Fox DG and Chase LE 2004
Phosphorus Reduction Through Precision Feeding of Dairy Cattle cows J. Dairy Sci. 87:2314–2323
dicalcium phosphate 22 7757-93-9N. R. Combs, E. T. Kornegay, M. D. Lindemann and D. R. Notter 1991
Calcium and phosphorus requirement of swine from weaning to market weight: I. Development of response curves for performance pig J Anim Sci 1991. 69:673-681.
dicalcium phosphate 22 7757-93-9 Crenshaw TD 1986
Reliability of Dietary Ca and P Levels and Bone Mineral Content as Predictors of Bone Mechanical Properties at Various Time Periods pig J Nutr. 116:2155-2170
dicalcium phosphate 22 7757-93-9 G. A. Reinhart and D. C. Mahan 1986
Effect of various calcium:phosphorus ratios at low and high dietary phosphorus for starter, grower and finishing swine pig J. Anim. Sci. 1986.63:457-466
Dicalcium phosphate dust (DCP) 22 7757-93-9 NTIS 1974Health hazard evaluation/toxicity determination. Arco polymer incorporated , Monaca, Pennsylvania N/A N/A
dicalcium phosphate (DCP) 22 7757-93-9 Bennett AC and Adams F 1976
Solubility and solubility product of dicalcium phosphate dihydrate in aqueous solutions and soil solutions. Soil Sci Soc Am J. 40(1): 39-42
Dicalcium phosphate, Defluorinated phosphate
22 7757-93-9 Coon CN et al 2007
The determination of retainable phosphorus, relative biological availability, and relative biological value of phosphorus sources for broilers chicken Poult. Sci. 86:857-868.
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-19
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
dicalcium phosphate (DCP) 22 7757-93-9 Domontovitch MK and Sarubina OV 1925Versuche zur ermittlung loslichkeitsproducts von dicalciumphosphat N/A Biochem Z. 163: 646-9
dicalcium phosphate (DCP) 22 7757-93-9 Greenwald I 1963The instability constant and hydrogen ion dissociation of calcium hydrogen phosphate. N/A J Phys Chem. 67:2853-2854
Calcium hydrogenorthophosphate dihydrate (DCP) 22 7757-93-9 Gregory TM et al 1970
Solubility of CaHPO4.2H2O in the system Ca(OH)2-H3PO4-H2O, at 5, 15, 25, and 37.5°C. J. Res. Nat. Bur. Stand – A. N/A
Journal of Research of the National Bureau of standards. A. Physics and Chemistry. 74A(4): 461-475.
dicalcium phosphate (DCP) 22 7757-93-9 Grobben AH et al 2006
Inactivation of Transmissible Spongiform Encephalopathy agents during the manufacture of Dicalcium phosphate from bone. Hamster and mouse Veterinary Record, 158: 361-366
dicalcium phosphate (DCP) 22 7757-93-9 Hemingway R.G. Et al 1967ABSTRACT: magnesium ammonium phosphate as a mineral supplement for growing lambs Nutrition society: 24
dicalcium phosphate (DCP) 22 7757-93-9 Johnson RJ and Karunajeewa H 1985The effects of dietary minerals and electrolytes on the growth and physiology of the young chick. Chicken J. Nutr. 115: 1680 – 1690
dicalcium phosphate dihydrate (DCP) 22 757-93-9 Lima FR et al 1995
Chemical and Physical Evaluations of Commercial Dicalcium Phosphates as Sources of Phosphorous in Animal Nutrition. N/A Poultry Sci, 47: 1659-167
dicalcium phosphate, defluorinated phosphate 22 7757-93-9 Miller MW and Joukovsky VV 1953
Availability of phosphorus from various phosphate materials chicken Poultry Sci. 32:78-81
calcium phosphate dihydrate 22 7789-77-7 Moreno EC and Osborn G 1963
solubility of gypsum and dicalcium phosphate dihydrate in the system CaO-P2O5-SO3-H2O and in soils. Soil Sci soc Am J. 27:614-619
Dicalcium phosphate dihydrate 22 7789-77-7 Moreno EC, Brown WE and Osborn G 1960solubility of dicalcium phosphate dihydrate in aqueous systems. Soil sci Soc Am J. 24:94-98
Dicalcium phosphate (DCP) 22 7757-93-9 Rindell MA 1902
Sur la solubilité du phosphate bicalcique dans l’eau pure. On the solubility of dicalcium phospahte in pure water.
N/A Comptes Rendus de l’Acad. Sci. 134:112-114.
dicalcium phosphate dihydrate 22 7789-77-7 Tung M.S. Et al 1985Hydrolysis of dicalcium phosphate dihydrate in the presence or absence of calcium fluoride water J. Dent. Res. 64(1): 2-5
dicalcium phosphate (DCP) 22 7757-93-9 Wallner-Pendleton E.A. Et al 1989Toxicity of excess dicalcium Phosphate in the Diet of Turkey Poults turkey avian diseases 33: 375-378
dicalcium phosphate 22 7757-93-9Wilcox RA, Carlson CW, Kohlmeyer WM and Gastler GF 1955
The availability of phosphorus from different sources for poults fed practical-type diets turkey Poultry Science. 34: 1017-1023
dicalcium phosphate dihydrate 22 7789-77-7 Zhang J 1994Unexpected pH dependence of dissolution kinetics of dicalcium phosphate dihydrate. J. Phys. Chem, 98
dicalcium phosphate (DCP) 22 7757-93-9 Zhang J 1992Dissolution deceleration of calcium phosphate crystals at constant undersaturation N/A Journal of crystal growth. 123: 59-68
dicalcium phosphate (DCP) 22 7757-93-9 Zhang J 1992Interpretation of dissolution kinetics of dicalcium phosphate dihydrate. N/A Journal of Crystal Growth. 125. 251-269
dicalcium phosphate monohydrate 22 Anderson GH and Draper HH 1972
Effect of Dietary Phosphorus on Calcium Metabolism in Intact and Parathyroidectomized Adult Rats rat the Journal of nutrition
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-20
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
dicalcium phosphate 22 7757-93-9 Edwards HM and Veltmann JR 1983The Role of Calcium and Phosphorus in the Etiology of Tibial Dyschondroplasia in Young Chicks chicken J Nutr. 113:1568-1575
dicalcium phosphate 22 7757-93-9D. D. Hall, G. L. Cromwell and T. S. Stahly 1991
EFFECTS OF DIETARY CALCIUM, PHOSPHORUS, CALCIUM: PHOSPHORUS RATIO AND VITAMIN K ON PERFORMANCE, BONE STRENGTH AND BLOOD CLOTTING STATUS OF PIGS pig J Anim Sci 1991. 69:646-655.
dicalcium phosphate 22 7757-93-9Hutcheson JP, Greene LW, Carstens GE and Byers FM 1992
Effects of zeranol and two dietary levels of calcium and phosphorus on performance, carcass and bone characteristics, and calcium status in growing lambs sheep J Anim Sci 1992. 70:1346-1351.
dicalcium phosphate 22 7757-93-9 Krishinaro GVG and Draper HH 1972Influence of Dietary Phosphate on BoneResorption in Senescent Mice mice J. NUTRITION,102: 1143-1146.
dicalcium phosphate, monosodium phosphate 22 7757-93-9 Barton BA, Jorgensen NA & DeLuca HF 1987
Impact of Prepartum Dietary Phosphorus Intake on Calcium Homeostasis at Parturition cows J Dairy Sci 70:1186-1191
tricalcium phosphate (refers by CAS No. to ß-TCP) 23 7758-87-4 Brusick D 1976
Mutagenic evaluation of compound. FDA 75-30, tricalcium phosphate, NF,FCC
S. typhimuium, Saccharomyces cerevisiae Litton Bionetics Inc. NTIS PB257879
tricalcium bis(orthophosphate) 23 7758-87-4 Ogino C. et al 1979availability of dietary phosphorus in carp and rainbow trout fish B. Jap. Soc. Scient. Fisheries 45(12): 1527-1532
tricalcium bis(orthophosphate) (ß-TCP) 23 7758-87-4 Bohner M 1997 Kinetics of dissolution of ß-tricalcium phosphate. Journal of colloidal and interface science. 190: 37-48
tricalcium phosphate (TCP) 24 1306-06-5 Bullock CH and Kamienski FX 1972Initial submission: Primary skin irritation of sodium hexametaphosphate, powdered, in rabbits Rabbits Stauffer Western RC NTIS OTS0555931 (T-1861)
HAP (24) (also looks at fluorinated compounds in comparison to HAP) 24 1306-06-5
Jantova S, Theisova M, Letasiova S, Birosova L and Palou TM 2008
and hydroxyapatite on colony formation, DNA damage and mutagenicity. microorganisms Mutation Research. 625:139-144
tricalcium phosphate (as ‘posture’) 24 12167-74-7 O’Connell MA et al 1989Gastrointestinal tolerance of oral calcium supplements human Clin pharm. 8: 425-427.
Ossopan’ - microcrystalline hydroxyapaptite 24 1306-06-5
Reid IR, Hannan SF, Shooler BA and Ibbertson HK 1986
The acute biochemical effects of four proprietary calcium preparations. human Aust NZ J Med. 16:
tricalcium phosphate (TCP) 24 12167-74-4 Sasaoka K. et al 1989an immunological study of tricalcium phosphate supplied by three different manufacturers guinea pigs J. Clin. Lab. Immunol. 30: 197-202
tricalcium phosphate 24 235-330-6Mallaiah K.V., Padma Rami Y. and Vijaya Lakshmi M. 1981
Effect of phosphorous nutrition on growth and sporulation of Alternaria macrospora and Drechslera rostrata fungus indian j. microbiol 21: 169-170
tricalcium phosphate (TCP) 24 12167-74-4 Bano, A., Majumder, S.K. 1965 pathological changes induced in insectsT. Castaneum, C. Cephalonica, E. Cautella J. of Invertebrate pathology 7
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-21
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Tricalcium phosphate, Defluorinated phosphate rock, defluorinated superphosphate,
24 12167-74-7 Bird HR, Mattingly JP 1945
Nutrative evaluation of deflourinated phosphates and other phosphorous supplements. II. Defluorinated phosphates chicken J Assoc of Agric Chem. 28:118-129
hydroxyapatite (HAP) 24 1306-06-5 Boskey AL 1976 Formation of hydroxyapatite at low supersaturation. N/A The Journal of physical chemistry. 80:1 40-45
hydroxyapatite (HAP) 24 1306-06-5 Budz JA 1988The mechanism of dissolution of hydroxyapatite and carbonated apatite in acidic solutions. N/A Journal of crystal growth. 91:490-496
HAP (Gen-OxTM – natural, HA-U-synthetic) 24 1306-06-5 Cabral da Cruz AC et al 2006
Physico-chemical characterization and biocompatibility evaluation of hydroxyapatites N/A Journal of Oral Science. 48(4): 219-226
hydroxyapatite (HAP) 24 1306-06-5 Clark JS 1955 Solubility criteria for the existence of hydroxyapatite. N/A Canadian journal of chemistry. 33:1696-1700
Hydroxyapatite (HAP) 24 1306-06-5 Clark LM and Gerrard WF 1938The preparation of hydroxyapatite, 3[Ca3(PO4)2], Ca(OH)2 N/A J Soc Chem Ind, 7: 295-297
tricalcium phosphate (TCP) 24 1306-06-5 Danneel H and Frohlich KW 1930 Uber das system tricalcium phosphat und wasser N/A Z. Anorg Chem 188:14-31
hydroxyapatite (HAP) 24 1306-06-5 Dutta. S., Sasisekharan V. 1982structure of DNA – binding to hydroxyapatite as a probe calf thymus DNA Indian Journal of biochemistry and biophysics 19: 71-74
hydroxyapatite (HAP) 24 1306-06-5 Elliott JC, Wilson RM and Dowker SEP 2002 Apatite structures N/A JCPDS-International Centre for Diffraction Data 2002, Advances in X-ray analysis. 45: 172-
Hydroxyapatite (HAP) 24 1306-06-5 Evans EJ 1990Toxicity of Hydroxyapatite in vitro : the effect of particle size. N/A Biomaterials, 12: 574-576
Hydroxyapatite (HAP) 24 1306-06-5 Evans EJ et al 1991Studies on the Mechanisms of cell damage by finely ground Hydroxyapatite Particles in vitro N/A Clinical materials, 7: 241-245
hydroxyapatite (HAP) 24 12167-74-4 Fowler BO 1973
Infrared studies of apatites. I. Vibrational assignments for calcium, strontium and barium hydroxyapatites utilising isotopic substitution n/a Inorganic Chemistry. 13:194-214
Hydroxyapatite (HAP) 24 1306-06-5 Francis MD 1965Solubility behaviour of dental enamel and other Calcium Phosphates N/A Ann NY Acad Sci, 131(2): 694-712
tricalcium phosphate (TCP) 24 12167-74-7 Hardy RW and Shearer KD 1985
Effect of dietary calcium phosphate and zinc supplementation on whole body zinc concentration of rainbow trout (Salmo gairdneri). fish Can. J. Fish. Aquat. Sci. 42: 181-185
Dental materials which contain tricalcium phosphate 24 12167-74-7 Heil J 1996 Genotoxicity of dental materials N/A Mutation Research 368: 181-194
Hydroxyapatite (HAP) 24 1306-06-5 La Mer VK 1962 The Solubility behaviour of hydroxylapatite N/A J Phys Chem, 55: 973-978
tricalcium phosphate (TCP) 24 12167-74-4 Majumder S.K., Bano A. 1966reversion of the toxicity of tricalcium phosphate to insects by Trehalose insects Nature 210: 1052-1053
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-22
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
hydroxyapatite (HAP) 24 1306-06-5 Manley MT 1993Calcium phosphate biomaterials: a review of the literature. Hydroxylapatite coatings in orthopaedic surgery. 1-23
Hydroxyapatite (HAP) 24 1306-06-5 McCarthy G 2001Biological effects of calcium hydroxyapatite crystals in breast cancer
hydroxyapatite (HAP) 24 1306-06-5McDowell H, Gregory TM and Brown WE 1977
solubility of Ca5(PO4)3OH in the system Ca(OH)2-H3PO4-H2O at 5, 15, 25 and 37°C. N/A
Journal of research of then Nation Bureau of Standards A. Physics and Chemistry. 81A (2 and 3): 273- 281
hydroxyapatite (HAP) 24 1306-06-5 Morgan M.P. 2001
calcium hydroxyapatite promotes mitogenesis and matrix metalloproteinase expression in human breast cancer cell lines human tissue cells molecular carcinogenesis 32: 111-117
hydroxyapatite (HAP) 24 1306-06-5Niwa S, Sawai K, Takahashi H, Tagai H, Ono M and Fukuda Y 1980
Experimental studies on the implementation of hydroxyapatite in the medullary canal of rabbits. rabbit
tricalcium phosphate (TCP) 24 12167-74-4Rao M.R., Venugopal J.S. And Majumder S.K. 1971
Influence of the purity of tricalcium phosphate on its toxicity to stored-product insects insect (tribolium) Life science 10(II): 1081-1088
basic calcium phosphate (HAP) 24 1306-06-5Rootare HM, Deitz VR and Carpenter FG 1962
solubility product phenomena in hydroxyapatite water systems. N/A Journal of colloid science. 17:179-206
tricalcium phosphate (TCP) 24 1306-06-5 Satoh S et al 1987Effect of dietary tricalcium phosphate on availability of zinc to rainbow trout fish Nippon Suisan Gakkaishi. 53(7): 1199-1205
tricalcium phosphate (TCP) 24 1306-06-5 Satoh S et al 1989
Effect of supplemental phytate and/or tricalcium phosphate on weight gain, feed efficiency and zinc content in vertebrae of channel catfish. fish Aquaculture. 80: 155-161
hydroxyapatite (HAP) 24 1306-06-5 Smith AN 1975The estimation of acid needed to obtain a saturated solution in equilibrium with solid hydroxyapatite. N/A Journal of Colloid and Interface Science, 54:2
hydroxyapatite (HAP) 24 1306-06-5 Smith AN 1977A model describing the kinetics of dissolution of hydroxyapatite. N/A Journal of Colloid and Interface Science, 62:3
hydroxyapatite (HAP) 24 1306-06-5 Smith RN 1974Incongruent dissolution and surface complexes of hydroxyapatite N/A Journal of Colloid and Interface Science, 48:3
hydroxyapatite (HAP) 24 1306-06-5 Stewart BW 1976Short-term carcinogen-induced structural changes in DNA in vivo. N/A IARC Scientific Publications. No. 12 : 343-350
24: HAPdi- and tri- Magnesium phosphate 24 1306-06-5 Taylor AW 1963
Solubility products of di—and trimagnesium phosphates and the dissociation of magnesium phosphate solutions. N/A Trans Faraday Soc. 59: 1580-1584
hydroxyapatite (HAP) 24 1306-06-5 Thomann JM 1990Kinetics of dissolution of calcium hydroxyapatite powder. III: pH and sample conditioning effects N/A Calcif Tissue Int. 46:121- 129.
hydroxyapatite / TCP 24 12167-74-7Toth JM, Hirthe WM, hubbard WG, Brantley WA & Lynch KL 1991
Determination of the ratio of HA/TCP mixtures by x-ray diffraction n/a Journal of Applied Biomaterials. 2:37-40
tricalcium phosphate 24 12167-74-7Satoh SH, Izume K, Takeuchi T and Watanbe T 1992
Effect of Supplemental Trica1cium Phosphate on Zinc and Manganese Availability to Common Carp fish Nippon Suisan Gakkaishi. 58(3): 539-545
Calcium Pyrophosphate 25 14866-19-4 Bachelet CM et al 1987
Sequential study of Pleural Peritoneal and blood cells in acute pleurisy Induced by Calcium Pyrophosphate in the Rat. rat Experimental Lung Research, 13:241-252
calcium acid phosphate (CAPP) 25 14866-19-4 Ship I.I. And Mickelsen O. 1964the effects of calcium acid phosphate on dental caries in children: a controlled clinical trial human J. D. res suppl num 6, 43: 1144-1149
Calcium pyrophosphate dihydrate (monoclinic), calcium pyrophosphate dihydrate (triclinic) and calcium pyrophosphate anhydrous (β) 26
Roch-Arveiller M, Legros R, Chanaud B, Muntaner O, Strzalko S, Thuret A, Willoughby DA and Giroud JP 1990
Inflammatory reactions induced by various calcium pyrophosphate crystals. rat Biomed and Pharmacother. 44: 467-474
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-23
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monoclinic or triclinic calcium pyrophosphate dihydrate crystals, ‘apatitie’ crystals (could be HAP, fluoroapatite, chlorapatite or bromapatite – not stated) 26
Watanabe W, Baker DG and Schumacher HR 1992
Comparison of the acute inflammation induced by calcium pyrophosphate dihydrate, apatite and mixed crystals in the rat air pouch model of a synovial space chicks J Rhumatol 19(9): 1453-1457
Ferric phosphate (FeP) 27 10045-86-0 Bullock CH and Kamienski FX 1972Initial submission: Primary skin irritation of sodium hexametaphosphate, powdered, in rabbits Rabbits Stauffer Western RC NTIS OTS0555931 (T-1861)
Ferric phosphate (FeP) 27 10045-86-0 Langan MA and Shaw EM 2006
Responses of the earthworm Lumbricus terrestris (L.) to iron phosphate and metaldehyde slug pellet formulations. earthworms Applied soil ecology, 34: 184-189
iron phosphate (FeP) 27 10045-86-0 Brusick D 1975Mutagenic evaluation of compound FDA 73-84 Ferric ortho phosphate white food grade, phase I Yeast and Bacteria NTIS
Sodium iron pyrophosphateFerric orthophospahte
27 10045-86-0 Pennell MD et al 1976Biological Availability of Iron Supplements for Rats, Chicks and Humans Rats, chicks, humans Journal of Nutrition, 106(2): 265-274
Iron phosphate (FeP) 27 10045-86-0 Caldwell B 2001A new low-toxicity slug control material for strawberries. Slug NYS IPM program
Iron phosphate (FeP) 27 10045-86-0 Dunkel VC et al 1999Genotoxicity of Iron Compounds in Salmonella Typhimurium and L5178Y Mouse Lymphoma Cells mouse Environmental and Molecular Mutagenesis, 33: 28-41
iron phosphate (FeP) 27 10045-86-0 Edwards CA et al 2009The relative toxicity of metaldehyde and iron phosphate-based molluscicides to earthworms Earthworms Crop protection, 28: 289-294
Iron phosphate (FeP) 27 10045-86-0 Fritz JC et al 1975 Estimation of the bioavailability of iron. Journal of the AOAC. 58(5): 902-905
iron phosphate (FeP) 27 10045-86-0 Speiser B and Kistler C 2002Field tests with a molluscicide containing iron phosphate Slug Crop protection 21: 389-394
Ferric phosphate (FeP) - hydrate 27 51833-68-2Seifried HE, Seifried RM, Clarke JJ, Junghans TB and San RHC. 2006
A compilation of two decades of mutagencity test resuls with the Ames Salmonella typhimurium and L5178Y Mouse lymphoma cell mutation assays.
bacteria salmonella (ames test), mouse lymphoma cells Chem. Res Toxicol. 19: 627-644
Ferric phosphate (FeP) 27 10045-86-0 Prepared for the EU Commission 2002Review report for the active substance ferric phosphate Human European Commission
Iron phosphate (FeP) 27 10045-86-0 Carter SR and Hartshorne NH 1923The System Ferric Oxide-Phosphoric Acid – Water. A New Phosphate N/A J Chem Soc Trans 123: 2223-2233
Iron phosphate (FeP) 27 10045-86-0 Chang SC and Jackson ML 1957 Solubility product of iron phosphate. water and soil Soil Sci Soc Am J. 21:265-269
Ferric phosphate (FeP) 27 10045-86-0 Hazardous Substances Data Bank, 2004 Hazardous Substances Data Bank, Ferric phosphate Human TOXNET
Ferric phosphate (FeP) 27 10045-86-0 Jameson RF and Salmon 1954
complexes invloving tervalent iron and orthohposphoric acid. Part III. The system ferric oxide-phosphoric oxide-water at 25° N/A J Chem Soc. Unknown vol: 28-34
Ferric phosphate (FeP) 27 10045-86-0 Mahoney AW and Hendricks DG 1976Effect of dietary iron level on efficiency of converted food iron into haemoglobin by the anaemic rat. rat Nutr. Metabol. 20: 222-227
Iron phosphate (FeP) 27 10045-86-0 N/A 1997Environmental fate - Ecotoxicology - Human Health Ferric Phosphate PPDB
Rat, bird, fish, aquatic invertebrates, algae, earthworms, arthropods, human PPBD (data base)
Ferric phosphate (FeP) 27 10045-86-0 Prepared for the EU Commission 2002Review report for the active substance ferric phosphate Rat European Commission
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-24
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Ferric phosphate (FeP) 27 10045-86-0 Prepared for the EU Commission 2002Review report for the active substance ferric phosphate
Mouse, hamster, guinea pig European Commission
iron phosphate (FeP) 27 10045-86-0 Ridgway LP and Karnofsky DA 1952The effects of metals on the chick embryo: toxicity and production of abnormalities in development. chick embryo Ann N Y Acad Sci: 203-215
Iron phosphate (FeP) 27 10045-86-0 Rodriguez E et al 2007An iron-based T1 contrast agent made of iron-phosphate complexes: In vitro and in vivo studies. mice Magn reson Mater Phy, 20: 27-37
Iron phosphate (FeP) 27 10045-86-0 Rohner F et al 2007Synthesis, Characterization, and Bioavailability in Rats of Ferric Phosphate Nanoparticles Rats The Journal of Nutrition, 137: 614-619
iron phosphate (FeP) 27 10045-86-0 Salmon JE 1952
complexes invloving tervalent iron and orthophosphoric acid. Part II. Ion-exhange studies of solutions containing phosphate and chloride n/a J Chem soc: 2644-2650
Iron phosphate (FeP) 27 10045-86-0 Tamm L and Speiser B 2006Provisional Evaluation of the use of "Ferramol Schneckenkorn" in Organic Farming in Switzerland. Slugs/snails
Research Institute of Organic Agriculture (FiBL), Frick, Switzerland
Iron pyrophosphate (FePP) 28 10058-44-3
Fidler MC, Walczyk T, Davidsson L, Zeder C, Sakaguchi N, Juneja LR and Hurrel RF 2004
A micronized, dispersible ferric pyrophosphate with high relative bioavailability in man. human British Journal of Nutrition. 91:107-112
Ferric pyrophosphate (FePP) 28 10058-44-3 Motoya T et al 2000
Effects of Ascorbic acid on Interactions between Ciprofloxacin and Ferrous Sulphate, Sodium Ferrous Citrate or Ferric Pyrophosphate, in mice. mice J Pharm Pharmacol 52:397-401
ferric pyrophosphate (FePP) 28 10058-44-3 Wegmuller R et al 2006
Salt Dual-Fortified with Iodine and Micronized Ground Ferric Pyrophosphate Affects Iron Status but Not Hemoglobin in Children in Cote d'Ivoire. Human Journal of Nutrition, 136(7): 1814-1820
Iron pyrophosphate (FePP) 28 10058-44-3Kitano K, Fukukawa T, Ohtsuji Y, Matsuda T and Yamaguchi H 2002
Mutagenicity and DNA-damaging activity caused by deomposed products of potassium sorbate reacting with ascorbic acid In the presence of Fe salt.
bacteria salmonella (ames test) Food and chemical toxicology 40: 1589-1594
dimagnesium phosphate (DMP) 29 7757-86-0Chow FC, Taton GF, Baulay JP, Lewis LD, Remmenga EE and Hamar DW 1980
Effect of dietary calcium, magnesium and phosphorous on phosphate urolithiasis in rats. rat Investigative Urology. 17(4): 273-276
dimagnesium phosphate (DMP) 29 7757-86-0Halliwell DJ, Mackelvie ID, Hart BT and Dunhill RH 1996
Separation and detection of condensed phosphates in waste waters by ion chromatography coupled with flow injection. n/a Analyst. 121:1089-1093.
Phosphoric acid, sodium phosphates, potassium phosphates, calcium phosphates, monomagnesium phosphate, dimagnesium phosphate, diphosphates, triphosphates and polyphosphates 29 7757-86-0
Food additives in Europe 2000 - status of safety assessments of food additives presently permitted in the EU.
trimagnesium bis(orthophosphate) (TMP) 30 7756-87-1 Bullock CH and Kamienski FX 1972
Initial submission: Primary skin irritation of sodium hexametaphosphate, powdered, in rabbits Rabbits Stauffer Western RC NTIS OTS0555931 (T-1861)
manganese phosphate (hureaulite) (MMangP) 34 18718-07-5 Dorman D.C. Et al 2004(a)
Nasal toxicity of manganese sulphate and manganese phosphate in young male rats following subchronic (13 week) inhalation exposure rats inhalation toxicology 16(6): 481-488
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-25
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
manganese phosphate (hureaulite) (MMangP) 34 18718-07-5 Dorman DC et al 2004(b) 30 and 90 day inhalation exposure rats
manganese phosphate (hureaulite) (MMangP) 34 18718-07-5 Normandin L. et al 2002
Assessment of bioaccumulation, neuropathy, and neurobehavious following subchronic (90 days) inhalation in Sprague-Dawley rats exposed to manganese phosphate Rats Toxicology and applied pharmacology 183: 135-145
manganese phosphate (hureaulite) (MMangP) 34 18718-07-5 Viteralla D 2000 5 and 7 week inhalation exposure rats
Manganese phosphate (MMangP) 34 18718-07-5 Boyle FW and Lindsay WL 1985Diffraction patterns and solubility products of several divalent manganese phosphate compounds. N/A Soil Sci Soc Am J. 49(3): 761-766
Manganese phosphate (MMangP) 34 18718-07-5 Boyle FW and Lindsay WL 1986Manganese phosphate equilibrium relationships in soils. SOIL Soil Sci Soc Am J. 50(3): 588-
manganese III phosphate (MMangP) 34 18718-07-5 Boyle FW and Lindsay WL 1985Preparation, x-ray diffraction pattern and solubility product of manganese (III) phosphate hydrate. N/A Soil Sci Soc Am J. 49: 758-760
manganese hydrogen phosphate (DMangP) 35 51349-94-1 Grube G and Staesche M 1927
Das ternare system manganophosphate-phosphorsaure-wasser und die diphosphatomanganosaure. N/A Z Physik Chem. 13:572-583
dicopper hydroxide phosphate (CuHP) 38 12158-74-6 Huerin H and Kozicki H 1952Chimie minerale - sur les orthohposphates du cuivre. Etude du systeme P2O5-Ocu-OH2 a 60 et 18° N/A Compt Rend 235: 52-1952
aluminium phosphate (MALP) 39 13530-50-2 Drinker P 1953Article: Dale JC and King EJ. Acute toxicity of mineral dusts. mice
Archives of Industrial Hygiene and Occupational Medicine Vol 7: 478-483
Aluminium orthophosphate (TALP) 40 7785-30-7 Kada T, Hirano K and Shirasu Y 1980Screening of environmental chemical mutagens by the Rec-Assay system with Bacillus subtilis bacteria Chem Mutagens. 6:149-173
Aluminium orthophosphate (TALP) 40 7785-30-7 Kanematsu N, Hara M and Kada T 1980Rec assay and mutagenicity studies on metal compounds bacteria Mutation Research .77:109-116
Aluminium phosphate (TALP) 40 7784-30-7 Greger JL, Bula EN and Gum ET 1985
Mineral metabolism of rats fed moderate levels of various aluminium compounds for short periods of time. Rat J. Nutr. 115:1708-1716
Aluminium orthophosphate (TALP) 40 7785-30-7Brosheer JC, Lenfesty FA and Anderson JF 1954
Solubility in the system aluminium phosphate-phosphoric acid-water N/A J Am Chem Soc. 76:5951-5956
Aluminium orthophosphate (TALP) 40 7784-30-7 Guerin H and Martin R 1952 Chimie minerale - sur les phosphates d'aluminium N/A Compt Rend. 234:1777-9
Aluminium orthophosphate (TALP) 40 7785-30-7 Masten S 2000Aluminium compounds, Review of Toxicological Literature Abridged Final Report Some human
Aluminium orthophosphate (TALP) 40 7785-30-7 Mooney RCL 1956The crystal structure of aluminium phosphate and gallium phosphate, low-cristobalite type N/A Acta Cryst. 9: 728
Aluminium orthophosphate (TALP) 40 7785-30-7Tsuhako M , Motooka I and Kobayashi M 1973
Studies of the preparation and physical properties of multivalent metal condensed phosphates. V. The grinding of various aluminium phosphates. n/a Bulletin of the Chemical Society of Japan. 46: 2343-2346
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-26
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Aluminium orthophosphate (TALP) 40 7785-30-7Yayt BB et al
1999 62: 37-39COULD NOT BE TRANSLATED Experimental and Clinical Pharmacology. 62: 37-39
Aluminium tripolyphosphate 41 13939-25-8Tsuhako M , Hasegawa K, Matsuo T, Motooka I and Kobayashi M 1975
Studies of the preparation and physical properties of multivalent metal condensed phosphates. XI. The preparation of various aluminium phosphates and their thermal transformation N/A
Bulletin of the Chemical Society of Japan. 48(6): 1830-1835
Aluminium metaphosphate 42 13776-88-0 Van Der Meer H 1976 Acta Cryst. B25: 2423-2426 n/a Acta Cryst. B25: 2423-2426
sodium aluminium phosphate (SALP) 43 7785-88-8 Katz A.C. Et al 1984a six month dietary toxicity study of acidic sodium aluminium phosphate in beagle dogs dogs (beagle) Fd. Chem. Toxic. 22(1): 7-9
sodium aluminium phosphate (SALP, acidic, levair) 43 7785-88-8 Brusick D 1975
Mutagenic evaluation of compound. FDA 75-1. 007785-88-8, sodium aluminium phosphate (acidic) F.C.C. grade levair
S. typhimuium, Saccharomyces cerevisiae Litton Bionetics Inc. NTIS PB254520
sodium aluminium phosphate (SALP) 43 7785-88-8 Pettersen J.C. Et al 1990Twenty-six week toxicity study with KASAL in beagle dogs dogs
Environmental Geochemistry and Health, ISSN 0269-4042 (Print) 1573-2983 (Online), 12 ( 1-2): 121-123
Basic Sodium Aluminium Phosphates (SALP);KASAL and KASAL II. These are autogenous mixtures of alkaline sodium aluminium phosphate and dibasic sodium phosphate. KASAL contains approx 6% Al and KASAL II contains approx 13% Al.
43 7785-88-8 Hicks JS et al 1987
Toxicity and Aluminium concentration in bone following dietary administration of two sodium aluminium phosphate formulations in rat. rat Fd chem toxic, 25(7): 533-538
sodium aluminium phosphate (SALP) 43 7785-88-8 Yokel R.A. And Florence R.L. 2006
Aluminium bioavailability from the approved food additive leavening agent acidic sodium aluminium phosphate, incorporated into a baked good, is lower than from water Rats Toxicology 227: 86–93
Acidic sodium aluminium phosphate (SALP) 43 7785-88-8 Yokel RA 2005 Al bioavailability from food N/A Toxicol Sci 84(1-S): 230-1
sodium aluminium phosphate (SALP) 43 7785-88-8 Yokel RA, Hicks CL, Florence RL 2008
Aluminum bioavailability from basic sodium aluminum phosphate, an approved food additive emulsifying agent, incorporated in cheese rat Food Chem Toxicol. 2008 June ; 46(6): 2261–2266.
sodium aluminium phosphate (SALP) 43 7785-88-8 WHOSodium aluminium phosphate(acidic and basic)(WHO food additives series 1) mouse
sodium calcium polyphosphate 45 23209-59-8 Anon 1990
Initial submission: A two year inhalation toxicity study of calcium sodium metaphosphate fiber in the rat. rat
Biodynamics Inc. Project No. 85-7802. Monsanto Document Id No. 88-920005007.
sodium calcium polyphosphate 45 23209-59-8Gomez F, Vast P, Llewellyn P and Rouquerol F 1997
dehydroxylation mechanisms of polyphosphate glasses in relation to temperature and pressure. n/a Journal of non-Crystalline Solid. 222: 414-421
calcium sodium metaphosphate (CSM) 45 23209-59-8 Nair R.S. Et al 1992Toxicity of calcium sodium metaphosphate fibre. In vitro and in vivo degradation and clearance studies Rats fundamental and applied tox. 19: 69-78
sodium calcium polyphosphate 45 23209-59-8 Unknown author 1986Low fibrosarcoma incidence seen for phosphate fiber test. rat Pesticide and Toxic Chemical News. 8
sodium potassium tripolyphosphate (SKTP) 46 24315-83-1 Gotte H. 1953
research in mammals with radioactive high polymers phosphate markers dogs z naturforsch 8(b):173
disodium fluorophosphate (SFP) 47 10163-15-2Gocke E, King MT, Eckhardt K and Wild D 1981
Mutagenicity of cosmetics ingredients licensed by the European Communities. Mutation Research. 90: 91-109.
disodium fluorophosphate (SFP) 47 10163-15-2Hayashi M, Kishi M, Sofuni T and Ishidate M 1988
Micronucleus tests in mice on 39 food additives and eight miscellaneous chemicals. Mouse Fd Chem. Toxic. 26(6): 487-500.
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-27
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
disodium fluorophosphate (SFP) 47 10163-15-2 Poulsen H & Ericsson Y 1965
Chronic toxicity of dietary sodium monofluorophosphate in growing rats, with special reference to kidney changes rat Acta path. Et microbiol. Scandinav. 65:493-504
disodium fluorophosphate (SFP) 47 10163-15-2
Buchi R.
1977
Induced dominant lethal mutation and cytotoxic effects in germ cells of drosophila melanogaster with trenimon, PDMT and sodium monofluorophosphate. d. melanogaster Gentae genetics,87: 67-81
disodium fluorophosphate (SFP) 47 10163-15-2 Lim J.K. Et al 1978 LD50 in the mouse compared to the rat mice and rats Caries Res. 12: 177-179
disodium fluorophosphate (SFP) 47 10163-15-2 Shourie K.L. Et al 1950preliminary studies of the caries inhibiting potential and acute toxicity of sodium monofluorophosphate hamster J. D. Res 29: 529
disodium fluorophosphate (SFP) 47 10163-15-2Whitford GM, Birdsong-Whitford NL and Finidori C 1990
Acute oral toxicity of sodium fluoride and monofluorophosphate separately or in combination in rats. rat Caries Res. 24: 121-126
disodium fluorophosphate (SFP) 47 10163-15-2 Buchi R. 1977induced dominant lethal mutations and cytotoxic effects in germ cells of Drosophila melanogaster Drosophila melanogaster gentae Genetics 87(): 67
disodium fluorophosphate (SFP) 47 10163-15-2 Ericsson Y and Hammarstrom L 1965The distribution in the mammal body of F18 and P32 from double-labelled Na2PO3F rats and mice Acta physiol. Scand. 65:126-137
disodium fluorophosphate (SFP) 47 10163-15-2 Ericsson Y, Santesson G and Ullberg S 1961
Absorption and metabolism of the PO3F ion in the animal body. Studies with F18, P32-labelled sodium monofluorophosphate. Arch. Oral Biol. Special Supplement. 4:160-174.
disodium fluorophosphate (SFP) 47 10163-15-2Gruninger SE, Clayton R, Chang SB and Siew C 1988
Acute oral toxicity of dentrifrice fluorides in rats and mice. rats, mice J Dent Res. 67:884
disodium fluorophosphate (SFP) 47 10163-15-2 Maynard EA and Downs WL 1951
Short-term feeding studies on sodium fluorophosphate (Na2PO3F) and potassium hexafluorophosphate (KPF6) in rats rat
Atomic Enery Project Rep. UR-200. Q. Tech. rep. US atomic energy commision . Univ Rochester Oct 1-Dec 33: 24-26
disodium fluorophosphate (SFP) 47 10163-15-2 Muhler JC, Weddle DA, Stewart JO 1955Fluorine storage in rats receiving different flourines in the drinking water at varying pH rat J. Dent. Res. 34:895-899
sodium fluoride n/a n/a Pindborg J 1957The effect of 0.05 per cent dietary sodium fluoride on the rat kidney rat Acta pharmacol et toxicol. 13:36-45
disodium fluorophosphate (SFP) 47 10163-15-2 Ruzicka JA, Mrklaus L and Rokytova K 1974
Incorporation of fluoride in bones and teeth and dental fluorosis in mice after administration of complex fluorides mice Archs oral Biol. 19: 947-950
disodium fluorophosphate (SFP) 47 10163-15-2 Setnikar I and Arigoni R 1988Chemical stability and mode of gastrointestinal absorotion of sodium monoflurophosphate. Arzneim Forsch. 38(1): 45-49
disodium fluorophosphate (SFP) 47 10163-15-2Smith FA and Hodge HC (most important article) 1983 Toxicology of monoflurophosphate. various
Caries Res. 17 (Suppl. 1): 36-45 in: Karger S (1983) Monofluorophosphate perspectives. Caries Research. Journal of the European Organisation for Caries Research. (Filename: Nijmegen caries research)
disodium fluorophosphate (SFP) 47 10163-15-2Smith FA, Downs WL, Hodge HC & Maynard EA 1960
Screening of fluorine-containing compounds for acute toxicity mice Toxicity and Applied Pharmacology. 2 : 54-58
sodium fluorophosphate 47 10163-15-2 Smith GE 1985Toxicity of fluoride-containing dental preparations: a review. various The science of the total environment. 43:41-61
disodium fluorophosphate (SFP) 47 10163-15-2 Zipkin I & Likins RC 1957Absorption of various fluorine compounds from the gastrointestinal tract of the rat rat Am J Physiol. 191: 547-550
Sodium monofluorophosphate (SFP) 47 10163-15-2 Boulétreau PH et al 2006
Fluoride exposure and bone status in patients with chronic intestinal failure who are receiving home parenteral nutrition. human Am J Clin Nutr 83:1429-1437
sodium fluoride n/a n/a Jones CA et al 1988Sodium fluoride promotes morphological transformation of Syrian Hamster embryo cells. hanster Carcinogenesis 9(12): 2279-2284
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-28
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
disodium fluorophosphate (SFP) 47 10163-15-2Stookey G.K., Hudson J.T. and Muhler J.C. 1967
Laboratory Studies Concerning the Effectiveness and Safety of Various Fluoride and Fluoride-Phosphate Systems. human, rat J. Dent. Res., 46(3): 503-513
sodium fluorophosphate (SFP) 47 10163-15-2 WHO 1982Inorganic fluorides used in drinking water and dental preparations N/A
disodium fluorophosphate (SFP) 47 10163-15-2 Zipkin I & McClure FJ 1951Complex fluorides: caries reduction and fluorine retention in the bones and teeth of white rats rat Public Health Reports. 66(47): 1523-1532
phosphoric acid 48 7664-38-2 Hill WL, Faust GT and Hendricks SB 1943 Polymorphism of phosphorus oxide, n/a J. Am. Chem. Soc., 65: 797-804.
phosphoric acid 48 7664-38-2 Al-Ani F.Y., Al-Lami S.K. 1988 Absence of mutagenic activity of acidity regulators ames salmonella Mutation research, 206():467-470
phosphoric acid 48 7664-38-2 Alkahem HF 1989Effect of different acids on the freshwater fish Aphanius dispar. fish J Biol Sci Res, 20(3): 537-545
Phosphoric acid 48 7664-38-2 Amato D et al 2001Carbonated Beverage Consumption and Bone Fractures N/A Arch Pediatr Adolesc Med 155(2):200-201
Phosphoric acid 48 7664-38-2 Amato D et al 1998Acute effects on soft drink intake on calcium and phosphate metabolism in immature and adult rats. rats Rev Invest Clin 50: 185-189
phosphoric acid 48 7664-38-2 Arenholt-bindslev D. et al 1987
Toxic effects of two dental materials on human buccal epithelium in vitro and monkey buccal mucosa in vivo human tissue cells scand j dent res 95: 467-474
phosphoric acid 48 7664-38-2 Bonting S.L. 1952the effect of a prolonged intake of phosphoric acid and citric acid in rats Rats dissertation
Phosphoric acid 48 7664-38-2 Brown E.H and Whitt C.D. 1952 Vapour pressure of phosphoric acids. n/a Ind. Eng. Chem. 44,3:615-618phosphoric acid 48 7664-38-2 Bucher K et al 1981 skin irritation potential mice Agents and actions, vol 11, no 5, page 515 onds
phosphoric acid 48 7664-38-2 Caravati M 1987 one acute human toxicity case report humansAnals of Emergency Medicine, 16:8 August 1987, page 119/904
phosphoric acid 48 7664-38-2 Cheremisinoff NP 2000 Handbook of Hazardous chemical properties N/A N/A
Phosphoric acid 48 7664-38-2 Choi JH et al 1979Blood phosphorus levels of laying hens at various time intervals after dosing with phosphoric acid. hens J. Nutr. 109: 1515-1518
Phosphoric acid 48 7664-38-2 Choi JH et al 1978
The phosphorus excretion pattern and balance during one egg cycle of the laying hen fed a phosphorus deficient diet with or without a signle dose of phosphoric acid hens Unknown Journal
phosphoric acid 48 7664-38-2 Christensen JH and Reed RBDensity of aqueous solutions of phosphoric acid. Measurements at 25°C n/a Industrial and Engieneering chemistry. 47(6): 1277-1281
phosphoric acid 48 7664-38-2 Cadtru F 1904L'acide phosphorique. Son innocuite. Sea principlaes indications en therapeutique.
duck, rabbit, horse, guinea-pig, dog, human La Presse Medicale. 74
phosphoric acid 48 7664-38-2 Cipollaro. M. et al 1986
sublethal pH decrease may cause genetic damage to Eukaryotic Cell: A study on Sea Urchins and Salmonella typhimurium
sea urchin (embryo and sperm) and Salmonella typhimurium Teratogenesis, Carciogenesis and Mutagenesis 6: 275-287
phosphoric acid 48 7664-38-2 Demerec. M., Bertani G. and Flint J. 1951a survey of chemicals for mutagenic action on E. Coli bacteria American naturalist 85(821): 119-136 (see 123)
phosphoric acid 48 7664-38-2 Drahoslava Vyskocilova et al 1983 workers IN RUSSIAN humans pracov lek, 35(2):76
phosphoric acid 48 7664-38-2 Ellgaard E.G, Gilmore III J.Y. 1984effects of different acids on the bluegill sunfish, Lepomis macrochirus rafinesque fish j. Fish Biol. 25: 133-137
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-29
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
phosphoric acid 48 7664-38-2 Fabbri L. et al 1977Chronic broncopneumopathy and pneumoconiosis in workers employed in phosphoric acid production human Lavoro Umano 27: 50-57
phosphoric acid 48 7664-38-2 Federal register.55 1990Phosphoric acid; toxic chemical release reporting; community right to know n/a n/a
phosphorous acid 48 7664-38-2 Fedorencko vi et al 1991threshold concentration of phosporous acid in water ? unknown gig sanit 45():24
Phosphoric acid 48 7664-38-2 Fernando GR et al 1999
Consumption of soft drinks with phosphoric acid as a risk factor for the development of hypocalcemia in postmenopausal women human J. Clin. Epidemiol. 52(10):1007-1010.
phosphoric acid 48 7664-38-2 Forsberg C.M. 1982The effect of 50 per cent phosphoric acid on oral soft tissues Rats Swed Dent J Supplement 15
Phosphoric acid 48 7664-38-2 Garcia-Contreras F et al 2000Cola beverage consumption induces bone mineralisation reduction in Ovariectomized rats. human Arch. Med. Res. 31:360-365.
phosphoric acid 48 7664-38-2 Harrison W N., Bradberry S M and Vale J A n/a
Phosphoric acid UKPID monograph. IPCS INTOX databank. n/a
Phosphoric acid UKPID monograph. IPCS INTOX databank.
