+ All Categories
Home > Documents > The research commercialisation office of the University of ......conducting due diligence on...

The research commercialisation office of the University of ......conducting due diligence on...

Date post: 11-Jul-2020
Category:
Upload: others
View: 0 times
Download: 0 times
Share this document with a friend
12
The research commercialisation office of the University of Oxford, previously called Isis Innovation, has been renamed Oxford University Innovation All documents and other materials will be updated accordingly. In the meantime the remaining content of this Isis Innovation document is still valid. URLs beginning www.isis-innovation.com/... are automatically redirected to our new domain, www.innovation.ox.ac.uk/... Phone numbers and email addresses for individual members of staff are unchanged Email : [email protected]
Transcript
Page 1: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

The research commercialisation office of the University

of Oxford, previously called Isis Innovation, has been

renamed Oxford University Innovation

All documents and other materials will be updated accordingly.

In the meantime the remaining content of this Isis Innovation

document is still valid.

URLs beginning www.isis-innovation.com/... are automatically

redirected to our new domain, www.innovation.ox.ac.uk/...

Phone numbers and email addresses for individual

members of staff are unchanged

Email : [email protected]

Page 2: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

UNIVERSITIES INDUSTRY

INVESTORS GOVERNMENT

2012A N N U A L R E P O R T

Page 3: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

1

Isis Innovation Ltd is a growing and successful business owned by the University of Oxford. Oxford

is the biggest research-based University in the UK, with research expenditure of £501m last year. Isis

manages the University’s IP by investing to protect the intellectual property arising from the University’s

research activities and then transferring the IP for further investment and development by third parties

around the world.

Chairman’s Introduction 1

Review of the Year 2

Working for Universities 4

Working for Industry 6

Working with Investors 8

Working with Government 10

Communications 12

International Platforms 13

Accounts 14

Company Details 16

Isis Innovation Ltd is wholly owned by the

University of Oxford and manages a number of IP

commercialisation activities as described in this

report. Isis is a profitable business and during the

year generated a substantial net return of funds to

the University. In addition, Isis provides a number of

other assets and benefits for the University.

Isis works for universities and industry to transfer

technologies and expertise. Isis works with investors

to support early stage companies and with government

to develop sustainable economic growth.

Tom Hockaday, Managing Director

Contents Chairman’s Introduction

Providing access to academic consultancy and services from

the University of Oxford.

Delivering consultancy to companies, governments, and technology

transfer organisations worldwide.

Managing the commercialisation of IP developed in Oxford – licensing,

spin-outs and material sales.

Oxford University Consulting has had a very successful

year connecting the expertise of Oxford’s academic

community to client organisations around the world.

OUC has been part of Isis for ten years and is now

very well established in managing academic consulting

relationships. Over the ten years OUC has facilitated

many hundreds of consulting relationships between

academics and clients, often leading to long term

collaborations.

Isis Enterprise continues to promote and sell

our expertise around the world, helping

technology providers and seekers to

source, commercialise and develop

new technologies. In addition, Isis

Enterprise assists governments and

other organisations interested

in establishing their own

innovation activities.

I would like to thank all

the Isis staff, and those

in the University who

work closely with them,

for their considerable

hard work and continued

commitment during this

very successful year.

Isis revenues increased by 21% to £10.2m with growth

across all areas of the business. Over the last ten

years Isis revenues have shown a compound annual

growth rate of 20%. This is an impressive business

performance, especially in recent years with continuing

economic challenges in many regions. Isis now has

offices in Oxford, Madrid, Hong Kong and Kyoto to

enable it to transfer technologies and investment

opportunities, and develop technology management

capabilities around the world.

Isis continues to deliver a positive return on investment

to the University each year. The University provides Isis

with £2.5m to invest in protecting intellectual property

arising from the University’s research activities. This

involves managing a strong portfolio of international

patents, technology licensing deals and new company

formation. This year Isis generated a return to the

University and its researchers of £5.3m, and created

shareholdings for the University in five new spin-out

companies worth £3m.

Technology commercialisation is of growing importance

to the University, to organisations that fund research

in universities, to governments and the economy.

Translating the outputs of early stage university research

from the academic world to the business environment

allows novel ideas to become new products which

address current global challenges in areas such as

healthcare, the environment and communications.

