The 37th Annual Meeting of the Japanese Society

for Biomedical Mass Spectrometry

Program

October 25th(Thu) – 26th(Fri), 2012

Aichi Industry & Labor Center (WINC AICHI), 5F Small Hall

and 6F Exhibition Space

4-38 Meieki-4, Nakamura-ku, Nagoya-city, Aichi, Japan

Akira Ishii, MD. , Ph.D.

President of the 37th Annual Meeting of

the Japanese Society for Biomedical Mass Spectrometry

Department of Legal Medicine and Bioethics

Nagoya University Graduate School of Medicine

65 Tsurumai-cho, Showa-ku, Nagoya-city, Aichi, Japan

Tel: +81-52-744-2117 Fax: +81-52-744-2121

E-mail: jsbms37@med.nagoya-u.ac.jp

mailto:jsbms37@med.nagoya-u.ac.jp

Time Schedule

October 25 (Thursday)

9:25- 9:30 Opening Remarks

9:30- 11:30 Symposium 1

11:40- 12:20 Luncheon Seminar / Board Meeting

12:20- 12:50 JSBMS General Meeting

13:00- 14:00 Poster Presentation

14:00- 15:00 Oral Session 1

15:10- 17:10 Symposium 2

17:30- 19:30 Banquet

October 26 (Friday)

9:10-10:40 Symposium 3

10:50-11:50 Invited lecture

12:00-12:40 Luncheon Seminar

12:50-13:20 Isamu Matsumoto” Prize lecture

13:20-14:40 Oral Session 2

14:50-15:50 Technical workshop1

15:50-16:35 Technical workshop2

16:35 Closing Remarks

Program

September 25(Thursday)

9:25- 9:30 Opening Remarks (Akira Ishii)

9:30- 11:30 Symposium 1

Organizer: Fumio Nomura (Chiba University),

Toyofumi Nakanishi (Osaka Medical College)

S1-1 The ”ABC” of proteomics focused on post-translational modifications.

Naoshi Dohmae1

1RIKEN Advanced Science Institute

S1-2 Identifications of amyloidogenic proteins in FFPE tissue sections of

amyloidoses and traceabilities of drugs/medicine histories in sliced hair

sections by MALDI-imaging

Toyofumi Nakanishi

Department of Clinical and Laboratory Medicine, Osaka Medical College

S1-3 Quantitative proteomics of serum for diagnostic applications.

Mamoru Satoh1,2,4

, Yusuke Kawashima3, Kazuyuki Sogawa

1,2, Tatsuya Saito

3,

Sayaka Kado4, Fumio Nomura

1,2

1Clinical Proteomics Research Center, Chiba University Hospital

2Department of Molecular Diagnosis, Graduate School of Medicine, Chiba

University 3Center for Disease Proteomics, School of Science, Kitasato University

4Chemical Analysis Center, Chiba University

S1-4 In vitro diagnostics - development to medical reimbursement

Masahiro Hashiguchi

Medical and Biologocal Laboratories Co.,LTD. Sales and Marketing

Division

11:40- 12:20 Luncheon Seminar / Board Meeting

Application of a triple quadrupole mass spectrometer on the forensic

medicine

Toshikazu Minohata (Shimadzu Corporation)

12:20- 12:50 JSBMS General Meeting

13:00- 14:00 Poster Presentation

P-1 Apolipoprotein E Serotyping

Motoi Nishimura1,2,3

, Satomi Nishimura1, Mamoru Satoh

1,3, Syoko

Kakinuma1, Kenichi Sato

2, Setsu Sawai

1,2, Sayaka Kado

4, Yoshio Kodera

3,5,

Fumio Nomura1,2,3

1Department of Molecular Diagnosis, Graduate School of Medicine, Chiba

University 2Division of Laboratory Medicine and Clinical Genetics, Chiba University

