Subject index to volume 48 and 49

PROSTAGLANDINSLEUKOTRIENES I ANDESSENTIALFATTYACIDS I

Subject Index to Volume 48 and 49

The publishers would like to point out that Prostn- ,~lur~dins LmkotGerles and Essential Fatty Acids Volume

48 includes pages l-482; and Volume 49 includes pages 4X3-992. From 1994 each volume will commence with

page 1.

A

.Acet) Ichohne effect of rndothelium removal on basal and muscarinic cholinergic

stimulated rat mesenteric vascular bed prostanoid synthecis. 37.1

pharmacological model for airway hypersensitivity produced by propranolol and reserpine in guinea-pigs. 447

.Adenylate cyclase bimodal regulation of adenylate cyclase by prostaglandin E, recrp-

tar< in porcine ciliary epithelium, 765 cancer cachexia: interaction between eicosapentaenoic acid and

inhibitory guanine nucleotide-regulatory protein, 10.5 modulatmn by \ex hormones of the membranous transducing system

regulating fatty acid mobilization in adipose tissue. 91 protein hinaae A activator\ inhibit agonist induced prostaglandin

production in human amnion. 355 .Adipose tibuue

cancer cnchexia: interaction between eicosapentaenoic acid and inhibitory guanine nucleotide-regulatory protein. I05

modulation by wx hormone\ of the membranous transducing system regulating fatty acid mobilization in adipose tissue. 91

regulation of gene expression by fatty acids in the adipose cell. X9 Adrenal gland(s): fatty acids may regulate aldosterone secretion and

mediate wme of insulin’s effect? on blood pressure. 43 A:e: sodium loading and renal prostaglandins in old rats. X I5 .-\ II% “4

Sects 01 qsteinyl leukotriene antagonist ONO-1078 on antigen- mduced re\pones in allergic sheep. ?.?.?

zffcct\ ut new leukotriene receptor antagonist ONO-107X on human bronchial smooth muscle in vitro. 241

-ffect< ot novcl thromboxane A, receptor antagonist S-1-152 on antigen-induced bronchoconstriction and airway hyperrespon- Gvene\\ in guinea-pig. 31.3

Imp”rtance of wcondary thromboxane A, release in mediating cndothelin- I -induced bronchoconstriction and vasopressin in the guinea-pip. 261

pharmacological model for airway hypersensitivity produced hy prop!-anolol and reserpine m guinea-pigs. 347

role of leukotrienes and platelet-activating factor in allergic hi-onchocon\triction and their interactions in guinea-pig airway in \ ~vo. 576

Ajoene: cftcct\ of a garlic-derived principle on aggregation and arachldomc acid metabolism in human blood platelet\. 5X7

Alcohol effect of chronic ethanol consumption on the spontaneous contrac-

tions prostaglandin production triglycerides and glucose metabolism of uterine strips isolated from pregnant rats and in embryos, 495

Type A behaviour and alcohol consumption: effects on resting and post-exercise bleeding time thromboxanc and prostacyclin metabolites. 14.3

Aldosterone: fatty acids may regulate aldosterone wcretion and mediate some of insulin’s effect5 on hlood prewwe. 13

Allergic reactions effects of cysteinyl leukotriene anta_ponixt ONO- 107X on antipen-

induced responses in allergic sheep. 233 effects of new leukotriene receptor antagonl\t ONO-107X on human

bronchial smooth muscle in vitro. 2-11 effects of novel thromboxane -4, receptor antagomst S-l-IS2 on

antigen-induced bronchoconstriction and airway hypcrreapon- siveness in guinea-p&. 343

pharmacological model for airway hyper\ensni\lt) produced b! propranolol and reserpine in guinea-piss. 447

purification of human blood basophils and leuhotriene C, gcnemtion following calcium ionophore stimulation, 7X3

role of eicosanoids in the pathogenesis of atoptc drnnatitls. -109 role of leukotrienes and platelet-activating factor in allergic

bronchoconstriction and their interaction in guinea-pig airwq in viva. 579

Alpha-linolenic acid: function of dietary polqun~tul-ated fatty acids m the nervous cywm. 5

Alveolar macrophapeh: comparison of hepaw ?plenic pcritoncnl and alveolar macrophages with respect IO prostylandin E> thromboxane B2 production and antibotly-dependenl ccllul& cytotoxicity function. 1-t’)

Amnion action\ of interleukin-2 on amnion prostaglandm hio\ynthe\is. WY epidennal growth factor and transformmg growth factor-tx enhance

the interleuhin-l- and tumour nccro\is factor-\tilnulrtted prostnglandin E, production and the IL-l \ptxcific bindms on amnion cells. Y23

protein hinaae A actwatorh inhibit agoniht induced pro\tqlandin production in human amnion. 3.55

Angina pectoria therap): pilot trial to drterminc the etficac~ of low dose fish oil in geriatric patlentc. 6X7

Angiotensin converting enzyme (ACE, ACE activity in cultured porcine puhnonnr! artery cndothelial cells

treated with paraquat, 291 comparison of the potency or variou\ serotype\ of E.col~ lipo-

polyaaccharides 111 htimulatinp proataglandin 1, productwn and suppressmg ACE activit) in cultured humarl umbdical vein rndothelial cells. 955

Antibody-dependent cellular cytotoxicity: compnriwn of hepatlc \plenic peritoneal and alveolar macl-ophafra. 14Y

.4ntiphohpholipid antibodich: the lupw anticoagulant and eico\anoid\. 1x3

975

976 Prostaglandins Leukotrienes and Essential Fatty Acids

Apoptosis induction in blood cells from a patient with chronic myelogenous leukaemia by selective S-lipoxygenase inhibitor SC41661A. 323

Arachidonic acid (AA ) antiplatelet components isolated from oil of cloves and. 363 AA and cell signalling in the ovary and placenta. 79 AA inhibits electrically-induced intracellular calcium transients in

neonatal rat cardiomyocytes. 837 AA release and inositol lipid metabolism in response to bradykinin

and related peptides in human endometrial cells in vitro. 253 AA supplementation dose-dependently reverses the effects of a

butter-enriched diet in rats, 247 distribution of unsaturated fatty acids in phospholipids of arteries

from nonpregnant pregnant and fetal sheep, 907 effect of ascorbate on essential fatty acid composition in B16

melanoma cells. 77 1 effect of chronic ethanol consumption on the spontaneous con-

tractions prostaglandin production triglycerides and glucose metabolism of uterine strips isolated from pregnant rats and in embryos, 495

effects of garlic-derived principle ajoene on aggregation and AA metabolism in human blood platelets, 587

effects of interleukin-lor on AA metabolism in human osteosarcoma osteoblastic cells. 52 1

fatty acids as antiinflammatory and immunomodulatory agents, 57 hyperoxia decreases cyclooxygenase activity in endothelial cells.

455 increased thromboxane A? production at primary tumour site in

metastasizing squamous cell carcinoma of the larynx, 527 interactions between arachidonic and eicosapentaenoic acids during

their dioxygenase-dependent peroxidation. 23 and interleukin-6 release from rat peritoneal macrophages in vitro:

evidence for a prostacyclin-dependent mechanism, 915 isolation identification and synthesis of an endogenous arachidonic

amide that inhibits calcium channel antagonist 1.4.dihydro- pyridine binding. 429

modulation of lipid derived mediators by polyunsaturated fatty acids, 5 I

oxy-radicals lipid peroxides and essential fatty acids in patients with glomerular disorders. 603

prostacyclin release in experimental diabetes: effects of evening primrose oil. 699

prostaglandin biosynthesis in the microcirculation: regulation by endothelial and non-endothelial factors. 723

prostaglandin F?, synthesis in the hippocampal mossy fibre synaptosomal preparation and. 127

regulation of gene expression by fatty acids in the adipose cell. 89 relationship between factors influencing Na+-K+-ATPase activity

and eicosanoid production from “C-AA in spayed rat uteri. 273 renal infusion of. effect on water excretion of. 297 role of fatty acids

in signal transduction: modulators and messengers. 117 Ascorbate. effect on essential fatty acid composition in B 16 melanoma

cells of. 77 1 Aspirin

effect of policosanol on cerebral ischaemia in Mongolian gerbils: role of prostacyclin and thromboxane A:, 695

platelet-activating factor-induced death in NMRI mice and. 265 regular and enteric-coated, effects on bleeding time thromboxane and prostacyclin of. 5 IS

Asthma effects of cysteinyl leukotriene antagonist ONO-1078 on antigen-

induced responses in allergic sheep. 233 effects of new leukotriene receptor antagonist ONO-1078 on human

bronchial smooth muscle in vitro, 241 effects of novel thromboxane AI receptor antagonist S-1452 on

antigen-induced bronchoconstriction and airway hyperrespon- siveness in guinea-pigs, 343

pharmacological model for airway hypersensitivity produced by propranolol and reserpine in guinea-pigs. 447

role of leukotrienes and platelet-activating factor in allergic bronchoconstriction and their interactions in guinea-pig airway in vivo. 579

Atherosclerosis eicosapentaenoic acid and. 337 eicosapentaenoic acid abolishes the proatherogenic effects of

cholesterol: effects on migration of bovine smooth muscle and endothelial cells in vitro. 463

prostaglandin biosynthesis in the microcirculation: regulation by endothelial and non-endothelial factors, 723

putative role of dietary omega-3 polyunsaturated fatty acids in oxidative modification of low density lipoprotein. 397

Atlantic salmon (S&W S&V). sunflower linseed and fish oils affect phospholipid fatty acid composition development of cardiac lesions phospholipase activity and eicosanoid production in. 665

Atopic dermatitis. role of eicosanoids in pathogenesis of, 409

B

Basophils: purification from human blood and leukotriene C, generation following calcium ionophore stimulation. 783

Benzo(a)pyrene. effect on prostaglandin E2 receptor expression in hamster buccal uouch of. 82 1

Blastocysts. mouse, infiuence of indomethacin on hatching of. 683 Blood cells: role of leukotrienes in the regulation of proliferation of

normal and leukaemic haemopoietic cells. 123 Blood pressure

comparative study of diets enriched with evening primrose blackcurrant borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats. 809

epidural blood flow during prostaglandin E,- or trimethaphan- induced hypotension. 873

fatty acids may regulate aldosterone secretion and mediate some of insulin’s effects on blood pressure. 43

U 46619 induces different blood pressure effects in male and female spontaneously hypertensive rats, 469

Bone effects of glucocorticoid on signalling by prostaglandin E2 in

osteoblast-like cells. 867 effects of interleukin-lee on arachidonic acid metabolism in human

osteosarcoma osteoblastic cells, 521 modulation of prostaglandin El-induced Ca” influx by steroid

hormones in osteoblast-like cells. 7 11 Book review: Polyunsaturated Fatty Acids in Human Nutrition, 101 Bradykinin: arachdonic acid release and inositol lipid metabolism in

response to bradykinin and related peptides in human endometrial cells in vitro. 253