Isis generated a return to the University and its researchers of

£5.3m, and created shareholdings for the University in five new

spin-out companies worth £3m.

Bernard Taylor, Chairman

Page 4: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

3

Total Isis revenues in 2012 (2011: £8.4m)

£10.2

Revenues

Isis offices in Oxford, Hong Kong, Kyoto and Madrid

4InTeRnATIOnAL PLATFORMs

New companies supported by the Isis Software Incubator

3sOFTWARe sTART-uPs

University shares in Oxford spin-outs established by Isis valued at July 2012 (2011: £35m)

Technology Licence and Oxford University Consulting deals signed (2011: 292)

£45

356

sPIn-OuT sHARe PORTFOLIO

DeALs

Returned to Oxford University and its researchers (2011: £4.8m)

£5.3 mil

lio

n

mil

lio

nm

illio

n

DIsTRIbuTIOns

Isis delivered another very strong performance in 2012 both in terms of transferring new ideas out to industry and

generating financial returns for the University.

Return on Investment to the University of Oxford

Over the year, Isis returned £5.3m to the University and its researchers (an increase of 10% overall from 2011). Isis

provided the University with shareholdings in five new spin-out companies (valued at £3m), invested £2.85m in

protecting University intellectual property, increased the University’s assets by 100 new patent applications, and

assisted Oxford researchers in winning translational funding awards totalling £4.4m. This was the fourth year of the

current five year growth plan for Isis, with Isis receiving from the University an annual subvention of £2.5m.

Revenue growth

Isis revenues increased by 21% to £10.2m (2011: £8.4m). This is an impressive business performance during a year of

continued challenging circumstances from the global financial crisis and recession in a number of countries.

The Technology Transfer Group revenues increased by 17% to £6.4m (2011: £5.4m).•

Oxford University Consulting revenues by 56% to £1.9m (2011: £1.2m).•

Isis Enterprise revenues increased by 16% to £1.6m (2011: £1.4m).•

Isis is responsible for these activities:

Technology Transfer for Oxford

Isis helps Oxford University researchers to commercialise intellectual property arising from their research: patenting;

copyright; licensing; spin-out companies; research reagents and patient reported outcome measures. Isis manages

the following:

Isis Angels Network

IAN introduces private investors and seed/venture capitalists interested in investing in Oxford spin-out

companies to investment opportunities, on behalf of the University.

Oxford University Challenge Seed Fund

Isis manages this Fund on behalf of the University to provide financial investment for accelerating the

transfer of Oxford technologies to market.

Oxford Invention Fund

Isis has launched the Oxford Invention Fund (OIF) with the University’s Development Office as part of

Oxford Thinking, a united Campaign for the collegiate University.

Isis Software Incubator

The incubator supports Oxford University staff and students to develop software business ventures by

offering specific technical and commercial advice, and allowing incubatees to develop their products

and start trading.

Oxford University Consulting

Isis manages OUC which helps Oxford University researchers to identify and manage consulting opportunities and

helps clients access expertise from Oxford’s world-class, interdisciplinary research base.

Oxford Innovation Society

Isis runs the Oxford Innovation Society, a leading forum for open innovation, bringing together industry, investors,

government and the business professions with researchers and inventors from the University.

Isis Enterprise

Isis provides consulting expertise and advice in technology transfer and innovation management to clients across the

public and private sectors around the world.

Isis is a world leading technology transfer business, creating links between the outstanding research capability at

Oxford, and elsewhere, for the benefit of society in the UK and around the world. Isis provides opportunities for

business to create sustainable economic growth. There are many ways to present the activities of Isis; these are some

of the numerical outputs.

Review of the year Isis Highlights

2

Invested in the five new spin-out companies created in the year (2011: £1.4m in 4 new spin-outs)

£4.9

neW sPIn-OuTs

mil

lio

n

Isis compound annual growth rate over last ten years

20%

GROWTH

Page 5: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

5

Working for Universities

Isis manages technology transfer for the University of Oxford, and provides technology transfer services

and advice to universities around the world. Our approach is to assist researchers to commercialise

the results of their research. We manage technologies with applications across the widest imaginable

spectrum across the physical and life sciences.

