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THE ACTIVITY BALANCE OF PLATELET COLLECTION BY APHERESIS OVER A PERIOD OF 72 MONTHS (2006-2011)
AT SINGLE CENTER IN ALGERIA
R.Belhadj; R.Ahmed-nacer; M.Benakli;
N.Rahmoune; F.Mehdid; A.Talbi M.Baazizi; D.Ait-Ouali; S.Akhrouf; F.Mehenou;
RM.hamladji.
Department of Hematology and BMT unit, Pierre and Marie Curie Center, Algiers, Algeria.
INTRODUCTION
• The platelet transfusion is a surrogate therapeutic way to offset a deficit induced by disease or cytotoxic therapy.
• Platelet transfusion can be a life-saving procedure in preventing or treating serious complications from bleeding and hemorrhage in patients who have disorders manifesting as thrombocytopenia or platelet dysfunction.
• This transfusion is a necessary and constant part of hematologic reanimation.
• We present the activity balance of platelet collection in our center.
Material and methods
• Period 72 months : (2006-2011):
5548 sampling platelet concentrate units PCU (924 / year).
• Origin of donations (PCU): family + + ++ volunteers
Material and methods
Terms of sampling:
Personal qualified.Questioning.Physical examination.Laboratory study: complete blood count: rate plat ≥ 150×109/l Blood group. Viral serology: VIH, HbS, CVH, Syphilis (negative)
The platelet concentrate unit performed on a single donor thanks to a automated cell separator model TRIMA.
Material and methodsTRIMA Accel : N= 3 Agitator: N=2
• Continuous flow separator. • BV extracorporeal low.• A Better hemodynamic tolerance
•continuous Horizontal agitation.•Conservation 5-7 days.•Temperature 22 0 C
Material and methods
DISTRIBUTION BY GENDER: male predominance (93,2%)
ONLY 379 (6.8%) are femaleP50 Amiri Nadia TUNISIA:(97,5% donors is the young males)
673
14521272 1232
Material and methods
REPARTITION ACCORDING TO THE TYPE OF
DONATIONS Donations Volunteers: 512 (9.2%)
RESULTS
N = 5548Before apheresis After apheresis Loss
(%)
Hematocrit (%) (average)
41,9 (30,1 – 57,6) 40,5 (30 – 56 ) 3,34
rate plat (109 /l)(average)
262 ( 150 – 491) 163 (79 – 335) 37
BLOOD DONORS RATES BEFORE AND AFTER APHERESIS
RESULTS
N = 5548 VALUES AFTER APHERESIS
Volume deals average (ml)
3479 ( 890 – 5213)
Volume of ACDA average (ml) 314,1 (91 – 505 )
Collection volume bag average (ml) 386 (50 -647)
Plat. average yield / bag (10 11 ) 5,8 ( 1 – 8)
Duration of procedure (min) 63,71 (19 – 120 )
VALUES OF PROCEEDINGS GIFT OF PLATELET CONCENTRATE UNITS
RESULTS
Cancelled samples N = 76 (1.35%):poor donor tolerance /poor venous access
RESULTSUNITS USERS NUMBER %
STERILE UNIT (BMT/ INDUCTION CT) 3495 63
GENERAL HEMATOLOGY CENTER 1110 20
HEMATOLOGY DAY HOSPITAL / CONSULTATION
888 16
EXTRA MURAL CENTER 63 1
TOTAL 5548 100
DISTRIBUTION OF USER UNITS
RESULTS
Number of donation
Donors volunteers
AGAINST PART
BTC/ T-O (2005- 2009) 47.774 14 % 86 %
OUR CENTER ( 2006-2011) 5548 9,2 % 90,8 %
L.Ainas Revue Algérienne d’hématologie N° 5 septembre 2011: prévalence des infections VIH; VHC et Syphilis chez les donneurs de sang au CTS de (2005-2009)
COMPARISON RATES OF VOLUNTEERS DONORS IN BLOOD COMPONENT : PCU : our center / Red Blood Unit : Blood Center tranfusion (BTC) Tizi-ouzou (TO)
DISTRIBUTION OF PUC / YEAR IN ALGERIA : Multicentric study of 1 year (2009)
BTC PLATELETS SAMPLS % NUMBER OF MACHINS FOR CYTAPHERESIS
OUR CENTER 1452 54 3
UHC Oran 504 18,74 1
UHC SBA 340 12,64 2
UHC Batna 125 4,64 1
UHE Oran 119 4,42 1
Beni Messous 94 3,49 1
Tizi-Ouzou 45 1,7 1
BTC Blida 10 0,37 1
TOTAL 2689 100 11
S. Nekkal, M.Belhani .Revue Algérienne d’hématologie N° 5 septembre 2011 : la transfusion de plaquettes en hématologie: le point en 2009 Etude multicentrique
Conclusion
• The platelet transfusion is very important in hematologic reanimation.
• Despite the large number of donations (PCU) per year; it remains insufficient because of the lack of voluntary donors especially in summer and the month of Ramadan.
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