Brain effect of nordihydroguaiaretic acid on leukotriene C, and pro-

staglandin EI production following different reperfusion periods in rat brain after forebrain ischaemia correlated with morphological changes. 633

effect of policosanol on cerebral ischaemia in Mongolian gerbils: role of prostacyclin and thromboxane A?, 695

function of dietary polyunsaturated fatty acids in the nervous system. 5

isolation identification and synthesis of an endogenous arachidonic amide that inhibits calcium channel antagonist I .4_dihydro- pyridine binding, 429

prostaglandin D2 and endothelin-1 induce prostanoid production in capillary endothelium of human brain, 789

prostaglandin F,, synthesis in the hippocampal mossy fibre synaptosomal preparation. 127. 877

thromboxane receptor antagonism and aynthase inhlbition in cerebral ischaemia. 7 1 I

Breast amplification of signals from growth factor receptors by fatty acids

in mammary epithelial cells. 71 cancer of

plant and marine n-3 fatty acids inhibit experimental metastasis of rat mammary adenocarcinoma cells, 309

role of free fatty acids in regulating the t&us availability and synthesis of sex steroids, 1 I I

pain. effects of gamma-linolenic acid on. 101 Bronchoconstriction srr III&I. Airway

C

Cachexia. cancer: interaction between eicosapentaenoic acid and inhibitory guanine nucleotide-regulatory protein. 105

Calcium arachidonic acid inhibits electrically-induced intracellular calcium

transients in neonatal rat cardiomyocytes. 837

calcium homeohtasis and ricosanoid formation in human platelets.

277

rndogenous prostaglandin E, modulates calcium-induced differentiation in human skin keratinocytes. 777

Isolation Identification and synthesis of an endogenous arachidonic amide that inhibits calcium channel antagonist I .4-dihydro-

pyridine binding. 320 modulation of prostaglandin E,-induced Ca” influx by steroid

hormones m os~eoblast-like cells, 7 I 1

po\\ible cross-refractorme\s between phoapholipase AI and the

calcium ianophore AZ.3 1X7 in the stimulation of uterine

proctaplandm production. 327

pro\taglandin F Jr, synthew in the hippocampal mossy fibre syn-

aptnsomal preparation and. 127, 877

purification of human blood basophila and leukotriene C, generation

Illowin~ calcium ionophore stimulation. 783

Cancer w(a Iumour\ Cardiovascular di\eaae .YCC Heart disease

c’c111\1 ,Impllfication of Ggnals from growth factor receptor, by fatty acids

in mammary epithelial cells. 7 I :ytoplasmlc fatty acid binding protein: significance for intracellular

transport ot fatty acids and putative role on signal transduction pathways. i.:

_+l’cc~ of I6.16.dlmethyl pro\taglandin E, on proliferation of an

tnte\tinal goblet cell line and its synthesis and secretion of

mucin $ycoproteinb. 423 -ndogenous proctaglandin E2 modulates calcium-induced differen-

tiation in human \kin keratinocyte\. 777 Ihtty acids as antiinflammatory and immunomodulatory agent>. 57

tree fatty acid\ ;I< modulators of the ateroid hormone message. 63

Induction of apoptoqis in blood cell\ from a patient with chronic

myclogenou~ Irukaemia by wlrctive S-lipoxygenase inhibitor

SCJ166lA. 3’3

modulation of lipw.1 derived mediators by polyunsaturated fatty acid\. 51 rtrw~ural and functional ahpecth of cytosohc fatty

.tcld-hindins proteins. XX7 wr u/.v~ Membranet\~: Signal transduction

Cholesterol

-t’fect or prava\tatm on fatty acid profile of low density lipoprotein

tn patlent\ with hypercholesterolaemia. 155 -ic~)\apcntsenol~ acid abolisheh the proatherogenic effects of

chcrlwterol: effect\ on migration of bovine smooth muscle and

cndothclial cell\ in vitro. 463

.wning primrose 011 and fi\h oil in non-msulin-dependent diabete\. MU

:ipoprotrln\ tram normolipidaemic and dyslipidaemic subjects

modify the thromboxane A, c generation by platelet\ in clotting

human blood. 175 Chromosome\: enhancement of antineoplastic effect and attenuation

01 \I\ICI- chromatid exchanges by prostaglandin ET in Ehrlich

ascitc\ tumour cells treated with cyclophosphamide ;n viva. 707

Gil-rhosi\: pmstaglandin and portal hypertension. 203 ClLwe\: antlplatelcr components Isolated from oil of cloveh. 363

Compltwcnr 5~ induce\ in vi\” \)nthesl\ of cyhteinyl leukotriene\ in rat\. 3.3 I

Cr-jhn’r tliwaw: leukotriene B, o-hydrolase activity in polymorphonuclear Icuhoqtes from patient\ with intlammatory bowel

diware. 1x0

(‘4 tol\me\

ictmns 01’ interlwhin-2 on amnion prostaglandin biosynthesis, YSY

uwhidonlc acid ctimulate\ interleukin-6 release from rat peritoneal

macrophagc\ in vitro: evidence for a prostacyclin-dependent mechanism. Y I5

,:ffect\ ol intcrleuhu-lo! on arachidonic acid metabolism in human o\tcowwma o\teoblastic cell\, 521

,:pidermal crow t h factor and tmnsforming growth factor-a enhance

the lnterlcuhin-l- and tumour necrosis factor-stimulated

prtr\ia~landm E, production and the IL-I specific binding on amnwn cell\. 923

‘Hn> acid\ a\ antiinflammatory and immunomodulatory agenta. 57 nhibirmli of the thermogenic and pyrogenic response\ to

tntcl leuhn-P in the rat by dietary n-3 fatty acids. 6 I5 ntel-leukiw I I), \timulatea prostqlandin E2 and F,,, synthesis in

humw warian granulosa cells in culture. 963 modulnrlcw of lipid derived mediatol~\ by polyunsaturated fatty

:Icid\. 5 I

mononuclear cell-conditioned medtum cnhancch thrombin-stl-

mulated prostaglandin 1, production b! human umbilical vein

endothelial cells in culture. 675 prostaglandin El antagonizes singival fibrobla\t proliferation

stimulated by interleukin- I p. 847 Cytoplahmic fatty acid binding protein: significance for intracellular

transport of fatty acids and putative role on hi@ tmnduction

pathways. 33

D ---v

!

I I-Dehydrothromboxane B, excretion. effect ot anchovy 011 \upple-

mentation on. 305

Delta-h-desaturase: function of dietar! polyun\aturated fart! acid\ 111

the nervous system. 5

Dermatitis. atopic. role of eicosanoida in the pathogenew of. .NlY

Developing countries: lipid intahe during prepnancy and possible effect of essenlial fatty acid deficient! on fetal Frowth. I3Oz

Diabetes mellitus

evening primrose oil and fish oi I m non-in~~lll~~-drpe~~dc~~t disbete\.

569

neuropath! of, effects of gamma-lmolenic acid on. IO I prostacyclm release in experimental diahew: effect\ of cbcning

primrose oil. 6YY pro\ta$mdin biosynthesis in the IiiicrocIrcul;ltioII: regulation b!

endothelial and non-endothelial factor\. 73 treatment of patients with peripheral arterial occlusive discaw wnh

intravenous iloprost and prostaplandin 15, 577 Diclofenac sodium

identification of two different rate-hmitmg mechamama controlling

the release of KSAIDs from Glastic pol>merlc device\. 391 protective eftect afaIn\ endotoxic \h(lch in anac\thctlLed pq\ ol’.

i ‘U DietfaTy)

antiplatelet components isolated from 011 ot ckne\. 36.3

aqueous extract\ of garlic inhibit pro\tagiandin \!nthc\~\ in the

ovine ureter. X5.5

arachidomc acid wpplementation do\~-il~pendcntl~ reverw the

effect\ of a butter-enriched diet in rat\. 747

compsmtive \tudq ot‘ diets enriched u ith evening primrow blach-

currw~ borage or fungal oils on blood pres\ure and pre\sol

re\ponhes *n \pontnneousl! h)pcrten\i\? rat\. X09 effects of a fish oil rich diet on hypero\ic lung damage in mice. 969

efl’ecr\ of fish 011s on lipid variable\ and pintclct I‘unctior indice&. 6-15

effect\ of garlic-derived principle qoenc <III aggrqatlon and arachidonic acid metabolism m human blood platelets. 5X7

effect\ of starvation on the urinary content\ ot primary thromboxane and pro\tac?clin metabolne\ 311d ., po\\ible \rlcnium- dependent role for ptwtacyclin rn the r~w1 handlmg of hetone bodie\. 385

indomethacin-lnduccd gastromtcstinal uIwI\ 111 Irat\: cllcct\ ot

dIetar\ fattv acid\ and endolosln. 23 ingestion (if m&in, oil reduce, intravascular pr~~duc~~on ot thrombo-

wie ,A, ;I\ meawred b! I I -deh~drorhI-ombo\\ane B- cwretion. 305

inhihitmn 01 the thermogemc .md p\ rogenlc reaponws to intcrleuhin-0 in the lmt by dietar! n-3 fan> ;~cid\. h Ii

interaction bet\veen \ itamin Bh deficlenc! and low EFA dietq

intahe on hidne! phospholipids and prortaglandin E, in the t-at. 5.: I

lipid intake duriq pregnanq in de\ elopmf counts-les: po\Gble effect of r\\entlal fatty acid deflclrnc\ on fetal growth. IX)

modulation of lipid derived mediator-5 b! po1\ un\a~ul.;ned fan\ Xid\. 5 I

978 Prostaalandins Leukotrienes and Essential Fattv Acids


putative role of dietary omega-3 polyunsaturated fatty acids in oxidative modification of low density lipoprotein, 397

sunflower linseed and fish oils affect phospholipid fatty acid composition development of cardiac lesions phospholipase activity and eicosanoid production in Atlantic salmon, 665

supplementation with primrose oil or fish oil does not change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women. 691

Diethylnitrosamine, effect on prostaglandin E and lipid peroxidation levels in rat liver lung and renal tissue of. 805

Dihomo-gamma-linolenic acid (DGLA) effect of ascorbate on essential fatty acid composition in B16

melanoma cells, 77 1 evening primrose oil and fish oil in non-insulin-dependent diabetes,

569 fatty acids as antiinflammatory and immunomodulatory agents, 57

Dihydroxyvitamin D,: modulatlon of prostaglandin Ez-induced Ca” influx by steroid hormones in osteoblast-like cells, 7 11

DNA synthesis induction of apoptosis in blood cells from a patient with chronic

myelogenous leukaemia by selective 5-lipoxygenase inhibitor SC4166lA. 323

prostaglandin Ez antagonizes gingival fibroblast proliferation stimulated by interleukin- 10, 847

