The Current Investment Highlights of US National ... · The Current Investment Highlights of US...

The Current Investment Highlights of

US National Nanotechnology Initiative

Hongda Chen, Ph.D.

National Institute of Food and Agriculture (NIFA)

U.S. Department of Agriculture (USDA)

July 17, 2010, Chicago, IL

The views expressed in this presentation are those of the presenter and notnecessarily those of the United States Government or the presenter’s agency

H. Chen 7/2010 after NNCO, 4/2010Introduction to the NNI and its Investments, @ IFT 2010

Outline

What is the U.S. Government’s National

Nanotechnology Initiative (NNI)?

Overview of the NNI Budget and Investments

Potential environmental, health, and safety (EHS)

and other regulatory considerations

How can industry tap into the benefits of

nanotechnology and utilize the results of NNI-

funded research?

Education, public communication and engagement,

perception and acceptance

DHS

NRC

FDA

CPSC ITC

USPTO

NIOSH

DOC BIS

USDA

FS

DOEd

DOL

NSF

DOEDOD

NASA

NIST

NIHOMBOSTP

EPA

DOT

DOTr

DOJ

ITIC

DOS

USDA/

NIFA

National Nanotechnology Initiative

Collaborative, Multi-agency, Cross-cut

Program Among 25 Federal agencies, 15 of

which have specific nanotechnology budgets

Funds R&D to advance understanding and

control of matter at nanoscale toward:

National economic benefit

National and homeland security

Improved quality of life

USGS


The National Nanotechnology Initiative:

vision and goals

The vision of the NNI: a future in which the ability to

understand and control matter on the nanoscale leads

to a revolution in technology and industry that benefits

society

Four goals for nanoscale science, engineering, and

technology, as described in the NNI's Supplement to

the President's FY 2011 Budget and ’07 Strategic Plan:

Advance a world-class research and development program

Foster technology transfer for commercial & public benefit

Develop & sustain educational resources, a skilled workforce,

and the supporting research infrastructure and tools

Support responsible development of nanotechnology


Broad brush view of NNI operations

Management EOP + Agencies

Establishment of nanotechnology as high priority R&D area

Budget creation and funding allocation to agencies

Negotiations with Congress

Coordination NSET Subcommittee

Coordinates development of strategic plan for NNI

Providing mechanisms for interagency communication and

coordination on nanotechnology R&D

Reporting NNCO

Publishes reports on behalf of the NSET and the NNI for use

by Congress, academia, industry, and the public

Serves as central public point of contact for NNI


NNI budget information

NNI expenditures* have grown from $464 million in

FY ‘01 to an FY ‘11 request of nearly $1.8 billion.**

* All numbers shown above are actual spending, except 2010, which is estimated spendingfor the current year and 2011 , which is requested amount for next year

(FY ‘09 figure shown here does not include ~$500 million in additional ARRA funding).** 2011 figure shown here does not include DOD earmarks included in previous yrs. ($117 M ‘09)

$464

$697$760

$989

$1,200

$1,351$1,424

$1,555

$1,702$1,781 $1,762

$0

$200

$400

$600

$800

$1,000

$1,200

$1,400

$1,600

$1,800

$2,000

2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011


International nanotech R&D investment

Source: M. C. Roco, NSF

U.S. estimate for 2010 is

$1.78 billion; 2011 request

is ~$1.76 billion

New announcements from

Russia and EU recently indicate

very large new investments


NNI Support for Innovation

Cumulative NNI investment of nearly $14 billion (including the President’s request for 2011)

Advanced foundational knowledge for control of matter at the nanoscale with over 4500 research projects in all 50 states

Developed an extensive infrastructure of interdisciplinary research centers, networks and user facilities distributed across the country

Invested significantly in nanotechnology-related EHS R&D to date and anticipate continuing targeted increases

Established major networks for developing public awareness of nanotechnology and formal educational programs

Organized and conducted 16 workshops on cross-cutting areas of nanotechnology applications


NEW: Supplement to thePresident's FY 2011

Budget

NNI activities and documents inform agencies,

report outcomes, and serve as resources

General brochure for a broad

audience

NNI Strategic Plan

http://www.nano.gov/html/res/pdf/Nanotechnology_BigThingsfromaTinyWorld.pdf


NNI budget by agency, ’09-’11

* Based on allocations ARRA appropriations. Agencies may report additional ARRA funding for SBIR and STTR projects later.** 2009 and 2010 DOD figures include Congressionally directed funding that is outside the NNI plan ($117 million for 2009).