Phosphoric acid 48 7664-38-2 Heaney RP et al 2001Carbonated beverages and urinary calcium excretion. human Am. J. Clin. Nutr. 74:343-347.
phosphoric acid 48 7664-38-2 Hermann 1947Some paradoxical effects in experimental pharmacology. n/a Experimental Medicine and Surgery.V (2-3):160-162.
phosphoric acid 48 7664-38-2 High production volume information system(HPVIS). Phosphoric acid . n/a HPV phosphoric acid full dossier off web 22-12-08
rat, sheep, rabbit, human, S. typhimurium,
High production volume information system(HPVIS). Phosphoric acid .
Phosphoric acid 48 7664-38-2 Hughes W.F. 1948The tolerence of rabbit cornea for various chemical substances.
Bulletin of The Johns Hopkins Hospital. Appendix I. 82:338-349
phosphoric acid 48 7664-38-2 Iijima S. et al 1993cytotoxicity of phosphoric acid on cultured mamalian cells hamster lungs cells shigaku (odontology) 80(5): 1159-1165
phosphoric acid 48 7664-38-2 Ishii H. et al 1981Measurement of the toxicity of chemicals to the activated sludge micro organisms suishitsu Odaku Kenkyu 4(4 suppl): 197-203
Phosphoric acid 48 7664-38-2 Jacobs G.A 1988 Two dilutions of phosphoric acid tested on eye. J Am. Coll. Toxicol. 11,6:724
phosphoric acid 48 7664-38-2 Jacobs G.A., Martens M.A. 1989An objective method for the evaluation of eye irritation in vivo rabbits Fd. Chem. Toxic. 27(4): 255-258
Phosphoric acid 48 7664-38-2 Jacobson L. and Halmann M. 1982Polyphosphate metabolism in the blue-green alga Microcystis aeruginosa. algae Journal of Plankton Research. 4,3:481-488
Phosphoric acid 48 7664-38-2 JECFA1992, 1995 Phosphoric acid prepared at the 44th JECFA n/a Phosphoric acid prepared at the 44th JECFA
phosphoric acid 48 7664-38-2 Kristensen P 1993 Inorganic Acid AerosolsVarious mamals and humans Nordic Arbete oche Halsa 1: 7-54
phosphoric acid 48 7664-38-2 Larson P.S. Et al 1956
observations on the effect of chemical configuration on the edema-producing potency of acid, aldehydes, ketones and alcohols rabbits j pharmac exp ther 116():119
Phosphoric acid 48 7664-38-2 Libuda L 2008
Association between long-term consumption of soft drinks and variables of bone modeling and remodeling in a sample of healthy German children and adolescents. human Am. J. Clin. Nutr. 88:1670-1677.
phosphoric acid 48 7664-38-2 Loden M. et al 1985The dermal irritancy/corrosion of 20 compounds in acqueous solutions Rabbits FAO rapport E 40023 ISSN 0281-9945
phosphoric acid 48 7664-38-2 Malm O J 1952On phosphates and phosphoric acid as dietary factor in the calcium balance of man. human Unknown Journal
phosphoric acid 48 7664-38-2 Malm OJ 1952 dietary balance calcium and P-acid humans Scand J Clin Lab Invest, 5, pages 75-84
Phosphoric acid 48 7664-38-2 Mazariegos-Ramos et al 1995
Consumption of soft drinks with phosphoric acid as a risk factor for the development of hypocalcemia in children: a case-control study. human The J. Pediatr. 126(6):940-942
phosphoric acid 48 7664-38-2 Morley KM 1999Evaluation of the EPA exposure assessment for phosphoric acid. N/A Regulatory toxicology and Pharmacology. 29: 309-318
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-30
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
phosphoric acid 48 7664-38-2 MsMeniman N.P. 1973The toxic effect of some phosphate supplements fed to sheep sheep Australian Veterinarian J. 49: 150-152
Phosphoric acid 48 7664-38-2 Nims LF 1934
The first dissociation constant for phosphoric acid from 0 to 50°.Nims LF (1933)The second dissociation constant of phosphoric acid from 20 to 50°
N/AJ Am Chem Soc 56: 1110-1112, J Am Chem Soc 55: 1946-1951
condensed phosphoric acids 48 7664-38-2 Parks JR and Van Wazer JR 1957
Structure and properties of the condensed phosphates –reorganization theory and some applications N/A J Am Chem Soc, 79: 4890-97
phosphoric acid 48 7664-38-2 Payne MP, Shillaker RO and Wilson AJ 1993
Phosphoric acid, Phosphorous pentoxide, Phosphorous oxychloride, Phosphorous pentachloride, Phosphorous pentasulphide. various Toxicity Review 30. HSE Books.
phosphoric acid 48 7664-38-2 Randall D.J. And Robinson E.C. 1977ABSTRACT : skin irritation tests on various concentrations of phosphoric acid Rabbits monsanto
phosphoric acid 48 7664-38-2 Reinl W 1956 toxicity IN GERMAN Archiv fur Toxikologie, bd 16, S 158-181
phosphoric acid ( and various non -IP subs) 48 7664-38-2 Sigova N.V. 1983
Toxicological characteristics of phosphoric acid and some of its chromium salts used as a binder in refractory production. human , rat Gig. Truda i Prof. Patol. v Tsv i Cher. Metallurgii, M: 65-69
phosphoric acid ( and various non -IP subs) 48 7664-38-2 Sittig M. 1981 Handbook of toxic and hazardous chemicals. n/a
Handbook of toxic and hazardous chemicals. Noyes Publications, Park Ridge, New Jersey, USA.
phosphoric acid 48 7664-38-2 Slack A.V. 1968 Phosphoric acid (book) n/aPhosphoric Acid Volume I (Parts I & II) Marcel Dekker Inc, New York
phosphoric acid : red phosphorus/butyl rubber mixture 48 7664-38-2 Sterner RT 1993
whole body exposures to a phosphoric acids aerosol: 1. Spontaneous activity effects in wild rodent and avian species. birds, rodents
http://aphis.usda.gov/wildlife_damage/nwrc/publications/93pubs/9337.pdf
phosphoric acid 48 7664-38-2 The EFSA Journal 233.1-19 2005
Opinion of the scientific panel on dietetic products, Nutrition and allergies on a request from the commission related to the tolerable upper intake level of phosphorus. rats The EFSA Journal 233.1-19
Phosphoric acid 48 7664-38-2 Tucker KL 2006
Colas, but not other carbonated beverages, are associated with low bone mineral density in older women: the Framingham Osteoporosis study. human Am. J. Clin. Nutr. 84:936-942.
phosphoric acid 48 7664-38-2 Urben PG (Ed), complied by : Pitt MJ 1999Bretherick's Handbook of reactive chemical hazards. 6th Ed - vol 1. N/A N/A
phosphoric acid 48 7664-38-2 Urben PG (Ed), complied by : Pitt MJ 1999Bretherick's Handbook of reactive chemical hazards. 6th Ed - vol 2. N/A N/A
Phosphoric acid 48 7664-38-2 Vanderzee CE and Quist AS 1961The third dissociation constant of orthophosphoric acid. N/A J Phys Chem 65: 118-123
phosphoric acid 48 7664-38-2 Von Brehm J. and Meijering M.P.D 1982on the sensitivity to low pH of some selected crustaceans (Daphnia and Gammarus, Crustacea) Crustaceans Arch. Hydrobiol. 95(1): 17-27
Phoshphoric acid 48 7664-38-2 Von Burg R. 1992 Toxicology Update: Phosphoric acid/phosphates. various Journal of Applied Toxicology. 12(4) 301-203
phosphoric acid 48 7664-38-2 Weiner M. et al 1988ABSTRACT: Modified skin irritation study on 75% phosphoric acid in a single rabbit rabbit ?
Phosphoric acid 48 7664-38-2 Whiting SJ et al 2001
Relationship between carbonated and other low nutrient dense beverages and bone mineral content of adolescents human Nutr. Res. 21:1107-1115.
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-31
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
phosphoric acid 48 7664-38-2 WHO 1964 WHO Food additives.24.65 human, rat WHO IPCS INCHEM phosphoric acid
Phosphoric acid 48 7664-38-2 Wyshak G 2000Teenaged girls, carbonated beverage consumption and bone fractures human Arch. Pediatr. Adolesc. Med. 154:610-613
phosphoric acid 48 7664-38-2 Guevelard F 1922Toxicite comparee de divers acides pour les poissons (Epinoches) fish CR Acad Sci. 175: 124-1242
phosphoric acid 48 7664-38-2 Nazario G 1952 Agentes acidulantes utilizados em alimentos ? Rev. Inst. Aldolpho, Lutz. 11: 141orthophosphoric acid, pyrophosphoric acid, metaphosphoric acid 48 7664-38-2
Gamgee A, Priestly J and Larmuth L 1877
On the difference in the poisonous activity of phosphorous in ortho-, meta-, and pyro- phosphoric acids n/a Journal of Anatomy and Physiology. 11: 255
phosphoric acid 48 7664-38-2 Townsend LD and Cheyne H 1944
The influence of hydrogen ion concentration of the minimum dissolved oxygen toleration of the silver salmon, Oncorhynchus kisutch (walbum). fish Ecology. 25(4):461-466
phosphoric acid 48
H. R. CROOKSHANK, F. E. KEATING, EARL BURNETT, J. H. JONES ANDR. E. DAVIS 1960
Effect of chemical and enzymatic agents on the formation of urinary calculi in fattening steers
cows J Anim Sci 1960. 19:595-600.Urea phosphate 51 Bremner JM and Douglas LA 1971 Decomposition of urea phosphates in soils. Soil Sci Am J. 35:575-578
Urea phosphate 51Perez CB, Warner RG and Loosli JK 1967
Evaluation of Urea-phosphate as a source of nitrogen and phosphorous for ruminants Cows and Lambs J Animal Science. 26: 810-819
Zinc phosphate 52 13598-37-3 Trail JS and Sausen RE 1962investigation of cavity-sealing abilities of zinc phosphate n/a J D Res. 41(3):525-536
ammonium magnesium phosphate (struvite) 56 7785-21-9 Aage HK, et al 1997 The solubility of struvite. N/A
Journal of radioanalytical and nuclear chemistry. 223(1-2):213-215.
ammonium magnesium phosphate (struvite) 56 7785-21-9 Bouropoulos NC and Koutsoukos PG 2000
Spontaneous precipitation of struvite from aqueous solutions N/A Journal of Crystal Growth. 213: 381-388
ammonium magnesium orthophosphate (struvite) 56 7785-21-9 Bube K 1910 Uber magnesiumammonimphosphate N/A Z. Anal Chem
ammonium magnesium phosphate (struvite) 56 7785-21-9 Buchanan JR et al 1994 Thermodynamics of struvite formation. N/A American Society of Engineers. 37(2): 617-621
ammonium magnesium phosphate (struvite) 56 7785-21-9 Burns JR and Finlayson B 1982
Solubility product of magnesium ammonium phosphate hexahydrate at various temperatures. N/A Journal of Urology. 128: 426-427
ammonium magnesium phosphate (struvite) 56 7785-21-9 Ribbe PH 1969 The decomposition of Struvite: further evidence N/A mineralogical magazine, 37(286): 290
ammonium magnesium phosphate (struvite) 56 7785-21-9 Uncles RF et al 1946
Solubility of magnesium ammonium phosphate hexahydrate N/A Industrial and engineering chemistry. 18(11): 699-702
ammonium magnesium phosphate (struvite) 56 7785-21-9 Webb KM and Ho GE 1992
Struvite (MgNH4PO4.6H2O) solubility and its application to a piggery effluent problem. N/A Water Sci Tech. 26(9-11): 2229- 2232
ammonium magnesium phosphate (struvite) 56 7785-21-9 Whitaker A 1968 The decomposition of struvite N/A Mineralogical magazine. 36: 820-824
ammonium magnesium phosphate (struvite) 56 7785-21-9 Wrigley TJ et al 1992
An improved computer model of struvite solution chemistry N/A Talanta. 39(12): 1597-1603
Monocalcium phosphate, Sodium metaphosphate, Calcium metaphosphate
21, 9 7758-23-8 Donoso-Torres 1958 Reactions of Metaphosphates in Soils No organism, tested in soilUniversity Microfilms an Arbor Mich PhD Thesis (No Mic 59-1192)
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-32
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
trisodium phosphate anhydrous, sodium acid pyrophosphate, tetrasodium pyrophosphate, tripotassium phosphate, monocalcium phosphate 4, 7, 14, 21 7601-54-9 Parent R. 1990 ABSTRACT: no title Rabbits j am coll toxicol 1: 4: 48-49
sodium phosphate' ? ? Earl JE and Whiteman HH 2010Evaluation of phosphate toxicity in Cope's Gray Treefrog (Hyla chrysoscelis) Tadpoles tadpoles Journal of Herpetology. 44(2): 201-208
? ? ? ? 1938 ? N/A Zh Obschch Khim. 8:1230-1231
mg phosphates ? ? Belopolskii AP et al 1950 ? (Title in Russian) N/A Zh Prikl Chim. 23: 823-36
STPP 0, (11?), 7 7758-29-4 Irani R.R. and Callis C.F. 1960
Metal complexing by phosphorus compounds. I. The thermodynamics of association of linear polyphosphates with calcium. J. Phys. Chem. 64:1398-1407
sodium tripolyphosphate, sodium pyrophosphate 0, ? 7758-29-4, ? Watanabe M 1974
The mechanism of the hydrolysis of condensed phosphates. I. The solvent effect on the hydrolysis of pyro- and tripolyphosphates N/A Bulletin of the Chemical society of Japan. 47(8): 2048-2050
sodium tripolyphosphate 0, 10 13573-18-7 Ishidate M. et al 1984primary mutagenicity screening of food additives currently used in Japan
bacteria salmonella (ames test) Fd. Chem. Toxic. 22(8): 623-636
STPP, SHMP, IMP 0, 10 ,11 7758-29-4 Harold FM 1966 Inorganic phosphates in biology:structure, metabolism and function, Bacteriological Reviews: 772-794.
STPP, sodium hexametaphosphate, tetrapotassium pyrophosphate 0, 10, 15 7758-29-4 Davis E.M. And Wilcomb M.J. 1967
Enzymatic degradation and assimilation of condensed phosphates by green algae algae water res. 1: 335-350
STPP, sodium hexametaphosphate, tetrapotassium pyrophosphate 0, 10, 15 7758-29-4 Davis E.M. And Wilcomb M.J. 1968
condensed phosphate degradation and assimilation by selected blue-green algae algae water res. 2: 311-324
STTP, SHMP, DSP 0, 10, 3 7758-29-4 Karb B. 1971 Effect of polyphosphates on chick embryos chicks Inst. Lanwirtsch. Zool. Bienenkd. 27(5): 237-251
STPP 0, 11, 10, 9, 7, 5 13573-18-7 Greenfield S 1975 First Edition, pp 1-202. n/aAnalytical chemistry of the condensed phosphates, Pergamon Press
sodium tripolyphosphate, dipotassium phosphate 0, 13 Berenson M.M. And Temple A.R. 1975
Detergent toxicity: effects on Esophageal and gastric mucosa cats clin. Toxicology 8(4): 399-404
STPP, dipotassium phosphate, tetrasodium pyrophosphate, 0, 13, 7,11, 8, 9 7758-29-4 Peters TV Jr and Rieman (III) Wm 1956
Analysis of Mixtures of the Condensed Phosphates by Ion-Exchange Chromatography; II. Mixtures of Ortho-, Pyro-, Tri-, Tetra-, Trimeta-. And Tetrametaphosphates and Graham’s Salt. N/A Analytical Chimica Acta, 14: 131-135
STPP, tripotassium phosphate, trisodium trimetaphosphate, trisodium hydrogen diphosphate 0, 14, 8, 6 7758-29-4
Beukenkamp J., Rieman W. and Lindenbaum S. 1954
Behavior of the condensed phosphates in anion-exchange chromatograpy. n/a Anal. Chem. 26, 3:505-512
STPP, tetrapotassium pyrophosphate 0, 15 7758-29-4 Hons FM, Steward WM and Hossner LR. 1986
Factor Interactions and their Influence on Hydrolysis of Condensed Phosphates in Soils Soil Soil Science: 408-416.
sodium tripolyphosphate, tetrapotassium pyrophosphate 0, 15 7758-29-4 Subbarao Y.V. Et al 1977
Kinetics of pyro- and tripolyphosphates hydrolyses in the presence of corn and soybean roots as determined by NMR spectography roots soil sci soc amer 41: 316-318
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-33
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium tripolyphosphate, tetrapotassium pyrophosphate 0, 15 7320-34-5 Weaver J.E. And Griffith J.F. 1969
induction of emesis by detergent ingredients and formulations dogs Toxicology and applied pharmacology 14: 214-220
sodium tripolyphosphate, monosodium phosphate, potassium dihydrogenphosphate, potassium tripolyphosphate 0, 2, 12, 16 7778-77-0 Matsuzaki H. et al 1999
Comparison of Various Phosphate Salts as the Dietary Phosphorus Source on Nephrocalcinosis and Kidney Function in Rats Rats J Nutr Sci Vitaminol 45: 595-608
sodium tripolyphosphate, monosodium phosphate, trisodium phosphate, potassium dihydrogenphosphate 0, 2, 4, 12 7558-80-7 Shibata M.A. Et al 1992
Inorganic alkalizers and acidifier under conditions of high urinary Na+ or K+ on cell proliferation and two-stage carcinogenesis in the rat bladder Rats Jpn. J. Cancer res. 83: 821-829
sodium tripolyphosphate, monosodium phosphate, trisodium phosphate, potassium dihydrogenphosphate 0, 2, 4, 12 7558-80-7 Shibata M.A. Et al 1991
comparative promoting activities of phosphate salts on rats two-stage bladder carcinogenesis under conditions of equivalent urinary Na+ or K+ levels Rats
teratogenesis, Carciogenesis and Mutagenesis 11: 305-316
STPP, monosodium phosphate, trisodium phosphate, sodium acid pyrophosphate 0, 2, 4, 5 7758-29-4 Bo X., Burnstock G. 1993
Triphosphate, the key structure of the ATP molecule responsible for interaction with P2x-purinoreceptors rats Gen. Pharmac. 24(3) 637-640
sodium tripolyphosphate, sodium orthophosphate, trisodium hydrogen diphosphate, trisodium trimetaphosphate 0, 2, 4, 5, 6, 8 7558-80-7 Blanchar R.W., Hossner L.R. 1969
Hydrolysis and Sorption Reactions of Orthophosphate, Pyrophosphate, Tripolyphosphate, and Trimetaphosphate Anions Added to an Elliot Soil soil soil sci soc amer proc 33: 141-144
sodium tripolyphosphate, sodium orthophosphate, trisodium hydrogen diphosphate, trisodium trimetaphosphate 0, 2, 4, 5, 6, 8 7558-80-7 Blanchar R.W., Hossner L.R. 1969
Hydrolysis and sorption of ortho-, pyro-, tripoly- and trimetaphosphate in 32 midwestern soils soil soil sci soc amer proc 33: 622-625
sodium tripolyphosphate, sodium orthophosphate, trisodium phosphate, tetrasodium pyrophosphate, sodium hexametaphosphate 0, 2, 4, 7, 10 7558-80-7
Bernhardt, A.M., Kunigelis S.C., Wilbur K.M. 1985
Effects of phosphates on shell growth and calcium carbonate crystal formation
Rangia cuneata (marine) and Helisoma duryi (freshwater) Aquatic Toxicology, 7, 1-13
STPP, MSP, SAPP 0, 2, 5 7758-29-4 Editha Karl-Krouper, Clayton F. Callis & Eli Seifter 1957
stability of condensed phosphates in very dilute solutions. n/a
Industrial and Engineering Chemistry. Vol. 49, no. 12, p2061-2062
STPP, MSP, SAPP, sodium tetrapolyphosphate 0, 2, 5, (4?) 7758-29-4 Tsuji S. et al 1986
The influence of rearing temperatures on the toxicity of various environmental pollutants for Killifish (Oryzias latipes) fish J Hyg Chem esei Kagaku 32(1): 46-53
STPP 0, 2, 5, 13 7758-29-4 Yamane A.N. Et al 1984Inhibitory effects of laundry detergents on the growth of freshwater algae algae Suishitsu Odaku Kenkyu 7(9):576-582
sodium tripolyphosphate, sodium orthophosphate, sodium acid pyrophosphate, trisodium trimetaphosphate, sodium metaphosphate 0, 2, 5, 8, 9 7558-80-7 Harris R.S. Et al 1967
the effects of phosphate structure on dental caries development in rats Rats J. D. Res. 46(1): 290-294
sodium tripolyphosphate, sodium phosphate, sodium acid pyrophosphate, graham's salt 0, 2, 5, 9, 11 231-449-2 Hahn f, Jacobi H, Seifen E 1958
Different Compatibility of orthophosphates and polyphosphates in chronic feeding tests? rats Arneimittel-forschung 8():286
sodium tripolyphosphate, sodium orthophosphate, trisodium hydrogen diphosphate, tetrasodium pyrophosphate, trisodium trimetaphosphate, sodium hexametaphosphate 0, 2, 6, 7, 8, 10 7558-80-7 Bell R.N. 1947 hydrolysis of dehydrated sodium phosphates soil ind eng chem 39: 136-140
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-34
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium tripolyphosphate, monosodium orthophosphate, tetrasodium pyrophoshpate, sodium hexametaphosphate 0, 2, 7, 9 7558-80-7 Kunigelis S.C. And Wilbur K.M. 1987
The effects of inorganic phosphates on trochopore larvae of the oyster crassostrea virginica oyster larvae int J invert repro and develop 12: 161-172
sodium tripolyphosphate, sodium orthophosphate, trisodium trimetaphosphate 0, 2, 8 7558-80-7 Muhlemann H.R. And Konig K.G. 1967
a comparative study of the cariostatic effect of dietary fluorides, orthophosphates and triphosphates in osborne-mendel rats Rats helv odontol acta 8(1): 56
STPP, MSP, DSP, TSP, SAPP, TSPP, SMP, SHMP, IMP, MKP, DKP, TKP, TKPP, KTPP, DAP, APP, MCP, DCP, TCP/HAP, CPP, DMP, TMP, MMP, PA
0, 2,3,4,5,7,9,10,11,12,13,14,15,16,19,20,21,22,24,26,29,30,31,46,48 N/A
INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY WORLD HEALTH ORGANIZATION TOXICOLOGICAL EVALUATION OF CERTAIN VETERINARY DRUG RESIDUES IN FOOD WHO FOOD ADDITIVES SERIES 17. 1982 Review: Toxicity
INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY WORLD HEALTH ORGANIZATION TOXICOLOGICAL EVALUATION OF CERTAIN VETERINARY DRUG RESIDUES IN FOOD WHO FOOD ADDITIVES SERIES 17.
STPP, MCP, DCP 0, 21, 22 7758-29-4
Integrated Pollution Prevention and Control: Reference Document on Best Available Techniques for the Manufacture of Large Volume Inorganic Chemicals - Solids and Others industry.
2006 - Aug
Risk Assessment guidance on prevention of pollution from manufacture and use ?
ECB.JRC ftp://ftp.jrc.es/pub/eippcb/doc/ [Draft BREF for LVIC-S products (2005)]
STPP, disodium phosphate, trisodium phosphate 0, 3, 4 7758-29-4 Smyth HF et al (1969) 1969
Range Finding Toxicity Data: List VII. Acute Toxicity and irritation data on about 200 compounds are presented, accumulated in a continuing program for screening potential commercial products. Rat American Industrial Hygiene Association Journal, 470-476
sodium tripolyphosphate, trisodium phosphate, sodium hexametaphosphate 0, 4, 10 7601-54-9 Marshall D.L., Jindal V. 1997
Microbiological Quality of Catfish Frames Treated with Selected Phosphates fish j. of food protection 60(9): 1081-1083
STPP, TSP, TKPP 0, 4, 15 7758-29-4 Lavoue et al 2003
Review.Technical, occupational health and environmental aspect of metal degreasing with aqueous cleaner. N/A Annual occupational hygiene.47.441-459
sodium tripolyphosphate, trisodium phosphate, tetrasodium pyrophosphate, trisodium trimetaphosphate, sodium hexametaphosphate 0, 4, 7, 8, 10 7785-84-4 Ivey J., Shaver K. 1977
Enzymic hydrolysis of polyphosphates in the gastrointestinal tract rats J. Agric. Food Chem. 25(1): 128-130
STPP, pyrophophosphoric acid, magnesium hydrogen orthophosphate, tricalcium phosphate, monocalcium phosphate, potassium metaphosphate, pentapotassium triphosphate, monopotassium phosphate, trisodium phosphate, disodium phosphate, monosodium phosphate
0, 45, 29, 24, 21, 17, 16, 12, 4, 3,
2 7758-29-4 Anon 1995
European Parliament and Council Directive No 95/2/EC of 20th February 1995 on food additives other than colours and sweeteners (OJ L 61, 18.3.1995, p.1). N/A (OJ L 61, 18.3.1995, p.1).
STPP, PA 0, 48 7758-29-4 Dr. Werner Kastner et Dr Peter GODE, Henkel KGaA 1983
Toxicity via oral, sub-cutaneous, cutaneous, intraperitoneal routes rats, mice, rabbits Toxicite et ecotoxicite des produits de traitement des eaux
STPP, phosphoric acid 0, 48 7758-29-4 Ramel C. and Magnusson J. 1979 chemical induction of nondisjunction in Drosophilia drosophila melanogaster Environmental Health perspective 31: 59-66
sodium tripolyphosphate, Sodium pyrophosphate 0, 5 7758-16-9 Chang C. and Racz G.J. 1977
Effects of temperature and phosphate concentration on rate of sodium pyrophosphate and STPP hydrolysis in soil soils can J soil science 57: 271-278
sodium tripolyphosphate, sodium acid pyrophosphate 0, 5 7758-16-9 Clesceri N.L. And Lee G.F. 1965
Hydrolysis of condensed phosphates – II: sterile environment water int. J. air Wat. Poll. 9: 743-751
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-35
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium tripolyphosphate, Sodium pyrophosphate 0, 5 7758-16-9 Crowther J.P. And Westman A.E.R. 1954 the hydrolysis of the condensed phosphates water can j chem 32: 42-48
STPP, SAPP 0, 5 7758-29-4 Gosselin RE and Megirian R 1955The Influence of Chain Length on The Metabolic Fate of Condensed Phosphates Rat and Rabbit J Pharm Exp.Ther. 114: 402-407
STPP, SAPP 0, 5 7758-29-4 Heinke GW 1969Hydrolysis of condensed phosphates in Great Lakes Waters water
Internat. Assoc. Great Lakes Res., Proc. 12th Conf:766-773
STPP, SAPP 0, 5 7758-29-4 Smith M.J. 1959Independence in hydrolysis of condensed phosphates water Can. J. Chem., 37: 1115-1116
STPP, SAPP 0, 5 7758-29-4 Gosselin RE et al
1984 Clinical toxicity of commerical products Clinical Toxicology of Commercial Products. 5th Ed.11-121
sodium tripolyphosphate, sodium pyrophosphate 0, 5 7758-16-9 Savant N.K. And Racz G.J. 1972
hydrolysis of sodium pyrophosphate and STPP by plant roots seeds soil science 113(1): 18-22
sodium tripolyphosphate, sodium acid pyrophosphate, sodium hexametaphosphate, calcium trimetaphosphate 0, 5, 10, n/a 7758-29-4 Seward R.A. Et al 1986 Heat-Sensitization of Salmonella by Polyphosphates bacteria J. of food science 51(2): 471-473
sodium tripolyphosphate, sodium pyrophosphate, tripotassium phosphate 0, 5, 14 7758-16-9 Blanchar R.W., riego D. 1976
tripolyphosphate and pyrophosphate hydrolysis in sediments sediments soil sci soc amer proc 40: 225-229
STPP, sodium acid pyrophosphate, tetrasodium pyrophosphate, monopotassium phosphate 0, 5, 7 , 12 7758-29-4 Clesceri N.L. And Lee G.F. 1965
Hydrolysis of condensed phosphates – I: non-sterile environment water int. J. air Wat. Poll. 9: 723-742
Various 0, 5, 7, 8, 19, 18, 16, 46, 15, 14,
13, 12, 17, 20, 4, 3, 2 Various Gard 2001 Phosphoric Acids and Phosphates. n/a
Kirk-Othmer Encyclopaedia of Chemical Technology.phosphoric acid and phosphates Kirk-Othmar encyclopedia 2001
sodium tripolyphosphate, sodium acid pyrophosphate, tetrasodium pyrophosphate, trisodium trimetaphosphate, sodium metaphosphate, sodium hexametaphosphate, CarbP
0, 5, 7, 8, 9, 10, 51 7758-16-9 Zipf. K.. 1957
ABSTRACT: Studies on the toxicology of polyphosphates Mouse Arzneimittel 7(7) : 446-447
sodium tripolyphosphate, sodium acidpyrophosphate, tetrasodium pyrophosphate, sodium polyphosphate glassy 0, 5, 7, 9 7758-16-9 Akhtar S. et al 2008
Inhibitory effects of polyphosphates on Clostridium perfringens growth, sporulation and spore outgrowth fungus Food Microbiology 25: 802– 808
sodium tripolyphosphate, sodium acidpyrophosphate, tetrasodium pyrophosphate, sodium polyphosphate glassy 0, 5, 7, 9 7758-16-9 Molins R.A. Et al 1985
Effect of Poly- and Pyrophosphates on the natural Bacteria Flora and inoculated Clostridium sporogenes PA 3679 in cooked packaged Bratwurst bacteria J of foof science 50: 876-880
STPP, SAPP, STMP, SHMP 0, 5, 8, 10 7758-29-4 Green J 1950Reversion of molecularly dehydrated sodium phosphates. n/a Industrial & Engineering Chemistry, 42 (8): 1542-1546
STPP0, 5, 8, 10, 11
7758-29-4 Chadiot P and Lafuma J 1962Acute Toxicity: Therapeutic Chelatants of Use in Nuclear Industry. mice
Review of Epidemiological Social Medicine and Public Health. (Toxicité Aiguë Des Chélatant Thérapeutiques Utilisables Dans L’Industrie Nucléaire. Revue d’Epidemiologie Medecine Sociale et Santé Publique.
STPP, sodium acid pyrophosphate, trisodium trimetaphosphate, sodium metaphosphate / hexametaphosphate 0, 5, 8, 9/10 7758-29-4 Gosselin R.E. Et al 1952
metabolic acidosis and hypocalcemia as toxic manifestations of polymeric phosphates rats
Journal of Pharmacology and Experimental Therapeutics. 117-127.
sodium tripolyphosphate, sodium pyrophosphate, sodium metaphosphate 0, 5, 9 7758-16-9 Hahn f, Jacobi h, Rummel W. 1956
ABSTRACT: chronic feeding experiments with polyphosphates Rats Die Naturwissenchaften 43(23): 539-540
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-36
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
STPP, TSPP 0, 7 7758-29-4Van Wazer JR, Griffith EJ and McCullough JF 1955
Structure and properties of the condensed phosphates. VII. Hydrolytic degradation of pyro- and tripolyphosphate N/A J. Am. Chem. Soc., 77: 287-291
sodium tripolyphosphate, sodium pyrophosphate, sodium trimetaphosphate, sodium tetrametaphosphate 0, 7(or 5), 8
7758-29-4, 7722-88-5, 7785-84-4 Watanable M, Sato S and Saito H 1976
The mechanism of the hydrolysis of condensed phosphates. IV. The hydrolysis of pyro-, tripoly-, trimeta- and tetrametaphosphates in aqueous organic solvents N/A
Bulletin of the Chemical Society of Japan. 49(9): 2474-2478
STPP 0, 7, 11, 28 7758-29-4 Irani R.R. and Morgenthaler W.W. 1963 Iron sequestration by polyphosphates. n/a J. Am. Oil Chem. Soc. 40:283-285
STPP, TSPP, STMP, sodium acid pyrophosphate, disodium phosphate 0, 7, 8, 5, 3 7758-29-4 Torres-Dorante L.O. Et al 2005
Hydrolysis rates of inorganic polyphosphates in aqueous solution as well as in soils and effects on P availability water and soil J plant nutr soil sci 168: 352-358
sodium tripolyphosphate, tetrasodium diphosphate, sodium polyphosphate (65% P2O5) 0, 7, 9 7722-88-5 Fingerhut F., Ruf F., Lang K. 1965 resorption of the polyphosphates rats klin wochensch 43: 956-957
sodium tripolyphosphate, Tetrasodium pyrophosphate, Graham's salt, sodium pentapolyphosphate 0, 7, 9, n/a 231-767-1 Schreier K. and Noller H.G. 1955 Metabolism of different activated polyphosphates Rats Arch. Exper. Path. U Pharmakol. 227: 199-209STPP, trisodium trimetaphosphate 0, 8 7758-29-4 Dick R.P. And Tabatabai M.A. 1986 Hydrolysis of polyphosphates by corn roots corn Plant and soil 94: 247-256
sodium tripolyphosphate, sodium trimetaphosphate 0, 8 7785-84-4 Gosselin R.E. Et al 1952 the hydrolysis and excretion of polymeric phosphate Rats ??: 180-192
sodium tripolyphosphate, sodium trimetaphosphate 0, 8 7785-84-4 Kornberg S.R. 1955
tripolyphosphate and trimetaphosphate in yeast ABSTRACTs yeast Jourma; of biological cheistry
STPP, STMP, TSP, sodium dihydrogen orthophosphate, sodium phosphate-glass, sodium ultraphosphate 0, 8, 4, 2, 9, n/a 7758-29-4 El-Reweiny F.M. et al 1976
effects of condensed phosphates on plant growth and phosphorus uptake grass Plant and soil 44: 1-14
sodium tripolyphosphate, sodium metaphosphate, sodium hexametaphosphate 0, 9, 10 68915-31-1 Cardenas J. et al 1960 action of phosphates on experimental tumors Rats and mice Acta pharmacol. Et toxicol. 17: 157-160
sodium tripolyphosphate, sodium metaphosphate, sodium hexametaphopshate 0, 9, 10 68915-31-1 Perova N.M.and Sergeev A.N. 1973
experimental substantiation of hygienic standardization of sodium hexametaphopshate and tripolyphosphate in drinking water water gisaaa gigiena i sanitariya 38(9): 19-22
STPP, SMP, SAPP, STMP 0, 9, 5, 8 7758-29-4 Dick R.P. And Tabatabai M.A. 1986 Hydrolysis of polyphosphates in soil soil soil science 142(3): 132-140
STPP, SMP, SAPP, STMP 0, 9, 5, 8 7758-29-4 Dick R.P. And Tabatabai M.A. 1987Factors affecting hydrolysis of polyphosphates in soils soils soil science 143(2): 97-104
0,2,3,4,5,7,10, calcium acid phosphate
0,2,3,4,5,7,10, calcium acid phosphate 7758-29-4 Tompkin RB 1983 Microbial effects of phosphates microbes Journal of food safety. 6:13-27
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-37
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
STPP, MSP, DSP, TSP, SAPP, TSPP, MKP, DKP, TKP, TKPP, KTPP, DAP, APP, MCP, DCP, TCP, CPP, DMP, TMP, MMP, MALP, BOP, SFP, PA, PPA, PyroPA
0,2,3,4,5,7,12,13,14,15,16,18,19,20,21,22,24,26,29,30,31,39,44,47
,48,49,50 N/A Schrödter K et al 2007 physiochemical properties (pg 23) n/aUllmann's Encyclopedia of Industrial Chemistry, Author's Edition Phosphoric acid and Phosphates
STPP and tetrasodium pyrophosphate 0,7 7758-29-4 Elliot P, Straka RP and Garibaldi JA 1964
Polyphosphate inhibition of growth of Pseudomonads from poultry meat. Bacteria Applied microbiology.12(6):517-522
sodium hexametaphosphate, sodium tripolyphosphate, sodium tetraphosphate and terasodium pyrophosphate. 10, 0, 7 10124-96-8
Post FJ, Coblentz WS, Chou TW & Salunkhe DK 1968
Influence of phosphate compunds on certain fungi and their preservative effects on fresh cherry fruit (Prunus cerasus, L.) fungi Applied microbiology. 16(1): 138-142
sodium hexqametaphosphate, monopotassium phosphate, dipotassium phosphate, 10, 12, 13 68915-31-1
Steinhardt Bour NJ et al
1984
Effect of level and form of phosphorous and level of calcium intake on Zinc, Iron and Copper bioavailability in man. man Nutrition Research, 4:371-379
sodium hexametaphosphate, dibasic potassium phosphate 10, 13 68915-31-1
Dymsza H.A., Reussner G.Jr, Thiessen Jr 1959
effect of normal and high Intakes of Orthophosphates and metaphosphates in Rats rats j. Nutrition 69: 419-428
sodium hexametaphosphate, sodium acid pyrophosphate, disodium phosphate 10, 5, 3 10124-56-8
K. G. König, Th. M. Marthaler & H. R. Mühlemann
1961 rat
sodium hexametaphosphate, sodium acid pyrophosphate, trisodium phosphate, disodium phosphate, STPP 10, 5, 4, 3, 0 10124-56-9
Batra S.C.
1965The ionisation behaviour of some poly (meta) phosphates used in food products. n/a J. Food Sci. 30:441-444
sodium hexametaphosphate, tetrasodium pyrophosphate, sodium acid pyrophosphate, disodium phosphate 10, 7, 5, 3 10124-56-10
FDA - Dietary Supplements [Reserved] Subpart G - Sequestrants, 461.
Food and Drug Administration, HHS Subpart F
Sodium hexametaphosphate and calcium hexametaphosphate 10, 9 10124-56-11 Tibdall C.S. et al 1952
ABSTRACT: mechanisms responsible for the acute toxicity of a phosphate glass Rats fed proc 11(1): 162
sodium metaphosphate insoluble, sodium hexametaphosphate 11, 10 10361-03-2 Terrey H. 1937
Inorganic Chemistry 1. The metaphosphates and polyphosphates of sodium. n/a Ann Reports Progr Chem, 34 (SUPPL: ref topley): 115-122
sodium metaphosphate insoluble, sodium hexametaphosphate 11, 10 10361-03-2 Van Wazer J R 1950
Structure and properties of the condensed phosphates. III. Solubility fractionation and other solubility studies. J Amer. Chem. Soc. 72: 647 - 655.
sodium metaphosphate insoluble, sodium hexametaphosphate, trisodium trimetaphosphate 11, 10, 8 10361-03-2
CIR Epxert Panel (2001), Final Report on the Safety Assessment of Sodium Metaphosphate, Sodium Trimetaphosphate and Sodium Hexametaphosphate, International Journal of Toxicology, 20(Suppl. 3):75-89;
sodium metaphosphate insoluble, monosodium phosphate, disodium phosphate, 11, 2, 3 10361-03-2
Zemel MB and Bidari M 1983
Zinc, Iron and Copper Availability as Affected by Orthophosphates, Polyphosphates and Calcium. rat Journal of Food Science, 48: 567-571
monopotassium phosphate, STPP 12, 0 7778-77-0 Samanidou V. 1990mobilisation of heavy metals from river sediments of northern Greece by complexing agents rivers Water, air and soil pollution 52: 217-225
potassium dihydrogenphosphate, dipotassium hydrogenorthophosphate 12, 13 7778-77-0 Sirova MA and Loeb LA 1976
Infidelity of DNA synthesis in vitro: screening for potential metal mutagens or carcinogens Science. 194(4272): 1432-1436
monopotassium phosphate, dipotassium phosphate 12, 13 7778-77-0 Torriani A 1960
Influence of inorganic phosphates on enzyme formation in E.coli Bacteria Biochem. Biophys. Acta, 38:460-479
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-38
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monopotassium phosphate, dipotassium phosphate, monosodium phosphate, disodium phosphate 12, 13, 2, 3 7778-77-0 Kalashnikova NA & Rodenvich 1970
Effect of phosphates on phophatase synthesis by the culture Aspergillus awamori strain 22 n./a Prikl Biokhim Mikrobiol. 6: 516-519
potassium dihydrogenphosphate (KH2PO4), potassium tripolyphosphate 12, 16 7778-77-0 Matsuzaki H. et al 2001
Greater effect of dietary potassium tripolyphosphate than of potassium dihydrogenophosphate on the nephrocalcinosis and proximal tubular function in female rats from the intake of a high-phosphorus diet rats Biosci. Biotechnol. Biochem 65(4): 928-934
Potassium dihydrogen orthophosphate, Sodium and potassium pyrophosphate, Potassium triphosphate, Potassium trimetaphosphate
12, 16 7778-77-0 Miller G and Porter AS 1967Activity Coefficients of Some Polyphosphates in Aqueous Solution. N/A Trans Faraday Soc, 63: 335-340
monopotassium phosphate, monoammonium phosphate 12, 18
7778-77-0, 7726-86-1 Janecke E 1927
Das quaternare system K2O-NH3-P2O5-H2O bei 0° und 25° N/A Z Physik Chem. 127:71-92
potassium dihydrogen orthophosphate, disodium dihydrogenorthophosphate 12, 2 7778-77-0
Thilo E.