Docosahexaenoic acid (DHA) inhibitory effect of DHA-containing phospholipids on 5-lipo-

xygenase in rat basophilic leukaemia cells, 861 modulation of lipid derived mediators by polyunsaturated fatty

acids, 5 1

E

Eicosapentaenoic acid (EPA) and atherosclerosis. 337 cancer cachexia: interaction between eicosapentaenoic acid and

inhibitory guanine nucleotide-regulatory protein. 105 EPA abolishes the proatherogenic effects of cholesterol: effects

on migration of bovine smooth muscle and endothelial cells in vitro, 463

evening primrose oil and fish oil in non-insulin-dependent diabetes. 569

interactions between arachidonic and eicosapentaenoic acids during their dioxygenase-dependent peroxidation. 23

oxy-radicals lipid peroxides and essential fatty acids in patients with glomerular disorders, 603

pilot trial to determine the efficacy of low dose fish oil in the treatment of angina pectoris in geriatrics, 687

Endometrium arachidonic acid release and inositol lipid metabolism in response to

bradykinin and related peptides in human endometrial cells in vitro. 253

effects of guinea-pig endometrial proteins on phospholipase A2 activity and prostaglandin synthesis, 219

synthesis of 12hydroxyeicosatetraenoic acid by human endometrium and decidua. 609

Endothelin-1 endothelin- I -induced bronchoconstriction and vasopressin in the

guinea-pig is mediated by secondary thromboxane AZ release. 761

prostaglandin D2 and endothelin-1 induce prostanoid production in capillary endothelium of human brain. 789

Endothelium comparison of the potency of various serotypes of E. co/i lipo-

polysaccharides in stimulating prostaglandin I2 production and suppressing ACE activity in cultured human umbilical vein endothelial cells, 955

effect of removal on basal and muscarinic cholinergic stimulated rat mesenteric vascular bed prostanoid synthesis, 373

eicosapentaenoic acid abolishes the proatherogenic effects of cholesterol: effects on migration of bovine smooth muscle and endothelial cells in vitro. 463

hyperoxia decreases cyclooxygenase activity in endothelial cells. 455 mononuclear cell-conditioned medium enhances thrombin-

stimulated prostaglandin I2 production by human umbilical vein endothelial cells in culture. 675

prostaglandin biosynthesis in the microcirculation: regulation by endothelial and non-endothelial factors, 723

prostaglandin D? and endothelin- 1 induce prostanoid production in capillary endothelium of human brain, 789

prostaglandin I? production and angiotensin converting enzyme activity in cultured porcine pulmonary artery endothelial cells treated with paraquat, 291

Endotoxin(s) comparison of the potency of various serotypes of E. co/i lipo-

polysaccharides in stimulating prostaglandin I? production and suppressing ACE activity in cultured human umbilical vein endothelial cells, 955

endotoxic shock has differential effects on renal and splanchnic eicosanoid synthesis, 509

indomethacin-induced gastrointestinal ulcers in rats: effects of dietary fatty acids and endotoxin, 229

macrophage prostaglandin Ez and oxidative responses to endotoxin during immunosuppression associated with anaesthesia and transfusion, 945

mononuclear cell-conditioned medium enhances thrombin- stimulated prostaglandin IZ production by human umbilical vein endothelial cells in culture, 675

protective effect of diclofenac sodium against endotoxic shock in anaesthetized pigs. 193

Epidennal growth factor amplification of signals from growth factor receptors by fatty acids

in mammary epithelial cells. 7 1 epidermal growth factor and transforming growth factor-a enhance

the interleukin- I- and tumour necrosis factor-stimulated prostaglandin Ez production and the IL-l specific binding on amnion cells, 923

protein kinase A activators inhibit agonist induced prostaglandin production in human amnion, 355

Erythrocyte deformability. in vitro effect of triacylglycerols on. 35 1 Eugenol and acetyl eugenol: antiplatelet components isolated from oil

of cloves. 363 Evening primrose oil

comparative study of diets enriched with evening primrose blackcurrant borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats. 809

in experimental diabetes. 699 in non-insulin-dependent diabetes mellitus. 569 in pre-eclamptic women. 69 1

Excretion complement 5a induces in vivo synthesis of cysteinyl leukotrienes

in rats. 33 1 effect of leukotrienes on renal water excretion, 297 effects of starvation on the urinary contents of primary thromboxane

and prostacyclin metabolites and a possible selenium- dependent role for prostacyclin in the renal handling of ketone bodies. 385

ingestion of marine oil reduces intravascular production of thromboxane A2 as measured by 1 I-dehydrothromboxane B, excretion. 305

leukotriene B, generation by blood polymorphonuclear leukocytes after incubation in urine. 761

sodium loading and renal prostaglandins in old rats. 8 15 supplementation with primrose oil or fish oil does not change

urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women. 69 I

Eye(s): bimodal regulation of adenylate cyclase by prostaglandin E, receptors in porcine ciliary epithelium. 765

F 1

Fat SW Adipose tissue Fatty acids

amplification of signals from growth factor receptors by fatty acids in mammary epithelial cells. 7 1

arachidonic acid and cell signalling in the ovary and placenta. 79 arachidonic acid supplementation dose-dependently reverses the

effects of a butter-enriched diet in rats. 247 and celi signalling. 1 cytoplasmic fatty acid binding protein: significance for intracellular

transport of fatty acids and putative role on signal transduction pathways, 33

dietary sunflower linseed and fish oils affect phospholipid fatty acid

Subject Index Y7Y

composition development of cardiac lesions phosphofipase

activl~y and eicosanoid production in Atlantic salmon. 665

distribution of unsaturated fatty acids in phosphofipids of arterie from nonpregnant pregnant and fetal sheep. 907

dynamics of the membrane lipid phase. 27

cfi’ect of a\corbate on essential fatty acid composition in B16

melanoma cell\. 77 I tffect of pravastatin on fatty acid profile of low density lipoprotein

m pattents with hypercholesterofaemia. 155

ct’fect of tl-iacylplycerofs on erythrocyte deformability in vitro. 35 I

tffecth ot fi\h oil\ on lipid variables and platelet function indicra. 645

effect\ ot +imma-finolenic acid on breast pain and diabetic neuropathy: possible non-eicosanoid mechanisms. IO1

tatty acid\ as antiinflammatory and immunomodulatory agents. 57 fatty acid\ may regulate afdosterone secretion and mediate some of

insulin’s effecti; on blood prehwre. 43

tree fatty acid\ a\ modulators of the steroid hormone message. 63

tunctlon tlf dietar) polyunsaturated fatty acids in the nervow

\y\tem. 5

Indomethucin-induced gastrointestinal ulcers in rats: effects of

dietary tatt! acid5 and endotoxin. 129

inhibitor) effect of doco\ahexaenoic acid-containing phospholipids

on 5-iipoxygenase in rat basophific leufiaemia celfa. 861

Interaction between arachidonic and eicosapentaenoic acids during their diouygenase-dependent peroxidation. 23

iilterdctiw hetwcen vitamin B6 deficiency and low ehsentiaf fatty acid dietar) Intake on kidney phospholipids and prostaplandin

El in ihc ml. 53 I rnechnniw~ of flpid mobililatlon associated with cancer cachexia:

interaction between eicosapentaenoic acid and inhibitory ;uamnc nucleotidr-rrgul3torv protem. I05

migaine and. 5.37

~w~tlufatiw ot 1q11d derived mediator\ by polyunsaturated i’atty

3Cld\. 5 I rlodulation by sex hormones of the membranous transducmg system

regulating tatty acid mobdtration in adipose tissue. Yl c*\y-radicals lIpid peroxide\ and e\\entiaf fatty acids in patients with

glomrrufar clirorders. 603 phykwhemlcal approach of the tunction of the fatty acid incor-

poratlon in hiologcal membranea. I7 lrqufatwn oi gene elpreskn by fatty acids in the adipose cell. X9

role of ~‘~IIJ acid\ in \iyuf transduction: modulatora and messenger\, I I7

role 01 trcr fatty ac~l\ in reyufatmg the tissue availability and \! nthc\i\ 01 kc‘\ steroid\. I I I

\hol-t cham fatt\ acitf-induced hqperventifation i\ due to pro\tnefandln.F,,,. 833

wwtuml and tunctionaf aspect\ of cytosolic fatty acid-binding protcmk XX7

ciwlbutlon of unsaturated tatty acids in phoapholipids of arterich fl-om nonpregnant pregant and fetal sheep. 907

1.~~1 mtahe dut-lny pregnancv in developing countries: possible rl’fcct of r\wntial fatt) a&i deficiency on fetal Frowth. I39

f-c\er: lnhihltinn 01 the thrrmogenic and pyrogenic reapon\es to inter-leuhin- I p tn the rat by dietary n-3 fatty acids. 615

F;lhroblu\t\. singI\ al: pro%qfandin E> inhibition of proliferation \timlll,ttcd h! Interleuhin-I p. X47

f,l\ll 011

c!irtar.!. tl\h 011 supplementation alters LTB, : LTB, ratios but dot\

noI ;(I lcct tht‘ esf,resw~n of acute praft versus host diwase in Illli’c‘. 56 I

dletar! wItlower Im\eed and fish oila affect phospholipid fatty acid

c~mpwtion development of cardiac lesion5 phoaphofipa\e

acti\ II~ and elcosanoid production in Atlantic salmon, 665

clietar! \(117f7lenlc11tation filth prnnro\e oil or fish oil doe\ not

chanpe urinary excretion of prostacycfm and thrombosane

metahtrlite\ m pl-e-ecfamptic women. 691

cl’fect\ of ;I fish oil rich diet on hyperoxic lung damage in mice. 96Y c‘ltect\ ot fi\h OII\ on lipid vwiable\ and platelet i’unctlon indices.

h45

cbeninf f~! imrow 011 and f~\h oil in non-msufin-dependent dlabetrh. MY

ingestion of marine 011 reduces intravascular production of thrombo-

xane A, as measured by I I-dehydrothromboullne B1 ewretion.

305 pilot trial to determine the efficacy of lowdose fi\h oil m the

treatment of angina pectoris m gerialrick 687 plant and marine n-3 fatty acid5 inhibit euprrimentnl meta\ta\is of

rat mammary adenocarcinoma cell\. 300

Free radicals

anti-mutagenic action of prostacqclin and. 175 effect of diethylnitrosamine on prostaglandin E and lipid peroxida-

tion levels in r3t.T liver lung and renal tlww. X05 effects of a fi\h oil rich diet on hypenwic lung damqe m mice.