See NNI Supplement to the President’s FY ‘11 Budget for additional details: http://www.nano.gov/NNI_2011_budget_supplement.pdf.

Agency 2009 Actual 2009 Recovery* 2010 Estimated 2011 Proposed

DOE 332.6 293.2 372.9 423.9

NSF 408.6 101.2 417.7 401.3

HHS/NIH 342.8 73.4 360.6 382.4

DOD** 459.0 0.0 436.4 348.5

DOC/NIST 93.4 43.4 114.4 108.0

EPA 11.6 0.0 17.7 20.0

HHS/NIOSH 6.7 0.0 9.5 16.5

NASA 13.7 0.0 13.7 15.8

HHS/FDA 6.5 0.0 7.3 15.0

DHS 9.1 0.0 11.7 11.7

USDA/NIFA 9.9 0.0 10.4 8.9

USDA/FS 5.4 0.0 5.4 5.4

CPSC 0.2 0.0 0.2 2.2

DOT/FHWA 0.9 0.0 3.2 2.0

DOJ 1.2 0.0 0.0 0.0

TOTAL 1,701.5 511.3 1,781.1 1,761.6


USDA/NIFA Expenditure in Nanotechnology


AFRI: Nanoscale Science and Engineering

FY 2009 Priorities – Anticipated Major Changes in FY 2010

Nanoscale recognition, reception, and transmission mechanisms and novel materials for developing nano-based sensors specifically for targets important to food safety and agriculture biosecurity.

Novel nanoscale processes, materials, and systems with improved delivery efficacy, controlled release, modification of sensory attributes, and protection of micronutrients and functional ingredients suitable for food matrices.

Understanding nanoscale phenomena and processes to support the development of nano-based technologies for food and agricultural product quality monitoring, identity tracking, and preservation.

NEW: Assessment and analysis of perceptions and acceptance of nanotechnology and nano-based products by the general public, agriculture, and food stakeholders using appropriate social science tools.

12


Phytoglycogen dendrimer as nano-carrier for

antibacterial peptide loading and prolonged release

Advantages as controlled delivery of bioactive

compounds essential for the food safety and

nutrition and others

Surface treated nanoparticle-stabilized emulsion

much more effective than emulsions stabilized

using modified starch (WCS-OS) or Tween 20

Continuing research (NSF grants)(1) Biotechnology, Biochemical, and Biomass Engineering (BBBE), 01/01/2010 to 12/31/2012, Total fund: $327,603, PI: Yuan Yao, Co-PI: Arun Bhunia. Project title "Designing carbohydrate nanoparticles for prolonged efficacy of bacteriocin against food pathogens"

(2) Biomaterials, 07/15/2010 to 06/30/2013. Total fund: $350,000, PI: Yuan Yao, Co-PI: Ganesan Narsimhan, Project title "Dendrimer-like polysaccharides: structure, modification, and functional colloidal assembly".

0

1

2

3

4

5

6

7

0 10 20 30 40 50

Free nisin

PG-OS (DS 0.013)

WCS-OS (DS 0.013)

Tween 20

Size

of

inh

ibit

ory

rin

g, m

m

Storage time, Day

NSF Center Proposal

Industry-University Cooperative

Research Center (I-UCRC)

Brian Cunningham, PI, Illinois

Richard Linton, Co-PI, Purdue

Irfan Ahmad, Industry Liaison

December 7, 2009


Over 60 major NNI centers, networks, user facilities

Molecular Foundry(Lawrence Berkeley National Laboratory)

Center for Integrated Nanotechnologies

(Sandia & Los Alamos National Labs)

Cornell NanoScale Science & Technology

Facility (CNF)


NNI Areas of Investment(Program Component Areas)*

Fundamental Nanoscale Phenomena and Processes

Nanomaterials

Nanoscale Devices and Systems

Instrumentation Research, Metrology, and Standards for

Nanotechnology

Nanomanufacturing

Major Research Facilities and Instrumentation Acquisition

Environment, Health, and Safety (EHS)

Education and Societal Dimensions


NNI FY ‘11 Breakout by Program Component Area

Fundamental nanoscale phenomena and processes ($484 million)

Nanomaterials ($342 million)