Hospital 3Clinical Proteomics Research Center, Chiba University Hospital

4Chemical Analysis Center, Chiba University

5Laboratory of Biomolecular Dynamics, Department of Physics, School of

Science, Kitasato University

P-2 Search for novel lung cancer biomarkers by proteomic analysis of

exosomal membrane

Takuya Yamashita1,2,3

, Kazuya Nagano2, So-ichiro Kanasaki

2,3, Yuka Maeda

2,3,

Hiromi Nabeshi2,3

, Tomoaki Yoshikawa2,3

,Yasuo Yoshioka2,3,4

, Masaki Inoue2,

Yasuhiro Abe2, Haruhiko Kamada

2,4, Fumiyo Kasuya

1, Yasuo

Tsutsumi2,3,4

,Shin-ichi Tsunoda2,3,4

1 Faculty of Pharmaceutical Sciences, Kobegakuin University.

2 National Institute of Biomedical Innovation.

3 Graduate School of Pharmaceutical Science, Osaka University.

4 The Center for Advanced Medical Engineering and Informatics, Osaka

University.

P-3 Calculation of O-glycosylation site occupancy based on the peak intensity

of peptide/glycopeptide ions in MALDI mass spectrum

Yoshinao Wada、Machiko Kadoya

Osaka Medical Center and Research Institute for Maternal and Child Health

P-4 Optimization of rapid identification of microorganism by

MALDI-TOFMS and its application for diagnosis of severe infectious

disease

Toyofumi Nakanishi1, Tomohiro Higashiyama

2, Yumiko Matsuyama

3,

Takayuki Takubo1

1Department of Clinical and Laboratory Medicine, Osaka Medical College

2Central Clinical Laboratory, Osaka Medical College Hospital

3Technical Support Center, Bruker Daltonics K. K.

P-5 Discrimination between methicillin-sensitive and methicillin-resistant

Staphylococcus aureus by MALDI-TOF mass spectrometry

Kazuyuki Sogawa1, Masaharu Watanabe

2, Fumie Iida

1,Syunsuke Segawa

2,

Akiko Miyabe2, Syota Murata

2, Tomoko Saito

2, and Fumio Nomura

1,2,3

1Clinical Proteomics Research Center, Chiba University Hospital

2Department of Clinical Laboratory, Chiba University Hospital

3Department of Molecular Diagnosis, Graduate School of Medicine, Chiba

University

P-6 Exploring of blood markers in early stages of chronic renal failure in rat

Toshihiro Kobayashi1, Yuriko Matsumura

1, Atsuo Iwasawa

1, Toshihiko

Ozawa1, Toshiaki Kamachi

1, Tatsuya Fujisawa

2, Kouichi Fujiwara

2, Masahiro

Kohno1, Noriaki Tanaka

2

1Tokyo Institute of Technology

2Tanaka-Kitanoda Hospital

P-7 Characterization of phase II metabolism of tetrahydrocorticosteroids in

human liver by LC/MS

Kuniko Mitamura1, Mami Kamibayashi

1, Kanta Sato

1, Sachi Fujioka

1,

Masataka Nakajima1, Rika Satoh (née Okihara)

