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SURGERY TODAY Quarterly Newsletter of The Ohio State University Department of Surgery November 2010 • Volume 19, Number 4 Dr. Robert M. Zolliger, Jr., professor emeritus, Department of Surgery, Case Western Reserve University School of Medicine and University Hospitals, Cleveland, Ohio, and Dr. E. Christopher Ellison, the Robert M. Zollinger professor and chairman of surgery, associate vice president for health sciences, and vice dean of clinical affairs at The Ohio State University Medical Center pose with the newly released 9th Edition of the Zollinger’s Atlas of Surgical Operations. Behind them hangs a portrait of Dr. Robert M. Zollinger, Sr. INSIDE: 2 OSU Surgeon among first to perform procedure 3 Dr. Higgins shares vision at town meeting 4 Microsurgery in the laboratory 5 Spotlight on staff: Heidi Pieper 7 Second Annual Ruberg Symposium
Transcript
Page 1: SURGERY TODAY - Ohio State University TODAY Quarterly Newsletter ... MINIMALLY INVASIVE SURGERY OSU Surgeon first to perform procedure ... Advantages to natural orifice surgery include

SURGERY TODAYQuarterly Newsletter of The Ohio State University Department of SurgeryNovember 2010 • Volume 19, Number 4

Dr. Robert M. Zolliger, Jr., professor emeritus, Department of Surgery, Case WesternReserve University School of Medicine and University Hospitals, Cleveland, Ohio, andDr. E. Christopher Ellison, the Robert M. Zollinger professor and chairman of surgery,associate vice president for health sciences, and vice dean of clinical affairs at TheOhio State University Medical Center pose with the newly released 9th Edition of theZollinger’s Atlas of Surgical Operations. Behind them hangs a portrait of Dr. Robert M.Zollinger, Sr.

INSIDE:

2 OSU Surgeonamong first toperformprocedure

3 Dr. Higginsshares visionat townmeeting

4 Microsurgery inthe laboratory

5 Spotlight onstaff: HeidiPieper

7 Second AnnualRubergSymposium

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Surgery Today | November 2010 | 2

Advantages include

a decreased risk of

infection and less

pain.

Narula

MINIMALLY INVASIVE SURGERY

OSU Surgeon first to perform procedure

A surgical team at the Ohio State University Medical Center became one ofthe first in the nation to remove a patient’s gall bladder transvaginally. Theadvanced surgery technique decreases pain, reduces the risk of infection or asubsequent hernia, and leaves no scar.

The procedure was performed on a 42-year-old Columbus woman and is partof a pilot study leading up to the first human multi-center trial in the worldcomparing laparoscopic and transvaginal natural orifice surgery.

In 2006, Ohio State surgeons were among the first in the country to use theincisionless technology for diagnosing abdominal malignancies and cancerstaging through the mouth. The technique allowed a flexible endoscopy tubeencasing a fiber-optic camera and remote-controlled surgical cutting tool topierce the stomach wall for performing delicate surgical procedures. Thisparticular procedure has been performed in more than 120 patients at OhioState.

Dr. Vimal Narula, the surgeon who performed the first transvaginal gallbladderremoval at Ohio State, says the successful procedure shows the potential ofnatural orifice translumenal endoscopic surgery (NOTES). “OSU MedicalCenter is one of the few programs in the country with a leading role in a novelstudy to examine the use of natural orifice surgery as another emergingtechnology within the field of minimally invasive therapy,” said Narula. Thetrial is sponsored by the Natural Orifice Surgery Consortium for Assessmentand Research (NOSCAR).

Advantages to natural orifice surgery include a decreased risk of infectionand less pain, according to Narula. “Because the incision used to extract thegallbladder is located inside the body where there are no nerve endings, thereis no sensation of pain,” said Narula. “The only discomfort may come from asmall incision at the naval where a small endoscopic camera is inserted toprovide visibility to the surgeon while he uses the laparoscopic instruments.”

Other advantages to the surgery are that it reduces the risk of a hernia laterand patients have no visible scarring. Most patients can go home the sameday or the following morning.

Patients selected for the pilot procedure are carefully chosen and must beotherwise healthy and height-weight proportionate.

(OSU Medical Center Department of Strategic Communications & Marketing)

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COMPREHENSIVE TRANSPLANT CENTER

Higgins shares vision at town meeting

Dr. Robert S. D. Higgins, the John H. and Mildred C. Lumley Medical ResearchChair, professor of surgery; director, Comprehensive Transplant Center; andchief, Division of Cardiac Surgery, shared his vision for the future of OhioState’s Comprehensive Transplant Center at a recent town meeting held at theOSU Medical Center. He was introduced by Dr. Steven G. Gabbe, senior vicepresident for health sciences and CEO of the OSU Medical Center. During hisintroduction Dr. Gabbe stressed the importance of the transplant center bymentioning a patient who has survived more than 19 years post transplantand the impact that type of success has on the families of our community.

Dr. Higgins explained that the many steps of his career led him to this positionat OSU. Prior to his current appointment he was chair of the Department ofCardiovascular-Thoracic Surgery at Rush University Medical Center inChicago, Illinois. Although happy at Rush, Dr. Higgins said that he was awareof the national reputation of OSU’s transplant program and of the Ross HeartHospital. “The position at OSU seems like a good fit.” He sees an opportunityfor growth and development, saying that OSU’s transplant program has thepotential to go from a nationally recognized program to a “top 10” program.Quoting OSU president Dr. E. Gordon Gee, Higgins’ goal is to take thetransplant program “from excellence to eminence”.

Dr. Higgins listed his priorities as: 1.) reactivating the lung transplant programat OSU, and 2.) achieving critical success factors in multi-organtransplantations. Other goals include raising donor awareness andregistration, and promoting the huge impact and life-saving potential theprogram holds for the Midwest region.

The OSU Comprehensive Transplant Center is the only program of its kind inthe central Ohio area and 1 of only 254 transplant programs nationally. Over7,000 life-saving transplantations have been performed at Ohio State since theprogram’s inception in 1967.

Higgins

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Surgery Today | November 2010 | 4

RESEARCH

Microsurgery in the Laboratory: Cutting Cellsout of Tissue

Researchers can save time and money while capturing very relevant data bytaking advantage of the laser capture microdissection (LCM) technologyavailable at the Laser Capture Molecular Analysis Core. The core is directedby Dr. Sashwati Roy and managed by Dr. Sabyasachi Biswas. The core is apart of the Novel Clinical & Translational Methodologies Program, directedDr. Chandan Sen, professor of surgery.

This exciting technology was developed at the National Institute of Health toovercome the heterogeneity of tissue to isolate specific and pure populationsof cells. The LCM core utilizes a state-of-the-art PALM Microbeam systemthat features laser microdissection and pressure catapulting (LMPC). In LMPCthe biological material is placed on a polyethylene napthalate (PEN) membranecovered glass slide. The microscope-based technique locates and marks thespecific tissue to be sampled and a tightly focused laser beam is used to cutthe PEN membrane and the material. A defocused laser beam is then used to“pressure catapult” the cut membrane with cells into a sample collector. Thesystem allows for samples to be taken at the cellular level. The hugeadvantage of this technology is that a very specific tissue sample is obtained,without contamination. The speed of the process also allows for thepreservation RNA for analysis.

Researchers may obtain a $100 credit for future core use by citing “Lasercapture microdissection and subsequent analysis was performed at the LaserCapture Molecular Core of The Ohio State University Medical Center” in theMETHODS section of their manuscript. Details regarding the credit, corepolicies and fees, and for equipment training and scheduling can be found athttps://lcm.osu.edu/index.cfm. The core is located in the Biomedical ResearchTower.

Roy

Dr. Sabya Biswasdemonstrates the LCMsystem.

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SPOTLIGHT ON STAFF

Heidi Pieper

Surgery housestaff at Ohio State have a great resource and strong advocatein Heidi Pieper. Heidi is the general surgery residency coordinator for theDepartment of Surgery and her job is to help residents and fellows smoothlynavigate the Department’s programs.