1956 Zur Chemie der kondensierten Phosphate. Chem. Technol., 8:251-270
monopotassium phosphate , monosodium phosphate 12, 2 7778-77-0
Silverberg SJ et al
1986
The Effect of Oral Phosphate Administration on Major Indices of Skeletal Metabolism in Normal Subjects. human Journal of Bone and Mineral Research, 1(4): 383-388
monopotassium phosphate , monosodium phosphate 12, 2 7778-77-0
Griffith EJ, 1959
A nomograph for the hydrolytic degradation of pyrophosphates and tripolyphosphates, Industrial and Engineering Chemistry, 51: 240.
potassium dihydrogen phosphate and disodium hydrogen phosphate 12, 2 7778-77-0 Jowsey J and Balasubramaniam P 1972
Effect of phosphate supplements on soft-tissue calcification and bone turnover. Clinical Science. 42: 289-299
monopotassium phosphate, disodium pyrophosphate, sodium tripolyphosphate, (NH4)6P4O13 (Hexa-ammonium tetraphosphate), Sodium phosphate Glass Type, 5, 15, 25, 35, 45, 65, 75
12, 2, 0 7778-77-0 Mussig-Zufica VM and Jekel M 1992
Methods for Differentiated Determination of Orthophsophate, Condensed Phosphates and Polyphosphate N/A Z Wasser-Abwasser-Forsch, 25: 353-356
potasium phosphate, dicalcium phosphate 12, 22 7757-93-9 Pond W.G. And Walker E.F. 1975
Effect of dietary Ca and Cd level of pregnant rats on reproduction and on Dam and progeny tissue Mineral concentration (38606) Rats
Proceedings of the soc. For exp. Biology and medicine 148: 665-668
monopotassium phosphate, dicalcium phosphate 12, 22 7778-77-0
Pond WG, Walker EF and Kirtland D 1978
effect of dietary Ca and P levels from 40 to 100 kg bodyweight on weight gain and soft tissue mineral concentrations. Pigs Journal of animal science. 46(3): 686-691
dipotassium phosphate, sodium acid pyrophosphate 12, 5 7757-93-9
Garen A and Levinthal C
1960A Fine-Structure Genetic and Chemical Study of the Enzyme Alkaline Phosphatase of E.coli. E.coli unknown
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-39
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Dipotassium phosphate, monocalcium phosphate, dicalcium phosphate, copper (II)-hydroxyphosphate, tetrasodium pyrophosphate 13, 21, 22, 38, 7
7758-11-4, 7758-23-8, 7757-93-9,
12158-74-6, 7722-88-5 Duc-Maugé C 1959
Structure de l'ion PO43- dans l'anhydride phosphorique et les phosphates métalliques N/A Bull Soc Chem France: 1032-1042
dipotassium phosphate, disodium phosphate 13, 3 7758-11-4
Schneider P, Ober KM and Uerberberg H
1981
Contribution to the phosphate-induced nephropathy in the dog. Comparative light and electron microscopic investigations on the proximal tubule after oral application of K2HPO4, Na2HPO4, KCl and NaCl. Experimental pathology 19: 53-65
dipotassium phosphate, disodium phosphate 13, 3 7758-11-4
Lehman JT
1976
Ecological and nutritional studies on Dinobryon Ehrenb.: Seasonal periodicity and the phosphate toxicity problem. dinobryon Limnology and Oceanography, 21(5): 646-658
TKP, MSP, SAPP 14, 2, 5 7778-53-2 Wallen IE et al 1957Stream Pollution, Toxicity to Gambusia affinis of certain pure chemmicals in turbid water. fish Sewage and industrial wastes, 29(6): 695-711
potassium pyrophosphate, pyrophosphoric acid 15, 50 7320-34-5 Gilliam J.W. 1970
Hydrolysis and uptake of pyrophosphate by plant roots plants soil sci soc amer proc 34: 83-86
monoammonium phosphate, tripotassium phosphate, disodium phosphate, monosodium phosphate 18, 14, 3, 2 7722-76-1 JECFA 59th 2002 Phosphoric acid prepared at the 59th JECFA n/a
Ammonium dihydrogen phosphate prepared at the 27th JECFA (1983) published in 1983 and 1992. Revised at the 59th JECFA (2002).
monoammonium phosphate, diammonium phosphate 18, 19
7722-76-1, 7783-28-0 Ross WH, Mertz AR & Jacob KD 1929
Preparation and properties of the ammonium phosphates n/a Industrial and Engieneering chemistry. 21(3): 286-288
monoammonium phosphate, disodium phosphate 18, 2 7722-76-1
Fazekas IG1954
Fazekas IG (1954) Vergößerung der Nebenschilddrüsen durch einfach acidotische Verbindungen. Enlargement of parathyroid glands by simple acidic compounds.? Virchows Archiv 324: 531-542
Various
19, 18, 16, 15, 14, 13, [13, 11, 10, 7, 5, 3, 2],
12, 10, 5 8, 5, 4, 3, 2 various
Furia T E1972 Handbook of Food Additives N/A Handbook of food additives.CRC
diammonium orthophosphate, ammonium polyphosphate 19, 20
7783-28-0, 14728-39-3 Subbarao Y.V. And Ellis R. 1975
reaction products of polyphosphates and orthophosphates with soils and influence on uptake of phosphorus by plants soil soil sci soc amer proc. 39: 1085-1088
diammonium phosphate, ammonium polyphosphate 19, 20
7783-28-0, 14728-39-3 Johnson W.W., Sanders H.O. 1977
Chemical forest fire retardants: acute toxicity to five freshwater fishes and a Scud fish and scud us fish wildlife serv tech pap 91: 1-8
diammonium orthophosphate, ammonium polyphosphate 19, 20
7783-28-0, 14728-39-3 Khasawneh F.E. Et al 1974
reactions of ammonium ortho- and polyphosphate fertilizer in soil: I Mobility of Phosphorus soils soil sci soc amer proc 38: 446-451
diammonium orthophosphate, ammonium polyphosphate 19, 20
7783-28-0, 14728-39-3 Khasawneh F.E. Et al 1979
reactions of ammonium ortho- and polyphosphate fertilizer in soil: II Hydrolysis and reactions with soil soil soil sci soc amer proc 43: 52-58
diammonium orthophosphate, ammonium polyphosphate 19, 20
7783-28-0, 14728-39-3
Sutton C.D., Gunary D. and Larsen S.
1966Pyrophosphate as a source of phosphorus for plants II. Hydrolysis and initial uptake by a barley crop. Soil Sci., 101(): 199-204
sodium phosphate, lead phosphate 2 (?) 7558-80-7 Gray I and Greenfield I 1938 Lead poisoning. Newer concepts in treatment. human New York State Journal of Medicine. 38(20): 1313-1319
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-40
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium dihydrogen phosphate 2, 7558-80-7 Ritskes-Hoitinga J., Lemmens A.G. And Beynen A.C. 1989 Nutrition and kidney calcification in rats Rats Laboratory animals 23: 313-318
Anhydrous sodium dihydrogen orthophosphate NaH2PO4 2, (3) 7558-80-7 Brewer H.E. Et al 1970
A clinical study concerning the anticariogenic effects of NaH2PO4-enriched breakfast cereals in institutionalized subjects: results after two years human J. Amer. Dent. Assoc. 80: 121-124
monosodium phosphate (MSP), sodium tripolyphosphate (STPP) 2, 0 7558-80-7
Lorenz B et al
1994
Purification and Characterization of an Exopolyphosphatase from Saccharomyces cerevisiae. n/a The Journal of Biological Chemistry 269(35): 22198-22204.
sodium phosphate, sodium hexametaphosphate, monosodium phosphate 2, 10, 8 7558-80-7 Borenstein M.K. And Schwartz C. 1948
The effect of the complex-forming amorphous sodium phosphates on the calcium retention of rats Rats J Nutr. 36: 681-694
Anhydrous sodium dihydrogen orthophosphate NaH2PO4, monopotassium phosphate, dipotassium phosphate 2, 12, 13 7558-80-7 Handelman S.L., Kreinces G.H. 1972
Effect of phosphate and pH on Streptococcus mutans acid production and growth bacteria J. Dent. Res. 52(4): 651-657
monosodium phosphate, monoammonium phosphate 2, 18 7558-80-7 Reinhardt TA & Conrad HR 1980
Mode of Action of Pharmacological Doses of Cholecalciferol during Parturient Hypocalcemla In Dairy Cow. cows J Nutr. 110:1589-1596
Sodium dihydrogen phosphate, Calcium sodium magnesium phosphate, Calcium hydrogenorthophosphate/Calcium dihydrogenorthophosphate, Calcium bis(dihydrogenorthophosphate), Calcium-sodium-phosphate
2, 21, 22,23 7558-80-7 Wendt P et al 2004
Investigations on the availability of inorganic phosphate from different sources with growing white Pekin ducks Pekin duck Poult. Sci. (2004) 83:1572-1579.
monosodium phosphate, disodium phosphate 2, 3 7558-80-7 Abelin. J. Kobori. B 1927 effect of sodium phosphate on basal metabolism rats Biochem Z., 180():211-217
sodium phosphate monobasic, sodium phosphate dibasic 2, 3 7558-80-7 Haut L.L. Et al 1980 Renal toxicity of phosphate in rats rats Kidney international 17: 722-731
monosodium phosphate (75% of the mixture), disodium phosphate (25% of mixture) 2, 3 7558-80-7 Rowe N.H. Et al 1974
ABSTRACT: The clinical effect of phosphate-enriched breakfast cereals on dental care incidence in adolscent children human J. D. Res spec issue, 53: 605
sodium dihydrogen phosphate, disodium phosphate, trisodium trimetaphosphate 2, 3, 0 7558-80-7 Peterson J.K. 1969
ABSTRACT: North Dakota field test of cariostatic effect of 1% sodium dihydrogen phosphate and disodium hydrogen phosphate added to presweetened breakfast cereals human J. D. Res. 1308
monosodium phosphate, disodium phosphate, calcium phosphate 2, 3, 21 7558-80-7 Goodman and Gliman 1996 The Pharmacological basis of therapeutics
The Pharmacological basis of therapeutics. 9th Edn. Goodman & Gilmans
sodium dihydrogen orthophosphate, disodium phosphate, trisodium phosphate, phosphoric acid 2, 3, 4, 48 7558-80-7 MacKay E.M. And Olivier J. 1935
renal damage following the ingestion of a diet containing an excess of inorganic phosphate rats j. exp. Med. 61: 319
sodium dihydrogenorthophosphate, disodium hydrogenorthophosphate, trisodium orthophosphate, tetrasodium pyrophosphate, sodium tripolyphosphate, sodium polyphosphate 2, 3, 4, 7, 0, 9
7558-80-7, 7558-79-4, 7601-54-9, 7722-
88-5 7758-29-4, 68915-31-1, Nakagaki M, Ohashi S and Minato F 1963
Viscometric studies of solutions of sodium phosphates, graham salts and vanadium-containing graham salt N/A Viscosities of sodium phosphates and grahams salts. 36(3)
monosodium phosphate, disodium phosphate, phosphoric acid 2, 3, 48 7558-80-7 Binger C 1918
Toxicity of phosphates, in relation to blood calcium and tetany dog
Journal of Pharmacology and Experimental Therapeutics. 10:105
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-41
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Complex sodium phosphate and trisodium phosphate included in the light duty liquid cleaner and granular laundry detergent 2, 4 7558-80-7 Booman KA et al 1988
In vitro methods for estimating eye irritancy of cleaning products phase I: Preliminary assessment rabbit eye N/A
monosodium phosphate, trisodium phosphate
2, 4 7558-80-7 Osterburg RE 1977Potential biological hazards of commercially available cleansers for dentures. N/A
Journal of Toxicology and Environmental Health, 3: 969-977
disodium phosphate, sodium pyrophosphate 2, 5 7558-80-7 Datta P.K. Et al 1962 Biological effects of food additives rats Sci. Food Agric. 13: 556-566
sodium dihydrogenorthophosphate, sodium acid pyrophosphate 2, 5
7558-80-7, 7758-16-9 Morley GW 1953 The system H2O-NaPO3 N/A J Am Chem Soc 75:5794-5797
sodium phosphate, sodium acid pyrophosphate, graham's salt 2, 5, 9, 11 231-449-2 Hahn F, Seifen E 1959
Further tests on the tolerability of phosphates following chronic application rats Arneimittel-forschung 9():501
monosodium phosphate, sodium acid pyrophosphate, tetrasodium pyrophosphate, sodium hexametaphosphate and sodium tripolyphosphate 2, 5, 7 7558-80-7
Knabel SJ, Walker HW & Hartman PA 1991
Inhibition of Asperigillus flavus and selected Gram-positive bacteria by chelation of essential metal cations by polyphosphates. Bacteria JOURNAL OF FOOD PROTECTION, 54
sodium phosphate monobasic, sodium acid pyrophosphate, tetrasodium pyrophosphate, sodium polyphosphate, sodium metaphosphate, potassium metaphosphate, calcium phosphate, monobasic, calcium phosphate dibasic, ferric pyrophosphate, sodium monoflurophosphate
2, 5, 7, 9, 10, 17, 21, 22, 28, 47 7558-80-7 Ishidate M, Sofuni T. 1988 chromosomal aberration test in vitro In vitro Data book of chromosomal aberration test in vitro
sodium phosphate, monobasic, sodium acid pyrophosphate, potassium metaphosphate, sodium metaphosphate (different CAS number to that considered by IPC) 2, 5, n/a, 17 7558-80-7 Ishidate M. et al 1984
primary mutagenicity screening of food additives currently used in Japan
bacteria salmonella (ames test) Fd. Chem. Toxic. 22(8): 623-636
sodium phosphate, monobasic, sodium acid pyrophosphate, potassium metaphosphate, sodium metaphosphate (different CAS number to that considered by IPC) 2, 5, n/a, 17 7558-80-7 Ishidate M. et al 1984
primary mutagenicity screening of food additives currently used in Japan hamster fibroblasts Fd. Chem. Toxic. 22(8): 623-636
sodium phosphate monobasic, sodium acid pyrophosphate, tetrasodium pyrophosphate, sodium polyphosphate, potassium metaphosphate, ferric pyrophosphate 2, 6, 7, 9, 17, 28 7558-80-8 Ishidate M. 1991 test on chemicals in bacteria bacteria data book of mutagenicity
disodium hydrogenphosphate, tetrasodiumpyrophosphate, sodium tripolyphosphate, grahams salt 2, 7, 0, 11
7558-79-4, 7722-88-5, 7758-29-4 Feldheim W and Hesselbach C 1985
Untersuchungen zum calcium- und phosphorstoffwechsel beim menschen. Minature pig Art Ernahr. 10. 30-33
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-42
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monosodium phosphate, tetrasodium pyrophosphate, sodium hexametaphosphate, dipotassium phosphate, monocalcium phosphate, tricalcium phosphate
2, 7, 10, 12, 21, 24 7778-77-0 Verret J. et al 1980
Toxicity and Teratogenicity of 80 food additives chemicals in the developing chicken embryo chicken embryo Toxicology and applied pharmacology 56: 265-273
sodium orthophosphate, sodium metaphosphate 2, 9 7558-80-7 Saxton J.A. And Ellis G.H. 1941
ABSTRACT: effects on long-continued ingestion of sodium phosphate upon the parathyroid, kidneys and bones of mature rats Rats am j path 17: 590
monosodium phosphate, sodium hexametaphosphate 2, 9 68915-31-1 Tria E. 1950
hexametaphosphate, anticoagulant actin in vivo and in vitro dog boll soc ital biol sper 26 (chem abstr 45-8643): 113
monosodium phosphate, disodium phosphate, sodium tripolyphosphate, dicalcium phosphate 2,3,0,22 7558-80-7
Bushman DH, Emerick RJ & Embry LB 1965
Incidence of urinary calculi in sheep as affected by various dietary phosphates sheep J Anim Sci 1965. 24:671-675.
monosodium phosphate, disodium phosphate, trisodium phosphate 2,3,4 7558-80-7
Anderson BG 1946
The toxicity thresholds of various sodium salts determined by the use of Daphnia magna. daphnia magna. Sewage works Journal. 18(1): 82-87
monosodium phosphate, disodium phosphate, trisodium phosphate, tetrasodium pyrophosphate 2,3,4,7 Starkenstein E 1911 Ionenwirkkung der Phosphorsauren ? Biochem Z. xxxii: 243-264ammonium polyphosphate, monoammonium phosphate, diammonium phosphate 20, 18, 19, 68333-79-9
SIDS intial assessment profile.SIAM.24.
2007
SIDS intial assessment profile.SIAM.24.
rats, fish
US ICCA SIAM phosphates 4-2007.pdf
monocalcium phosphate (hydrate), dipotassium phosphate 21, 12 7758-23-8 Da silva L.R.C. Et al 1991
effects of phosphate sources on the mycelial growth of gigaspora gigantea in vitro fungus Revista Brasileira de Ciencia do solo 156: 169-172
monocalcium phosphate, dipotassium hydrogenorthophosphate, sodium dihydrogenorthophosphate monohydrate 21, 12, 2 7758-23-8
Krook L, Lutwak L, Hnrikson P, Kallfelz F, Hirsch C, Romanus B, Belanger LF, Marier JR and Shefft BE 1971
Reversibility of Nutritional Osteoporosis: Physicochemical Data on Bones from an Experimental Study in Dogs dogs The journal of nutrition. 101:233-246
monocalcium phosphate, diammonium phosphate, sodium metaphosphate insoluble, sodium hexametaphosphate, sodium polyphosphate 21, 19, 11, 10, 9, 7758-23-8
46th JECFA.
1996 JECFA N/APublished in 1967, 1992 and 1996. Revised at the 26th JECFA 1982.
dibasic calcium phosphate dihydrate, mono-dicalcium phosphates, di-monocalcium phosphates. 21, 22 7758-23-8 Sullivan TW 1992
Correlation of biological value of feed phosphates with their solubility in water, dilute hydrogen chloride, dilute citric acid and neutral ammonium citrate. turkey Poultry Science. 71:2065-2075
monocalcium phosphate, dicalcium phosphate 21, 22 7758-23-8 Sullivan TW et al 1989
Evaluation of new and established feed phosphates in turkey starter diets turkey Poultry Science. 68(1):143
monocalcium hposphate, dicalcium phosphate 21, 22 7758-23-8 Waibel PE et al 1984
bioavailability of phosphorous in commercial phosphate supplements for turkeys. turkey Poultry Science. 63:730-737
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-43
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monocalcium phosphate, dicalcium phosphate 21, 22 7558-23-8
Knowlton KF, Herbin JH, Meister-Weisbarth MA and Wark WA 2001
Nitrogen and Phosphorus Partitioning in Lactating Holstein Cows Fed Different Sources of Dietary Protein and Phosphorus cows J. Dairy Sci. 84:1210–1217
monocalcium phosphate, dicalcium phosphate 21, 22 7758-23-8 Hepher B & Sandbank S 1984
The effects of phosphorus supplementation to common carp diets on fish growth. fish Aquaculture, 36:323-332
monocalcium phosphate, dicalcium phosphate 21, 22 7758-23-8 Keshavarez K 1994
Laying hens respond differently to high dietary levels of phosphorus in monobasic and dibasic calcium phosphate. hens Poultry Science. 73: 687-703
Calcium bis(dihydrogenorthophosphate), Calcium hydrogenorthophosphate, ammonium dihydrogenorthophosphate, Thermomagnesium phosphate
21, 22, 18 7758-23-8 Lima FR et al 1999Laboratory evaluations of feed-grade and agricultural-grade phosphates N/A Poult. Sci. 78(12):1717-1728
calcium phosphate monobasic, calcium phosphate dibasic, sodium phosphate monobasic. 21, 22, 2 7758-23-8 Richardson NL et al 1985
Influence of dietary calcium, phosphorous, zinc and sodium phytate level on cateract incidence, growth and histopathology in juvenile Chinook salmon (Oncorhynchus tshawytscha). fish American Institute of Nutrition. 553-567
Monocalcium phosphate, Dicalcium phosphate, Beta-tricalcium phosphate, Tricalcium phosphate
21, 22, 23, 24 7758-23-8 Gillis MB et al 1952Studies on the availability of calcium orthophosphate to chickens and turkeys chicken J. Nutr. 78(2): 155-161
MCP, DCP, HAP, Calcium sodium phosphate, β-TCP, 21, 22, 23, 24 7758-23-8
Wise DL, Trantolo DJ, Altobelli DE, Yaszemski MJ, Gresser JD and Schwartz
Encyclopaedic handbook of biomaterials and bioengineering. Part B: Applications. Vol 1
Dicalcium phosphate, tricalcium phosphate, monocalcium phosphate 21, 22, 24 7558-23-8 Cameron FK and Siedell A 1910 The action of water upon the phosphates of calcium. N/A J Am Chem Soc 26: 1454-1463
Moncalcium phosphate hydrate, dibasic calcium phosphate, basic tricalcium phosphate 21, 22, 24 7758-23-8 Carstensen JT 1988
Handling of non-sink conditions: In vitro dissolution rates of some common pharmaceutical calcium salts N/A
Drug development and industrial pharmacy, 14(4): 1971-1989
monocalcium phosphate, dicalcium phosphate, tricalcium phosphate, 21, 22, 24 7758-23-8 Frossard E, Tekely P and Grimal JY 1994
Characterisation of phosphate species in urban sewage sludges by high-resolution solid-state 31P NMR. sewage sludge European Journal of Soil Science. 45: 403-408
monocalcium phosphate, dicalcium phosphate, tricalcium phosphate/hydroxyapatite, octocalcium phosphate 21, 22, 24, n/a 7758-23-8 Lehr J.R. And Brown W.E. 1958
calcium phosphate fertilizers: II a petrographic study of their alteration in soils soil soil sci soc amer proc 22: 29-32
monocalcium phosphate, dicalcium phosphate, tricalcium phosphate/hydroxyapatite, octocalcium phosphate 21, 22, 24, n/a 7758-23-8 Terman G.L. Et al 1958
calcium phosphate fertilizers: I availability to plants and solubility in soils varying in pH ryegrass soil sci soc amer proc 22: 25-29
monocalcium phosphate, dicalcium phosphate, defluorinated phosphate 21, 22, n/a 7758-23-8 Sullivan TW and Douglas JH 1987
Bioavailability of bone precipitated dicalcium phosphate in turkey starter diets. turkey Poultry Sci(1): 182
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-44
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monocalcium phosphate, dicalcium phosphate, defluorinated phosphate, tricalcium phosphate 21, 22, n/a, 24 7758-23-8 Sullivan TW 1966
A triple response method fpr determining biological value of phosphorus sources with young turkeys turkey Poultry Science. 45:1236-1245
monocalcium phosphate, tricalcium phosphate 21, 24 7758-23-8 Ignatowicz S. 1980
effects of inorganic salts upon biology and development of acarid mites> IV. Effects of calcium phosphate surplus in food upon fecondity, life spam and development of copra mite Tyrophagus putrescentia acarid mites polish J entomo 50: 289-298
monocalcium phosphate, calcium pyrophosphate, monosodium phsohate, sodium acid pyrophosphate, calcium metaphosphate, sodium metaphosphate 21, 26, 2, 5, 7758-23-8 Peeler HT 1972
Biological avaiilability of nutrients in feeds: availability of major mineral ions. sheep J Anim Sci 1972. 35:695-712.
monocalcium phosphate, Magnesium phosphate
21, 29 7758-23-8 Greenwald I et al 1940The dissociation of Calcium and Magnesium Phosphates. N/A J Biol Chem, 135: 65-67
dicalcium phosphate, monosodium phosphate 22, 2 7757-93-9
R. A. ARGENZIO, J. E. LOWE, H. F. HINTZ, AND H. F. SCHRYVER 1974
Calcium and Phosphorus Homeostasis in Horses horse J Nutr. 104. 18-27
Calcium hydrogen orthophosphate, Calcium bis(dihydrogenorthophosphate), Ammonium dihydrogenorthophosphate
22, 21, 18 7757-93-9 Fernandes JIM et al 1999Relative bioavailability of phosphorus in feed and agricultural phosphates for poultry. poultry Poult. Sci. 78:1729-1736.
dicalcium phosphate dihydrate, dicalcium pyrophosphate 22, 26 7789-77-7 Buttner W. and Muhler J.C. 1958
The effect of feeding calcium phosphate salts with different solubilities on dental caries, the composition of the saliva and the femur of rats Rats J. D. Res. 37(5): 860-864
Calcium hydrogenorthophosphate, Dimagnesium phosphate
22, 29 7757-93-9 Webber MD 1970
Soluble complexes in the systems dicalcium phosphate dihydrate or dimagnesium phosphate trihydrate equilibrated with aqueous salt solutions N/A Can. J. Soil. Sci. 50:243-253
dicalcium phosphate and urea phosphate 22, 51 231-826-1
Hemingway RG, Parkins JJ and Ritchie NS 1972
Comparative effects of oral administration of urea and urea phosphate on the concentrations of ammonia and urea in the blood of sheep Sheep Br. Vet. J:. 128:
dicalcium phosphate dihydrate, octacalcium phosphate 22, n/a 7789-77-7 Moreno E.C. Et al 1960
stability of dicalcium phosphate dihydrate in aqueous solutions and solubility of octocalcium phosphate soils soil. Science soc. Proc: 99-102
beta-tricalcium phosphate, dicalcium phosphate 23, 22
7758-87-4, 7757-93-9 Nelson TS and Peeler HT 1961
The availability of phosphorus from single and combined phosphates to chicks chicken Poultry Sci 40:1321-1328
hydroxyapatite, beta-tricalcium phosphate 23, 24
7758-87-4, 12167-74-7 Ducheyne P, Radin S & King L 1993
The effects of calcium phosphate ceramic composition and structure on in vitro behaviour. I. Dissolution n/a Journal of Biomedical materials research. 27: 25-34
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-45
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
beta-tricalcium phosphate Tricalcium phosphate
23, 247758-87-4, 1306-06-
5Eisenberger S, Lehrman A and Turner WD 1938
The basic calcium phosphates and related systems. Some theoretical and practical aspects N/A Chem Rev. 26:257-96
hydroxyapatite, beta-tricalcium phosphate 23, 24
7758-87-4, 12167-74-7
Slosarczyk A, Paluszkiewicz C, Gawlicki M & Paszkiewicz Z 1977
The FITR Spectroscopy ans OXDR studies of calcium phosphate based materials produced from the powder precursors with different Ca/P ratios n/a Ceramics international. 23. 297-304
beta-tricalcium phosphate, deflurinated phosphate, dicalcium phosphate, monocalcium phosphate 23, n/a, 22, 21
7758-87-4, n/a, 7757-93-9, 7758-23-
8 Nelson TS and Walker AC 1964The biological evaluation of phosphorus compounds. A summary. chicken Poultry Sci 43:94-98
Tricalcium phosphate, Dicalcium phosphate, Monocalcium phosphate, Phosphoric acid
24, 22, 21, 48 12167-74-7 Cameron FK and Seidell A 1905 The Phosphates of Calcium I. N/A J AM Chem Soc 27(12): 1503-1512
tricalcium phosphate, monocalcium phosphate 24, 21 12167-74-4 Majumder S.K., Bano A. 1964
Toxicity of calcium phosphate to some pests of stored grain insects Nature 202: 1359-1360
tricalcium phosphate, monocalcium phosphate, dicalcium phosphate, monosodium phosphate, disodium phosphate, monopotassium phosphate, dipotassium phosphate, phosphoric acid
24, 21, 22, 2, 3, 12, 13, 48 12167-74-7
Satoh SH, Porn-Ngam N, Takeuchi T and Watanbe T 1993
Effect of Various Types of Phosphates on Zinc Availability to Rainbow Trout fish Nippon Suisan Gakkaishi. 59(8): 1395-1400
Hydroxyapatite, Tricalcium phosphate, Monocalcium phosphate monohydrate, Β-tricalcium phosphate, Dicalcium phosphate dihydrate, Vitreous calcium metaphosphate, Fluorapatite, Potassium calcium pyrophosphate
24, 21, 23, 22 12167-74-7 Huffman EO et al 1957Rates of Solution of Calcium Phosphate in Phosphoric Acid Solutions N/A Agricultural and Food Chemistry. 5(4): 266-275
TCP, DCP/DCPA and DCP dihydrate 24, 22 12167-74-4 Nancollas GH 1979Calcium phosphates – speciation, solubility and kinetic considerations. ACS Symposium 93: 475-497
hydroxyapatite, beta-tricalcium phosphate, 24, 23 1306-06-5
Raynaud S, Champion E, Bernache-Assolant and Laval JP 2001
Determination of calcium/phosphorus atomic ratio of calcium phosphate apatites using x-ray diffractometry N/A J. Am Ceram. Soc. 84(2): 359-366
hydroxyapatite, beta-tricalcium phosphate 24, 23 12167-74-4 Balmain N, Legros R and Bonel G 1982
X-ray Diffraction of calcined bone tissue: a reliable method for the determination of bone Ca/P molar. n/a Calcified Tissue International. 34:S93-S98
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-46
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
tricalcium phosphate, beta-tricalcium phosphate 24, 23 12167-74-4 Flatley TJ, Lynch KL and Benson M 1983
Tissue response to implants of calcium phosphate ceramic in the rabbit spine Rabbit Clinical orthop Rel Res. 179: 256-252
DICALCIUM PYROPHOSPHATE, SODIUM METAPHOSPHATE INSOLUBLE 26, 11 7790-76-3 Huffman E.O and Fleming J.D. 1960 rate and mechanism of its hydrolytic degradation . J. Phys. Chem. 64:240-244
dicalcium pyrophosphate, monocalcium phosphate, tetracalcium phopshate. 26, 21, 22, 7790-76-3
Chow L.C., Takagi S., Shern R.J., Chow T.H., Takagi K.K and Sieck B.A 1994
Effect on whole saliva of chewing gums containing calcium phosphates. human
Journal of dental research.73,26-32. http://jdr.sagepub.com/cgi/reprint/73/1/26.pdf
calcium pyrophosphate, ammonium pyrophosphate, calcium ammonium pyrophosphate 26, n/a, n/a 7790-76-3 Hossner L.R. And Melton J.R. 1970
Polyphosphate Hydrolysis of Ammonium, calcium and calcium ammonium pyrophosphates in selected Texas soils soil soil sci soc amer proc 34: 802-805
iron phosphate, aluminium phosphate, tricalcium phosphate, 27, 40, 24 10045-86-0 Cameron FK and Hurst LA 1904
The action of water and saline solutions upon certain slightly soluble phosphates. N/A
The Journal of The American Chemical Society. 26(8): 885- 913.
Dimagnesium phosphate, Ferric phosphate
29, 27 7757-86-0 Cameron FK and Bell JM 1907 The Phosphates of Magnesium and Iron N/A J Phys Chem 11(5): 363-368
MgHPO4.3H2O (newberite)Mg3(NH4)2(HPO4)4.8H2OMg3(NH4)2(HPO4)2.4H2O –A (Schertelite)Mg3(NH4)2(HPO4)2.4H2O –BMgNH4PO4.6H2O (struvite)
29, 30, 31, 60 7757-86-0 Frazier AW and Waerstad KJ 1992The phase system MgO-(NH4)2O-P2O5-H2O at 25°C. N/A Ind Eng Chem Res, 31: 2065-2068
disodium hydrogenorthophosphate, dipotassium hydrogenorthophosphate 3, 13
7558-79-4, 7758-11-4 Ravich MI and Popova ZV 1942 ? N/A Izv Akad Nauk SSSR. ?:268-273
disodioum phosphate, monosodium phosphate 3, 2, 7558-79-4
Bernstein D.S, Newton R.
1966
The effect of oral sodium phosphate on the formation of renal calculi and on idiopathic hypercalcuria. The Lancet. Nov. 19:1105-1107
disodium phosphate, calcium phosphate monobasic, calcium phosphate dibasic 3, 21, 22 7558-79-4 McClure F.J and Muller A. 1959
Further observations on the cariostatic effects of phosphates Rats J. D. Res. 38(4): 776-781
Na2HPO4, calcium phosphate monobasic, calcium phosphate dibasic 3, 21, 22 7558-79-4 McClure F.J. 1960
the cariostatic effect in white rats of phosphorus and calcium supplements added to the flour of bread formulas and to bread diets Rats J. Nutrition 72: 131-136
sodium phosphate (Na2HPO4), trisodium phosphate, sodium acid pyrophosphate, trisodium trimetaphosphate (3-hydrate), sodium metaphosphate, sodium hexametaphosphate, monopotassium phosphate, potassium pyrophosphate, potassium polyphosphate (add. Non-ip substances)
3, 4, 5, 8, 9, 10, 12, 15, 17 7558-79-4 Shibata H 1981
Antibacterial action against streptococuss mutans and inhibitory effect on the experimental Hamster caries of condense phosphates bacteria Fukuoka Igaku Zasshi 6:379-391
disodium phosphate dodecahydrate, phosphoric acid, 3, 48 7558-79-4 Nofre C., Dufour H. and Cier A. 1963 compared toxicity of 32 mineral anions in the mice mice
comptes rendus des sceances de l'academie des sciences 257: 791-794
disodium phosphate, sodium acid pyrophosphate, tetrasodium pyrophosphate, sodium metaphosphate, sodium tetrametaphosphate 3, 5, 7, 9, n/a 7558-79-4 Jen C.M.C, Shelef L.A. 1986
factors affecting sensitivity of Staphylococcus aureus 196E to polyphosphates bacteria applied and environmental microbiology: 842-846
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-47
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
disodium hydrogenphosphate, tetrasodiumpyrophosphate, monopotassium phosphate 3, 7, 12
7558-80-7, 7722-88-5, 7778-77-0 Menzel VH and Gabler C 1929
Uber verbindungen von alkaliphosphaten mit wasserstoffperoxyd N/A Z Anorg Chem. 177:187-198
disodium phosphate, tetrasodium pyrophosphate, trisodium trimetaphosphate, diammonium phosphate, calcium phosphate dibasic 3, 7, 8, 19, 22 7558-79-4 Van Reen R. and Ostrom C.A. 1962
Effects of dietary phosphate supplements on dental caries in the rat Rats J. D. Res 41: 875-882
disodium phosphate (DSP), tetrasodium polyphosphate, grahams salt, potassium dihydrogen orthophosphate, calcium phosphate monobasic, calcium phosphate tribasic, iron pyrophosphate
3, n/a, 9, 12, 21, 24, 28 7558-79-4 Wuembach et al 1966
Research into the toxicity and effects of polyphosphates on growth of cultures of amoeba, rotifers, tadpoles, and on the succession of organisms in cellulose decomposition
Amoeba and rotifer and Amphibian (Bufo bufo and Xenopus laevis)
institut fur Landwirtschaftliche Zoologie und bienenkunde, Report 33 pages
disodium phosphate, sodium acid pyrophosphate, sodium hexametaphosphate, phosphoric acid 3,5, 10, 48 7558-79-4 Konig K.G. Et al 1961
effects of some phosphates in a short-period rat caries experiment Rats Arch. Oral biol. 3: 258-270
trimagnesium phosphate, potassium tripolyphosphate 30, 16 7757-87-1 63rd JECFA 2004
Magnesium hydrogen phosphate prepared at the 26th JECFA (1982) published in 1982 and 1992. Revised at the 63rd JECFA (2004). n/a n/a
trimagnesium phosphate, trisodium phosphate 30, 4 7757-87-1 57th JECFA 2001 JEFCA N/A
Trimagnesium phosphate prepared at the 17th JECFA (1973) published in 1978 and 1992. Revised at the 57th JECFA (2001).
trisodium phosphate, monosodium phosphate 4, 2 7601-54-9
Bucher k., Bucher K.E., Walz D.1981
The topically irritant substance: Essentials-bio-test-predictions. Agents and actions, 11(5): 515-519
trisodium phosphate, monosodium phosphate 4, 2 7601-54-9
Simon I. 1939
Minimal Lethal Dose of some Sodium Salts Injected Intravenously. Boll Soc Ital Biol Sper, 14():136-137
trisodium phosphate, disodium phosphate 4, 3
7601-54-9, 7758-79-4
Abderhalden E.
1935
Handbuch der biologischen Arbeitsmethoden: Chemische und physikalische Untersuchungsmethoden der Pharmakologie und Toxikologie. ? 4: 1382 - 1383
trisodium phosphate, disodium hydrogenorthophosphate 4, 3
7601-54-9, 7758-79-4 Menzel 1937
Studien an alkaliphosphaten und arsenaten II): Tertiares natriumphosphat N/A Ztschr. Elektrochem. 43 (2): 104-
trisodium phosphate anhydrous, sodium acid pyrophosphate, tetrasodium pyrophosphate, tripotassium phosphate, monocalcium phosphate 4, 5, 7, 14, 21 7601-54-9 Weiner M. et al 1987
ABSTRACT: Dermal toxicity/ skin irritation studies on five inorganic phosphates Rabbits ?
trisodium phosphate anhydrous, sodium acid pyrophosphate, tetrasodium pyrophosphate, tripotassium phosphate, monocalcium phosphate 4, 5, 7, 14, 22 7601-54-9 Weiner M. et al 1986
ABSTRACT: Eye irritation studies on five inorganic phosphates Rabbits ?
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-48
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
trisodium phosphate, sodium acid pyrophosphate, trisodium trimetaphosphate, sodium hexametaphosphate 4, 5, 8, 10 7758-16-9 Behrens B. and Seelkopf K. 1933 Pharmacology of the meta phosphoric acids mice arch exp path pharmak 169():238
trisodium phosphate, tetrasodium pyrophosphate, sodium hexametaphosphates 4, 7 , 10 7758-16-9
Bell R.N.
1947
Estimation of triphosphoric and pyrophosphoric acids: In the presence of ortho- and metaphosphoric acids. n/a Anal. Chem. 19:97-100
trisodium phosphate, monosodium phosphate 4,2 Greenwald I 1915
Observations on the effect of intravenous injections of sodium phosphate rabbit, dog
Journal of Pharmacology and Experimental Therapy. 7: 57-61
trisodium phosphate, tetrasodium pyrophosphate, sodium metaphosphate insoluble, tetrapotassium pyrophosphate, sodium tripolyphosphate 4,7, 11, 15, 0 7601-54-9
Irani R.R. and Callis C.F.
1962Calcium and magnesium sequestration by sodium and potassium polyphosphates. n/a
Journal of the American Oil Chemists' Society. March: 156-159
Aluminium orthophosphate, hydroxyapatite 40, 24 7784-30-7
Hanawa T, Kaga M, Itoh Y, Echizenya T, Oguchi H and Ota M 1992
Cytotoxicities of oxides, phosphates and sulphides of metals. N/A Biomaterials. 13(1): 20 – 24
aluminium phosphate, iron phosphate 40, 27 7784-30-7 Marks J et al 1956A study of dust toxicity using a quantitative tissue culture technique. N/A British Journal of Industrial Medicine. 13: 187-191
aluminium phosphate, magnesium hydrogen phosphate 40, 29 7784-30-7 Boudraa M’hamed et al 1991
Etudes physico-chemiques de AlPO4, de MgHPO4.3H2O et leurs melanges. N/A
Acta Poloniae Pharmaceutica- Drug Research. 48(3-4): 63-68
Aluminium orthophosphate dihydrate, hydroxyapatite, dicalcium phosphate dihydrate, Iron orthophosphate dihydrate
40. 24, 22, 27 7784-30-7 Lindsay WL and Moreno EC 1960 Phosphate phase equilibria in soils N/A Soil sci soc Am J. 24(3):177- 182
sodium potassium polyphosphate, trisodium trimetaphosphate 46, 8 24315-83-1 Thilo E. and Wieker W. 1959
the hydrolyse of condensated phosphates in aqueous solution water Naturwissen, 46:367-373
sodioum monoflurophosphate 47 10163-15-2 Ripa LW & Leske GS 1985Clinical Trial of a Combined MFP-NaF Dentifrice Formulated at Different Concentrations Human NTIS
disodium fluorophosphate, monoammonium phosphate, monosodium phosphate 47, 18, 2 10163-15-2
Fisher AA
1986Contact Dermatitis From Foods and Food Additives. 582-594 and 851,855 and 904
Contact Dermatitis Third edition Lea & Febiger Philadelphia 1986
Phosphoric acid, Graham’s salt48, 11 7664-36-2 Eberly NE et al 1920
The system zinc oxide, phosphorous pentoxide and water at 25° and 37° N/A J Am Chem Soc, 42(7): 1433-1439
Phosphoric acid, Potassium dihydrogenorthophosphate, Tripotassium orthophosphate, Ammonium dihydrogenorthophosphate, Diammonium hydrogenorthophosphate, Triammonium phosphate 48, 12, 14, 18,
19 7664-38-2 Parker EG 1914The ternary systems, Potassium – Phosphoric acid – Water and Ammonia – Phosphoric acid – Water N/A J Phys Chem, 18: 653-661
phosphoric acid, monoammonium phosphate 48, 18 7664-38-2 Kubasova L V 1971 Polyphosphoric acids and their ammonium salts. Russian Chemical Reviews, 40 (1) 1 - 12.
