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The Medical Research Council
Presentation to the Portfolio Committee on Science and Technology
March 16, 2005
http://www.mrc.ac.za
VISION
Building a healthy nation through research
MISSION
To improve the nation’s health status and quality of life through relevant and excellent health research aimed at promoting equity and development
MRCBUILDING A HEALTHY NATION THROUGH
RESEARCH
MRCCape Town
MRCDurban
MRCPretoria
• A Statutory Council – one of 9 Science
Councils
• Established by Act of Parliament
• 9% of Science Vote
• Turnover ~R350 million (60% baseline)
• Staff 800
• 48 Intra- and Extra-mural Research Units
Board President
Executive Management Committee
Environment and Development
Alcohol and Drug Abuse Research Unit
Exercise Science and Sports Medicine Research Unit
Health and Development Research Group
Health Promotion Research and Development Group
Woman and Child Health
Gender and Health Research Unit
Maternal and Infant Health Care Strategies Research Unit
Mineral Metabolism Research Unit
Nutritional Intervention Research Unit
Infection and Immunity
HIV and AIDS Research Lead Programme
Clinical and Biomedical Tuberculosis Research Unit
Diarrhoeal Pathogens Research Unit
Genital Ulcer Disease Research Unit
HIV Prevention and Vaccine Research Unit
South African AIDS Vaccine Initiative
Immunology of Infectious Disease Research Unit
Inflammation and Immunity Research Unit
Malaria Research Lead Programme
Operational and Policy Tuberculosis Research Group
Pneumococcal and Meningeal Pathogens Research Unit
South African Traditional Medicines Research Unit
Tuberculosis Research Lead Programme
Non Communicable Disease
Anxiety and Stress Disorders Research Unit
Cancer Epidemiology Research Group
Chronic Diseases of Lifestyle Research Unit
Crime, Violence and Injury Lead Programme
Diabetes Research Lead Programme
Interuniversity Cape Heart Research Group
Medical Imaging Research Unit
PROMEC Unit
Health Systems and Policy
Burden of Disease Research Unit
Biostatistics Unit
Cochrane Centre
Health Policy Research Group
Health Systems Research Unit
National Telemedicine Lead Programme
Molecules to Disease
Bioinformatics Capacity Development Research Unit
Bone Research Unit
Centre for Molecular and Cellular Biology
Human Genetics Research Unit
Human Genomic Diversity and Disease Research Unit
Liver Research Centre
Molecular Hepatology Research Unit
Molecular Mycobacteriology Research Unit
Oesophageal Cancer Research Group
SA MRC/British MRC Receptor Biology Research Group
Indigenous Knowledge Systems Research Lead Programme
Income and income distribution in South Africa and selected countries
Source: Human Development Report 2000
Per capita income
1998 PPP$
Share of income or consumption 1987-1998
Country
Poorest 20% Richest 20% Richest 20% to
poorest 20%
South Africa 3,918 2.9 64.8 22.3
South and East African Countries
Botswana 3,611 .. .. ..
Burundi 147 7.9 41.6 5.3
Kenya 334 5.0 50.2 10.0
Lesotho 486 2.8 60.1 21.5
Mozambique 188 6.5 46.5 7.2
Namibia 2,133 .. .. ..
Rwanda 227 9.7 39.1 4.0
Swaziland 1,409 2.7 64.4 23.9
Tanzania, U. Rep. of 173 6.8 45.5 6.7
Uganda 332 6.6 46.1 7.0
Zambia 388 4.2 54.8 13.0
Zimbabwe 703 4.0 62.3 15.6
Selected developing countries
Brazil 4,509 2.5 63.8 25.5
Philippines 1,092 5.4 52.3 9.7
Sri Lanka 802 8.0 42.8 5.4
Thailand 2,593 6.4 48.4 7.6
Infant Mortality Rate by Population Group SADHS 1998
53.6
38.7
18.8
11.4
45.4
0
10
20
30
40
50
60
Non-urban African Urban African Coloured White Total
de
ath
s p
er
1000 b
irth
s
Province
House Type Piped water inside
%
Without toilet
%
Reporting hunger
% %
traditional % shack
Eastern Cape 31.9 12.1 23.4 25.1 30.9
Free State 7.0 19.4 29.9 5.3 23.8
Gauteng 0.2 24.7 58.8 0.8 14.7
Kwa-Zulu Natal
18.6 19.3 34.6 12.7 26.8
Mpumalanga 8.7 17.5 27.6 3.5 31.9
Northern Cape
0.9 12.9 48.1 10.7 15.1
Northern 15.2 6.2 12.1 18.8 15.5
Northern West
1.7 12.1 21.6 5.7 22.5
Western Cape
0.2 15.9 76.7 3.8 15.0
South Africa 10.9
16.9
38.8
9.7
21.9
Source: StatsSA 1999 October Household Survey
Variations in household living conditions by province, 1999
Figure 1 : Prevalence of HIV among antenatal care attendees in South Africa, 1990-2003
0.71.7 2.2
4
7.6
10.4
14.2
17
22.8 22.4
24.5 24.826.5
27.9
0
5
10
15
20
25
30
1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003
Year
HIV
Pre
vale
nce (
%)
HIV prevalence levels by sex and
age group in 2004
0%
5%
10%
15%
20%
25%
30%
35%
0-4
5-9
10-1
4
15-1
9
20-2
4
25-2
9
30-3
4
35-3
9
40-4
4
45-4
9
50-5
4
55-5
9
60-6
4
65-6
9
70-7
4
75-7
9
80-8
4
85+
Age group
Per
cen
tag
e
Males
Females
Figure 4 : HIV and syphilis prevalence among ANC attendees aged below 20 years in South Africa : 1991 - 2003
0
2
4
6
8
10
12
14
16
18
20
22
24
1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003
Year
Pre
va
len
ce
ra
te (
%)
HIV RPR
Note : RPR trends by age are shown from 1998 when these became available
Cause Deaths PercentageTuberculosis
Influenza and pneumonia
Other forms of heart disease
Stroke
Hypertensive heart disease
Chronic bronchitis
General Symptoms and Signs
Ischaemic heart disease
Resp and cardiac in perinatal period
Diabetes mellitus
HIV disease
TOTAL
56 985
55 115
48 927
31 104
27 622
20 136
19 454
17 380
17 191
16 207
9 479
339 928
16.1
15.5
13.7
8.7
7.8
5.9
5.7
5.1
5.1
4.8
2.8
100
Number of associated deaths for the ten leading reported natural causes of death in 2001
Source: Statistics South Africa 2005
Cause Deaths Percentage
HIV/AIDS
Ischaemic heart disease
Homicide/violence
Stroke
Tuberculosis
Lower respiratory infections
Road traffic accidents
Diarrhoeal diseases
Hypertensive heart disease
Diabetes mellitus
165 859
32 919
32 485
32 114
29 553
22 097
18 446
15 910
14 233
13 157
29.8%
5.9%
5.8%
5.8%
5.3%
4.0%
3.3%
2.9%
2.6%
2.4%
Top 10 causes of death, South Africa 2000 National Burden of Disease Study, Total deaths 556 585
Source: Bradshaw et al., 2003
Estimated population pyramid, 2004 MRCBurden of Disease Research Unit
3000000 2000000 1000000 0 1000000 2000000 3000000
0 - 4
5-9
10-14
15 -19
20 - 24
25 - 29
30 - 34
35 - 39
40 - 44
45 - 49
50 - 54
55 - 59
60 - 64
65 - 69
70 - 74
75 - 79
80 - 84
85 +
Male Female