96Y macropha~e prostaglandin E> and oxidati\e reaponsrs to endotoxm

during immunowppresiion associated I\ tth anacsthesta and

transfusion. 945

oxy-radicals fipld peroxides and essential Cart) acid\ in patlent\ with

plomrrular disorders. 603

peptidoleuhotriene\ increahe the eftlux of :lutathione from perfused rat liver. 7 I5

proatacyclin regulate\ splanchmc blood l’lo\\ clurm:l carI! haemorrhage/reperfusion injury. 10 I

putative role of dietary omega-3 pol~un\atura~ed l’atty ,wids 111

o~ldattve modification of low densIt! fifwproteitl. 397

(; -------1

Gamma-linolenic acid IGLAJ

comparative study ot diets enriched ~sith c‘\ wing primrow hlach-

currant bomge or fungal oifz on blood preww ancf pre\w

rr\ponhes in spontaneou4y h! pertew\c rat\. SOY

effect of a\corbate on ersentiaf fan! acid i,ompo\ition in RI6

melanoma cell\. 77 I

effect\ ot GLA on brcaqt pam and diabctlc neuropath! : fw\\ible

noll-eico\anoid mechanism\. IO I

fatty acids a\ antiintlammatorv and ilnmunc~niodulntor~ agent\. 57 plant and marine n-3 l’atty acid5 inhibit exprrlmental metnsta\l< of

rat mammary adenocarcinulll~l cell>. 3 IN Garlic

effect\ of :tjoene on ugregation and arachidonic acid mrt&~f ~\m m human blood platelet\. 5X7

Gastrointe\tin,lf tract

effect\ ot. regufx and enteric-coated a\p~r~n ,111 blcedmg time

thromboxane and pro\tacyclm. 5 IS indomethacin-illiiuc~~l gastrointestinal ulcer\ 111 Iat\: i‘l kit\ ot

dietq tatty acid\ and rndotoxin. 27’)

fcuhotrwx B, w-hydrolaw aclivity 111 pof! morphonuclear Icuh+

cl le\ iron, patient\ with inffammalory bowel diwaw. 4X0 SC-46275: 3 potent and highly wlectl\e :~gon~\;t at the EP.3 rcccptor.

Y)iY

pro\tacycIm a\ a potent antl-mutafcn. I75 repulation of gene rxpressmn by l’att! acldb 111 tht‘ atfipose cell. XY

Genistein: effect\ on platelet function 3Ic due III thrombosane receptor

antqnniam rathcl- than inhihitlon ot‘ wo\me i\~naw. ?7Y

Gfucocortlcoid. effects on \i~nalling b! pro~&landm El in o\teobla\t- fihe cells of. X67

Gfutathlone cl‘tlu\ from prrfuwd 1’;u lilt’r. cttcct 01 leuhotricn~-\ on. 71.5


Growth factors amplification of signals from growth factor receptors by fatty acids

in mammary epithelial cells. 7 1 protein kinase A activators inhibit agonist induced prostaglandin

production in human amnion. 355

H

Haemopoiesis: role of leukotrienes in the regulation of proliferation of normal and leukaemic haemopoietic cells. 123

Haemorrhage exaggerated splanchnic prostaglandin I2 release following acute

haemorrhage is due to new protein synthesis, 307 prostacyclin regulates splanchnic blood flow during early

haemorrhage/reperfusion injury. 401 Heart (disease)

arachidonic acid inhibits electrically-induced intracellular calcium transients in neonatal rat cardiomyocytes. 837

dietary sunflower linseed and fish oils affect phospholipid fatty acid composition development of cardiac lesions phospholipase activity and eicosanoid production in Atlantic salmon. 665

effect of pravastatin on fatty acid profile of low density lipoprotein in patients with hypercholesterolaemia. 155

effect of prostaglandin E, on renal function after cardiac surgery involving cardiopulmonary bypass. 627

pharmacokinetics and pharmacodynamics of the prostacyclin analogue 15AU8 1 in the anaesthetized beagle dog. 159

pilot trial to determine the efficacy of low-dose fish oil in the treatment of angina pectoris in geriatrics. 687

radioimmunoassay for the prostacyclin analogue 15AU81: a preliminary pharmacokinetics study in the dog, 167

Type A behaviour and alcohol consumption: effects on resting and post-exercise bleeding time thromboxane and prostacyclin metabolites. 143

Hippocampal mossy fiber synaptosomal preparation, prostaglandin F1, synthesis in. 127, 877

Histamine, gastric mucosal: in relation to portal somatostatin following small bowel resection in guinea-pigs. 3 19

Hormones amplification of signals from growth factor receptors by fatty acidr

in mammary epithelial cells. 7 1 arachidonic acid and cell signalling in the ovary and placenta. 79 changes in gastric mucosal histamine and prostaglandin E,-like

activities in relation to portal somatostatin following small bowel resection in guinea-pigs. 3 19

changes in phospholipase A, activity of the rabbit ampullary epithelium by ovarian steroids, 315

effects of guinea-pig endometrial proteins on phospholipase Al activity and prostaglandin synthesis. 219

fatty acids may regulate aldosterone secretion and mediate some of insulin’s effects on blood pressure, 43

free fatty acids as modulators of the steroid hormone message. 63 modulation of prostaglandin El-induced Ca’+ influx by steroid

hormones in osteoblast-like cells, 71 1 modulation by sex hormones of the membranous transducing system

regulating fatty acid mobilization in adipose tissue, 91 role of free fatty acids in regulating the tissue availability and

synthesis of sex steroids, 11 1 12-Hydroxyeicosatetraenoic acid synthesis by human endometrium

and decidua, 609 Hypercholesterolaemia see [rr&r Cholesterol

Hyperoxia effect on cyclooxygenase activity in endothelial cells of. 455 effects of a fish oil rich diet on hyperoxic lung damage in mice.

969 Hypertension

comparative study of diets enriched with evening primrose blackcurrant borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats, 809

effect of 5-lipoxygenase and cyclooxygenase blockade on porcine haemodynamics during continuous infusion of platelet- activating factor, 549

fatty acids may regulate aldosterone secretion and mediate some of insulin’s effects on blood pressure. 43

prostaglandins and portal hypertension. 203 U 466 19 induces different blood pressure effects in male and female

spontaneously hypertensive rats. 469

Hyperventilation induced by short chain fatty acids is due to prostaglandin FZu. 833

I I

Iloprost organic nitrates and compounds that increase intraplatelet cyclic

GMP levels enhance the antaggregating effects of iloprost, 839 treatment of patients with peripheral arterial occlusive disease with

intravenous iloprost and prostaglandin E,. 573 Immune system

actions of interleukin-2 on amnion prostaglandin biosynthesis. 959 comparison of hepatic splenic peritoneal and alveolar macrophages

with respect to prostaglandin E2 thromboxane B, production and antibody-dependent cellular cytotoxicity function, 149

dietary fish oil supplementation alters LTB, : LTB, ratios but does not affect the expression of acute graft versus host disease in mice. 561

effects of cysteinyl leukotriene antagonist ONO-1078 on antigen- induced responses in allergic sheep. 133

effects of new leukotriene receptor antagonist ONO-1078 on human bronchial smooth muscle in vitro. 241

effects of novel thromboxane A, receptor antagonist S-1452 on antigen-induced bronchoconstriction and airway hyperrespon- siveness in guinea-pigs. 343

fatty acids as antiinflammatory and immunomodulatory agents. 57 lupus anticoagulant and eicosanoids. 483 macrophage prostaglandin El and oxidative responses to endotoxin

during immunosuppression associated with anaesthesia and transfusion, 945

pharmacological model for airway hypersensitivity produced by propranolol and reserpine in guinea-pigs, 447

purification of human blood basophils and leukotriene C, generation following calcium ionophore stimulation, 783

role of eicosanoids in the pathogenesis of atopic dermatitis, 409 role of leukotrienes and platelet-activating factor in allergic

bronchoconstriction and their interactions in guinea-pig airway in vivo. 579

Indomethacin effect of dietary fatty acids and endotoxin on indomethacin-induced

gastrointestinal ulcers in rats, 229 effect of Slipoxygenase and cyclooxygenase blockade on porcine

haemodynamics during continuous infusion of platelet- activating factor, 549

influence on hatching of mouse blastocysta of. 683 Inflammation

airway SW WI&Y Airway arachidonic acid stimulates interleukin-6 release from rat peritoneal

macrophages in vitro: evidence for prostacyclin-dependent mechanism, 915

fatty acids as antiinflammatory and immunomodulatory agents, 57 identification of two different rate-limiting mechanisms controlling

the release of NSAlDs from silastic polymeric devices, 391 leukotriene B, generation by blood polymorphonuclear leukocytes

after incubation in urine, 761 leukotriene B, o-hydrolase activity in polymorphonuclear leuko-

cytes from patients with inflammatory bowel disease, 489 peptidoleukotrienes increase the efflux of glutathione from perfused

rat liver, 7 IS prostaglandin E2 antagonizes gingival fibroblast proliferation

stimulated by interleukin- 1 p, 847 Insulin: fatty acids may regulate aldosterone secretion and mediate

some of insulin’? effects on blood pressure. 43 Interleukins (ILsi

actions of IL-2 on amnion prostaglandin biosynthesis, 959 arachidonic acid stimulates IL-6 release from rat peritoneal macro-

phages in vitro: evidence for a prostacyclin-dependent mechanism. 9 15

effects of IL-la on arachidonic acid metabolism in human osteosarcoma osteoblastic cells. 521

epidermal growth factor and transforming growth factor-a enhance the IL- 1 - and tumour necrosis factor-stimulated prostaglandin E, production and the IL- 1 specific binding on amnion cells. 923

inhibition of the thermogenic and pyrogenic responses to IL-lp in the rat by dietary n-3 fatty acid supplementation, 6 15

IL-10 stimulates prostaglandin E, and F1, synthesis in human ovarian granulosa cells in culture, 963

Subject Index YX I

mononuclear cell-conditioned medium enhanceb thrombin- stimulated prostaglandin I2 production by human umbilical vein endothelial cell, in culture, 675

prostaglandin E, antagonizes gincgival fibroblast proliferation stimulated by IL-I p. 847

I\chuemia effect of nordihydroguaiaretic acid on leukotriene C, and

pro~taglandin EZ production following different reperfusion periods in rat brain after forebrain ischaemia correlated with morphological changes. 6.13

el’fcct of policosanol on cerebral ischaemia in Mongolian gerbils: role of prostacyclin and thromboxane A?. 695

ctfccta ot prostacyclin analogue OF’41483 on notmothermic liver ischaemia and reperfusion in,jury in rats. 317

r\aggrmtrd splanchnic prostaglandin II release following acute haemorrhagc is due to new protein synthesis. 207

pt-ostaglandin biosynthesis in the microcirculation: regulation by endothelial and non-endothelial factors. 723

thromboxane receptor antagonism and synthase inhibition in cerebral i5chaemia. 2 I I

i K

Kallidm: arachdonic acid release and inositol lipid metabolism in rer- ponsc to bradykinin and related peptides in human endometrial cell\ in vitro. 253

Keratinocyte\. human akin. endogenous prostaglandin E, modulate\ calcium-induced differentiation in. 777

Ket.>ne hodie\. possible selenium-dependent role of prostacyclin in renal handling of. 3X.5

Kldne) c ~mplcment Sa induce\ m vtvo synthrsi\ of cysteinyl leukotrienes

in rat\, 331 dtrect interaction\ between platelet5 and cultured rat mesangial cells.