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-49
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
phosphoric acid, diammonium phosphate, sodium acid pyrophosphate, sodium tripolyphosphate 48, 19, 5, 0 7664-38-2 Lohry R 2001
Ortho Vs. Poly. Author takes a look at the history and behaviour of ortho and polyphosphates. Fluid Journal N/A Fluid Journal
phosphoric acid, monocalcium phosphate, sodium hexametaphosphate 48, 21, 10 7664-38-2 Grant W M, . 1974 Toxicology of the Eye (Handbook) rabbit
Toxicology of the eye, Second Edition. Charles C Thomas USA
Phosphoric acid, iron phosphate 48, 27 7664-36-2 Carter SR and Hartshorne NH 1926
The system ferrous oxide-phosphoric acid-water and some of its oxidation products N/A ?
phosphoric acid, trisodium orthophosphate 48, 4 7664-38-2 Young JR et al 1988 classification without testing N/A Toxic in vitro, vol 2, no 1, pp 19-26, 1988
orthophosphoric acid, pyrophosphoric acid 48, 50 7664-38-2
Beranger-Yvon. A., Champighy M.L., Guyon D. 1958
Measure of photosynthesis and of growth, Chlorella alga (8 days culture)
algae (chlorella pyrenoidosa) revue de cytologie et de biologie vegetale (19): 433-452
Sodium pyrophosphate 5 (OR 7) 7758-16-9
Bloch-Frankenthal L.
1954The role of magnesium in the hydrolysis of sodium pyrophosphate by inorganic pyrophosphatase. rat (blood) Biochem J. 57,1: 97-92
sodium pyrophosphate 5 (OR 7) 7758-16-9 Natarajan A.T. And Ahnsrom G. 1968cytogenetic effects of inorganic pyrophosphate and 5-fluoro deoxyuridine plant (vicia faba) Hereditas 59 (2-3): 229
Sodium pyrophosphate 5 (OR 7) 7758-16-9 Salzer 1894 ? N/A Arch Pharm 232: 365-375
sodium acid pyrophosphate / sodium pyrophosphate 5 / 7, 7758-16-9 Daugherty F.M. 1951
Effect of some chemicals used in oil well drilling on marine animals
diverse marine invertebrates sewage ind. Wastes 23: 1282-1287
Sodium pyrophosphate (SAPP or TSPP) 5 or 7 7758-16-9 Bayer KJ 1869 1) Chemische Notizen N/A J Prakt Chem, 106: 501
Sodium pyrophosphate 5, 7758-16-9 Dowden B 1961
Cumulative toxicities of some inorganic salts to daphnia magna as determined by median tolerance limits Daphnia Proc La Acad Sci, 23: 77-85
sodium acid pyrophosphate, sodium tripolyphosphate 5, 0 7758-16-9
Molins RA, Kraft AA, Olson DG, Walker HW & Hotchkiss DK 1986
Inhibition of Clostridium sporogenes PA 3679 and Natural Bacterial Flora of Cooked Vacuum-Packaged Bratwurst by Sodium Acid Pyrophosphate and Sodium Tripolyphosphate With or Without Added Sodium Nitrite
bacteria Journal of Food Science. 51(3): 726-731
sodium acid pyrophosphate, potassium dihydrogenphosphate, tetrapotassium pyrophosphate, monocalcium phosphate, calcium dihydrogen pyrophosphate, calcium pyrophosphate
5, 12, 15, 21, 25, 26
7758-16-9, 7778-77-0, 7320-34-5, 7758-23-8, 14866-19-4,
7790-76-3 Morin C 1961
No 264. Etude des polyphosphates de sodium, potassium et calcium. II. Etude des polyphosphates de sodium N/A Bull. Soc. Chim. France: 1719-1740
sodium acid phosphate, monosodium phosphate 5, 2 7758-16-9 Boyd, E.M., Seymour K.G.W. 1946
untoward and toxic reaction of a range of different products rats Experimental Medecine and Surgery (4):223-227
sodium acid pyrophosphate, monosodium pyrophosphate 5, 2 7758-16-9
Dowden B F and Bennett H J.
1965 Toxicity of selected chemicals to certain animalsinvertebrates (various dependent on substance) j wpcf.37.1308-1316
sodium biphosphate and sodium phosphate mixture 5, 2 (?) 7758-16-9 Greenfield I 1941
The effect of the intravenous administration of phosphate solutions in normal rabbits rabbits J. Lab. Clin. Med. 7:68-70
sodium acid pyrophosphate, disodium phosphate 5, 3 7758-16-9
Sutton C.D. and Larsen S.
1964 Pyrophosphate as a source of phosphorus for plants. n/a Soil Sci. 97(): 196-201
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-50
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium acid pyrophosphate, trisodium phosphate, sodium tripolyphosphate 5, 4, 0 7758-16-9
Firstenberg-Eden R et al
1981Inhibition of Moraxella-Acinetobacter Cells by Sodium Phosphates and Sodium Chloride. Journal of Food Science 46: 579-582
sodium acid pyrophosphate, pyrophosphoric acid 5, 49 7758-16-9 Nociti F.H. Et al 2002 cementum: a phosphate-sensitive tissue rats (mutant) J. D. Res. 81(12): 817-821
sodium pyrophosphate, pyrophosphoric acid 5, 50 7758-16-9 McGilvery J.D. And Crowther J.P. 1954
the hydrolysis of the condensed phosphates. II a) the role of the hydrogen ion in the hydrolysis of sodium pyrophosphate. II b) the dissociation constants of pyrophosphoric acid soil canadian J chem. 32: 174-185
disodium dihydrogenpyrophosphate, trisodium hydrogen diphosphate 5, 6 7758-16-9
Marcy JA, Kraft AA, Hotchkiss DK, Molins RA, Olson DG, Walker HW and White PJ 1988
Effect of Acid and Neutral Pyrophosphates on the Natural Bacterial Flora of a Cooked Meat System
bacteria JOURNAL OF FOOD SCIENCE. 53(1): 28- 30
Potassium polyphosphate (Kurrol salt) mixture 2/3 tetrasodium pyrophosphate (TSPP) 1/3 disodium pyrophosphate (SAPP) 5, 7 7758-16-9
Van Esch GJ, Vink HH, Wit SJ, Van Genderen H 1957 the physiological effect of phosphates Mouse Arzneimittel-forsch 7():172-175
disodium dihydrogenpyrophosphate, tetrasodium pyrophosphate 5, 7 7758-16-9
Marcy JA, Kraft AA, Hotchkiss DK, Molins RA, Olson DG, Walker HW and White PJ 1988
Effect of Acid and Alkaline Pyrophosphate Blends on the Natural Flora of a Cooked Meat System
bacteria JOURNAL OF FOOD SCIENCE. 53(1): 25-27
sodium acid pyrophosphate, tetrasodium pyrophosphate 5, 7 7758-16-9
Boettge K., Jaeger K.H. and Mittenzwei H.
1957Das Adenylsäuresystem: neure ergebnisse und probleme. Arzneimittel-Forschung. Drug Research. 7:24-59
sodium pyrophosphate, sodium metaphosphate, sodium hexametaphosphate 5, 9, 10 7758-16-9 Omoto M. et al 1986
ABSTRACT: Effects of condensed phosphates as a food additive on the liver, Kidneys, muscles, and bones of the mouse mice toxicology lett suppl 31: P1-54
sodium acid pyrophosphate, sodium tripolyphosphate, sodium hexametaphosphate, sodium polyphosphate, calcium polyphosphate. 5, 9, 10, 7758-16-9
Seward RA, Lin CF & Melanchoris N 1986
heat sensitisation of Salmonella by polyphosphate bacteria Journal of food science. 51(2): 471-473
sodium pyrophosphate, sodium metaphosphate, sodium hexametaphosphate, tetrapotassium pyrophosphate, potassium metaphosphate, dicalcium phosphate
5, 9, 10, 15, 17, 22 7758-16-9 Fujita H. and Sasaki M. 1990
Mutagenicity test of food additives with salmonella typhimurium TA97 and TA102 bacteria ann. Rep. Tokyo Metr. Res. Lab. P.H. 41: 315-322
sodium acid pyrophosphate, tetrasodium pyrophosphate, sodium tripolyphosphate 5,7,0 7758-16-9
Lee RM, Bartami PA, Olson DG & Wiliams FD 1994
Bactericidal and Bacteriolytic Effects of Selected Food-Grade Phosphates, Using Staphylococcus aureus as a Model System Bacteria
Journal of Food Protection, Vol. 57, No. 4, Pages 276·283
Various 50, 48, 8, 11, 17,
22, 21 Various Farr TD 1950
Phosphorous Properties of the Element and Some of Its Compounds. By the Staff of the Division of Chemical Engineering. N/A
Tennessee Valley Authority Chemical Engineering Report No. 8
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-51
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Various
50, 49, 48, 47, 11, 10, 9
(all ortho-,pyro-, tri- phosphates,
0, 5, 7, 8, 10, 11, 47, 48, 49, 50) Various Audrieth 1950 TEXTBOOK n/a Inorganic syntheses Volume III: 85-117
polyphosphoric acid, magnesium hydrogenorthophosphate, sodium metaphosphate 51, 29, 9 8017-16-1 Ohta. M 1961
The effects of polyphosphoric acid and inorganic salts upon the respiration of Ehrlich Ascites Tumor Cells tumor cells Nihon Univ J. Med. 3: 365-385
sodium pyrophosphate 7 (or 5) Sabbatani L 1904 Funzione Biologica del Calcio ?Memorie della Reale Academia delle scienze di Torina 54(2a):459-529
various: sodium pyrophosphate 7 (or 5) Starkenstein E 1914
Uber die pharmakologische wirkung kalziumfallender sauren und der magnesium salze rabbit
Archiv fur experimentelle Pathologie und Pharmakologie ixxvii: 45-82
Sodium pyrophosphates 7 or 5 7722-88-5 ? 1928 The chemical news –Sodium pyrophosphates N/A
sodium pyrophosphate, Sodium tripolyphosphate 7(or 5), 0
7722-88-5, 7758-29-4
Watanabe M, Matsuura M and Yamada T 1981
The mechanism of hydrolysis of polyphosphates. V.the effect of cations on the hydrolysis of pyro- and triphosphates N/A Bulletin of the Chemical Society of Japan. 53(3): 738-741
sodium pyrophosphate, STPP ,sodium hexametaphosphate 7(or 5), 0, 10 7722-88-5 Watzel VDR 1942
Uber die hydrolysegeschwindigkeit von pyrophosphate, tripolyphosphat und hexametaphosphat. N/A Die Chemie. 55(47/48): 351-366
Sodium pyrophosphateSodium triphosphateSodium tetraphosphate 7, 0, 7722-88-5 Quimby OT 1954
Soluble crystalline polyphosphates – their purification, analysis and properties. N/A The Journal of Physical Chemistry, 58(8): 603-618
sodium pyrophosphate, sodium tripolyphosphate, sodium hexamaetaphosphate 7, 0, 10 7722-88-5 Zessin KG and Shelef LA 1988
Sensitivity of Pseudomonas strains to polyphosphates in media system
microorganisms; pseudomonas Journal of Food Science. 53(2):669-670
tetrasodium pyrophosphate, sodium tripolyphosphate, sodium polyphosphate 7, 0, 9 7722-88-5
Fingerhut M et al
1965Zur Frage Der Resorption von polyphosphaten (On the question of absorption of polyphosphates) rat
tetrasodium pyrophosphate, disodium phosphate 7, 2 7722-88-5
D. Jolley, W. Maher & P. Cullen
1998
Rapid Method for Separating and Quantifying Orthophosphate and Polyphosphates:Application to Sewage Samples. n/a Water Research Vol. 32, No. 3, pp.711-716
tetrasodium pyrophosphate, disodium phosphate, sodium tripolyphosphate 7, 2, 0 7722-88-5
Heitkemper DT, Kaine LA, Jackson DS and Wolnik KA,
?Determination of tripolyphosphate and related hydrolysis products in processed shrimp, n/a US FDA. pp 92-100.
tetrasodium pyrophosphate, disodium orthophosphate, calcium sodium phosphate, 7, 3 7722-88-5 Gardner J and Symes W 1911
The physiological action of some camphene phosphonates of sodium rat Biochemical Journal. 5: 390
tetrasodium pyrophosphate, trisodium phosphate 7, 4 7722-88-5 Smith R.S. Et al 1956 effects of synthetic detergents on water coagulation water j am wat wks ass 48: 55-69
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-52
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
tetrasodium pyrophosphate, trisodium phosphate, disodium phosphate, monosodium phosphate 7, 4, 3, 2 7722-88-5
Friedrich Kiermeier & Klement Möhler
1957
Zusammenfassende Übersichtsberichtsberichte: Zure Verwendung der Polyphosphate bei Lebensmitteln. Z. Lebensmittel-Unters. U. -Forsch., Rand 106 ? ?
tetrasodium pyrophosphate, sodium acid pyrophosphate 7, 5 7722-88-5
41st JECFA
1993
Tetrasodium pyrophosphate prepared at the 41st JECFA publisehd in 1993, superceding specifications prepared at the 37th JECFA, publisehd in 1992. Revised at the 55th JECFA (2000). n/a JEFCA
tetrasodium pyrophosphate, sodium polyphosphate 7, 9 7722-88-5
Lebron CI, Molins RA, Walker HW, Kraft AA, Stahr HM 1989
Inhibi'tion of Growth and Aflatoxin Production of Aspergilli in Medium Containing Phosphates yeat Journal of Food Protection, Vol. 52(1): 4-6
Tetrasodium pyrophosphate, sodium acid pyrophosphate, trisodium pyrophosphate, dicalcium pyrophosphate 7,5,6,26
7722-88-5, 7758-16-9, 14691-80-6,
7790-76-3 Corbridge DEC 1957Crystallographic data on some hypophosphates and pyrophosphates N/A Acta Cryst. 10: 85
sodium trimetaphosphate, sodium tetrametaphosphate, sodium tripolyphosphate 8, 0
7785-84-4, 7758-29-4 Watanable M, Sato S and Saito H 1975
The mechanism of the hydrolysis of condensed phosphates. III. The mechanism of the hydrolysis of trimeta- and tetrametaphosphates N/A
Bulletin of the Chemical Society of Japan 48(12): 3593-3597
sodium trimetaphosphate, sodium hexametaphosphate 8, 10 7785-84-4
Mitchell L C
1958
A paper chromatogragphic study of the effect of synthetic digestive fluids on the sodium salts of Tri-, Tetra-, and Hexametaphosphoric acids. n/a? Journal of the A. O. A. C, 41, 185-188.
sodium trimetaphosphate, sodium hexametaphosphate 8, 10 7785-84-4
Lanigan
2001
Final report on the safety assessment of sodium metaphosphate, sodium trimetaphosphate and sodium hexametaphosphate. International Journal of Toxicology.
trisodium trimetaphosphate, monocalcium phosphate 8, 21 7785-84-4 Koulourides T. 1974
ABSTRACT: Effect of CaHPO4 and TMP on carcigonicity in Human bovine enamel J. D. Res. 53: 606
sodium trimetaphosphate, tetrasodium pyrophosphate, disodium phosphate, sodium tripolyphosphate 8, 7, 3, 0 7785-84-4
Dionex.
2002
Determination of polyphosphates using ion chromatography with suppressed conductivity detection. n/a Dionex analysis condensed phosphates 2002.pdf
sodium trimetaphosphate8,
[35] 7785-84-4 Henry C. and Navia J. 1969
sodium trimetaphosphate influence on the early development of rat caries and concurrent microbial changes Rats Caries Res. 3: 326-338
sodium polyphosphate, sodium tripolyphosphate, tetrasodium pyrophosphate 9, 0, 7
68915-31-1, 7758-29-4, 7722-88-5 Matsuura N, Lin T and Kobayashi Y 1970
Ion-exchange chromatographic analysis on the chain length of polyphosphate products N/A Bulletin of the Chemical Society of Japan. 43: 2850-2858
sodium metaphosphate, sodium hexametaphosphate, potassium metaphosphate, calcium phosphate dibasic 9, 10, 17, 22 68915-31-1 McClure F.J. 1963
Further studies on the cariostatic effect of organic and inorganic phosphates Rats J. D. Res. 42(2): 693-699
sodium hexametaphosphate, potassium metaphosphate 9, 17 68915-31-1 Lang K. et al 1955 the metabolism of polyphosphates rats Biochemische Zeit. 327: 118-125
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-53
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium metaphosphate, dicalcium phosphate 9, 22 10124-56-8 Lock S.O. Et al 1987
extracellular release of enzymes from macrophages in vitro for measuring cellular interaction with particulate and non-particulate materials mammalian cells Toxic. In vitro 1(2): 77-83
sodium metaphosphate, sodium trimetaphosphate 9, 8 10124-56-8 Wang T and Li SFY 1998
Separation of synthetic inorganic polymers of condensed phosphates by capillary gel electrophoresis with indirect photometric detection. n/a Journal of Chromatography A, 802:159-165
Fluorine from rock phosphate N/A N/A Zumpt I 1975 Chronic flouride poisoning in sheep Sheep J S Afr Vet Ass, 46: 161-163
Various N/A N/A Molins RA Phosphates in Food (handbook) Various N/A
phosphorus N/A N/A
Integrated risk information system. ReferenceDoseForChronicOralExposure Http://www.epa.gov/iris/subst/0697.htm
Sodium potassium phosphate N/A N/A Nanmann E 1933Uber die Beeinflussung von Daphnia magna durch einige Salze und Salzmischungen Daphnia
Kungl Fysiografiska Sallskapets I Lung Forhandlingar Bd 4, Nr 2
Iron (III) pentandenionateIron (III) diazaalkanolate N/A N/A Bullock JI et al 1992
Contact uptake of metal compounds and their molluscicidal effects on the slug, Deroceras reticulatum (Muller) (Pulmonata: Limacidae) Slug Crop protection, 11: 329-334
Fire Retardants and Firefighting Foams N/A N/A Adams R and Simmons D 1999Ecological effects of fire fighting foams and retardants. N/A
Conference Proceedings, Australian Bushfire Conference, Albury July 1999
Calcium metaphosphate CMP N/A 77489-25-9 Allmaras R.R. 1965 Hydrolysis of condensed phosphates in soils soil soil science soc proceedings 487-488
No IP substances studied N/A N/A Anderson BG 1944
the toxicity thresholds of various substances found in industrial wastes as determined by the use of daphnia magna daphnia magna. Sew Works J. 16(6):1156-1165
No IP substances investigated N/A N/AArlauskas A, Baker RSU, Bonin AM, Tandon RK, Crisp PT and Ellis J 1985 Mutagenicity of metal ions in bacteria Environmental Research. 36: 379-388
ultraphosphates N/A N/A Averbuch-Pouchot and Durif A 1992 Crystal Chemistry of Ultraphosphates n/a Zeeitschrift fur Kristallographic 201: 69-92
Ammonium magnesium phosphate along with a number of other phosphates N/A N/A Bassett H and Bedwell WL 1933
Studies of Phosphates. Part II. Orthophosphates of the type M3(PO4)2,XH2O. 871-882Part IV. Pyrophosphates of some bivalent metals and their double salts, and solid solutions with sodium pyrophosphates.
Bassett & Bedwell Studies of Phosphates I - IV 1412-1429 and 871-882
No IP substances evaluated N/A N/A Bautista EM and Alexander M 1972Reduction of inorganic compounds by soil microorganisms. microorganisms Soil Sci Soc Am J. 36(6)
Sodium and potassium polyphosphate N/A N/A Bennet et al 1957Hydrolytic degradation of polyphosphates in liquid detergent formulations N/A Soap and Chem Spec 33: 44-47
No IP substances investigated N/A N/ABiesinger KE, Lemke AE, Smith WE and Tyo RM 1976
Comparative toxicity of polyelectrolytes to selected aquatic animals. fish J Water Pollut Control Fed. 48(1):183-187
Calcium metaphosphate CMP N/A N/A Bird HR, Caskey CD 1943Amorphous calcium metaphosphate as a phosphorous supplement for chicks white leghorn chickens Poultry Sci. 22:333-334
Unknown N/A N/A Blahm TH 1979Toxicity of chemical fire retardants to juvenile coho salmon and rainbow trout Fish
Diss Abstr Int B Sci Eng - phD thesis Univ Idaho, ID 40, 39(9): 4115
Phos-Chek XA, Fire-Trol 931 N/A N/A Blahm TH and Snyder GR 1973Effect of Chemical Fire Retardants on the Survival of Juvenile Salmonids. N/A
National Marine Fisheries Service Environmental Facility Prescott, Oregon.
Unknown N/A N/A Boyer J 1980
Toxicite apparentte de certain engrais phosphates et intoxication manganique induite. Journee Georges Aubert. ? ?
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-54
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Fire-Trol GTS-R, Fire-Trol LCG-R, Phos-Chek WD-881 and Ansul Silv-Ex and Phos-Check D75-R N/A N/A Buhl KJ and Hamilton SJ 1998
Acute Toxicity of Fire-Retardant and Foam-Suppressant Chemicals to Early Life Stages of Chinook Salmon (Oncorhynchus tshawytscha) Fish Environmental Toxicology and Chemistry, 17(8): 1589-1599
Fire-Trol LCA-F, Fire-Trol LCM-R and Phos-Chek 259F, FireFoam 103B, FireFoam 104, Fire Quench, ForExpan S, Pyrocap B-136 and other chemicals. N/A N/A Buhl KJ and Hamilton SJ 2000
Acute Toxicity of Fire-Control Chemicals, Nitrogenous Chemicals and Surfactants to Rainbow Trout. Fish
Transactions of the American Fisheries society. 129: 408-418
Phos-Chek G75-F and Silv-Ex N/A N/ABuscemi DM, Hoffman DJ, Vyas NB, Spann JW and Kuenzel WJ 2007
Effects of Phos-Chek G75-F and Silv-Ex on red-winged blackbird (Agelaius phoeniceus) embryos. Birds Environmental Pollution, 148: 312-315
Phos-Chek G75-F and Silv-Ex N/A N/ABuscemi DM, Hoffman DJ, Vyas NB, Spann JW and Kuenzel WJ 2002
Effects of Phos-Chek G75-F and Silv-Ex on Developing Northern Bobwhite Quail (Colinus virginianus) Birds Erch Eviron Contam Toxicol 43: 330-337
No phosphates N/A N/A Cameron FK and Brown BE 1905The solubility of calcium sulphate in solutions of other salts N/A J Phys Chem 9(3): 210-215
superphosphate N/A N/A Chaurasia LC anf Rahtor JS 1980Mitotic effects of superphosphate on somatic cells of Allium sativum plants Sci Cult, 46: 150-152
Single super phosphate N/A N/A Chaurasia OP and Sinha Sp 1986Cytogenic effects of single super phosphate on onion root tip cells. plants Perspectives in cytology and genetics, 5: 349-352
Single Super Phosphate N/A N/A Chaurasia OP and Sinha SP 1988Induction of Mitotic-Chromosome Anomalies in Mice by Single Super Phosphate Mice Cytologia, 53: 485-489
Phosphorous N/A N/A Corbridge DEC 1974 The Structural Chemistry of Phosphorus. N/AAmerican Elsevier Publishing Company, Inc. ISBN: 0-444-41073-2
SUPERPHOSPHATE N/A N/A East NE 1993Accidental superphosphate fertiliser poisoning in pregnant ewes. sheep JAVMA. 203(8): 1176-1177
Unspecified N/A N/A Elmstahl S et al 1998Increased Incidence of Fractures in Middle-aged and Elderly Men with low intakes of phosphorus and zinc human Osteoporos Int 8:333-340
Phosphorous N/A N/A Emsley J and Hall D 1976
The Chemistry of Phosphorus. Environmental, organic, inorganic, biochemical and spectroscopic aspects. N/A John Wiley and Sons. ISBN: 0-470-23869-0
Phosphorous trichloride, phosphorous pentachloride, phosphorous oxychloride, phosphoryl chloride, phosphorous sesquisulfide N/A N/A EPA 1990
EPA Summary review of health effects associated with elemental and inroganic phosphorous compounds: Health issue assessment rabbits, fish EPA/600/8-89/072
sodium ammonium phosphate N/A 13011-54-6 Fazekas, IG 1954Enlargement of parathyroid glands by simple acidic compounds rabbits J. Anim. Sci. 80:1690-1695
No IP substances investigated N/A N/A Freeman L and Fowler I 1953Toxicity of combinations of certain inorganic compounds to Daphnia magna stratus. Daphnia Sewage and Industrial wastes. 25(10): 1191-1195
Fire-Trol GTS-R, Fire-Trol LCG-R, Phos-ChekD75-F, Phos-Chek WD-881 and Silv-Ex. N/A N/A
Gaikowski MP, Hamilton Sj, Buhl KJ, McDonald SF and Summers CH 1996
Acute toxicty of Firefighting Chemical Formulations to Four Life Stages of Fathead Minnow. Fish Ecotoxicology and Environmental safety. 34: 252-263
Fire-Trol GTS-R, Fire-Trol LCG-R, Phos-ChekD75-F, Phos-Chek WD-881 and Silv-Ex. N/A N/A
Gaikowski MP, Hamilton Sj, Buhl KJ, McDonald SF and Summers CH 1996
Acute Toxicity of Three Fire-Retardant and Two Fire-Suppressant Foam Formulations to the Early Life Stages of Rainbow Trout (Oncorhynchus mykiss) Fish Environmental Toxicology and Chemistry, 15(8): 1365-1374
No IP substances investigated N/A N/A Gersich FR and Hopkins DL 1986Site-specific acute and chronic toxicity of ammonia to Daphnia magna straus Daphnia Environmental Toxicology and Chemistry, 5(5): 443-447
ammonium pyrophosphate ? (NH4)2 HP2O7 . H2O N/A N/A Gilliam J.W. And Sample E.C. 1968
Hydrolysis of pyrophosphates in soils: pH and biological effects soils soil science 106(5): 352-357
Iron compounds N/A N/AGold MD(Ed.) Hoppe JO, Marcelli GMA, Tainter ML 1955
Progress of Medical Science. Therapeutics: A review of the toxicity of iron compounds. various Am J Med Sci. 230(5): 558-571
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-55
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
No IP substances investigated N/A N/A Hsia MTS 1987
Use of scintillometric quantitation of unscheduled DNA synthesis in isolated rat hepatocytes for the screening of genotoxic agents. rat hepatocytes Cell biology and Toxicology. 3(2): 127-
cyclophosphates N/A N/A Kalliney SY 1972 Cyclophosphates n/a Topics in Phosphorous Chemistry, 7: 255-309
various N/A N/A Kanazawa T 1989 Inorganic phosphate materials N/A Materials science monographs. 52 (Book)
Unidentified inorganic phosphate N/A N/A Kanematsu N and Kada T 1978 Mutagenicity of metal compounds. microorganisms Unknown source. 215-216
no IP substances N/A N/A Kempf CA, Greenwood DA & Nelson VE 1937 Studies relating to the toxicity of fluorine compounds mice, rats, dogs J. Lab. Clin. Med. 22:1133-1137
Various N/A N/A Kent JA (Ed) 1992 N/A Riegel's handbook of industrial chemistry. 9th Ed
triammomium pyrophosphate monohydrate TPP N/A N/A Khasawneh F.E. Et al 1974
reactions of ammonium ortho- and polyphosphate fertilizer in soil: I Mobility of Phosphorus soils soil sci soc amer proc 38: 446-451
triammomium pyrophosphate monohydrate TPP N/A N/A Khasawneh F.E. Et al 1979
reactions of ammonium ortho- and polyphosphate fertilizer in soil: II Hydrolysis and reactions with soil soil soil sci soc amer proc 43: 52-58
Single Super Phosphate N/A N/A Konar SK and Sarkar SK 1982 Acute toxicity of agricultural fertilizers to fishes. Fish Geobios, 10: 6-9
Mg-substituted HAP N/A N/ALandi E, Logroscino G, Proietti L, Tampieri A, Sandri M and Sprio S 2008
Biomimetic Mg-substituted hydroxyapatite: from synthesis to in vivo behaviour. N/A J MaterSci: Mater Med. 19:239-247
Phos-Chek G75-F N/A N/A Larson Dl and Newton WE 1996
Effects of Fire Retardant Chemicals and Fire Suppressant Foam on North Dakota Prairie Vegetation. Plants
Proceedings of the North Dakotak Academy of Science, 50: 137-144
Fire-Trol GTS-R and Phos-Check D75-R N/A N/A Little EE and Calfee RD
Environmental Persistence and Toxicity of Fire-Retardant Chemicals, Fire-Trol GTS-R and Phos-Chek D75-R to Fathead Minnows Fish
UNKNOWN N/A N/A Locke A 1990Zooplankton Responses to Acidification: A Review of Laboratory Bioassays Zooplankton Water, Air and Soil Pollution, 60 :135-148
Chlorinated trisodium phosphate N/A N/A Loveday KS et al 1986
In vitro cytogenic testins using sister chromatid exchange and chromosome aberration endpoints in CHO cells.
Chinese hamster (CHO cells)?
Abstracts of the eighteenth annual meeting of the evironmental mutagen society.
Chlorinated trisodium phosphate N/A N/A Loveday KS et al 1987
In vitro cytogenic testins using sister chromatid exchange and chromosome aberration endpoints in CHO cells.
Chinese hamster (CHO cells)?
Abstracts of the eighteenth annual meeting of the evironmental mutagen society.
Chlorinated trisodium phosphate N/A N/A Loveday KS et al 1989
Chromosome Aberration and Sister Chromatid Exchange Tests in Chinese Hamster Ovary Cells In Vitro: II. Results With 20 Chemicals
Chinese hamster CHO cells Environmental and Molecular Mutagenesis, 13: 60-94
Not an IP paper N/A N/A Lowe J and Sullivan JB Jr 1992 Hazardous materials toxicology N/A Clinical principles of environmental health : 1053-62
Ammmonium flurophosphate N/A N/A MacPhee C and Ruelle R 1969Lethat effects of 1888 chemicals upon four species of fish from Western North America Fish Forest, wildlife and range experiment station. Bulletin No. 3
Inorganic phosphates not investigated N/A N/A Marzin DR and Phi HV 1985Study of the mutagenicity of metal derivatives with Salmonella typhimurium TA102. Bacteria Mutation Research. 155: 49-51
No IP substances investigated N/A N/A Mayes MA 1985Acute and chronic toxicity of ammonia to freshwater fish: a site specific study fish Environmental toxicology and chemistry, 5(5): 437-442
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-56
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Fire-Trol GTS-R, Fire-Trol LCG-R, Phos-ChekD75-F, Phos-Chek WD-881 and Silv-Ex. N/A N/A
McDonald SF, Hamilton SJ, Buhl KJ and Heisinger JF. 1996
Acute Toxicity of Fire Control chemicals to Daphnia magna (Straus) and Selenastrum capricornutum (Printz) Daphnia, algae Ecotoxicology and environmental safety, 33: 62-72
Fire-Trol GTS-R, Fire-Trol LCG-R, Phos-ChekD75-F, Phos-Chek WD-881 and Silv-Ex. N/A N/A
McDonald SF, Hamilton SJ, Buhl KJ and Heisinger JF. 1997
Acute Toxicty of Fire-Retardant and Foam-Suppressant Chemicals to Hyalella Azteca (Suassure) Amiphod Environmental Toxicology and Chemistry, 16(7): 1370-1376
UNKNOWN N/A N/A Menzel 1932 Sieg alkaliphosphates N/A Ztschr. Elektrochem. 58(5): 283-299
Polyphosphate and superphosphate (fertilisers) N/A N/A Miner G and Kamprath E 1971
Reactions and availability of banded polyphosphate in field studies N/A Soil sci Soc Am J. 35: 927-930
N/A N/A N/AMorris R, Taylor EW, Brown DJA and Brown JA 1987 Acid Toxicity and Aquatic Animals. Cambridge University Press. ISBN: 978-0-521-33435-8
Inorganic phosphates not investigated N/A N/A Nishimura M and Umeda M 1978Mutagenic effects of some metal compounds on cultured mammalian cells. Unknown source
Phos-Chek XA N/A N/A Norris LA et al 1978A Report of Research on the Behaviour and Impact of Chemical Fire Retardents in Forest Streams N/A N/A
Sodium ammonium phosphate N/A N/A Pagano DA and Zeiger E 1992Conditions for detecting the mutagenicity of divalent metals in Salomnella typhimurium. bacteria Environmental and Molecular mutagenesis. 19: 139-146
Inorganic phosphates not investigated N/A N/A Paton GR and Allison AC 1972Chromosome damage in human cell cultures induced my metal salts. Mutation research. 16(3): 332-336
N/A: sodium fluoride N/A N/A Pindborg J 1957The effect of 0.025 and 0.0125 dietary sodium fluoride on the rat kidney Rat Odont Rev. 8: 331-334
phosphate carriers N/A N/A Plate H and Mathews D 1984Relative safety of common fertilizer materials for planter application N/A
Abstr Pap Am Chem Soc 188th American Chemical Society Meeting Piladelphia Aug 26-31 1984
zinc phosphates' N/A N/A Salmon JE and Terrey H 1950
The systems zinc oxides - phosphoric oxide - water and manganous oxide-phosphoric oxide-water at temperatures between 25° and 100° n/a J Chem Soc. Unknown vol: 2913-2924
superphosphate N/A N/A Sarkar SK 1989Toxicity Evaluation of Superphosphate on Some Aquatic Invertebrates Exposed to Temperature.
zooplankton, worm, larvae and molluscs J Environ Biol, 11(2): 97-100
sodium hexametaphosphate : ESCOFOS (not applicable to SHMP - substance is a formulation) N/A N/A Saylor JF and Kamienski FX 1971
Initial submission: rabbit eye irritant classification study with sodium hexametaphosphate with cover letter dated 082892 Rat Stauffer Western RC NTIS OTS0545336 (T-1729)
sodium hexametaphosphate : ESCOFOS (not applicable to SHMP - substance is a formulation) N/A N/A Saylor JF and Kamienski FX 1971
Initial submission: rabbit eye irritant classification study with sodium hexametaphosphate with cover letter dated 082892 Rabbit Stauffer Western RC NTIS OTS0545336 (T-1729)
sodium hexametaphosphate : ESCOFOS (not applicable to SHMP - substance is a formulation) N/A N/A Saylor JF and Kamienski FX 1971
Initial submission: rabbit eye irritant classification study with sodium hexametaphosphate with cover letter dated 082892 Rabbit Stauffer Western RC NTIS OTS0545336 (T-1729)
No IP substances investigated N/A N/A Schardein JL 1993 Chemically induced birth defects. N/A 2nd edition. 842-869
Fire Retardants N/A N/A Seymour B, Collet NG 2009
Effects of Fire Retardant Application on Heathland Surface-Dwelling Ant Species (Order: Hymenoptera; Family Formicidae) in Victoria Australia Invertebrates Forest Ecology Management, 257: 1261-1270
No inorganic phosphates investigated. N/A N/A Shafer EW and Bowles WA 1985 Acute oral toxicity and repellency of 933 chemicals to House and Deer miceMiceArchives of Environmental Contamination and Toxicology. 14:111-129
unknown N/A N/AShpunt SY, Belopolskii AP & Shulgina MN 1951 unknown n/a Zh Prikl Chim. 24: 404-412
Aluminium N/A N/A Sjogren B and Elinder CG 1993 Aluminium N/A Nordic expert group. Arbete och Halse. 1:55-84
No IP substances reported N/A N/ASmith FA , Gardner DE, Leone NC and Hodge HC 1960
The effects of the absorption of fluoride. V. The chemical determination of flouride in human soft tissues following prolonged ingestion of fluoride at various levels Human AMA Arch. Indust. Health. 21: 330-332
N/A N/A N/A Spencer H 1975Effect of calcium and phosphorus on fluoride metabolism in man. human J. Nutr. 105(6): 733-740.
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-57
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Sodium glycerophosphate N/A N/A Spencer H 1978Effect of phosphorus on the absorption of calcium and on the Calcium balance in Man. human J. Nutr. 108:447-457
Phosphate berlinite (AIPO4) N/A N/A Stacy 1958Tissue changes in rats lungs caused by hydroxides, oxides and phosphates of aluminium and iron rat J Path Bact 77: 417-426
Phosphate ore N/A N/A Stayner LM et al 1985A retrospective cohort mortality study of a phosphate fertilizer production facility Human Arch Environ Health, 40: 133-138
Not applicable - review of assays to determine available phosphorous N/A N/A Sullivan TW and Douglas JH 1990
Phosphorious bioassays - Developments in five decades N/A
Presented at the Pitman-Moore Nutrition for the Nineties Conference, Bloomington, MN, September 17, 1990. 18-
DCP (not chemical – precipitated from bone) compared to commercially available forms. N/A N/A Sullivan TW et al 1994
Biological value of bone-precipitated dicalcium phosphate in turkey starter diets. turkey Poultry Science. 73: 122-128
Calcium aluminium phosphate N/A N/A Taylor AW and Gurney EL 1964The dissociation of calcium aluminium phosphate, CaAlH(PO4)2.6H20. N/A Soil Sci. Soc. Am J. 28:63-65
condensed phosphates N/A N/A Thilo E 1955Hydrolysis of condensed phosphates in aqueous solution water and soil Angewandte Chemie, 67:141-185
Radiolabelled phosphate N/A N/A Tomatis 1973 Transplacental Carcinogenesis N/A WHO
condensed phosphates N/A N/A Topley B 1949 Physical properties n/a Q Rev Chem Soc. 3:345-370
Serum phosphorous N/A N/A Tornblom N 1949On the functional relationship between the pituitary gland and the parathyroids Acta Endocrinol Suppl, 4: 1-76
Ferrous and Ferric ammonium sulphate N/A N/A Underwood EJ 1938A Comparison of Ferrous and Ferric Iron in the Nutrition of the Rat. Rat Journal of Nutrition, 16(3): 299-308
UNKNOWN N/A N/A Van Wazer JR 1954 ? N/A J Phys Chem. 58: 739
orthophosphate, pyro- and tripolyphosphate mixtures N/A N/A
Van Wazer JR, Griffith EJ and McCullough JF 1954
Analysis pH titration of soluble phosphates and their mixtures Anal. Chem. 26: 1755 – 1760
Octocalcium phosphate N/A N/A Verbeeck RMH and Devenyns JAH 1990The effect of the solution Ca / P ratio on the kinetics of dissolution of octocalcium phosphate. Journal of Crystal Growth. 102: 647-657
No IP substances investigated N/A N/A Vernot EH et al 1977
Acute toxicity and skin corrosion data for some organic and inorganic compounds and aqueous solutions. Rabbit, rat Toxicology and Applied Pharmacology. 42:417-423
sodium cyclo-triphosphate, sodium cyclo-trimetaphosphate n/a n/a Watanabe M 1982
The mechanism of the hydrolysis of polyphosphates. VI. The effect of cations on the hydrolysis of cyclo-tri- and cyclo-tetraphosphates N/A
Bulletin of the Chemical Society of Japan. 55(12): 3766-3769
calcium tetraphosphate N/A N/AWatanabe W, Suzumori H, Maeda M and YamadaT 1980
The synthesis and decomposition of calcium tetraphosphate N/A Bulletin of the Chemical Society of Japan. 35: 2663-2665
sodium and potassium phosphates N/A N/A Wendrow B & Kobe KA 1954The alkali orthophosphates. Phase equilibria in aqueous solution. n/a Chem Rev. 54: 891-924
UNKNOWN N/A N/A Wenger P 1911 Tables N/A Annuelles. 2: 411-413
Chemonics Fire Foam 103Monsanto Phos-Chek WD 861, 881Wormal SILV-EXAngus Forexpan3m FB 100
N/A N/A Wheeler IP 1989 Toxicological Review of Fire Fighting Foams. N/A
Prepared by Norecol Environmental Consultants Ltd on behalf of Manager, Fire Management Forest Protection Branch British Columbia.
ferric chloride N/A N/A Wien EM and Van Campen DR 1991
Ferric Iron Absorption in Rats: Relationship to Iron Status, Endogenous Sulfhydryl and Other Redox Components in the Intestinal Lumen Rat Journal of Nutrition 121(6): 825-831
chlorinated trisodium phosphate N/A N/A Zeiger E et al 1988Salmonella Mutagenicity tests: IV. Results from the testing of 300 Chemicals Salmonella
Environmental and Molecular Mutagenesis. 11 (suppl 12) 1-158
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-58
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
octacalcium phosphate N/A N/A Zhang J 1992Kinetics and mechanisms of octocalcium phosphate at 37°C. J. Phys. Chem. 96: 5478-5483
polyphosphate' n/a n/a Kornberg A 1995Inorganic polyphosphate: toward making a forgotten polymer unforgettable n/a J. Bacteriol. 1n(3):491-496.
various n/a n/a Deshpande SS 2002 Handbook of Food Toxicology various n/a
unknown n/a n/a Laflamme GH & Jowsey J 1972Bone and Soft Tissue Changes with Oral Phosphate Supplements dogs The Journal of Clinical Investigation. 51: 2834- 2840
phosphorus' n/a n/a
J. L. Montgomery, J. R. Blanton, Jr., R. L. Horst, M. L. Galyean, K. J. Morrow, Jr., D. B. Wester and M. F. Miller 2004
Effects of biological type of beef steers on vitamin D, calcium, and phosphorus status cows J Anim Sci 2004. 82:2043-2049.
various n/a n/a NRC 2005 NRC Mineral tolerance of animals various n.a
no IP substance tested n/a n/a Charles OW 1975The effect of calcium source and level on egg shell quality hens Poultry Science. 54: 1744
no IP substance tested n/a n/ajoyce Jr, Pierce KR, Romane WM and Baker JM 1971
clincial study of nutritional secondary hyperparathyroidism in horses. horse
Journal of the American vetinary medical association. 151(12): 2033-2043
various polyphosphates n/a n/a Maier, S. K. 1999
Die antimikrobielle Wirkung von Polyphosphaten. Ph.D. thesis. Technical University of Munieh. Freising, Germany. n/a TOC( SUPPL: *)
unknown n/a n/a Radkowski, М. and Kafel, S. 1985Effect of polyphosphates оп lactic acid bacteria of processing importance unknown Med Weter 400:328-329
inorganic phosphate' n/a n/a Strange, J. R. 1977
Effect of High Levels of Inorganlc Phosphate on Aquatic Organisms ln Phosphate-Rlch Environments unknown
Gov. Rep. Announce. Index (U.S) NTIS PB263290. 77(9):181
various n/a n/a Weinberg ED 1974Secondary Metabolism: Control by Temperature and inorganic phosphate n/a
Developments in Industrial Microbiology. Handbook. Chap 8
various n/a n/a Ellinger RH 1972 CRCF phosphates as food ingredients n/a Handbook
Sodium Ferric Pyrophosphate N/A N/A Brusick D 1975Mutagenic Evaluation of Compound FDA 73-82 010045871 Sodium Ferric Pyrophosphate Yeast and Bacteria NTIS
ferric sodium pyrophosphate N/A N/A Brusick D 1975Teratologic evaluation of FDA 73-82 ferric sodium pyrophosphate in mice and rats. mice and rats NTIS
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-59
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
concentrated super phosphate, diammonium phosphate n/a, 18 N/A Struwe FJ, Sullivan TW and Kuhl HJ 1976
Evaluation of phosphated egg shell and fertilizer phosphates in turkey starter diets1,2,3 turkey Poultry Sci. 55:1691-1699
Various Various Various Lide D R. 2009 CRC Handbook of chemistry and physics N/A CRC Handbook of chemistry and physics
various various various Gillis MB et al 1954Studies on the biological value of inorganic phosphates. N/A J. Nutr. 52:115-125.
polyphosphate' 'orthophosphate' Various Various Finnstein M and Hunter J 1967Hydrolysis of condensed phosphates during aerobic biological sewage treatment. microbes Water Research, Pergamon Press, 1: 247-254
pyrophosphate, tripolyphosphate various various Finstein MS and Hunter JV 1967Hydrolysis of condensed phosphates during aerobic biological sewage treatment. N/A Water Research, Pergamon Press, 1: 247-254
various various various Averbuch Pouchot MT and Durif A 1991 Crystal chemistry of oligophosphates N/A Annu. Rev. mater. Sci. 21:65-92
various various various Averbuch-Pouchot MT and Durif A 1996 Topics in Phosphate Chemistry N/A N/A
Various VARIOUS Various Budavari S et al 1996The Merck Index, An Encyclopaedia of Chemicals, Drugs and Biologicals Twelfth Edition Merck & Co., Inc. Whitehouse Station, NJ.
various various various Durif A 1995 Crystal Chemistry of Condensed Phosphates. N/A Plenum Press, New York.
various
Various various
Ebel JP
1958Action Physiologique et Toxicologique des Phosphates Condensés. Impremerie Nationale J.P.831041 : 57-97
various various various Gillis MB et al 1949The utilization by the Chick of phosphorus from different sources. chick J. Nutr. 35(2):195-207
Various various Various GRAS 1973GRAS (generally recognised as safe) food ingredients - Phosphates.
