Software & Informatics Quarterly Newsletter

Q1 · Volume 1

January 2009

Our Quarterly

Newsletter is here!

We are proud to announce the first issue of our

quarterly newsletter, featuring the latest news in

Software & Informatics.

Be sure to watch for new issues coming every

quarter.

In this issue

Orion Corporation ................................... 1

New Agilent LC & 6890 GC Drivers ...... 2

EZChrom Elite / LIMS Integration ........ 2

OpenLAB ICM Service Pack .................. 3

New ChemStation B.04.01 .................... 4

OpenLAB ECM Software

Development Kit ..................................... 5

EZChrom Elite 35900E ............................ 6

New AIC Released .................................. 6

EZChrom Elite Forums ............................ 7

Orion Corporation Converting to Agilent OpenLAB

supported by Agilent personnel in Finland, Europe

and the United States.

Reporting was an area of particular interest. Orion

was using multiple applications to create their final

reports. Standard reports were done from the

CDS, but advanced reports such as dissolution

testing had to be executed in MS Excel. With this

setup, Orion had different reports in style, format

and content and working process to get the final

analytical reports was inefficient.

With the new OpenLAB Intelligence Reporter

reporting module, Orion can now get all reports in

the same format right after acquisition is

completed from a fully validated application.

Report templates for standard and advanced

reports were developed from Agilent in close

cooperation with Orion. The new OpenLAB

Intelligence Reporter saves the customer many

hours of manual interactions and reviews.

The pilot also demonstrated how OpenLAB could

work with Orion balance systems and their LIMS

application, further improving efficiencies of the

Orion sample testing workflow. Finally, the pilot

gave Orion a chance to give input on workflow

enhancements. This input has lead to an updated

release of OpenLAB ICM that was released in time

to meet the Orion implementation schedule. “The

input on workflow from the Orion team, matched

the feedback from other customers, allowing us to

provide a better solution for our OpenLAB

installed base as well as new customers”, said

Bruce von Herrmann, VP and GM of Agilent’s

Software and Informatics Division.

For more information about Agilent OpenLAB,

please visit: http://www.agilent.com/chem/openlab.

T he pharmaceuticals business of Orion

Corporation was originally seeking to

consolidate two data systems for approximately

150 Chromatographs (70% Agilent, 30% Waters).

After Agilent demonstrated the capabilities of

OpenLAB, Orion managers saw opportunities to

dramatically increase efficiencies beyond the

chromatography data systems (CDS) in their

manufacturing and R&D sites across Finland. The

result is a $1.63 million USD contract for an

OpenLAB solution to be integrated throughout the

Orion sample testing workflow. The system began

implementation in December 2008.

“The benefits of operating all our LCs on a single

data system was obvious to us through simplified

training requirements and easier protocol

development and working processes,” said Niina

Savola, CDS Project Manager Orion. Our Agilent

representative showed us that we could solve this

problem and uncover many more opportunities to

increase efficiency by addressing our labs’ business

processes.

“OpenLAB’s Instrument Control Manager (ICM)

opened the door for the discussion, but it was the

Business Process Manager (BPM) that captured the

customer’s interest: automating data handling,

information flow, the approval process and report

generation and retrieval,” said Nigel Moorhouse,

EMEA PSO Delivery Manager, Agilent.

Agilent’s Project Services Organization had

provided technical support to Orion for a number

of years, and a high level of trust grew between the

two companies. Agilent proposed a pilot OpenLAB

project in two Orion sites, so bench analysts, lab

management, IT administrators and executives

could explore the functionality and performance of

the system. The pilot was implemented and

Q1 · Volume 1· January 2009 Page 2

A gilent has refreshed the drivers for its

flagship LC modules, and the still

popular 6890 Series GC, to offer more rugged

control with improved usability. The new LC

driver offers more complete control over

currently supported LC modules and also adds

more modules to the supported instrument

list than before. The new 6890 driver also

offers more complete and tighter control over

the Agilent 6890 Series GC.

Modules like the FPD, PTV and Volatiles inlet

are now fully controlled by the system. Both

have improved graphical interfaces to

enhance the usability and have received

extremely positive feedback.

The new drivers are available for EZChrom

Elite version 3.3.1, and for OpenLAB ICM

version 3.3.2 SP1.

New Drivers Available for the Agilent LC and 6890 GC - Jon Welsh, Product Manager

T wo new resources are available to

explain the options available for

integrating EZChrom Elite with your

company’s corporate LIMS and the benefits

of doing so. The first is a white paper, titled

“Interfacing EZChrom Elite to LIMS” (5989-

9894EN). This paper explains the three main

options available for integration. It details the

ranges of integration, and the benefits gained

at each level starting at simple file based

interfacing with standard EZChrom

functionality, available tools from partners to

customer programming interfaces.