Isis received 356 disclosures of new ideas from Oxford

researchers (up 22% from last year), filed 100 new priority

patent applications, and concluded 113 new technology

transfer deals. These activities are at the heart of our

technology transfer activity for Oxford. We take every

opportunity to engage with researchers through meetings,

seminars, and informal drop-in sessions, providing

guidance on protecting intellectual property, licensing

arrangements and spin-out company formation. Isis

works closely with colleagues across Oxford University

to co-ordinate plans for industry co-operation. Isis adds

valuable insight to University Industrial Liaison Committees,

participates in Open Days, and helps researchers to

commercialise their work thus demonstrating impact – an

important consideration for those seeking further funding.

Further afield, Isis assists universities around the world

to develop technology transfer policies and practices,

conducting due diligence on existing portfolios, and

managing technology projects directly. Contracts with

the University of Liverpool, Aston University and Cranfield

University apply Isis’ knowledge and expertise in all

aspects of technology transfer to support researchers

in these universities. Internationally, Isis has completed

extensive Technology Transfer Partnership work with one

of the major research universities in Malaysia, and has

provided innovation strategy development and knowledge

mapping for the Ruder Boškovic Institute and the University

of Rijeka in Croatia. Working with the senior management

of these institutions, Isis consultants developed innovation

strategies together with recommendations for their

implementation.

Case studies

Nuclear fusion

Research by Professor Yiannis Ventikos and fellow scientists led to

the creation of new Oxford spin-out company, Oxyntix, to accelerate

the validation of their research into bubble collapse. Funding from

IP Group plc, Parkwalk Advisors and angel investors is allowing

development of processes and devices for controlling and intensifying

extreme intensity bubble collapses, with numerous applications in

nuclear fusion power generation and sonochemistry.

Physics consultancy

Oxford University Consulting and the Technology Transfer Group

within Isis have been developing a closer relationship with Oxford’s

Department of Physics to generate more commercial activity between

the Department and external clients. Isis is a member of the

Department’s Industrial Liaison Committee, which is supporting the

notable increase in consulting and services related activity managed

by OUC on behalf of the Department. OUC has facilitated consulting

and services activities with medical instrumentation company Elekta.

OUC set up a framework agreement that allows Elekta scientists to

seek both theoretical and experimental advice and expertise from

researchers in the Department of Physics.

Proof of Concept Funds

The proof of concept funds managed by Isis enable the development

of Oxford inventions into investable propositions. The Oxford Invention

Fund supported a project to develop lead compounds for protecting

the heart from tissue damage following heart attack. The OIF funds

researchers from the Department of Cardiovascular Medicine to

generate sufficient proof-of-principle data to support an application

for further translational research funding. In the long term the team

aims to license or partner with Pharma/Biotech for downstream

development of clinical candidates for the treatment of ischaemia-

reperfusion injury and other cardiovascular diseases.

Isis Software Incubator

This incubator supports Oxford University staff and students to

develop software business ventures by offering technical and

commercial advice, and allowing incubatees to develop their product

and start trading. The Incubator takes willing and energetic founder

entrepreneurs with a concept that has business potential but

requires further work; successful companies eventually leave as

new, standalone, entities – which may subsequently raise money

and apply for patents. Pilio, TheySay, Colwiz, OxGeos, and Esplorio

are amongst the ventures that have entered the Incubator, proving

its success with some ventures already trading profitably and others

being able to raise significant funding towards accelerated growth.

Isis’ many services include optimising patent portfolios for bodies including the Kennedy Institute, now part of Oxford, renowned for their work with monoclonal antibodies.

Page 6: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

7

Working for Industry

Isis works closely with industry around the world to match innovative technologies and expertise with

business development needs. Projects with commercial potential from the research base are introduced

to industrial companies worldwide.

Innovations conceived at Oxford and commercialised by Isis last year included a torque measurement device for the power generation sector.

Isis licenses technologies arising from Oxford University’s

research outputs in a timely and ethical manner to

companies which invest in developing and selling products.

