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THE CRIMINAL AND THE BENCH

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816 presence, and then he goes on to suggest many ways in which this knowledge could be increased. There are now societies of electro-encephalography in several countries and a journal will appear next year. But Jasper has found-and others in the States and in England will agree with him-that the volume and quality of original work has been disappointing. " Instead of representing.a stimulus to more intense fundamental investigation, clinical applications have drawn us away from basic research.... The outcome has been a number of pseudo-scientific clinical investiga- tions which have served only to burden editors and readers of scientific journals without providing a great attraction to more serious minded investigators con- cerned with the fundamental aspects of brain function." There appears, therefore, to be danger of criticism from two sides-the clinical and the physiological-presumably because the subject has a difficult position within both fields of work. The solution may lie in the use of a team, consisting of physicist, physiologist, and clinician, as well as the group of technicians. Such a unit would be far beyond the needs of most institutions, but it is necessary if the standard of work is to be maintained at a high level and if knowledge is to be increased. Even if most units are necessarily smaller than this, each should include a well-trained clinical worker who has knowledge of physiological method and who at least can work in close touch with academic physiologists. CEREBROVASCULAR ACCIDENTS IN HYPERTENSION THE precise nature of vascular accidents to the brain in hypertension is sometimes certain and at other times obscure. With the classical cerebral hemorrhage or thrombosis the clinical picture is usually unmistakable, and the pathogenesis beyond question. A larger group of cases is characterised by transient paralysis, paresis, aphasia, or amaurosis. Such a syndrome, now known by the generic title of hypertensive encephalopathy,l may take an acute or chronic form. Acute encephalopathy occurs with the hypertension of acute nephritis and of toxsemia of pregnancy, and with acute exacerbations of chronic hypertension. The attacks, consisting of severe headache, drowsiness, vomiting, and convulsions, may be preceded or followed by focal cerebral signs which usually leave no stigmata in those who survive. Volhard’s original suggestion that the immediate cause is acute oedema of the brain is now generally accepted ; but it is still undecided whether this oedema is due to excessive or defective arteriolar constriction. The principal features of encephalopathy in chronic hyper- tension are its brief duration and the completeness of recovery from motor or sensory disturbances ; there is, as a rule, no 10s&bgr; of consciousness. It has long been held that the disturbance is due to localised spasm of the cerebral arterioles. Pickering,2 however, now postulates that it is the outcome of embolism or thrombosis. Cerebral arteries, he points out, have exceptionally thin walls, and the media of cerebral arterioles contain relatively little muscle tissue. This anatomical evidence against contractility is supported by physiological evi- dence of difficulty in producing vasoconstriction by either adrenaline or stimulation of the cervical sympathetic fibres. Pickering draws attention to the similarity of the cerebral syndrome in hypertensive encephalopathy with that in cerebral embolism due to mitral stenosis and auricular fibrillation. In both, he suggests, the mechanism is the same--namely, sudden organic occlu- sion. In hypertensive encephalopathy the eventual state varies between complete recovery and persistent paralysis. At the latter end of the scale thrombosis or 1. Oppenheimer, B. B., Fishberg, A. N. Arch. int. Med. 1928, 41, 264. 