5Y7 effect of dlethylnitrosamine on prostaglandin E and lipid peroxida-

tion levels in rat’s liver lung and renal tissue, 805 effect of leukotrirnes on renal water excretion. 297 effect of prostaplandin E, on renal function after cardiac surgery

involving cardiopulmonary bypass. 627 e+‘fcct\ of starvation on the urinary contents of primary thromboxane

and pro\taqclin metaboliteb and a possible selenium-dependent role lor pro\tacyclin in the renal handling of ketone bodies. 3 H S

e,ldotoxic hhoch has difftrrntial effects on renal and rplanchnic eico\nnoid synthesis. SOY

itlteraction between vitamin B6 deficiency and low essential fatty acid dietary intake on kidney phospholipids and prostaglandin EJ in the rat. 53 I

oxy-tradical\ lipid peroxides and essential fatty acids in patients with glorncrular di\order\. 603

pro\tacyclln relea\e in experimental diabetes: effects of evening primrose oil. 69Y

hodium loading and renal prostaglandins in old rats. 8 IS tiaprofcnic acid Inhibits the renal reabsorption of sulfate in rats.

S(l3

Lar/nx. meta\taGng squamous cell carcinoma of. increased thromboxane A, production at primary tumour site in. 527

Leukaemla inductlon of apoptosts in blood cells from a patient with chronic

myelogenou5 leuhaemia by selective S-lipoxygenase inhibitor SCJlh6lA. 323

trole of leukotrienes in the regulation of proliferation of normal and leukaemic haemopoietic cells. I23

Leukotrienes (LTs) antagonist ONO- 107X effects on antigen-induced responses in allergic sheep, 233 et’fects on human bronchial smooth muscle in vitro, 241 c~)mplemrnt Sa induce\ in viva bynthesis of cysteinyl LTs in rats.

331 continuouh assay of oxygen consumption used to evaluate the

pharmacology of S-lipoxypenase inhibitors, 929 dietary fish oil supplementation alters LTB,:LTB, ratios but does

not affect the expression ot acute gral’t versus ho\t dl\ense II) mice. 561

effecl of S-lipoxygenahe and cyclooxygenaar blockade on porcine hnemodynamic\ during continuou\ Infusion of platelel- activatinp factor. 539

effect of nordihydroguaiaretic actd ~111 leuhotrtene C, and prostaglandin E, production folloumf different reperfuaion period.\ in rat brain after forebrain i\chaemin correlated with morphological changes. 633

effects on renal water excretion ot. 247 induction of apoptosis in blood cells fi-om :I patient with chronic

myelo~enous leukaemis by selective S-iipox):enase inhihitot SC4lhhlA. 323

inhibitory effect of docoaahexaenoic acid-containin phospholipids on S-lipoxygenase in rat basophillc leukaemia cell\. 86 I

LTB, generation bv blood polymorphonuclc:lr lcuhocyte\ after incubation in urme. 761

LTB, co-hydrolaae activity in polymorphonuclcur Icukocytes from patients with inflammatory bowel diheahe. 3XY

measurements of LTs in human plasma b\ solid [phase extraction and hiph performance liquid chromatography. XS I

migraine and. 537 peptidoleuhotriene\ increase the efilux of plutathionc from perfujrd

rat livet-. 7 1 S pharmacological model for airway hyper\en\ttlvit! produced by

propranolol and rererpine in guinea-pi?\. 417 purification of human blood basophilh and leukotriene C, generation

following calcium ionophore stimulation. 783 role of leukotrtenes and platelet-activating factor in allergic

bronchoconstriction and their interaction\ in guinea-pi2 airway in viva. S7Y

role of leukotrienea in the regulation of prohterattoti ot normal and Ieukaemic haemopoietic cells. 12.3

Linoleic acid amplification of Gpnals from growth factor- rccepttrr\ by fatty acid\

in mammary epithelial cells. 7 1 distribution of unsaturated fatty acida in phoapholipid\ of arteries

from nonpregnant pregnant and fetal \heep. Y07 effect of ascorbate on eaential fatt! ac~i composition m B I6

melanoma cells. 77 I effect of pravastatin on fatty acid profile of Icm den\q lipoprotein

in patlents with hypercholesterolaemia. I.55 function of dietary polyunsaturated fan> acids in the nervou\

system. 5 Lipid binding protein (cytoplasmic fatty acid bmdmg protein): signifi-

cance for intracellular transport of fatty acids and putative role on Ggnal transduction pathways. 33

Lipid peroxidatton effect of diethylnitrosamme on PGE and ltpid pcroxldotton level\ in

rat’s liver lung and renal tissue. X05 effect\ of a fish oil rich diet on hyperoxic lung damage 1n mice.

96Y effect\ of fihh 011s on lipid varinhlea and platelet tunction Indices.

645 interactions between arachidonic and etc(~Siipclitaellotc acid\ during

their dioxygenase-dependent peroxidation. 23 oxy-radicals lipid peroxides and essential tatty acid\ in patient\

with plomerular disorders. 603 Lipopolysaccharide .W Endotnxm Lipoproteinth\

effect\ of fish oils on lipid variables and platelet function in&cc\. 615

effect5 of pravastatin on fatty actd profile of low density lipopl-otein in patients with hypercholesterolaemia. I SS

lipoprotems from normolipldaemic and dyslipidaemic \uhjects modify the thromboxane A, generation hy platelet\ in clottins human blood, 475

putative role of dietary omega-.< pol~u~~~aturated fatty acid\ in oxidati\ e modification of low density lipoprotem. iY7

Liver comparison of hepatic splenic peritoneal and alveolar macrophages

with respect to prostaglandm E, thromboxane B, productton and antibody-dependent cellular cytotoxicity function. 14~

effect of diethylnitrosamine on proataglandin E and lipid peroxidation levels in rat‘, Ilver lung and renal ttbsue. XOS

effects of prostacyclin analogue OP-413X3 r,n normothermic livet- i\chaemia and reperfuslon in,jur!J in rat\. II 7


function of dietary polyunsaturated fatty acids in the nervous system, 5

peptidoleukotrienes increase the efflux of glutathione from perfused rat liver, 715

prostaglandin and portal hypertension. 203

Lung(s) effect of diethylnitrosamine on prostaglandin E and lipid

peroxidation levels in rat’s liver lung and renal tissue, 805 effect of a fish oil rich diet on hyperoxic lung damage in mice, 969 effect of 5-lipoxygenase and cyclooxygenase blockade on porcine

haemodynamics during continuous infusion of platelet- activating factor, 549

hyperoxia decreases cyclooxygenase activity in endothelial cells. 455

prostacyclin release in experimental diabetes: effects of evening primrose oil, 699

prostaglandin IZ production and angiotensin converting enzyme activity in cultured porcine pulmonary artery endothelial cells treated with paraquat, 291

short chain fatty acid-induced hyperventilation is due to prostaglandin Fzu. 833

Lupus anticoagulant, eicosanoids and, 483

M

Macrophages arachidonic acid stimulates interleukin-6 release from rat peritoneal

macrophages in vitro: evidence for prostacyclin-dependent mechanism. 915

comparison of hepatic splenic peritoneal and alveolar macrophages with respect to prostaglandin E2 thromboxane BZ production and antibody-dependent cellular cytotoxicity function. 149

macrophage prostaglandin E, and oxidative responses to endotoxin during immunosuppression associated with anaesthesia and transfusion, 945

Mammary tissue see Breast Mastalgia, effects of gamma-linolenic acid on. 101 Membrane(s). cell

dynamics of the membrane lipid phase, 27 function of dietary polyunsaturated fatty acids in the nervous

system, 5 physicochemical approach of the function of the fatty acid incor-

poration in biological membranes, 17 prostaglandin FZu synthesis in the hippocampal mossy fibre

synaptosomal preparation and, 127 see also Signal transduction

Microcirculation, prostaglandin biosynthesis in. 723 Migraine: implication of arachidonic acid metabolites. 537 Mouth

expression of prostaglandin Ez receptor in hamster buccal pouch and effects of benzo(a)pyrene and nicotine, 82 1

prostaglandin E?, antagonizes gingival fibroblast proliferation stimulated by mterleukin-lB, 847

Mucin synthesis and secretion by an intestinal goblet cell line, effect of 16.16-dimethylprostaglandin E? on, 423

Multiple organ failure: exaggerated splanchnic prostaglandin I? release following acute haemorrhage is due to new protein synthesis, 207

Muscle(s) arachidonic acid inhibit electrically-induced intracellular calcium

transients in neonatal rat cardiomyocytes, 837 cancer cachexia: interaction between eicosapentaenoic acid and

inhibitory guanine nucleotide-regulatory protein, 105 changes in phospholipase A, activity of the rabbit ampullary

epithelium by ovarian steroids. 3 15 effect of endothelium removal on basal and muscarinic cholinergic

stimulated rat mesenteric vascular bed prostanoid synthesis, 373

effects of new leukotriene receptor antagonist ONO-1078 on human bronchial smooth muscle in vitro, 241

eicosapentaenoic acid abolishes the proatherogenic effects of cholesterol: effects on migration of bovine smooth muscle and endothelial cells in vitro, 463

SC-46275: a potent and highly selective agonist at the EP3 receptor. 939

Mutagenesis: prostacyclin as a potent anti-mutagen, 175

N

Nervous system effects of gamma-linolenic acid on breast pain and diabetic

neuropathy, 101 function of dietary polyunsaturated fatty acids in the nervous

system. 5 prostacyclin release in experimental diabetes: effects of evening

primrose oil. 699 prostaglandin FZa synthesis in the hippocampal mossy fibre

synaptosomal preparation. 127. 877 see also Brain

Nicotine, effect on prostaglandin Ez receptor expression in hamster buccal pouch of, 82 1

Non-steroidal anti-inflammatory drugs (NSAIDs) effect of policosanol on cerebral ischaemia in Mongolian gerbils:

role of prostacyclin and thromboxane Al, 695 effects of regular and enteric-coated aspirin on bleeding time

thromboxane and prostacyclin. 5 15 identification of two different rate-limiting mechanisms controlling

the release of NSAIDs from silastic polymeric devices, 391 migraine and. 537 protective effect of diclofenac sodium against endotoxic shock in

anaesthetized pigs, 193 tiaprofenic acid inhibits the renal reabsorption of sulfate in rats, 503

