Date post: | 28-Dec-2015 |
Category: |
Documents |
Upload: | julianna-pitts |
View: | 216 times |
Download: | 0 times |
The Immune System
memory and specificity
Chapter 43http://www.cellsalive.com/antibody.htmhttp://inet.uni2.dk/~iirrh/IIRhome.htm
Topics in Immunity• Allergies:--plasma cells, immunoglobulins, and mast cells
--antibodies and antigens
• HIV-AIDS-- infection of T cells-- place of T cells in the immune system
• distinguishing self from non-self
© Dennis Kunkel
One of the culprits: ragweed pollen
Figure 42.14x Blood smear
Figures 42.15 & 16 Types and Differentiation of blood cells
Figure 43.8a,b The structure of a typical antibody molecule
Table 43.1 The Five Classes of Immunoglobulins
Figure 43.16 Effector mechanisms of humoral immunity
Figure 43.12 Clonal selection of B cells
Timing of primary and secondary immune response
pollen (the allergen) stimulates histamine release from mast cells
Figure 43.18 Mast cells, IgE, and the allergic response
Figure 43.14 An overview of the acquired immune responses 2
Topics in Immunity• Allergies:--plasma cells, immunoglobulins, and mast cells
--antibodies and antigens
• HIV-AIDS-- infection of T cells-- place of T cells in the immune system
• distinguishing self from non-self
Figure 42.14x Blood smear
Figures 42.15 & 16 Types and Differentiation of blood cells
Figure 43.9 The interaction of T cells with MHC molecules
Structure and positioning of the Major histo-compatibility complex (MHC) proteins
Class I Class II
Interaction of an MHC protein with its antigen
Class I
Cytotoxic T cell action (FIG. 43.16)
Clonal selection of Helper T cells and Cytotoxic T cells (FIG. 43.15)
Figure 43.14 An overview of the acquired immune responses 1
Figure 43.14 An overview of the acquired immune responses 2
Figure 43.14 An overview of the acquired immune responses 2
Figure 43.14 An overview of the acquired immune responses 3
Presenting antigens: CD4 helps stabilize the connection.
(usually a macrophage)
Figure 43.19 A T cell infected with HIV
Figure 43.19x1 HIV on a lymphocyte, detail
Figure 18.7 HIV, a retrovirus
Figure 43.19x2 HIV budding
Figure 43.20 The stages of HIV infection
Only cells with both CD4 proteins and chemokine receptor proteins (CXCR4, CCR5) are vulnerable to the HIV virus.
These are the central cells in the immune system.
Figure 43.14 An overview of the acquired immune responses 3
Figure 43.14 Epitopes (antigenic determinants)
Topics in Immunity• Allergies:--plasma cells, immunoglobulins, and mast cells
--antibodies and antigens
• HIV-AIDS-- infection of T cells-- place of T cells in the immune system
• distinguishing self from non-self