At the suggestion of a friend, Heidi began working part-time in theDepartment of Surgery while an undergraduate at OSU. After graduating in2004 with a Bachelor’s Degree in English education, Heidi left Ohio Statebriefly, returning in 2005 to accept her current full-time position.

Heidi coordinates many activities of the general surgery residency program,including program accreditation, housestaff credentialing, resident compliancewith requirements, didactic conferences, and managing the resident websiteand on-line curricula. She also works closely with Dr. Ginny Bumgardner,professor of surgery in the Division of Transplantation, and associate dean,Research Education & Graduate Studies, managing the Master’s of MedicalScience Program (MMSP) for the university. The majority of general surgeryresidents complete the MMSP. Heidi helps all candidates with grantapplications, manages their program requirements, advises on courseselection and acts as a program liaison with the College of Medicine.

Dr. Jon Henry, a general surgery resident currently in the MMSP, stated,“Heidi is truly integral to our success throughout the residency program andMMS degree. Her dedication to our careers allows us to concentrate on ourresearch, education, and patient care. We are truly thankful that she is here.”Dr. Tom Pham, another resident currently in the MMSP added, “Heidi isextremely vital in helping me schedule classes and fulfill all my requirements.”Dr. Laura Peterson, general surgery resident, agreed, “Heidi is very much theheart of the MMSP. She is always available to help out, not only with anyorganizational issue that may arise, but also with making sure that thestudents get the most out of their experience. We are very lucky to have herinvolvement with the program.”

Heidi said it is extremely rewarding for her to see residents graduate from theirresidencies after having worked with them so closely for the entire duration oftheir surgical training. The class of 2011 will be the first class that she hasworked with for their entire residency, from the match process throughgraduation. “I still keep in touch with many of our graduates,” she explained.

Away from work, the Brookville, Ohio native stays busy raising her 2-year-olddaughter, Isabel, with husband, Mark. She enjoys spending time with familyand friends, taking in a movie, and of course, attending OSU Buckeye footballgames.

Pieper

“Her dedication to

our careers allows

us to concentrate

on our research,

education and

patient care.”

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MASTER OF MEDICAL SCIENCE PROGRAM

Master of Medical Science Program StudentUpdates

Dr. Jon Henry received notice that his application to the National Institutes ofHealth (NIH) Clinical Loan Repayment Program (LRP) was approved forfunding by National Cancer Institute (NCI). His research advisors are Dr.Thomas Schmittgen, associate professor in the College of Pharmacy, Dr. CarlSchmidt, assistant professor in the Division of Surgical Oncology, and Dr.Mark Bloomston, assistant professor of surgery in the Division of SurgicalOncology.

Dr. Eric Luedke has been awarded a training position on the CCC T32Oncology Training Grant for the 2010-2011 year on his project titled“Cetuximab Therapy of Pancreatic Cancer: Immune modulation with IL-21”.His research advisor is Dr. William Carson III, professor of surgery in theDivision of Surgical Oncology.

Dr. Laura Peterson presented a poster on October 12, 2010 at the 10th AnnualDavis Heart & Lung Research Institute’s Research Day on “Effects of NaturalVitamen E, Alpha-Tocotrienol, on Pial Collateral Circulation during AcuteIschemic Stroke”. Her research advisor is Dr. Cameron Rink, assistantprofessor in the Division of Vascular Diseases and Surgery.

Dr. Thomas Pham presented a poster on October 5, 2010 at the 96th AnnualClinical Congress of American College of Surgeons, Washington D.C. on “IL-4-Dependent, IgG1-Dominant Allogeneic Antibody Production Is Regulatedby CD8+ T Cells in a Transplant Model”. His research advisor is Dr. Ginny L.Bumgardner, professor of surgery in the Division of Transplantation andComprehensive Transplant Center.

Dr. Ricardo Quarrie presented a poster on October 5, 2010 at the 96th AnnualClinical Congress of American College of Surgeons, Washington D.C. on “TheParadoxical Effect of Mitochondrial Uncoupling on Membrane Potential andReactive Oxygen Species Production.” He also presented a poster on October12, 2010 at the 10th Annual Davis Heart & Lung Research Institute’s ResearchDay on “Ischemia-Reperfusion Decreases Mitochondrial Sensitivity to ProtonLeak.” Dr. Quarrie has recently received notification that 2 manuscriptsreporting his research results have been accepted for publications. Hisresearch advisor is Dr. Juan Crestanello, associate professor of surgery in the

Division of Cardiothoracic Surgery.

Henry

Luedke

Peterson

Pham

Quarrie

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PLASTIC SURGERY

Second Ruberg Symposium Bigger, Betterthan Firstby Anne Taylor, MD

The Second Annual Ruberg Symposium was held on September 9-11, 2010, atthe new home of the Division of Plastic Surgery, the Gowdy Field building.This was the second annual event to honor Dr. Robert L. Ruberg, our “not-yet-retired-ex-chief” of Plastic Surgery, and begin a new tradition for thealumni of the plastic surgery program to gather, and share their own expertise,while making and renewing friendships. It also commemorated the one yearanniversary of the opening of our new facility at Gowdy, and continuedmomentum for the OSU Division of Plastic Surgery.

The Ruberg Symposium weekend began with a reception and “State of theDivision” report from division chief, Dr. Michael J. Miller. He traced the rootsof the program, presenting a pictorial chronological history of our OSUProgram Alumni, and then gave us a glimpse of the future of plastic surgery atOSU, which includes our transition to Department status. This was followedby a short research update by our residents presenting some of their ongoingprojects.

The keynote address was delivered by Dr. Milton Armstrong, past facultymember from 1990-2000, and his remarks focused on the challenges ofproviding excellent and comprehensive hand surgery delivery in the currenthealth care environment. He noted that many plastic surgeons are steppingback from hand surgery, specifically complicated trauma cases, but that in hisexperience, a “two thumbs up” from a patient after their amputation, is rewardenough. He concluded his remarks with a recap of his medical missionarytrips to Haiti, and the personal fulfillment this has brought him.

Surgical education is on the cutting edge at the Ruberg Symposium, with thefirst live telecast of a case in the new OSU Outpatient Surgery Center on thefirst floor of our new Gowdy office building. The case was a complexsecondary bilateral breast reconstruction case. The patient had previouslyundergone radiation, and bilateral free TRAMs. Our expert breastreconstruction team, headed by Dr. Pankaj Tiwari and assisted by Dr. ErgunKocak, determined that to improve volume and symmetry, bilateral gelimplants would provide the best outcome. They demonstrated their techniqueat achieving their goals, and educated the audience with their surgical pearlsfor pocket creation, pedicle protection, implant size selection and infectionmitigation. Dr. Raphael Villalobos and Dr. Michael Miller fielded the attendeesquestions. Another live surgery will definitely be a part of next year’ssymposium.

Taylor

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The intent for the educational portion of the Ruberg Symposium is tohighlight our own alumni “rock-stars” and bring them back to our institutionto give presentations and share their expertise. And by all accounts, thissecond event was hugely successful in this regard. The didactic clinicaleducation began with a panel centered on current trends in breastreconstruction. Our alumni experts who gave presentations were Dr. EdGronka, ’92, and Dr. Micheal Vennemeyer, ’07. This panel was moderated byDr. Raphael Villalobos, ’97. The current uses of a cellular dermal matrix and theSPY operative camera were highlighted. The aesthetic considerations ofbreast reconstruction and many case examples were utilized to provide theattendees excellent continuing medical education.