Commercial partners are sought from all technology and

business sectors on an international basis. Isis provides

industry with access to Oxford academic expertise and

research facilities via Oxford University Consulting. OUC

makes expertise drawn from the depth and breadth of

the University of Oxford available to industry. OUC also

arranges access to equipment and facilities based in

University departments.

Isis Enterprise works with industry on projects involving

scouting for technologies to complement current activities

and plans, evaluating intellectual property portfolios to

inform due diligence and IP management strategies,

and supporting in and out licensing programmes. Isis

Enterprise builds on unrivalled awareness of academic

research and innovation management from Oxford and

elsewhere.

The Oxford Innovation Society, established by Isis in 1990,

allows companies to have a ‘window’ on Oxford science

and foster links between the business and the academic

communities. The OIS is a leading forum for open

innovation, bringing industry together with researchers;

Industry is increasingly realising the value of open

innovation, actively seeking technologies and innovations

from outside their own organisations to create competitive

advantage for their businesses.

Case studies

Supporting Oxford spin-outs

Isis provides ongoing support to companies spun-out from Oxford

by licensing new technologies and providing consultancy services.

Oxford Photovoltaics, spun-out in 2010, and Oxford Nanopore

Technologies (ONT), spun-out in 2005, both completed new licence

deals this year. Oxford PV attracted further additional funding in July

and positive press coverage when it joined a delegation of British

cleantech start-up companies on a trade mission to the US. ONT

made headlines in the international media when it announced that it

will start producing a DNA Sequencing machine the size of a USB

Memory Stick. Oxford University Consulting supplied consultancy

services to Yasa Motors, spun-out in 2009. Yasa provided axial flux

motors for the Lola-Drayson B12/69EV electric car which is as fast

as a Formula 1 racer. Yasa Motors was named UK’s Best Enterprise

in the Lloyds TSB/Telegraph Enterprise Awards.

Magnetic Resonance Imaging

The Oxford Centre for Clinical Magnetic Resonance Imaging

Research (OCMR) is a world-leading centre in the research and

use of Magnetic Resonance Imaging and Spectroscopy (MRI

and MRS) for the clinical study of the human heart and brain,

with cutting-edge techniques in functional MRI for brain analysis,

cardiac MRI for capturing the heart cycle and magnetic resonance

spectroscopy (MRS) for for directly measuring metabolic processes

in the heart. MRS offers potential for new insights into the effects

of drugs in the cardiac setting. OCMR has deployed its expertise

and skills through consultancy and service contracts with OUC,

making direct contributions to the development of new medical

approaches that complement OCMR’s research activities. This

type of approach enables external organisations to enhance their

own capabilities in a project-specific manner with the added benefit

of building on relationships with the University for other projects.

Agreements were concluded with Siemens AG. Five patented

technologies with potential for improving MRI performance were

licensed in the deal, and the latest software licensed back to the

University for use by medical researchers.

Biophysics services

OUC works with University Departments to enable external

organisations to access the substantial facilities they posses and

to benefit from the expertise researchers have in applying such

resources for routine and exploratory analysis. The Biophysics Facility

was set up in the Department of Biochemistry at the beginning of

2009 as a central resource for the biophysical analysis of proteins

and other macromolecules. OUC has arranged four commercial

service agreements whereby scientists from external companies

use the facility for routine sample analysis and receive training and

support in the use of analytical instruments to support their own R&D

programmes. The additional income helps the Department provide

its services to University users; companies benefit from access to

equipment and expertise they do not posses internally in a flexible,

cost-effective manner.

Page 7: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

9

Working with Investors

A vital part of Isis’ work is to introduce investors with an interest in early-stage technology to emerging

projects requiring capital and financial management. We manage funds to develop technology concepts

into investable propositions, and organise events to allow investors and researchers to engage.

The Isis Angels Network introduces private and institutional

investors interested in Oxford spin-out companies to

investment opportunities and the teams behind them,

on behalf of the University. Twice yearly meetings of IAN

members and invited guests receive introductions to new

investment propositions, with keynote talks from industry

experts. These events are growing in popularity, and boast

an impressive record for making connections between

investors and projects – each meeting typically makes

introductions that lead to at least one new company being

formed. The global nature of the investment community

is well represented in IAN, and two spin-outs in this year

were wholly or partly funded from outside the UK.