2, Takashi Iida

2, Shigeo

Ikegawa1

1 Faculty of Pharmaceutical Sciences, Kinki University

2 College of Humanities & Sciences, Nihon University

P-8 Analysis of Steroid Hormones in Human Saliva and Serum using

Column-switching Ultra-fast LC/MS/MS

Yukiko Hirabayashi 1, Takashi Shinagawa

2, Joji Suzuki

2, Toshio Kaji

2

1 Central Research Laboratory, Hitachi, Ltd.

2 Hitachi Yokohama Hospital, Hitachi, Ltd.

P-9 TBARS does not reflect the level of phosphatidylcholine hydroperoxides

in oxidized lipoproteins

Shu-Ping Hui1, Toshihiro Sakurai

1, Shigeki Jin

1, Hirotoshi Fuda

1, Seiji

Takeda1, Takao Kurosawa

2, Hitoshi Chiba

1

1Faculty of Health Sciences, Hokkaido University, Japan

2Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido,

Japan

P-10 Simultaneous analysis of 16 plasma isoflavone metabolites in 5

age-matched young women by liquid chromatography tandem mass

spectrometry

Kaori Hosoda1, Akitomo Yokokawa

2, Hiromi Shibasaki

2, Takashi Furuta

2,

Kazuo Ishii1

1Kyorin University, School of Health Sciences

2Tokyo University of Pharmacy and Life Sciences, School of Pharmacy

P-11 Determination of pyrimidine metabolites for inborn error of pirimidine

metabolism by UPLC-MS/MS

Yasuhiro Maeda1, Ayumi Kato

1, Tetsuya Ito

2, Yoko Nakajima

2, Sayaka Kato

2,

Shinji Saito2, Kazunori Kimura

1

1 Department of Hospital Pharmacy, Graduate School of Pharmaceutical

Sciences, Nagoya City University 2

Department of Pediatrics, Graduate School of Medical Sciences, Nagoya

City University

P-12 Mass spectrometric identification of epitiostanol metabolite: In vitro

metabolism using human cryopreserved hepatocytes and human

embryonic stem cell (hESC)-derived hepatocytes, and in vivo excretion

study in human

Mitsuhiko Sato1, Masato Okano

1, Tomoharu Osada

2, Ayako Uchiyama

2, Shinji

Kageyama1

1Anti-Doping Laboratory, Mitsubishi Chemical Medience Corporation

2Advanced Medical Science Research Department, Mitsubishi Chemical

Medience Corporation

P-13 Analysis of metabolites in body fluid by gas chromatography-tandem

mass spectrometry

Shuichi Kawana1, Katsuhiro Nakagawa

1, Haruhiko Miyagawa

1, Yuki

Hasegawa2 and Seiji Yamaguchi

2

1 Analytical & Measuring Instruments Division, SHIMADZU

CORPORATION 2 Department of Pediatrics, Shimane University School of Medicine

P-14 A novel serum metabolomics-based diagnostic approach for canine

progressive myelomalacia

Maho Sumita1, Hidetaka Nishida

1,2, Reo Tamai

1, Katsuhiro Tanaka

1,

Masayuki Komori1, Masanari Nakayama

2 and Shigeo Takenaka

1

1Dept. Vet. Sci. Osaka Pref. Univ,

2Nakayama Animal Hospital.

P-15 The measurement of serum uremic toxins in chronic kidney disease

patients under conservative therapy with LC/MS/MS

Kaori Kikuchi1, Yoshiharu Itoh

1, Jun Usami

2, Tsukasa Nakamura

3, Toshimitsu

Niwa4

1Kureha Corporation

2Aichi Medical University

3Shinmatsudo Central General Hospital

4Nagoya University Graduate School of Medicine

P-16 Development of ultra high sensitive method of sphingosine-1-phosphate

by LC/MS/MS

Tomohiro Takahashi, Daisuke Saigusa, Daisuke Jinno, Asuka Inoue, Michiyo

Okutani, Junken Aoki, Naoto Suzuki, Yoshihisa Tomioka

Graduate School of Pharmaceutical Sciences, Tohoku University

P-17 Ultra-high sensitive determination analysis of sphingosine-1-phosphate in

mice brain by LC/MS/MS

Daisuke Saigusa1, Tomohiro Takahashi

1, Shiori Ootaku

1, Asuka Inoue

1,

Michiyo Okutani1, Naoto Suzuki

1, Nariyasu Mano

2, Junken Aoki

1, Yoshihisa

Tomioka1

1 Graduate School of Pharmaceutical Sciences, Tohoku University

2 Department of Pharmaceutical Sciences, Tohoku University Hospital

P-18 Direct analysis of lipid molecular species in localized areas from tissue

slices and segmented membrane by liquid extraction surface analysis

(LESA)

Ryo Taguchi1, Akinori Mizuno

1, Yoshiki Mizuno

1, Mana Yamaguchi

1 and

Kazutaka Ikeda2

1Chubu University, College of Life and Health Sciences

2Keio University, Institute for Advanced Biosciences

P-19 Analysis of prostanoids in rat brain microdialysis sample by liquid

chromatography ion trap tandem mass spectrometry

Masahiko Tachi, Fumio Kondo, Minoru Fukayama, Kazuhiro Yoshikawa,

Shoshiro Okada1

Graduate School of Medicine, Aichi Medical University

P-20 Discovery of novel therapeutic agents for inflammatory diseases via

metabolomics

Shin Nishiumi1, Yoshihiro Izumi

1, Atsuki Matubara

1, Takeshi Azuma

1,

Masaru Yoshida1

1Kobe University Graduate School of Medicine

P-21 A quantitation method of antiepileptic drugs (valproic acid and

gabapentin), in patient plasma obtained using dried blood spot, by

GC-EI-MS: Aiming at the clinical application to “micro TDM”