Headed by Dr. Gayle Gordillo, ’99, the research effort at OSU plastic surgery isreaching new levels of excellence. Her work with the Hemangioma Clinic andComprehensive Wound Care Clinic have brought these programs newrecognition and funding. The exciting work by Alok Sutradhar, PhD ontopology design of segmental bone replacement was presented. This workhas gained worldwide recognition and was recently cited in “The Economist”and other prestigious web sites. Dr. Ergun Kocak, ’08, presented his work on“Gene Modified Flaps for the Targeted Delivery of Genes and Prodrugs”. Thispromises to be an ongoing project with huge clinical significance. Theaddition of dedicated researchers has rounded out our division, and has beeninstrumental in our transformation into a Department.

The second panel’s focus was the area that plastic surgery overlaps withophthalmology and otolaryngology. Our guest speaker from ophthalmology,Dr. Tom Mauger, educated us on the dry eye. While he thought this would be“too dry”, it was exactly the opposite, quenching the thirst for knowledge onone of the problems that presents to us the most. Dr. Steve Smith, fromOtolaryngology likewise did the same for the topic of the turbinates. Finallyour own Dr. Yongsook Suh, ’98, presented her extensive experience with theAsian eyelid. Her own series rivals that of the most published authors, and welook forward to seeing her work published soon. This excellent collaborationof the disciplines was moderated by Dr. Arthur Bing, who has been a presencewith our division for many decades. He has generously donated many hours,and medical textbooks to our library, which we have formally named the BingEducation Resource Center.

The new Federal law was the topic of the Health Care Reform Point/Counterpoint and both sides of the aisle were represented by Dr. Anne Taylor,’96, and Dr. Greg Pearson, ’06. Our guest speaker, Mr. Tim Maglione, seniordirector of advocacy, the Ohio State Medical Association, rounded out thepanel and provided details. The process by which the law passed, andspecific details regarding the independent payment advisory board,

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sustainable growth rate, physician quality reporting initiative, and mid-levelproviders, were debated and spurred lively discussion from all. We all agreedthat the roll-out of this law will be a topic of panels for many years to come.

The body contouring panelists, Dr. Steve Robinson, ’95, Dr. Susan Vasko, ’92,and Dr. Bivik Shah,’00, alumni practicing in Columbus, have vast experience inbody contouring using traditional and new modalities. Abdominal contouringusing aggressive liposuctioning is one of the newer combinations oftreatments presented by Dr. Robinson. His upper abdominal liposuctioning,and tight closures gave us all some things to consider. Dr. Vasko presentedher ongoing research on arm contouring with Smart Lipo. Her findings areintriguing and we all await her results, applauding her for doing a study on acontroversial subject. The treatment of breast ptosis, and volume depletion,after massive weight loss, were addressed by Dr. Shah, who has successfullycombined the mastopexy/augmentation and has achieved excellent results.This panel showcased the innovative surgeons and quality results of our ownalumni.

Our final panel on hand controversies, moderated by Dr. Armstrong, spannedthe age spectrum in our community from our newest hand surgeons, to themore experienced ones, including Dr. Brian Janz, Dr. Maya Spaeth, ’07, Dr.Michael Ruff and Dr. Jim Nappi, ’82. The topics also spanned the entirespectrum from pediatric hand issues, to more mature hand issues of carpel

OSU Division of Plastic Surgery faculty members Dr. Pankaj Tiwari, Dr. ErgunKocak, physician assistant Stacie Isler, PA-C, and faculty member Dr. Anne Taylorshow their school spirit. O-H-I-O!

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tunnel release, thumb arthodesis, and Henry Clines disease a.k.a. Dupytren’s.This panel concluded our weekend of outstanding education.

The social event for our second year was a casual, fun evening of comedy.The improvisational troupe of performers from The Shadowbox had all of us“in stitches” with their hilarious skits. We all enjoyed the chance to kick backand laugh together.

We are in the planning stages for next year’s Third Annual RubergSymposium, and hope that everyone will mark their calendars and plan toattend. The tentative dates are September 8-10. We are continuing to have theopening reception on Thursday evening, a full Friday educational component,with live surgery demonstrations, and half day Saturday, followed by the OSUfootball game. More details will be coming soon.

INFORMATION SYSTEMS

Email forwarding service changes

The Ohio State University is changing the way it administers OSU lastname.#user accounts. These changes affect all university affiliates with an activeOSU internet username, faculty, staff, and students, sponsored guests, andalumni and retirees who use the lifetime email forwarding service. Users will berequired to change their password to continue the email forwarding.

Users will be require to meet the new password requirements by theirbirthdate during the 2011 calendar year. For example, if a user’s birthday isFebruary 23, he/she has until 2/23/2011 to change their password. Once thepassword is changed a 90-day reset cycle begins.

Additional materials for users, helpful guides, and a list of frequently askedquestions can be found at http://buckeyesecure.osu.edu/Passwords/Passwords. For support, users should contact the IT Service Desk at (614)688-HELP (4357) or by email at [email protected].

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IN BRIEF

Dr. Ruberg presented with teaching awardDr. Robert L. Ruberg, professor of surgery and executive vice chair,Department of Surgery was presented with the Humanism in Medicine Awardon September 16. An ambassador from the Dean’s office, Dr. Linda Stone, metwith Dr. Ruberg to thank him for his dedication to teaching, his passion foreducation and his humanistic teaching style. Dr. Ruberg received a copy ofParker J. Palmer’s book, the “Courage to Teach”, and a personal message fromthe Dean’s office. He also receive a gold apple lapel pin to wear on his whitecoat.

As part of the Humanism in Medicine initiative, the College of Medicine isworking to identify and recognize faculty members that are devoted tohumanism and excellence in teaching. The College honors those outstandingteachers through ‘Courage to Teach’ recognition. The program began in late2009 and honorees are being selected on a regular basis. Other facultymembers of the Department of Surgery that have been honored to date are Dr.Mark Arnold, Dr. Alan Harzman, and Dr. Susan Moffatt-Bruce.

Dr. Robert Ruberg and Dr. Linda Stone.

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Former resident returns for re-certification

Former resident Khaled H. Mutabagani, MD, PhD, returned to The Ohio StateUniversity and Nationwide Children’s Hospital (NCH) in September to be re-certified in pediatric surgery. Dr. Mutabagani completed a residency in generalsurgery in 1996 at The Ohio State University, and a residency in pediatricsurgery at Ohio State and Nationwide Children’s Hospital in 1998. Dr.Mutabagani is currently a pediatric surgeon at the New Jeddah Clinic Hospitalin Jeddah, Kingdom of Saudi Arabia. The Jeddah Clinic Hospital wasestablished in 1969 by his father Dr. Hamed Mutabagani. Dr. Mutabagani,senior, expanded the business with The New Jeddah Clinic Hospital in 1979,and another hospital in Medina, in 1985.

When asked of his impressions of Columbus in 2010, Dr. Mutabagani said thatalthough most of his visit was spent at either the OSU Medical Center orNationwide Children’s Hospital, he is very impressed by the amount ofdevelopment since the time of his residencies. He specifically mentioned thatRhodes Hall Auditorium, Means Hall, and Upham Hall are no longer standing,being replaced with the Ross Heart Hospital, the Davis Heart & LungResearch Institute, and the Biomedical Research Tower. He is impressed bythe new construction taking place at Nationwide Children’s Hospital. Dr.Mutabagani also stated that the level of technology in use at Ohio State hasincreased significantly. Still, he misses the many green fields that were aroundthe university hospital in the 90s.

Dr. Mutabagani said the City of Columbus has also grown. A soccer fan, hesaid the Columbus Crew soccer team was just beginning when he lived here,and made Columbus life much more interesting for him. He likes the multi-cultural aspects of Columbus as well, and the warm friendly behavior of itsresidents toward foreigners, especially students. “Columbus maintains a nice,welcoming culture to foreign people.” Dr. Mutabagani said the OSU FootballTeam’s recent seasons are much better than when he lived in Columbus.

