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Thalamic Aphasia Syndrome
Teaching NeuroImages
by Umair Afzal and Muhammad U. Farooq
© 2013 American Academy of Neurology
- An 83-year-old right-handed woman presented with sudden right sided hemiparesis, somnolence and loss of normal speech.
- Speech was non-fluent with semantic paraphasias and word-finding difficulties. Word repetition and comprehension was normal.
Afzal et al.
Vignette
Afzal et al.
Figure 1
Figure 2
Afzal et al.
- MR brain showed an area of restricted diffusion in the left thalamus consistent with acute infarction.
-Speech fluency returned to normal after two days with occasional dysnomia and parapahsias.
- Left thalamic infarcts can result in aphasia which is characterized by lexical-semantic deficits and intact word repetition; fluency and comprehension are variably affected (1).
- Thalamic aphasia has been hypothesized to result from disconnection between cortical language centers and thalamic nuclei (1,2).
Teaching NeuroImages: Thalamic Aphasia Syndrome