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The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
PRISMA Checklist
17. Selecting the studies (flow diagram)
18. Characteristics of single studies → number, “PICOS”, follow-up, etc.
(narrative synthesis and/or table)
19. Analysis of “bias” risk in each study → randomized (Jadad score, Cochrane risk of bias
tool), observational (Newcastle-Ottawa scale) (table)
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
PRISMA Checklist
20. Results of single studies: a) essential data on all considered “outcomes” for each treatment group (table)
b)estimates of efficacy and confidence intervals (forest plot)
21. Summary of results:meta-analisis with efficacy estimates,
confidence intervals and measures of consistency (narrative sythesis and/or tables)
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
PRISMA Checklist
22. Analysis of bias risk among various studies: “publication bias”, heterogenity (funnel plot)
23. Secondary analises : of senstivity, for sub-groups, etc.
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
“Review Article: how to summarize the evidence”
The Platinum Journal
“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -
Venezia 2012
• Clear, objective and balanced presentation
• qualatative and quantatative descriptions
• Critical analysis of controversial points
• Critical analysis of the weakneses of the included studies
How to summarize the results?
“Review Article: how to summarize the evidence”