While in Columbus Dr. Mutabagani was able to catch-up with peers from histime as a resident, Dr. Gayle Gordillo, associate professor of surgery, PlasticSurgery, and Dr. Peter Muscarella, II, associate professor of surgery, Generaland Gastrointestinal Surgery. He also had time to visit with his formerprofessors, Dr. Mitchell Henry, professor of surgery and chief, Dr. ElmahdiElkhammas, professor of clinical surgery, and Dr. Elizabeth Ann Davies,assistant professor of surgery, Division of Transplantation; Dr. W. ScottMelvin, professor and chief, and Dr. Mark Arnold, professor of clinicalsurgery, Division of General and Gastrointestinal Surgery; and Dr. WilliamSmead, professor of surgery, Division of Vascular Diseases and Surgery. Dr.

Mutabagani

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Surgery Today | November 2010 | 13

Mutabagani also mentioned that the late Dr. Michael Walker was a talentedsurgeon, a wise mentor and good friend.

Dr. Mutabagani also spent some time at NCH with his pediatric surgeryteachers, Drs. Denis King, Steven Teich, Gail Besner and Jonathan Groner. Healso congratulated Dr. Donna Caniano on her retirement, saying, “She will bemissed.” Dr. Mutabagani also saw Dr. Thomas Boles, who was his firstpediatric surgery teacher when he started his general surgery residency, in1989, on the Children’s pediatric surgery service. “My first day I operated withDr. Boles on a child with an inguinal hernia.” Dr. Mutabagani also rememberedDr. Ann Kosloske who taught him many things during his pediatric surgeryfellowship and the late Dr. Donald Cooney, former pediatric surgery chief atChildren’s Hospital, who helped him and supported him during his residency.

Upon completion of his re-certification, Dr. Mutabagani returned to Jeddah.

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Grants

Bloomston M, Lu L, Frankel W, Hu Z. Pelotonia Idea Grant. “OpticalCoherence Tomography Imaging of Precancerous Pancreatic Lesions.”Funding: $100,000

Crestanello J. PI: American Heart Association Great Rivers Affiliate Spring2010 Clinical Research Program 10CRP4160147. “Hybrid revascularization: acollaborative approach to coronary artery disease.” Funding: $121,000. From7/1/2010 to 6/30/2012

Moffatt-Bruce S. PI: American Heart Association. “The Role of T RegulatoryCells and Regulatory Cells in Acute Cellular Rejection.” Funding: $65,000.From 7/1/2010 to 6/30/2012

Moffatt-Bruce S, Hadley G, Sen C. National Institutes for Health/ThoracicSurgery Foundation for Research and Education. “The Role of Macrophagesin Acute Cellular Rejection.” Funding: $150,000. From 7/1/2010 to 6/30/2012

Pathasarathy S. PI: National Institutes of Health/National Center forComplementary and Alternative Medicine. “Non-pharmacological control ofatherosclerosis.” Funding: $250,000. From 7/1/2010 to 6/30/2015

Sen C. PI: U.S. Department of Health and Human Services grant in the amountof $305,000 for his study “MicroRNA Control of Wound Healing.” The awardwas announced in a letter from Mary Jo Kilroy, U.S. Representative, Ohio’s15th Congressional District.

Publications

Askegard-Giesmann J, Besner G, Fabia R, Caniano D, Preston T, Kenney B.Extracorporeal Membrane Oxygenation (ECMO) as a Life-Saving Modality inthe Treatment of Pediatric Patients with Burns and Respiratory Failure. JPediatr Surg 45:1330-1335, 2010.

Blome-Eberwein S, Johnson RM, Miller SF, Caruso DM, Jordan MH, MilnerS, Tredget EE, Sittig KM, Smith L: Hydrofiber dressing with silver for themanagement of split-thickness donor sites: A randomized evaluation of twoprotocols of care. Burns, August 2010, 36(5):666-72.

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Christensen RD, Wiedmeier SE, Baer VL, Henry E, Gerday E, Lambert DK,Burnett J, Besner GE. Antecedents of Bell Stage III Necrotizing Enterocolitis.J Perinatology. 30:54-57, 2010.

Christensen R, Gordon P, Besner G. Can We Cut the Incidence of NecrotizingEnterocolitis in Half – Today? Fetal and Pediatric Pathology 29:1-14, 2010.

Chen C-L, Mehta V, Wu D, Otabor I, El-Assal O, Feng J, Radulescu A, ZhangH-Y, Chen Y, Besner G. Intestinal Phenotype in Mice Overexpressing aHeparin-Binding EGF-like Growth Factor Transgene in Enterocytes. GrowthFactors 28:82-97, 2010.

Christoforidis GA, Rink C, Kontzialis MS, Mohammad Y, Koch RM, AbduljalilAM, Bergdall VK, Roy S, Khanna S, Slivka AP, Knopp MV, Sen CK. AnEndovascular Canine Middle Cerebral Artery Occlusion Model for the Studyof Leptomeningeal Collateral Recruitment. Invest Radiol. 2010 Sep 17. [Epubahead of print]

Crockett A, Stawicki SP, Thomas YM, Jarvis A, Wang C, Beery PR, WhitmillML, Lindsey DE, Steinberg SM, Cook CH. Tree stands, not guns, are theMidwestern hunter’s most dangerous weapon. The American Surgeon,September 2010, 76(9):1006-1010.

Cudnik M, Newgard C, Sayre M, Steinberg S. Level I vs. Level II TraumaCenters: An Outcomes Based Assessment. J Trauma 2009, 66:1321-1326.

Cudnik M, Sayre M, Hiestand B, Steinberg S: Are all trauma centers createdequally? A statewide analysis. Acad Emerg Med 2010, 17:701-708.

Evans DC, Doraiswamy VA, Prosciak MP, Silviera M, Seamon MJ, RodriguezFunes V, Cipolla J, Wang CF, Kavuturu S, Torigian DA, Cook CH, Lindsey DE,Steinberg SM, Stawicki SP. Complications of pulmonary artery catheters: Acomprehensive clinical review. Scandinavian Journal of Surgery. 2009Dec;98(4):199-208.

Franz RW, Goodwin RB, Beery PR II, et al. Post-discharge outcomes of bluntcerebrovascular injuries. Vasc Endovasc Surg. 2010, 44(3):198-211.

Goodwin RB, Beery PR, Dorbish RJ, et al. Computed tomographicangiography vs. conventional angiography for the diagnosis of bluntcerebrovascular injury in trauma patients. J Trauma. 2009 Nov;67(5):1046-1050.

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Hendershot KM, Bollins JP, Armen SB, Thomas YM, Steinberg SM, Cook CH.Missed surgical intensive care unit billing: potential financial impact of 24/7faculty presence. J Trauma. 2009, 67:196-201.

Lee DS, Steinbaugh GE, Quarrie R, Zweier JL, Crestanello JA. IschemicPostconditioning Does Not Provide Cardioprotection from Long TermIschemic Injury in Male and Female Rat Heart Myocardium. J. Surg. Res. Inpress

Otabor I, Chen C-L, Huang G, Zhang H-Y, Velten M, Besner G. Heparin-Binding EGF-Like Growth Factor Protects the Lungs from Remote Injury AfterIntestinal Ischemia/Reperfusion. J Surg Res 163: 86-95, 2010.

Pleva MR, Mirtallo JM, Steinberg S: Hyperglycemic events in non-intensivecare unit patients receiving parenteral nutrition. Nutr Clin Pract. 2009, 24:626-34.

Pritchett CV, Levinsky NC, Ha YP, Dembe AE, Steinberg SM. Management ofacute appendicitis: The impact of CT scanning on the bottom line. JACS, 2010,210 (5):699-707.

Quarrie R, Cramer BM, Lee DS, Steinbaugh GE, Erdahl W, Pfeiffer DR, ZweierJL, Cretanello JA. Ischemic Preconditioning Decreases Mitochondrial ProtonLeak and Reactive Oxygen Species Production in the Postischemic Heart. J.Surg. Res. In press

Radulescu A, Yu X, Orvets N, Chen Y, Zhang H-Y, Besner G. Deletion of theHeparin-binding EGF-like Growth Factor Gene Increases Susceptibility toNecrotizing Enterocolitis. J Pediatr Surg 45:729-734, 2010.

