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The LICOX System® Brain Tissue Oxygen Monitoring
System
Jeffrey McCarthy
Biomedical Engineering
University of Rhode Island
The Licox Monitor
• Measures the amount of
Oxygen (O2) that is
reaching the brain tissue
– Partial Pressure of Brain
Tissue Oxygenation (PbtO2)
– Normal PbtO2: 25-35 mmHg
• Continuous, real time
measurement
Why?
• Cerebral Hypoxia is associated with poor
neurological outcome
– Medical interventions can attempt to correct PbtO2
• Causes of Cerebral Hypoxia
– Stroke
– Traumatic Brain Injury (TBI)
– Vasospasm related to Subarachnoid Hemorrhage
How Does It Work?
• Probe covered by an O2 permeable
membrane
• O2 diffuses from brain through membrane
• Inside probe is an electrolyte solution
• O2 changes the charge of the solution
• Charge is carried through cables to the external Licox computer and displayed
References:1. “The LICOX System” Integra NeuroSciences 4 April 2013 http
://www.integralife.com/products%2FPDFs%2FNeuroCriticalCare%2FLicox%20Sales%
20Brochure.pdf
2. Northern Illawarra Hospitals Group: Clinical Practice Guideline
http://intensivecare.hsnet.nsw.gov.au/five/doc/wollongong/
june_licox_clinical_practice_guideline_wollongong.pdf
3. “The LICOX Sytstem: Product Presentation” Integra
NeuroSciences 4 April 2013
http://www.integralife.com/index.aspx?redir=products#Oti