Kayo Ikeda1, Kazuro Ikawa

1, Yukari Imai

1, Satoko Yokoshige

1, Norifumi

Morikawa1

1Department of Clinical Pharmacotherapy, Hiroshima University

P-22 MALDI-TOF mass spectrometric determination of gold and platinum in

tissues

Kayoko Minakata1, Masako Suzuki

2, Hideki Nozawa

1, Itaru Yamagishi

1,

Kunio Gonmori1,

Koutaro Hasegawa1, Amin Wurita

1, Kanako Watanabe

1, Osamu Suzuki

1

1Department of Legal Medicine, Hamamatsu University School of Medicine

2Research Equipment Center, Hamamatsu University School of Medicine

P-23 A rapid and simultaneous analysis of melatonin receptor agonists in

human blood by ultra-performance liquid chromatography tandem mass

spectrometry

Tadashi Ogawa1, Masae Iwai

1, Hideki Hattori

1, Kenjiro Ito

1, Tetsuya Arinobu

1,

Akira Ishii2, Osamu Suzuki

3, Hiroshi Seno

1

1 Aichi Medical University School of Medicine

2 Nagoya University Graduate School of Medicine

3 Hamamatsu University School of Medicine

P-24 Metabolism of methoxyamphetamines and fluoroamphetamines by

human and mouse liver microsomes

Kazuna Miyamoto1,2

, Takuya Yamashita1, Mai Date

1, Yukiko Nakazono

3,2,

Kenji Kuwayama3, Kenji Tsujikawa

3, Yasuyoshi Miki

4, Hiroyuki Inoue

3,

http://en.wikipedia.org/wiki/Agonist

Fumiyo Kasuya1

1 Faculty of Pharmaceutical Sciences, Kobegakuin University,

2 Hitec, Inc.,

3 National Research Institute of Police Science,

4 School of Pharmaceutical

Sciences, Kinki University

P-25 A case of postmortem detected a designer drug , α -PVP and its

metabolite

Hiroshi Ochi1, Kazuo Igarashi

1,2, Takeshi Hayashi

1, Morio Iino

1

1Osaka University Graduate School of Medicine Department of Legal

Medicine, 2Association of Medicinal Analysis

P-26 Analysis of alpha-amanitin, beta-amanitin and Picrotoxin by High

Resolution and Accurate Mass LC-MS/MS

Miho Tada1, Hideki Hattori

2, Tadashi Ogawa

2, Akira Ishii

3

1 K.K. AB SCIEX,

2Aichi Medical University,

3Nagoya University Graduate

School of Medicine

P-27 Visualization of metabolite change in skeletal muscle by contraction using

imaging mass spectrometry

Naoko Goto-Inoue1, Yasuko Manabe

1, Shouta Miyatake

1, Ai Morishita

1,

Shinya Ogino1, Mitsutoshi Setou

2, Nobuharu L. Fujii

1

1Tokyo Metropolitan University

2Hamamatsu University School of Medicine

P-28 Analysis of phosphatidylcholines distribution in oral squamous cell

carcinoma by imaging mass spectrometry

Yoshiyuki Uchiyama1, Takahiro Hayasaka

2, Noritaka Masaki

2, Tetsuji Nagata

1,

Fuminori Katou1, Mitsutoshi Setou

2

1Department of Oral and Maxillofacial Surgery, Hamamatsu University

School of Medicine. 2Department of Cell Biology and Anatomy, Hamamatsu University School of

Medicine.

P-29 Imaging mass spectrometric analyses of teeth section

Hirokazu Hirano1, Takahiro Hayasaka

2, Noritaka Masaki

2, Yoshiko Watanabe

1,

Kazuma Masumoto1, Tetuji Nagata1, Fuminori Katou1 and Mitsutoshi

Setou2

1 Department of Oral and Maxillofacial surgery, Hamamatsu Univ. Sch. of

Med.