Nordihydroguaiaretic acid: effect on leukotriene C, and prostaglandin El production following different reperfusion periods in rat brain after forebrain ischaemia correlated with morphological changes. 633

0

Oestrogenioestradiol changes in phospholipase A1 activity of the rabbit ampullary

epithelium by ovarian steroids, 3 15 effects of guinea-pig endometrial proteins on phospholipase Al

activity and prostaglandin synthesis, 219 modulation by sex hormones of the membranous transducing system

regulating fatty acid mobilization in adipose tissue. 91 role of free fatty acids in regulating the tissue availability and

synthesis of sex steroids. 111 Oral cavity see Mouth Osteoporosis: effects of glucocorticoid on signalling by prostaglandin

El in osteoblast-like cells, 867 Osteosarcoma osteoblastic cells. effects of interleukin-la on

arachidonic acid metabolism in, 521 Ovary

arachidonic acid and cell signalling in the ovary and placenta. 79 changes in phospholipase A? activity of the rabbit ampullary

epithelium by ovarian steroids, 315 eicosanoids and ovulation, 827 IL-ID stimulates prostaglandin & and F2a synthesis in human

ovarian granulosa cells in culture, 963 Oviducts

changes in phospholipase A, activity of the rabbit ampullary epithelium by ovarian steroids, 315

immunohistochemical localization in rat of prostaglandin Fz,, receptor in, 185

Ovulation, eicosanoids and, 827 Oxygen radicals see Free radicals

P I

Pain: effects of gamma-linolenic acid on breast pain and diabetic neuropathy: possible non-eicosanoid mechanisms, 101

Paraquat, effect on prostaglandin IZ production and ACE activity in cultured porcine pulmonary artery endothelial cells of. 291

Peritoneal macrophages arachidonic acid stimulates interleukin-6 release from rat peritoneal

macrophages: evidence for a prostacyclin-dependent mechanism, 915

comparison of hepatic splenic peritoneal and alveolar macrophages with respect to prostaglandin E2 thromboxane B1 production and antibody-dependent cellular cytotoxicity function, 149

Subject Index 9X3

Peroxidation .SW Lipid peroxidation Phosphoinositides: arachidonic acid release and inositol lipid meta-

bolism in response to bradykinin and related peptides in human endometrial cells m vitro. ?S.?

Phospholipahe Az changes m pho\pholipase AI activity of the rabbit ampullary

epithclium by ovarian steroids, 315 dietary sunflower linseed and fish oils affect phospholipid fatty acid

composition development of cardiac lesions phospholipase activity and eicosanoid production in Atlantic salmon. 665

effects of guinea-pig endometrial proteins on phospholipase A, activity and prostaglandin synthesis. 219

possible cros+refractoriness between phospholipase A2 and the calcium ionophore ‘423187 in the stimulation of uterine prostaglandin production. 327

prostaglandin F, (I synthesis in the hippocampal mossy fibre synaptosomal preparation and. 127. X77

Placenta. arachidonic acid and cell signalling in the ovary and, 79 Platelet(s)

anti-platelet and anti-thrombotic effects of prostacyclin analogue OP-4148.1. a-CD in experimental animals. 795

antiplatelet components isolated from oil of cloves. 363 arachidonic acid supplementation dose-dependently reverses the

effect\ of a butter-enriched diet in rats. 247 calcium homeostasis and eicosanoid formation in. 277 direct interaction\ between platelets and cultured rat mesangial cells,

597 effect\ of fish oils on lipld variables and platslet function indices,

645 effect\ 01 garlic-derived principle ajoene on aggregation and

arachldonic acid metabolism in human blood platelets. 587 effect\ of genistein on platelet function are due to thromboxane

receptor antagonism rather than inhibition of tyrosine kinase. 319

IS-115 ab a thromboxane A, antagonist. 439 lipoprotein\ from normolipidaemic and dyslipidaemic subjects

modIf!{ the thromboxanc A2 generation by platelets in clotting human blood, 475

organic nitrates and compounds that increase intraplatelet cyclic GMP level\ enhance the antiaggregating effects of iloprost, X39

Platelet-activating factor (PAFI direct interaction\ between platelets and cultured mt mesanpial cells.

597 effect of Slipoxygenase and cyclooxygenase blockade on porcine

haemodynamics during continuous infusion of PAF. 549 PAF-induced death in NMRI mice: a suitable shock model for

testing new PAF receptor antagonists. 265 protective effect of diclofenac sodium against endotoxic shock in

anaesthetized pigs, 193 role of lrukotrienes and PAF in allergic bronchoconstriction and

their interactions in guinea-pig airway in viva. 579 Pohcosanol. effect on cerebra1 ischaemia in Mongolian gerbils of, 695 Polymorphonuclear leukocytes

leukotriene B, generation following incubation in urine, 761 Icukotrienc B4 to-hydrolase activity in cells from patients with

inflammatory bowel disease. 4X9 Polyunsaturated fatty acids .WJ Fatty acids Portal hypertension. prostaglandins and, 203 Potassium (K-1

effect of lcuhotrienes on renal water excretion. 297 relationship between factors influencing Na+-K+-ATPase activity

and eicosanoid production from “‘C-AA in spayed rat uteri, 27.1 Pra>,astatin. ct’fect on fatty acid profile of low density lipoprotein in

patients with hypercholesterolaemia. 155 Pre-eclamptic patient,. effect of dietary primrose oil or fish oil in, 691 Pregnancv

a<tio&of. interleukin-2 on amnion prostaglandin biosynthesis. 959 arachidonic acid and cell signalling in the ovary and placenta. 79 dietary supplementation with primrose oil or fish oil does not

change urinary excretion of prostacyclin and thromboxane metabolites m pre-eclamptic women. 691

dl\tribution of unsaturated fatty acids in phospholipids of arteries from nonpregnant pregnant and fetal sheep, 907

eifect of chrome ethanol consumption on the spontaneous contraction5 prostaglandin production triglycerides and glucose

metabolism of uterine strips isolated from pregnant ra~a and in embryo\. 495

epidermal growth factor and tramfonnin, c 17 urowth factor-a enhance the interleukin- I and tumour necrosis factor-stimulated prostaglandin E, production and the interleukin-1 specific binding on amnion cells. 923

influence of indomethacin on hatching of mouse blaLtoc?sts. 6X3 lipid intake during pregnancy in developing countries: possible

effect of essential fatty acid deficiencv on fetal growth. 139 protein kinase A activators inhibit agonist-induced prostaplnndin

production in human amnion. 355 synthesis of 12.hydroxyeicosatetraenoic acid by human decidua and

endometrium. 609 Progesterone: changes in phospholipase A, activity ot the rabbit

ampullary epithelium by ovarian steroids. 3 IS Propranolol and reserpine. experimental nir\\ay hyperrenctlvit! model

produced by. 447 Prostacyclin (prostaglandin I?: PGI,)

anti-platelet and anti-thrombotic effect? of prostacyclin analopue OP-41483.a.CD in experimental animals. 795

arachidonic acid stimulates interleukin-6 release from rat peritoneal macrophagrb: evidence for ii prostacyclin-dependent mechanism, 9 IS

arachidonic acid supplementanon do\e-dependenti! revcr\e\ the effects of a butter-enriched diet in rat\. 247

comparison of the potency of variou\ serotypes ol’ E. (JI lipopolysaccharides in stimulating PGI, production and suppreas- ing ACE activity m cultured human umhilicnl vein endothelinl cells. 955

dietary supplementation with primrose oil or t&h oil doe\ not change urinary excretion of proatacqclin and thromboxane metabolites in pre-eclamptic women, 691

effect of endothelium removal on basal and mu\carmic choline@ stimulated rat mesenteric vascular bed prostanold synthe\i\. 373

effect of policosanol on cerebral ischaemia in Mongolian gerbils: role of prostacyclin and thromboxane A,. 695

effect of prostacyclin analogue OP-41483 on normothermlc liver ihchaemia and reperfusion injury in rats. -1 I7

effect of regular and enteric-coaxed aspirin on bleeding time thromboxane and proatacyclin. 5 I5

effects of Qarvution on the urinary content5 oi primar) thmmboxane and prostacyclin metabohtes and ;I possible \clenium- dependent role of prostacyclin in the renal handling ot hctonc bodies, 385

endotoxic ahock has differential effect\ on renal and splanchnic eicosanoid synthesis. SO9

exaggerated splanchnic PGI, release followin, L o ‘icute haemorrhage ia due to new protein synthesis. 207

migraine and. 537 mononuclear cell-conditioned medium enhances thrombin-

stimulated PGI, production by human umbilical vein endothelial cells in culture. 675

pharmncokmetics and pharmacodynamics ot the proqtacyclin analogue lSAU81 in the anaesthetized beagle dog. 159

portal hypertension and. 203 as potent anti-mutagen. I75 prostacyclin regulates bplanchnic blood tlow during early

haemorrhage/reperfusion injury, 401 prostacyclin release in experimental diabete\: effect\ of evening

primrose oil. 699 PGI, production and angiotensm convertmg enzyme actlvlty in

cultured porcine pulmonary artery endothelial cell5 ireated with paraquat. 29 I

radioimmunoaasay for the prostacyclin analoeuc 1 SAUX I : ;I preliminary pharmacokinetics study in the dog. 167

Type A behaviour and alcohol consumption: effect:. on resting and post-exercise bleeding time thromhouane and prostacyclin metabolites. 133

src O/.W Iloproht Prostaglandin D, and endothelin- I induce pro\tanoid production in

capillary endothelium of human brain, 7X9 Prostaglandin E, (PGE, 1

effect of diethylnitrosamine on PGE and llpltl peroxidatlon levels in rat’s liver lung and renal tissue. 805

effect of PGE, on renal function after cal-disc surgery involving cardiopulmonary bypass. 627


epidural blood flow during PGE,- or trimethaphan-induced hypotension, 873

migraine and, 537 Prostaglandin El (PGE?)