Isis manages the Oxford University Challenge Seed Fund

on behalf of the University to finance work that accelerates

the transfer of Oxford technologies to market. During

the year funds totalling £637k were awarded to six new

projects from the engineering, physical and medical

sciences. The fund has an asset value of £3m and is

currently fully invested.

Isis launched the Oxford Invention Fund (OIF) with the

University’s Development Office as part of Oxford Thinking,

a united Campaign for the collegiate University. The

OIF started operations in June 2011 in parallel with the

UCSF and now has assets in excess of £1m thanks to

donations from alumni, industry partners such as Johnson

& Johnson, and other benefactors. It made six awards

worth £300,000 in total this year. Building on this early

success, fundraising continues with an ambitious target

of £5m that will allow Isis to support the proof of concept

activity for the coming years.

Case studies

International investment in Oxford technology

During an intense period of nine months introductions were made

and meetings held between researchers from Oxford, professional

business advisors, and start-up investors from China. In August 2011

this culminated in the formation of Oxford Multi Spectral – a company

offering portable flatbed scanner technology with enormous potential

in the security and identity markets. Originally developed for research

into ancient papyri and manuscripts at Oxford University’s Faculty of

Classics, the scanner uses discrete colour scans made at specific

wavelengths over an extended spectral range, revealing detail

previously hidden from view. Isis and the Chinese investor had built

up a relationship over recent years allowing in-depth evaluation of the

technical and business potential of technologies from Oxford.

Global giant adopts Oxford discoveries

Isis licensed Oxford’s CancerNav biomarker technology to a new

spin-out company, Oxford Cancer Biomarkers, in a deal which

attracted funding of £3m from global biopharmaceutical services

company Quintiles. This first round investment from Quintiles forms

part of a strategic alliance that will enable OCB to establish research

facilities in Oxford to develop a range of predictive biomarkers, the

first of which were developed by the founders, Professor La Thangue

and Professor Kerr at the University of Oxford.

Investment vehicle to nurture emerging technologies

The Fundación Barrié is a Spanish charitable foundation whose mission

includes the support of scientific research. Together Fundación Barrié

and Isis have created a Technology Fund designed to build on the

work of researchers based in Galicia, Spain. The Fund will support

promising projects in diverse fields of study including aquaculture,

biotechnology, energy and nanotechnology. It seeks to generate

returns as a share of licensing revenues or spinout shareholdings.

Long term relationships

Isis works closely with investors IP Group and Technikos in the

fields of Chemistry and Biomedical Engineering as a result of

landmark IP financing deals with the University of Oxford. In 2000

Beeson Gregory, which went on to establish IP Group, paid the

University £20m in return for a share of the University’s returns from

commercialising intellectual property from the Chemistry Department.

Technikos concluded a similar deal in 2006 for £12m to support the

University’s new Institute of Biomedical Engineering. IP Group and

Technikos have invested successfully in a number of spin-outs at the

first and follow-on rounds. Investment funding is crucial to get early-stage ventures established – Isis works closely with individual and institutional investors.

Page 8: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

11

Working with Government

Isis’ experience of successfully launching innovative technologies over two decades provides a fount

of knowledge that leads to invitations to participate in high level debates and policy making with

governments and other third sector bodies worldwide.

UK Universities and Science Minister, David Willets,

addressed the Oxford Innovation Society, and emphasised

the importance of universities to enterprise and growth,

with the obvious benefit of innovative research that drives

business, and more besides. Isis spin-out companies

including Eykona Technologies were subsequently

highlighted in a UK government report, ‘Innovation and

Research Strategy for Growth’, and Isis was cited for its

ability to draw out unexploited university potential in a

speech by the Minister.

Isis contributed to a study by the UK Science and

Technology Select Committee of the UK Parliament with a

submission encouraging more support, direct and indirect,

to scale-up small businesses such as university spin-outs

into big companies.

Visits from high-level Chinese and Spanish Government

ministers reflected the work being done by Isis in those

countries.

Case studies

Oxford University Hospitals NHS Trust

In November 2011 the formation of the Oxford University Hospitals

NHS Trust was announced, with Isis in a key IP management role,

responsible for the management and commercial exploitation both of

jointly owned IP, and also IP owned solely by the Trust.