2. Pickering, G. W. J. Amer. med. Ass. 1948, 137, 423. embolism has always been acknowledged as the cause, He believes that the termination of transient disturbances is due to dislodgement of the embolus from a main artery ; where the disturbance, though still temporary, is more protracted the embolus or thrombus may become canalised or collateral circulation develop. Pickering’s explanation-like others- is still largely based on hypothesis. But he is on firm ground in claiming that his suggestion " violates no cardinal principle in vascular physiology and is in harmony with the pathology of hypertensive disease." THE CRIMINAL AND THE BENCH " WRITE and tell him what you think of him, by all means," was the advice of an editor to a junior, and angry, member of his staff ; " but don’t send the letter." The same principle might be followed in courts of justice. Mr. Claud Mullins, giving the Maudsley lecture of the Royal Medico-Psychological Association on Nov. 12, con- sidered it a weakness of our judicial system that sentences are usually passed within a very few minutes of the verdict being reached. Judges should be beyond emotion, yet some crimes, notably sexual offences, excite unreason- able anger in many people ; and though it is unforgive- able, he said, to pass a sentence in anger, some criminals appear so unrepentant and defiant that magistrates, recorders, and even judges may be forgiven if they find them hateful. With even a smattering of psychiatric knowledge, however, judges could recognise such behaviour as a defensive reaction. The judge who forms his opinion of a prisoner by watching his conduct at the trial could hardly engage, Mr. Mullins suggested, in a more dangerous practice ; and the lawyer who says " I can tell a rogue as soon as I see him " is deceiving himself : it simply cannot be done. The rule of passing sentence directly after the verdict has another drawback : it gives the magistrate no opportunity of getting further information about the prisoner-unless, indeed, such information is obtained before the trial starts. Since the prisoner is presumed innocent until he is proved guilty this too presents difficulties. Children and young people convicted of crimes are remanded while inquiries are made ; and it might be wise to remand adult prisoners in the same way. Early in his career as a magistrate, Mr. Mullins began to have doubts about our traditional methods of dealing with criminals ; and he took the trouble to learn some- thing of abnormal psychology, and to arrange for psychiatric treatment of convicted criminals who were willing to accept it. He has even managed to persuade some who had been acquitted for lack of evidence to accept treatment. The results were encouraging, especially with some sexual offenders, notably exhibi- tionists. He realises that such patients are not necessarily cured by psychiatric treatment : but they often give up behaving in a manner which is dangerous or annoying to others and so brings them into conflict with the law. Psychiatric treatment is not necessarily an alternative to punishment, he considers ; indeed, wise punishment can satisfy a criminal’s unconscious needs, and should have his approval. Unfortunately in a high proportion of cases the punishment is related to the crime, not the criminal. The new Criminal Justice Act gives express powers to the courts to arrange for a medical inquiry into the prisoner’s case, provided he consents ; but this is a practice which has been followed in enlightened courts for a long time. Whether or not the Act will bring better conditions depends on the willingness of the courts to use their powers. Psychiatrists, he suggested, must do what they can to form a body of public opinion favouring methods more likely to induce a change of attitude in the prisoner, and hence greater protection for the public. He quoted the case of a child sent to an
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presence, and then he goes on to suggest many waysin which this knowledge could be increased. Thereare now societies of electro-encephalography in severalcountries and a journal will appear next year. But