and amplification of signals from growth factor receptors by fatty acids in mammary epithelial cells. 71

bimodal regulation of adenylate cyclase by PGE, receptors in porcine ciliary epithelium. 765

changes in gastric mucosal histamine and PGE,-like activities in relation to portal somatostatin following small bowel resection in guinea-pigs. 3 19

comparison of hepatic splenic peritoneal and alveolar macrophages with respect to PGE, and thromboxane B2, production and antibody-dependent cellular cytotoxicity functton. 149

dietary sunflower linseed and fish oils affect phospholipid fatty acid composition development of cardiac lesions phospholipase activity and eicosanoid production in Atlantic salmon, 665

effect of diethylnitrosamine on PGE and lipid peroxidation levels in rat’s liver lung and renal tissue, 805

effect of 16,16-dimethyl PGE, on proliferation of an intestinal goblet cell line and its synthesis and secretion of mucin glycoproteins. 423

effect of glucocorticoid on signalling by PGE, in osteoblast-like cells, 867

effect of interleukin-lcx on arachidonic acid metabolism in human osteosarcoma osteoblastic cells. 52 1

effect of nordihydroguaiaretic acid on leukotriene C, and PGE, production following different reperfusion periods in rat brain after forebrain ischaemia correlated with morphological changes, 633

endogenous PGEz modulates calcium-induced differentiation in human skin keratinocytes. 777


enhancement of antineoplastic effect and attenuation of sister chromatid exchanges by PGEz in Ehrlich ascites tumour cells treated with cyclophosphamide in vivo. 707

epidermal growth factor and transforming growth factor-a enhance the interleukin-l- and tumour necrosis factor-stimulated PGE, production and the interleukin-1 specific binding on amnion cells, 923

expression of PGEz receptor in hamster buccal pouch. effect of benzo(a)pyrene and nicotine on. 82 1

hyperoxia decreases cyclooxygenase activity in endothelial cells. 455 inhibition of gingival fibroblast proliferation stimulated by

interleukin-lb, 847 interaction between vitamin B6 deficiency and low essential filtty

acid dietary intake on kidney phospholipids and PGEl in the rat. 531

interleukin-lp stimulates PGE? and PGF?, synthesis in human ovarian granulosa cells in culture, 963

macrophage PGEz and oxidative responses to endotoxin during immunosuppression associated with anaesthesia and transfusion, 945

modulation’of PGE?-induced Ca” influx by steroid hormones in osteoblast-like cells. 711

possible cross-refractoriness between phospholipase AZ and the calcium ionophore A23187 in the stimulation of uterine prostaglandin production, 327

prostaglandin Dz and endothelin- 1 induce prostanoid production in capillary endothelium of human brain. 789

protein kinase A activators inhibit agonist-induced prostaglandin production in human amnion, 355

relationship between factors influencing Na+-K+-ATPase activity and eicosanoid production from ‘IC-AA in spayed rat uteri, 273

SC-46275: a potent and highly selective agonist at the EP3 receptor, 939

sodium loading and renal prostaglandins in old rats. 8 15 and tiaprofenic acid inhibition of renal sulfate reabsorption in rats,

503 treatment of patients with peripheral arterial occlusive disease with

intravenous iloprost and PGE,. 573 6-keto-Prostaglandin F,,

acute haemorrhage induces increased release of, 207. 401 anti- mutagenic action of prostacyclin and, 175

effects of starvation on the urinary contents of primary thromboxane and prostacyclin metabolites and a possible selenium-

dependent role of prostacyclin in the renal handling of ketone bodies, 385

hyperoxia decreases cyclooxygenase activity in endothelial cells. 455

in metastasizing squamous cell carcinoma of the larynx. 527 possible cross-refractoriness between phospholipase A? and the

calcium ionophore A23187 in the stimulation of uterine prostaglandin production. 327

relationship between factors influencing Nat-K+-ATPase activity and eicosanoid production from “‘C-AA in spayed rat uteri. 273

sodium loading and renal prostaglandins in old rats. 8 15 Type A behaviour and alcohol consumption: effects on resting and

post-exercise bleeding time thromboxane and prostacyclin metabolites, 143

Prostaglandin F:,, (PGF,,) effects of guinea-pig endometrial proteins on phospholipase A2

activity and prostaglandin synthesis. 219 in hippocampal mossy fiber synaptosomal preparation. 127. 877 immunohistochemical localization of PGF,, receptor in the rat

oviduct. 185 interleukin-1B stimulates PGEz and PGF,, synthesis in human

ovarian granulosa cells in culture. 963 possible cross-refractoriness between phospholipase A2 and the

calcium ionophore A23187 in the stimulation of uterine prostaglandin production, 327

prostaglandin D1 and endothelin- 1 induce prostanoid production in capillary endothelium of human brain. 789

relationship between factors influencing Na+-K+-ATPase activity and eicosanoid production from “‘C-AA in spayed rat uteri, 273

and short chain fatty acid-induced hyperventilation. 833 Prostaglandin I2 see Prostacyclin Protein kinase(s) (PK)

and amplification of stgnals from growth factor receptors by fatty acids in mammary epithelial cells, 7 1

prostaglandin FI, synthesis in the hippocampal mossy fibre synaptosomal preparation and, 127

PKA activators inhibit agonist-induced prostaglandin production in human amnion, 355

PKC and role of fatty acids in signal transduction, 117

R

Red blood cell deformability, in vitro effect of triacylglycerols on, 35 1 Renal function see Kidney Reserpine and propranolol. experimental airway hyperreactivity model

produced by. 447 Respiratory tract srr Airway: Lung Retinoic acid: modulation of prostaglandin E,-induced calcium influx

by steroid hormones in osteoblast-like cells, 71 1

S

SC-46275: a potent and highly selective agonist at the EP3 receptor, 939

Selenium: effects of starvation on the urinary contents of primary thromboxane and prostacyclin metabolites and a possible selenium-dependent role of prostacyclin in the renal handling of ketone bodies. 385

Sex hormones see WI&~ Steroids Shock

complement 5a induces in vivo synthesis of cysteinyl leukotrienes in rats. 33 1


exaggerated splanchnic prostaglandin I, release following acute haemorrhage is due to new protein synthesis, 207

platelet-activating factor-induced death in NMRI mice: a suitable shock model for testing new PAF receptor antagonists, 265

protective effect of diclofenac sodium against endotoxic shock in anaesthetized pigs, 193

Signal transduction amplification of signals from growth factor receptors by fatty acids

in mammary epithelial cells. 7 I arachidonic acid and cell signalling in the ovary and placenta. 79 cytoplasmic fatty acid binding protein: significance for intracellular

Subiect Index YX5

transport ot fatty acids and putative role on signal transduction

pathways. 33

effects of glucocorticoid on signalling by prostaglandin E, in osteoblast-llke cells. 867

fatty acids and. I modulation by WY hormones of the membranous transducing system

reglating fatty acid mobilization in adipose tissue, 91 ,-oIc of fAtty acids in Ggnal transduction: modulators and

me\\engerr. I 17

SiLtic polymeric device\. relcase of NSAIDs from, 391

Skin rndogrnouh prostaglandin E, modulates calcium-induced differen-

tiation in human keratinocytes. 777 -ale of eicosanoids in the pathogenesis of atopic dermatitis, -109

Smohe. cigarette: expression of prostaglandin El receptor in hamster buccal pouch and effects of benzo(a)pyrene and nicotine. 821

Sodium (Na’)

Jffect of leuhotrienrs on renal hater excretion. 197

.elation\hip between fActor\ influencing Na+-K+-ATPase activity and elcosanoid production from “C-AA in spayed rat uteri. 273

.odiurn loading and renal prostaglandins in old rats. 8 I.5 Somatostatin. portal: and change\ in pa\tric mucosal histamine and

pro\taplandin El-like activities following small bowel resection m gumea-pigs. 3 I9

Spice: antiplatelet components iaolated from oil of cloves. 363 Splnc: epidural bl,,od flow durme prostaglandin E,- or trimethaphan-

induced hypotenfion. X73 Spleen: comparison of hepatic splenic peritoneal and alveolar macro-

phagca with respect to prostaglandin E, thromboxane B, pro-

duction and antibody-dependent cellular cytotoxicity function. 1-i’)

Steroid\

changes m phospholipasc A2 activity of the rabbit ampullary

cpithclium by ovarian bterolds. 3 IS

s:ffrct\ of glucocorticoid on GgnaUing by prostaglandin El in osteoblabt-like cells. 867

cffcct\ 01 puinea-pig endometrial proteina on phosphollpase A, acts\ It? and prostaclandin synthesis. 219

‘ret‘ fattv acid\ as modulators of the steroid hormone message, 63 motlulat~ion of prostaglandin E,-induced C$+

hormones in osteobla+like cells. 7 I I influx by steroid

modulation by sex hormones of the membranous transducing system

rcpulating tatty acid mobilization in adipose tissue. 91 role of tree fatty acids in rrpulatin y the tissue availability and

\!;nlhesi\ of \ex steroid\. I I I Swfa~lle. el’fccr in r;~ts of tiaprofenic acid on renal reabsorption of. 503

1 L I _______

modulation by wx hormonea of the membranous transducing system

rc@stinp fatty acid mobilization in adipose tissue, 91

role of Iree fatty acid\ in regulatin, * the tissue availability and

\)nthesi\ of WY steroids, I I I Th)-omboxane( \)

:mtiplatelct component\ iaolated from oil of cloves and. 363 arnchidonlc acid stimulate\ interleuhin-6 release from rat peritoneal

macrophage\ in vitro: evidence for a prostacyclin-dependent mcchani\m. Y Ii

;Irachidon,c acid supplementation dos-dependently reverses the

effect\ of a butter-enriched diet in rats. 747

~ompariwn of hepatlc \plenic peritoneal and alveolar macrophages

uith re\prct to pro\taplandin E, TXB, production and antihodq-dependent cellular cytotoxicity l&ion. I19

tlietq ~unIlo~.cr linseed and fish oil\ affect phospholipid fwy acid

compo\ltion development of cardiac lesion5 phospholipase ,icti\ 11) and rico\anoid productlon m Atlantic salmon. 66.5

(lietar) \upplementatlon with primrose oil or- fish oil does not chanpc urinary ew-enon of proktacyclin and thromboxane

nict:iholite\ in pre-eclaniptic women. 691 (Ii!-ect Intcmction\ bctwccn plalelct\ and cultured rat rnewngial cell\.

5Y7

t,ffecr o1’ sndothclium removal on basal and muscarinic cholineryic

\tlmulaced rat meaenteric vascular bed pro,tanoid syntheG\. 373 <,fiect 01 ~arl1~.-deri\ ed principle qjoene on aegregatlon and

.Ira~~h1d~m1c acid metaboliwl in human bl~wd platclcts. 5X7

effect of genistein on platelet function are due to thromboxane

receptor antagonism rather than inhibitton ot tyroi;ine hinase.

379 effect of S-lipoxygenase and cyclooxygenase blochade on porcine

haemodynamics during continuou\ infusion of platelet- activating factor. 519

effect of novel TXA, receptor antagomst S-l-152 on antigen-induced

bronchoconstriction and airway hyperre~pon\ivene~~ in guinea-

pigs. .il?

effect of regular and enteric-coated a\pirm on bleedin: time

thromboxane and prostacyclin. 5 IS effect of policosanol on cerebral i\chacmln in Mongolian gerbil\:

role of prostacyclin and TXA,. 6Y.5 effect\ of \tarvation on the urinary content\ of primarv thromboxanc

and pro>tacyclin metabolites and a pob\iblc \el&iurn-dependent role ofprostacvclin in the renal hondlmg of ketone hodie\. 3X5

evening primrose UII and fish oil in non-inwlir dependent dlnbetc\. 56’)

importance of secondary TXA, release in medlatinz cndothclin- I

induced bronchoconstrlclion and va\opres<in in the guinea-pig.

