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7/31/2019 Term Paper on Genetic Engineering & IT Engineering by Meshkat & Nayeem_ICT_3rd Batch_1st Semester_2011
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Contents
1.Introduction
2.Definition
2.1 Definition of Genetic Engineering
2.2 Definition of IT Engineering
3. History
3.1 History Of Genetic Engineering
3.2 History Of IT Engineering
4.Literature Review
5.Discussion
6.Conclusion
7.References
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Definition of Genetic Engineering :
Genetic engineering alters the genetic makeup of an organism using
techniques that introduce heritable material prepared outside the organism
either directly into the host or into a cell that is
thenfused or hybridized with the host. This involves using recombinant
nucleic acid (DNA or RNA) techniques to form new combinations of
heritable genetic material followed by the incorporation of that material
either indirectly through a vector system or directly through micro-
injection, macro-injection and micro encapsulation techniques.Genetic
engineering does not include traditional animal andplant breeding, in vitro
fertilisation, induction of polyploidy, mutagenesis and cell fusion
techniques that do not use recombinant nucleic acids or a genetically
modified organism in the process. Cloning and stem cell research,
although not considered genetic engineering, are closely related and
genetic engineering can be used within them. Synthetic biology is an
emerging discipline that takes genetic engineering a step further by
introducing artificially synthesized genetic material from raw materials
into an organism. If genetic material from another species is added to the
host, the resulting organism is called transgenicIf genetic material from the
same species or a species that can naturally breed with the host is used the
resulting organism is called cisgenic.Genetic engineering can also be used
to remove genetic material from the target organism, creating a gene
knockout organism. In Europe genetic modification is synonymous with
genetic engineering while within the United States of America it can also
refer to conventional breeding methods. Within the scientific community,
the term genetic engineering is not commonly used; more specific termssuch as transgenic are preferred.
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Definition of IT Engineering :
We use the term information technology or IT to refer to an entire
industry. In actuality, information technology is the use of computers and
software to manage information. In some companies, this is referred to as
Management Information Services (or MIS) or simply as Information
Services (or IS). The information technology department of a large
company would be responsible for storing information, protecting
information, processing the information, transmitting the information as
necessary, and later retrieving information as necessary. This includes
the Internet, wireless networks, cell phones, and other communication
mediums. In the past few decades, information and communication
technologies have provided society with a vast array of new
communication capabilities. For example, people can communicate in real-
timewith others in different countries using technologies such as instant
messaging, voice over IP (VoIP), and video-conferencing. Social
networking websites like Facebook allow users from all over the world to
remain in contact and communicate on a regular basis. Modern
information technologies have created a "global village," in which people
can communicate with others across the world as if they were living next
door. For this reason, IT is often studied in the context of how modern
communication technologies affect society.
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A History of Genetic Engineering :
Humans have altered the genomes of species for thousands of years
through artificial selection and more recently mutagenesis. Genetic
engineering as the direct manipulation of DNA by humans outside
breeding and mutations has only existed since the 1970s.
Contrary to popular belief, the term "genetic engineering" was not first
coined by Jack Williamson in his science fiction novel Dragon's Island,
published in 1951. The term had been used previously in a journal article
in 1949.
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1980, the U.S. Supreme Court in the Diamond v. Chakrabarty case ruled
that genetically altered life could be patented. The insulin produced by
bacteria, branded humulin, was approved for release by the Food and Drug
Administration in 1982.
The first field trials of genetically engineered plants occurred in France
and the USA in 1986, tobacco plants were engineered to be resistant
to herbicides. The People’s Republic of China was the first country to
commercialize transgenic plants, introducing a virus-resistant tobacco in
1992.
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In 1994 Calgene attained approval to commercially release the Flavr
Savr tomato, a tomato engineered to have a longer shelf life. In 1994, the
European Union approved tobacco engineered to be resistant to the
herbicide bromoxynil, making it the first genetically engineered crop
commercialized in Europe.
In 1995, Bt Potato was approved safe by the Environmental Protection
Agency, making it the first pesticide producing crop to be approved in the
USA. In 2009 11 transgenic crops were grown commercially in 25
countries, the largest of which by area grown were the USA, Brazil,
Argentina, India, Canada, China, Paraguay and South Africa.
In 2010, scientists at the J. Craig Venter Institute, announced that they
had created the first synthetic bacterial genome, and added it to a cell
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containing no DNA. The resulting bacterium, namedSynthia, was the
world's first synthetic life form.
