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MSH/SPS Swaziland Swaziland Essential Medicine List

Draft Version August 2009

WHO Essential Drug List Adaptation

1

THE ESSENTIAL MEDICINE LIST

OF

SWAZILAND

2nd

DRAFT

JANUARY 2011




2

Table of content

Table of content ____________________________________________________________________________________ 2

Introduction ________________________________________________________________________________________ 6

Motion To Amend The List Of Pharmaceuticals In The Public Sector ___________________________________________ 7

1 ANAESTHETICS _________________________________________________________________________________ 8

1.1 General Anaesthetics ________________________________________________________________________ 8

1.2 Local Anaesthetics __________________________________________________________________________ 8

1.3 Preoperative Medication and Sedation For Short Term Procedures __________________________________ 8

2 ANALGESICS, ANTIPYRETIC, NON-STEROIDAL ANTI-INFALMMATORY MEDICINES, MEDICINES USED TO TREAT GOUT AND DISEASE MODIFYING AFENTS IN RHEUMATOID DISORDERS ______________________________________ 9

2.1 Non-Opioids and Non-Steroidal Anti-Inflammatory Medicines ______________________________________ 9

2.2 Opioid Analgesics___________________________________________________________________________ 9

2.3 Medicines Used To Treat Gout _______________________________________________________________ 10

2.4 Disease Modifying Agents Used In Rheumatoid Disorders ________________________________________ 10

3 ANTI-ALLERGICS AND MEDICINES USED IN ANAPHYLAXIS ___________________________________________ 10

4 ANTIDOTES AND OTHER SUBSTANCES USED IN POISONINGS ________________________________________ 11

4.1 Non-Specific ______________________________________________________________________________ 11

4.2 Specific __________________________________________________________________________________ 11

5 ANTICONVULSANTS / ANTIEPILEPTICS ____________________________________________________________ 11

6 ANTI-INFECTIVE MEDICINES ______________________________________________________________________ 12

6.1 Anthelminthics ____________________________________________________________________________ 12

6.1.1 Intestinal Anthelminthics _________________________________________________________________ 12

6.1.2 Antischistosomals and Antitrematode Medicines _____________________________________________ 12

6.2 Antibiotics ________________________________________________________________________________ 12

6.2.1 Antibacterials ___________________________________________________________________________ 12

6.2.2 Antileprosy Medicines ___________________________________________________________________ 14

6.2.3 Antituberculosis Medicines _______________________________________________________________ 14

6.2.4 Reserve second-line medicines for the treatment of multidrug-resistant tuberculosis (MDR-TB) ______ 15

6.3 Antifungal Medicines _______________________________________________________________________ 15

6.4 Antimalarial Medicines ______________________________________________________________________ 16

6.4.1 For Curative Treatment ___________________________________________________________________ 16

6.4.2 For Prophylaxis _________________________________________________________________________ 16

6.5 Anti-pnemocystosis and Antitoxoplasmosis Medicines___________________________________________ 16

6.6 Antiprotozoal Medicines ____________________________________________________________________ 16

6.7 Antiretroviral Medicines _____________________________________________________________________ 16

6.7.1 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors _______________________________________ 16