Four major local hospitals are party to the agreement, which

formalises working relationships for the benefit of researchers,

students, patients and the community. Under the agreement IP

exploitation entails active consideration of patient benefit as well as

commercial return.

UK Government support

Isis Enterprise provided interim programme management to

the UK’s Waste & Resources Action Programme (WRAP). The

programme developed and tested composting technologies and

markets for products, and managed the food and drink supply

chain programme to reduce packaging and food waste in the

retail sector. Isis also worked with WRAP’s team contributing to

the UK Government’s Foresight activity on ‘How To Feed a Global

Population of 9 billion by 2050’.

International business

Training and international commercialisation support were provided

by Isis Enterprise for institutes and companies operating in the

Tomsk Region of Siberia, Russia. Local Tomsk companies were

invited to submit their applications for inclusion in a support

program evaluated by Isis consultants. Isis provided Training

Programs in Oxford and Tomsk, and assisted with IP Protection,

Product Design and Business Modelling Support. By identifying

international partnering opportunities the project resulted in

several partnerships being established between Russian and

European businesses.

Augmented Reality

Isis licensed Parallel Tracking and Mapping (PTAM) augmented

reality software to 2D3, an Oxford based company which delivers

imaging exploitation technology to extract, manipulate, combine,

create and enhance video footage. 2D3 utilised PTAM along with

considerable in-house expertise to deliver a prototype to the UK

Ministry of Defence.

Oxford Department of Education

Oxford University Consulting supports the University’s Department

of Education in their programme of active engagement with external

organisations, helping to make a positive societal impact through

department-based consultancy projects. Through consultancy,

the department is actively applying its research to support many

key challenges facing education today, including engagement with

nursery organisations, school improvement programmes, appren-

ticeships, financial education in schools, and vocational education

and training across Europe. Through OUC, the Department is able to

provide consultancy to a wide range of clients such as NGOs, charity

organisations, international bodies, governments and educational

consultancy firms.Isis works with governments and 3rd-Sector bodies in the UK and worldwide.

Page 9: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

13

Communications International Platforms

It is a fundamental requirement of our business that partners and customers know about Isis, and

understand what we do. In our marketing activities we aim to provide insight and access to the

world-leading science and technology from today’s researchers at the University of Oxford and

elsewhere, building on the historic legacy of University of Oxford research.

By explaining and promoting Isis’ role in the innovation ecosystem,

we encourage dialogue with our business partners, using a variety of

communications channels.

The Isis website is regularly updated with news of technologies from

Oxford and elsewhere that are being adopted by our industry partners,

many of these stories are also promoted to the media.

We publish printed brochures such as this Annual Report and our

quarterly ‘Isis Insights’ to summarise the latest technologies available

and to highlight the contribution of Isis to applying academic expertise to

technology development worldwide. This is one aspect of our extensive

marketing activities in print and electronic media.

Electronic newsletters are sent to subscribers in English and Chinese.

LinkedIn and Twitter have enabled us to broaden our engagement with

contacts worldwide, and to encourage dialogue and media sharing, helping

us to maintain existing links and reach new business partners.

Nothing can replace face-to-face meetings, and Isis arranges frequent

events both within the University and in the business, industry and

financial communities. The Oxford Innovation Society continues to be

a powerful networking organisation bringing together key participants

in Open Innovation. Internally we arranged or attended more than 100

internal events to introduce the services that Isis can offer to researchers

at the University of Oxford.

Subscribe at www.isis-innovation.com to receive Isis Insights and Isis

Technology Updates, or connect using LinkedIn and Twitter.

By its very nature technology commercialisation is an international activity.

One of the key differentiators of the Oxford model of technology transfer is the extent to which we embrace international

collaboration through cross border joint development, cross border licensing, and the creation of spin-out companies

backed by overseas as well as UK based investors.

Building on Isis experience in global business, over the last 12 months we have accelerated our access to overseas

markets by creating and growing a series of overseas platforms. Typically our international platforms are staffed by

individuals with a sound understanding of their local business culture, native level language skills, excellent senior level

contacts and experience in international technology commercialisation.