Radulescu A, Zhang H-Y, Chen C-L, Chen Y, Zhou Y, Yu X, Otabor I, Olson J,Besner G. Expression Levels of Heparin-Binding EGF-Like Growth FactorAffect Intestinal Anastomotic Wound Healing. J Surg Res (EPub ahead ofprint).

Radulescu A, Zhang H-Y, Yu X, Olson J, Darbyshire A, Chen Y, Besner G.Heparin-Binding EGF-Like Overexpression in Transgenic Mice IncreasesResistance to Necrotizing Enterocolitis. J Pediatr Surg (in press)

Rink C, Roy S, Khan M, Ananth P, Kuppusamy P, Sen CK, Khanna S.Oxygen-sensitive outcomes and gene expression in acute ischemic stroke. JCereb Blood Flow Metab. 2010 Jul;30(7):1275-87. Epub 2010 Feb 10.

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Rink C, Khanna S. Significance of brain tissue oxygenation and thearachidonic acid cascade in stroke. Antioxid Redox Signal. 2010 Aug 2. [Epubahead of print]

Rink C, Khanna S. MicroRNA in Ischemic Stroke Etiology and Pathology.Physiol Genomics. 2010 Sep 14. [Epub ahead of print]

Satoskar AA, Pelletier R, Adams P, Nadasdy GM, Brodsky S, Pesavento T,Henry M, Nadasdy T. De novo thrombotic microangiopathy in renal allograftbiopsies-role of antibody-mediated rejection. Am J Transplant. 2010Aug;10(8):1804-11.

Seamon MJ, Franco MJ, Stawicki SP, Smith BP, Kulp H, Goldberg AJ, SantoraTA, Gaughan JP. Do Chronic Liver Disease Scoring Systems Predict Outcomesin Trauma Patients With Liver Disease? A Comparison of MELD and CTP. JTrauma. 2010 Sep;69(3):568-73.

Sen CK, Rink C, Khanna S. Palm oil-derived natural vitamin E alpha-tocotrienol in brain health and disease. J Am Coll Nutr. 2010 Jun;29(3Suppl):314S-323S.

Silviera M, Seamon M, Porshinsky B, Prosciak M, Doraiswamy V, Wang C,Lorenzo M, Truitt M, Biboa J, Jarvis A, Narula V, Steinberg S, Stawicki S:Complications related to endoscopic retrograde cholangiopancreatography: acomprehensive review. J Gastrointestin Liver Dis 2009, 18(1):73-82.

Smith V, Sun B, Lindsey D, Firstenberg MS. Surgical management of unusualgastrointestinal bleeding and a left ventricular assist device. InteractiveCardioVascular and Thoracic Surgery, 2010 Aug 30. [Epub ahead of print].

Starr JE. Starting a TEVAR Practice: Required Skills and InterdisciplinaryTeams. Journal of Vascular Surgery. 2010. October; 52:45S-49S

Stawicki SP, Guarnaschelli JJ, Dzenitis AJ. Cervical disc disease in geriatricpatients: A comparison study. European Journal of General Medicine. 2009,6(3):140-143.

Stawicki SP, Lindsey DE. ABSITE Corner: Aortic dissection. OPUS 12Scientist 2009, 3(2):30-34.

Stawicki S, Cook C, Gerlach A, Steinberg S, Evans D, Bloomston M, DavidoH, Lindsey D, Dillhoff M. Atrial fibrillation after esophagectomy: An indicatorof postoperative morbidity. General Thoracic and Cardiovascular Surgery.(Accepted September 2010)

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Wang CF, Cook CH, Whitmill ML, Thomas YM, Lindsey DE, Steinberg SM,Stawicki SP. Risk factors for retained surgical foreign bodies: A meta-analysis.OPUS 12 Scientist. 2009 Apr-Jun;3(2):21-27.

Wisler JW, Wisler JR, Coffey R, Miller S, The Diversity of WoundPresentation Associated with Freon Contact Frostbite Injury. JBCR,September/October 2010, 31(5):809-12.

Yu X, Radulescu A, Chen C-L, Besner G. Heparin-Binding EGF-like GrowthFactor Protects Pericytes from Injury. J Surg Research (in press).

Zhang H-Y, Radulescu A, Chen Y, Besner G. Heparin-Binding EGF-like GrowthFactor (HB-EGF) Improves Intestinal Microcirculation after HemorrhagicShock and Resuscitation in Mice. J Surg Res 2010 (EPub ahead of print).

Zhang H-Y, Radulescu R, Chen C-L, Olson J, Darbyshire A, Besner G. MiceOverexpressing the Gene for Heparin-Binding EGF-Like Growth Factor (HB-EGF) Have Increased Resistance to Hemorrhagic Shock and Resuscitation.Surgery (in press).

Zhou Y and Besner G. Heparin-Binding EGF-Like Growth Factor is aNeurotrophic Factor for PC12 Cells. Neurosignals (EPub ahead of print).

Abstracts

Adams RC, Gunter OL, Wisler JR, Peterson L, Whitmill ML, Cipolla J, HoeyBA, Stehly C, Steinberg SM, Cook CH, Stawicki SP. Dynamic F/Vt ratioidentifies liberation failures in patients on prolonged mechanical ventilationand normal pre-liberation F/Vt values. Am. J. Respir. Crit. Care Med., 2010May; 181: A3032.

Crockett A, Thomas Y, Jarvis A, Wang C, Beery P, Stawicki S, Whitmill M,Lindsey D, Steinberg S, Cook CH. Shoots and Ladders: A review of huntingrelated injuries in Central Ohio, 2009.

Eiferman D.S., Evans D.C., Cook C.H., Christy J.M., Murphy C.V., GerlachA.T., Lindsey D.E., Whitmill M.L., Beery P.R., Steinberg S.M., Stawicki S.P.Pre-injury beta blocker use does not affect the hyperdynamic response inolder trauma patients. 69th Annual Meeting of the American Association forthe Surgery of Trauma, Boston, MA, September 22-25, 2010.

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Evans DC, Cook CH, Christy JM, Murphy CV, Gerlach AT, Lindsey DE,Whitmill ML, Beery PR, Steinberg SM, Stawicki SP, Comorbidity-polypharmacy scoring may improve outcome prediction in older traumapatients. JACS, September 2010, 211(3S):S59.

Gerlach AT, Murphy CV, Stawicki SP, Cook CH. Modification of diet in renaldisease, modified Cockcroft-Gault and 24-hour urine formulas are poorpredictors of aminoglycosides in critically ill surgical patients.Pharmacotherapy. 2009;29:193e-194e.

Howard J, Gerckens J, Wang C, Jarvis A, Porshinsky B, Cook CH, WhitmillM, Lindsey D, Steinberg S, Stawicki S. Correlation of cardiac output asmeasured by arterial waveform analysis versus contiuous cardiac outputpulmonary artery catheter. Critical Care Medicine. 37(12):A94, 2009

Howard JM, Eiferman DS, Evans DC, Gerckens JS, Bahner DP, Steinberg SM,Beery PR, Whitmill ML, Cook CH, Stawicki SP, Two methods ofhemodynamic and volume status assessment in critically ill patients – a studyof disagreements. JACS, September 2010, 211(3S):S50.

Kincaid M, Thomas A, Zimmerman P, Klenerman P, Bergdall V, Hickman-DavisJ, Trgovcich J, Cook CH. Development of CD8 T-memory inflation aftercytomegalovirus infection determined by initial viral burden. J. Immunol.,2010, 184(1_MeetingAbstracts): p. 39.28

Radulescu A, Zhang H-Y, Chen C-L, Chen Y, Zhou Y, Olson J, Besner G.Expression Levels of Heparin-Binding EGF-Like Growth Factor AffectIntestinal Anastomotic Wound Healing. J Surg Res, 158:184-5, 2010.