6.7.2 Non-Nucleoside Reverse Transcriptase Inhibitors ____________________________________________ 17

6.7.3 Protease Inhibitors ______________________________________________________________________ 18

6.7.4 Fixed dosed Combinations ________________________________________________________________ 18

6.8 Antiviral Medicines _________________________________________________________________________ 19




3

7 ANTIMIGRAINE MEDICINES _______________________________________________________________________ 20

7.1 For Treatment Of Acute Attack _______________________________________________________________ 20

7.2 For Prophylaxis ____________________________________________________________________________ 20

8 ANTINEOPLASTIC, IMMUNOSUPPRESSIVES AND MEDICINES USED IN PALLIATIVE CARE _________________ 20

8.1 Immunosuppressive Medicines_______________________________________________________________ 20

8.2 Cytotoxic Medicines ________________________________________________________________________ 20

8.3 Hormones and Antihormones ________________________________________________________________ 21

9 ANTIPARKINSONISM MEDICINES __________________________________________________________________ 21

10 MEDICINES AFFECTING THE BLOOD ____________________________________________________________ 21

10.1 Antianaemia Medicines _____________________________________________________________________ 21

10.2 Medicines Affecting Coagulation _____________________________________________________________ 22

11 BLOOD PRODUCTS AND PLASMA SUBSTITUTES _________________________________________________ 22

11.1 Plasma Substitutes _________________________________________________________________________ 22

12 CARDIOVASCULAR MEDICINES ________________________________________________________________ 22

12.1 Antianginal Medicines ______________________________________________________________________ 22

12.2 Antiarrhythmic Medicines ___________________________________________________________________ 22

12.3 Antihypertensive Medicines _________________________________________________________________ 23

12.4 Medicines Used In Heart Failure ______________________________________________________________ 23

12.5 Antithrombotic Medicines ___________________________________________________________________ 24

13 DERMATOLOGICAL MEDICINES (Topical) ________________________________________________________ 24

13.1 Antifungal Medicines _______________________________________________________________________ 24

13.2 Anti-Infective Medicines _____________________________________________________________________ 24

13.3 Anti-Inflammatory and Antipruritic Medicines ___________________________________________________ 24

13.4 Scabicides and Pediculicides ________________________________________________________________ 24

13.5 Emollients ________________________________________________________________________________ 25

13.6 Keratoplastic and Keratolytic Medicines _______________________________________________________ 25

14 DIAGNOSTIC AGENTS _________________________________________________________________________ 25

14.1 Ophthalmic Medicines ______________________________________________________________________ 25

14.2 Radiocontrast Media speak with RFM _____________________________________________ 25

15 DISINFECTANTS AND ANTISEPTICS _____________________________________________________________ 26

15.1 Antiseptics________________________________________________________________________________ 26

15.2 Disinfectants ______________________________________________________________________________ 26

16 DIURETICS __________________________________________________________________________________ 26

17 GASTROINTESTINAL MEDICINES _______________________________________________________________ 26

17.1 Antacids and Antiulcer Medicines ____________________________________________________________ 26

17.2 Antiemetic Medicines _______________________________________________________________________ 27

17.3 Antihaemorrhoidal Medicines ________________________________________________________________ 27

17.4 Antispasmodic Medicines ___________________________________________________________________ 27




4

17.5 Laxatives _________________________________________________________________________________ 27

17.6 Medicines Used In Diarrhoea ________________________________________________________________ 28

17.7 Anti-Diarrhoeal Medicines ___________________________________________________________________ 28

17.8 Stomatological Medicines ___________________________________________________________________ 28

18 HORMONES, OTHER ENDOCRINE MEDICINES AND CONTRACEPTIVES _______________________________ 28

18.1 Contraceptives refer to family planning unit _______________________________________________ 28

18.1.1 Oral Hormonal Contraceptives _____________________________________________________________ 28

18.1.2 Injectable Hormonal Contraceptives ________________________________________________________ 28

18.1.3 Barrier Methods _________________________________________________________________________ 28

18.2 Insulin and Other Antidiabetic Medicines ______________________________________________________ 28

18.3 Ovulation Inducers _________________________________________________________________________ 29

18.4 Progestogen ______________________________________________________________________________ 29

18.5 Estrogen _________________________________________________________________________________ 29

18.6 Prostaglandins ____________________________________________________________________________ 29

18.7 Anti-lactating Agent ________________________________________________________________________ 29

18.8 Thyroid Hormones and antithyroid Medicines___________________________________________________ 29

19 IMMUNOLOGICALS ___________________________________________________________________________ 29

19.1 Sera and Immunoglobulins __________________________________________________________________ 29

19.2 Vaccines EPI __________________________________________________________________________ 30

19.2.1 For Immunization ________________________________________________________________________ 30

19.2.2 For Specific Groups of Individuals _________________________________________________________ 30

20 MUSCLE RELAXANTS (PERIPHERALLY-ACTING) AND CHOLINESTERASE INHIBITORS _________________ 30

21 OPTHALMOLOGICAL PREPARATIONS ___________________________________________________________ 31

21.1 Anti-Infective Agents _______________________________________________________________________ 31

21.2 Anti-Viral _________________________________________________________________________________ 31

21.3 Anti-Inflammatory Agents ___________________________________________________________________ 31

21.4 Anti-Inflammatory & Anti-Infective Agents______________________________________________________ 31

21.5 Anti-Allergic Agents ________________________________________________________________________ 32

21.6 Miotics and Antiglaucoma Medicines __________________________________________________________ 32

21.7 Mydriatics ________________________________________________________________________________ 32

21.8 Tear Replacement __________________________________________________________________________ 32

22 OTOLOGICALS _______________________________________________________________________________ 33

22.1 Anti-Infectives _____________________________________________________________________________ 33

22.2 Ear Wax Removal Products __________________________________________________________________ 33

22.3 Diagnostic Materials ________________________________________________________________________ 33

23 OXYTOCICS AND ANTIOXYTOCICS ______________________________________________________________ 33

23.1 Oxytocics _________________________________________________________________________________ 33

24 PSYCHOTHERAPEUTIC MEDICINES _____________________________________________________________ 33

24.1 Medicines Used in Psychotic Disorders ________________________________________________________ 33




5

24.2 Medicines Used in Mood Disorders ___________________________________________________________ 34

25 MEDICINES ACTING ON THE RESPIRATORY TRACT _______________________________________________ 35

25.1 Anti-Asthmatic Medicines ___________________________________________________________________ 35

25.2 Cold and Flu Preparations ___________________________________________________________________ 35

25.3 Nasal Decongestants _______________________________________________________________________ 35

26 SOLUTIONS CORRECTING WATER, ELECTROLYTE AND ACID-BASE DISTURBANCES __________________ 36

26.1 Oral ______________________________________________________________________________________ 36

26.2 Parenteral ________________________________________________________________________________ 36

26.3 Miscellaneous _____________________________________________________________________________ 36

27 VITAMINS AND MINERALS _____________________________________________________________________ 37

28 LIPID LOWERING DRUGS ______________________________________________________________________ 37

29 MUCOLYTIC AGENTS _________________________________________________________________________ 37

30 Miscellaneous ________________________________________________________________________________ 37




6

SWAZILAND ESSENTIAL MEDICINE LIST

Introduction

The Swaziland Essential Medicines List is a selection of medicines necessary to

meet the medical needs of the majority of people living in Swaziland. The

selection took into consideration many factors including disease patterns,

safety, efficacy and the total cost of therapy. The National Pharmaceutical

Policy calls for these medicines to be of acceptable standard of quality and be

made available through healthcare systems in adequate amounts and in the

described dosage forms. This list may be used as a guideline when developing

the Standard Treatment Guideline.

The Policy requires that medicines should be used in the appropriate manner

through the promotion of the concept of rational medicines use; to achieve this,

the medicines have been classified into four classes as indicated below, these

classes control the levels at which the different medicines can be prescribed

Class Description

A Indicates medicines that are distributed to all health care

facilities as part of primary healthcare services. Both doctors and

nurses can prescribe medicines from this class

B Indicates medicines that are distributed to Health-centres and

Hospitals. The prescribing of these medicines is restricted to

medical doctors only

C Indicates medicines that are distributed to hospitals only.