Nanoscale devices and systems ($402 million)

Instrument Research, Metrology and Standards ($77 million)

Nanomanufacturing ($101 million)

Major research facilities and instrumentation acquisition ($203 million)

Environment, Health, and Safety ($117 million)

Education and Societal Dimensions ($35 million)


Environmental, Health, and Safety (EHS) Budget

* research whose primary purpose is to understand and address potential risks to health and to the environment from nanotechnology, e.g., not including related instrumentation research

$35$38

$48

$70

$87

$92

$117

9%

37%

100%

149%

163%

234%

13%19%

30%

42%48% 47%

0%

50%

100%

150%

200%

250%

$0

$20

$40

$60

$80

$100

$120

$140

2005 2006 2007 2008 2009 2010 2010

% growth EHS funding over 2005

% growth total NNI funding over 2005

NNI funding for nanotechnology-related EHS research* has grown much faster than the NNI as a whole.by fiscal year, in $ millions (FY 2010 is estimated, FY 2011 is requested)

2011


NNI EHS Strategy Development

Nanotechnology Environmental and Health Implications (NEHI) Working Group formed as informal body in 2003, formalized in 2005

Extraordinary collaboration between research and regulatory agencies

Began with review of respective agencies’ jurisdictions, responsibilities

Industry and non-governmental organizations provided input throughout

Environmental, health, and safety research needs published in September 2006: http://www.nano.gov/NNI_EHS_research_needs.pdf

Public meeting held in January 2007 to gather additional input from research community and public

Interim document for public comment, “Prioritization of Environmental, Health, and Safety Research Needs for Engineered Nanoscale Materials” published in August 2007: http://www.nano.gov/Prioritization_EHS_Research_Needs_Engineered_Nanoscale_Materials.pdf

First comprehensive NNI strategy document published in February 2008: http://www.nano.gov/NNI_EHS_research_needs.pdf

http://www.nano.gov/NNI_EHS_research_needs.pdf

http://www.nano.gov/Prioritization_EHS_Research_Needs_Engineered_Nanoscale_Materials.pdf

http://www.nano.gov/Prioritization_EHS_Research_Needs_Engineered_Nanoscale_Materials.pdf

http://www.nano.gov/NNI_EHS_research_needs.pdf


Role of nanotechnology-related EHS research in risk

management of nanomaterials*

* from Strategy for Nanotechnology-Related Environmental, Health, and Safety Research (February 2008): http://www.nano.gov/NNI_EHS_research_needs.pdf

NNI EHS Strategy


EPA-NSF-USDA/NIFA Joint Solicitation on EHS

Increasing Scientific Data on the Fate, Transport and Behavior of

Engineered Nanomaterials in Selected Environmental and

Biological Matrices

http://epa.gov/ncer/rfa/2010/2010_star_nano.html

Due: February 2, 2010

Research Area 1: Evaluation of potential exposures to

engineered nanomaterials including an exploration of

environmental and biological fate, transport, and

transformation of these materials throughout their lifetimes

Research Area 2: Improve the scientific understanding of

engineered nanoscale additives and ingredients that may be

intentionally introduced into food for delivery of important

micronutrients and modification of sensory attributes.

http://epa.gov/ncer/rfa/2010/2010_star_nano.html


How can industry tap into the NNI?

Direct funding via SBIR/STTR programs

Some agencies (e.g., DOD, NIH) can fund large company R&D directly also

Information on NNI-funded research projects

NSF and NIH provide online database of funded projects:

http://nsf.gov/awardsearch/

http://projectreporter.nih.gov/reporter.cfm

www.research.gov will provide comparable information Government-wide

NNI-funded user facilities available for use by industry

Government as first customer for innovative applications (e.g., National Reconnaissance Office, Navy)