Franklin Institute Research Laboratories 806-C3378-01-7301.
Various Various n/a Lewis RJ Lewis – Sax Dangerous Properties Volume 18
various various various Madhavi DL, et al 1996Food Antioxidants. technological, toxicological and health perspectives N/A N/A
various various various Mellor JW 1912 Modern Inorganic Chemistry N/A N/A
various various various Motzok I, Arthur D and Branion HD 1956Utilization of phosphorus from various phosphate supplements in chicks chicken Poultry Sci. 35: 627-649
Various phosphates Various Various osterheld 1972 Nonenzymic hydrolysis at phosphate tetrahedra N/A
Various substances various various Siedell A 1940
Solubilities of Inorganic and Metal Organic Compounds. A Compilation of Quantitative Solubility Data from the Periodical Literature. N/A
Third Edition, Volume 1, New York, D. Van Nostrand Company Inc
sodium phosphates' various various Thomsen J 1888 N/A Dritter Band. Wassrige Lusung und hydratbildung
various various various Van Wazer JR 1955Structure and properties of the condensed phosphates. X. general structural theory N/A J Am Chem Soc, 77: 6140-6144
various various various Van Wazer JR 1950
Structure and properties of the condensed phosphates. I. some general considerations about phosphoric acids N/A J Am Chem Soc, 72(2): 639-644
various various various Van Wazer JR 1950
Structure and properties of the condensed phosphates. II. A theory of the molecular structure of sodium phosphate glasses N/A J Am Chem Soc 72(2): 644-647
various various various Van Wazer JR 1956Existence of ring phosphates higher than the tetrametaphosphate N/A J Am Chem Soc 78: 1772
Various Various N/A WHO 1970Toxicological evaluation of some extraction solvents and certain other substances Various
FAO Nutrition Meetings Report Series No. 48A. WHO/FOOD ADD/70.39
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-60
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
tripolyphosphate. 'pyrophosphate' Various Various Shannon JE and Lee GF 1966Hydrolysis of condensed phosphates in natural waters N/A Air & Wat. Pollut. Int. J 10, 735-756
Various Various N/A Anon ~2000
Food additives in Europe 2000 - status of safety assessments of food additives presently permitted in the EU. Various Food additives in Europe 2000
Various various Various Bibra Toxicology Advice and Consulting 1993 Phosphoric Acid and Common Inorganic Phosphates various Toxicity Profile.
Various phosphates various various Corbridge DEC 1974 The structural chemistry of phosphorus. N/A Elsevier Scientific Publishing Company.
Various Various Various Federal Register 1985
Phosphates; proposed affirmation of and deletion from GRAS status as direct and human food ingredients. rats Vol 44, No.10, 244
Various various Various GFSA 2008GFSA Online Food Additive Group Details for Phosphates. n/a
Http://www.codexalimentarius.net/gsfaonline/groups/details.html?id=18&lang-en
Various Various Various Jelleff Carr C. 1975Evaluation of the health aspects of phosphates as food ingredients. N/A
Federation of American Societies for Experimental Biology. PB262651.
Various various Various Lewis RJ 2007 Hawley's Condensed Chemical Dictionary N/A Hawley's condensed chemical dictionary, 15th edition.
Various various various Osterheld RK 1972 Nonenzymic hydrolysis at phosphate tetrahedral. N/A
Various Various Various
WHO IPCS INCHEM Toxicological evaluation food additives JECFA no 17
1982
INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY WORLD HEALTH ORGANIZATION TOXICOLOGICAL EVALUATION OF CERTAIN VETERINARY DRUG RESIDUES IN FOOD WHO FOOD ADDITIVES SERIES 17. 1982.
Single superphosphate (SSP)Omoregie E, Ajima MNO, Keke RI and Wieski K 2009
effect of single superphosphate fertiliser on survival and respiratory dynamics of Nile Tilapia, Oreochromis niloticus (Actinopterygh: perciformes:cichildae) Fish Acta Ichthyologica et piscatoria. 39(2): 103-110
No IP substance - refers to Phosphate only
Abdolzadeh A, Wang X, Veneklaas EJ and Lambers H 2010
effects of phosphorous supply on growth, phosphate concentration and cluster-root formation in three Lupinus species plants Annals of Botany. 105:365-374
No IP substance - refers to Phosphate only Ohnishi M and Razzaque MS 2010
Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging mice The FASEB Journal.
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-61
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monoammonium phosphateDe Boer G, Buchanan-Smith JG, Macleod GK & Walton JS 1981
Responses of Dairy Cows Fed Alfalfa Silage Supplemented with Phosphorus, Copper, Zinc, and Manganese cows J Dairy Sci 64:2370-2377
Manganese phosphate (hereaulite) Mn5(PO4)2[PO3(OH)]2.4H2O TESTED AS PART OF A
MIXTURE CONTAINING
MANGANESE SULPHATE 34 18718-07-5Linda A. Beaupre, Fariba Salehi, Joseph Zayed 2004
Physical and Chemical Characterization of MnPhosphate/Sulfate Mixture Used in an Inhalation Toxicology Study n/a Inhalation Toxicology, 16:231–244, 2004
Manganese phosphate' identity not defined 33,34,35
Blumberg H, Shelling DH, Jackson DA 1938 The production of manganese rickets in rats rat The journal of nutrition, 16(3):
manganese hydrogen phosphate 35 51349-94-1F. W. BOYLE, JR., AND W. L. LiNDSAY 1985
Diffraction Patterns and Solubility Products of Several Divalent Manganese PhosphateCompounds n/a SOIL SCI. SOC. AM. J., VOL. 49, PG761-767
manganese hydrogen phosphate 35 51349-94-1F. W. BOYLE, JR., AND W. L. LINDSAY 1986
Manganese Phosphate Equilibrium Relationships in Soils n/a SOIL SCI. SOC. AM. J., VOL. 50,
manganese hydrogen phosphate 35 51349-94-1
David C. Dorman; Karrie A. Brenneman; Anna M. McElveen; Sean E. Lynch; Kay C. Roberts; Brian A.Wong 2002
OLFACTORY TRANSPORT: A DIRECT ROUTE OF DELIVERY OFINHALED MANGANESE PHOSPHATE TO THE RAT BRAIN rat
Journal of Toxicology and Environmental Health, Part A, 65: 20, 1493 — 1511
No IP substances tested
David C. Dorman, Melanie F. Struve, R. Arden James, Marianne W. Marshall, Carl U. Parkinson, and Brian A. Wong 2001
Influence of Particle Solubility on the Delivery of Inhaled Manganeseto the Rat Brain: Manganese Sulfate and Manganese TetroxidePharmacokinetics Following Repeated (14-Day) Exposure rat Toxicology and Applied Pharmacology 170, 79–87
manganese phosphate' (MnPO4) 34 18718-07-5Erikson KM, Shuber RL , Aschner M 2002
Glutamate/Aspartate Transporter (GLAST), Taurine Transporter and Matallothionein mRNA Levels are differentially altered in astrocytes exposed to manganese chlroide, manganese phosphate or manganese sulphate.
Cell cultures derived from rat brains NeuroToxicology 23 281-288
No IP substances tested - MnSO4Erikson, K.M., Dorman, D.C., Lash, L.H., Aschner, M. 2007
Manganese Inhalation by Rhesus Monkeys is Associated with Brain Regional Changes in Biomarkers of Neurotoxicity Rhesus Monkey Tox Sci. 97:459-466.
No IP substances tested - MnSO4Erikson KM, Dorman DC, Lash LH and Ashner M 2008
Duration of airborne-manganese exposure in rhesus monkeys isassociated with brain regional changes in biomarkers of neurotoxicity Rhesus Monkey NeuroToxicology 29 (2008) 377–385
trimanganese bis(orthophosphate) 33 14154-09-7 Heintze SG 1968
Manganese-phosphate reactions in aqueous systems and the effects of applications of monocalcium phosphate on the availablity of manganese to oats in an alkaline fen soil Plant and Soil XXIX, no. 3
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-62
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Manganese phosphate (hereaulite) Mn5(PO4)2[PO3(OH)]2.4H2O TESTED AS PART OF A
MIXTURE CONTAINING
MANGANESE SULPHATE 34 18718-07-5
Fariba Salehi, Daniel Krewski, Donna Mergler, Louise Normandin,Greg Kennedy,Suzanne Philippe, and Joseph Zayeda, 2003
Bioaccumulation and locomotor effects of manganese phosphate/sulfatemixture in Sprague-Dawley rats following subchronic (90 days)inhalation exposure Rat
Toxicology and Applied Pharmacology 191 (2003) 264–271
Manganese phosphate (hereaulite) Mn5(PO4)2[PO3(OH)]2.4H2O TESTED AS PART OF A
MIXTURE CONTAINING
MANGANESE SULPHATE 34 18718-07-5
Fariba Salehi, Louise Normandin, Daniel Krewski, Greg Kennedy, Suzanne Philippe andJoseph Zayed 2006
Neuropathology, tremor and electromyogram in rats exposed to manganese phosphate/sulfate mixture Rat J. Appl. Toxicol. 2006; 26: 419–426
manganese phosphate' (MnPO4) 34 18718-07-5 A. P. Schwab 1989Manganese-Phosphate Solubility Relationships in an Acid Soil n/a Soil Sci. Soc. Am. J. 53:1654-1660 (1989).
No IP substances tested - MnSO4Truong NV, Wilson GL and Andrew CS 1971
MANGANESE TOXICITY IN PASTURE LEGUMES I. EFFECTS OF CALCIUM AND PHOSPHORUSLEVELS IN THE SUBSTRATE n.a Plant and Soil 34, 309-330 (1971)
Tisodium phosphate 4 7601-54-9Czuba M, Zajic A, Poprzecki S, Cholwea J, Woska S 2009
Effects of sodium phosphate loading on aerobic power and capacity in off road cyclists. human Journal of Sports Science and Medicine
various Expert group on vitamins and minerals Secretariat 2003 EVM UK Expert Group Review of Phosphorus N/A EVM Review
ferrous ammonium phosphate N/A 10101-60-7 EFSA
EFSA: Scientific opinion on the safety of ferrous ammonium phosphate as a source of iron added for nutritional purposes to foods for the general population (including food suplements) and to foods for particular nutritional uses. VARIOUS The EFSA Journal 2010; 8(5):1584
phosphoric acid 48 7664-38-2 Kosting PR and Heins C Corrosion of metals by phosphoric acid metals Industrial and Engineering Chemistry. (23)2. pg 140-150
various various Lang K. et al 1958 Condensed Phosphates in Foods N/A Textbook
manganese from all sources 34 n/a
Bouchard MF, Sauve S, Beabeau B, Lengrand M, Brodeur ME, Bouffard T, Limoges E, Bellinger DC and Mergler D
Intellectual impairment in school-age children exposed to manganese from drinking water Children Environmental Health Perspectives. 119(1) 138-143
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-63
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
monocalcium phosphate, dicalcium phosphate, tricalcium phosphate , hydroxyapatite 21,22,24
7758-23-8, 7757-93-9, 1306-06-5 Elliot JC 1994
Structure and chemistry of the apatites and other calcium orthophosphates N/A Studies in inorganic chemistry
sodium fluoride n/a n/aAardema MJ, Gibson DP & LeBoeuf A 1989
Sodium fluoride-induced chromosome aberrations in different stagesof the cell cycle: a proposed mechanism
CellsMutation Research, 223 (1989) 191-203
disodium fluorophosphate (SFP) 47 10163-15-2Baylink DJ, Duane PB, Farley SM & Farley JR 1983
Monophosphate physiology: the effects of fluoride on bone bones Caries Research. 17(1): 56-57
disodium fluorophosphate (SFP) 47 10163-15-2 Broll H, Peichi P, Wlifert H 1990
Effect of sodium monophosphate and calcium on bone density and fracture rate in osteoporosis n/a Lancet. 8: 1446-1447
disodium fluorophosphate (SFP), sodium fluoride 47 10163-15-2
Brun LR, Roma SM, Perez F & Rigalli A 2009
Histological differences in bones of rats treated with sodium fluoride (NaF) and sodium monofluorophosphate (MFP)
rat Bone
sodium fluoride n/a n/a
Bucher JR, Hejtmancik MR, Toft JD, Persing RL, Eustis SL & Haseman JK 1991
Results and conclusions of the national toxicology program's rodent carcinogenicity studies with sodium fluoride rats, mice
Int. J. Cancer: 48, 733-737
disodium fluorophosphate (SFP), sodium fluoride 47 10163-15-2
Delmas PD, Dupuis J, DuBoeuf F, Chapuy MC & Meunier PJ 1990
Treatment of Vertebral Osteoporosis with Disodium Monofluorophosphate: Comparison with Sodium Fluoride human Journal of bone and mineral research. 5(1). 143-147
sodium fluoride n/a n/aDunipace AJ, Zhang W, Noblitt TW, Li Y & Stokey GK 1989
Genotoxicity of fluoride in mouse sperm morphology and micronucleus studies mouse Journal of Dental Research. 68:334
fluoride - unknown source n/a n/a Ekstrand J 1978
Relationship between fluoride in the drinking water and the plasma fluoride concentration in man. human Caries Research. 12: 123-127
disodium fluorophosphate (SFP) 47 10163-15-2 Ericsson Y 1967 Biological splitting of PO3F ions N/A Caries Research. 1: 144-152
oral phosphate' - not specified ? n/a
Broadus AE, Magee JS, Mallette LE, Horst RL, Lang R, Jensen PS, Gertner JM & Baron R 1983
A detailed evaluation of oral phosphate therapy in selected patients with primary hyperparathyroidism Human
Journal of Clinical Endocrinology and Metabolism. 56(5)
sodium fluoride n/a n/a Albanese R 1987
sodium fluoride and chromosome damage (in vitro human lymphocyte and in vivo micronucleus assays) n/a mutagenesis. 2(6): 497-499
disodium fluorophosphate (SFP), sodium fluoride 47 10163-15-2 Brun LR, Pera LI & Rigalli 2010
Bone morphometry and differences in bone fluorine containing compounds in rats treated with NaF and MFP Rat Biomedicine & Pharmacotherapy (64)1-6
disodium fluorophosphate (SFP) 47 10163-15-2 Gron P and Ericsson Y 1983
Caries Research: Monofluorophosphate Perspectives. The compound and its past, present and future applications. various Caries Research. Vol 17, supplement 1
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-64
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
No IP substances: Fluorides Clement Internation Corporation 1993Toxicological profile for fluorides, hydrogen fluoride and fluorine various
Agency for Toxic Substances and Disease Registry. U.S public health service.
disodium fluorophosphate (SFP) 47 10163-15-2 Duff EJ 1983Reaction of monofluorophosphate with apatitic substrates N/A Caries Research 17(1):77-90
disodium fluorophosphate (SFP) 47 10163-15-2 Ericsson Y 1983Monofluorophosphate physiology: General Considerations various Caries Research 17(1): 46-55
Erlacher L, Teufelsbauer H, Bernecker P, Pietschmann P & Weissel M 1993
Comparisons of serum fluoride levels after administration of monofluorophosphate-calcium carbonate or sodium fluoride: differences in peak serum concentrations. Human Clinical Investigations. 72: 1082-1085
rock phosphate N/A N/A Ganegoda GAP & Gunaratne SP 1986
Evaluation of Eppawala rock phosphate as a phosphorus supplement in diets for growing chickens and pigs Chicken and pigs J. Natn. Sci. Coun. Sri Lanka. 14(2):251-260
disodium fluorophosphate (SFP) 47 10163-15-2Gedalia I, Hodge HC, Anaise J, White WE & Menczel J 1970
The effect of sodium monofluorophosphate and sodium fluoride on bone immobilization in rats rat Calc. Tiss. Res. 5, 146-152
defluorinated phosphate Hill WL, Hendricks SB, Jefferson ME & Reynolds DS 1937 Composition of defluorinated phosphate n/a Ind. Eng. Chem., 29(11): 1299-1304
sodium fluoride n/a n/aLi Y, Heerema NA, Dunipace AJ & Stookey GK 1987
Genotoxic effects of fluoride evaluated by sister-chromatid exchange cells Mutation Research. 192: 191-201
disodium fluorophosphate (SFP) 47 10163-15-2 Lindahl CB 1983 Fluoride and monofluorophosphate analysis N/A Caries Research. 17(1): 9-20
disodium fluorophosphate (SFP) 47 10163-15-2 Melberg JR 1983monofluorophosphate utilisation in oral preparations: laboratory observations cells Caries Research. 17(1):102-118
sodium fluoride N/a n/a Mihashi M, Tsutsui T 1996clastogenic activity of sodium fluoride to rat vertebrael body-derived celss in culture cells Mutation Research. 368: 7-13
disodium fluorophosphate (SFP) 47 10163-15-2 Pearce EIF 1983 biochemistry of monofluorophosphate n/a Caries Research. 17(1): 21-35
disodium fluorophosphate (SFP) 47 10163-15-2 Reginster JY 1993
treatment of postmenopausal oseoporosis with sodium monofluorophosphate: preliminary results of a long-term double blind placebo-controlled study Human
proceedings of the forth international symposium on oseoporosis . 452-7
disodium fluorophosphate (SFP) 47 10163-15-2 Ringe JD, Schmidt R 1993Therapeutic experience with the combination monofluorophosphate and calcium Human
proceedings of the forth international symposium on oseoporosis . 433-434
disodium fluorophosphate (SFP) 47 10163-15-2 Rolla G 1983Interaction of monofluorophosphate with plaque and saliva Human Caries Research . 17(1): 91-101
disodium fluorophosphate (SFP) 47 10163-15-2 Smith FA & Hodge HC 1985 Toxicology of monoflurophosphate. rats Caries Research. 17(1): 36-45disodium fluorophosphate (SFP) 47 10163-15-2 White WE 1983 monofluorophosphate - its beginning n/a Caries Research. 17(1): 2-8
disodium fluorophosphate (SFP) 47 10163-15-2 Ericsson Y & Patterson C 1980Studies on the hydrolysis and absorption of monofluorophosphate ions rats , humans Pharmacology and Therapeutics in denistry. 5: 47-54
disodium fluorophosphate (SFP) 47 10163-15-2 Ericsson Y 1973The mechanism of the monofluorophosphate action on hydroxyapatite and dental enamel n/a - human teeth Acta Odont Scand. 21:341-358
disodium fluorophosphate (SFP) 47 10163-15-2 Esteban L, Rigalli A & Puche C 1999
Metabolism of the complex monofluorophosphate-alpha2-macroglobulin in the rat rat Medicina. 59:15-156
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-65
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
disodium fluorophosphate (SFP) 47 10163-15-2Farley JR, Tarbaux NM, Lau KHW &Baylink DJ 1987
monofluorophosphate is hydrolysed by alkaline phosphatase and mimics the actions of NaF on skeletal tissues, In vitro n/a - in vitro study Calcified Tissue International. 40:35-42
various forms of monofluorophosphate - not SFP n/a n/a
Giavaresi G, Fini M, Gnudi S, Nicoli Aldini N, Rocca M, Carpi A & Giardino R 2001
Comparison of calcitonin, alendronate and fluorophosphate effects on ovariectomised rat bone rat Biomed and Pharmacother. 55:397-403
disodium fluorophosphate (SFP) 47 10163-15-2Glass RL, Peterson JK, Zuckerberg DA & Naylor MN 1975
Fluoride ingestion resulting from the use of a monofluorophosphate dentrifice by children human British Dental Journal. 138:423-426
sodium fluoride - NaF n/a n/a Hayashi N & Tsutsiu T 1993
Cell cycle dependenceof cytotoxicity and clastogenicity induced by treatment of synchronized human diploid fibroblasts with sodium fluoride cells Mutation Research. 290:290-302
disodium fluorophosphate (SFP) 47 10163-15-2Haydon GB, Hein JW & Gardner DE 1951
Preliminary investigations of the effect of sodium monofluorophosphate on salivary acid production and hydroxy apatite solubility n/a J Dent Res. 30:466
sodium fluoride - NaF n/a n/a Kanematsu N 1985
Genetic toxicity of biomaterial. 2. DNA damaging effects of sodium fluoride and other fluoride compounds bacteria Jpn. J. Oral Biol. 27: 372-374
sodium fluoride - NaF n/a n/a Khali AM & Da'dara AA 1994
The Genotoxic and Cytotoxic Activities of Inorganic Fluoride in Cultured Rat BoneMarrow Cells cells - rat bone marrow
Archives of Environmental Contamination and Toxicology. 26:60-63
sodium fluoride - NaF n/a n/a Kishi K & Tonomura A Cytogenic effects of sodium fluoride cells unknown
sodium fluoride - NaF n/a n/a Li Y, Dunipace A & Stookey GK 1987Absence of mutagenic and antimutagenic activities of fluoride in Ames Salmonella assays bacteria Mutation Research, 190: 229-236
sodium fluoride - NaF n/a n/a Li Y, Dunipace A & Stookey GK 1987Lack of genotoxic effects of fluoride in the mouse bone-marrow micronucleus test cells - mouse J Dent Res. 66: 1687-1690
sodium fluoride - NaF n/a n/aLi J, Suzuki Y, Hayashi K & Shimizu H 1991 The genotoxic effect of sodium fluoride cells/bacteria Unknown
sodium fluoride - NaF n/a n/aLi Y, Zhang W, Noblitt TW, Dunipace AJ & Stookey GK 1989
Genotoxic evaluation of chronic fluoride exposure: sister-chromatid exchangestudy hamsters Mutation Research, 227 :159-165
disodium fluorophosphate (SFP) 47 10163-15-2Muller P, Schmid K, Warnecke G, Setnikar I & Simon B 1992
Sodium fluoride-induced gastric mucosal lesions: comparison with sodium monofluorophosphate Human Z Gastroenterol. 30:252-254
disodium fluorophosphate (SFP) 47 10163-15-2Nordenberg D, Simkin A, Gedalia I & Robin G 1971
The effect of sodium fluoride and sodium monofluorophosphate on the mechanical properties of normal and osteoporotic rat bone. rat Isr J. Med. Sci . 7(3): 529-531
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-66
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium fluoride - NaF n/a n/a
National Toxicology Program. US Department of Heatlh and Human Services. Public Health Service. National Institute of Health. 1990
Toxicology and carcinogenesis studies of sodium fluoride (CAS No. 7861-49-4) in F344/N rats and B6c3F1 mice (drinking water studies) rats, mice NTP TR-393
sodium fluoride - NaF n/a n/a
Collins T.F.X, Sprando R.L, Black T.N, Shackelford M.E, Bryant M.A, Olejinik N, Ames M.J, Rorie J.I & Ruggles D.I 2001
Multigenerational evaluation of sodium fluoride in rats rats Food and Chemical Toxicology 39, 601-613
sodium fluoride - NaF n/a n/aSprando RL, Collins TFX, Black TN, Rorie J, Ames MJ & O'Donnell M 1997
Testing the potential of sodium fluoride to affect spermatogenesis in the rat RATS Food and Chemical Toxicology. 35:881-890
sodium fluoride - NaF n/a n/a
Collins T.F.X, Sprando R.L, Black T.N, Shackelford M.E, Bryant M.A, Olejinik N, Ames M.J, Rorie J.I & Ruggles D.I 2001
Developmental toxicity of sodium fluoride measured during multiple generations RAT Food and Chemical Toxicology 39, 867-876
sodium fluoride - NaF n/a n/a Heindel J 1994Developmental toxicity of sodium fluoride (CAS #7681-49-4) in Sprague-Dawley (CD) rats RAT NTIS PB95110193
sodium fluoride - NaF n/a n/a Heindel J 1993
Developmental toxicity of sodium fluoride (CAS #7681-49-4) in New Zealand White (NZW) rabbits rabbit NTIS PB94-142684
sodium fluoride - NaF n/a n/a
Collins, TFX, RL Sprando, ME Shackelford, TN Black, MJ Ames, JJ Welsh, MF Balmer, N. Olejnik & DI Ruggles 1995 Developmental toxicity of sodium fluoride in rats rats Food & Chemical Toxicity. 33(1): 951-960
disodium fluorophosphate (SFP) 47 10163-15-2 Rigalli A, Morosano M & Puche RC 1996
Bioavailability of Fluoride Administered as Sodium Fluoride or Sodium Monofluorophosphate to Human Volunteers human Arzneim Forsch / Drug Research. 46(I): 531-533
disodium fluorophosphate (SFP) 47 10163-15-2Rigalli A, Cabrerizo A, Beinlich AD & Puche RC 1994
Gastric and Intestinal Absorption of Monofluorophosphate and Fluoride in the Rat rat Arzneim Forsch / Drug Research. 44: 651-655
disodium fluorophosphate (SFP) 47 10163-15-2Rigalli A, Alloatti R, Menoyo I & Puche RC 1995
Comparative Study of the Effect ofSodium Fluoride and Sodium MonoJluorophosphate on Glucose Homeostasis in the Rat rat Arzneimittelforschung. 45(3): 298-292
disodium fluorophosphate (SFP) 47 10163-15-2Rigalli A, Esteban L, Pera L & Puche RC 1997
Binding of Monofluorophosphate to alpha2-Macroglobulin and C3 n/a Calcified tissue international. 60:86-89
disodium fluorophosphate (SFP) 47 10163-15-2
Rigalli A, Pera L, Morosano M, Masoni A, Bocanera R, Tozzini T & Puche RC 1999
In postmenopausal osteoporosis the bone increasing effect of monofluorophosphate is not dependent on serum fluoride human Medicina. 59:157-161
disodium fluorophosphate (SFP) 47 10163-15-2Rigalli A, Ballina JC, Beinlich AD, Alloatti R & Puche RC 1994
Pharmacokinetic Differences between Sodium Fluoride and Sodium Monofluorophosphate and Comparative Bone Mass Increasing Activity of Both Compounds in the Rat rat Arzneim Forsch/Drug Res. 44(I).6:762766
SFP-calcium carbonate complex n/a n/a Rouveix B, Faurisson F 1988
physiologie et pharmacocinetique du monofluorophosphate disodique-carbonate de calcium human Lettre du Pharmacologue. 2: 1-4
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-67
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
disodium fluorophosphate (SFP) 47 10163-15-2Serbet JL, Richard P, Mennecier I, Bisset JP & Loeb G 1995
Monofluorophosphate Increases Lumbar Bone Density in Osteopenic Patients: A Double-Masked Randomized Study human Osteoporosis Int 5:108-114
sodium fluoride - NaF n/a n/a Spak CJ, Ekstrand J & Zyberstein D 1982Bioavailability of Fluoride Added to Baby Formula and Milk human Caries Res. 16: 249-256
sodium fluoride - NaF n/a n/aTsutsui T, Suzuki N, Ohmori M & Maizumi H 1984
Cytotoxicity, chromosome aberrations and unscheduled DNA synthesis cultured human diploid fibroblasts induced by sodium fluoride cells Mutation Research, 139 193-198
sodium fluoride - NaF n/a n/a Tsutsui T, Ide K & Maizumi H 1984
Induction of unscheduled DNA synthesis in cultured human oral keratinocytes by sodium fluoride cells Mutation Research, 140: 43-48
sodium fluoride - NaF n/a n/a
Tsutsui T, Tanaka Y, Matsudo Y, Uehama A, Someya T, Hamaguchi F, Yamamoto H & Takahashi M 1995
No increases in chromosome aberrations in human diploid fibroblasts following exposure to low concentrations of sodium fluoride for long times cells Mutation Research 335: 15-20
sodium fluoride - NaF n/a n/a Tsutsui T, Suzuki N & Ohmori M 1984
Sodium Fluoride-induced Morphological and Neaplastic Transformation, Chromosome Aberrations, Sister Chromatid Exchanges, and Unscheduled DNA Synthesis in Cultured Syrian Hamster Embryo Cells cells CANCER RESEARCH 44. 938-941.
disodium fluorophosphate (SFP) 47 10163-15-2Van Asten P, Darroudi F, Natarajan AT, Terpstra IJ & Duursma SA 1998
Cytogenetic effects on lymphocytes in osteoporotic patients on long-term fluoride therapy human cells Pharm World Sci. 20: 314-318
disodium fluorophosphate (SFP) 47 10163-15-2Villa A, Guerrero S, Cisternas P & Mockeberg F 1989
Fluoride Bioavailability from Disodium Monofluorophosphate Fluoridated Milk in Children and Rats human, rats Caries Research. 23:179-183
hydrogen fluoride only tested n/a n/aVoroshilin SI, Plotko EG, Gatiyatullina EZ & Gileva EA 1973
Cytogenetic effect of inorganic fluorine compunds on human and animal cells in vivo and in vitro cells: human/animal Sov Genet. 9:492-496
disodium fluorophosphate (SFP) 47 10163-15-2 Zeiger E, Shelby MD & Witt KL 1993 Genetic toxicity of fluoride variousEnvironmental and Molecular Mutagenesis 21:309-318
disodium fluorophosphate (SFP) 47 10163-15-2 DePaola PF 1983Clinical Studies of Monofluorophosphate Dentifrices various Caries Res. 17 (1): 119-135
hydroxyapatite 24 1306-06-5Avnimelech Y, Moreno EC & Brown WE 1972
Solubility and surface properties of finely divided hydroxyapatite n/a
Journal of Research of then Nation Bureau of Standards A. Physics and Chemistry. 77A. 1: 149-155
calcium phosphate unspecified n/a n/a Bassett H 1958The phosphate of calcium. Part V. Revision of the earlier space diagram n/a Journal of the Chemistry. 2949-2955
disodium hydrogenorthophosphate 3 7558-79-4Bouchoud L, Fonzo-Christie C, Sadeghipour F & Bonnabry P 2010
Maximizing calcium and phosphate content in neonatal parenteral nutrition solutions using organic calcium and phosphate salts n/a
Journal of Parenteral and Enteral Nutrition. 34(5): 542-545
sodium phosphate (unspecified - states neutral buffered)
Cade R, Conte M, Zauner C, Mars D, Peterson J, Lunne D, Hommen & Packer D 1984
Effects of phosphate loading on 2,3-diphosphoglycerate and maximal oxygen uptake human
Medicine and Science in Sprots and Exercise. 18(3): 263-266
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-68
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
phosphoric acid 48 7664-38-2 Inco 1966Corrosion resistance of nickel-containing alloys in phosphoric acid n/a Corrosion Engieneering Bulletin. 4. 1-40
phosphoric acid 48 7664-38-2 Craig BD 1990 Handbook of Corrosion Data n/a n/a
sodium dihydrogenorthophosphate (MSP) 2 7558-80-7 Duguid JB 1938 The primary lesion in phophate nephritis rat
Journal of Pathology and Bacteriology. 43(2): 321-326
phosphoric acid 48 7664-38-2 Ebling HF & Scheil MA 1951A standard laboratory corrosion test for metals in phosphoric acid service n/a Transactions of the ASME. 975-987
phosphoric acid 48 7664-38-2Guenbour A, Hajji MA, Jallouli EM and Bachir AB 2006
Study of corrosion–erosion behaviour of stainless alloys in industrial phosphoric acid medium n/a Applied Surface Science. 253: 2362-2366
potassium dihydrogenorthophosphate, dipotassium hydrogenorthophosphate 12, 13 7778-77-0
Goldsmith RS, Jowsey J, Dube WJ, Riggs BL, Arnaud CD & Kelly PJ 1976
Effects of phosphorus supplementation on serum parathyroid hormone and bone morphology in osteoporosis human
Journal of clinical Endocrinology and Metabolism. 43(3): 523-532
tricalcium bis(orthophosphate) (ß-TCP) 23 7758-87-4
Gregory TM, Moreno EC, Patel JM & Brown WE 1974
Solubility of β-Ca3(PO4)2 in the system Ca(OH)2-H3PO4-H2O at 5, 15, 25 and 37°C n/a
Journal of Research of the National Bureau of standards. A. Physics and Chemistry. 78A(6):
phosphoric acid 48 7664-38-2Groves ND, Eisenbrown CM & Sharfstein LR 1960
Corrosion of metals by weak acids under heat transfer conditions n/a
Corrosion - National association of corrosion engineers. Vol 17. 173-176
tricalcium bis(orthophosphate) (ß-TCP), calcium hydrogenorthophosphate (DCP) 23, 22 7758.87-4 Holt LE, Lamer VK & Chown HB 1925
Studies in calcification. 1. the solubility product of secondary and tertiary calcium phosphate under various conditions n/a Journal of Biological Chemistry: 64: 509-1925
calcium hydrogenorthophosphate (DCP), hydroxyapatite 22, 24 7757-93-9 Ishikawa K & Eanes ED 1993
The hydrolysis of anhydrous dicalcium phosphate in hydroxyapatite n/a Journal of Dental Research. 72(2): 474-480
Hydroxyapatite (HAP) 24 1306-06-5 Levinskas GJ & Neuman WF 1954The solubility of bone mineral. I solubility studies of synthetic hydroxylapatite. n/a Journal of chemistry. C. 59. 164-169
phosphoric acid 48 7664-38-2 Multi Alloy n/a Lab corrosion data for stainless steel. n/a Multi-alloy
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-69
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium fluoride n/a n/aMaurer JK, Cheng MC, Boysen BG & Anderson RL 1990
Two-year carcinogenicity study of sodium fluoride in rats rat
Journal of the National Cancer Institute. 82(13): 1118-1126
calcium hydrogenorthophosphate (DCP) 22 7757-93-9
MCDowell H, Brown WE & Sutter JR 1971
Solubility of calcium hydrogen phosphate. Ion-pair formation. n/a Inorganic Chemistry. 10(8):1638-1643
hydroxyapatite 24 1306-06-5 Misra DN 1982Adsorption on and surface chemistry of hydroxyapatite n/a textbook: Plenum Press
calcim hydrogenorthophosphate, tricalcium phosphate 22, 23 7757-93-9 Monma H 1980
Preparation of octacalcium phosphate by thehydrolysis of α- tricalcium phosphate n/a Journal of Materials Science.15:2428-2434
calcium hydrogenorthophosphate 22 7757-93-9Moreno EC, Gregory TM & Brown WE 1966
Solubility of CaHPO4.2H2O and the formation of ion pairs in the system Ca(OH)2-H3PO4-H20 at 37.5°C n/a
Journal of Research of the National Bureau of Standards - A. Physics and Chemistry. 70(A),6: 545-553
hydroxyapatite 24 1306-06-5Moreno EC, Gregory TM & Brown WE 1968 Preparation and solubility of hydroxyapatite n/a
Journal of Research of the National Bureau of Standards - A. Physics and Chemistry. 72(A),6: 545-554
phosphoric acid 48 7664-38-2 Morgan AR 1959Corrosion of types 316 and 317 Stainless steel by 75% and 85% phosphoric acid n/a
corrosion - national association of corrosion engineers. Vol 15: 351-354
phosphate' n/a n/a Nordin EC Phosphorus n/a Journal of Food and Nutrition. 45:3. 61-75
calcium hydrogenorthophosphate 22 7757-93-9 Patel PR, gregory TM & Brown WM 1974Solubility of CaHPO4.2H2O in the quaternary system Ca(OH)2-H3PO4-NaCl-H2O at 25°C n/a
Journal of Research of the National Bureau of Standards. A -Physics and Chemistry. 78(A).6: 675-682
hydroxyapatite 24 1306-06-5 Pearce EIF 1988Letters to the editor: On the dissolution of hydroxyapatite in acids n/a Journal of Dental Research. 67(7): 1056-1058
disodium hydrogenorthophosphate 3 7558-79-4 Prinzivalli M & Ceccarelli S 1999
sodium d-fructose-1,6-diphosphate vs. sodium monohydrogenphosphate in total parenteral nutrition: a comparative in vitro assessment of calcium/phosphate compatibility n/a
Journal of parenteral and Enteral Nutrition. 23(6): 235-242
phosphoric acid 48 7664-38-2 Renshaw WG & Lula RA 1956The corrosion properties of chrominum-nickel-manganese austenitic stainless steels n/a
Proceedings - American Society for testing and Materials. 52: 866
hydroxyapatite 24 1306-06-5 Saleeb FZ & De Bruyn PL 1972 Surface properties of alkaline earth apatites n/aJournal of Electroanalytical Chemistry and Interfacial Electrochemistry. 37: 99 - 118
tricalcium bis(orthophosphate) 23 7758.87-4 Sanderson PH 1958Functional Aspects of Renal Calcification in Rats rat Clinical Science. 18:67-79
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-70
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
octacalcium phosphate n/a n/aShyu LJ, Perez L, Zawacki SJ, Heughebaert JC & Nancollas GH 1983
The solubility of octacalcium phosphate at 37 °C in the system Ca(OH)2-H3PO4-KNO3-H2O n/a Journal of Dental Research . 62: 398-400
inorganic phosphate n/a n/aTakeda E, Taketani Y, Sawada N, Sato T & Yamamoto H 2004
The regulation and function of phosphate in the human body n/a Biofactors 21. 345-355
phosphate' n/a n/aTenenhouse HS, Martel J, Rubin J & Harvey N 1994
Effect of phosphate supplementation on the expression of the mutant phenotype in murine x-linked hypophosphatemic rickets. mice Bone. 15(6): 677-683
hydroxyapatite 24 1306-06-5Verbeek RMH, Steyaer H, Thun HP & Verbeek F 1980 Solubility of synthetic calcium hydroxyapatites n/a Faraday discussions. 1(76): 209-219
phosphoric acid 48 7664-38-2 Warren D 1960Corrosion and weldability studies on chromium-manganese austenitic stainless steels n/a
corrosion - National Association of Corrosion Engineers. 16: 101-112
hydroxyapatite 24 1306-06-5 Wier D R, Chien SH & Black CA 1971 Solubility of hydroxyapatite n/a Soil Science. 111(2): 107 - 112
hydroxyapatite 24 1306-06-5Wu MS, Higuchi WI, Fox JL & Friendman M 1967
Kinetics and mechanism of hydroxyapatite crystal dissolution in weak acid buffers using the rotating disk method. n/a Journal of Dental Researc. 55(3): 496-505
phosphoric acid 48 7664-38-2 Yaro AS, Wael RK & Khadom AA 2010Reaction kinetics of corrosion of mild steel in phosphoric acid n/a
Journal of the University of Chemical Technology and Metallurgy. 45(4): 443-448
disodium fluorophosphate (SFP) 47 10163-15-2Beinlich AD, Brun LRM, Rigalli A & Puche RC 2003
Intestinal absorption of disodium monofluorophosphate in the rat as affected by concurrent administration of calcium. rat ArzneimForschDrugRes. 53(8):584-589
disodium fluorophosphate (SFP) 47 10163-15-2 Trautner K & Einwag J 1989Influence of milk and food on fluoride bioavailability from NaF and Na2FPO3 in man. human Journal of Dental Research. 68: 72-77
disodium fluorophosphate (SFP) 47 10163-15-2
Van Asten P, Duursma, Glerum JH, FFT Ververs, Van Rijn HJM & Van Dijk A 1996
Absolute bioavailability of fluoride from disodium monofluorophosphate and enteric-coated sodium fluoride tablets human Wur J Clinical Pharmacol. 50: 321-326
disodium fluorophosphate (SFP) 47 10163-15-2Villa A, Carrasco G, Valenzuela A & Garrido A 1992
The effect of calcium on disodium monofluorophosphate absorption from the gastrointestinal tract of the rat rat
Research Communications in Clinical Pathology and Pharmacology. 77(3): 367-373
glutamine monofluorophosphate n/a n/a Warneke G, Setnikar I 1993
Biavailability and pharmacokinetics of fluoride from two glutamine monofluorophosphate preparations human ArzneimForschDrugRes. 43(I).5:584-588
disodium fluorophosphate (SFP) 47 10163-15-2 Warneke G & Setnikar I 1993Effects of meal on the pharmacokinetics of fluoride from oral monofluorophosphate human Arzneim-Forsch/Drug res. 43(I).5: 590-595
phosphoric acid 48 7664-38-2Elmore KL, Hatfield JD, Dunn RL & Jones AD 1965
dissociation of phosphoric acid solutions at 25 °C n/a The journal of physical chemistry . 69(10): 3520-3525
phosphoric acid 48 7664-38-2 Kreysa G and Shutze M
Corrosion Handbook. Corrosive agents and their interaction with materials. Volume 3. hypochlorites, phosphoric acid. n/a Handbook. ISBN: 3-527-31119-X
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-71
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
sodium tetraborate and boric acid n/a n/aSoucek D, Dickenson A and Koch BT 2011
Acute and chronic toxicity of boron to a variety of fresh water organisms various
Environmental Toxicology and Chemistry, Vol. 30, No. 8, pp. 1906–1914,
mixture: monosodium phosphate and disodium phosphate 2,3 n/a Brunelli SM 2009
Association Between Oral Sodium Phosphate Bowel Preparations and Kidney Injury: A Systematic Review and Meta-analysis human
American Journal of Kidney Diseases, Vol 53, No 3 (March), 2009: pp 448-456
sodium phosphate' - likely to be a mixture of MSP and DSP 2,3? n/a
Seol DC, Hong SN, Kim JH, Sung IK, Park HS, Lee Jh and Shim CS 2010
Change in renal function after sodium phosphate preparation for screening colonoscopy human
World Journal of Gastroenterology (2010) April 28; 16(16): 2010-2016
sodium phosphate' - likely to be a mixture of MSP and DSP 2,3? n/a
Juluir R, Eckhart G and Imperiale TF 2011
Polyethylene glycol vs. sodium phosphate forbowel preparation: A treatment arm metaanalysis of randomized controlled trials human BMC Gastroenterology 2011, 11:38
sodium phosphate' - likely to be a mixture of MSP and DSP 2,3? n/a
Markowitz GS, Stokes MB, Radhakrishnan J,and D’Agati VD 2005
Acute Phosphate Nephropathy following Oral Sodium Phosphate Bowel Purgative: An Underrecognized Cause of Chronic Renal Failure human J Am Soc Nephrol 16: 3389–3396, 2005
monocalcium phosphate, dicalcium phosphate 21, 22 7758-23-8
Ellam T, Wilkie M, Chamerlain J, Crossman D, Eastell R, Francis S and Chico TJA 2001
Dietary Phosphate Modulates Atherogenesis and Insulin Resistance in Apolipoprotein E Knockout Mice Mice
Arteriosclerosis, Thrombosis and vascular biology. 2011:31
monocalcium phosphate (MCP) 21 7758-23-8 Morgareidge K 1974
Teratologic evaluation of FDA 71-81, (monocalcium phosphate; monohydrate) in mice, rats and rabbits rats/mice NTIS PB234866
SODIUM ACID PYROPHOSPHATE 5 7758-16-9 Morgareidge K 1973Teratologic evaluation of FDA 71-61, (sodium acid pyrophosphate) rats/mice NTIS PB22381
sodium tripolyphosphate 0 7758-29-4 Morgareidge K 1973Teratologic evaluation of FDA 71-46 (sodium tripolyphosphate, anhydrous) rats/mice FDABF-GRAS-075
monopotassium phosphate 12 7778-77-0Naddy RB, Tapp K, Rehner AB, Pillard DA, Schrage L 2011
Identifying the cause of toxicity in an algal whole effluent toxicity study –An unanticipated toxicant algae Chemosphere 85 (2011) 1026–1032
various inorganic polypjosphates n/a n/aTatyana V. Kulakovskaya, Vladimir M. Vagabov, Igor S. Kulaev 2010
Inorganic polyphosphate in industry, agriculture and medicine: modern state and outlook n/a Process biochemistry
polyphosphates n/a n/a Andreeva NA & Okorokov 1993
Purification and Characterization of Highly Active and Stable Polyphosphatase from Saccharomyces cerevisiae Cell Envelope yeast (S.cerevisiae) YEAST VOL. 9: 127-1 39
Inorganic linear polyphosphate
Leyhausen G, Lorenz B, Zhu H, Geurtsen W, Bohnensack R, Muller WEG & Schroder HC 1998
Inorganic Polyphosphate in Human Osteoblast-like Cells n/a - cells
JOURNAL OF BONE AND MINERAL RESEARCHVolume 13, Number 5, 1998
Inorganic polymeric phosphate/polyphosphate n/a n/a
Muller WEG, Wang X, Diehl-Seifert B, Kropf K, Schlossmacher U, Lieberwirth I, Glasser G, Weins M & Schroder HC 2011
Inorganic polymeric phosphate/polyphosphate as an inducer of alkaline phosphatase and a modulator of intracellular Ca2+ level in osteoblasts (SaOS-2 cells) in vitro Acta Biomaterialia 7 (2011) 2661–2671
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-72
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
inorganic polyphosphate n/a n/a
Y. Hacchou, T. Uematsu, O. Ueda, Y. Usui, S. Uematsu, M. Takahashi, T. Uchihashi, Y. Kawazoe, T. Shiba, S. Kurihara, M. Yamaoka and K. Furusawa 2007
Inorganic Polyphosphate: a Possible Stimulant of Bone Formation n/a J DENT RES 2007 86: 893
inorganic polyphosphates n/a n/a Lorenz B & Schroder HC 2001Mammalian intestinal alkaline phosphatase acts as highly active exopolyphosphatase n/a Biochimica et Biophysica Acta 1547 (2001) 254-261
inorganic polyphosphate n/a n/a
Lubov Ryazanova, Nadeschda Andreeva, Tatiana Kulakovskaya, Airat Valiakhmetov, Valerii Yashin, Vladimir Vagabov, Igor Kulaev 2011
The early stage of polyphosphate accumulation in Saccharomyces cerevisiae: comparative study by extraction and DAPI staining yeast (S.cerevisiae)
Advances in Bioscience and Biotechnology, 2011, 2, 293-297
inorganic polyphosphate n/a n/a
Y. Kawazoe, T. Shiba, R. Nakamura, A. Mizuno, K. Tsutsumi, T. Uematsu, M. Yamaoka, M. Shindoh and T. Kohgo 2004
Induction of Calcification in MC3T3-E1 Cells by Inorganic Polyphosphate n/a J DENT RES 2004 83: 613
potassium dihydrogenorthophosphate 12 7778-77-0
Matsuzaki H, Katsumata S, Uehara M, Uehara M, Nakamura K &Suzuki K 2002
Sex differences in kidney mineral concentrations and urinary albumin excretion in rats given high-phosphorus feed. rat Biosci. Biotechnol. Biochem 66(8): 1737-1739
inorganic diphosphate, triphosphate n/a n/a Yoza N, Onoue S & Kuwahara Y 1997
Catalytic ability of alkaline phosphatase to promote P-O-P bond hydrolyses of inorganic diphosphate and triphosphate n/a
Chemical society of Japan. Chemistry letters. 491-492
phosphate n/a n/aKaneko H, Shimada A & Hirayama K
Short-term algal toxicity test based on phosphate uptake algae Water Research 38 (2004) 2173–2177
potassium dihydrogenorthophosphate 12 7778-77-0 Atuah L & Hodson ME 2011
A comparison of the relative toxicity of bone meal and other P sources used as remedial treatments to the earthworm Eisenia fetida earthworm Pedobiologia. Article in press,
Magnesium phosphate cement n/a n/a
Yu Y, Wang J, Liu C, Zhang B, Chen H, Guo H, Zhong G, Qu W, Jiang S & Huang H 2010
Evaluation of inherent toxicology and biocompatibility of magnesium phosphatebone cement n/a Colloids and Surfaces B: Biointerfaces 76 : 496–504
rock phosphate n/a n/a Condor JM, Lanno RP & Basta NT 2001Assessment of Metal Availability in Smelter Soil Using Earthworms and Chemical Extractions earthworm J. Environ. Qual. 30:1231–1237
diammonium phosphate 19 7783-28-0Azizullah A, Nasir A, Richter P, Lebert M & Hader DP 2010
Evaluation of the adverse effects of two commonly used fertilizers, DAP and urea,on motility and orientation of the green flagellate Euglena gracilis Euglena gracilis
Environmental and Experimental Botany 74: 140– 150
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-73
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
inorganic phosphate' in vivo n/a n/a Kuro-o M 2010A potential link between phosphate and aging—Lessons from Klotho-deficient mice mice
Mechanisms of Ageing and Development 131 : 270–275
bone ash 24 68439-86-1 Davis NA, Hodson ME & Black S 2002
Changes in toxicity and bioavailability of lead in contaminated soils to the earthworm Eisenia fetida (Savigny 1826) after bone meal amendments to the soil. earthworm
Environmental Toxicology and Chemistry, Vol. 21, No. 12,:2685–2691
Triple Super Phosphate n/a n/a Gouider M, Feki M & Sayadi S 2010
Bioassay and use in irrigation of untreated and treated wastewaters from phosphate fertilizer industry plants Ecotoxicology and Environmental Safety 73:932–938
phosphate n/a n/a Ohnishi M, Kato S & Razzaque MS 2011
Genetic induction of phosphate toxicity significantly reduces the survivalof hypercholesterolemic obese mice mice
Biochemical and Biophysical Research Communications xxx (2011) xxx–xxx Article in press.