A History of Information Technology :
Four basic periods
Premechanical,
Mechanical,
Electromechanical, and
Electronic
A. The Premechanical Age: 3000 B.C. - 1450 A.D.
1. Writing and Alphabets--communication.
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1.1 First humans communicated only through speaking and picture
drawings.1.2 3000 B.C., the Sumerians in Mesopotamia (what is today southern
Iraq) devised cuniform
1.3 Around 2000 B.C., Phoenicians created symbols
1.4 The Greeks later adopted the Phoenician alphabet and addedvowels; the Romans gave the letters Latin names to create the
alphabet we use today.
2 Paper and Pens--input technologies.
2.1 Sumerians' input technology was a stylus that could scratch marks
in wet clay.
2.2 About 2600 B.C., the Egyptians write on the papyrus plant
2.3 around 100 A.D., the Chinese made paper from rags, on whichmodern-day papermaking is based.
3 Books and Libraries: Permanent Storage Devices.3.1 Religious leaders in Mesopotamia kept the earliest "books"
3.2 The Egyptians kept scrolls
3.3 Around 600 B.C., the Greeks began to fold sheets of papyrus
vertically into leaves and bind them together.
4 The First Numbering Systems.
4.1 Egyptian system: The numbers 1-9 as vertical lines, the number 10
as a U or circle, the number 100 as a coiled rope, and the number
1,000 as a lotus blossom.
4.2 The first numbering systems similar to those in use today were
invented between 100 and 200 A.D. by Hindus in India who
created a nine-digit numbering system.4.3 Around 875 A.D., the concept of zero was developed.
5 The First Calculators: The Abacus.
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One of the very first information processors.
B. The Mechanical Age: 1450 - 1840
1. The First Information Explosion.
1.1 Johann Gutenberg (Mainz, Germany) Invented the movable metal-
type printing process in 1450.
1.2 The development of book indexes and the widespread use of pagenumbers.
2. The first general purpose "computers"
2.1 Actually people who held the job title "computer: one who workswith numbers."
3. Slide Rules, the Pascaline and Leibniz's Machine.
3.1 Slide Rule.
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Early 1600s, William Oughtred, an English clergyman, invented the slide rule
3.2 The Pascaline. Invented by Blaise Pascal (1623-62).
3.3 Leibniz's Machine.
The Reckoner (Reconstruction)
4. Babbage's Engines
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4.1 The Difference Engine.
4.2 The Analytical Engine.
4.3 Augusta Ada Byron (1815-52): The first programmer
C. The Electromechanical Age: 1840 - 1940.
1. The Beginnings of Telecommunication.
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1.1 Voltaic Battery: Late 18th century.
1.2 Telegraph: Early 1800s.1.3 Morse Code: Developed in1835 by Samuel Morse & Dots and dashes.
1.4 Telephone and Radio: Alexander Graham Bell.
1.5 Followed by the discovery that electrical waves travel through space and
can produce an effect far from the point at which they originated.1.6 These two events led to the invention of the radio: Guglielmo Marconi &
1894
2. Electromechanical Computing
2.1 Herman Hollerith and IBM: Herman Hollerith (1860-1929) in 1880
Early punch cards
2.2 Mark 1.
Paper tape stored data and program instructions.
D. The Electronic Age: 1940 - Present. 1. First Tries.
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1.1 Early 1940s
1.2 Electronic vacuum tubes.
2. Eckert and Mauchly.
2.1 he First High-Speed, General-Purpose Computer Using Vacuum Tubes:
Electronic Numerical Integrator and Computer (ENIAC)
2.2 The First Stored-Program Computer(s)
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2.3 The First General-Purpose Computer for Commercial Use: Universal
Automatic Computer (UNIVAC).
3. The Four Generations of Digital Computing
3.1 The First Generation (1951-1958)
3.1.1 Vacuum tubes as their main logic elements.
3.1.2 Punch cards to input and externally store data.
3.1.3 Rotating magnetic drums for internal storage of data and programs :
Programs written in Machine language & Assembly language
3.2 The Second Generation (1959-1963)
3.2.1 Vacuum tubes replaced by transistors as main logic element: AT&T's
Bell Laboratories, in the 1940s & Crystalline mineral materials
called semiconductors could be used in the design of a device called
a transistor
3.2.2
Magnetic tape and disks began to replace punched cards as externalstorage devices.