2 Department of Cell biology and anatomy, Hamamatsu Univ. Sch. of Med.

P-30 Visualization of lipid species on human retina using Mass Microscope

Takahiro Hayasaka1, Naoko Goto-Inoue

1,2, Noritaka Masaki

1, Norihiro

Ogawa3, Takeshi Kanesaka

3, Akira Hori

3, Hiroyasu Akatsu

3, Mitsutoshi

Setou1

1Hamamatsu University School of Medicine

2Tokyo Metropolitan University

3Fukushimura Hospital

P-31 Development of Mass++ : A “Platform viewer” for mass spectrometry

analysis

Shinichi Utsunomiya1, Satoshi Tanaka

1, Masaki Murase

1, Tsuyoshi Tabata

2,

Ken Aoshima2, Yoshiya Oda

2, Shigeki Kajihara

1, Koichi Tanaka

1

1 Koichi Tanaka Laboratory of Advanced Science and Technology, Shimadzu

corp. 2 Biomarkers and Personalized Medicine, Eisai Co. LTD.

14:00- 15:00 Oral Session 1

Chairperson: Kiyofumi Asai (Nagoya City University),

Kazuo Takahashi (Fujita Health University School of Medicine)

O1-1 Synthesis of galactose-deficient IgA1 O-glycans by GalNAc-transferases

expressed in IgA1-producing cells: implications for the pathogenesis of

IgA nephropathy

KazuoTakahashi1,3

, Yoshiyuki Hiki2, Yukio Yuzawa

1, Matthew B. Renfrow

3,

Jan Novak3

1Fujita Health University School of Medicine

2Fujita Health University School of Medical Science

3University of Alabama at Birmingham

O1-2 3-Deoxyglucosone trapping activity of pyridoxal 5’-phosphate as

analyzed by electrospray ionization mass spectrometry

Roumyana Mironova1, Ivaylo Ivanov

2, Valentin Lozanov

3, Silvia Russeva

3,

Svetlana Simova4, Ivan Ivanov

1, Toshimitsu Niwa

5

1Institute of Molecular Biology Roumen Tsanev, Sofia, Bulgaria

2University of Sofia St. Kliment Ohridski, Sofia,Bulgaria

3Medical University, Sofia, Bulgaria

4Institute of Organic Chemistry with Centre of Phytochemistry, Sofia,

Bulgaria

5Nagoya University Graduate School of Medicine, Nagoya, Japan

O1-3 Detection of long-acting erythropoiesis stimulating agent darbepoetin alfa

in human urine by ultra-performance liquid chromatography tandem

mass spectrometry

Masato Okano, Mitsuhiko Sato, Shinji Kageyama

Anti-Doping Laboratory, Mitsubishi Chemical Medience Corporation

O1-4 Study of relation between the effect of bezafibrate and results of in vitro

probe acylcarnitine assay in neonatal onset type of glutaric acidemia type

II

Kenji Yamada1, Hironori Kobayashi

1, Jamiyan Purevsuren

1, Tomoo

Takahashi1, Yuki Hasegawa

1, Seiji Yamaguchi

1

1Shimane University faculty of medicine

15:10- 17:10 Symposium 2

Organizer: Tetsuya Itou (Nagoya city University)

Yosuke Shigematsu (Fukui University)

S2-1 Gas chromatography/mass spectrometric measurement of organic acids

in dried blood spots for newborn screening by tandem mass spectrometry

Yosuke Shigematsu1, Ikue Hata

2

1Department of Health Science, University of Fukui

2Department of Pediatrics, University of Fukui

S2-2 Selective screening for high risk infants with metabolic disorders in

Sapporo city

Junji Hanai1, Miwa Yoshinaga

1, Yu Ota

1, Hiroo Takahashi

1, Taiko Sasaki

1,

Shosuke Nomachi2, Masayoshi Nagao

3, Mitsuru Kubota

4

1Sapporo City Institute of Public Health

2Environmental Bureau, Sapporo City

3Hokkaido Medical Center

4Saitama Childeren’s Medical Center

S2-3 Neonatal screening for inherited metabolic disorders by GC/MS using

urine samples

Takahiro Inokuchi1, Kumiko Aoki

1, Kyoko Tashiro

1, Misa Inaba

1, Kaori

Inoue1, Chihiro Yanagiuchi

1, Yuri Suzutani

1, Yoriko Watanabe

1,2, Toyojiro

Matsuishi1,2

Research Institute of Medical Mass Spectrometry, Kurume University School

of Medicine 2Department of Pediatrics and Child Health, Kurume University School of