Radulescu A, Zhang H-Y, Yu X, Olson J, Darbyshire A, Chen Y, Besner G.Heparin-binding EGF-like Growth Factor (HB-EGF) Overexpression inTransgenic Mice Increases Resistance to Necrotizing Enterocolitis. Journal ofthe American College of Surgeons, October, 2010.

Silviera ML, Seamon MJ, Porshinsky B, Prosciak MP, Doraiswamy VA, WangCF, Lorenzo M, Truitt M, Biboa J, Jarvis AM, Narula VK, Steinberg SM,Stawicki SP. Complications related to endoscopic retrogradecholangiopancreatography: A comprehensive clinical review. Journal ofGastrointestinal and Liver Diseases. 2009.

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Stawicki SP, Schuster D, Liu JF, Kamal J, Erdal S, Whitmill MS, Lindsey DE,Thomas YM, Steinberg SM, Cook CH. The use of momentum and stochasticindicators to correlate acute glucose spikes with clinical events: A novelmethod of examining glycemic variability in chronic ICU patients. SouthernMedical Journal, 2009 Dec; 102(12):E13.

Stawicki SP, Schuster D, Liu JF, Kamal J, Erdal S, Gerlach AT, Whitmill MS,Lindsey DE, Thomas YM, Murphy C, Steinberg SM, Cook CH. Theglucogram: a new quantitative tool for glycemic analysis in the surgicalintensive care unit. J Surg Res. February 2010, 158(2):378.

Presentations

Adams RC, Gunter OL, Wisler JR, Peterson L, Whitmill ML, Cipolla J, HoeyBA, Stehly C, Steinberg SM, Cook CH, Stawicki SP. Dynamic F/Vt ratioidentifies liberation failures in patients on prolonged mechanical ventilationand normal pre-liberation F/Vt Values. Poster ATS, New Orleans, LA, May 17,2010.

Aluganti C, Kwiatkowski P, Sai-Sudhakar C, Sun B, Philips A,Parthasarathy S. Early induction of biomarkers in thrombus-induced sheepmodel of congestive heart failure, 10th Annual Dorothy M. Davis Heart &Lung Research Institute Research Day, Columbus, OH, October 12, 2010.

Banerjee J, Roy S, Gnyawali S, Khanna S, Sen C. Conditional dicer deletionin adult hearts induces Mir-15b expression, mitochondrial dysfunction andoxidative stress, 10th Annual Dorothy M. Davis Heart & Lung ResearchInstitute Research Day, Columbus, OH, October 12, 2010.

Besner G. Big News for Small Intestines. Circle of Care North AmericanLeadership Conference, Atlanta, GA, May 13, 2010.

Besner G. HB-EGF as a Novel Therapeutic Strategy for NEC. InternationalNEC Webcast, hosted by Rainbow Babies Hospital and Nationwide Children’sHospital, Columbus, OH, June 17, 2010.

Besner G. HB-EGF: From Bench to Bedside, Donna A. Caniano Symposium,Columbus, OH, August 28, 2010

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Bobek D, Meyerson J, Wang J-J, Jackson H, Hadley G, Moffatt-Bruce S.Chronic cardiac allograft rejection: the potential role of macrophages and theactivation-associated transcripts, CCL17, CCL22 and IL-6, 10th AnnualDorothy M. Davis Heart & Lung Research Institute Research Day, Columbus,OH, October 12, 2010.

Chan YC, Khanna S, Roy S, Sen C. Hypoxia-sensitive Mir-200b regulatesangiogenic response of endothelial cells by targeting Ets-1, 10th AnnualDorothy M. Davis Heart & Lung Research Institute Research Day, Columbus,OH, October 12, 2010.

Chen C-L, Radulescu A, James I, Zhang H-Y, El-Assal O, Gunn J, Besner G.HB-EGF Promotes α-Defensin Secretion from Intestinal Paneth Cells.American Academy of Pediatrics, 2010 National Conference and Exhibition,San Francisco, CA, October, 2010.

Coffey R, Kulisek J, Tanda R, Chipps E. Early Recognition and Treatment ofAlcohol Withdrawal Syndrome in Burn Patients: Impact of Nursing Care andPatient Outcomes Using New Clinical Guideline, 38th Annual Eastern GreatLakes Burn Study Group, Cincinnati, OH, September 16-17, 2010.

Cook CH. Development of CD8 T-memory inflation after cytomegalovirusinfection determined by initial viral burden. Poster AAI Baltimore, MD, May 8,2010.

Cook CH. Transfusion for trauma and critical care, 31st Annual Adult andPediatric Trauma Symposium, St. Francis Trauma Institute, Tulsa, OK,September 17, 2010

Cook CH. Glycemic control in trauma and critical care, 31st Annual Adult andPediatric Trauma Symposium, St. Francis Trauma Institute, Tulsa, OK,September 17, 2010

Cui Y, Lu T, Parthasarathy S, Hao H, Luo M, Ahmed S, Kuppusamy P, Sen C,Verfaillie C, Tian J, Liu Z. Reactive oxygen species mediate ox-LDL-inducedinhibition of Oct-4 expression and endothelial differentiation of bone marrowstem cells, 10th Annual Dorothy M. Davis Heart & Lung Research InstituteResearch Day, Columbus, OH, October 12, 2010.

Das A, Sen C, Roy S. Lipid mediators in resolution of wound inflammation,10th Annual Dorothy M. Davis Heart & Lung Research Institute ResearchDay, Columbus, OH, October 12, 2010.

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Deliuliis J, Kampfrath T, Shah Z, Moffatt-Bruce S, Hadley G, Sun Q, SatoskarA, Rajagopalan. Diet-induced obesity alters innate and adaptive immune cellsof the vasceral adipose in a mouse model of insulin resistance, 10th AnnualDorothy M. Davis Heart & Lung Research Institute Research Day, Columbus,OH, October 12, 2010.

Doraiswamy VA, Stawicki SP, Kirkpatrick JN, Hayden GE, Gracias VH, DeanAJ. Cardiac Doppler examinations of E, E’, A, and A’ waves evaluatingechographic measurement biases between cardiologists and non-cardiologistintensivists. Poster presentation at the 2009 Arizona Scientific ChapterMeeting of the American College of Physicians Tucson, AZ, Sept. 26-27, 2009.Third Place Winner – Scientific Poster Competition.

Elkhammas EA. Liver Transplantation Update. Visiting Professor, CentralTripoli Hospital, Tipoli, Libya, August 4, 2010.

Evans DC, Cook CH, Christy JM, Murphy CV, Gerlach AT, Lindsey DE,Whitmill ML, Beery PR, Steinberg SM, Stawicki SP, Comorbidity-polypharmacy scoring may improve outcome prediction in older traumapatients. American College of Surgeons Clinical Congress, Washington, DC,October 4, 2010

Ganesh S, Das A, Khanna S, Gnyawali U, Parinandi N, Gordillo G, Sen C, RoyS. PGE2 mediated induction of oncostatin M production in human chronicwounds, 10th Annual Dorothy M. Davis Heart & Lung Research InstituteResearch Day, Columbus, OH, October 12, 2010.

Giles S, Besner G, Lowell W, Xiang H, Haley K. Attention DeficitHyperactivity Disorder Increases the Prevalence and Severity of Burn Injuriesin Children. 42nd Annual Meeting of the American Burn Association, Boston,MA, March 2010.

Gnyawali S, Xu R, Huang K, Huang J, Gnyawali U, Sen C. Multi-model in vivoimaging for wound tissue oxygen and perfusion, 10th Annual Dorothy M.Davis Heart & Lung Research Institute Research Day, Columbus, OH, October12, 2010.

Hazey J, Faculty instructor, Flexible Endoscopy for Surgeons, hands-onlaboratory postgraduate course, Endoscopic Dilation, American College ofSurgeons 96th Annual Clinical Congress, Washington, DC, October 3-7, 2010.