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3.2.3 Magnetic cores (very small donut-shaped magnets that could be
polarized in one of two directions to represent data) strung on wire
within the computer became the primary internal storage technology
3.3 The Third Generation (1964-1979).
3.3.1 Individual transistors were replaced by integrated circuits.
3.3.2 Magnetic tape and disks completely replace punch cards as external
storage devices.
3.3.3 Magnetic core internal memories began to give way to a new form,
metal oxide semiconductor (MOS) memory, which, like integrated
circuits, used silicon-backed chips.
3.4 The Fourth Generation (1979- Present).
3.4.1 Large-scale and very large-scale integrated circuits (LSIs andVLSICs)
3.4.2 Fourth generation language software products : E.g., Visicalc, Lotus
1-2-3, dBase, Microsoft Word, and many others. Graphical User
Interfaces (GUI) for PCs arrive in early 1980s
3.4.3 Microprocessors that contained memory, logic, and control circuits (an
entire CPU = Central Processing Unit) on a single chip.Which allowed for home-
use personal computers or PCs, like the Apple (II and Mac) and IBM PC.
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Literature Review :
Literature Review :
If Norbert Weiner’s The Human Use of Human Beingshas accustomed us to thinkingabout both human beings and computers as “information organisms” (Galloway 106),
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the next logical step is, of course, to consider the body itself as a medium. Thus, in
Andrew Niccol’s Gattaca (1997), we have a representation of these anxieties playingout in the field of bio-informatics and genetic engineering, in which “life itself”
(Foucault) is viewed as an information technology.
According to Alex Galloway’s Protocol: Or How Control Exists After
Decentralization , a key event in this transition to an information, control society came
in Watson and Crick’s 1953 discovery of DNA. It was at this moment, Galloway
argues, that there was a confirmation of the special isomorphism between computers
and human beings, as life itself was recognized to be measurable and manipulatable
as information (Galloway 110-115). Thus, in Gattaca’s dystopian vision
of genetic engineering, human beings have become programmable by virtue of their
DNA, which has been accepted as the source code for human life. In the world of
Gattaca, this programming “determines where you can work, who you should marry,and what you are capable of achieving,” thereby reifying all human experience into a
mere effect of media; or the affordances of your bodily hardware. In Gattaca’s
biopower regime of control, there is no opportunity for resistance against your originor essential materiality, as your genes move “against the entropic force…
conserving information” (Galloway 104) of desirable traits, while eliminating those
which are undesirable (race being among the most conspicuously untouched topics
throughout the duration of the film).
In many ways, this practice of seeing human beings as computers represents both a
departure from and extension of Marshall McLuhan’s essay “Understanding Media,”
as it flattens the hierarchy of importance between subjects and objects implicit inMcLuhan’s concept “extensions of man,” but also takes as its foundational premise
the notion that the medium is the message. This is, of course, not to say that the
materiality (of human beings or computers) does not matter, but that to reduce the
message only to the object can produce some rather nefarious essentializations,
particularly when that medium is the human body.
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Discussion:
In recent years, public attention and controversy have blossomed regarding the use
and production of genetically modified organisms (GMO's) and other biotechnologies
used as agricultural inputs or produced as outputs. Two widely used examples of
genetically modified organisms used as agricultural inputs are RoundupTM tolerantcorn, soybeans, canola, and cotton and other plants that carry a gene from the bacteria
Bacillus thuringiensis (Bt). The Bt gene allows plants including corn and cotton to
produce its own insecticide. These two products of biotechnology research have been
adopted more rapidly by farmers than any other comparable technologies in
agricultural history (Fernandez-Cornejo & McBride, 2000; Riley, Hoffman, & Ash,1998). The purpose of this paper is to explore the implications of GMO and other
biotechnology and genetic engineering applications in production agriculture on thehealth and safety of workers.
This is not an article about food safety, though there are valid points and
considerations that justify the regulatory oversight related to food safety by the
United States Department of Agriculture (USDA), Food and Drug Administration
(FDA), and Environmental Protection Agency (EPA). These include potential health
effects related to product toxicity, changes in nutritional qualities, allergenicproperties, antibiotic resistance concerns, and other human health implications that
are theoretically possible when humans ingest genetically engineered products
(Donaldson & May, 1999; Frick, 1995). Nor is it the intent of this paper to explore
environmental health implications in great detail, although there are implicationsrelated to changing products and practices such as pesticide use and toxicity, tillage
practices (and water quality implications), pest resistance, and transfer of genes toother species (Cook, 1999; Wolfenbarger, 2000). In writing this paper I have tried to
be objective and unbiased. I am neither endorsing nor casting doubt on the safety or
viability of genetic modification of food products and inputs used in production
agriculture. However, the fact that little published research exists related to the
impact of GMO technology on worker safety and health suggests a need to make surethat potential risks and benefits to workers get appropriately weighed as regulatoryofficials and policy makers make decisions related to these products.