Our platforms provide support to all divisions of Isis and all researchers from Oxford and beyond by finding and evaluating

potential collaborators. During the business of negotiations the international staff are on hand to make regular visits to

potential partners to understand and deal with negotiation hurdles.

The first four international platforms are:

spain

The Spanish government has invested heavily in innovation over the last 20 years. With support from

local partners Isis has been working locally and nationally to facilitate the marketing of technology

innovations and products to Spanish and overseas partners.

Hong Kong

Isis Innovation (Hong Kong) Limited is a wholly owned subsidiary company of Isis Innovation

Limited. The company employs a local team of experienced Isis staff supplemented by associates

based in Hong Kong and across the border in mainland China. The activities of the Hong Kong

office include oversight of all Asia based Isis business including schemes to facilitate the smooth

transfer of international technologies, products and companies into mainland China.

China

Following three years of work in Changzhou, Jiangsu province Isis has worked to create the first of

a series of International Technology Transfer Centres backed by the city and provincial governments

and a group of private investors who happen to be Oxford alumni. The initial focus of the Changzhou

platform is cross border collaboration in pharmaceuticals, chemicals, medical devices and medical

diagnostics. A team of consultants from Isis undertook a programme of work in support of the

plans for the Changzhou Biopharmaceutical Incubator in China. Preparatory investigations led to a

two stage report on suggested, and then agreed, incubator services including options for provision

of some services, tuned to address the norms of Chinese culture. This was followed with a draft

financial model, standard operating procedures for delivery of each of the incubator services and a

suggested organisational structure.

Japan

The Isis office in Kyoto, western Japan provides us with access to the local portfolio of leading

electronics and pharmaceuticals companies looking to source innovation from Europe and exploit

their own innovations in overseas markets.

12

IiIssu

e 6

6 W

inte

r 1

1

Also: Pre-eclampsia diagnostic, migration study, Tomsk technologies and more

Isis insights

The latest innovations, collaborations and technology transfer

Cognitive developments

Isis insights

IiThe latest innovations, collaborations and technology transfer

Issu

e 65 A

utu

mn 1

1

Engineering advancesThe physical possibilities...

Isis insights

IiThe latest innovations, collaborations and technology transfer

Issu

e 64 S

um

mer

11

Conservation & creationResearch and the environment

IiIssu

e 6

7 S

pri

ng 1

2

Also inside: Tumour detection, torque, aviation safety and more

Isis insights

The latest innovations, collaborations and technology transfer

No-hands navigation

Subscribe to printed and online publications

from the Isis website

@IsisInnovation

www.linkedin.com/company/ isis-innovation-ltd.

Page 10: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

15

Income

Isis total income comes from sales Turnover of £10.2m

and the University subvention of £2.5m. Sales Turnover is

made up of Technology Transfer licensing income, Oxford

University Consulting income, Isis Enterprise consulting

income, and OIS membership subscriptions. Isis receives

a subvention from the University of £2.5m per annum for

investment into Oxford technology transfer project costs,

the majority of which is invested in patenting inventions

from researchers. Isis also receives an allocation of the

University’s Higher Education Innovation Fund award to

support OUC and marketing activities. These amounts

are shown in the accounts in ‘Other operating income’.

spin-out company shareholdings

Shares in Oxford University spin-out companies set up by Isis are owned by the University of Oxford, and not by Isis

Innovation Ltd. They do not therefore appear in the Isis Innovation Ltd accounts either as assets on the balance sheet or

showing income from realisations of shares or the payment of dividends from shares. The total value of the University’s

shares in its spin-out companies at 31 July 2012 was £45m.

expenditure

The University subvention is invested in patents and

other project costs incurred on Oxford technology

transfer projects. Administrative expenses are the costs

of running Isis which include our staff costs, marketing

and office expenses. Isis distributes the net technology

transfer licensing income and OUC income to the

University and its researchers according to University

rules; these outgoings are both included in ‘Cost of

sales’ in the accounts. Isis pays its taxable profit to the

University under gift aid.