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Howard JM, Eiferman DS, Evans DC, Gerckens JS, Bahner DP, Steinberg SM,Beery PR, Whitmill ML, Cook CH, Stawicki SP, Two methods ofhemodynamic and volume status assessment in critically ill patients – a studyof disagreements. American College of Surgeons 96th Annual ClinicalCongress, Washington, DC, October 3-7, 2010.

Huang G, Besner G, Brigstock D. HB-EGF Gene Knockout Exacerbates LiverFibrosis in Mice. 15th Annual International Symposium on Cells of theHepatic Sinusoid, Pasadena, CA, August 2010. Winner – Trainee TravelAward Competition

Huang G, Besner G, Brigstock D. HB-EGF Attenuates Experimental LiverFibrosis and Reduces Hepatic Stellate Cell Activation. Annual Meeting of theAmerican Association for the Study of Liver Diseases (AASLD), Boston, MA,October 2010.

Husain S, Invited lecturer, Colonic Emergencies, Ischemic Colitis and AcuteHemorrhage, American College of Surgeons 96th Annual Clinical Congress,Washington, DC, October 3-7, 2010.

Itani K & Satiani B. The International Medical Graduate General Surgeon andhow best to encourage their contribution to answering the public need forGeneral Surgeons, presented at the General Surgery Think Tank meetingsponsored by the American Surgical Association Foundation, Chicago, IL,October 12-13, 2010.

Kamble P, Parthasarathy S. Aspirin regulates sirtuin gene expression;potential role in ATP conservation and cellular energy status, 10th AnnualDorothy M. Davis Heart & Lung Research Institute Research Day, Columbus,OH, October 12, 2010.

Khanna, S. Bioavailability of Orally Supplemented Tocotrienol in HumanTissues & Organs, 1st International Conference on Tocotrienols and ChronicDiseases. Wynn, Las Vegas, NV, July 29th, 2010.

Khanna, S. Natural Vitamin E Tocotrienol against Stroke, OSUN springseminar series, Columbus, OH, May 14, 2010

Kwiatkowski P, Aluganti-Narasimhulu C, Sai-Sudhakar C, Phillips A, He G,Sun B, Parthasarathy S. Comparison of histopathology and local geneexpression in different sheep models of acute ischemic cardiomyopathy, 10thAnnual Dorothy M. Davis Heart & Lung Research Institute Research Day,Columbus, OH, October 12, 2010.

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Lee D, Quarrie R, Pfeiffer D, Zweier J, Crestanello J. Mitochondrialdepolarization does not lead to cardioprotection during ischemicpreconditioning, 10th Annual Dorothy M. Davis Heart & Lung ResearchInstitute Research Day, Columbus, OH, October 12, 2010.

Maiseyeu A, Kampfrath T, Mihai G, Badgeley M, Modi S, Kongara M, PadtureN, Deiuliis J, Shah Z, Simonetti O, Parthasarathy S, Rajagopalan S.Nanofabrication and theranostic evaluation of novel multimodality imagingprobes for detection and therapy of inflammation in atherosclerosis, 10thAnnual Dorothy M. Davis Heart & Lung Research Institute Research Day,Columbus, OH, October 12, 2010.

Melvin WS, Invited lecturer, Endolumenal Therapy of GERD, The CurrentStatus of Endoluminal Treatments for Gastroesophageal Reflux Disease,American College of Surgeons 96th Annual Clinical Congress, Washington,DC, October 3-7, 2010.

Melvin WS, Invited lecturer, Advances in Endoscopic Surgery: Intraluminal,Transluminal, and Combined Laparoscopic-Endoscopic Approaches, TheCurrent Status of Endoluminal Treatments for Gastroesophageal RefluxDisease, American College of Surgeons 96th Annual Clinical Congress,Washington, DC, October 3-7, 2010.

Mikami D, Invited lecturer, Evolving Technologies and Procedures in Bariatricand Metabolic Surgery, Endoscopic Pouch and Anastomotic Revision,American College of Surgeons 96th Annual Clinical Congress, Washington,DC, October 3-7, 2010.

Miller SF. Advanced trauma life support course, Columbus, OH, July 31, 2009.

Miller SF. Crash and burn, EMS outreach, Adena Regional Medical Center,Chillicothe, OH, November 19, 2009.

Miller SF. Things That Go Boom, Local Heroes EMS Conference, Columbus,OH, April 23, 2010.

Miller SF, Murphy C, Coffey R, Intraosseous Access Use at Burn Centers,15th Meeting of the International Society for Burn Injuries, Istanbul, Turkey,June 21-25, 2010.

Miller SF, Luedke E, Coffey R, Electrical Burns and the Development of PostTraumatic Stress Disorder and Associated Psychological Sequelae, ARetrospective Study, 15th Meeting of the International Society for BurnInjuries, Istanbul, Turkey, June 21-25, 2010.

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Miller SF, Parks J, Harper C, Coffey R: Creating Hand ‘Gloves’ Using SilverSilicone Foam Dressing: The Parks-Harper Glove, Poster presentation at 15thMeeting of the International Society for Burn Injuries, Istanbul, Turkey, June21-25, 2010.

Miller SF, Wisler JR, Murphy C, Coffey R, Evaluation of Acute and ChronicHyperglycemia in Burn Injured Patients. 38th Annual Eastern Great LakesBurn Study Group, Cincinnati, OH, September 16-17, 2010.

Miller SF, Murphy C, Coffey R, Intraosseous Access Use at Burn Centers,38th Annual Eastern Great Lakes Burn Study Group, Cincinnati, OH,September 16-17, 2010.

Miller SF, Luedke E, Coffey R, Electrical Burns and the Development of PostTraumatic Stress Disorder and Associated Psychological Sequelae, ARetrospective Study, 38th Annual Eastern Great Lakes Burn Study Group,Cincinnati, OH, September 16-17, 2010.

Miller SF. Dermatologic Emergencies, MATCH: Multidisciplinary Advancesin the Treatment of the Critically-Ill Hospitalized Patient, Columbus, OH,September 21, 2010.

Narula V, Video Presentation, Laparoscopic Repair of Delayed TraumaticDiaphragmatic Hernia, American College of Surgeons 96th Annual ClinicalCongress, Washington, DC, October 3-7, 2010.

Odar C, Brown Kirschman K, Pelley T, Persinger A, Butz C, Besner G, Fabia R.Symptoms of Post-traumatic Stress in Young Pediatric Burn Patients and theirParents, Kansas Conference in Clinical Child and Adolescent Psychology,Kansas City, MO, October 7, 2010.

Otabor I, Besner G. Association of Academic Surgery Plenary Session OralPresentation. HB-EGF Protects the Lungs from Remote Organ Injury AfterIntestinal Ischemia/Reperfusion. 5th Annual Academic Surgical Congress,71st Annual Meeting of the Society of University Surgeons, San Antonio, TX,February 2, 2010.

Park HA, Kubicki N, Gnyawali S, Chan YC, Roy S, Khanna S, Sen C. Naturalvitamin E α-tocotrienol protects against stroke by induction of multidrugresistance-associated protein 1, 10th Annual Dorothy M. Davis Heart & LungResearch Institute Research Day, Columbus, OH, October 12, 2010.

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Peterson L, Khanna S, Christoforidis G, Irfanoglu O, Machiraju R, Sen C,Rink C. Effect of natural vitamin E, α-tocotrienol, on pial collateral circulationduring acute ischemic stroke, 10th Annual Dorothy M. Davis Heart & LungResearch Institute Research Day, Columbus, OH,, October 12, 2010.

Prosciak MP, Stawicki SP, Davido HT, Thomas YM, Lindsey DE, WhitmillML, Steinberg SM, Gerlach AT, Cook CH. Atrial fibrillation afteresophagectomy: A marker of increased morbidity and mortality. Posterpresentation at the American Thoracic Society International Conference, SanDiego, CA, May 15-20, 2009.