Medicines in this class can only be prescribed by medical doctors

working in hospitals, following appropriate microbial/diagnostic

test results

S These are medicines that are distributed on demand by specialist

doctors

* Indicates medicines which are distributed by (Vertical) National

Programmes e.g. Tuberculosis, Mental Health, Family Planning,

E.P.I., and Malaria Control

Comments to improve this list will be highly appreciated. These should be

accompanied by evidence-based motivation as indicated in page 2 of this

document. In addition, any information relating to product quality problems or

adverse reactions should be reported using the form attached at the end of this

document.




7

Motion To Amend The List Of Pharmaceuticals In The Public Sector

Please indicate nature of submission by marking the appropriate box

Deletion of listed medicine. Please attach proven evidence on

the harmful/useless effects of the medicine

Addition of a new medicine. Please attach evidence on proven

benefits of this medicine

Replacement of a listed medicine. Please attach evidence on

the proven benefit of such replacement over existing medicine

Name of medicine (generic):

Dosage form and strength:

Therapeutic class:

Reason for amendment:

Reference/s:

Advantage over existing medicine in the same therapeutic class:

Submitted by:

Address:

Contact person:

Telephone number:

Signature:

Date:

Please send to:

The Chief Pharmacist

Ministry of Health and Social Welfare

P.O. Box 5

Mbabane

Enquiries: Tel: 404 5525

Fax: 404 2092




8

1 ANAESTHETICS

1.1 General Anaesthetics

• Enflurane Inhalation B

• Isoflurane Inhalation B

• Halothane Inhalation B

• Ketamine Injection 50mg/ml B

• Propofol injection 1% 10mg/ml

B

• Thiopental Sodium Injection 01mg/10ml

B

• Nitrous Oxide and Oxygen Gas

B

• Etomidate injection 2mg/ml Consultation required

1.2 Local Anaesthetics

• Bupivacaine Hydrochloride Injection 5mg/ml

B

• Ethyl chloride spray A

• Ephedrine injection B

• Lignocaine Oral Spray C

• Lignocaine Plain Injection 2%

A

• Lignocaine-Epinephrine Dental Cartridges

B

• Oxybuprocaine Eye Drops 0.4%

B

1.3 Preoperative Medication and Sedation For Short Term

Procedures

• Atropine Injection 0.5mg/ml A

• Diazepam Injection 5mg/ml • Diazepam Tablets 5mg

A

B

• Fentanyl injection 100mg B

• Flumazenil injection 0.1mg/ml

B Consultation required




9

• Morphine Injection 15mg/ml • Morphine SR Tablets 30mg • Morphine powder 5mg/5ml

B

B

B

• Promethazine Injection 25mg

• Promethazine Tablets 25mg • Promethazine Syrup 5mg/5ml

B

B

B

2 ANALGESICS, ANTIPYRETIC, NON-STEROIDAL ANTI-INFALMMATORY

MEDICINES, MEDICINES USED TO TREAT GOUT AND DISEASE

MODIFYING AFENTS IN RHEUMATOID DISORDERS

2.1 Non-Opioids and Non-Steroidal Anti-Inflammatory Medicines

• Acetylsalicylic Acid Tablets 300mg

A

• Diclofenac Injection 75mg • Diclofenac suppositories 25mg

• Diclofenac Gel • Diclofenac Tablets 50mg

B

B To carry out a cost effective

analysis

S

B

• Ibuprofen 200mg tablets • Ibuprofen 400mg tablets • Ibuprofen syrup 100mg/5ml

A

A

A

• Paracetamol Tablets 500mg • Paracetamol Syrup 125mg/5ml

A

A

• Methylsalicylate ointment A

2.2 Opioid Analgesics

• Tramadol 50mg tablet • Tramadol 100 SR tablet

B

B

• Fentanyl injection 100mg B

• Morphine Injection 15mg/ml • Morphine SR Tablets 10mg • Morphine powder 5mg/5ml