potassium dihydrogenorthophosphate 12 7778-77-0
Maenpaa KA, Kukkonen JVK & Lydy MJ 2002
Remediation of Heavy Metal-Contaminated Soils Using Phosphorus: Evaluationof Bioavailability Using an Earthworm Bioassay earthworm Arch. Environ. Contam. Toxicol. 43, 389–398
phosphoric acid 48 7664-38-2Fettman MJ, Coble JM, Hamar DW, Norrdin RW 1992
Effect of dietary phosphoric acid supplementation on acid-base balance and mineral and bone metabolism in adult cats cat Am J Vet Res, 53(11): 2125-2135
phosphoric acid, dicalcium phosphate 48, 22 7664-38-2Ibrahim S, Fisher C, El Alaily H, Soliman H and Anwar A 1988
Improvement of the nutritional quality of Egyptian and Sudanese sorghum grains by the addition of phosphates chicks British Poultry Science. 29: 721-728
dicalcium phosphate 22 7757-93-9 Potter LM, Potchanakorn M, Ravindran V and Kornegay ET 1995
Bioavailability of phosphorus in various phosphate sources using body weight and toe ash as response criteria chicks Poultry Science. 74: 813-820
phosphoric acid, monocalcium phosphate monohydrate, dipotassium phosphate 48, 21, 22 7664-38-2
Ravindran V, Kornegay ET, Potter LM, Ogunabameru BO, Welten MK, Wilson JH and Potchanakorn M 1995
An Evaluation of Various Response Criteria in Assessing Biological Availability of Phosphorus for Broilers chicks Poultry Science. 74: 1820-1830
Manganese oxide, Manganese sulphate, Trimanganese tetraoxide, Manganese phosphate (hureaulite) (MMangP) 34 18718-07-5
Dorman DC, Struve MF, Clewell HJ III and Anderson ME 2006
Application of pharmacokinetic data to the risk assessment of inhaled manganese Rat, human NeuroToxicity, 27: 752-764
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-74
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Manganese phosphate (hureaulite) (MMangP) 34 18718-07-5
Dorman DC, Struve MF, Marshall MW, Parkinson CU, James RA, and Wong BA 2006
Tissue manganese concentrations in young male rhesus monkeys following subchronic manganese sulfate inhalation Monkey Toxicological Sciences, 92(1): 201-210
Manganese phosphate (hureaulite) (MMangP) 34 18718-07-5
Dorman DC, McManus BE, Marshall MW, James RA and Struve MF 2004
Old age and gender influence the pharmacokinetics of inhaled manganese sulfate and manganese phosphate in rats Rat Toxicology and Applied Pharmacology, 197: 113-124
No IP substances: SrMn2(PO4)2 and Β'-Mn3(PO4)2 N/A N/A
El-Bali B, Boukhari A, Glaum R, Gerk M and Maaß K 2000
Contributions on crystal structures and thermal behaviour of anhydrous phosphates XXIX - Preparation and structure determination of SrMn2(PO4)2 and Β'-Mn3(PO4)2 N/A
Zeitschrift für anorganische und allgemeine Chemie, 626(12): 2557-2562
Manganese phosphate (hureaulite) (MMangP) - Mn5(HPO4)2(PO4)2.4H2O 34 18718-07-5 Gerault Y, Riou A and Cudennec Y 1987
Phosphate hydrogénophosphate hydrate de
manganèse N/A Acta Cryst. C43: 1829-1830
No IP substances: Mn (unspecified) N/A N/A Gwiazda R, Lucchini R and Smith D 2007
Adequacy and consistency of animal studies to evaluate the neurotoxicity of chronic low-level manganese exposure in humans Rodent, primate
Journal of Toxicology and Environmental Health, Part A, 70(7)
Various phosphates N/A N/A Huminicki DMC and Hawthorne FC 2002The Crystal Chemistry of the Phosphate Minerals N/A
Reviews in Mineralogy and Geochemistry, 48: 123-253
Manganese phosphate (hureaulite) (MMangP) - Mn5(HPO4)2(PO4)2.4H2O 34 18718-07-5 Unknown 2005? Huréaulite Mn52+(HPO4)2(PO4)2.4H2O N/A Handbook of Mineralogy
Manganese phosphate (hureaulite) (MMangP) - (Mn,Fe)5(PO4)2(HPO4)2.4H2O 34 18718-07-5 Unknown ? Hureaulite N/A
http://www.mindat.org/min-1952.html [accessed 21 Oct 2011]
Manganese orthophosphate 33 14154-09-7Massa W, Yakubovich OV and Dimitrova OV 2005
A novel modification of manganese orthophosphate Mn3(PO4)2 N/A Solid State Sciences, 7: 950-956
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-75
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Hureaulite - Mn52+(H2O)4[PO3(OH)]2[PO4]2 34 18718-07-5 Moore PB and Takahuru A 1973
Hureaulite, Mn52+(H2O)4[PO3(OH)]2[PO4]2: Its atomic arrangement N/A American Mineralogist, 58: 302-307
Manganese phosphate (hureaulite) Mn5(PO4)2(PO3(OH))2.4H2O, 34 18718-07-5
Normandin L, Beaupré, Salehi F, St-Pierre A, Kennedy G, Mergler D, Butterworth RF, Philippe S and Zayed J 2004
Manganese distribution in the brain and neurobehavioural changes following inhalation exposure of rats to three chemical forms of manganese Rat NeuroToxicology, 25: 433-441
Manganese phosphate (hureaulite) Mn5(PO4)2(PO3(OH))2.4H2O 34 18718-07-5
Sistrunk SC, Ross MK and Filipov NM 2007
Direct effects of manganese compounds on dopamine and its metabolite Dopac: an in vitro study Rat
Environmental Toxicology and Pharmacology, 23: 286-296
No IP substances investigated - NaCl N/A N/A Eaton LJ, Hoyle J and King A 1999Effects of deicing salt on lowbush blueberry flowering and yield N/A Canadian Journal of Plant Science, 79: 125-128
No IP substances investigated - NaCl and KCl N/A N/A Freitas EC and Rocha O 2011
Acute and chronic effects of sodium and potassium on the tropical freshwater cladoceran Pseudosida ramosa Crustacean Ecotoxicology, 20: 88-96
No IP substances investigated - NaCl and sea water N/A N/A
El-Deeb Ghazy MM, Habashy MM, Kossa FI and Mohammady EY 2009
Effects of salinity on survival, growth and reproduction of the water flea, Daphnia magna Crustacean Nature and Science, 7(11): 28-42
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-76
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
No IP substances investigated - NaCl N/A N/AMartínez-Jerónimo F and Martínez-Jerónimo L 2007
Chronic effect of NaCl salinity on a freshwater strain of Daphnia magna Straus (Crustacea: Cladocera): A demographic study Crustacean Ecotoxicology and Environmental Safety, 67: 411-416
No IP substances investigated - NaCl N/A N/ANielsen DL, Brock MA, Rees GN and Baldwin DS 2003
Effects of increasing salinity on freshwater ecosystems in Australia N/A Australian Journal of Botany, 51: 655-665
No IP substances investigated - KCl and potassium acetate (KC2H3O2) N/A N/A Utz LRP and Bohrer MBC 2001
Acute and chronic toxicity of potassium chloride (KCl) and potassium acetate (KC2H3O2) to Daphnia similis and Ceriodaphnia dubia (Crustacea; Cladocera) Crustacea Bull Environ Contam Toxicol, 66: 379-385
No IP substances investigated - NaCl and CaCO3 N/A N/A Cowgill UM and Milazzo DP 1990
The sensitivity of two cladocerans to water quality variables: salinity and hardness Crustacea Arch Hydrobiol, 120(2): 185-196
Phosphorus (unspecified) N/A N/ADodds WK, Carney E and Angelo RT 2006
Determining ecoregional reference conditons for nutrients, secchi depth and chlorophyll a in Kansas lakes and reservoirs
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-77
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Phosphate (unspecified), orthophosphate, polyphosphate, phosphorus (unspecified), P2O5 N/A N/A
Crouzet P, Nixon S, Rees Y, Parr W, Laffon L, Bøgestrand J, Kristensen P, Lallana C, Izzo G, Bokn T, Bak J, Lack TJ and Thyssen N (Ed) 1999 Nutrients in European ecosystems
Phosphorus (unspecified), orthophosphate N/A N/A European Environment Agency ? Nitrogen and phosphorus in rivers Indicator fact sheet (WEU02)
Phosphorus (unspecified) N/A N/A Filippelli GM 2008The global phosphorus cycle: past present and future Elements, 4:89-95
Calcium, magnesium, sodium, potassium, ammonium, sulfate, nitrate, chloride, orthophosphate, hydrogen, bicarbonate, hydroxide N/A N/A
National Atmospheric Deposition Program 1991
Quality assurance report NADP/NTN deposition monitoring
Various (Ca2+, Mg2+, Na+, K+, Cl-, SO42-, HCO3-, SiO2) N/A N/A Meybeck M 2003 Global occurrence of major elements in rivers
Treatise on Geochemistry : Surface and Ground Water, Weathering, and Soils, Elsevier Ltd, ISBN: 0-08-044340-0 pages 207–223
Various (S, Na, K, N, P) N/A N/A Meybeck M and Helmer R 1989The quality of rivers: from pristine stage to global pollution
Palaeogeography, Palaeoclimatology, Palaeoecology (Global and Planetary Change Section), 75: 283-309
Ferrous phospate 27 10045-86-0Aguilar F, Charrondiere UR, Dusemund B et al 2009
Scientific Opinion of the Panel on Food Additives and Nutrient Sources added to Food on a request from the European Commission on Ferrous phosphate added for nutritional purposes to food supplements. The EFSA Journal, 951: 1-13
Phosphorus N/A N/A Solheim AL (Ed) 2005 Reference conditions of European Lakes REBECCA Project (draft paper)
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-78
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
No IP substances investigated - CaC03 N/A N/A World Health Organisation 2003
Hardness in drinking water; Background document for development of WHO guidelines for drinking-water quality
Originally published in Guidelines for drinking water quality, 2nd ed, Vol 2, Health criteria and other supporting information, World Health Organisation, Geneva, 1996
No IP substances investigated N/A N/A Beck GR Jr, Zerler B and Moran E 2000Phosphate is a specific signal for induction of osteopontin gene expression PNAS, 97(15): 8352-8357
Phosphate (unspecified) N/A N/A
Camalier CE, Young MR, Bobe G, Perella CM, Colburn NH and Beck GR Jr 2010
Elevated phosphate activates N-ras and promotes cell transformation and skin tumorigenesis Cancer Prev, 3(3): 359-370
Phosphate (unspecified) N/A N/A
Xu C-X , Jin H, Lim H-T, Ha Y-C, Chae C-H, An G-H, Lee K-H and Cho M-H 2010
Low dietary inorganic phosphate stimulates lung tumorigenesis through altering protein translation and cell cycle in K-rasLA1 mice Nutrition and Cancer, 62(4): 525-532
Phosphate (unspecified) N/A N/A Jin H et al 2009High dietary inorganic phosphate increases lung tumorigenesis and alters Akt signaling Am J Respir Crit Care Med, 179: 59-68
Phosphate (unspecified) N/A N/A Kapur S 2000A Medical Hypothesis: Phosphorus Balance and Prostate Cancer Cancer Investigation, 18(7): 664-669
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-79
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Phosphate (unspecified) N/A N/A
Giovannucci E, Rimm EB, Wolk A, Ascherio A, Stampfer MJ, Colditz GA and Willett WC 1998
Calcium and fructose intake in relation to risk of prostate cancer Cancer Research, 58: 442-447
Phosphate (unspecified) N/A N/A Elser J
2007 and 2010
Stoichiometry and the New Biology: The Future Is Now
PLoS Biology www.plosbiology.org , 5(7): 1403-1405 and Biological Stoichiometry in Human Cancer, PLoS ONE, www.plosone.org, 10: 1-7
Phosphate (unspecified) N/A N/A Borrell B 2010 Elemental shortage The Scientist, 24(11): 46
Monobasic sodium phosphate (NaH2PO4) and dibasic sodium phosphate (Na2HPO4) 2, 3
7558-80-7, 7558-79-4 Conrads KA, Yi M, Simpson KA et
al 2005
A combined proteome and microarray investigation of inorganic phosphate-induced pre-osteoblast cells Mol Cell Proteomics, 4: 1284-1296
Phosphate (unspecified) N/A N/A Elser JJ, Nagy JD and Kuang Y 2003Biological stoichiometry: an ecological perspective on tumor dynamics BioScience, 53(11): 1112-1120
Phosphorus N/A N/AElser JJ, Kyle MM, Smith MS and Nagy JD 2007 Biological stoichiometry in human cancer
PLoS ONE 2(10): e1028. doi:10.1371/journal.pone.0001028
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-80
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Phosphate (unspecified) N/A N/A Engström W and Zetterberg A 1983
Phosphate and the regulation of DNA replication in normal and virus transformed 3T3 cells Biochem J, 214: 695-702
Phosphate (unspecified) N/A N/A Anon 2009
Statement of the International Food Additives Council and the European Chemical Industry Council on Jin et al "High Dietrary Inorganic Phosphate Increases Lung Tumorigenesis and Alters Akt Signaling"
http://www.slideshare.net/changezkn/summary-5553163 [accessed 29 March 2012]
Phosphate (unspecified) N/A N/A Laws JO and Strickland LH 1962The rate of changes of inorganic phosphate content of Ehrlich Ascites-Tumour cells Biochem J, 83: 84-91
No IP substances investigated N/A N/A EFSA 2004
Opinion of the scientific panel on dietetic products, nutrition and allergies on a request from the commission related to the tolerable upper intake level of iron The EFSA Journal, 125, 1-34
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-81
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
SALP acidic and SALP basic 43 7785-88-8 EFSA 2011Statement on the evaluation of a new study related to the bioavailability of aluminium in food The EFSA Journal, 9(5): 2157
Manganese (unspecified) N/A N/AAschner M, Erikson KM and Dorman DC 2005
Manganese dosimetry: species differences and implications for neurotoxicity Critical Reviews in Toxicology, 35:1-32
Phosphoric acid 48 7664-38-2 Sweet DV1985-1986 58663. Phosphoric Acid
National Institute for Occupational Safety and Health, Registry of Toxic Effects of Chemical Substances, Volume 4
Aluminium hydroxide N/A N/AAndreoli SP, Bergstein JM, Sherrard DJ 1984
Aluminium intoxication from aluminium-containing phosphate binders in children with azotemia not undergoing dialysis New England Journal of Medicine, 310(17): 1079-84
β-calcium pyrophosphate 26 232-221-5Lee JH, Chang B-S, Ryu HS and Lee C-K 2009
A 90-day subchronic toxicity study of beta-calcium pyrophosphate in rat Drug and Chemical Toxicology, 32(3): 277-282
Phosphoric acid 48 7664-38-2 American Conference of Governmental Industrial Hygienists 2001 Phosphoric acid
Documentation of the Threshold Limit Values and Biological Exposure Indices, 7th Ed
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-82
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Al(OH)3, AlPO4, Al 40 7784-30-7 Berthon G and Daydé SD 1992Why aluminium phosphate is less toxic than aluminium hydroxide
Journal of the American College of Nutrition, 11(3): 340-348
No IP substances investigated N/A N/A Vaezy A and Budson DC 1978Phalangeal metastases from bronchogenic carcinoma JAMA, 239(3): 225-226
Orthophosphoric acid 48 7664-38-2 Daydé S, Filella M and Berthon G 1990
Aluminium speciation studies in biological fluids. Part 3. Quantitative investigation of aluminium-phosphate complexes and assessment of their potential significance in vivo Journal of Inorganic Biochemistry, 38: 241-259
Orthophosphoric acid, pyrophosphoric acid, metaphosphoric acid 45, 48, 50
245-490-9, 233-782-9, 231-633-
2, 219-574-0 Graham T 1833Researches on the arsenates, phosphates and modifications of phosphoric acid
Alembic Club, London Agents Simpkin, Marshall, Hamilton, Kent & Co Ltd (1904)
monoammonium phosphate, diammonium phosphate, calcium phosphate 18, 19
233-330-0, 231-987-8 Hopmans P and Bickford R 2003
Research Report No. 70: Effects of fire retardant on soils of heathland in Victoria
Department of Sustainability and Environment, PO Box 500, East Melbourne, Victoria 3002 (ISBN 1 74106 903 3)
Phosphoric acid 48 7664-38-2 King WA 1943
Comparison of molasses-alfalfa silage and phosphoric acid-alfalfa silage as feeds for the milking cow NJ Agricultural Experiment Station Bulletin 704
Phosphoric acid 48 7664-38-2 King WA 1944
Comparison of molasses-oat silage and phosphoric acid-oat silage as feeds for the milking cow NJ Agricultural Experiment Station Bulletin 708
Ammonium phosphate, diammonium phosphate 18, 19
233-330-0, 231-987-8 Norris LA and Webb WL 1989 Effects of fire retardant on water quality USDA Forest Service Gen Tech Rep PSW-109
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-83
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Fused tricalcium phosphate, raw rock phosphate (P2O5) 23 231-840-8
Mather RE, Pratt AD and Holdaway CW 1949
Fused tricalcium phosphate as a low-fluorine phosphorus supplement for dairy cattle J Dairy Science, 32(3): 228-235
Phosphorus (unspecified), ammonium phosphate, aminomethylphosphonic acid 18 233-330-0
Norris LA, Lorz HW and Gregory SV 1983
Influence of forest rangeland management on anadromous fish habitat in western North America: Forest chemicals
USDA Forest Service General Technical Report PSW-149
Phosphates and superphosphates, phosphorus and compounds, phosphoric acid Various Various Parmeggiani L (Ed) 1983 Volume 2: L-Z
Encyclopaedia of occupational health and safety third (revised) edition (ISBN 92-2-103291-4)
No IP substances investigated N/A N/A Penner GE 1980 Acid ingestion: toxicology and treatment Ann Emerg Med, 9(7): 374-379
Phosphorus and phosphorus compounds, organophosphate insecticides Various Various Sullivan JB and Krieger GR (Eds) 1992
Hazardous materials toxicology: clinical principles of environmental health
Williams & Wilkins, 428 East Preston Street, Baltimore, Maryland 21202, USA (ISBN 0-683-08025-3)
Phosphoric acid 48 7664-38-2 Anon 1957 Hygienic guide series: phosphoric acidAmerican Industrial Hygiene Association quarterly, 18(2): 175-176
Rock phosphate N/A N/ABethke RM, Kick CH, Edgington BH and Wilder OH 1930
The effect of feeding sodium fluoride and rock phosphate on bone development in swine: a preliminary report J Anim Sci: 29-33
Phosphate (unspecified) N/A N/ARitz E, Hahn K, Ketteler M, Kuhlmann MK and Mann J 2012 Phosphate additives in food—a health risk Deutsches Ärzteblatt International, 109(4):49-55
Phosphorus, phosphoric acid, phosphorus pentoxide, phosphorus chlorides 48 7785-88-8
US Office of Health and Environmental Assessment 1990
Summary review of health effects associated with elemental inorganic phosphorus compounds EPA/600/8-89-072
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphate (IP) Consortium 16th April 2012 - page 1-84
Substance
Sub ID CAS Nr.
AuthorsStudy
YearObject [title of the article] Organism tested Source [journal name]
Phosphoric acid and various other phosphorus containing substances 48 7785-88-8 Forbes EB and Keith MH 1914
Ohio Agricultural Experiment Station Technical Series, Bulletin No 5: Phosphorus compounds in animal metabolism Wooster, Ohio, USA
Various Various Various Gilbert A and Posternak S 1903La medication phosphoree envisagee au point de vue des echanges nutritifs de l'organisme L'Oeuvre med-chir 36: 48
Phosphoric acid 48 7785-88-8 US EPA 2011 Phosphoric acid; CASRN 7664-38-2 Integrated Risk Information System (IRIS)
Triple super phosphate, rock phosphate, monocalcium phosphate, tricalcium phosphate 21, 23
7758-23-8, 65996-95-4, 7758-87-4
Ownby DR, Galvan KA and Lydy MJ 2005
Lead and zinc bioavailability to Eisenia fetida after phosphorus amendment to repository soils Environmental Poluution, 136: 315-321
dicalcium phosphate, tricalcium phosphate 22, 23
231-826-1, 7758-87-4 Poty P-L 1932
Phosphates bicalcique et tricalcique dans l'alimentation des animaux domestiques Ecole Nationale Veterinaire D'Alfort
Raw rock phosphate N/A N/A Reed OE and Huffman CF 1928
Dairy cattle need phosphorus in ration: lack of this element causes depraved appetites of animals
Michigan Agricultural Experiment Station Quarterly Bulletin, 10(4): 152-156 [ISBN 00976911]
Pyrophosphoric acid, sodium pyrophosphate 5, 50
7758-16-9, 2466-09-3 Withers WA and Ray BJ 1913
Studies in cotton seed meal intoxication I: Pyrophosphoric acid Journal of Biological Chemistry, XIV(2): 53-58
Publicly available published studies of which the IP Consortium has purchased a copyright copy
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-1
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
copper-II-hydroxyphosphate 38 12158-74-6 9.1.1 Short term acute toxicity daphnia [v 7.1.1]Bernd Aldorf, BTA 2004 Acute toxicity Daphnia
copper-II-hydroxyphosphate 38 12158-74-6 8.5.1 Acute toxicity, oral [vi 6.5.1]
Mr D. Kuhn, Dr Francois Richeux 2004 Acute oral toxicity Rat
sodium metaphosphate insoluble HO3PNa 11 10361-03-2 9.1.1 Short term acute toxicity daphnia [v 7.1.1] Dr. H. Lebertz 1999 Acute toxicity Daphnia
diammonium phosphate 19 7783-28-0 9.1.1 Short term acute toxicity daphnia [v 7.1.1] Dr. H. Lebertz 1999 Acute toxicity Daphnia
copper (II)-pyrophosphate 37 10102-90-6 9.1.1 Short term acute toxicity daphnia [v 7.1.1]Bernd Aldorf, BTA 2004 Acute toxicity Daphnia
copper (II)-pyrophosphate 37 10102-90-6 8.5.1 Acute toxicity, oral [vi 6.5.1]
Mr D. Kuhn, Dr Francois Richeux 2004 Acute oral toxicity Rat
boron phosphate 46 13308-51-5 9.1.1 Short term acute toxicity daphnia [v 7.1.1] Dr. H. Lebertz 1999 Acute toxicity Daphnia
ammonium polyphosphate 20 14728-39-3 9.1.1 Short term acute toxicity daphnia [v 7.1.1] Dr. H. Lebertz 1999 Acute toxicity Daphnia
STPP 0 7758-29-4 8.2.1 In vivo eye irritation [vi 6.2.1]Becker J., Parke G. St. E. 1975 Effects on eye mucosa - albinos rabbits
STPP 0 7758-29-4 8.1.1 In vivo skin irritation [vi 6.1.1]Becker J., Parke G. St. E 1975 Skin irritation - albinos rabbits
STPP 0 7758-29-4 9.1.1 Short term acute toxicity daphnia [v 7.1.1]
Vaishnav D.D., Yurk J.J., Ives, Wade B.A. 1990 Acute toxicity - Daphnia
STPP 0 7758-29-4 8.2.1 In vivo eye irritation [vi 6.2.1]W. Barta, T. Cascieri, 1986 Preliminary eye irritation - rabbits
STPP 0 7758-29-4 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1989 Skin irritation - rabbits
STPP 0 7758-29-4 8.5.1 Acute toxicity, oral [vi 6.5.1] Watt B 1997 Acute oral toxicity - Rats
STPP 0 7758-29-4 8.5.2 Acute toxicity, inhalation [vi 6.5.2]
Jackson G.C., Hardy C.J., Chanter D.O. 1989 Acute inhalation toxicity - Rats
Tetrapotassium pyrophosphate 15 7320-34-5 9.1.1 Short term acute toxicity daphnia [v 7.1.1]
Vaishnav D.D., Yurk J.J., Ives, Wade B.A. 1991 Acute toxicity Daphnia
Sodium hexametaphosphate 10 10124-56-8 9.1.1 Short term acute toxicity daphnia [v 7.1.1] Yurk J.J. 1993 Acute toxicity Daphnia
Dipotassium phosphate 13 7758-11-4 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1987 Skin irritation and toxicity rabbits
Dipotassium phosphate 13 7758-11-4 8.5.3 Acute toxicity, dermal [vi 6.5.3] Freeman C 1987 Skin irritation and toxicity rabbits
Tri-potassium phosphate 14 7778-53-2 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1987 Skin irritation and toxicity rabbits
Tri-potassium phosphate 14 7778-53-2 8.5.3 Acute toxicity, dermal [vi 6.5.3] Freeman C 1987 Skin irritation and toxicity rabbits
Mono-sodium phosphate 2 7558-80-7 8.2.1 In vivo eye irritation [vi 6.2.1] Freeman C 1987 Eye irritation rabbits
Sodium hexametaphosphate 10 10124-56-8 8.2.1 In vivo eye irritation [vi 6.2.1] Freeman C 1986 Eye irritation rabbits
Mono-potassium phosphate 12 7778-77-0 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1990 Skin irritation rabbits
Mono-potassium phosphate 12 7778-77-0 8.2.1 In vivo eye irritation [vi 6.2.1] Freeman C 1986 Eye irritation rabbits
Potassium tri-polyphosphate 16 13845-36-8 8.2.1 In vivo eye irritation [vi 6.2.1] Freeman C 1987 Eye irritation rabbits
Dipotassium phosphate 13 7758-11-4 8.2.1 In vivo eye irritation [vi 6.2.1] Freeman C 1987 Eye irritation rabbits
Tetrapotassium pyrophosphate 15 7320-34-5 8.2.1 In vivo eye irritation [vi 6.2.1] Freeman C 1987 Eye irritation rabbits
Di-sodium phosphate 3 7558-79-4 8.2.1 In vivo eye irritation [vi 6.2.1] Freeman C 1987 Eye irritation rabbits
Di-potassium phosphate 13 7758-11-4 8.5.1 Acute toxicity, oral [vi 6.5.1] Freeman C 1987 Preliminary oral toxicity - Rats
Di-potassium phosphate 13 7758-11-4 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1987 Skin irritation and toxicity rabbits
Di-potassium phosphate 13 7758-11-4 8.5.3 Acute toxicity, dermal [vi 6.5.3] Freeman C 1987 Skin irritation and toxicity rabbits
Tetra-potassium pyrophosphate 15 7320-34-5 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1988 Skin irritation rabbits
Tetra-potassium pyrophosphate 15 7320-34-5 8.5.3 Acute toxicity, dermal [vi 6.5.3] Freeman C 1988 Skin toxicity rabbits
Tetra-sodium pyrophosphate 7 7722-88-5 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1988 Skin irritation rabbits
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IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-2
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
Phosphoric acid 48 7664-38-2 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1989 Skin irritation rabbits
Mono-sodium phosphate 2 7558-80-7 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1990 Skin irritation rabbits
Potassium tri-polyphosphate 16 13845-36-8 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1990 Skin irritation rabbits
Sodium hexametaphosphate 10 10124-56-8 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1990 Skin irritation rabbits
Tricalcium phosphate 24 1306-06-5 8.1.1 In vivo skin irritation [vi 6.1.1] Freeman C 1993 Skin irritation rabbits
Mono-sodium phosphate 2 7558-80-7 8.5.2 Acute toxicity, inhalation [vi 6.5.2] Signorin J. 1993 Acute inhalation toxicity rats
Sodium Acid Pyrophosphate 5 7758-16-9 8.5.2 Acute toxicity, inhalation [vi 6.5.2] Signorin J. 1993 Acute inhalation toxicity rats
Sodium hexametaphosphate 10 10124-56-8 8.5.2 Acute toxicity, inhalation [vi 6.5.2] Signorin J. 1993 Acute inhalation toxicity rats
Tetrapotassium pyrophosphate 15 7320-34-5 8.5.2 Acute toxicity, inhalation [vi 6.5.2] Signorin J. 1993 Acute inhalation toxicity rats
STPP 0 7758-29-4 8.1.1 In vivo skin irritation [vi 6.1.1] Dr. Weigand M. 1966
“Natriumtripolyphosphat toxikologische prüfung” - Skin and eye irritation - rats - Translation 2002 by Roth T., Clariant.
STPP 0 7758-29-4 8.2.1 In vivo eye irritation [vi 6.2.1] Dr. Weigand M. 1966
“Natriumtripolyphosphat toxikologische prüfung” - Skin and eye irritation - rats - Translation 2002 by Roth T., Clariant.