761 incrcawd TXA, production at primary Iumour \itc in metast,l\lzine

rquamous cell carcinoma of the Iar>nz. 527

ingestion of marine oil reduce\ intravaaculnr production ot T.XAy a>

measured by I I-dehydrothromboxane By c\cI-ction. 3115 IS- l-15 a5 a TXA, antagonist. -1.3’)

lipoprotein\ from normolipidaemic and dy\lipidaemic subject\ modify the TXA, generation by platclrr\ in clotnng human

blood. 17.5 migraine and. 537

pharmacological model for airway hyper\m\lti\ It) produced h! propranolol and reserpine in guinea-pig\. d-l7

prostaglandin D1 and endothelin- I induce prostanold production m capillary endothelium of human brain. 7W

relatmnhhip between factors inlluencing Nn--K’-.4TPaw activity and eicosanoid production from “C-.4.4 in spayed rat uteri. 27;

sodium loading and renal prostaglandms rn old ratb. x I5 thromboxane receptor antagonism and \vnthaw inhIbItion in

ccl-cbral ischaemia. 21 I

Type A behavlour and alcohol consumprion: ctfect\ on rr\ting and

po\t-cwrclse bleedmg time thromh~~\anc and prortacyclin metabolite\. I-13

U lh6lY induce\ different blood prewuc cftwt\ m mnlc and lemale spontaneously hypertensive rat\. 169

Tiaprofenic acid inhlbltc the renal reabwrpnon 01 \uli’atc m rat\. 503 T-lymphocyte\: faq acld’r ;I\ .t~itiinllammut~,I-! snd immunomo-

dulatory agent\. 57 Transforming growth factor-C( and ep~dermal grou th factor enhance

the interleuhin- I ;rnd TNF-\tlmulatcd pro<taglandin t, pro-

duction and the interleuku- I \pecific handing on amnion cell\.

02.:

Transfusion. blood. macropha~c pro\taglanclin E, and oxuJativc

I-eaponsea to endotoain durmg ilnrnullo\upllrr~~ion a\\ociated v. ith anar\thesia and. Y-L5

Triacylplycerol~. effect on erythrocyte deformatnllt! 01. .<5 I Trimethaphan- or pro\taglandin E,-induced h!iwtcn\ion. sp1dural

bl~~od tlou durin?. S7.3 Tumour( ~)/canwr

cancer cachexla: interaction bet-ecn I’Ico\:Ipclllaelloic acid and mhlbitorq puanine nucleotlde-reeular(~r~ platein, 105

effect ot ascorbatc on e\wntlal I’M> ;ICI<I c~w~po\ltitrn in Blh

melanoma cells. 77 I


role of free fatty acids in regulating the tissue availability and synthesis of sex steroids, 111

role of leukotrienes in the regulation of proliferation of normal and leukaemic haemopoietic cells, 123

Tumour necrosis factor (TNF) epidermal growth factor and transforming growth factor-o enhance

the interleukin-l- and TNF-stimulated prostaglandin E, production and the interleukin- 1 specific binding on amnion cells. 923

mononuclear cell-conditioned medium enhances thrombin- stimulated prostaglandin I? production by human umbilical vein endothelial cells in culture, 675

protective effect of diclofenac sodium against endotoxic shock in anaesthetized pigs. 193

Type A behaviour and alcohol consumption: effects on resting and post-exercise bleeding time thromboxane and prostacyclin metabolites, 143

Tyrosine kinase amplicication of signals from growth factor receptors by fatty acids

in mammary epithelial cells, 7 1 effects of genistein on platelet function are due to thromboxane

receptor antagonism rather than inhibition of tyrosine kinase. 379

U

Ulcers effect of 16,16-dimethyl prostaglandin El on proliferation of an

intestinal goblet cell line and its synthesis and secretion of mucin glycoproteins, 423

indomethacin-induced gastrointestinal ulcers in rats: effects of dietary fatty acids and endotoxin. 229

leukotriene B, o-hydrolase activity in polymorphonuclear leukocytes from patients with inflammatory bowel disease. 489

Urinary tract aqueous extracts of garlic inhibit prostaglandin synthesis in the

ovine ureter. 855 inflammation: leukotriene B, generation by blood polymorpho-

nuclear leukocytes after incubation in urine. 761 see also Kidney

Urine dietary supplementation with primrose oil or fish oil does not

change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women, 691

effect of leukotrienes on renal water excretion, 297 effects of starvation on the urinary contents of primary thromboxane

and prostacyclin metabolites and a possible selenium- dependent role of prostacyclin in the renal handling of ketone bodies. 385

ingestion of marine oil reduces intravascular production of thromboxane A2 as measured by 1 I-dehydrothromboxane B, excretion, 305

leukotriene B, generation by blood polymorphonuclear leukocytes after incubation in urine. 761

sodium loading and renal prostaglandins in old rats. 8 15 Uterus

actions of interleukin-2 on amnion prostaglandin biosynthesis. 959 arachidonic acid and cell signallinp in the ovary and placenta. 79 arachidonic acid release and inositol lipid metabolism in response to

bradykinin and related peptides in human endometrial cells in vitro, 253

distribution of unsaturated fatty acids in phospholipids of arteries from nonpregnant pregnant and fetal sheep. 907

effect of chronic ethanol consumption on the spontaneous contractions prostaglandin production triglycerides and glucose metabolism of uterine strips isolated from pregnant rats and in embryos. 195

effects of guinea-pig endometrial proteins on phospholipa\r A, activity and prostaglandin synthesis. 219

identification of two different rate-limiting mechanisms controlling the release of NSAIDs from silastic polymeric devices. 391

possible croa\-refractoriness between phospholipase A, and the calcium ionophore A23187 in the stimulation of uterine prostaglandin production. 327

relationship between factors inlluencing Na’-K’-ATPase activity and cicosanoid production from “C-AA in spayed rat uteri. 173

synthesis of 12-hydroxyeicosatetraenoic acid by human decidua and endometrium. 609

V

Vascular system anti-platelet and anti-thrombotic effects of prostacyclin analogue

OP-41483.a-CD in experimental animals. 795 comparative study of diets enriched with evening primrose

blackcurrant borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats. 809

comparison of the potency of various serotypes of E. c,o/i lipopolysaccharides in stimulating prostaglandin Iz production and suppressing ACE activity in cultured human umbilical vein endothelial cells. 955

dietary supplementation with primrose oil or fish oil does not change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women. 691

distribution of unsaturated fatty acids in phospholipids of arteries from nonpregnant pregnant and fetal sheep, 907

effect of endothelium removal on basal and muscarinic cholinergic stimulated rat mesenteric vascular bed prostanoid synthesis, 373

effect of 5-lipoxygenase and cyclooxygenase blockade on porcine haemodynamics during continuous infusion of platelet- activating factor. 549

effect of nordihydroguaiaretic acid on leukotriene C, and prostaglandin E2 production following different reperfusion periods in rat brain after forebrain ischaemia correlated with morphological changes, 633

effect of policosanol on cerebral ischaemia in Mongolian gerbils: role of prostacyclin and thromboxane AZ. 695

effect of prostacyclin analogue OP-41483 on normothemric liver ischaemia and reperfusion injury in rats. 417

effect of prostaglandin E, on renal function after cardiac surgery involving cardiopulmonary bypass. 627

effect of regular and enteric-coated aspirin on bleeding time thromboxane and prostacyclin. 5 15

effect of triacylglycerols on erythrocyte deformability. 35 1 eicosapentaenoic acid abolishes the proatherogenic effects of cholesterol: effects on migration of bovine smooth muscle and endothelial cells in vitro. 463

eicosapentaenoic acid and atherosclerosis. 337 endotoxic shock has differential effects on renal and splanchnic

eicosanoid synthesis. 509 epidural blood flow during prostaglandin E,- or trimethaphan-

induced hypotension. 873 exaggerated splanchnic prostaglandin I? release following acute

haemorrhage is due to new protein synthesis. 207 hyperoxia decreases cyclooxygenase activity in endothelial cells. 455 importance of secondary thromboxane A, release in mediating

endothelin- 1 -induced bronchoconstriction and vasopressin in the guinea-pig. 261

ingestion of marine oil reduces intravascular production of thromboxane Al a5 measured by 1 I-dehydrothromboxane B2 excretion. 305

lipoproteins from noimolipidaemic and dyslipidaemic subjects modify the thromboxane Al generation by platelets in clotting human blood. 375

lupus anticoagulant and eicosanoida. 383 macrophage prostaglandin E2 and oxidative responses to endotoxm

during immunosuppression associated with anaesthesia and transfusion 945

mononuclear cell-conditioned medium enhance\ thrombin- stimulated prostaglandin I, production by human umbilical vein endothelial cells in culture. 675

pharmacokinetics and pharmacodynamics of the prostacyclin analopue I.SAUX 1 in the anaesthetired beagle dog, 1.59

prostacyclin regulates splanchnic blood Bow during early haemorrhuge/reperfusion injury. 401


pro\taglandin biosynthesis in the mici-ocirculation: regulation by endothelial and non-endothelial factors. 723

prostaplandm D, and cndothelin-I induce prostanoid production in capillary endothelium of human brain. 789

Subject lnde\ 987

prostaglandin 1, production and angiotensin converting enzyme activit! in cultured porcine pulmonary artery endothelial cells treated with paraquat. 291

prostaglandins and portal hypertension, 203 protective effect of diclofenac sodium against endotoxic shock in

anaesthetized pigs. 143 radioimmunoa\say for the pro\tacyclin analogue ISAUX 1: a

preliminary pharmacokinetica study in the dog, 167 thromhoxane receptor antagonism and Eynthase inhibition in

cerebral i\chaemia. 21 I treatment ot patient\ with peripheral arterial occlusive disease with

mtravcnoub ilopro\t and prostaglandin E,. 573

U 46619 inducds different blood pressure effecti; In male and female spontaneously hypertensive rats. 169

.ser U/JO Atherosclerosi\ Vitamin Bh deficiency. interaction between IOM e\\ential fan) acid

dietary intake and. 53 1 Vitamin C (ascorbate). effect on e\wntial fart! acid composition in

B 16 melanoma cell\ of. 77 I

Water excretion. effect of leukotriener on. 37

Date post:	31-Dec-2016
Category:	Documents
Upload:	ngodieu
View:	235 times
Download:	6 times

Subject index to volume 48 and 49

Documents