Jasper has found-and others in the States and inEngland will agree with him-that the volume andquality of original work has been disappointing." Instead of representing.a stimulus to more intensefundamental investigation, clinical applications havedrawn us away from basic research.... The outcomehas been a number of pseudo-scientific clinical investiga-tions which have served only to burden editors andreaders of scientific journals without providing a greatattraction to more serious minded investigators con-

cerned with the fundamental aspects of brain function."There appears, therefore, to be danger of criticism fromtwo sides-the clinical and the physiological-presumablybecause the subject has a difficult position within bothfields of work. The solution may lie in the use of ateam, consisting of physicist, physiologist, and clinician,as well as the group of technicians. Such a unit wouldbe far beyond the needs of most institutions, but it isnecessary if the standard of work is to be maintainedat a high level and if knowledge is to be increased.Even if most units are necessarily smaller than this,each should include a well-trained clinical worker whohas knowledge of physiological method and who at leastcan work in close touch with academic physiologists.

CEREBROVASCULAR ACCIDENTS IN

HYPERTENSION

THE precise nature of vascular accidents to the brainin hypertension is sometimes certain and at other timesobscure. With the classical cerebral hemorrhage orthrombosis the clinical picture is usually unmistakable,and the pathogenesis beyond question. A larger groupof cases is characterised by transient paralysis, paresis,aphasia, or amaurosis. Such a syndrome, now knownby the generic title of hypertensive encephalopathy,lmay take an acute or chronic form. Acute encephalopathyoccurs with the hypertension of acute nephritis and oftoxsemia of pregnancy, and with acute exacerbationsof chronic hypertension. The attacks, consisting ofsevere headache, drowsiness, vomiting, and convulsions,may be preceded or followed by focal cerebral signswhich usually leave no stigmata in those who survive.Volhard’s original suggestion that the immediate causeis acute oedema of the brain is now generally accepted ;but it is still undecided whether this oedema is dueto excessive or defective arteriolar constriction. The

principal features of encephalopathy in chronic hyper-tension are its brief duration and the completeness ofrecovery from motor or sensory disturbances ; there is,as a rule, no 10s&bgr; of consciousness. It has long been heldthat the disturbance is due to localised spasm of thecerebral arterioles. Pickering,2 however, now postulatesthat it is the outcome of embolism or thrombosis.Cerebral arteries, he points out, have exceptionallythin walls, and the media of cerebral arterioles containrelatively little muscle tissue. This anatomical evidenceagainst contractility is supported by physiological evi-dence of difficulty in producing vasoconstriction by eitheradrenaline or stimulation of the cervical sympatheticfibres. Pickering draws attention to the similarity ofthe cerebral syndrome in hypertensive encephalopathywith that in cerebral embolism due to mitral stenosisand auricular fibrillation. In both, he suggests, themechanism is the same--namely, sudden organic occlu-sion. In hypertensive encephalopathy the eventualstate varies between complete recovery and persistentparalysis. At the latter end of the scale thrombosis or

1. Oppenheimer, B. B., Fishberg, A. N. Arch. int. Med. 1928, 41, 264.2. Pickering, G. W. J. Amer. med. Ass. 1948, 137, 423.

embolism has always been acknowledged as the cause,He believes that the termination of transient disturbancesis due to dislodgement of the embolus from a mainartery ; where the disturbance, though still temporary,is more protracted the embolus or thrombus may becomecanalised or collateral circulation develop.

Pickering’s explanation-like others- is still largelybased on hypothesis. But he is on firm ground in claimingthat his suggestion " violates no cardinal principle invascular physiology and is in harmony with the pathologyof hypertensive disease."

THE CRIMINAL AND THE BENCH

" WRITE and tell him what you think of him, by allmeans," was the advice of an editor to a junior, andangry, member of his staff ; " but don’t send the letter."The same principle might be followed in courts of justice.Mr. Claud Mullins, giving the Maudsley lecture of theRoyal Medico-Psychological Association on Nov. 12, con-sidered it a weakness of our judicial system that sentencesare usually passed within a very few minutes of theverdict being reached. Judges should be beyond emotion,yet some crimes, notably sexual offences, excite unreason-able anger in many people ; and though it is unforgive-able, he said, to pass a sentence in anger, some criminalsappear so unrepentant and defiant that magistrates,recorders, and even judges may be forgiven if they findthem hateful. With even a smattering of psychiatricknowledge, however, judges could recognise suchbehaviour as a defensive reaction. The judge who formshis opinion of a prisoner by watching his conduct at thetrial could hardly engage, Mr. Mullins suggested, in amore dangerous practice ; and the lawyer who says" I can tell a rogue as soon as I see him

" is deceivinghimself : it simply cannot be done. The rule of passingsentence directly after the verdict has another drawback :it gives the magistrate no opportunity of getting furtherinformation about the prisoner-unless, indeed, suchinformation is obtained before the trial starts. Sincethe prisoner is presumed innocent until he is provedguilty this too presents difficulties. Children and youngpeople convicted of crimes are remanded while inquiriesare made ; and it might be wise to remand adult prisonersin the same way.