STPP 0 7758-29-4 Growth inhibition of algae [v 7.1.2 ]Herschke B., Cellier 1985
"Ecotoxicilogie du tripolyphosphate …" - Toxicity algae (fresh and sea water)
STPP 0 7758-29-4 9.1.1 Short term acute toxicity daphnia [v 7.1.1] Dion M 1985"Etude de la toxicité aquatique …" - Acute toxicity daphnia and zebra fish
STPP 0 7758-29-4 9.1.3 Short term acute toxicity fish [v 7.1.3] Dion M 1985"Etude de la toxicité aquatique …" - Acute toxicity daphnia and zebra fish
STPP 0 7758-29-4 8.1.1 In vivo skin irritation [vi 6.1.1]Kamienski F. X., C.H. Bullock 1971
Acute oral (rat) and dermal toxicity, skin and eye irritation (all rabbit)
STPP 0 7758-29-4 8.5.1 Acute toxicity, oral [vi 6.5.1]Kamienski F. X., C.H. Bullock 1971
Acute oral (rat) and dermal toxicity, skin and eye irritation (all rabbit)
STPP 0 7758-29-4 8.5.3 Acute toxicity, dermal route [vi 6.5.3]Kamienski F. X., C.H. Bullock 1971
Acute oral (rat) and dermal toxicity, skin and eye irritation (all rabbit)
sodium aluminum phosphate 43 7785-88-8 8.6.2 subchronic toxicity, oral [vi 6.5.1] Smith P.S. 1972 90 days subacute oral toxicity
sodium aluminum phosphate 43 7785-88-8 8.6.2 subchronic toxicity, oral [vi 6.5.1] Reyna M.S. 1973 90 days subacute oral toxicity
sodium aluminum phosphate 43 7785-88-8 8.6.1 Short-term repeated dose toxicity, oral Smith P.S. 1972 30 days pilot study
sodium aluminum phosphate 43 7785-88-8 8.6.2 90-day repeated-dose toxicity Mastalski K. 1972 90 days subacute oral toxicity
sodium Acid Pyrophosphate 5 7758-16-9 8.4 in vivo Mutagenicity
Newell G.W, Jorgenson T.A. Simon V.F. 1974 Host-mediated assay
sodium Acid Pyrophosphate 5 7758-16-9 8.4 In vitro Mutagenicity
Newell G.W, Jorgenson T.A. Simon V.F. 1974 in vitro microbial assay
sodium Acid Pyrophosphate 5 7758-16-9 8.4 in vivo Mutagenicity
Newell G.W, Jorgenson T.A. Simon V.F. 1974 dominant lethal test
sodium Acid Pyrophosphate 5 7758-16-9 8.4 in vivo Mutagenicity
Newell G.W, Jorgenson T.A. Simon V.F. 1974 mouse translocation test
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-3
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
sodium acid Pyrophosphate 5 7758-16-9 8.5.1 Acute toxicity, oral
Newell G.W, Jorgenson T.A. Simon V.F. 1974
Mutagenicity evaluation - precurser to RDL and mouse translocation
sodium Acid Pyrophosphate 5 7758-16-9 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
sodium Acid Pyrophosphate 5 7758-16-9 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
sodium Acid Pyrophosphate 5 7758-16-9 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
sodium Acid Pyrophosphate 5 7758-16-9 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
deicer ID1352D mix NA 8.5.1 Acute toxicity, oral [vi 6.5.1] Younger F.M. 1965 single oral dose
deicer ID1352D mix NA 8.5.3 Acute toxicity, dermal Younger F.M. 1965acute skin absorption minimal lethal dose
deicer ID1352D mix NA 8.1.1 In vivo skin irritation [vi 6.1.1] Younger F.M. 1965 Skin irritation - albinos rabbits
deicer ID1352D mix NA 8.2.1 In vivo eye irritation [vi 6.2.1] Younger F.M. 1965 Eye irritation rabbits
PhosCheck202 (diammonium phosphates mix) 19 7783-28-0 8.5.1 Acute toxicity, oral [vi 6.5.1] Younger F.M. 1965 single oral dose
PhosCheck202 (diammonium phosphates mix) 19 7783-28-0 8.5.3 Acute toxicity, dermal Younger F.M. 1965
acute skin absorption minimal lethal dose
PhosCheck202 (diammonium phosphates mix) 19 7783-28-0 8.1.1 In vivo skin irritation [vi 6.1.1] Younger F.M. 1965 Skin irritation - albinos rabbits
PhosCheck202 (diammonium phosphates mix) 19 7783-28-0 8.2.1 In vivo eye irritation [vi 6.2.1] Younger F.M. 1965 Eye irritation rabbits
diammonium phosphate 19 7783-28-0 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
diammonium phosphate 19 7783-28-0 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
diammonium phosphate 19 7783-28-0 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
diammonium phosphate 19 7783-28-0 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
monoammonium phosphate 18 7722-76-1 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
monoammonium phosphate 18 7722-76-1 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
monoammonium phosphate 18 7722-76-1 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
monoammonium phosphate 18 7722-76-1 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
trisodium phosphate 4 7601-54-9 8.1.1 In vivo skin irritation [vi 6.1.1] Younger F.M. 1962 Skin irritation - albinos rabbits
trisodium phosphate 4 7601-54-9 8.2.1 In vivo eye irritation [vi 6.2.1] Younger F.M. 1962 Eye irritation rabbits
trisodium phosphate 4 7601-54-9 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
trisodium phosphate 4 7601-54-9 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
trisodium phosphate 4 7601-54-9 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
trisodium phosphate 4 7601-54-9 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
trisodium phosphate 4 7601-54-9 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1977 single oral dose
trisodium phosphate 4 7601-54-9 8.5.3 Acute toxicity, dermal Birch M.D. 1977acute skin absorption minimal lethal dose
trisodium phosphate 4 7601-54-9 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1977 Skin irritation - albinos rabbits
trisodium phosphate 4 7601-54-9 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1977 Eye irritation rabbits
disodium phosphate 3 7558-79-4 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1972 skin irritation
disodium phosphate 3 7558-79-4 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
disodium phosphate 3 7558-79-4 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
disodium phosphate 3 7558-79-4 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
disodium phosphate 3 7558-79-4 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
monosodium phosphate 2 7558-80-7 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
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IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-4
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
monosodium phosphate 2 7558-80-7 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
monosodium phosphate 2 7558-80-7 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
monosodium phosphate 2 7558-80-7 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
sodium trimetaphosphate 8 7785-84-4 8.5.1 Acute toxicity, oral [vi 6.5.1] Younger F.M. 1961 single oral dose
sodium trimetaphosphate 8 7785-84-4 8.1.1 In vivo skin irritation [vi 6.1.1] Younger F.M. 1961 Skin irritation - albinos rabbits
sodium trimetaphosphate 8 7785-84-4 8.2.1 In vivo eye irritation [vi 6.2.1] Younger F.M. 1961 Eye irritation rabbits
insoluble sodium metaphosphate 11 10361-03-2 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
insoluble sodium metaphosphate 11 10361-03-2 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
insoluble sodium metaphosphate 11 10361-03-2 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
insoluble sodium metaphosphate 11 10361-03-2 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
tetrasodium pyrophosphate 7 7722-88-5 8.1.1 In vivo skin irritation [vi 6.1.1] Younger F.M. 1962 Skin irritation - albinos rabbits
tetrasodium pyrophosphate 7 7722-88-5 8.2.1 In vivo eye irritation [vi 6.2.1] Younger F.M. 1962 Eye irritation rabbits
tetrasodium pyrophosphate 7 7722-88-5 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
tetrasodium pyrophosphate 7 7722-88-5 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
tetrasodium pyrophosphate 7 7722-88-5 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
tetrasodium pyrophosphate 7 7722-88-5 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
monopotassium phosphate 12 7778-77-0 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
monopotassium phosphate 12 7778-77-0 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
monopotassium phosphate 12 7778-77-0 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
monopotassium phosphate 12 7778-77-0 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
dipotassium phosphate 13 7758-11-4 8.2.1 In vivo eye irritation [vi 6.2.1] Blaszcak D.L. 1986 Eye irritation rabbits
dipotassium phosphate 13 7758-11-4 Acute oral toxicity Blaszcak D.L. 1986 Acute oral toxicity
dipotassium phosphate 13 7758-11-4 Acute dermal toxicity Blaszcak D.L. 1986 Acute dermal toxicity
Tripotassium phosphate 14 7778-53-2 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1976 single oral dose
Tripotassium phosphate 14 7778-53-2 8.5.3 Acute toxicity, dermal Birch M.D. 1976acute skin absorption minimal lethal dose
Tripotassium phosphate 14 7778-53-2 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1976 Skin irritation - albinos rabbits
Tripotassium phosphate 14 7778-53-2 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1976 Eye irritation rabbits
tetrapotassium phosphate 15 7320-34-5 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
tetrapotassium phosphate 15 7320-34-5 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
tetrapotassium phosphate 15 7320-34-5 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
tetrapotassium phosphate 15 7320-34-5 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
tetra-potassium pyrophosphate 15 7320-34-5 8.5.1 Acute toxicity, oral [vi 6.5.1] Younger F.M. 1961 single oral dose
tetra-potassium pyrophosphate 15 7320-34-5 8.1.1 In vivo skin irritation [vi 6.1.1] Younger F.M. 1961 Skin irritation - albinos rabbits
tetra-potassium pyrophosphate 15 7320-34-5 8.2.1 In vivo eye irritation [vi 6.2.1] Younger F.M. 1961 Eye irritation rabbits
monocalcium Phosphate 21 7758-23-8 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
monocalcium Phosphate 21 7758-23-8 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
monocalcium Phosphate 21 7758-23-8 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
monocalcium Phosphate 21 7758-23-8 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
dicalcium phosphate 22 7757-93-9 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1974 single oral dose
dicalcium phosphate 22 7757-93-9 8.5.3 Acute toxicity, dermal Birch M.D. 1974acute skin absorption minimal lethal dose
dicalcium phosphate 22 7757-93-9 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1974 Skin irritation - albinos rabbits
dicalcium phosphate 22 7757-93-9 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1974 Eye irritation rabbits
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IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-5
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
dicalcium phosphate 22 7757-93-9 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
dicalcium phosphate 22 7757-93-9 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
dicalcium phosphate 22 7757-93-9 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
dicalcium phosphate 22 7757-93-9 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
calcium pyrophosphate 26 7790-76-3 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1973 single oral dose
calcium pyrophosphate 26 7790-76-3 8.5.3 Acute toxicity, dermal Birch M.D. 1973acute skin absorption minimal lethal dose
calcium pyrophosphate 26 7790-76-3 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1973 Skin irritation - albinos rabbits
calcium pyrophosphate 26 7790-76-3 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1973 Eye irritation rabbits
trimagnesium phosphate 30 7757-87-1 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1975 single oral dose
trimagnesium phosphate 30 7757-87-1 8.5.3 Acute toxicity, dermal Birch M.D. 1975acute skin absorption minimal lethal dose
trimagnesium phosphate 30 7757-87-1 8.1.1 In vivo skin irritation [vi 6.1.1] Birch M.D. 1975 Skin irritation - albinos rabbits
trimagnesium phosphate 30 7757-87-1 8.2.1 In vivo eye irritation [vi 6.2.1] Birch M.D. 1975 Eye irritation rabbits
STPP 0 7758-29-4 8.1.1 In vivo skin irritation [vi 6.1.1] Younger F.M. 1962 Skin irritation - albinos rabbits
STPP 0 7758-29-4 8.2.1 In vivo eye irritation [vi 6.2.1] Younger F.M. 1962 Eye irritation rabbits
STPP 0 7758-29-4 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1976 acute oral toxicity – Rats
STPP 0 7758-29-4 8.5.1 Acute toxicity, oral [vi 6.5.1] Birch M.D. 1976 acute oral toxicity – Rats
Monosodium orthophosphate 2 7558-80-7 hydrolysis Gaillot J.C. 1985etude des especes phosphatees en sortie de machine a laver
Sodium pyrophosphate 5 7758-46-9 hydrolysis Gaillot J.C. 1985etude des especes phosphatees en sortie de machine a laver
Sodium tripolyphosphate hexaydrate 0 7758-29-4 hydrolysis Gaillot J.C. 1985etude des especes phosphatees en sortie de machine a laver
orthophosphate NA 8.6.1 Short term repeated doses Hodge C.H. 1956 pilot toxicity test
sodium metaphosphate 10 10124-56-8 8.6.1 Short term repeated doses Hodge C.H. 1956 pilot toxicity test
sodium tripolyphosphate 0 7758-29-4 8.6.1 Short term repeated doses Hodge C.H. 1956 pilot toxicity test
sodium trimetaphosphate 8 7785-84-4 8.6.1 Short term repeated doses Hodge C.H. 1956 pilot toxicity test
sodium tetrametaphosphate NA 20758-95-6 8.6.1 Short term repeated doses Hodge C.H. 1956 pilot toxicity test
orthophosphate NA 0 8.6.1 Short term repeated doses Hodge C.H. 1956 pilot toxicity test
sodium metaphosphate 10 10124-56-8 8.6.1 Short term repeated doses Hodge C.H. 1956 pilot toxicity test
sodium tripolyphosphate 0 7758-29-4 8.6.1 Short term repeated doses Hodge C.H. 1956 pilot toxicity test
sodium trimetaphosphate 8 7785-84-4 8.6.1 Short term repeated doses Hodge C.H. 1956 pilot toxicity test
sodium tetrametaphosphate NA 20758-95-6 8.6.1 Short term repeated doses Hodge C.H. 1956 pilot toxicity test
sodium tripolyphosphate 0 7758-29-4 8.6.3 Long term oral tox Hodge C.H. 1959 chronic oral toxicity studies in rats
sodium trimetaphosphate 8 7785-84-4 8.6.3 Long term oral tox Hodge C.H. 1960 chronic oral toxicity studies in rats
sodium trimetaphosphate 8 7785-84-4 Acute tox - other (IP route) Hodge C.H. 1960 chronic oral toxicity studies in rats
sodium hexametaphosphate 10 10124-56-8 8.6.3 Long term oral tox Hodge C.H. 1960 chronic oral toxicity studies in rats
sodium hexametaphosphate 10 10124-56-8 8.5.1. Acute toxicity oral Hodge C.H. 1960 Acute oral toxicity
sodium tripolyphosphate 0 7758-29-4 8.7.3 Reproductive toxicity multigeneration Hodge C.H. 1959 chronic oral toxicity studies in rats
sodium hexametaphosphate 10 10124-56-8 8.7.3 Reproductive toxicity multigeneration Hodge C.H. 1960 chronic oral toxicity studies in rats
sodium trimetaphosphate 8 7785-84-4 8.7.3 Reproductive toxicity multigeneration Hodge C.H. 1960 chronic oral toxicity studies in rats
sodium tripolyphosphate 0 7758-29-4 8.9.1 Carcinogenicity Hodge C.H. 1959 chronic oral toxicity studies in rats
sodium hexametaphosphate 10 10124-56-8 8.9.1 Carcinogenicity Hodge C.H. 1960 chronic oral toxicity studies in rats
sodium trimetaphosphate 8 7785-84-4 8.9.1 Carcinogenicity Hodge C.H. 1960 chronic oral toxicity studies in rats
phosphates NA Eutrophication De Madariaga 2007 Europhication risk assessment
sodium tripolyphosphate 0 7758-29-4 9.1.1 Short term acute toxicity daphnia [v 7.1.1] Pandard 2004Inhibition of the mobility of Daphnia magna
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IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-6
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
sodium tripolyphosphate 0 7758-29-4 9.1.1 Short term acute toxicity daphnia [v 7.1.1] Pandard 2004Inhibition of the mobility of Ceriodaphnia dubia
sodium tripolyphosphate 0 7758-29-48.3.2. Skin sensitisation in vivo test (LLNA first choice method) Bradshaw J. 2008 local lymph node assay
sodium tripolyphosphate 0 7758-29-4 7.4. relative densityWoolley A.j., Woolley S.M. 2008 determination of relative density
sodium tripolyphosphate 0 7758-29-4 8.3.2 Skin Sensitisation (Buehler method) P&G 1999 Buehler study
dicalcium phosphate 22 7757-93-9 8.5.1 acute toxicity, oral Kamienski FX 1970 toxicity studies on dicalcium phosphate
dicalcium phosphate 22 7757-93-9 8.5.1 subacute toxicity(14 day), oral Kamienski FX 1970 toxicity studies on dicalcium phosphate
sodium aluminum phosphate 43 7785-88-8 8.6.2 subchronic toxicity, oral
Pettersen JC, Zwicker GM and Hackett DS 1987
26-week subchronic toxicity study with kasal in dogs
trisodium phosphate (dodecahydrate) 4 7601-54-9 8.5.1 Acute toxicity, oral Pontrepka RF 1981trisodium phosphate, crystalline. Toxicity
trisodium phosphate (dodecahydrate) 4 7601-54-9 8.5.3 Acute toxicity, dermal Pontrepka RF 1981trisodium phosphate, crystalline. Toxicity
trisodium phosphate (dodecahydrate) 4 7601-54-9 8.1.1 skin irritation in vivo Pontrepka RF 1981trisodium phosphate, crystalline. Toxicity
trisodium phosphate (dodecahydrate) 4 7601-54-9 8.2.1 eye irritation in vivo Pontrepka RF 1981trisodium phosphate, crystalline. Toxicity
trisodium phosphate (dodecahydrate) 4 7601-54-9 9.1.3 short-term toxicity testing on fish Potrepka RF 1981trisodium phosphate, crystalline. Toxicity
by-product of phosphoric acid' n/aunknown
8.5.1 Acute toxicity, oral ? 1968 ?
sodium aluminum phosphate 437785-88-8
8.5.1 Acute toxicity, oral Bullock CH 1970Acute oral toxicity of levn-lite in male rats
Phosphoric acid 487664-38-2
8.2.1 eye irritation in vivoBullock CH and Kamienski FX. 1971 Toxicology lab report
Phosphoric acid 487664-38-3
8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1971 Toxicology lab report
Phosphoric acid 48 7664-38-2 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1971 Toxicology lab report
Super phosphoric acid N/A ? 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1972 Toxicology lab report
diammonium phosphate 19 7783-28-0 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1972 Toxicology lab report
diammonium phosphate 19 7783-28-0 8.5.1 Acute toxicity, oral Bullock CH and Kamienski FX. 1972 Toxicology lab report
monoaluminium phosphate 39 13530-50-2 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1972 Toxicology lab report
monoaluminium phosphate 39 13530-50-2 8.5.1 Acute toxicity, oral Bullock CH and Kamienski FX. 1972 Toxicology lab report
monoammonium phosphate 18 7722-76-1 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1972 Toxicology lab report
monocalcium phosphate 21 7758-23-8 8.5.1 Acute toxicity, oral Bullock CH and Kamienski FX. 1972 Toxicology lab report
monocalcium phosphate 21 7758-23-8 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1972 Toxicology lab report
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-7
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
monomagnesium phosphate (solution) 31 13092-66-5 8.5.1 Acute toxicity, oral Bullock CH and Kamienski FX. 1972 Toxicology lab report
monomagnesium phosphate (solution) 31 13092-66-5 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1972 Toxicology lab report
monopotassium phosphate 12 7778-77-0 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1972 Toxicology lab report
Potassium tri-polyphosphate 16 13845-36-8 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1972 Toxicology lab report
sodium aluminum phosphate 43 7785-88-8 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1972 Toxicology lab report
Tetrapotassium pyrophosphate 15 7320-34-5 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1972 Toxicology lab report
tetrasodium pyrophosphate 7 7722-88-5 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX. 1972 Toxicology lab report
tetrasodium pyrophosphate 7 7722-88-5 8.5.1 Acute toxicity, oral Bullock CH and Kamienski FX. 1972 Toxicology lab report
dipotassium phosphate 13 7785-11-4 8.5.1 Acute toxicity, oral Bullock CH and Kamienski FX. 1972 Toxicology lab report
iron orthophosphate 27 10045-86-0 8.5.1 Acute toxicity, oral Bullock CH and Kamienski FX. 1972 Toxicology lab report
monosodium phosphate 2 7558-80-7 8.5.1 Acute toxicity, oral Bullock CH and Kamienski FX. 1972 Toxicology lab report
sodium Acid Pyrophosphate 5 7758-16-9 8.5.1 Acute toxicity, oral Bullock CH and Kamienski FX. 1972 Toxicology lab report
sodium hexametaphosphate 9 68915-31-1 8.5.1 Acute toxicity, oral Bullock CH and Kamienski FX. 1972 Toxicology lab report
Tricalcium phosphate 24 7758-87-4 8.5.1 Acute toxicity, oral Bullock CH and Kamienski FX. 1972 Toxicology lab report
polyphosphoric acid 49 8017-16-1 8.1.1 skin irritation in vivo Bullock CH and
Heil JF 1973 Toxicology lab report
trisodium phosphate - dodecahydrate 4 7601-54-9 8.1.1 skin irritation in vivo Henderson L and
Joiner RL 1974 Toxicology lab report
trisodium phosphate 4 7601-54-9 8.1.1 skin irritation in vivo Henderson L and
Joiner RL 1974 Toxicology lab report
aluminum metaphosphate 42 13776-88-0 8.1.1 skin irritation in vivo Joiner RL 1975 Toxicology lab report
aluminum metaphosphate 42 13776-88-0 8.5.1 Acute toxicity, oral Joiner RL 1975 Toxicology lab report
monoaluminium phosphate 39 13530-50-2 8.5.1 Acute oral toxicity Joiner RL 1975 Toxicology lab report
monoaluminium phosphate 39 13530-50-2 8.1.1 skin irritation in vivo Joiner RL 1975 Toxicology lab report
monomagnesium phosphate (solution) 31 13092-66-5 8.5.1 Acute oral toxicity Joiner RL 1975 Toxicology lab report
monomagnesium phosphate (solution) 31 13092-66-5 8.1.1 skin irritation in vivo Joiner RL 1975 Toxicology lab report
tetrasodium pyrophosphate 7 7722-88-5 8.5.1 Acute toxicity, oral Jones B 1979 Toxicology lab report
tetrasodium pyrophosphate 7 7722-88-5 8.5.3 Acute toxicity, dermal Jones B 1979 Toxicology lab report
tetrasodium pyrophosphate 7 7722-88-5 8.1.1 skin irritation in vivo Jones B 1979 Toxicology lab report
tetrasodium pyrophosphate 7 7722-88-5 8.2.1 eye irritation in vivo Jones B 1979 Toxicology lab report
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-8
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
sodium aluminum phosphate 43 7785-88-8 8.6.2 Sub-chronic toxicity, 6 months Katz AC 1981A 6-moth sub-chronic dietary study with LEVAIR in Beagle dogs
sodium aluminum phosphate (KASAL) 43 7785-88-8 8.5.1 Acute toxicity, oral Jones BJ 1980 Toxicology lab report
sodium aluminum phosphate (KASAL) 43 7785-88-8 8.5.3 Acute toxicity, dermal Jones BJ 1980 Toxicology lab report
sodium aluminum phosphate (KASAL) 43 7785-88-8 8.1.1 skin irritation in vivo Jones BJ 1980 Toxicology lab report
sodium aluminum phosphate (KASAL) 43 7785-88-8 8.2.1 eye irritation in vivo Jones BJ 1980 Toxicology lab report
Tricalcium phosphate 24 1306-06-5 8.5.1 Acute toxicity, oral Foster TL 1985 Toxicology lab report
Tricalcium phosphate 24 1306-06-5 8.5.3 Acute toxicity, dermal Foster TL 1985 Toxicology lab report
Tricalcium phosphate 24 1306-06-5 8.1.1 skin irritation in vivo Foster TL 1985 Toxicology lab report
Tricalcium phosphate 24 1306-06-5 8.2.1 eye irritation in vivo Foster TL 1985 Toxicology lab report
sodium aluminum phosphate 43 7785-88-8 8.6.1 short-term repeated dose, oral, 28-day Sprague GL 19864-week dietary comparative toxicity study with KASAL in rats
trisodium phosphate (dodecahydrate) 4 7601-54-9 8.1.1 skin irritation in vivo Glaza SM 1992
Primary dermal irritation study of trisodium phosphate dodecahydrate (saturated solution at 10°C) in rabbits
trisodium phosphate (dodecahydrate) 4 7601-54-9 8.1.1 skin irritation in vivo Glaza SM 1992
Primary dermal irritation study of trisodium phosphate dodecahydrate (saturated solution at 22°C) in rabbits
trisodium phosphate (dodecahydrate) 4 7601-54-9 8.2.1 eye irritation in vivo Glaza SM 1992
Primary eye irritation study of trisodium phosphate dodecahydrate (saturated solution at 10°C) in rabbits
Phosphoric acid 48 7664-38-2 8.5.1 Acute toxicity, oral ? 1975Acute oral toxicity in rats. Compound: MCTR-1-75
Phosphoric acid 48 7664-38-2 8.5.1 Acute toxicity, oral ? 1975Acute oral toxicity in rats. Compound: MCTR-1-75
Phosphoric acid 48 7664-38-2 8.5.3 Acute toxicity, dermal Becker J and Parke G 1975
the acute dermal toxicity study of MCTR-1-75. New Zealand Albino rabbits
Phosphoric acid 48 7664-38-2 8.2.1 eye irritation, in vivo Becker J and Parke G 1975
The effects of MCTR-1-75 on the eye mucosa of new zealand abino rabbits
Phosphoric acid 48 7664-38-2 8.1.1 skin irritation in vivo Becker J and Parke G 1975
A primary dermal irritation study of MCTR-1-75 on abraded and nonabraded skin of New Zealand albino rabbits
monaluminium phosphate 39 13530-50-2 8.5.1 Acute toxicity, oral Terrell Y and Parke G 1975
Acute oral toxicity in rats. Compound: MCTR-2-75
Tripotassium phosphate 14 7778-53-2 8.5.1 Acute toxicity, oral Terrell Y and Parke G 1975
Acute oral toxicity in rats. Compound: MCTR-7-75
Tripotassium phosphate 14 7778-53-2 8.5.1 Acute toxicity, oral Terrell Y and Parke G 1975
Acute oral toxicity in rats. Compound: MCTR-7-75
Tripotassium phosphate (liquid) 14 7778-53-2 8.4.1 In vitro mutagenicicty in bacteria Jagannath DR 1977 Mutagenicity evaluation of MCTR-258
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-9
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
tetrapotassium pyrophosphate (liquid) 15 7320-34-5 8.5.3 Acute toxicity, dermalImlay P and Parke G 1977
Report on the acute dermal toxicity of rabbits
magnesium phosphate (liquid) 31 10392-66-5 8.1.1 skin irritation in vivo Nitka S 1979 DOT skin corrosion in rabbits
Magnesium phosphate (solution) 31 10392-66-5 8.5.1 Acute toxicity, oral ? 1981The acute oral toxicity of magnesium phosphate solution in albino rats
Magnesium phosphate (solution) 31 10392-66-5 8.5.3 Acute toxicity, dermal ? 1981The acute dermal toxicity of magnesium phosphate solution in albino rabbits
Magnesium phosphate (solution) 31 10392-66-5 8.2.1 eye irritation in vivo ? 1981Primary eye irritation of magnesium phosphate solution in albino rabbits
Magnesium phosphate (solution) 31 10392-66-5 8.1.1 Skin irritation in vivo ? 1981
Skin irritation of magnesium phosphate solution after a single application to albino rabbits
tetrapotassium pyrophosphate 15 7320-34-5 8.5.1 Acute toxicity, oralTerrel Y and Parke G 1975
Acute oral toxicity in rats. Compound: MCTR-6-75
tetrapotassium pyrophosphate 15 7320-34-5 8.5.1 Acute toxicity, oralTerrel Y and Parke G 1975
Acute oral toxicity in rats. Compound: MCTR-6-75
tetrapotassium pyrophosphate (liquid) 15 7320-34-5 8.4.1 Mutagenicity in bacteria Brusick DJ 1977 Mutagenicity evaluation of MCTR-257
Tripotassium phosphate (liquid) 14 7778-53-2 8.5.3 Acute toxicity, dermalImlay P and Parke G 1977
Report on the acute dermal toxicity of rabbits
dipotassium phosphate 13 7758--11-4 8.5.1 Acute toxicity, oralTerrel Y and Parke G 1975
Acute oral toxicity in rats. Compound: TDR-41-75
dipotassium phosphate 13 7758--11-4 8.5.1 Acute toxicity, oralTerrel Y and Parke G 1975
Acute oral toxicity in rats. Compound: MCTR-4-75
dipotassium phosphate 13 7758--11-4 8.5.3 Acute toxicity, dermalImlay P and Parke G 1977
Report on the acute dermal toxicity of rabbits
dipotassium phosphate 13 7758--11-4 8.4.1 Mutagenicity in bacteria Jagannath DR 1977 Mutagenicity evaluation of MCTR-256
monocalcium phosphate 21 7758-23-8 8.5.1 Acute toxicity, oral Sorenson S 1985Acute toxicity test battery for monocalcium phosphate anhydrous
monocalcium phosphate 21 7758-23-8 8.5.3 Acute toxicity, dermal Sorenson S 1985Acute toxicity test battery for monocalcium phosphate anhydrous
monocalcium phosphate 21 7758-23-8 8.1.1 Skin irritation in vivo Sorenson S 1985Acute toxicity test battery for monocalcium phosphate anhydrous
monocalcium phosphate 21 7758-23-8 8.2.1 eye irritation in vivo Sorenson S 1985Acute toxicity test battery for monocalcium phosphate anhydrous
sodium hypophosphite N/A N/A N/A Heil J 1974 N/A
monoaluminium phosphate (50% solution) 39 13530-50-2 8.1.1 Skin irritation in vivo Kamienski FX 1971 Toxicology lab report
monoaluminium phosphate (50% solution) 39 13530-50-2 8.2.1 eye irritation in vivo Kamienski FX 1971 Toxicology lab report
monoaluminium phosphate (50% solution) 39 13530-50-2 8.2.1 Acute toxicity, oral Kamienski FX 1971 Toxicology lab report
monoaluminium phosphate (50% solution) 39 13530-50-2 8.5.3 Acute toxicity, dermal Kamienski FX 1971 Toxicology lab report
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-10
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
tripotassium phosphate 14 7778-53-2 8.5.1 Acute toxicity, oral Kamienski FX 1971 Toxicology lab report
tripotassium phosphate 14 7778-53-2 8.5.3 Acute toxicity, dermal Kamienski FX 1971 Toxicology lab report
tripotassium phosphate 14 7778-53-2 8.1.1 Skin irritation in vivo Kamienski FX 1971 Toxicology lab report
tripotassium phosphate 14 7778-53-2 8.2.1 eye irritation in vivo Kamienski FX 1971 Toxicology lab report
aluminium metaphosphate 42 13776-88-0 8.5.1 Acute toxicity, oral Kamienski FX 1971 Toxicology lab report
aluminium metaphosphate 42 13776-88-0 8.5.3 Acute toxicity, dermal Kamienski FX 1971 Toxicology lab report
aluminium metaphosphate 42 13776-88-0 8.1.1 Skin irritation in vivo Kamienski FX 1971 Toxicology lab report
aluminium metaphosphate 42 13776-88-0 8.2.1 eye irritation in vivo Kamienski FX 1971 Toxicology lab report
sodium iron pyrophosphate N/A 10045-87-1 8.5.1 Acute toxicity, oral Kamienski FX 1971 Toxicology lab report
sodium iron pyrophosphate N/A 10045-87-1 8.5.3 Acute toxicity, dermal Kamienski FX 1971 Toxicology lab report
sodium iron pyrophosphate N/A 10045-87-1 8.1.1 Skin irritation in vivo Kamienski FX 1971 Toxicology lab report
sodium iron pyrophosphate N/A 10045-87-1 8.2.1 eye irritation in vivo Kamienski FX 1971 Toxicology lab report
sodium trimetaphosphate 8 7785-84-4 8.5.1 Acute toxicity, oral Kamienski FX 1971 Toxicology lab report
sodium trimetaphosphate 8 7785-84-4 8.5.3 Acute toxicity, dermal Kamienski FX 1971 Toxicology lab report
sodium trimetaphosphate 8 7785-84-4 8.1.1 Skin irritation in vivo Kamienski FX 1971 Toxicology lab report
sodium trimetaphosphate 8 7785-84-4 8.2.1 eye irritation in vivo Kamienski FX 1971 Toxicology lab report
potassium polymetaphosphate N/A ? 8.5.1 Acute toxicity, oral Kamienski FX 1971 Toxicology lab report
potassium polymetaphosphate N/A ? 8.5.3 Acute toxicity, dermal Kamienski FX 1971 Toxicology lab report
potassium polymetaphosphate N/A ? 8.1.1 Skin irritation in vivo Kamienski FX 1971 Toxicology lab report
potassium polymetaphosphate N/A ? 8.2.1 eye irritation in vivo Kamienski FX 1971 Toxicology lab report
tetrapotassium pyrophosphate 15 7320-34-5 8.5.1 Acute toxicity, oral Kamienski FX 1971 Toxicology lab report
tetrapotassium pyrophosphate 15 7320-34-5 8.5.3 Acute toxicity, dermal Kamienski FX 1971 Toxicology lab report
tetrapotassium pyrophosphate 15 7320-34-5 8.1.1 Skin irritation in vivo Kamienski FX 1971 Toxicology lab report
tetrapotassium pyrophosphate 15 7320-34-5 8.2.1 eye irritation in vivo Kamienski FX 1971 Toxicology lab report
potassium tripolyphosphate 16 13845-36-8 8.5.1 Acute toxicity, oral Kamienski FX 1971 Toxicology lab report
potassium tripolyphosphate 16 13845-36-8 8.5.3 Acute toxicity, dermal Kamienski FX 1971 Toxicology lab report
potassium tripolyphosphate 16 13845-36-8 8.1.1 Skin irritation in vivo Kamienski FX 1971 Toxicology lab report
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-11
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
potassium tripolyphosphate 16 13845-36-8 8.2.1 eye irritation in vivo Kamienski FX 1971 Toxicology lab report
monopotassium phosphate 12 7778-77-0 8.5.1 Acute toxicity, oral Kamienski FX 1971 Toxicology lab report
monopotassium phosphate 12 7778-77-0 8.5.3 Acute toxicity, dermal Kamienski FX 1971 Toxicology lab report
monopotassium phosphate 12 7778-77-0 8.1.1 Skin irritation in vivo Kamienski FX 1971 Toxicology lab report
monopotassium phosphate 12 7778-77-0 8.2.1 eye irritation in vivo Kamienski FX 1971 Toxicology lab report
Magnesium phosphate (solution) 31 13092-66-5 8.5.1 Acute toxicity, oral Kamienski FX 1971 Toxicology lab report
Magnesium phosphate (solution) 31 13092-66-5 8.5.3 Acute toxicity, dermal Kamienski FX 1971 Toxicology lab report
Magnesium phosphate (solution) 31 13092-66-5 8.1.1 Skin irritation in vivo Kamienski FX 1971 Toxicology lab report
Magnesium phosphate (solution) 31 13092-66-5 8.2.1 eye irritation in vivo Kamienski FX 1971 Toxicology lab report
sodium aluminium phosphate 43 7785-88-8 8.2.1 eye irritation in vivo n/a n/a
sodium hexametaphosphate 10 68915-31-1 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX 1972 Toxicology lab report
dicalcium phosphate 22 7757-93-9 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX 1972 Toxicology lab report
dipotassium phosphate 13 7758--11-4 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX 1972 Toxicology lab report
disodium phosphate 3 7558-79-4 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX 1972 Toxicology lab report
ferric orthophosphate 27 10045-86-0 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX 1972 Toxicology lab report
insoluble sodium metaphosphate 11 10361-03-2 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX 1972 Toxicology lab report
monosodium phosphate 2 7558-80-7 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX 1972 Toxicology lab report
sodium trimetaphosphate 8 7785-84-4 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX 1972 Toxicology lab report
tricalcium phosphate 24 1306-06-5 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX 1972 Toxicology lab report
trimagnesium phosphate 30 7757-87-1 8.1.1 skin irritation in vivo Bullock CH and Kamienski FX 1972 Toxicology lab report
monocalcium phosphate 21 7758-23-8 8.1.1 Skin irritation in vivo Henderson L and Joiner RL 1974 Toxicology lab report
monocalcium phosphate 21 7758-23-8 8.8.1 Toxicokinetics Killenger JM 1986
Calcium phosphates, calcium sulfate and calcium carbonate bioavailability and disposition in rats.
dicalcium phosphate 22 7757-93-9 8.8.1 Toxicokinetics Killenger JM 1986
Calcium phosphates, calcium sulfate and calcium carbonate bioavailability and disposition in rats.
tricalcium phosphate 24 1306-06-5 8.8.1 Toxicokinetics Killenger JM 1986
Calcium phosphates, calcium sulfate and calcium carbonate bioavailability and disposition in rats.
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-12
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
calcium pyrophosphate 26 7790-76-3 8.1.1 Skin irritation in vivo Henderson L and Joiner RL 1974 Toxicology lab report
trisodium phosphate (doedecahydrate) 4 7601-54-9 8.2.1 eye irritation in vivo Glaza SM 1992
Primary eye irritation study of trisodium phosphate dodecahydrate (saturated solution at 22 degC) in rabbits
phosphoric acid 48 7664-38-2 8.1.1 Skin irritation in vivo Lewis CA 1979A dermal corrosion study in albino rabbits. Compound: MCTR-67-79
Phosphoric acid? 48 7664-38-2 8.2.1 eye irritation in vivo Imlay P and Parke G 1977
Report on rabbit eye irritation Compound: MCTR-192-77
Phosphoric acid? 48 7664-38-2 8.5.1 Acute toxicity, oralTerrel Y and Parke G 1977
Report on Oral LD50 in rats. Compound: MCTR-192-77
sodium tripolyphosphate 0 7758-29-4 8.1.1 Skin irritation in vivo Becker J and Parke G 1975
A primary dermal irritation study of MCTR-5-75 on abraded and nonabradedc skin of New Zealand albino rabbits
sodium tripolyphosphate 0 7758-29-4 8.2.1 eye irritation in vivo Becker J and Parke G 1975
The effects of MCTR-5-75 on the eye mucosa of New Zealand albino rabbits
ammonium polyphosphate 20 68333-79-9 8.5.1 Acute oral toxicity Cuthbert JA 1990AMGARD LR2: Acute toxicity (LD50) test in rats
ammonium polyphosphate 20 68333-79-9 8.5.3 Acute toxicity, dermal Cuthbert JA 1990AMGARD LR2: Acute dermal irritation test in rabbits
ammonium polyphosphate 20 68333-79-9 8.3 Skin senstisation Tomlinson PP 1993AMGARD LR2: Magnusson & Kligman maximisation study in the Guinea pig
ammonium polyphosphate 20 68333-79-9 8.5.1 Acute toxicity, oral Guest RL 1993AMGARD LR4: Acute oral toxicity (Limit test) in the rat
ammonium polyphosphate 20 68333-79-9 8.2.1 eye irritation in vivo Tomlinson PP 1993AMGARD LR2: Acute eye irritation test in the rabbit
ammonium polyphosphate 20 68333-79-9 8.5.3 Acute toxicity, dermal Guest RL 1993AMGARD LR4: acute dermal toxicity (Limit test) in the rat
ammonium polyphosphate 20 68333-79-9 8.3 Skin senstisation Tomlinson PP 1993AMGARD LR4: Magnusson & Kligman maximisation study in the guinea pig
ammonium polyphosphate 20 68333-79-9 8.5.3 Acute toxicity, dermal Tomlinson PP 1993AMGARD LR4: Acute dermal irritation test in the rabbit
ammonium polyphosphate 20 68333-79-9 8.2.1 eye irritation in vivo Tomlinson PP 1993AMGARD LR4: Acute eye irritation test in the rabbit
ammonium polyphosphate 20 68333-79-9 8.5.2 Acute toxicity, inhalation Tomlinson PP 1993
AMGARD MC(M): Acute inhalation toxicity study four-hour exposure (nose only) in the rat
ammonium polyphosphate 20 68333-79-9 8.5.3, Acute toxicity, dermal Snell K 1994AMGARD LR2: Acute dermal toxicity (Limit test) in the rat
ammonium polyphosphate 20 68333-79-9 8.4.1 Mutagenicity in bacteria Thompson PW 1995
AMGARD LR2: reverse mutation assay "AMES TEST" using Salmonella
typhimurium
ammonium polyphosphate 20 68333-79-9 8.3 Skin senstisation Cutherbert JA and Neilson L 1996
Three flame retardant formulations. A human skin patch test (46h exposure)
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-13
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
dipotassium phosphate 13 7758-11-4 8.2.1 eye irritation Terrel Y and Parke G 1975
The effects of MCTR-4-75 on the eye mucosa of New Zealand albino rabbits
dipotassium phosphate 13 7758-11-4 8.1. skin irritation in vivo Becker J and Parke G 1975
A primary dermal irritation study of MCTR-4-75 on abraded and nonabraded skin of New Zealand albino rabbits
dipotassium phosphate 13 7758-11-4 8.4 mutagenicity in bacteria Jagannath DR 1977 Mutagenicity evaluation of MCTR-256
phosphoric acid 48 7664-38-2 8.5.1 Acute toxicity, oral ? ? ?
phosphoric acid 48 7664-38-2 8.5.1 Acute toxicity, oralScholz and Weigand 1967/68
Toxikologische Prüfung von reinigerkomponenten
phosphoric acid 48 7664-38-2 ?Scholz and Weigand 1971? Pastöse Phosphorsäure. VP Kn 500
phosphoric acid 48 7664-38-2 8.1.1 Skin irritation in vivo (?) Weigand W 1985Phosorige Säure Prüng auf Hautreizung am Kaninchen
phosphoric acid 48 7664-38-2 8.5.3 Acute toxicity, dermal Imlay P and Parke G 1977
Report on the acute dermal toxicity of rabbits Compound: MCTR-192-77
phosphoric acid 48 7664-38-2 8.5.1 Acute toxicity, oralImlay P and Parke G 1977
Report on oral LD50 in rats. Compound: MCTR-192-77
phosphoric acid 48 7664-38-2 8.1.1 Skin irritation in vivo Imlay P and Parke G 1977
Report on primary dermal irritation study in rabbits. Compound: MCTR-192-77
phosphoric acid 48 7664-38-2 8.2.1 eye irritation Becker J and Parke G 1976
Report on rabbit eye irritation Compound: MCTR-51-76
phosphoric acid 48 7664-38-2 8.1.1 Skin irritation in vivoBecker J and Parke G 1976
Report on primary dermal irritation study in rabbits. Compound: MCTR-51-76
polyphosphoric acid 49 8017-16-1 8.5.1 Acute toxicity, oral Weigand W 1972 ?
polyphosphoric acid 49 8017-16-1 8.1.1 skin irritation in vivo ? 1973
Berict über die Prüfung der haut - und schleimhautverträglichkeit von 3 emulgatoren und einem reaktionsprodukt am kaninchen
tetrapotassium pyrophosphate 15 7320-34-5 8.2.1 eye irritation in vivo Parke G 1975The effects of MCTR-6-75 on the eye mucosa of New Zealand albino rabbits
tetrapotassium pyrophosphate 15 7320-34-5 8.1.1 skin irritation Becker J and Parke G 1975
A primary dermal irritation study of MCTR-6-75 on abraded and nonabraded skin of F New Zealand albino rabbits.
tripotassium phosphate 14 7778-53-2 8.2.1 eye irritation in vivo Parke G 1975The effects of MCTR-7-75 on the eye mucosa of New Zealand albino rabbits
Tripotassium phosphate 14 7778-53-2 8.5.1 Acute toxicity, oral Terrell Y and Parke G 1975
Acute oral toxicity in rats. Compound: MCTR-7-75
tripotassium phosphate 14 7778-53-2 8.1.1 skin irritation in vivo Becker J and Parke G 1975
A primary dermal irritation study of MCTR-7-75 on abraded and nonabraded skin of New Zealand albino rabbits
tripotassium phosphate 14 7778-53-2 8.4.1 Mutagenicity in bacteria Jagannath DR 1977 Mutagenicity evaluation of MCTR-258
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-14
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
monaluminium phosphate 39 13530-50-2 8.2.1 eye irritation in vivo Parke G 1975the effects of MCTR-2-75 on the eye mucosa of New Zealand albino rabbit
monaluminium phosphate 39 13530-50-2 8.1.1 skin irritation in vivo Becker J and Parke G 1975
A primary dermal irritation study of MCTR-2-75 on abraded and nonabraded skin of New Zealand albino rabbits
monaluminium phosphate 39 13530-50-2 8.2.1 eye irritation in vivo Parke G 1975the effects of MCTR-20-75 on the eye mucosa of New Zealand albino rabbit
monaluminium phosphate 39 13530-50-2 8.1.1 skin irritation in vivo Parke G 1975
A primary dermal irritation study of MCTR-20-75 on abraded and nonabraded skin of New Zealand albino rabbits
sodium aluminum phosphate 43 7785-88-8 8.6.2 subchronic, 90-day, oral Smith PS 197290-day subacute oral toxicity study with LEVAIR in albino rats
sodium aluminum phosphate 43 7785-88-8 8.6.2 subchronic, 90-day, oral Smith PS 197290-day subacute oral toxicity study with KASAL in albino rats
sodium aluminum phosphate 43 7785-88-8 8.6.2 subchronic, 90-day, oral Reyna MS 197390-day subacute oral toxicity study with LEVAIR in female albino rats
sodium aluminum phosphate 43 7785-88-8 8.6.2 subchronic, 90-day, oral Mastalski K. 197290-day subacute oral toxicity study with LEVAIR in Beagle dogs
sodium aluminum phosphate 43 7785-88-8 8.6.2 subchronic, 90-day, oral Mastalski K. 197290-day subacute oral toxicity study with KASAL in Beagle dogs
potassium pentahydrogen bis(phosphate) 55 14887-42-4 8.5.3 Acute toxicity, dermal Moore GE 2006
Acute dermal toxicity study in rats - Limit test
potassium pentahydrogen bis(phosphate) 55 14887-42-4 8.2.1 eye irritation in vivo Moore GE 2006 Primary eye irritation study in rabbits
potassium pentahydrogen bis(phosphate) 55 14887-42-4 8.5.1 Acute toxicity, oral Moore GE 2006 Acute toxicity up and down procedure
potassium pentahydrogen bis(phosphate) 55 14887-42-4 8.1.1 skin irritation in vivo Moore GE 2006 Primary skin irritation study in rabbits
potassium pentahydrogen bis(phosphate) 55 14887-42-4 Water solubility Mollandin G 2009
Determination of the water solubility of potassium pentahydrogen bis(phosphate)
potassium pentahydrogen bis(phosphate) 55 14887-42-4 Dissociation constant Fieseler A 2009
Determination of the dissociation constant of potassium pentahydrogen bis(phosphate) in water
relative density Fieseler A 2009
Determination of the relative density of potassium pentahydrogen bis(phosphate)
monoaluminum phosphate 39 13530-50-2 8.5.1 Acute toxicity, oral Kazimerierz Kita 2001 ?
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-15
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
monoaluminum phosphate 39 13530-50-2 8.5.3 Acute toxicity, dermal Kazimerierz Kita 2001 ?
monoaluminum phosphate 39 13530-50-2 8.1.1 skin irritation Kazimerierz Kita 2001 ?