Porshinsky B. Care of the burn patient, Surgical Grand Rounds, Ohio StateUniversity, Columbus, OH, April 2010.

Quarrie R, Lee D, Zweier J, Crestanello J. Poster presentation, TheParadoxical Effect of Ischemia-Reperfusion on Mitochondrial MembranePotential and Reactive Oxygen Species Production. American College ofSurgeons 96th Annual Clinical Congress, Washington, DC, October 3-7, 2010.

Quarrie R, Lee D, Erdahl W, Pfeiffer D, Zweier J, Crestanello J. Ischemicpreconditioning increases mitochondrial sensitivity to proton leak leading todecreased reactive oxygen species production, 10th Annual Dorothy M. DavisHeart & Lung Research Institute Research Day, Columbus, OH, October 12,2010.

Radulescu A, Zhang H-Y, Chen C-L, Chen Y, Zhou Y, Yu X, Otabor I, Olson J,Besner G. Expression Levels of Heparin-Binding EGF-Like Growth FactorAffect Intestinal Anastomotic Wound Healing. 5th Annual Academic SurgicalCongress, 71st Annual Meeting of the Society of University Surgeons, SanAntonio, TX, February 2, 2010.

Radulescu A, Zhang H-Y, Yu X, Olson J, Darbyshire A, Chen Y, Besner G. HB-EGF Overexpression in Transgenuc Mice Increases Resistance to NecrotizingEnterocolitis. American College of Surgeons Surgical Forum, San Francisco,CA, October 3, 2010.

Ravi Y, Selvendiran K, Rivera B, Meuru S, Citro L, Khan M, Trigg N, Sai-Sudhakar C, Kuppusamy P. PTEN is a key mediator of vascular remodeling inpulmonary hypertension, 10th Annual Dorothy M. Davis Heart & LungResearch Institute Research Day, Columbus, OH, October 12, 2010.

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Renton D, Video presentation, Interesting and Unusual Problems in Surgery,Inguinal Hernias Encountered Lateral to the Internal Ring DuringLaparoscopic Inguinal Hernia Repair, American College of Surgeons 96thAnnual Clinical Congress, Washington, DC, October 3-7, 2010.

Rink C. Preclinical studies on Tocotrienol Against Stroke, 1st InternationalConference on Tocotrienols and Chronic Diseases. Wynn, Las Vegas, NV, July29, 2010.

Rink C. The Janus Face of Oxygen Therapy in Acute Ischemic Stroke. Burke/Cornell Medical Research Institute Seminar Series. Burke/CornellRehabilitation Hospital and Research Institute, White Plains, NY, June 29,2010.

Satiani B. Special issues for International Medical Graduates, presented at theGeneral Surgery Think Tank meeting sponsored by the American SurgicalAssociation Foundation, Chicago, IL, October 12-13, 2010.

Satiani B. Locum and itinerant General Surgery, presented at the GeneralSurgery Think Tank meeting sponsored by the American Association SurgicalFoundation, Chicago, IL, October 12-13, 2010.

Stawicki SP. The use of momentum and stochastic indicators to correlateacute glucose spikes with clinical events: A novel method of examiningglycemic variability in chronic ICU patients. Poster presentation at theSouthern Medical Association Annual Scientific Assembly, Dallas, TX, Dec 3-5, 2009.

Steinberg SM. Geriatric Trauma, EMS outreach, Fairfield Medical Center,Lancaster, OH, February 17, 2010.

Steinberg SM. Trauma 101, EMS outreach, Berger Hospital, Circleville, OH,February 22, 2010.

Sundaram J, Nandave M, Parthasarathy S, Bonilla D, Singaravelu J, Sai-Sudhakar C. Circulating platelet aggregate denudes endothelium and therebyreleases endothelial cells and endothelial cell derived particles, 10th AnnualDorothy M. Davis Heart & Lung Research Institute Research Day, Columbus,OH, October 12, 2010.

Whitmill, ML. The acute abdomen, Mednet 21, The Ohio State UniversityMedical Center, Columbus, OH, October 2009.

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Zhou Y, Otabor I, Wetzl A, Besner G. Heparin-Binding EGF-Like GrowthFactor (HB-EGF) Promotes Enteric Neural Crest Cell Migration. AmericanPediatric Surgical Association, Orlando, FL, May 27, 2010.

Outreach

The OSU Burn Center held its 4th Annual Burn Survivor Family Camp August13-15, 2010 at Camp Joy in Clarksville, Ohio.

Members of the OSU Burn Team participated in the Society of Fire PreventionEngineers’ 21st Annual Burn Center Golf Outing in Columbus, Ohio, October4, 2010. Proceeds of this annual outing are used to provide medical suppliesand services for burn patients.

RecognitionsDr. Yuk Cheung Chan, post-doctoral researcher, Department of Surgery, wasselected as 1st place during the Post-Doctoral Researcher poster competition,and awarded a certificate in recognition of outstanding achievement for hispresentation “Hypoxia-Sensitive Mir-200b Regulates Angiogenic Response ofEndothelial Cells by Targeting Ets-1”, at the 10th Annual Dorothy M. DavisHeart & Lung Research Institute Research Day, Columbus, OH, October 12,2010.

Dr. Daniel S. Eiferman, assistant professor of surgery, Division of CriticalCare, Trauma, and Burn, has successfully passed the surgical critical careboard examinations, October 2010.

Dr. Alan Harzman, assistant professor of surgery-clinical, Division of Generaland Gastrointestinal Surgery, was initiated as a Fellow of the American Collegeof Surgeons at the American College of Surgeons 96th Annual ClinicalCongress, Washington, DC, October 3-7, 2010.

Abdulfatah Issak, second year medical student, was awarded a MedicalStudent Research Initiation Grant by the Research Foundation of theAmerican Society of Colon and Rectal Surgeons for his summer projectentitled Working Against the Camera. The study evaluates trainee andattending performance of laparoscopic tasks when the camera is lookingsideways or backwards with respect to the surgeon. This trial builds onprincipal investigator Dr. Alan Harzman’s previous work on learninglaparoscopic tasks.

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Dr. Pratibha Kamble, post-doctoral researcher, Department of Surgery, wasawarded for her presentation “Aspirin Regulates Sirtuin Gene Expression;Potential Role in ATP Conservation and Cellular Energy Status” at the Post-Doctoral Researcher Poster Competition, at the 10th Annual Dorothy M.Davis Heart & Lung Research Institute Research Day, Columbus, OH, October12, 2010.

Dr. W. Scott Melvin, professor of surgery and chief, Division of General andGastrointestinal Surgery, has been named editor-in-chief of SurgicalLaparoscopy & Percutaneous Techniques.

Dr. Brian Porshinsky, assistant professor of surgery, completed a proof ofconcept study on his Novel Carpal Tunnel Release Device; November, 2009.

Dr. Brian Porshinsky, assistant professor of surgery, has filed a provisionalpatent regarding his Novel Carpal Tunnel Release Device; May, 2010.

Dr. Alok Sutradhar, post-doctoral researcher, Division of Plastic Surgery wasrecognized in the July 15, 2010 issue of The Economist, in the article “The new

face of surgery – A high-tech engineering technique offers promise toreconstructive surgery.” The article was a review of Dr. Sutradhar’s study,“Topological optimization for designing patient-specific large craniofacialsegmental bone replacements.” The study explores the use of 3D computermodeling and aerospace technology to design patient-specific structures forfacial reconstruction.

Dr. Melissa Whitmill, assistant professor of clinical surgery, has beenawarded the Outstanding Teaching Contributions Award, Department ofEmergency Medicine, The Ohio State University Medical Center, 2009.

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Surgery Today is a

quarterly electronic

publication of the

Department of Surgery at

The Ohio State University

Medical Center. © 2010

Department of Surgery,

The Ohio State University

Medical Center. E-mail:

[email protected]


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