Early in his career as a magistrate, Mr. Mullins beganto have doubts about our traditional methods of dealingwith criminals ; and he took the trouble to learn some-thing of abnormal psychology, and to arrange forpsychiatric treatment of convicted criminals who werewilling to accept it. He has even managed to persuadesome who had been acquitted for lack of evidenceto accept treatment. The results were encouraging,especially with some sexual offenders, notably exhibi-tionists. He realises that such patients are not necessarilycured by psychiatric treatment : but they often give upbehaving in a manner which is dangerous or annoyingto others and so brings them into conflict with the law.Psychiatric treatment is not necessarily an alternativeto punishment, he considers ; indeed, wise punishmentcan satisfy a criminal’s unconscious needs, and shouldhave his approval. Unfortunately in a high proportionof cases the punishment is related to the crime, not thecriminal. The new Criminal Justice Act gives expresspowers to the courts to arrange for a medical inquiryinto the prisoner’s case, provided he consents ; but thisis a practice which has been followed in enlightenedcourts for a long time. Whether or not the Act willbring better conditions depends on the willingness of thecourts to use their powers. Psychiatrists, he suggested,must do what they can to form a body of public opinionfavouring methods more likely to induce a change ofattitude in the prisoner, and hence greater protectionfor the public. He quoted the case of a child sent to an

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approved school for stealing, who later went to a borstalinstitution for the same offence, and still later was

repeatedly imprisoned for stealing, getting longer andlonger sentences, adding violence to theft as time wenton, and at last being dubbed in the archaic legal phrase " anincorrigible rogue." Surely such a case may be considereda failure for legal methods of treatment ; and if this iswhat such methods can do, surely psychiatrists are

entitled to demand the right to help. A body of psychia-trists investigating legal procedure might consider bettermethods of selecting magistrates, the ways in which thelaws of evidence are used to suppress facts, the ability ofjuries to decide on expert points, and the anomalousposition in which experts giving evidence are sometimesplaced. It would be better, he suggested, if experts werecalled by the court, and cross-eamined by the advocatesfor both sides, instead of being called by one side andattacked by the other. Psychiatrists who offered toinvestigate criminal procedure would naturally be muchcriticised by the lawyers ; but the large numbers of therecidivists produced under our present system wouldput them in a strong position. British legal procedurehas a high reputation for justice, but he believes it placestoo high a value on advocacy. " A trial is too much likea sporting contest, both sides observing the Queensberryrules, with the bench as referee."

ANTICONVULSANT ACTION OF INTRAVENOUS

PARALDEHYDE

PARALDEHYDE has long been used as a soporific andas an anaesthetic, but its use as an anticonvulsant isnot so widely known. In 1919 Wechsler, of New York,after trying without success many known remedies tocontrol convulsions in a hyperkinetic case of epidemicencephalitis, had recourse in desperation to intravenousparaldehyde, the effect of rectal paraldehyde havingproved merely transient, never lasting more than a

quarter of an hour. The intravenous dose-was 1 ml.,and " by the time the last drop was injected, literallybefore the needle was withdrawn, the patient quieteddown and promptly fell asleep." 1 The first injectionhaving proved successful, other injections of 1 ml. weregiven at various intervals each day for several days, andthe patient recovered without sequelse. The outcomeled Wechsler to adopt this treatment in other cases ofprotracted convulsions, including status epilepticus.His results were various, but he concluded that intra-venous paraldehyde was valuable in generalised epilepticseizures though liable to fail in convulsions due to grossorganic change in the brain-e.g., tumour, subduraliMomatoma, and dementia paralytica.The next uses of intravenous paraldehyde seem to

have been as a 2-5% solution as an anaesthetic for shortoperations 2 and in a dose of 0-1-0-2 ml. per kg. of body-weight to induce anaesthesia for longer operations inwhich anaesthesia was subsequently maintained withether.3 No further work seems to have been describeduntil the experiments on animals and clinical trials madeby de Elio and his colleagues in Madrid, which were.reported at the Dublin meeting of the Society of BritishNeurological Surgeons this year and have now beenpublished.4 4 They found by electro-encephalographythat both in the cat and in man intravenous paraldehydein doses of 0-2 ml. per kg. of body-weight either muchreduced or abolished the motor activity of the cerebralcortex. Convulsions caused by neurosurgery stimulatingthe cortex and convulsions induced with leptazol wereimmediately abolished. Intravenous paraldehyde also1. Wechsler, I. S. J. Amer. med. Ass. 1940, 114, 2198.2. Bastedo, W. A. Materia Medica, Pharmacology, Therapeutics

and Prescription Writing for Students and Practitioners.Philadelphia, 1932.