Embedded within the discussion of biotechnology and genetic engineering isinformation regarding the adoption of information technology, including the Internet
and applications of e-commerce. Information technology will continue to play a role
in the future work of professionals engaged in agricultural safety and health
intervention activities. Biotechnology and information technology are symbiotic in
terms of their potential economic impact for agricultural producers (Ackridge et al.,1997; Boehlje, 1999). The use of biotechnology and especially genetic engineering in
production agriculture stems from science's knowledge of the information encoded in
the genes of the plants and animals that farmers produce.
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Farmers who are early adopters of many new technologies tend to operate larger
farms. They are better educated. Their farms are more productive. In general, the
productive use of technology requires that producers be more adept at locating,
processing, recalling, and synthesizing information (Wojan, 2000). Likewise, theprofitable use of biotechnology depends largely on farmers and agricultural workers
possessing and using many of these same skills plus they must have timely and
accurate information related to the food production and processing supply chain.
Agricultural safety and health professionals who work with the farming and food
production industry to prevent injuries and occupational illness, will require basic
knowledge of these trends in information technology as well as biotechnology tohave maximum impact, success, and viability in the future.
Little has been published documenting the human health and safety implications for
workers who produce, handle, store, process or otherwise have contact with
genetically engineered inputs or products. There are worker health and safety
implications that result from exposure to genetically engineered inputs and outputs
themselves. In addition, there are differential exposures that result from production
practices, worker skills and knowledge needed to produce genetically modified
products or use them as inputs during the production process.
Recently published USDA - National Agricultural Statistics Service (1999) data
indicate that nearly half of all U.S. farms now have a computer, and 29% of all farms
have Internet access. More research is needed to determine the importance of the
Internet in communicating agricultural safety and health to producers. Many land-
grant universities and many other public and private institutions now have dedicated
agricultural safety and health web sites. However, a survey by Tripp, Shutske, Olson,
and Schermann (1998) of larger-scale pork producers in Minnesota and summarized
by Shutske, Schermann, Tripp, and Olson (2000) indicates that the Internet was
among the least preferred information sources of worker safety and healthinformation among the 19 listed on the producer survey. Additional research is
needed to determine if agricultural producers' opinions related to the value of
Internet-based safety and health content whether it is useful, or if their rankings have
changed, since in most regions of the country, level of Internet access among farmers
has more than doubled since this survey (USDA - National Agricultural Statistics
Service, 1999). The quantity of on-line information available to producers has also
increased dramatically.This increase in Internet usage and exponential increase in
available content is a double-edged sword. Just because farmers have access does not
necessarily mean that they are seeking out information related to farm safety andhealth.
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One trend is certain. The use of electronic commerce among agricultural producers is
increasing. Morehart and Hopkins (2000) found that 15% of the farms with Internet
access are using electronic-commerce to purchase farm inputs and sell products. A
quick search of the Internet using "Google," a widely used search engine, shows 39dedicated agricultural production e-commerce sites. These range from specialty sites
that allow producers to match up unique products with buyers (such as a site that
links licorice growers to candy manufacturers) to firms that allow growers to bid ontraditional inputs like feed, fertilizer, crop chemicals, and veterinary supplies.
This trend toward increasing use of e-commerce is important because many of these
commerce web sites are being set up also as information portals or one-stop
information sources. For example, one website www.rooster.com allows customers to
purchase farm input products and supplies, but it also contains information on
commodity markets, weather forecasts, current farm news, and threaded e-mail listsallowing producers to exchange farming related knowledge and ideas. It appears that
there are many opportunities to add farming health and safety related content on a
variety of topics to these sites. Relationship building work is needed to sort out issues
of intellectual property ownership, licensing, liability, and other farm safety and
health content usage issues.Chronic disease continues to be one of the leading causes
of death and economic loss in most countries today. Hence, it has become a centralproblem for healthcare and many are looking for solutions.