Medicine

S2-4 Urinary organic acids analysis using GC/MS in Shimane University

Yuki OMURA-HASEGAWA, Jamiyan PUREVSUREN, Kenji YAMADA,

Tomoo TAKAHASHI, Hironori KOBAYASHI, Seiji YAMAGUCHI

Department of Pediatrics, Shimane University, School of Medicine

S2-5 Metabolic profile analysis and pathological analysis by GC/MS

Chunhua Zhang

Department of research & development of MILS International

17:30- 19:30 Banquet

September 26(Friday)

9:10-10:40 Symposium 3

Organizer: Hiroshi SENO (Aichi Medical University)

Fumio Moriya (Kawasaki University of Medical Welfare)

S3-1 Some difficulties peculiar to postmortem analysis of drugs and chemicals

Kei Yoshitome1、Satoru Miyaishi1、Fumio Moriya1,2

1 Department of Legal Medicine, Okayama University Graduate School of

Medicine, Dentistry and Pharmaceutical Sciences 2 Department of Nursing, Kawasaki University of Medical Welfare

S3-2 Development of standardized screening system in Japan for forensic

samples

Keiko Kudo, Noriaki Ikeda

Graduate School of Medical Sciences, Kyushu University

S3-3 LC/MS/MS and QTOF confirmation method of benzodiazepines in

autopsy sample

Makiko Hayashida1, Hiroko Abe

2, Masahiko Takino

3, Youkichi Ohno

1

1 Department of Legal Medicine, Nippon Medical School, Tokyo，2 MST,

Tokyo，3 Agilent Technologies, Tokyo

10:50-11:50 Invited lecture

Matsumoto and Tokyo Subway Sarin Attack from the Viewpoint of

Toxicology

Tamie Nasu1

1Chubu University

12:00-12:40 Luncheon Seminar

The Improvement of Peak Separation Capacity in Comprehensive

Measurement and Data Processing Methodology Using LC/MS

-Chromatography and Ion Mobility

Futoshi Sato

Nihon Waters K.K. Marketing Development Technology Center

12:50-13:20 Isamu Matsumoto” Prize lecture

Study on clinical application of mass spectrometry: detection and

evaluation of metabolic disorders of organic and fatty acids using GC/MS

and MS/MS

Seiji Yamaguchi

Department of Pediatrics, Shimane University School of Medicine

13:20-14:40 Oral Session 2

Chairperson: Fumio Kondo (Aichi Medical University),

Makiko Hayashida (Nippon Medical School)

O2-1 Establishment of the colorectal cancer screening system via serum

metabolome analysis

Masaru Yoshida1, Shin Nishiumi

1, Yoshihiro Izumi

1, Atsuki Matsubara

1,

Takeshi Azuma1

1Kobe University Graduate School of Medicine

O2-2 An assay of methylmalonyl-CoA-mutase by Ultra-performance liquid

chromatography tandem mass spectrometry

Tetsuya Nasu1, Yasuhiro Maeda

1, Yuji Hotta

1, Tetsuya Ito２, Yoko Nakajima

2,

Sayaka Kato2, Sinji Saito

2, Kazunori Kimura

1

1Department of Hospital Pharmacy, Graduate School of Pharmaceutical

Sciences, Nagoya City University 2Department of Pediatrics, Graduate School of Medical Sciences, Nagoya