Ammonium phosphate sulfate N/A 12593-60-1 9.1.3 Short--term toxicity testing on fish ? 2000
Acute toxicity of ammonium phosphate sulfate to the rainbow trout, Onchorhynchus mykiss, dertermined under static test conditions
Ammonium phosphate sulfate N/A 12593-60-1 8.5.1 Acute toxicity, oral ? 2000Acute oral toxicity up and down procedure in rats
diammonium phosphate 19 7783-28-0 9.1.2 Growth inhibition study in aquatic plants ? 2000
Toxicity of diammonium phosphate (DAP) to unicellular green alga, Selenastrum capricornutum
diammonium phosphate 19 7783-28-0 8.4.2 In vitro cytogenicity study in mammalian cells ? 2000In vitro mammalian chromosome abberation test
diammonium phosphate 19 7783-28-0 8.5.1 Acute toxicity, oral ? 2000Acute oral toxicity up and down procedure in rats
diammonium phosphate 19 7783-28-08.7.1 Screening for reproductive developmental toxicity ? 2002
4-week general toxicity and reproductive / development toxicity screening test
diammonium phosphate 19 7783-28-0 8.4.1 Mutagenicity in bacteria ? 2001 Bacterial reverse mutation assay
diammonium phosphate 19 7783-28-0 8.5.3 Acute toxicity, dermal ? 2000Acute dermal toxicity study in rats - Limit test
Liquid ammonium polyphosphate 20 68333-79-9 9.1.3 Short-term toxicity testing on fish ? 2000
Acute toxicity of liquid polyphosphate to the rainbow trout, Onchorhynchus mykiss, dertermined under static test conditions
Liquid ammonium polyphosphate 20 68333-79-9 8.5.1 Acute toxicity, oral ? 2000Acute oral toxicity up and down procedure in rats
monoammonium phosphate 18 7722-76-1 8.5.3 Acute toxicity, dermal ? 2000Acute dermal toxicity study in rats - Limit test
monoammonium phosphate 18 7722-76-1 9.1.3 Short-term toxicity testing on fish ? 2000
Acute toxicity of monoammonium phosphate to the rainbow trout, Onchorhynchus mykiss, dertermined under static test conditions
monoammonium phosphate 18 7722-76-1 8.5.1 Acute toxicity, oral ? 2000Acute oral toxicity up and down procedure in rats
TSP N/A 65995-95-4 9.1.2 Growth inhibition study in aquatic plants Aufderheide JA, Bussard JB 2000
Toxicity of granular triple sugar phosphate (GTSP) to unicellular green alga, Selenastrum capricornutum
(OECD 201)
TSP N/A 65995-95-5 8.4.2 In vitro cytogenicity study in mammalian cells Gudi R & Brown C 2001
In vitro mammalian chromosome abberation test
TSP N/A 65995-95-6 8.4.1 Mutagenicity in bacteriaWagner VO & Klug ML 2001 Bacterial reverse mutation assay
TSP N/A 65995-95-78.7.1 Screening for reproductive developmental toxicity Dent MP 2002
4-week general toxicity and reproductive / development toxicity screening test
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-16
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
STPP 0 7758-29-4 9.1.3 Short -term toxicity to fish ? ? Short-term toxicity to fish
STPP 0 7758-29-4 8.1.1 Skin Irritation/ Corrosion In-vivo ? ? Skin irritation
STPP 0 7758-29-4 8.1.1 Skin Irritation/ Corrosion In-vivo ? ? Skin irritation
STPP 0 7758-29-4 8.1.1 Skin Irritation/ Corrosion In-vivo ? ? Skin irritation
STPP 0 7758-29-4 8.2.2 Eye Irritation/ Corrosion: In-vivo ? ? Eye irritation rabbits
STPP 0 7758-29-4 8.2.2 Eye Irritation/ Corrosion: In-vivo ? ? Eye irritation rabbits
STPP 0 7758-29-4 8.3 Skin sensitisation ? ? Clinical sensitisation
STPP 0 7758-29-4 8.3 Skin senstisation ? ? Clinical sensitisation
STPP 0 7758-29-4 8.3 Skin senstisation ? ? Clinical sensitisation
STPP 0 7758-29-4 8.3 Skin senstisation ? ? Clinical sensitisation
STPP 0 7758-29-4 8.3 Skin senstisation ? ? Clinical sensitisation
STPP 0 7758-29-4 8.3 Skin senstisation ? ? Clinical sensitisation
STPP 0 7758-29-4 8.3 Skin senstisation ? ? Clinical sensitisation
STPP 0 7758-29-4 8.3 Skin senstisation ? ? Clinical sensitisation
STPP 0 7758-29-4 8.3 Skin senstisation ? ? Clinical sensitisation
STPP 0 7758-29-4 8.5.1 Acute Toxicity: Oral ? ? Acute toxicity
STPP 0 7758-29-4 8.5.1 Acute Toxicity: Oral ? ? Acute toxicity
STPP 0 7758-29-4 8.5.1 Acute Toxicity: Oral ? ? Acute toxicity
STPP 0 7758-29-4 8.5.1 Acute Toxicity: Oral ? ? Acute toxicity
STPP 0 7758-29-4 8.5.1 Acute Toxicity: Oral ? ? Acute toxicity
STPP 0 7758-29-4 8.6.1 short-term repeated dose, oral, 28-day ? ? Short-term repeated dose
STPP 0 7758-29-4 8.6.2 subchronic, 90-day, oral ? ? Subchronic toxicity
STPP 0 7758-29-4 8.6.2 subchronic, 90-day, oral ? ? Subchronic toxicity
STPP 0 7758-29-4 8.6.2 subchronic, 90-day, oral ? ? Subchronic toxicity
STPP 0 7758-29-4
8.6.1 Short-term Repeated Dose Toxicity: Inhalation
? ? Short-term repeated dose
STPP 0 7758-29-4 8.6.1 short-term repeated dose, oral, 28-day ? ? Short-term repeated dose
STPP 0 7758-29-4 8.9.1 Chronic toxicity Dermal ? ? Carcinogenicity
STPP 0 7758-29-4 8.9.2 Carcinogenicity study- dermal ? ? Carcinogenicity
dipotassium phosphate 13 7758-11-4 OECD 422: 28-day repeated dose and reprotoxicity study Shim YH 2005
OECD 422: 28-day repeated dose and reprotoxicity study
phosphoric acid 48 Reverse mutation assay (AMES)Choi S.A, Hong E.K 2008 AMES test
STPP 0 7758-29-4 Water Solubility 2009 Water solubility
Sodium dihydrogenorthophosphate 2 7558-80-7 Water Solubility 2009 Water Solubility
Sodium dihydrogenorthophosphate 2 7558-80-7 Melting point 2009 Melting point
Sodium dihydrogenorthophosphate 2 7558-80-7 8.3 Skin sensitisation 2009 Skin sensitisation
Sodium dihydrogenorthophosphate 2 7558-80-7 8.5.1 Acute toxicity, oral 2009 Acute toxicity, oral
Sodium dihydrogenorthophosphate 2 7558-80-7 relative density 2010 relative density
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-17
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
Disodium hydrogenorthophosphate 3 7558-79-4 Water Solubility 2009 Water Solubility
Disodium hydrogenorthophosphate 3 7558-79-4 Melting point 2009 Melting point
Disodium hydrogenorthophosphate 3 7558-79-4 8.5.1 Acute toxicity, oral 2009 Acute toxicity, oral
Trisodium orthophosphate 4 7601-54-9 Water Solubility 2009 Water Solubility
Trisodium orthophosphate 4 7601-54-9 Melting point 2009 Melting point
Trisodium orthophosphate 4 7601-54-9 8.5.1 Acute toxicity, oral 2009 Acute toxicity, oral
monopotassium phosphate 12 7778-77-0 Boiling point 2009 Boiling point
monopotassium phosphate 12 7778-77-0 Vapour pressure 2009 Vapour pressure
monopotassium phosphate 12 7778-77-0 Water Solubility 2009 Water Solubility
monopotassium phosphate 12 7778-77-0 relative density 2010 relative density
dipotassium phosphate 13 7758-11-4 Melting point 2009 Melting point
dipotassium phosphate 13 7758-11-4 Water Solubility 2009 Water Solubility
dipotassium phosphate 13 7758-11-4 relative density 2010 relative density
dipotassium phosphate 13 7758-11-4 Activated sludge respiration inhibition 2010 Activated sludge respiration inhibition
dipotassium phosphate 13 7758-11-4 Acute oral toxicity 2010 acute oral toxicity
tripotassium orthophosphate 14 7778-53-2 Water Solubility 2009 Water solubility
Calcium bis(dihydrogenorthophosphate) / monocalcium phosphate 21 7758-23-8 Melting point 2009 Melting point
Calcium bis(dihydrogenorthophosphate) / monocalcium phosphate 21 7758-23-8 Water Solubility 2009 Water Solubility
Calcium bis(dihydrogenorthophosphate) / monocalcium phosphate 21 7758-23-8 In vitro eye irritation 2009 Eye Irritation, in vitro
Calcium bis(dihydrogenorthophosphate) / monocalcium phosphate 21 7758-23-8 Eye irritation, in vivo 2010 eye irritation in vivo
Calcium bis(dihydrogenorthophosphate) / monocalcium phosphate 21 7758-23-8 Acutr inhalation 2010 Acute toxicity: inhalation
calcium hydrogenorthophosphate / Dicalcium phosphate 22 7757-93-9 Melting point 2009 Melting point
calcium hydrogenorthophosphate / Dicalcium phosphate 22 7757-93-9 Water Solubility 2009 Water Solubility
calcium hydrogenorthophosphate / Dicalcium phosphate 22 7757-93-9 8.2.2 Eye Irritation, in vitro 2009 Eye Irritation, in vitro
Tricalcium bis(orthophosphate) 23 7758-87-4 Melting point 2009 Melting point
Tricalcium bis(orthophosphate) 23 7758-87-4 Water Solubility 2009 Water Solubility
Tricalcium bis(orthophosphate) 23 7758-87-4 8.2.2 Eye Irritation, in vitro 2009 Eye Irritation, in vitro
Tricalcium bis(orthophosphate) 23 7758-87-4 8.1.1 Skin irritation, in vitro 2009 Skin irritation, in vitro
Tricalcium bis(orthophosphate) 23 7758-87-4 8.1.1 Skin corrosion, in vitro 2009 Skin corrosion, in vitro
Tricalcium bis(orthophosphate) 23 7758-87-4 8.5.1 Acute toxicity, oral 2009 Acute toxicity, oral
Tricalcium bis(orthophosphate) 23 7758-87-4 Eye irritation, in vivo 2010 eye irritation in vivo
tricalcium phosphate 24 12167-74-7 Water Solubility 2009 Water solubility
tricalcium phosphate 24 12167-74-7 8.4.3 In vitro gene mutation study in mammalian cells 2009 Mouse Lymphoma assay
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-18
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
Dimagnesium phosphate-3-hydrate 29 7757-86-0 Melting point 2009 Melting point
Dimagnesium phosphate-3-hydrate 29 7757-86-0 Water Solubility 2009 Water Solubility
Dimagnesium phosphate-3-hydrate 29 7757-86-0 8.2.2 Eye Irritation, in vitro 2009 Eye Irritation, in vitro
Dimagnesium phosphate-3-hydrate 29 7757-86-0 8.1.1 Skin irritation, in vitro 2009 Skin irritation, in vitro
Dimagnesium phosphate-3-hydrate 29 7757-86-0 8.1.1 Skin corrosion, in vitro 2009 Skin corrosion, in vitro
Dimagnesium phosphate-3-hydrate 29 7757-86-0 8.5.1 Acute toxicity, oral 2009 Acute toxicity, oral
Trimagnesium phosphate-4-hydrate 30 7757-87-1 Melting point 2009 Melting point
Trimagnesium phosphate-4-hydrate 30 7757-87-1 Water Solubility 2009 Water Solubility
Trimagnesium phosphate-4-hydrate 30 7757-87-1 8.4.1 In vitro gene mutation study in bacteria 2009 AMES
Trimagnesium phosphate-4-hydrate 30 7757-87-1 8.4.2. In vitro cytogenicity assay 2009 Chromosomal abberation test
Trimagnesium phosphate-4-hydrate 30 7757-87-1 8.4.3 In vitro gene mutation study in mammalian cells 2009 Muse Lymphoma assay
Magnesium bis(dihydrogenorthophosphate) 31 13092-66-5 Melting point 2009 Melting point
Magnesium bis(dihydrogenorthophosphate) 31 13092-66-5 Water Solubility 2009 Water Solubility
iron orthophosphate 27 10045-86-0 Melting point 2009 Melting point
iron orthophosphate 27 10045-86-0 Water Solubility 2009 Water Solubility
Trimanganese bis(orthophosphate) 33 14154-09-7 Melting point 2009 Melting point
Trimanganese bis(orthophosphate) 33 14154-09-7 Water Solubility 2009 Water Solubility
Manganese bis(dihydrogen phosphate) 34 18718-07-5 Melting point 2009 Melting point
Manganese bis(dihydrogen phosphate) 34 18718-07-5 Water Solubility 2009 Water Solubility
Dimanganese phosphate-2-hydrate 35 51349-94-1 Melting point 2009 Melting point
Dimanganese phosphate-2-hydrate 35 51349-94-1 Water Solubility 2009 Water Solubility
Tricopper bis(orthophosphate) 36 7798-23-4 Melting point 2009 Melting point
Tricopper bis(orthophosphate) 36 7798-23-4 Water Solubility 2009 Water solubility
Dicopper hydroxide phosphate 38 12158-74-6 Melting point 2009 Melting point
Dicopper hydroxide phosphate 38 12158-74-6 Water Solubility 2009 Water Solubility
Boron orthophosphate 44 13308-51-5 Melting point 2009 Melting point
Boron orthophosphate 44 13308-51-5 Water Solubility 2009 Water Solubility
Aluminium tris dihydrogenphosphate 39 13530-50-2 Melting point 2009 Melting point
Aluminium tris dihydrogenphosphate 39 13530-50-2 Water Solubility 2009 Water Solubility
Aluminium tris dihydrogenphosphate 39 13530-50-2 Relative density 2010 Relative density
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-19
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
Aluminium tris dihydrogenphosphate 39 13530-50-2 Acute inhalation toxicity 2010 Acute toxicity: inhalation
Aluminium orthophosphate 40 7784-30-7 Melting point 2009 Melting point
Aluminium orthophosphate 40 7784-30-7 Water Solubility 2009 Water Solubility
Aluminium orthophosphate 40 7784-30-7 8.2.2 Eye Irritation, in vitro 2009 Eye Irritation, in vitro
Aluminium orthophosphate 40 7784-30-7 8.2.2 Eye Irritation, in vivo 2009 Eye Irritation, in vivo
Aluminium orthophosphate 40 7784-30-7 8.1.1 Skin irritation, in vitro 2009 Skin irritation, in vitro
Aluminium orthophosphate 40 7784-30-7 8.4.1 In vitro gene mutation study in bacteria 2009 AMES
Aluminium orthophosphate 40 7784-30-7 8.4.2. In vitro cytogenicity assay 2009 Chromosomal abberation test
Aluminium orthophosphate 40 7784-30-7 8.4.3 In vitro gene mutation study in mammalian cells 2009 Muse Lymphoma assay
Aluminium orthophosphate 40 7784-30-7 8.1.1 Skin corrosion, in vitro 2009 Skin corrosion, in vitro
Aluminium orthophosphate 40 7784-30-7 8.5.1 Acute toxicity, oral 2009 Acute toxicity, oral
Aluminium orthophosphate 40 7784-30-7 Activated sludge respiration inhibition 2010 Activated sludge respiration inhibition
sodium aluminium phosphate 1:3:8 43 7785-88-8 Melting point 2009 Melting point
sodium aluminium phosphate 1:3:8 43 7785-88-8 Water Solubility 2009 Water Solubility
sodium aluminium phosphate 1:3:8 43 7785-88-8 Relative density 2010 Relative density
sodium aluminium phosphate 3:2:8 43 7785-88-8 Melting point 2009 Melting point
sodium aluminium phosphate 3:2:8 43 7785-88-8 Water Solubility 2009 Water Solubility
Disodium dihydrogen pyrophosphate 5 7758-16-9 Water Solubility 2009 Water Solubility
Disodium dihydrogen pyrophosphate 5 7758-16-9 Melting point 2009 Melting point
Disodium dihydrogen pyrophosphate 5 7758-16-9 8.3 Skin sensitisation 2009 Skin sensitisation
Disodium dihydrogen pyrophosphate 5 7758-16-9 8.2.2 Eye irritation , in vitro 2009 Eye irritation, in vitro
Disodium dihydrogen pyrophosphate 5 7758-16-9 eye irritation, in vivo 2010 eye irritation, in vivo
Disodium dihydrogen pyrophosphate 5 7758-16-9 Relative density 2010 Relative density
Trisodium hydrogen diphosphate 6 14691-80-6 Melting point 2009 Melting point
Trisodium hydrogen diphosphate 6 14691-80-6 Water Solubility 2009 Water Solubility
Trisodium hydrogen diphosphate 6 14691-80-6 8.2.2 Eye Irritation, in vitro 2009 8.2.2 Eye Irritation, in vitro
Trisodium hydrogen diphosphate 6 14691-80-6 8.1.1 Skin irritation, in vitro 2009 8.1.1 Skin irritation, in vitro
Trisodium hydrogen diphosphate 6 14691-80-6 8.5.1 Acute toxicity, oral 2009 8.5.1 Acute toxicity, oral
Trisodium hydrogen diphosphate 6 14691-80-6 OECD 431 In vitro skin corrosion study 2010 skin corrosion in vitro
tetrasodium pyrophosphate 7 7722-88-5 Water Solubility 2009 Water Solubility
tetrasodium pyrophosphate 7 7722-88-5 8.5.1 Acute toxicity, oral 2009 8.5.1 Acute toxicity, oral
tetrasodium pyrophosphate 7 7722-88-5 Eye irritation, in vitro - BCOP 2010 Eye irritation in vitro
tetrasodium pyrophosphate 7 7722-88-5 Relative density 2010 Relative density
tetrasodium pyrophosphate 7 7722-88-5 eye irritation, in vivo 2010 eye irritation, in vivo
tetrapotassium pyrophosphate 15 7320-34-5 Water Solubility 2009 Water solubility
tetrapotassium pyrophosphate 15 7320-34-5 Relative density 2010 Relative density
calcium dihydrogenpyrophosphate 25 14866-19-4 Melting point 2009 Melting point
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-20
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
calcium dihydrogenpyrophosphate 25 14866-19-4 Water Solubility 2009 Water Solubility
Dicalcium pyrophosphate 26 7790-76-3 Melting point 2009 Melting point
Dicalcium pyrophosphate 26 7790-76-3 Water Solubility 2009 Water Solubility
Dicalcium pyrophosphate 26 7790-76-3 Skin corrosion - in vitro; screening 2011 skin corrosion in vitro
Tetrairon tris(pyrophosphate) 28 10058-44-3 Melting point 2009 Melting point
Tetrairon tris(pyrophosphate) 28 10058-44-3 Water Solubility 2009 Water Solubility
copper (II)-pyrophosphate 37 10102-90-6 Melting point 2009 Melting point
copper (II)-pyrophosphate 37 10102-90-6 Water Solubility 2009 Water Solubility
magnesium pyrophosphate 57 13446-24-7 Water Solubility 2009 Water solubility
magnesium pyrophosphate 57 13446-24-7 in vitro skin corrosion 2011 in vitro skin corrosion
Pentapotassium triphosphate 16 13845-36-8 Water Solubility 2009 Water Solubility
Pentapotassium triphosphate 16 13845-36-8 Melting point 2009 Melting point
Pentapotassium triphosphate 16 13845-36-8 8.5.1 Acute toxicity, oral 2009 Acute toxicity, oral
Pentapotassium triphosphate 16 13845-36-8 Relative density 2010 Relative density
Sodium potassium tripolyphosphate / pentapotassium pentasodium bis(triphosphate) 46 24315-83-1 Melting point 2009 Melting point
Sodium potassium tripolyphosphate / pentapotassium pentasodium bis(triphosphate) 46 24315-83-1 Water Solubility 2009 Water solubility
Sodium potassium tripolyphosphate / pentapotassium pentasodium bis(triphosphate) 46 24315-83-1 8.5.1 Acute toxicity, oral 2009 Acute toxicity, oral
Sodium potassium tripolyphosphate / pentapotassium pentasodium bis(triphosphate) 46 24315-83-1 8.1.1 Skin irritation, in vitro 2009 Skin irritation, in vitro
Sodium potassium tripolyphosphate / pentapotassium pentasodium bis(triphosphate) 46 24315-83-1 8.1.1 Skin corrosion, in vitro 2009 Skin corrosion, in vitro
Sodium potassium tripolyphosphate / pentapotassium pentasodium bis(triphosphate) 46 24315-83-1 8.2.2 Eye Irritation, in vitro 2009 Eye Irritation, in vitro
Aluminium tripolyphosphate 41 13939-25-8 Melting point 2009 Melting point
Aluminium tripolyphosphate 41 13939-25-8 Water Solubility 2009 Water Solubility
Trisodium trimetaphosphate 8 7785-84-4 Melting point 2009 Melting point
Trisodium trimetaphosphate 8 7785-84-4 Water Solubility 2009 Water Solubility
Trisodium trimetaphosphate 8 7785-84-4 Hydrolysis as a function of pH 2009 Hydrolysis as a function of pH
Trisodium trimetaphosphate 8 7785-84-4 Oxidising properties expert statement 2009 Oxidising properties expert statement
Trisodium trimetaphosphate 8 7785-84-4 Explosivity expert statement 2009 Explosivity expert statement
Trisodium trimetaphosphate 8 7785-84-4 8.5.1 Acute oral toxicity 2009 Acute oral toxicity
Trisodium trimetaphosphate 8 7785-84-4 8.3 Skin sensitisation 2009 Skin sensitisation
Trisodium trimetaphosphate 8 7785-84-4 Relative density 2010 relative density
Sodium metaphosphate 10 10124-56-8 Water Solubility 2009 Water Solubility
Sodium metaphosphate 10 10124-56-8 Melting point 2009 Melting point
Sodium metaphosphate 10 10124-56-8 Water Solubility 2009 Water Solubility
Sodium metaphosphate 10 10124-56-8 Hydrolysis as a function of pH 2009 Hydrolysis as a function of pH
Sodium metaphosphate 10 10124-56-8 Oxidising properties expert statement 2009 Oxidising properties expert statement
Sodium metaphosphate 10 10124-56-8 Explosivity expert statement 2009 Explosivity expert statement
Sodium metaphosphate 10 10124-56-8 8.3 Skin sensitisation 2009 Skin sensitisation
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-21
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
Sodium metaphosphate 10 10124-56-8 8.5.1 Acute oral toxicity 2009 Acute oral toxicity
Sodium metaphosphate 10 10124-56-8 Relative density 2010 Relative density
Sodium metaphosphate 10 10124-56-8 Acute toxicity to rainbow trout 2010 Acute toxicity to rainbow trout
Sodium metaphosphate 10 10124-56-8 Algal growth inhibition 2010 Algal growth inhibition
Sodium metaphosphate 10 10124-56-8 Activated sludge respiration inhibition 2010 Activated sludge respiration inhibition
Disodium fluorophosphate 47 10163-15-2 Melting point 2009 Melting point
Disodium fluorophosphate 47 10163-15-2 Water Solubility 2009 Water Solubility
Disodium fluorophosphate 47 10163-15-2 Hydrolysis as a function of pH 2009 Hydrolysis as a function of pH
Disodium fluorophosphate 47 10163-15-2 Oxidising properties expert statement 2009 Oxidising properties expert statement
Disodium fluorophosphate 47 10163-15-2 Explosivity expert statement 2009 Explosivity expert statement
Disodium fluorophosphate 47 10163-15-2 8.3 Skin sensitisation 2009 Skin sensitisation
Disodium fluorophosphate 47 10163-15-2 8.1.1 Skin corrosion in vitro 2009 Skin irritation in vitro
Disodium fluorophosphate 47 10163-15-2 8.1.1 Skin corrosion in vitro 2009 Skin corrosion in vitro
Disodium fluorophosphate 47 10163-15-2 8.2.2 Eye irritation in vitro 2009 Eye irritation in vitro
Disodium fluorophosphate 47 10163-15-2 8.4.1 In vitro gene mutation study in bacteria 2009 AMES
Disodium fluorophosphate 47 10163-15-2 8.4.3 In vitro gene mutation study in mammalian cells 2009 Mouse Lymphoma assay
Disodium fluorophosphate 47 10163-15-2 7.4 Relative Density 2010 7.4 Relative Density
Disodium fluorophosphate 47 10163-15-2 Acute toxicity to rainbow trout 2010 Acute toxicity to rainbow trout
Disodium fluorophosphate 47 10163-15-2 Acute toxicity to Daphnia magna 2010 Acute toxicity to Daphnia magna
Disodium fluorophosphate 47 10163-15-2 Algal growth inhibition 2010 Algal growth inhibition
Disodium fluorophosphate 47 10163-15-2 Activated sludge respiration inhibitin 2010 Activated sludge respiration inhibitin
Disodium fluorophosphate 47 10163-15-2 Soil adsorption coefficient 2010 Soil adsorption coefficient
Disodium fluorophosphate 47 10163-15-2 OECD 422 - range finder 2010 OECD 422 - range finder
Disodium fluorophosphate 47 10163-15-2 OECD 422 -FULL STUDY 2010 OECD 422 -FULL STUDY
Disodium fluorophosphate 47 10163-15-2 Eye irritation, in vivo 2010 Eye irritation, in vivo
Disodium fluorophosphate 47 10163-15-2 acute toxicity: inhalation 2010 Acute toxicity: inhalation
All substances Dissociation constant 2009 Dissociation constant
Group 1: orthophosphates Oxidising properties expert statement 2009 Oxidising properties expert statement
Group 1: orthophosphates Explosivity expert statement 2009 Explosivity expert statement
TBC -Group 2: diphosphates Hydrolysis as a function of pH 2009 Hydrolysis as a function of pH
Group 2: diphosphates Oxidising properties expert statement 2009 Oxidising properties expert statement
Group 2: diphosphates Explosivity expert statement 2009 Explosivity expert statement
TBC -Group 3: triphosphates Hydrolysis as a function of pH 2009 Hydrolysis as a function of pH
Group 2: triphosphates Oxidising properties expert statement 2009 Oxidising properties expert statement
Group 2: triphosphates Explosivity expert statement 2009 Explosivity expert statement
phosphoric acid 48 Reverse mutation assay (AMES) 2010 AMES
phosphoric acid 48 8.4.3 In vitro gene mutation study in mammalian cells 2010 Mouse Lymphoma assay
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-22
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
HiPeak - mixtue of MKP and DKP N/A N/A 6.1.1. Short-term toxicity to fish Priestly S 2010 Short-term toxicity to fish
HiPeak - mixtue of MKP and DKP N/A N/A 6.1.3 Short-term toxicity to invertebrates Priestly S 20106.1.3 Short-term toxicity to invertebrates
HiPeak - mixtue of MKP and DKP N/A N/A 6.1.5 Toxicity to aqautic algae and cyanobacteria vryenhoef H 20106.1.5 Toxicity to aqautic algae and cyanobacteria
Trisodium trimetaphosphate 8 7785-84-4 Acute toxicity to Daphnia magna Weber B 2010 Acute toxicity to Daphnia magna
Trisodium trimetaphosphate 8 7785-84-4 Algal growth inhibition Weber B 2010 Algal growth inhibition
phosphoric acid 48 AMES Choi SA 2008 In vitro gene mutation in bacterial cells
reaction mass of MCP and DCP 60 Melting point 2010 Melting point
reaction mass of MCP and DCP 60 Relative density 2010 Relative density
reaction mass of MCP and DCP 60 Water Solubility 2010 Water Solubility
reaction mass of MCP and DCP 60 Acute toxicity: oral 2010 acute toxicity: oral
reaction mass of MCP and DCP 60 in vitro skin irritation 2010 in vitro skin irritation
reaction mass of MCP and DCP 60 Ex vivo skin corrosion 2010 Ex vivo skin corrosion
reaction mass of MCP and DCP 60 In vitro eye irritation 2010 In vitro eye irritation
reaction mass of MCP and DCP 60 Acute eye irritation 2010 Acute eye irritation
iron orthophosphate 27 10045-86-0 Relative density 2011 Relative density
iron orthophosphate 27 10045-86-0 Activated Sludge Respiration Inhibition 2011 Activated Sludge Respiration Inhibition
iron orthophosphate 27 10045-86-0 Acute inhalation toxicity 2011 Acute inhalation toxicity
iron orthophosphate 27 10045-86-0 Skin sensitisation 2011 Local lymph node assay
iron orthophosphate 27 10045-86-0Mouse Lymphoma Assay (gene mutation in mammalian cells) 2011
Mouse Lymphoma Assay (gene mutation in mammalian cells)
iron orthophosphate 27 10045-86-0 Acute oral toxicity 2011 Acute oral toxicity
iron orthophosphate 27 10045-86-0 in vitro skin corrosion 2011 in vitro skin corrosion
iron orthophosphate 27 10045-86-0 in vitro skin irritancy 2011 in vitro skin irritancy
iron orthophosphate 27 10045-86-0 in vitro eye irritancy 2011 in vitro eye irritancy
iron orthophosphate 27 10045-86-0 ex-vivo REET 2011 ex-vivo REET
iron orthophosphate 27 10045-86-0 Acute eye 2011 Acute eye
iron orthophosphate 27 10045-86-0 Agal growth inhibition 2011 Agal growth inhibition
Diphosphric acid, sodium salt 5 7758-16-9 8.5.1 Acute toxicity, oral ? 2009 Acute oral toxicity
iron orthophosphate /NEU 1165M (iron (III) phosphate) 27 10045-86-0 8.5.3. Acute dermal toxicity Untenwiehe M 1996
Assesment of Dermal toxicity with NEU 1165 M in the rat
iron orthophosphate /NEU 1165M (iron (III) phosphate) 27 10045-86-0 8.2.1 Eye irritation in vivo Eye irritation in vivo
iron orthophosphate /NEU 1165M (iron (III) phosphate) 27 10045-86-0 8.5.1 Acute oral toxicity Acute oral toxicty
iron orthophosphate /NEU 1165M (iron (III) phosphate) 27 10045-86-0 Acute toxicity to birds Acute toxicity to birds
iron orthophosphate /NEU 1165M (iron (III) phosphate) 27 10045-86-0 9.4.1. Acute toxicty to soil invertebrates Acute toxicty to soil invertebrates
iron orthophosphate /NEU 1165M (iron (III) phosphate) 27 10045-86-0 9.4.1. Acute toxicty to soil invertebrates Acute toxicty to soil invertebrates
iron orthophosphate /NEU 1165M (iron (III) phosphate) 27 10045-86-0 7.10. flammability Untenwiehe M 1996 Flammability
iron orthophosphate /NEU 1165M (iron (III) phosphate) 27 10045-86-0 8.1.1 Primary skin irritation Primary skin irritation
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-23
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
iron orthophosphate / Ferric phosphate 27 10045-86-0 8.1.1 Primary skin irritation Berndt A 2000 Primary skin irritation / corrosion study
iron orthophosphate /NEU 1165M (iron (III) phosphate) 27 10045-86-0 9.4.1. Acute toxicty to soil invertebrates Acute toxicty to soil invertebrates
iron orthophosphate / Eisen (III)-phosphate (ferric(III) phosphate . 4H20) 27 10045-86-0 9.1.5. Long-term toxicity to Daphnia Heintze A 1997 Long-term toxicity to Daphnia
iron orthophosphate / Eisen (III)-phosphate (ferric(III) phosphate . 4H20) 27 10045-86-0 9.1.3. Short-term toxicity testing on fish Heintze A 1997 Short-term toxicity testing on fish
iron orthophosphate / Eisen (III)-phosphate (ferric(III) phosphate . 4H20) 27 10045-86-0 9.1.2 Growth inhibition study in aquatic plants Dengler D 1997 Growth inhibition study in aquatic plants
Ferric phosphate 27 10045-86-0 Acute toxicity, oral Berndt A, 1999
Assessment of acute oral toxicity with Ferric phosphate in the rat (acute toxic class method)
Ferric phosphate 27 10045-86-0 Eye irritation Berndt A, 2000 Eye irritation / corrosion in vivo
disodium dihydrogen pyrophosphate 5 14691-80-6 Acute dermal toxicity (OECD 402) Unknown 2002 Acute dermal toxicity (OECD 402)
disodium dihydrogen pyrophosphate 5 14691-80-6In vitro genen mutation in bacteria (AMES) (OECD 471) Unknown 2002
In vitro genen mutation in bacteria (AMES) (OECD 471)
disodium dihydrogen pyrophosphate 5 14691-80-6 In vitro chromosomal abberation study (OECD 473) Unknown 2002In vitro chromosomal abberation study (OECD 473)
disodium dihydrogen pyrophosphate 5 14691-80-6 Aquatic toxicity to fish (OECD ?) Unknown 2002 Aquatic toxicity to fish (OECD ?)
disodium dihydrogen pyrophosphate 5 14691-80-6 Aquatic toxicity to invertebrates (OECD ?) Unknown 2002Aquatic toxicity to invertebrates (OECD ?)
calcium hydrogenorthophosphate 22 7757-93-9 Acute oral toxicity (OECD 401) Unknown2006/20
08 Acute oral toxicity (OECD 401)
calcium hydrogenorthophosphate 22 7757-93-9In vitro genen mutation in bacteria (AMES) (OECD 471) Unknown
2006/2008
In vitro genen mutation in bacteria (AMES) (OECD 471)
calcium hydrogenorthophosphate 22 7757-93-9 In vitro chromosomal abberation study (OECD 473) Unknown2006/20
08In vitro chromosomal abberation study (OECD 473)
calcium hydrogenorthophosphate 22 7757-93-9 Aquatic toxicity to fish (OECD ?) Unknown2006/20
08 Aquatic toxicity to fish (OECD ?)
calcium hydrogenorthophosphate 22 7757-93-9 Aquatic toxicity to invertebrates (OECD ?) Unknown2006/20
08Aquatic toxicity to invertebrates (OECD ?)
tricalcium bis(orthophosphate) 23 7758-87-4 in vivo mammalian mouse micronucleus Unknown 2005 in vivo mammalian mouse micronucleus
tricalcium bis(orthophosphate) 23 7758-87-4 Aquatic toxicity to fish (OECD ?) Unknown 2005 Aquatic toxicity to fish (OECD ?)
tripotassium orthophosphate 14 7778-53-2 in vivo mammalian mouse micronucleus Unknown 2007 in vivo mammalian mouse micronucleus
tripotassium orthophosphate 14 7778-53-2 Aquatic toxicity to fish (OECD ?) Unknown 2007 Aquatic toxicity to fish (OECD ?)
tripotassium orthophosphate 14 7778-53-2 Aquatic toxicity to invertebrates (OECD ?) Unknown 2007Aquatic toxicity to invertebrates (OECD ?)
trisodium orthophosphate 4 7601-54-9In vitro genen mutation in bacteria (AMES) (OECD 471) Unknown 2007
In vitro genen mutation in bacteria (AMES) (OECD 471)
tetrasodium pyrophosphate 7 7722-88-5 Acute oral toxicity (up and down procedure) Villigran A 2010 Acute oral toxicity
magnesium dihydrogen pyrophosphate 58 20768-12-1 Acute oral toxicity - Class method (OECD 423) Entzian K 2011Budeheim Bioserv Magnesium pyro IP58 tests report 2010: Acute oral
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-24
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
magnesium dihydrogen pyrophosphate 58 20768-12-1 Genotoxicity (mouse lymphoma assay) Entzian K 2011Budeheim Bioserv Magnesium pyro IP58 tests report 2010: Genotox
magnesium dihydrogen pyrophosphate 58 20768-12-1 Skin irritation in vivo Entzian K 2011Budeheim Bioserv Magnesium pyro IP58 tests report 2010: skin irritation
magnesium dihydrogen pyrophosphate 58 20768-12-1 Acute eye irritation in vivo Entzian K 2011Budeheim Bioserv Magnesium pyro IP58 tests report 2010: eye irritation
magnesium dihydrogen pyrophosphate 58 20768-12-1 Skin corrosion - in vitro; screening Warren N 2011 Skin corrosion in vitro
Dicopper hydroxide phosphate 38 12158-74-6 Acute oral toxicity - OECD 423 Entzian K 2011Budeheim Bioserv dicopper phosphate IP38 tests report 2010: acute oral
Dicopper hydroxide phosphate 38 12158-74-6 Genotoxicity (mouse lymphoma assay) Entzian K 2011
Budeheim Bioserv dicopper phosphate IP38 tests report 2010: gentox mammalian cells
Dicopper hydroxide phosphate 38 12158-74-6 In vitro gene mutation in bacteria Entzian K 2011Budeheim Bioserv dicopper phosphate IP38 tests report 2010: gentox bacteria
Dicopper hydroxide phosphate 38 12158-74-6 Skin irritation in vivo Entzian K 2011Budeheim Bioserv dicopper phosphate IP38 tests report 2010: skin irritation
Dicopper hydroxide phosphate 38 12158-74-6 Acute eye irritation in vivo Entzian K 2011Budeheim Bioserv dicopper phosphate IP38 tests report 2010: eye irritation
Aluminium orthophosphate 40 7784-30-7 Skin irritation in vivo Giannini P 2008 skin irritation in vivo STPP 0 7758-29-4 Eye irritation Durando J 2011 Eye irritation in vivo
dicalcium phosphate (90%), plus 10% MCP 22 7757-93-9 Eye irritation Lowe C 2011 Eye irritation in vivo
dicalcium phosphate (97%), plus 3% MCP 22 7757-93-9 Eye irritation Durando J 2011 Eye irritation in vivo
Calcium acid pyrophosphate (66-79%), 16-24% MCP, 4-9% DCP, 1% TCP 25 14866-19-4 Eye irritation Durando J 2011 Eye irritation in vivo
Stabil 9 019 (Sodium aluminium phosphate 65% and monocalcium phosphate 35%) 43 7785-88-8 Eye irritation Lowe C 2011 Eye irritation in vivo
sodium aluminium phosphate (>90%) 43 7785-88-8 Eye irritation Durando J 2011 Eye irritation in vivo
Elemental phosphorus n/a n/a Reproductive toxicity Schardain JL 1985
One generation reproduction study in rats with elemental phosphorus (IR-82-215)
tetrasodium pyrophosphate (+9.1% STPP, 1.6% SAPP) 7 7722-88-5 eye irritiation Pooles A 2011
Blend B3 / pH 9.7: Rabbit enucleated eye
disodium dihydrogenpyrophosphate (+ 4.2% TSPP) 5 7758-16-9 eye irritiation Pooles A 2011
Blend A1 / pH 5.0: Rabbit enucleated eye
tetrasodium pyrophosphate (+8.4% SAPP) 7 7722-88-5 eye irritiation Pooles A 2011
Blend A2 / pH 9.0: Rabbit enucleated eye
tetrasodium pyrophosphate (+1.8% SAPP) 7 7722-88-5 eye irritiation Pooles A 2011
Blend A3 / pH 9.7: Rabbit enucleated eye
disodium dihydrogenpyrophosphate (+9.1% STPP, 3.8% TSPP) 5 7758-16-9 eye irritiation Pooles A 2011
Blend B1 / pH 5.5: Rabbit enucleated eye
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-25
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
tetrasodium pyrophosphate (+9.1% STPP, 7.6% SAPP) 7 7722-88-5 eye irritiation Pooles A 2011
Blend B2 / pH 9.0: Rabbit enucleated eye
tetrasodium pyrophosphate (+9.1% STPP, 1.6% SAPP) 7 7722-88-5 eye irritiation Pooles A 2011
Blend B3 / pH 9.7: Acute eye irritation in vivo
tetrasodium pyrophosphate (+1.8% SAPP) 7 7722-88-5 eye irritiation Pooles A 2011
Blend A3 / pH 9.7: Acute eye irritation in vivo
Glass H polyphosphate - IP8? 8 7785-84-4 eye irritation Barnett D and Nixon G 1972 Rabbit eye irritation
Glass H polyphosphate - IP8? 8 7785-84-4 dermal irritation Frank R, Nixon G 1972 dermal irritation
Glass H polyphosphate - IP8? 8 7785-84-4 Acute oral toxicity Whalen J and Klusman W 1972 Acute oral toxicity
trimetaphosphate - IP8? 8 7785-84-4 Repeated dose, oral Johnson GR 1973 Substance oral toxicity
tripotassium phosphate (50% aqueous solution) 14 7778-53-2 Skin irritation in vivo
Frank R and Nixon G 1976 skin irritation
Calcium dihydrogenpyrophosphate 25 14866-19-4 Skin corrosion - in vitro; screening Warren N 2011 Skin irritationdicalcium pyrophosphate 26 7790-76-3 Acute oral toxicity Nixon G 1966 Acute oral toxicitytrisodium hydrogen diphosphate 6 14691-80-6 Acute oral toxicity 2012 Acute oral toxicitytrisodium hydrogen diphosphate 6 14691-80-6 In vitro skin irritancy 2012 In vitro skin irritancytrisodium hydrogen diphosphate 6 14691-80-6 Ex-vivo BCOP 2012 BCOPtrisodium hydrogen diphosphate 6 14691-80-6 Acute eye irritation 2012 Acute eye irritationTrisodium trimetaphosphate 8 7785-84-4 Acute toxicity to fish 2012 Short-term toxicity to fish Trisodium trimetaphosphate 8 7785-84-4 Activated Sludge Respiration Inhibition 2012 ASRITrisodium trimetaphosphate 8 7785-84-4 Acute inhalation toxicity 2012 Acute inhalation toxicity tripotassium orthophosphate 14 7778-53-2 In vitro skin irritation 2012 In vitro skin irritationtrimagnesium bis(orthophosphate) 30 7757-87-1 In vitro skin irritation 2012 In vitro skin irritationtrimagnesium bis(orthophosphate) 30 7757-87-1 Ex-vivo BCOP 2012 BCOPtrimagnesium bis(orthophosphate) 30 7757-87-1 Acute eye irritation in rabbits 2012 Eye irritation
manganese bis(dihydrogen phosphate) 34 18718-07-5 Acute oral toxicity 2012 Acute oral toxicity
manganese bis(dihydrogen phosphate) 34 18718-07-5 in vitro skin corrosion 2012 in vitro skin corrosion
manganese bis(dihydrogen phosphate) 34 18718-07-5 in vitro skin irritancy 2012 in vitro skin irritancy
manganese bis(dihydrogen phosphate) 34 18718-07-5 Ex-vivo BCOP 2012 BCOP
manganese bis(dihydrogen phosphate) 34 18718-07-5 Acute eye irritation in rabbits 2012 Eye irritationmanganese hydrogen phosphate 35 51349-94-1 Acute oral toxicity 2012 Acute oral toxicitymanganese hydrogen phosphate 35 51349-94-1 in vitro skin corrosion 2012 in vitro skin corrosionmanganese hydrogen phosphate 35 51349-94-1 in vitro skin irritancy 2012 in vitro skin irritancymanganese hydrogen phosphate 35 51349-94-1 Ex-vivo BCOP 2012 BCOPmanganese hydrogen phosphate 35 51349-94-1 Acute eye irritation in rabbits 2012 Eye irritationDicopper hydroxide phosphate 38 12158-74-6 Acute inhalation toxicity 2012 Acute inhalation toxicity Aluminium orthophosphate 40 7784-30-7 Local Lymph Node Assay 2012 Skin sensitisation Sodium aluminium phosphate 43 7785-88-8 Acute oral toxicity 2012 Acute oral toxicitySodium aluminium phosphate 43 7785-88-8 In vitro skin irritation 2012 In vitro skin irritationSodium aluminium phosphate 43 7785-88-8 in vitro skin corrosivity 2012 in vitro skin corrosivity
aluminium dihydrogen triphosphate 41 13939-25-8 Acute oral toxicity 2012 Acute oral toxicity
aluminium dihydrogen triphosphate 41 13939-25-8 in vitro skin corrosion 2012 in vitro skin corrosive
aluminium dihydrogen triphosphate 41 13939-25-8 In vitro skin irritancy 2012 In vitro skin irritancy
Studies owned by the Consortium, by companies, or by other parties
IP Studies list - PART ** I ** Inorganic Phosphates (IP) Consortium - Company owned studies 16th April 2012 - page 2-26
substance sub ID CAS Nr. Endpoint AuthorsStudy
YearObject
aluminium dihydrogen triphosphate 41 13939-25-8 Ex-vivo eye irritancy 2012 BCOP
aluminium dihydrogen triphosphate 41 13939-25-8 Acute eye irritation 2012 Acute eye irritation
aluminium dihydrogen triphosphate 41 13939-25-8 Acute inhalation toxicity 2012 Acute inhalation toxicity
Studies owned by the Consortium, by companies, or by other parties