The second paper available is a

case study for LyondellBasel

(5989-9893EN). LyondellBasel

implemented a custom interface

between their LIMS and EZChrom

Elite and now realize the benefit of

6.4 man/years of labor saved

annually, along with a significant

decrease in errors on the 450,000

samples that are run per year. If you

wish to download these papers,

visit the Literature Library on the

Agilent website.

White Paper and Case Study available for EZChrom LIMS Integration - Jon Welsh, Product Manager

Q1 · Volume 1· January 2009 Page 3

L ast fall the Agilent Software &

Informatics group formed a team to

work closely with customers running

OpenLAB ICM. Based on customer feedback,

changes enhancements were made in the

software to make it better fit their workflow

of a modern chromatography laboratory. The

result of that collaboration is the release for

OpenLAB 3.3.2 Service Pack 1.

This release in November 2008, addresses

more than 45 enhancements and open issues

based on direct feedback from OpenLAB

customers. This update also enhances the

new Agilent standard instrument interface

layer to allow the use of new Agilent

instrument drivers for the 1100/1200, 7890

and 6890. These new drivers offer a

significant improvement in usability and

ruggedness to the system.

An overview of some of the enhancements:

With the service pack, the workflow of

acquiring and reprocessing multiple runs

has been enhanced to require less

interaction, less revisions, and less

documentation to review the changes to

the data over time.

More reportable items for documenting

the revision history of results.

A new feature allowing the ability to lock

down a validated method in content.

The ability to maintain the instrument

acquisition set points permanently in the

data file.

Immediate updates of any changes to a

running sequence across the network.

Plus many others.

Please contact your Agilent representative for

more information.

Read only methods in content do not need updating

New choice added to report Acquisition parameters

OpenLAB ICM Service Pack 1 Enhancements - Jon Welsh, Product Manager

Q1 · Volume 1· January 2009 Page 4

Regulatory Compliance

Together with OpenLAB ECM the new

ChemStation enables users to work in

compliance with regulations such as 21 CFR

Part 11 with:

Mandatory log-in

Central and secure data management

Full versioning of data

Session Locking

Granular user roles and privileges

Audit trails for system, methods and

results

Configurable

A gilent ChemStation is the industry

leading analytical workstation for

Agilent instrumentation, handling a wide

variety of chromatographic applications, such

as GC, LC, LC/MS, CE and CE/MS. Users in

all industries benefit from the new features in

revision B.04.01.

ChemStation B.04.01 – Get More Out of Your

ChemStation!

More means:

Seamless fit from non-regulated to

strictly regulated workflows

Enhanced workflow support better

usability & faster review

Higher Productivity, Faster Results Review

and Improved Regulatory Compliance

Highlights of this version include:

Enhanced integration with OpenLAB ECM

for central management of data, master

methods, sequence templates and users

Granular ChemStation user privileges and

roles, centrally administered in OpenLAB

ECM

Configurable regulatory compliance, incl.

full support for 21 CFR Part 11 (requires

ChemStation OpenLAB option and

OpenLAB ECM)

Getting results faster with improvements

in the data review capabilities and

general usability

Enhancements in the 7890 GC driver

Need additional information?

Get the new ChemStation Brochure :

http://www.chem.agilent.com/Library/

brochures/5989-9790EN.pdf .

For More Information

For more information please contact your

local Agilent sales representative.

An example for the improved data review functionality is the new method-independent storage of manual

integrations. The presence of annual events is clearly marked in the navigation table.

New Version of ChemStation Boosts Laboratory Productivity - Dr. Ute Bober, ChemStation Product Manager

Q1 · Volume 1· January 2009 Page 5

SDK Technical Support

For customers that require technical

assistance in the usage of the SDK

Resolution on SDK-related bugs and

defects

Access to the latest SDK updated &

maintenance releases

SDK Assistance

For customers that require minor

assistance in SDK deployment &

software development projects

Software code guidance & review by

subject matter experts

Custom Software Development

Full software development lifecycle-

driven project, managed by Agilent

Professional Services, for systems

integrations and feature extensibility,

using the SDK.

Additional Resources

Download the OpenLAB ECM SDK Datasheet:

http://www.chem.agilent.com/Library/

datasheets/Public/Agilent Software

Informatics OpenLAB ECM Software

Development Kit.pdf

For More Information

For more information on the OpenLAB ECM

SDK please contact your local Agilent sales

representative.

A gilent Software & Informatics Division

announces the availability of the

OpenLAB ECM Software Development Kit

(SDK). The SDK allows software developers to

extend the value of OpenLAB through feature

extensibility and integrations with 3rd party

products.