B

B

B

• Pethidine Injection B




10

50mg/ml, 100mg/2ml

2.3 Medicines Used To Treat Gout

• Allopurinol Tablets 300mg B

• Diclofenac Tablets 50mg B

• Colchicine 0.5mg Tablet B

2.4 Disease Modifying Agents Used In Rheumatoid Disorders

• Chloroquine 200mg Tablets S

• Sulphasalasine Tablets 250mg

S

• Methotrexate 2.5mg S

3 ANTI-ALLERGICS AND MEDICINES USED IN ANAPHYLAXIS

• Cetirizine 10mg Tablets • Cetirizine 2.5mg/5ml Syrup

B

B

• Chlorpheniramine Tablets 4mg

• Chlorpheniramine 2mg/5ml syrup

A

A

• Dexamethasone Injection 4mg/ml

B

• Epinephrine (Adrenaline) Injection 1mg/ml

A

• Hydrocortisone Injection 100mg

• Hydrocortisone ointment 1%

B

B

• Methylprednisolone Injection 40mg

B

• Prednisolone Tablets 5mg B



A

A

A

A




11

4 ANTIDOTES AND OTHER SUBSTANCES USED IN POISONINGS

4.1 Non-Specific

• Charcoal Activated Powder A

4.2 Specific

• Atropine Injection 0.5mg/ml A

• Carbocysteine B

• Dantrolene 20mg/70ml B

• Obidoxime Chloride 250mg/ml Injection

B

• Naloxone Injection 0.4mg/ml

• Naloxone Injection 0.02mg/ml

B

B

• Methylene Blue Injection 100mg/10ml

B

5 ANTICONVULSANTS / ANTIEPILEPTICS

• Carbamazepine Tablets 200mg

• Carbamezapine Tablets CR 200mg

B*

B*

• Diazepam Injection 5mg/ml A

• Lorazepam Tablets 1mg B*

• Magnesium Sulfate Injection 50%

*For use in eclampsia and

severe pre-eclampsia and not

for other convulsant disorders

B

• Phenobarbital Injection 200mg

• Phenobarbital Tablets 30mg

B

B

• Phenytoin Capsules/tablets 100mg

• Phenytoin Injection

B*

B*




12

250mg/5ml

• Sodium Valproate injection 400mg/vial

• Sodium Valproate syrup 50mg/5ml

• Sodium Valproate tablets CR 200mg


B*

B*

B*

B*

6 ANTI-INFECTIVE MEDICINES

6.1 Anthelminthics

6.1.1 Intestinal Anthelminthics

• Albendazole Tablets 200mg • Albendazole Suspension 20mg/ml

A

A

• Ivermectine 50mcg S

• Praziquantel Tablets 600mg B

6.1.2 Antischistosomals and Antitrematode Medicines

• Praziquantel Tablets 600mg B*

6.2 Antibiotics

6.2.1 Antibacterials

• Amoxycillin Injection 500mg • Amoxycillin Capsules 250mg • Amoxycillin Capsules 500mg • Amoxycillin Suspension 125mg/5ml

B

A

A

A

• Amoxycillin-Clavulanic Acid Suspension 125-31mg/5ml

B

• Cefaclor Tablets 375mg • Cefaclor Suspension 187mg/5ml

B

B

• Cefazoline Injection 1g B

• Ceftriaxone Injection 1g C

• Ciprofloxacin Tablet 500mg A




13

• Ciprofloxacin Tablet 250mg • Ciprofloxacin injection 2mg/ml

C

C

• Clarithromycin tablets 250mg

• Clarithromycin suspension 125mg/5ml

S

B

• Clindamycin injection 600mg/4ml

• Clindamycin Capsules 150mg

• Clindamycin Suspension 75mg/5ml

C

C

C

• Cloxacillin Injection 500mg • Flucloxacillin Capsules 250mg

• Flucloxacillin Suspension 125mg/5ml

B

B

B

• Cotrimoxazole Injection 400/80mg/5ml

• Cotrimoxazole Tablets 400-80mg


• Cotrimoxazole Suspension 200-40mg/5ml

• Cotrimoxazole Tablets 100/20mg

B

A

A

A

A

• Doxycycline Tablets 100mg A

• Dapsone 100mg B

• Erythromycine Tablets 250mg

• Erythromycine Suspension 125mg/5ml

A

A

• Gentamycin Injection 80mg B

• Metronidazole Injection 500mg

B

A




14

• Metronidazole Tablets 200mg

• Metronidazole Suspension 125mg/5ml

A

• Nitrofurantoin Tablets 100mg C

• Penicillin Benzathine Benzyl Injection2.4MU

A

• Penicillin Benzyl Injection 5MU

A

• Penicillin Phenoxymethyl Tablets 250mg

• Penicillin Phenoxymethyl Suspension 125mg/5ml

A

A

• Penicillin Procaine Injection 300 000MU

A

• Spectinomycin Injection 2g A

• Vancomycin injection 1G C

6.2.2 Antileprosy Medicines

• Dapsone Tablets 100mg S*

• Rifampicin Capsules 150mg • Rifampacin capsules 300mg

S*

• Clofazimine Capsules 100mg

S*

6.2.3 Antituberculosis Medicines

• Ethambutol Tablets 400mg B*

• Isoniazid Tablets 100mg • Isoniazid Tablets 300mg

B*

• Pyrazinamide Tablets 500mg B*

• Rifabutin 150mg Tablets B*

• Rifampicin-Isoniazid Tablets 150-75mg, 300–150mg

B*

• Rifampicin-Isoniazid-Pyrazinamide Tablets 60–30–

150mg (Pediatric)

B*

• Rifampicin-Isoniazid-Pyrazinamide-Ethambutol

Tablets 150-75-400-275mg

B*




15

• Rifmapicin 150mg B*

• Rifabutin 150mg tablet B*

• Streptomycin Injection 1g B*

• Rifampicin 150, INH 75mg, Ethambutol 275mg

B*

6.2.4 Reserve second-line medicines for the treatment of multidrug-

resistant tuberculosis (MDR-TB)

• Clofazamine 100mg S*

• Capreomycin injection 1G S*

• Cycloserine Capsules 250mg

S*

• Ethionamide Tablets 250mg S*

• Kanamycin Injection 1g (Amikacin Injection 1g/4ml)

S*

• Moxifloxacin 400mg S*

• Ofloxacin Tablets 200mg S*

• Terizidone Capsules 250mg S*

6.3 Antifungal Medicines

• Amphotericin B Injection 50mg

B

• Clotrimazole Cream • Clotrimazole Lozenges 100mg

• Clotrimazole Pessaries 200mg

A

A

A

• Fluconazole Injection 2mg/ml

• Fluconazole Tablets 200mg • Fluconazole Suspension 50mg/5ml

B

B

B

• Griseofulvin Tablet 125mg • Griseofulvin Tablets 500mg

A

A

• Nystatin Suspension 100 000U

A




16

6.4 Antimalarial Medicines

6.4.1 For Curative Treatment

• Artemether/ Lumefantrine 20mg/120mg Tablet

A*

• Quinine Injection 600mg • Quinine Tablets 300mg

A*

A*

• Doxycycline Tablet 100mg • (For use only in combination with quinine)