Early detection and prevention of chronic disease is one of the preferred strategies forreducing the incidence of chronic disease and address escalating cost issues. It has
been widely documented that assisting chronic disease management through
information technology tends to facilitate better health outcomes. We are therefore
seeing several health IT projects being initiated and successfully supporting chronicdisease management.
This special issue aims to host a discussion and discourse on the possible applications
of IS/IT (information systems/information technology) to facilitate better chronic
disease management. ICT are a service that is spread worldwide, but not yet reachingall or not all reaching them in the same manner (Benadou, 2005), that is, here too
there is social inequality, which Castells (2002:22) has summarized in two ideas:
first, “web connection and flexibility allow connecting with that which is valuable
and reject that which is valueless, either people, companies or territories”; andsecond, “the extreme underdevelopment of technology infrastructures in most parts of
the world is an essential barrier towards development”.
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If in 2000, only 3% of the world population used the Internet, by 20071 the figure
was 16.6%. This increase is positive, but certain clarifications must be made such asIf in 2000, only 3% of the world population used the Internet, by 20071 the figure
was 16.6%. This increase is positive, but certain clarifications must be made such as
that in Canada or the United States the percentage reaches 70%, yet in most countries
in Africa it barely amounts to 4%. Or that Asia (35.6%) and Europe (28.6%) presentthe highest percentage compared to the rest of the world. Although discrimination can
be observed, for example, by gender2, since in childhood girls (76%) use computers
more than boys (71%), but in adulthood this trend is reversed (60% of women and
70% of men) due, to a great extent, to the greater family obligations for females, which condition the time available compared to men to devote to ICT.
In Spain, for example, the profile of an Internet user is male, between 35 and 36,
residing in a province capital, and only 10% access the Internet through broadband,
according to 2006 data.3 All this evidences a digital gap which, in our opinion, must
be overcome in order for the country to progress equally both internally and inrelation to other countries.
We refer to Castells and his Marshall Plan proposal for the Information Era with
various strategic recommendations such as, for example, a social economy based on
high technology for expert on-line systems on healthcare, distance education,
avoiding the bottleneck on information and technology education or preventing the
brain leak of developing countries by extending quality networks worldwide.
Conclusion: Both IT & Genetic Engineering are two basic parts of technology. Genetic
Engineering, the artificial manipulation, modification, and recombination of DNA or
other nucleic acid molecules in order to modify an organism or population of
organisms. The term genetic engineering initially meant any of a wide range of
techniques for the modification or manipulation of organisms through the processes
of heredity and reproduction. As such, the term embraced both artificial selection and
all the interventions of biomedical techniques, among them artificial insemination, in
vitro fertilization sperm banks, cloning, and gene manipulation. But the term now
denotes the narrower field of recombinant DNA technology, or gene cloning in which
DNA molecules from two or more sources are combined. IT which works for
creating global network,can help the people to give easier access in different fields of
Science & Technology including Genetic Engineering.Without the help of IT any
field of science can not be able to get world widew recognition.So we can easily said
that to achieve popularity in the whole world Genetic Engineering have no other
alternative way without taking the help of IT.
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References :
Picture- Google.com
1. The European Parliament and the council of the European Union (12 March
2001) 2. Van Eenennaam, Alison. "Is Livestock Cloning Another Form of Genetic
Engineering?". agbiotech.
3. David M. Suter, Michel Dubois-Dauphin, Karl-Heinz Krause (2006 )
4. Ernesto Andrianantoandro, Subhayu Basu, David K Kariga & Ron Weiss (16
May 2006)."Synthetic biology: new engineering rules for an emerging
discipline". Molecular Systems Biology 2 (2006.0028):
5. Jacobsen, E.; Schouten, H. J. (2008). "
6. Capecchi, M. R. (2001). "Generating mice with targeted mutations". NatureMedicine 7 (10): 1086 – 1090.
7. James H. Maryanski (October 19, 1999.)
8. http://blog.sciencefictionbiology.com/2009/04/did-science-fiction-invent-
genetic.html
9. Jackson, DA; Symons, RH; Berg, P (October 1, 1972).
10. Arnold, Paul (2009). "History of Genetics: Genetic Engineering Timeline".
11. Stanley N. Cohen and Annie C. Y. Chang (1973-05-01)
12. . Pnas.org. Retrieved 2010-07-17.
13. Jaenisch, R. and Mintz, B. (1974).
14. Goeddel, David; Dennis G. Kleid, Francisco Bolivar, Herbert L. Heyneker,
Daniel G.
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