Accounts 2012

Profit & Loss Account1

Year to 31 March 2012 2011

£’000 £’000

Turnover £10,201 £8,300

Cost of Sales -£7,798 -£6,462

Gross Profit £2,403 £1,838

Administrative expenses -£5,293 -£3,974

Other operating income £2,982 £2,895

Operating profit / loss £92 £759

Other interest receivable £10 £8

Profit on ordinary activities before gift aid and taxation

£102 £767

Gift aid payable to university of Oxford -£343 -£784

Profit / loss on ordinary activities after gift aid donation and before taxation

-£241 -£17

Taxation £0 £0

Profit / loss on ordinary activities after Gift Aid donation and after taxation

-£241 -£17

balance sheet 1

Year to 31 March 2012 2011

£’000 £’000

Assets (fixed & current)

Tangible Assets £18 £54

Debtors £3,118 £2,543

Cash at bank and in hand £1,144 £1,369

£4,280 £3,966

Creditors -£3,134 -£2,578

net assets / liabilities £1,147 £1,388

Capital Funds

Share capital £1,750 £1,750

Profit & Loss account -£603 -£362

shareholder funds £1,147 £1,388

Isis Innovation Ltd is wholly owned by the University of Oxford.

Isis Innovation (Hong Kong) Ltd is a wholly owned subsidiary of Isis Innovation Ltd.

Isis performance from 2000

notes

A full set of accounts is available from Isis Innovation Ltd. 1 Isis distributes these sums to the University and individuals. The University in turn distributes these sums to individuals, Departments, and central 2 accounts according to its standard procedures. This sum also includes the amount paid as gift aid by Isis to the University.

£0

£1m

£2m

£3m

£4m

£5m

£6m

£7m

£8m

£9m

£10m

£11m

2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Sales Income

Distributions& Covenant to University & Researchers2

Investment in Projects & Patents

Income & expenditure 1

£0

£2,000,000

£4,000,000

£6,000,000

£8,000,000

£10,000,000

£12,000,000

£14,000,000

Income Expenditure

Payments to University & Researchers

Technology Transfer Project support

Administrative expenses

University subvention

Oxford University Consulting

Technology Transfer

Isis Enterprise

Oxford Innovation Society, other

14

Page 11: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

17

COMPANY DETAILS

Chairman Mr Bernard Taylor

Managing Director Mr Tom Hockaday

non-executive Directors Professor Sir John Bell Regius Professor of Medicine, University of Oxford

Dr Tim Cook Non-Executive Director

Professor Steve Davies Professor of Chemistry, University of Oxford

Mrs Ann Hacker Non-Executive Director

Mr Nigel Keen Chairman, Oxford Instruments

Mr Giles Kerr Finance Director, University of Oxford

Professor Ewan McKendrick Registrar, University of Oxford

Professor Lionel Tarassenko Director, Institute for Biomedical Engineering, University of Oxford

Company secretary Mr William Colquhoun University Finance Division

Auditors Deloitte LLP

Isis Innovation Ltd

Registered Office University Offices, Wellington Square, Oxford OX1 2JD

Address

Company Number 2199542

VAT Number 490798885

Design by Franks and Franks. Printed by Rumbold Holland to meet ISO 14001 standards, on Forest Stewardship Council (FSC®) accredited paper stock.

Isis Innovation Ltd

Ewert House, Ewert Place,

Summertown, Oxford OX2 7SG

T 01865 280830

F 01865 280831

E [email protected]

www.isis-innovation.com

Isis Innovation (Hong Kong) Ltd

Level 12, Infinitus Plaza,

199 Des Voeux Road Central,

Sheung Wan, Hong Kong SAR

T +852 3796 3581

E [email protected]

Isis Innovation Japan Office

ASTEM Building, Kyoto Research Park,

134 Minami-macho,

Chudoji-machi, Shimogyo-ku,

Kyoto 600-8813

T +81 75 315 8560

Isis Innovation spain Office

Calle Orense 104C

Madrid 28020

Spain

T +34 630 816 286

16

Page 12: The research commercialisation office of the University of ......conducting due diligence on existing portfolios, and managing technology projects directly. Contracts with the University

Isis Innovation Ltd

Ewert House, Ewert Place, Summertown, Oxford OX2 7SG

T +44 (0)1865 280830 F +44 (0)1865 280831

E [email protected] www.isis-innovation.com

Isis Innovation Ltd Annual Report 2012


Recommended