City University

O2-3 Proteomic analysis of ligamentum flavum with hypertrophy from lumbar

spinal canal stenosis patients

Yuichiro Goda1, Takako Taniguchi

2, Nori Sato

1、Natsuo Yasui1, Hisaaki

Taniguchi2

1Department of Orthopedics, Tokushima University

2Division of Disease Proteomics, Institute for Enzyme Research, Tokushima

University

O2-4 A Systematic Approach to Avoid the Matrix Effect during

LC-ESI-MS/MS Analysis by Using Chemical Property Parameters of

Compounds

Masato Iwaya1, Ken-ichi Harada

1, 2

1Meijo University, Faculty of Pharmacy

2Meijo University, Graduate School of Environmental and Human Sciences

O2-5 Metabolomics of urine and blood plasma in rat models of drug addiction

on the basis of conditioned place preference

Kei Zaitsu1, Izuru Miyawaki

2, Tomoaki Tochitani

2, Kiyoko Bando

2, Yasushi

Horie2, Noriaki Shima

1, Munehiro Katagi

1, Michiaki Tatsuno

1, Takeshi

Bamba3, Hitoshi Tsuchihashi

4, Eiichiro Fukusaki

3

1Forensic Science Laboratory, Osaka Prefectural Police H.Q.

2Dainippon Sumitomo Pharma, Toxicology, Safety Research Laboratories

3Department of Biotechnology, Graduate School of Engineering, Osaka

University 4Department of Legal Medicine, Osaka Medical College

14:50-15:50 Technical workshop1

Chairperson: Ikai Yoshitomo (Aichi Prefectural Institute of Public Health),

WS-1 Fast and Selective Screening of Drugs in Urine using LDTD-Qq-TOF

mass spectrometry

Tetsuo Kokaji1, Miho Tada

1, Toshiyuki Yamazaki

1

1K.K AB SCIEX

WS-2 About the possibility of the DBS and other flat surface ample

( Microtome Tissue Sample, TLC Plate, Membrane, others ) analysis by

LESA ( Liquid Extraction Surface Analysis ).

Yoshiharu Naito1

1Advion Japan k.k.

WS-3 Comprehensive screening approach by LC/Q-TOFMS using exact mass

database, MSMS library and Molecular structure correlation (MSC) for

forensic toxicological samples

Masahikio Takino1, Hirokazu Sawada

1, Makiko Hayashida

2

1Agilent Technologies Japan, Ltd.

2 Department of Legal Medicine, Nippon Medical School

WS-4 LC-MS/MS analysis of drug and metabolites from Dry Blood Spot

Yasuhiko Bando1, Souki Kanda

1, Takatomo Kawamukai

1, Hiroshi Hike

2,

Amane Sakurai1

1AMR, Inc.

2Toray Research Center, Inc.

15:50-16:35 Technical workshop2

WS-5 Marker discovery research using multivariate analysis software

"SIMCA"

Shigetoshi Yoshikawa

INFOCOM CORPORATION

WS-6 Stable Isotopes in Bio Mass Spectrometry

Yoshinori Fujimine

Otsuka Pharmaceutical Co., LTD Diagnostic Division.

WS-7 The Shimadzu LC/MS product portfolio

Ichiro Hirano1, Natsuyo Asano

1, Shinjiro Fujita

1, Daisuke Okumura

2, Kazuo

Mukaibatake1

1Mass Spectrometry Business Unit, Shimadzu Corporation

16:35 Closing Remarks

The 37th Annual Meeting of the Japanese Society for Biomedical Mass

Spectrometry

President of the 37th Annual Meeting: Akira Ishii, MD. , Ph.D.

Professor, Department of Legal Medicine and Bioethics ,

Nagoya University Graduate School of Medicine,

65 Tsuruma-cho, Showa-ku, Nagoya, Aichi, 466-8550, JAPAN

Tel: +81-52-744-2117 Fax: +81-52-744-2121

E-mail: jsbms37@med.nagoya-u.ac.jp

Japanese Society for Biomedical Mass Spectrometry

President: Niwa Toshimitsu

Professor, Department of Advanced Medicine for Uremia,

65 Tsuruma-cho, Showa-ku, Nagoya, Aichi, 466-8550, JAPAN

Tel: +81-52-744-1980 Fax: +81-52-744-1954

E-mail: jsbms@med.nagoua-u.ac.jp

URL: http://www.jsbms.jp/english/

mailto:jsbms37@med.nagoya-u.ac.jphttp://www.jsbms.jp/english/