3. Nitzescu, I. I., Iacobovici, I. Pr. méd. 1934, 42, 331.4. de Elío, F. J., de Jalón, P. G., Obrador, S. Rev. clin. esp. 1948,

30, 289.

protected animals against the effect of large doses ofstrychnine. This anticonvulsant action was observedeven in decerebrate animals, spinal preparations, ganglio-nic synapses, and peripheral nerves, but its main actionwas on the cerebral cortex. In patients undergoingelectric convulsion therapy intravenous paraldehyderaised the threshold of stimulation. No toxicity wasobserved with intravenous paraldehyde given in therecommended dosage.

INSTITUTE OF OPHTHALMOLOGY

AT the formal opening of the Institute of Ophthalmo-logy on Nov. 4, a distinguished gathering, presided overby the Earl of Rothes, chairman of the board of manage-ment, listened to addresses by Sir John Parsons, F.R.S.,the "doyen of British ophthalmology, and by representa-tives of the New and Old World-Prof. Alan Woods,of the Wilmer institute of the Johns Hopkins University,and Prof. H. J. M. Weve, of the University of Utrecht.Under the direction of Sir Stewart Duke-Elder, theinstitute has been formed by pooling the resources ofthree London eye hospitals-Moorfields, the RoyalWestminster, and the Central London. The last-namednow forms the institute itself, and the beds so lost willbe made up by increasing those in the other two hospitals.The institute will have the twofold function of researchand teaching. Full-time research-workers are housedthere in well-equipped laboratories, while clinical researchwill be carried on by the segregation of special types ofeye disease and their routine examination by ophthalmicsurgeons within the building. Courses are held for theD.o.M.s., and for the F.R.c.s. in ophthalmology, includingpractical instruction in operative techniques and

laboratory methods.On the same day, at an inaugural dinner, Sir Stewart

Duke-Elder said that while the institute was not every-thing to be desired it marked a half-way house, or atleast the end of the beginning. At last there was aplace in London, away from the rush of hospital out-patients, where original work in ophthalmology couldbe done and where the scientific method could bepractised.

SPECIALIST APPOINTMENTS

STATEMENTS about the shortage of specialists are

heard with exasperation by the many young men whohave trained for specialist employment but cannotfind it. They complain that very few appointments arenow being offered, and that meanwhile they and theirfamilies can hardly make ends meet. Under the NationalHealth Service, they feel, this state of affairs shouldhave ended : the hospital boards should be advertisinga great many new posts to fill obvious deficiencies intheir service to the public ; or at least they should maketemporary appointments. But the truth is that theboards can do nothing effective of this kind until theyhave reviewed their existing staff and have decidedwhat their new establishment ought to be. The reviewhas to be completed before April 1 next, since the newcontracts are to run from that date.The Ministry of Health advises the boards to begin

by considering the proper establishment of non-specialists(house-officers, registrars, &c.). " They should thenconsider how far the services given by the presentspecialist staff need modification to provide an adequatehospital service-e.g., whether further part-time serviceor additional whole-time posts are required, whetherduties should be continued or redistributed."

" In the same way boards should consider and determinethe requirements for other medical and dental staff—e.g.,consultant advisers to regional boards ; general practi-tioners acting as medical officers of convalescent homes, &c.,or as clinical assistants ; general dental practitioners acting

1. Ministry of Health Memorandum RH 13 (48) 83, BG (48) 71.


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