Opportunities for industry to participate in NNI research planning workshops; contact NNCO if interested

http://nsf.gov/awardsearch/

http://projectreporter.nih.gov/reporter.cfm

http://www.research.gov/


SBIR and STTR funding for nanotechnology

2004 2005 2006 2007 2008

SBI

R STTR

Tota

l

SBI

R

STT

R

Tota

l

SBI

R

STT

R

Tota

l

SBI

RSTTR

Tota

l

SBI

RSTTR

Tota

l

DOE 6.8 2.8 9.6 7.7 0.4 8.1 18.2 1.6 19.8 17.4 0.8 18.2 13.8 2.7 16.5

NSF 11.9 0.9 12.8 12.1 5.5 17.6 13.9 1.8 15.7 13.4 3.8 17.2 10.5 7.5 18.0

DHHS/NIH 9.3 2.6 11.9 11.1 5.2 16.3 15.1 2.1 17.2 18.4 1.1 19.5 29.3 1.8 31.1

DOD 10.5 6.9 17.4 7.5 5.5 13 12.6 5.6 18.2 8.4 4.2 12.6 19.8 2.3 22.1

DOC/NIST 0.5 0.0 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.3 0.4 0.0 0.4

EPA 0.6 0.0 0.6 1.0 0.0 1.0 1.2 0.0 1.2 0.5 0.0 0.5 0.7 0.0 0.7

DHHS/NIOSH 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.4

NASA 7.2 0.6 7.8 6.0 0.0 6.0 12.1 1.5 13.6 11.7 1.5 13.2 6.2 0.8 7.0

USDA/FS 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3

USDA/NIFA 0.8 0.0 0.8 1.0 0.0 1.0 0.7 0.0 0.7 1.1 0.0 1.1 0.6 0.0 0.6

TOTAL 47.6 13.8 61.4 46.5 16.6 63.1 74.0 12.6 86.6 71.3 11.4 82.7 81.9 15.1 97.0

Over $390 million in nanotechnology-related Small

Business Innovation Research (SBIR) and Small

Business Technology Transfer (STTR) funding

between 2004 and 2008, inclusive


Industry Consultative Boards for Advancing Nanotech Key for development of nanotechnology, EHS coordination

CCR

Electronic Industry (Semiconductor Research Corporation lead),

October/2003 - Collaborative activities in key R&D areas 5

working groups, Periodical joint actions and reports; NSF-SRC

agreement for joint funding; other joint funding

Chemical Industry (Council for Chemical Research lead) - Joint

road map for nanomaterials R&D; Report in 2004; 2 working

groups, including one EHS Use of NNI R&D results, and one to

identify R&D opportunities

Organizations and business (Industrial Research Institute lead) -

Joint activities in R&D technology management; 2 working groups

(nanotech in industry, EHS) Exchange information, use NNI results,

support new topics

Forest products industries (AF&PA lead), April 2007 – Facilitate

forest products industry input to and communication with NSET


Education, other societal implications

Industry often cites main contribution of the Government is in education and training of the workforce

Over $260 million in NNI education and “ELSI” funding, 2005-2011, not including support for grad. students involved in substantive research

Obama Administration initiative, “Educate to Innovate”:

Cooperative effort between industry, government, and non-profit organizations

US$260 million in total

Includes $100 million from Time Warner Cable to produce shows that promote science and technology

Children's favorite Sesame Street will have a two-year focus on science

Discovery Communications will deliver science content to 60,000 schools, reaching 35 million pupils

Sony will support a challenge to design free, science-based video games

National Lab day, Ist week of May 2010

Also involves annual White House Science Fair


Nanotechnology in classroom

Hello, I am Miss Marble, Compared with earth we live on, I am in the Nano size. What is Nano? Nano: 1nm=10^-9m.

ACS NanoTube Contest - What is "Nano" ?


Effective Public Communication


Food Nanotechnology: Understanding the

Parameters of Consumer Acceptance

Understanding of acceptable characteristics and uses of

nanomaterials in food

Establish the baseline parameters of acceptability of

nanotechnologies in food. (Qualitative interviews)

Understand who may be most open to nanotech foods

(National survey)

Understand factors that influence acceptance (Food

sensory experiment)

PD: William K. Hallman, Rutgers U.


Summary: Recent NNI developments

Cumulative NNI funding for nanoscale science and engineering

research, 2001-2011: over $14 billion

Over 60 NNI research centers, networks and user facilities funded

Current NNI Strategic Plan released Dec. ’07; due for update 2010

NNI EHS strategy released Feb. ’08; also due for update soon

Over $480 million in “primary purpose” EHS R&D, 2005-2011

combined; over $260 million in education and ELSI funding over the

same period

Nanoscale science, engineering and technology for food applications

is still in its infancy – amply opportunities calls for private-public

partnership (PPP)

Transparent and proactive public engagement is a key for a

successful development and deployment of nanotechnology for the

societal and consumer benefits.

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