A*

6.4.2 For Prophylaxis

• Mefloquine 250mg Tablet A*

• Doxycycline Tablets 100mg A*

6.5 Anti-pnemocystosis and Antitoxoplasmosis Medicines

• Cotrimoxazole Injection 400/80mg/5ml


• Cotrimoxazole Suspension 200-40mg/5ml

B

A

A

6.6 Antiprotozoal Medicines

• Metronidazole Injection 500mg

• Metronidazole Tablets 200mg

• Metronidazole Suspension 125mg/5ml

B

A

A

6.7 Antiretroviral Medicines

6.7.1 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors

• Abacavir (ABC) Tablets 300mg

• Abacavir (ABC) Oral Solution 100mg/5ml

B*

• Didanosine (ddI) Tablets B*




17

25mg

• Didanosine (ddI) Tablets 250mg EC


• Didanosine(ddI) Tablet 200mg EC


• Lamivudine (3TC) Tablets 150mg

• Lamivudine Oral Solution 50mg/5ml

B*

• Stavudine (d4T) Capsules 15mg

• Stavudine (d4T) Capsules 20mg

• Stavudine (d4T) Capsules 30mg,

B*

• Tenofovir disoproxil fumarate (TDF) 300 mg

• Zidovudine (AZT or ZDV) Capsules 100 mg

• Zidovudine (AZT or ZDV) Tablets 300mg

• Zidovudine (AZT or ZDV) Oral Solution 50mg/5ml

B*

6.7.2 Non-Nucleoside Reverse Transcriptase Inhibitors

• Efavirenz (EFV or EFZ) Capsules 50mg

• Efavirenz (EFV or EFZ) Capsules 200mg

• Efavirenz (EFV or EFZ) Caplet 600mg

B*

• Nevirapine (NVP) Tablets 200mg

• Nevirapine Oral Suspension

B*




18

50mg/5ml

6.7.3 Protease Inhibitors

• Indinavir (IDV) Capsules 200- • Indinavir (IDV) Capsules 400mg

B*

• Atazanavir 150mg S

• Ritonavir Tablet ( heat stable) 100mg

• Ritonavir Oral Solution 400mg/5ml

B*

• Lopinavir-Ritonavir Tablets 200/50mg

• Lopinavir-Ritonavir Tablets 100/25mg

• Lopinavir-Ritonavir Oral Solution 80/20mg/ml

B*

• Saquinavir (SQV) Capsules 200mg

B*

6.7.4 Fixed dosed Combinations

• Stavudine (D4T) / Lamivudine (3TC)

12mg/60mg tablet

B*


6mg/30mg tablet

B*

• Stavudine (D4T) 30mg/ Lamivudine (3TC)

150mg/Nevirapine 200mg

tablet

B*


/Nevirapine (NVP)

6mg/30mg/50 tablet

B*

• Stavudine (D4T)/ Lamivudine (3TC)

/Nevirapine (NVP)

12mg/60mg/100 tablet

B*




19

• Stavudine (d4T) Capsules 30mg/ Laminvudine 150mg

B*

• Tenofovir 300mg / Lamivudine 300

B*

• Tenofovir 300mg / emtricitabine 200

B*

• Tenofovir 300mg / Lamivudine 300mg /

Efavirenz 600mg

B*

• Tenofovir 300mg / emtricitabine 200 / Efavirenz

600mg

B*

• Zidovudine 60mg / Lamivudine 30mg Tablet

B*

• Zidovudine 300mg / Lamivudine 150mg Tablet

B*

• Zidovudine / Lamivudine / Efavirenz

300mg/150mg/600mg

B*

• Zidovudine 60mg / Lamivudine 30mg /

Nevirapine 50mg Tablet

B*

• Zidovudine 300mg / Lamivudine 150mg /

Nevirapine 200mg Tablet

B*

6.8 Antiviral Medicines

• Acyclovir Tablets 400mg • Acyclovir Ophthalmic Ointment 3%

• Acyclovir topical cream

A ( STI)

B

B

• Ganciclovir 500mg/vial (intraocular route)