Extend the Value of OpenLAB Enterprise

Content Manager

The potential benefits, of leveraging OpenLAB

ECM, via the SDK include:

Consolidate data from multiple systems &

applications

Quickly search, retrieve, and modify files

from a centralized location

Ensure file synchronization between

multiple systems and applications (LIMS,

CDS & OpenLAB ECM)

A Comprehensive Developer’s Resource

The SDK is a comprehensive developer’s

resource which includes:

OpenLAB ECM API

API Developer’s Guide with instructions &

sample code

API Deployment Installer

Software Development Kit Services

Agilent’s commitment to our customers

extends beyond the core products, to offer a

range of professional services from technical

support to custom software development

projects.

Agilent OpenLAB ECM Software Development Kit (SDK) Now Available - Michael Louie, Services Product Marketing Manager

Q1 · Volume 1· January 2009 Page 6

T he 35900E Dual-Channel Interface with

Modular Input/output is now available

on EZChrom Elite v3.3.1 and v3.2.1 and is the

replacement of the SS420x. This 24 bit analog

to digital conversion module provides remote

acquisition for up to 2 independent data

channels. Designed for laboratory use, the

35900E is LAN based and works with almost

any type of analog-signal generating

chromatography detector. The 35900E can be

added to any instrument configuration or be

setup standalone. It can also work

simultaneously with SS420x A/D converter.

The 35900E integrates well in EZChrom Elite

Client/Server networks. However, limitations

apply for certain AIC models and are

summarized in the table shown below.

The SS420x is discontinued and no longer

available for purchase. Agilent intends to

maintain support of the SS420x on forward

versions of EZChrom Elite.

To request more information please contact

Cheada Lao at: cheada_lao@agilent.com

or visit the EZChrom Elite website at:

http://www.agilent.com/chem/ezchrom

For the Migration Document, click here:

http://intranet.chem.agilent.com/

workspaces/specifications/Public/056579/

Shared%20Documents/ALGOL%20Compare%

20_5990-3167EN.pdf

Table 1: AIC Support

*RC.Net instrument drivers include Agilent LC, 7890 and most future driver developments.

Agilent Instrument Control (AIC)

Model

Support (Yes/No) Ordering Considerations

8300 (Rev.A) No Customer MUST upgrade to AIC 5000 or EZServer

8500 (Rev.B) Yes - Limited One RC.NET instrument* running at any given time. If

customer requires simultaneous control of up to four

RC.Net instrument, customer MUST upgrade to AIC 5000

or EZServer

AIC 5000 Yes Require.Net Framework 3.0 installation & AIC Image

Update.

EZServers Yes Review Hardware Requirement Documents

EZChrom Elite Now Supports the 35900E A/D - Cheada Lao, EZChrom Elite Product Manager

The new AIC models numbers are G6768AA

for EZChrom Elite and G6769AA for OpenLAB

ICM. Equipped with a faster 2.33GHz Core

Duo processor and 2 Gbytes of Ram, the

enhanced Agilent instrument drivers. The

new AIC models allow any needed

modifications, such as virus protection, to be

added to support corporate IT standards.

B ased on customer feedback, a new

model of the Agilent Instrument

Controller (AIC) was introduced last

November. This newest AIC model replaces

the currently shipping AIC5000 and is based

on the standard bundle PC shipped with all

Agilent software and offers improved

performance needed by newer instrument

drivers. Being based on a standard PC it now

offers the ability to better fit into the rigorous

standard needed by corporate IT groups.

New Model AIC Released - Jon Welsh, Product Manager

New model AIC from Agilent

Q1 · Volume 1· January 2009 Page 7

Click the following links to join:

Facebook EE Home Page:

http:www.facebook.comprofile.phpid=150774

3427&hiq=ezchrom,elite&refurl=http://

www.facebook.com/s.php?

q=ezchrom+elite&init=q

Facebook EE User’s Group:

http ://www.facebook.com/group.php?

gid=28548084002

Yahoo Work Group EE Home Page:

http://groups.yahoo.com/group/

ezchromeliteusers

A n EZChrom Elite 3.3.1 users’ forum has

been created on Yahoo Group and

Facebook as a public forum for EZChrom Elite

users to join and share ideas and

suggestions. Members are welcome to

collaborate with other registered EZChrom

Elite users and share their analysis strategies,

custom report ideas or templates and any tips

that might be useful to the larger community

of EZChrom Elite users. Come join us now

and share your experience!

EZChrom Elite 3.3.1 Now Open for Public Discussion on Facebook & Yahoo Work Group - Miriam Cuevas, Marketing Specialist