S




20

7 ANTIMIGRAINE MEDICINES

7.1 For Treatment of Acute Attack

• Paracetamol Tablets 500mg A

7.2 For Prophylaxis

• Propranolol Tablets 10mg • Propranolol Tablets 40mg

B

• Amitryptyline 25mg B

8 ANTINEOPLASTIC, IMMUNOSUPPRESSIVES AND MEDICINES USED IN

PALLIATIVE CARE

8.1 Immunosuppressive Medicines

• Ciclosporin Injection 50mg/ml

• Ciclosporin Capsules 25mg

S

• Azathioprine 50mg Tablets S

8.2 Cytotoxic Medicines

• Adriamycin Injection 50mg/5ml

S

• Bleomycin Injection 15 units/vial

S

• Dacarbazine 200mg Injection

S

• Cyclophosphamide Injection 500mg

• Cyclophosphamide Tablets 25mg

S

• Fluorouracil Injection 50mg/ml

S

• Methotrexate Injection 25mg/ml

• Methotrexate Tablets 2.5mg

S

• Tamoxifen tablets 10mg S




21

• Vinblastin injection 10mg/ml S

• Vincristine Injection 2mg/mll S

8.3 Hormones and Antihormones

• Dexamethasone 4mg tabs B

• Dexamethasone Injection 4mg/ml

B

• Hydrocortisone Injection 100mg

B

9 ANTIPARKINSONISM MEDICINES

• Biperiden Injection 5mg • Biperiden Tablets 2mg

B*

• Carbidopa/ Levodopa 25/100mg

• Carbidopa/ Levodopa 50/200mg

• Bromocriptine 2.5mg

S

S

S

S

• Orphenadrine Tablets 50mg B*

• Trihexyphenidyl Tablets 2mg • Trihexyphenidyl Tablets 5mg

B*

10 MEDICINES AFFECTING THE BLOOD

10.1 Antianaemia Medicines

• Cyanocobalamin injection 1000mc/ml

S

• Ferrous Sulphate Tablets 200mg

A

• Erythropoietin injection 4000U

S

• Folic Acid Tablets 5mg A

• Ferrous-Folic Acid Syrup A

• Ferrous Sulphate syrup A

• Ferric hydroxide sucrose complex 100mg/ml

B




22

10.2 Medicines Affecting Coagulation

• Enoxaparin Sodium SC Injection 40mg/ml

S

• Heparin 5000iu/ml C

• Phytomenadione Injection 2mg/0.5ml

• Phytomenadione Injection 10mg/ml

A

• Tranexamic Acid Injection 250mg/ml

• Tranexamic Acid Tablets 500mg

B

B

• Warfarin Tablets 5mg B

11 BLOOD PRODUCTS AND PLASMA SUBSTITUTES

11.1 Plasma Substitutes

• Albumin 4% (Synthamin) S

• Albumin 20% S

• Dextran 70 Injectable Solution

B

• Pentastarch (Haesteril) 6% • Pentastarch (Haesteri) 10%

B

B

12 CARDIOVASCULAR MEDICINES

12.1 Antianginal Medicines

• Atenolol Tablets 50mg B

• Glyceryl Trinitrate Tablets B

• Isorsobide Dinitrate tablets 5mg

B

12.2 Antiarrhythmic Medicines

• Amiodarone Tablets 200mg B

• Amlodipine Tablets 10mg B

•




23

• Digoxin Injection0.5mg/2ml • Digoxin Tablets 0.0625mg, 0.25mg

B

B

• Diltiazam 60mg Tablets Consider Verapamil 40mg

depending on cost!

• Epinephrine (Adrenaline) Injection

B

• Lidocaine injection B

• Metoprolol tablets 100mg B

• Propranalol Tablets 10mg • Propranolol Tablets 40mg

B

• Quinine Tablets 300mg B

12.3 Antihypertensive Medicines

• Nifedipine Tablets 10mg • Nifedipine Tablets 20mg SR

B

• Atenolol Tablets 50mg B

• Captopril Tablets 12.5mg S For pead only

• Enalapril Tablets 5mg • Enalapril Tablets 20mg

B

B

• Furosemide Injection 20mg • Furosemide Tablets 40mg

B

• Di-Hydralazine Injection 20m B

• Hydrochlorothiazide Tablets 25mg

B

• Irbesartan Tablets 150mg B

• Methyldopa Tablets 250mg S ( only for pregnant women with

HT)

12.4 Medicines Used In Heart Failure

• Carvedilol 12.5mg B

• Digoxin Injection 0.5mg/2ml • Digoxin Tablets 0.0625mg, 0.25mg

S

• Enalapril Tablets 5mg • Enalapril 20mg

B

• Furosemide Injection 20mg B




24

• Furosemide Tablets 40mg


B

• Spironolactone Tablets 25mg, 100mg

B

12.5 Antithrombotic Medicines

• Acetylsalicylic Acid Tablets 150mg

A

• Dipyridamole 200mg SR Tablets

B

13 DERMATOLOGICAL MEDICINES (Topical)

13.1 Antifungal Medicines

• Benzoic Acid 6%-Salicylic Acid 3% Ointment

A

• Clotrimazole Cream 1% A

13.2 Anti-Infective Medicines

• Antiseptic cream A

• Ethanol 95-98% A

• Gentian Violet Solution A

• Ichthammol Glycerin A

• Povidone Cream • Povidone Solution • Povidone Scrub

A

A

B

• Silver Sulfadiazine Cream B

13.3 Anti-Inflammatory and Antipruritic Medicines

• Beclomethasone Cream 0.1%

B

• Calamine Lotion A

• Hydrocortisone Ointment 1% B

13.4 Scabicides and Pediculicides

• Benzyl Benzoate Lotion A




25

• Lindane Lotion A

• Sulfur 5% ointment A

• Sulfiram soap (Telmosol) A

13.5 Emollients

• Emulsifying Ointment A

• Zinc Oxide Cream A

13.6 Keratoplastic and Keratolytic Medicines

• Podophyllin Paint 25% A

• Silver Nitrate Stick A

14 DIAGNOSTIC AGENTS

14.1 Ophthalmic Medicines

• Fluorescein Paper Strips S

• Tropicamide Eye Drops 0.5% B

• Hydroxypropyl methylcellulose 2%

B

• Polyacrylic acid eye drops B

• Rose Benjal Drops or Paper Strips

S

• Hyarulonidase (Hyalose) Injection

S

• Healon Injectable S

• HP Methylcellulose 2ml vials S

• Sponge surgical spear opthalmic

S

14.2 Radiocontrast Media speak with RFM

• Barium Sulfate Contrast Meal

• Barium Sulfate Enema • Barium Sulfate Powder

B

B

B

• Gastrograffin B to remove

• Ultravist 300 • Ultravist 370

B

B




26

• Urografin Injection 30% • Urografin Injection 76%

B to remove

B to remove!

15 DISINFECTANTS AND ANTISEPTICS

15.1 Antiseptics

• Chlorhexidine Gluconate Solution

A

• Ethanol 95-98% A

• Hydrogen Peroxide 20% Solution

A

• Povidone Cream • Povidone Solution • Povidone Scrub

A

A

B

15.2 Disinfectants

• Gluteraldehyde Solution Pine(G-cide)

A

• Gluteraldehyde solution (cidex)

B

• Cetrimide-Chlorhexidine Solution

A

16 DIURETICS

• Furosemide Injection 20mg • Furosemide Tablets 40mg

B


B

• Mannitol Injectable Solution 20%

B

• Spironolactone Tablets 25mg, 100mg

B

17 GASTROINTESTINAL MEDICINES

17.1 Antacids and Antiulcer Medicines

• Aluminium-Magnesium Oral A




27

Suspension (Mayogel)

• Ranitidine Injection 50mg • Ranitidine Tablets 150mg

B

B

• Magnesium Hydroxide Tablet chewable

A

• Omeprazole Capsules 20mg B

17.2 Antiemetic Medicines

• Cyclizine 50mg B

• Metoclopramide Injection 10mg

• Metoclopramide Tablets10mg

B

B

• Ondansetron 4mg S check cost with same class

items



A

• Prochlorperazine Injection 25mg

• Prochlorperazine Tablets 5mg

B

B

17.3 Antihaemorrhoidal Medicines

• Haemorrhoidal Suppository B

• Anugesic Suppository B

17.4 Antispasmodic Medicines

• Hyoscine Butylbromide Injection 20mg/ml

• Hyoscine Butylbromide Tablets 10mg

A

17.5 Laxatives

• Bisacodyl Tablets 5mg B




28

• Glycerine Suppository peads

• Glycerine Suppository adults

B

B

• Magnesium Hydroxide Suspension

B

• Senokot Tablets B

17.6 Medicines Used In Diarrhoea

• Oral Rehydration Salts (low osmolarity)

A

• Zinc Sulphate Tablet 20mg A

17.7 Anti-Diarrhoeal Medicines

• Loperamide Tablets 2mg A

17.8 Stomatological Medicines

• Glycothymol Mouth Wash A

• Chlorhexidine Gluconate Mouth Wash 0.2%

B

18 HORMONES, OTHER ENDOCRINE MEDICINES AND CONTRACEPTIVES

18.1 Contraceptives refer to family planning unit

18.1.1 Oral Hormonal Contraceptives

• Lo-Feminal Tablet A*

• Ethinylestradiol –Norgestrel 50-500mcg (Ovral) Tablets

A*

18.1.2 Injectable Hormonal Contraceptives

• Norethisterone Enanthate (Nur-Isterate) Injection

200mg/ml

A*

18.1.3 Barrier Methods

• Condoms (Male and Female)

18.2 Insulin and Other Antidiabetic Medicines

• Insulin Mixed (Actraphane) B




29

Injection

• Insulin Soluble Injection (Actrapid)

B

• Insulin Neutral (Protaphane) Injection

B

• Gliclazide Tablets 80mg B

• Glibenclamide Tablets 5mg B

• Metformin Tablets 500mg • Metformin Tablets 850mg SR

B

B

18.3 Ovulation Inducers

• Clomiphene Tablets 50mg S

18.4 Progestogen

• Norethisterone Tablets 5mg B

18.5 Estrogen

• Conjugated Estrogen Tablets 0.625mg

B

18.6 Prostaglandins

• Dinoprostone Gel 0.5mg B

18.7 Anti-lactating Agent

• Bromocriptine Tablets 2.5mg B

18.8 Thyroid Hormones and antithyroid Medicines

• Carbimazole Tablets 5mg C

• Thyroxine Tablets 0.05mcg C

19 IMMUNOLOGICALS

19.1 Sera and Immunoglobulins

• Anti-D Immunoglobulin (human) Injection 500IU

C

• Rabies Immunoglobulin (Human) Injection 300IU/2ml

C




30

• Antivenon Polyvalent Injection

B

19.2 Vaccines EPI

19.2.1 For Immunization

• BCG Vaccine A*

• Diphtheria-Pertussis-Tetanus (DPT) Vaccine

• Diphtheria-Pertussis-Tetanus-Hepatitis B (DPTH) Vaccine

A*

• Diphtheria-Tetanus (DT) Vaccine

A*

• Hepatitis B Vaccine ( Peadiatrics 10 doses)

• Hepatitis B Vaccine (Adults 1 dose

A* to speak with EPI if to remove

• Measles Vaccine A*

• Pentavalent combination vaccine (DTPw-HB/Hib) 1

dose with VVM

• Poliomyelitis Vaccine A*

• Tetanus Toxoid (TT) Vaccine A*

19.2.2 For Specific Groups of Individuals

• Rabbies (Human) Vaccine A

• Yellow Fever Vaccine A*

20 MUSCLE RELAXANTS (PERIPHERALLY-ACTING) AND

CHOLINESTERASE INHIBITORS

• Pancuronium Bromide Injection 4mg/2ml

B

• Alcuroniun Chloride Injection 10mg/2ml

B

• Neostigmine Injection 2.5mg/l

B

• Suxamethonium Injection 100mg

B




31

21 OPTHALMOLOGICAL PREPARATIONS

21.1 Anti-Infective Agents

• Cefuroxime Injection B

• Chloramphenicol Eye Drops • Chloramphenicol Eye Ointment

A

A

• Ciprofloxacin Eye Drops 3mg/ml

S

• Gentamycin Eye Drops B

• Natamycin Eye Drops • Natamycin Eye Ointment

B

B

• Sulphacetamide Eye Drops 10%

B

• Tetracycline Eye Ointment 1%

A

21.2 Anti-Viral

• Acyclovir Eye Ointment B

• Ganciclovir 500mg/vial Injection

B

21.3 Anti-Inflammatory Agents

• Dexamethasone Eye Drops 0.1%

B

• Diclofenac Sodium eye drops 1mg/ml

B

• Fluorometholone Eye Drops B

• Hydrocortisone Eye Drops B

• Prednisolone Forte Eye Drops

B

21.4 Anti-Inflammatory & Anti-Infective Agents

• Betamethasone drops 0.1% • Betamethasone 0.1%- Neomycin 0.35% drops

B

B




32

• Dexmethasone-Chloramphenicol Eye Drops

B

• Dexamethasone-chloramphenicol-neomycin

(Covoycin D) drops

• Chloramphenocol-neomycin (Covomycin)

drops

B

B


21.5 Anti-Allergic Agents

• Antazoline-Tetrazoline Eye Drops

A

• Sodium Cromoglycate Eye Drops

A

21.6 Miotics and Antiglaucoma Medicines

• Acetazolamide Tablets 250mg

B

• Dorzolamide Eye Drops B

• Latanoprost Eye Drops 0.005%

B

• Pilocarpine Eye Drops 2% B

• Pilocarpine Intracameral Injectable

B

• Timolol Eye Drops 0.25% • Timolol Eye Drops 0.5%

B

B

21.7 Mydriatics

• Atropine Eye Drops 1% B

• Homatropine Eye Drops 2% B

21.8 Tear Replacement

• Hydroxypropyl methylcellulose 2%

B


• Tears Naturelle B confirmed




33

22 OTOLOGICALS

22.1 Anti-Infectives

• Chloramphenicol Ear Drops B

22.2 Ear Wax Removal Products

• Dichlorobenzene Ear Drops B

22.3 Diagnostic Materials

• Impression material ear B

• Investment gel ear B

• Wax (for hardening ear impression)

B

23 OXYTOCICS AND ANTIOXYTOCICS

23.1 Oxytocics

• Ergometrine Injection 200mcg

• Ergometrine Tablets

B

B

• Oxytocin Injection 5IU B

• Oxytocin-Ergometrine Injection

B

• Misoprostol Tablets 200mcg S handle as habit forming

drug

24 PSYCHOTHERAPEUTIC MEDICINES

24.1 Medicines Used in Psychotic Disorders

• Chlorpromazine Injection 100mg

• Chlorpromazine Tablets 50mg

• Chlorpromazine Tablets 100mg

B*

B*

B*

• Fluphenazine Decanoate Injection 25mg/ml

B*




34

• Flupenthixol Injection 20mg/ml

B*

• Haloperidol Injection 5mg • Haloperidol Tablets 1.5mg • Haloperidol Tablets 5mg

B*

• Lithium Carbonate 400mg tablet

S*

• Olanzapine Tablets 5mg B* add 10mg strength consider

cost

• Sulpiride Capsules 100mg B*

• Risperidone Tablets 2mg B* add 4 mg consider cost

• Trifluoperazine Tablets 5mg B*

• Zuclopenthixol Decanoate Injection 200mg

B*

24.2 Medicines Used in Mood Disorders

24.2.1 Medicines Used in Depressive Disorders

• Amitriptyline Tablets 25mg B*

• Fluoxetine Tablets 20mg B*

• Gabapentin 300mg Capsules

S*

• Imipramine Tablets 25mg B*

• Sertraline 50mg Tablets B*

24.2.2 Medicines Used in Bipolar Disorders

• Carbamazepine Tablets 200mg

• Carbamezapine CR Tablets 200mg

B*

• Sodium Valproate injection 400mg/vial

• Sodium Valproate syrup 50mg/5ml



• Sodium Valproate tablets

B*




35

CR 500mg

24.2.3Medicines Used in Generalized Anxiety and Sleep Disorders

• Diazepam Injection 10mg • Diazepam Tablets 5mg

B

B

• Lorazepam Tablets 2mg • Lorazepam Injection 4mg/ml

B*

B*

• Methylphenidate 10mg Tablets

S*

25 MEDICINES ACTING ON THE RESPIRATORY TRACT

25.1 Anti-Asthmatic Medicines

• Aminophylline Injection 25mg/ml

B

• Beclomethasone Inhalation (aerosol) 50mcg

• Beclomethasone Inhalation (aerosol 100mcg

B

B

• Epinephrine (Adrenaline) Injection

A

• Salbutamol Inhalation (Aerosol) 50mcg,

• Salbutamol Inhalation (Aerosol) 200mcg

• Salbutamol & Ipratropium Bromide Nebulizing solution

A

A

A

• Salmeterol B

25.2 Cold and Flu Preparations

• Ascobic Acid Tablets 250mg A

• Cold and Flu Tablets A

25.3 Nasal Decongestants

• Oxymetazoline Nasal Drops 0.5%

B

• Fluticasone nasal spray B




36

26 SOLUTIONS CORRECTING WATER, ELECTROLYTE AND ACID-BASE

DISTURBANCES

26.1 Oral

• Oral Rehydration Salts (Low osmolarity)

A

26.2 Parenteral

• Darrows Half Strength Solution

B

• Dextrose Solution 5% • Dextrose Solution 10% • Dextrose Solution 50%

A

B

B

• Dextrose 5%-Sodium Chloride 9% Solution

A

• Mentelyte injection B

• Neolyte infussion B

• Pentastarch 6% B

• Plasmalyte B Injection B

• Polygeline injection (haemacel)

B To consult with PPK

• Potassium Chloride Injection 20%

• Potassium Chloride Tablets SR 600mg

B

• Potassium Citrate 30% B

• Ringers Lactate Solution A

• Sodium Bicarbonate Injection 8.5%

B

• Sodium Chloride Solution 0.9%

A

26.3 Miscellaneous

• Water For Injection 10ml A




37

27 VITAMINS AND MINERALS

• Ascorbic Acid Tablets 250mg

A

• Calcium Gluconate Injection 10%

• Calcium Gluconate Tablets 300mg

A

A

• Micronutrients A

• Multivitamin Tablets • Multivitamin Syrup

A

A

• Nicotinamide Tablets 100mg A

• Pyridoxine Tablets 25mg A

• Retinol Tablets A

• Thiamine Tablets 100mg A

• Vitamin B Complex Injection • Vitamin B Complex Tablets

A

A

28 LIPID LOWERING DRUGS

• Atorvastatin Tablets 10mg B

29 MUCOLYTIC AGENTS

• Carbocisteine syrup A

30 Miscellaneous

• Cod liver oil Capsules B

• Formalin 40%

• Glycerine BP

• Lubricating gel

• Methylated spirit

• Sodium Hypochlorite (JIK)

• Ultrasound gel

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